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Hypoplasia of the anterior nasal spine

MedGen UID:
869325
•Concept ID:
C4023751
•
Anatomical Abnormality
Synonyms: Decreased length of anterior nasal spine; Decreased projection of anterior nasal spine; Decreased size of anterior nasal spine; Deficiency of anterior nasal spine; Hypotrophic anterior nasal spine; Small anterior nasal spine; Underdevelopment of anterior nasal spine
 
HPO: HP:0010666

Definition

Underdevelopment of the anterior nasal spine of maxilla. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHypoplasia of the anterior nasal spine

Professional guidelines

PubMed

Unilateral Cleft Lip Nasal Deformity: Three-Dimensional Analysis of the Primary Deformity and Longitudinal Changes following Primary Correction of the Nasal Foundation.
Tse RW, Knight R, Oestreich M, Rosser M, Mercan E
Plast Reconstr Surg 2020 Jan;145(1):185-199. doi: 10.1097/PRS.0000000000006389. PMID: 31592947
The Influence of Four Different Treatment Protocols on Maxillofacial Growth in Patients with Unilateral Complete Cleft Lip, Palate, and Alveolus.
Xu X, Cao C, Zheng Q, Shi B
Plast Reconstr Surg 2019 Jul;144(1):180-186. doi: 10.1097/PRS.0000000000005711. PMID: 31246827
Nasal malformations associated with unilateral cleft lip. Accurate diagnosis and management.
Talmant JC
Scand J Plast Reconstr Surg Hand Surg 1993 Sep;27(3):183-91. doi: 10.3109/02844319309078110. PMID: 8272769

Recent clinical studies

Etiology

Influence of Nonsyndromic Bicoronal Synostosis and Syndromic Influences on Orbit and Periorbital Malformation.
Lu X, Forte AJ, Dinis J, Junn A, Alperovich M, Alonso N, Persing JA
Plast Reconstr Surg 2022 May 1;149(5):930e-942e. Epub 2022 Mar 14 doi: 10.1097/PRS.0000000000009051. PMID: 35286288
Anteroposterior length of the maxillary complex and its relationship with the anterior cranial base.
Savoldi F, Massetti F, Tsoi JKH, Matinlinna JP, Yeung AWK, Tanaka R, Paganelli C, Bornstein MM
Angle Orthod 2021 Jan 1;91(1):88-97. doi: 10.2319/020520-82.1. PMID: 33289836Free PMC Article
Airway Analysis in Apert Syndrome.
Forte AJ, Lu X, Hashim PW, Steinbacher DM, Alperovich M, Persing JA, Alonso N
Plast Reconstr Surg 2019 Sep;144(3):704-709. doi: 10.1097/PRS.0000000000005937. PMID: 31461034
Bony Fixation of the Nasal Framework.
Haack S, Hacker S, Mann S, Gubisch W
Facial Plast Surg 2019 Feb;35(1):23-30. Epub 2019 Feb 13 doi: 10.1055/s-0039-1677767. PMID: 30759458
Refinements in extracorporal septoplasty.
Gubisch W, Constantinescu MA
Plast Reconstr Surg 1999 Sep;104(4):1131-9; discussion 1140-2. doi: 10.1097/00006534-199909040-00038. PMID: 10654757

Diagnosis

Posteroinferior septal defect due to vomeral malformation.
Lee YW, Yoon YH, Song K, Kim YM
Eur Arch Otorhinolaryngol 2019 Aug;276(8):2229-2235. Epub 2019 Apr 25 doi: 10.1007/s00405-019-05443-3. PMID: 31025110
The relationship between lateral displacement of the mandible and scoliosis.
Nakashima A, Nakano H, Yamada T, Inoue K, Sugiyama G, Kumamaru W, Nakajima Y, Sumida T, Yokoyama T, Mishiama K, Mori Y
Oral Maxillofac Surg 2017 Mar;21(1):59-63. Epub 2016 Dec 30 doi: 10.1007/s10006-016-0607-9. PMID: 28039546
Anterior plagiocephaly: epidemiology, clinical findings,diagnosis, and classification. A review.
Di Rocco C, Paternoster G, Caldarelli M, Massimi L, Tamburrini G
Childs Nerv Syst 2012 Sep;28(9):1413-22. Epub 2012 Aug 8 doi: 10.1007/s00381-012-1845-2. PMID: 22872257
Sella-Nasion line revisited.
Sarhan OA
J Oral Rehabil 1995 Dec;22(12):905-8. doi: 10.1111/j.1365-2842.1995.tb00239.x. PMID: 9217302
Nasal malformations associated with unilateral cleft lip. Accurate diagnosis and management.
Talmant JC
Scand J Plast Reconstr Surg Hand Surg 1993 Sep;27(3):183-91. doi: 10.3109/02844319309078110. PMID: 8272769

