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C3 Glomerulopathy with Monoclonal Gammopathy

MedGen UID:
1698554
Concept ID:
C5204122
Disease or Syndrome

Definition

A subset of C3 glomerulopathy in which there is an associated finding of monoclonal gammopathy. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVC3 Glomerulopathy with Monoclonal Gammopathy

Professional guidelines

PubMed

Rovin BH, Caster DJ, Cattran DC, Gibson KL, Hogan JJ, Moeller MJ, Roccatello D, Cheung M, Wheeler DC, Winkelmayer WC, Floege J; Conference Participants
Kidney Int 2019 Feb;95(2):281-295. doi: 10.1016/j.kint.2018.11.008. PMID: 30665569
Leung N, Bridoux F, Batuman V, Chaidos A, Cockwell P, D'Agati VD, Dispenzieri A, Fervenza FC, Fermand JP, Gibbs S, Gillmore JD, Herrera GA, Jaccard A, Jevremovic D, Kastritis E, Kukreti V, Kyle RA, Lachmann HJ, Larsen CP, Ludwig H, Markowitz GS, Merlini G, Mollee P, Picken MM, Rajkumar VS, Royal V, Sanders PW, Sethi S, Venner CP, Voorhees PM, Wechalekar AD, Weiss BM, Nasr SH
Nat Rev Nephrol 2019 Jan;15(1):45-59. doi: 10.1038/s41581-018-0077-4. PMID: 30510265Free PMC Article
Chauvet S, Frémeaux-Bacchi V, Petitprez F, Karras A, Daniel L, Burtey S, Choukroun G, Delmas Y, Guerrot D, François A, Le Quintrec M, Javaugue V, Ribes D, Vrigneaud L, Arnulf B, Goujon JM, Ronco P, Touchard G, Bridoux F
Blood 2017 Mar 16;129(11):1437-1447. Epub 2017 Jan 9 doi: 10.1182/blood-2016-08-737163. PMID: 28069603

Recent clinical studies

Etiology

Chabannes M, Rabant M, El Sissy C, Dragon-Durey MA, Vieira Martins P, Meuleman MS, Karras A, Buob D, Bridoux F, Daugas E, Audard V, Caillard S, Olagne J, Kandel C, Ferlicot S, Philipponnet C, Crepin T, Thervet E, Ducloux D, Frémeaux-Bacchi V, Chauvet S
Am J Kidney Dis 2023 Sep;82(3):279-289. Epub 2023 Apr 14 doi: 10.1053/j.ajkd.2022.12.020. PMID: 37061020
Leung N, Bridoux F, Batuman V, Chaidos A, Cockwell P, D'Agati VD, Dispenzieri A, Fervenza FC, Fermand JP, Gibbs S, Gillmore JD, Herrera GA, Jaccard A, Jevremovic D, Kastritis E, Kukreti V, Kyle RA, Lachmann HJ, Larsen CP, Ludwig H, Markowitz GS, Merlini G, Mollee P, Picken MM, Rajkumar VS, Royal V, Sanders PW, Sethi S, Venner CP, Voorhees PM, Wechalekar AD, Weiss BM, Nasr SH
Nat Rev Nephrol 2019 Jan;15(1):45-59. doi: 10.1038/s41581-018-0077-4. PMID: 30510265Free PMC Article
Tan Y, Zhao MH
Nephrology (Carlton) 2018 Oct;23 Suppl 4:11-15. doi: 10.1111/nep.13461. PMID: 30298653
Leung N, Drosou ME, Nasr SH
Clin J Am Soc Nephrol 2018 Jan 6;13(1):128-139. Epub 2017 Nov 7 doi: 10.2215/CJN.00560117. PMID: 29114004Free PMC Article
Bridoux F, Leung N, Hutchison CA, Touchard G, Sethi S, Fermand JP, Picken MM, Herrera GA, Kastritis E, Merlini G, Roussel M, Fervenza FC, Dispenzieri A, Kyle RA, Nasr SH; International Kidney and Monoclonal Gammopathy Research Group
Kidney Int 2015 Apr;87(4):698-711. Epub 2015 Jan 21 doi: 10.1038/ki.2014.408. PMID: 25607108

