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Obesity due to leptin receptor gene deficiency
Leptin receptor deficiency is characterized by severe early-onset obesity, major hyperphagia, hypogonadotropic hypogonadism, and neuroendocrine/metabolic dysfunction (summary by Dehghani et al., 2018). [from OMIM]
Abnormal hypothalamus morphology
Any structural anomaly of the hypothalamus. [from HPO]
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