Therapy

Hypothalamic-pituitary sarcoidosis with vision loss and hypopituitarism: case series and literature review.
Anthony J, Esper GJ, Ioachimescu A
Pituitary 2016 Feb;19(1):19-29. doi: 10.1007/s11102-015-0678-x. PMID: 26267304
Role of the sphenoidal process of the septal cartilage in the development of septal deviation.
Kim J, Kim SW, Kim SW, Cho JH, Park YJ
Otolaryngol Head Neck Surg 2012 Jan;146(1):151-5. Epub 2011 Oct 10 doi: 10.1177/0194599811425000. PMID: 21987650
The measurement of congenital nasal pyriform aperture stenosis in infant.
Lee JC, Yang CC, Lee KS, Chen YC
Int J Pediatr Otorhinolaryngol 2006 Jul;70(7):1263-7. Epub 2006 Mar 15 doi: 10.1016/j.ijporl.2006.01.005. PMID: 16540178
Subnasal modified Le Fort I for nasolabial aesthetics improvement.
Becelli R, De Ponte FS, Fadda MT, Govoni FA, Iannetti G
J Craniofac Surg 1996 Sep;7(5):399-402. doi: 10.1097/00001665-199609000-00015. PMID: 9133854
Sella-Nasion line revisited.
Sarhan OA
J Oral Rehabil 1995 Dec;22(12):905-8. doi: 10.1111/j.1365-2842.1995.tb00239.x. PMID: 9217302

Prognosis

Bony Fixation of the Nasal Framework.
Haack S, Hacker S, Mann S, Gubisch W
Facial Plast Surg 2019 Feb;35(1):23-30. Epub 2019 Feb 13 doi: 10.1055/s-0039-1677767. PMID: 30759458
Nasal Root Deviation in Unicoronal Craniosynostosis: A Craniometric Analysis of Early and Late Postoperative Outcomes.
Wes AM, Mazzaferro D, Naran S, Bartlett SP, Taylor JA
J Craniofac Surg 2017 Jul;28(5):1220-1223. doi: 10.1097/SCS.0000000000003665. PMID: 28570405
Anterior plagiocephaly: epidemiology, clinical findings,diagnosis, and classification. A review.
Di Rocco C, Paternoster G, Caldarelli M, Massimi L, Tamburrini G
Childs Nerv Syst 2012 Sep;28(9):1413-22. Epub 2012 Aug 8 doi: 10.1007/s00381-012-1845-2. PMID: 22872257
Role of the sphenoidal process of the septal cartilage in the development of septal deviation.
Kim J, Kim SW, Kim SW, Cho JH, Park YJ
Otolaryngol Head Neck Surg 2012 Jan;146(1):151-5. Epub 2011 Oct 10 doi: 10.1177/0194599811425000. PMID: 21987650
Caudal nasal deviation.
Guyuron B, Behmand RA
Plast Reconstr Surg 2003 Jun;111(7):2449-57; discussion 2458-9. doi: 10.1097/01.PRS.0000060802.70218.FE. PMID: 12794495

Clinical prediction guides

Simultaneous Le Fort III and Le Fort I Osteotomy: Surgical Outcomes and Clinical Parameters.
Yue OY, Kalra A, Eisemann BS, Grayson BH, McCarthy JG, Flores RL, Staffenberg DA, Rodriguez ED, Shetye PR
J Craniofac Surg 2023 Jan-Feb 01;34(1):222-226. Epub 2022 Oct 18 doi: 10.1097/SCS.0000000000009066. PMID: 36253918
Influence of Nonsyndromic Bicoronal Synostosis and Syndromic Influences on Orbit and Periorbital Malformation.
Lu X, Forte AJ, Dinis J, Junn A, Alperovich M, Alonso N, Persing JA
Plast Reconstr Surg 2022 May 1;149(5):930e-942e. Epub 2022 Mar 14 doi: 10.1097/PRS.0000000000009051. PMID: 35286288
Does the Timing of 1-Stage Palatoplasty With Radical Muscle Dissection Effect Long-Term Midface Growth? A Single-Center Retrospective Analysis.
Shetty V, Patteta NK, Yadav A, Bahl D, Sailer HF
Cleft Palate Craniofac J 2022 Feb;59(2):239-245. Epub 2021 May 6 doi: 10.1177/10556656211013174. PMID: 33955252
Anterior plagiocephaly: epidemiology, clinical findings,diagnosis, and classification. A review.
Di Rocco C, Paternoster G, Caldarelli M, Massimi L, Tamburrini G
Childs Nerv Syst 2012 Sep;28(9):1413-22. Epub 2012 Aug 8 doi: 10.1007/s00381-012-1845-2. PMID: 22872257
Caudal nasal deviation.
Guyuron B, Behmand RA
Plast Reconstr Surg 2003 Jun;111(7):2449-57; discussion 2458-9. doi: 10.1097/01.PRS.0000060802.70218.FE. PMID: 12794495

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