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Staphylococcal pneumonia

MedGen UID:
18532
•Concept ID:
C0032308
•
Disease or Syndrome
Synonyms: Pneumonia, Staphylococcal; Pneumonias, Staphylococcal; Staphylococcal Pneumonia; Staphylococcal Pneumonias
SNOMED CT: Staphylococcal pneumonia (22754005)
 
Monarch Initiative: MONDO:0005970

Definition

Pneumonia caused by infections with bacteria of the genus staphylococcus, usually with staphylococcus aureus. [from MONDO]

Professional guidelines

PubMed

Aetiology, diagnosis and management of infective causes of severe haemoptysis in intensive care units.
Fartoukh M, Parrot A, Khalil A
Curr Opin Pulm Med 2008 May;14(3):195-202. doi: 10.1097/MCP.0b013e3282f79663. PMID: 18427242
Diagnosis and treatment of Panton-Valentine leukocidin (PVL)-associated staphylococcal pneumonia.
Morgan MS
Int J Antimicrob Agents 2007 Oct;30(4):289-96. Epub 2007 Jul 12 doi: 10.1016/j.ijantimicag.2007.04.019. PMID: 17629464
Hospital-acquired pneumonia: risk factors, clinical features, management, and antibiotic resistance.
Leroy O, Soubrier S
Curr Opin Pulm Med 2004 May;10(3):171-5. doi: 10.1097/00063198-200405000-00005. PMID: 15071367

Recent clinical studies

Etiology

Current pharmacotherapy for methicillin-resistant Staphylococcus aureus (MRSA) pneumonia.
Bassetti M, Labate L, Melchio M, Robba C, Battaglini D, Ball L, Pelosi P, Giacobbe DR
Expert Opin Pharmacother 2022 Feb;23(3):361-375. Epub 2021 Dec 9 doi: 10.1080/14656566.2021.2010706. PMID: 34882041
Staphylococcus aureus Pneumonia in the Community.
He H, Wunderink RG
Semin Respir Crit Care Med 2020 Aug;41(4):470-479. Epub 2020 Jun 10 doi: 10.1055/s-0040-1709992. PMID: 32521547
Childhood pneumonia in low-and-middle-income countries: An update.
Marangu D, Zar HJ
Paediatr Respir Rev 2019 Nov;32:3-9. Epub 2019 Jun 26 doi: 10.1016/j.prrv.2019.06.001. PMID: 31422032Free PMC Article
Staphylococcus aureus Community-acquired Pneumonia: Prevalence, Clinical Characteristics, and Outcomes.
Self WH, Wunderink RG, Williams DJ, Zhu Y, Anderson EJ, Balk RA, Fakhran SS, Chappell JD, Casimir G, Courtney DM, Trabue C, Waterer GW, Bramley A, Magill S, Jain S, Edwards KM, Grijalva CG
Clin Infect Dis 2016 Aug 1;63(3):300-9. Epub 2016 May 8 doi: 10.1093/cid/ciw300. PMID: 27161775Free PMC Article
The ZEPHyR study: a randomized comparison of linezolid and vancomycin for MRSA pneumonia.
Chavanet P
Med Mal Infect 2013 Dec;43(11-12):451-5. Epub 2013 Nov 13 doi: 10.1016/j.medmal.2013.09.011. PMID: 24238896

