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Pseudofolliculitis barbae(PFB)

MedGen UID:
107807
•Concept ID:
C0549150
•
Disease or Syndrome
Synonyms: INGROWN HAIRS; PFB; PILI INCARNATI; Pseudofolliculitis barbae, susceptibility to
SNOMED CT: Pseudofolliculitis barbae (399205006)
 
Gene (location): KRT75 (12q13.13)
 
Monarch Initiative: MONDO:0012865
OMIM®: 612318

Professional guidelines

PubMed

Pseudofolliculitis Barbae: A Review of Current Treatment Options.
Nussbaum D, Friedman A
J Drugs Dermatol 2019 Mar 1;18(3):246-250. PMID: 30909328
Folliculitis keloidalis nuchae and pseudofolliculitis barbae: are prevention and effective treatment within reach?
Alexis A, Heath CR, Halder RM
Dermatol Clin 2014 Apr;32(2):183-91. doi: 10.1016/j.det.2013.12.001. PMID: 24680005
Pathogenesis and treatment of pseudofolliculitis barbae.
Brown LA Jr
Cutis 1983 Oct;32(4):373-5. PMID: 6354618

Recent clinical studies

Etiology

Evaluation of efficacy and safety of chemical peeling and long-pulse Nd:YAG laser in treatment of pseudofolliculitis barbae.
Amer A, Elsayed A, Gharib K
Dermatol Ther 2021 Mar;34(2):e14859. Epub 2021 Feb 28 doi: 10.1111/dth.14859. PMID: 33559240
Considerations When Treating Cosmetic Concerns in Men of Color.
Awosika O, Burgess CM, Grimes PE
Dermatol Surg 2017 Nov;43 Suppl 2:S140-S150. doi: 10.1097/DSS.0000000000001376. PMID: 29064976
Keratin disorders: from gene to therapy.
McLean WH, Moore CB
Hum Mol Genet 2011 Oct 15;20(R2):R189-97. Epub 2011 Sep 2 doi: 10.1093/hmg/ddr379. PMID: 21890491
Pseudofolliculitis barbae and acne keloidalis nuchae.
Kelly AP
Dermatol Clin 2003 Oct;21(4):645-53. doi: 10.1016/s0733-8635(03)00079-2. PMID: 14717405
The causes and treatment of pseudofolliculitis barbae.
Crutchfield CE 3rd
Cutis 1998 Jun;61(6):351-6. PMID: 9640558

Diagnosis

Pseudofolliculitis Barbae.
Patel TS, Dalia Y
JAMA Dermatol 2022 Jun 1;158(6):708. doi: 10.1001/jamadermatol.2022.0077. PMID: 35475875
Dermatologic Conditions in Transgender Populations.
Yeung H, Kahn B, Ly BC, Tangpricha V
Endocrinol Metab Clin North Am 2019 Jun;48(2):429-440. doi: 10.1016/j.ecl.2019.01.005. PMID: 31027550Free PMC Article
Pseudofolliculitis barbae: understanding the condition and the role of facial grooming.
Gray J, McMichael AJ
Int J Cosmet Sci 2016 Jun;38 Suppl 1:24-7. doi: 10.1111/ics.12331. PMID: 27212468
Ethnic hair disorders.
Lindsey SF, Tosti A
Curr Probl Dermatol 2015;47:139-49. Epub 2015 Feb 20 doi: 10.1159/000369414. PMID: 26370652
Defining pseudofolliculitis barbae in 2001: a review of the literature and current trends.
Perry PK, Cook-Bolden FE, Rahman Z, Jones E, Taylor SC
J Am Acad Dermatol 2002 Feb;46(2 Suppl Understanding):S113-9. doi: 10.1067/mjd.2002.120789. PMID: 11807473