Diagnosis

Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America.
Metlay JP, Waterer GW, Long AC, Anzueto A, Brozek J, Crothers K, Cooley LA, Dean NC, Fine MJ, Flanders SA, Griffin MR, Metersky ML, Musher DM, Restrepo MI, Whitney CG
Am J Respir Crit Care Med 2019 Oct 1;200(7):e45-e67. doi: 10.1164/rccm.201908-1581ST. PMID: 31573350Free PMC Article
Childhood pneumonia in low-and-middle-income countries: An update.
Marangu D, Zar HJ
Paediatr Respir Rev 2019 Nov;32:3-9. Epub 2019 Jun 26 doi: 10.1016/j.prrv.2019.06.001. PMID: 31422032Free PMC Article
The Clinical Utility of Methicillin-Resistant Staphylococcus aureus (MRSA) Nasal Screening to Rule Out MRSA Pneumonia: A Diagnostic Meta-analysis With Antimicrobial Stewardship Implications.
Parente DM, Cunha CB, Mylonakis E, Timbrook TT
Clin Infect Dis 2018 Jun 18;67(1):1-7. doi: 10.1093/cid/ciy024. PMID: 29340593
Staphylococcus aureus Community-acquired Pneumonia: Prevalence, Clinical Characteristics, and Outcomes.
Self WH, Wunderink RG, Williams DJ, Zhu Y, Anderson EJ, Balk RA, Fakhran SS, Chappell JD, Casimir G, Courtney DM, Trabue C, Waterer GW, Bramley A, Magill S, Jain S, Edwards KM, Grijalva CG
Clin Infect Dis 2016 Aug 1;63(3):300-9. Epub 2016 May 8 doi: 10.1093/cid/ciw300. PMID: 27161775Free PMC Article
Purulent pericarditis.
Sinzobahamvya N, Ikeogu MO
Arch Dis Child 1987 Jul;62(7):696-9. doi: 10.1136/adc.62.7.696. PMID: 3632015Free PMC Article

Therapy

Current pharmacotherapy for methicillin-resistant Staphylococcus aureus (MRSA) pneumonia.
Bassetti M, Labate L, Melchio M, Robba C, Battaglini D, Ball L, Pelosi P, Giacobbe DR
Expert Opin Pharmacother 2022 Feb;23(3):361-375. Epub 2021 Dec 9 doi: 10.1080/14656566.2021.2010706. PMID: 34882041
Staphylococcus aureus Pneumonia in the Community.
He H, Wunderink RG
Semin Respir Crit Care Med 2020 Aug;41(4):470-479. Epub 2020 Jun 10 doi: 10.1055/s-0040-1709992. PMID: 32521547
Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America.
Metlay JP, Waterer GW, Long AC, Anzueto A, Brozek J, Crothers K, Cooley LA, Dean NC, Fine MJ, Flanders SA, Griffin MR, Metersky ML, Musher DM, Restrepo MI, Whitney CG
Am J Respir Crit Care Med 2019 Oct 1;200(7):e45-e67. doi: 10.1164/rccm.201908-1581ST. PMID: 31573350Free PMC Article
Childhood pneumonia in low-and-middle-income countries: An update.
Marangu D, Zar HJ
Paediatr Respir Rev 2019 Nov;32:3-9. Epub 2019 Jun 26 doi: 10.1016/j.prrv.2019.06.001. PMID: 31422032Free PMC Article
Staphylococcus aureus Community-acquired Pneumonia: Prevalence, Clinical Characteristics, and Outcomes.
Self WH, Wunderink RG, Williams DJ, Zhu Y, Anderson EJ, Balk RA, Fakhran SS, Chappell JD, Casimir G, Courtney DM, Trabue C, Waterer GW, Bramley A, Magill S, Jain S, Edwards KM, Grijalva CG
Clin Infect Dis 2016 Aug 1;63(3):300-9. Epub 2016 May 8 doi: 10.1093/cid/ciw300. PMID: 27161775Free PMC Article

Prognosis

Prognostic factors of severe community-acquired staphylococcal pneumonia in France.
Gillet Y, Tristan A, Rasigade JP, Saadatian-Elahi M, Bouchiat C, Bes M, Dumitrescu O, Leloire M, Dupieux C, Laurent F, Lina G, Etienne J, Vanhems P, Argaud L, Vandenesch F; PVL pneumonia study group
Eur Respir J 2021 Nov;58(5) Epub 2021 Nov 11 doi: 10.1183/13993003.04445-2020. PMID: 33833037Free PMC Article
The Clinical Utility of Methicillin-Resistant Staphylococcus aureus (MRSA) Nasal Screening to Rule Out MRSA Pneumonia: A Diagnostic Meta-analysis With Antimicrobial Stewardship Implications.
Parente DM, Cunha CB, Mylonakis E, Timbrook TT
Clin Infect Dis 2018 Jun 18;67(1):1-7. doi: 10.1093/cid/ciy024. PMID: 29340593
Predictive value of methicillin-resistant Staphylococcus aureus (MRSA) nasal swab PCR assay for MRSA pneumonia.
Dangerfield B, Chung A, Webb B, Seville MT
Antimicrob Agents Chemother 2014;58(2):859-64. Epub 2013 Nov 25 doi: 10.1128/AAC.01805-13. PMID: 24277023Free PMC Article
Nosocomial MRSA pneumonia: data from recent clinical trials.
Karvouniaris M, Makris D, Karabekos D, Zakynthinos E
Rev Recent Clin Trials 2011 Sep;6(3):235-40. doi: 10.2174/157488711796575568. PMID: 21682676
Pleuropulmonary suppurations.
Hartl H
Prog Pediatr Surg 1977;10:257-66. PMID: 325603