Therapy

Review of treatments for pseudofolliculitis barbae.
Dalia Y, Khatib J, Odens H, Patel T
Clin Exp Dermatol 2023 Jun 5;48(6):591-598. doi: 10.1093/ced/llad075. PMID: 36840647
Dermatologic Conditions in Transgender Populations.
Yeung H, Kahn B, Ly BC, Tangpricha V
Endocrinol Metab Clin North Am 2019 Jun;48(2):429-440. doi: 10.1016/j.ecl.2019.01.005. PMID: 31027550Free PMC Article
Pseudofolliculitis barbae: understanding the condition and the role of facial grooming.
Gray J, McMichael AJ
Int J Cosmet Sci 2016 Jun;38 Suppl 1:24-7. doi: 10.1111/ics.12331. PMID: 27212468
Ethnic hair disorders.
Lindsey SF, Tosti A
Curr Probl Dermatol 2015;47:139-49. Epub 2015 Feb 20 doi: 10.1159/000369414. PMID: 26370652
The medical and surgical therapy of pseudofolliculitis barbae.
Bridgeman-Shah S
Dermatol Ther 2004;17(2):158-63. doi: 10.1111/j.1396-0296.2004.04016.x. PMID: 15113283

Prognosis

Pseudofolliculitis barbae treatment: Efficacy of topical eflornithine, long-pulsed Nd-YAG laser versus their combination.
Shokeir H, Samy N, Taymour M
J Cosmet Dermatol 2021 Nov;20(11):3517-3525. Epub 2021 Mar 9 doi: 10.1111/jocd.14027. PMID: 33629488
Red face revisited: Disorders of hair growth and the pilosebaceous unit.
Ramos-e-Silva M, Pirmez R
Clin Dermatol 2014 Nov-Dec;32(6):784-99. Epub 2014 Mar 1 doi: 10.1016/j.clindermatol.2014.02.018. PMID: 25441472
Shave frequency and regimen variation effects on the management of pseudofolliculitis barbae.
Daniel A, Gustafson CJ, Zupkosky PJ, Candido A, Kemp HR, Russell G, McMichael A
J Drugs Dermatol 2013 Apr;12(4):410-8. PMID: 23652888
Pseudofolliculitis barbae and acne keloidalis nuchae.
Kelly AP
Dermatol Clin 2003 Oct;21(4):645-53. doi: 10.1016/s0733-8635(03)00079-2. PMID: 14717405
Defining pseudofolliculitis barbae in 2001: a review of the literature and current trends.
Perry PK, Cook-Bolden FE, Rahman Z, Jones E, Taylor SC
J Am Acad Dermatol 2002 Feb;46(2 Suppl Understanding):S113-9. doi: 10.1067/mjd.2002.120789. PMID: 11807473

Clinical prediction guides

Review of treatments for pseudofolliculitis barbae.
Dalia Y, Khatib J, Odens H, Patel T
Clin Exp Dermatol 2023 Jun 5;48(6):591-598. doi: 10.1093/ced/llad075. PMID: 36840647
Laser and Light-Based Aesthetics in Men.
Green JB, Metelitsa AI, Kaufman J, Keaney T
J Drugs Dermatol 2015 Sep;14(9):1061-4. PMID: 26355628
Direct comparison of EMLA versus lidocaine for pain control in Nd:YAG 1,064 nm laser hair removal.
Guardiano RA, Norwood CW
Dermatol Surg 2005 Apr;31(4):396-8. doi: 10.1111/j.1524-4725.2005.31104. PMID: 15871313
Treatment of pseudofolliculitis barbae in skin types IV, V, and VI with a long-pulsed neodymium:yttrium aluminum garnet laser.
Ross EV, Cooke LM, Timko AL, Overstreet KA, Graham BS, Barnette DJ
J Am Acad Dermatol 2002 Aug;47(2):263-70. doi: 10.1067/mjd.2002.124081. PMID: 12140474
Treatment of pseudofolliculitis with a pulsed infrared laser.
Kauvar AN
Arch Dermatol 2000 Nov;136(11):1343-6. doi: 10.1001/archderm.136.11.1343. PMID: 11074696

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    • ClinVar
      Related medical variations
    • Gene
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    • GTR
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    • GTR(Clinical)
      Clinical tests in GTR
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      Related records in OMIM
    • OMIM(Genes)
      OMIM records containing genes associated with phenotypes registered in MedGen
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