Clinical prediction guides

Clinical characteristics and risk factors for mortality in patients with community-acquired staphylococcal pneumonia.
Thabet N, Shindo Y, Okumura J, Sano M, Sakakibara T, Murakami Y, Kobayashi H, Saka H, Kondo M, Hasegawa Y; Central Japan Lung Study Group
Nagoya J Med Sci 2022 May;84(2):247-259. doi: 10.18999/nagjms.84.2.247. PMID: 35967943Free PMC Article
The Clinical Utility of Methicillin-Resistant Staphylococcus aureus (MRSA) Nasal Screening to Rule Out MRSA Pneumonia: A Diagnostic Meta-analysis With Antimicrobial Stewardship Implications.
Parente DM, Cunha CB, Mylonakis E, Timbrook TT
Clin Infect Dis 2018 Jun 18;67(1):1-7. doi: 10.1093/cid/ciy024. PMID: 29340593
Predictive value of methicillin-resistant Staphylococcus aureus (MRSA) nasal swab PCR assay for MRSA pneumonia.
Dangerfield B, Chung A, Webb B, Seville MT
Antimicrob Agents Chemother 2014;58(2):859-64. Epub 2013 Nov 25 doi: 10.1128/AAC.01805-13. PMID: 24277023Free PMC Article
The ZEPHyR study: a randomized comparison of linezolid and vancomycin for MRSA pneumonia.
Chavanet P
Med Mal Infect 2013 Dec;43(11-12):451-5. Epub 2013 Nov 13 doi: 10.1016/j.medmal.2013.09.011. PMID: 24238896
Treatment options for nosocomial pneumonia due to MRSA.
Niederman MS
J Infect 2009 Sep;59 Suppl 1:S25-31. doi: 10.1016/S0163-4453(09)60005-0. PMID: 19766886

Recent systematic reviews

Accuracy of Molecular Amplification Assays for Diagnosis of Staphylococcal Pneumonia: a Systematic Review and Meta-analysis.
Chen K, Ahmed S, Sun C, Sheng YJ, Wu G, Deng CL, Ojha SC
J Clin Microbiol 2021 Jul 19;59(8):e0300320. doi: 10.1128/JCM.03003-20. PMID: 33568465Free PMC Article
Clinical cure with ceftriaxone versus ceftaroline or ceftobiprole in the treatment of staphylococcal pneumonia: a systematic review and meta-analysis.
Eljaaly K, Wali H, Basilim A, Alharbi A, Asfour HZ
Int J Antimicrob Agents 2019 Aug;54(2):149-153. Epub 2019 Jun 4 doi: 10.1016/j.ijantimicag.2019.05.023. PMID: 31173864
Systematic Review of the Clinical Utility of Methicillin-Resistant Staphylococcus aureus (MRSA) Nasal Screening for MRSA Pneumonia.
Smith MN, Brotherton AL, Lusardi K, Tan CA, Hammond DA
Ann Pharmacother 2019 Jun;53(6):627-638. Epub 2019 Jan 2 doi: 10.1177/1060028018823027. PMID: 30600697
Community-acquired pneumonia caused by methicillin-resistant Staphylococcus aureus in critically-ill patients: systematic review.
Carballo N, De Antonio-Cuscó M, Echeverría-Esnal D, Luque S, Salas E, Grau S
Farm Hosp 2017 Mar 1;41(2):187-203. doi: 10.7399/fh.2017.41.2.10591. PMID: 28236797
Linezolid vs glycopeptide antibiotics for the treatment of suspected methicillin-resistant Staphylococcus aureus nosocomial pneumonia: a meta-analysis of randomized controlled trials.
Walkey AJ, O'Donnell MR, Wiener RS
Chest 2011 May;139(5):1148-1155. Epub 2010 Sep 23 doi: 10.1378/chest.10-1556. PMID: 20864609Free PMC Article

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