Diagnosis

Chabannes M, Rabant M, El Sissy C, Dragon-Durey MA, Vieira Martins P, Meuleman MS, Karras A, Buob D, Bridoux F, Daugas E, Audard V, Caillard S, Olagne J, Kandel C, Ferlicot S, Philipponnet C, Crepin T, Thervet E, Ducloux D, Frémeaux-Bacchi V, Chauvet S
Am J Kidney Dis 2023 Sep;82(3):279-289. Epub 2023 Apr 14 doi: 10.1053/j.ajkd.2022.12.020. PMID: 37061020
Sy-Go JPT, Herrmann SM, Seshan SV
Adv Chronic Kidney Dis 2022 Mar;29(2):86-102.e1. doi: 10.1053/j.ackd.2022.01.004. PMID: 35817530
Leung N, Bridoux F, Batuman V, Chaidos A, Cockwell P, D'Agati VD, Dispenzieri A, Fervenza FC, Fermand JP, Gibbs S, Gillmore JD, Herrera GA, Jaccard A, Jevremovic D, Kastritis E, Kukreti V, Kyle RA, Lachmann HJ, Larsen CP, Ludwig H, Markowitz GS, Merlini G, Mollee P, Picken MM, Rajkumar VS, Royal V, Sanders PW, Sethi S, Venner CP, Voorhees PM, Wechalekar AD, Weiss BM, Nasr SH
Nat Rev Nephrol 2019 Jan;15(1):45-59. doi: 10.1038/s41581-018-0077-4. PMID: 30510265Free PMC Article
Sethi S, Rajkumar SV, D'Agati VD
J Am Soc Nephrol 2018 Jul;29(7):1810-1823. Epub 2018 Apr 27 doi: 10.1681/ASN.2017121319. PMID: 29703839Free PMC Article
Bridoux F, Leung N, Hutchison CA, Touchard G, Sethi S, Fermand JP, Picken MM, Herrera GA, Kastritis E, Merlini G, Roussel M, Fervenza FC, Dispenzieri A, Kyle RA, Nasr SH; International Kidney and Monoclonal Gammopathy Research Group
Kidney Int 2015 Apr;87(4):698-711. Epub 2015 Jan 21 doi: 10.1038/ki.2014.408. PMID: 25607108

Therapy

Ekladious A, Bhandari R, Javaid MM
Intern Med J 2023 Sep;53(9):1712-1715. Epub 2023 Sep 4 doi: 10.1111/imj.16222. PMID: 37665716
Li X, Qi X, Ma Z, Huang W
BMC Nephrol 2022 Nov 30;23(1):382. doi: 10.1186/s12882-022-03005-0. PMID: 36451151Free PMC Article
Heybeli C, Alexander MP, Bentall AJ, Amer H, Buadi FK, Dean PG, Dingli D, Dispenzieri A, El Ters M, Gertz MA, Issa NS, Kapoor P, Kourelis T, Kukla A, Kumar S, Lacy MQ, Lorenz EC, Muchtar E, Murray DL, Nasr SH, Prieto M, Rajkumar SV, Schinstock CA, Stegall MD, Warsame R, Leung N
Am J Kidney Dis 2022 Feb;79(2):202-216. Epub 2021 Jun 24 doi: 10.1053/j.ajkd.2021.04.015. PMID: 34175375Free PMC Article
Zand L, Rajkumar SV, Leung N, Sethi S, El Ters M, Fervenza FC
J Am Soc Nephrol 2021 May 3;32(5):1163-1173. Epub 2021 Mar 8 doi: 10.1681/ASN.2020101541. PMID: 33685975Free PMC Article
Tan Y, Zhao MH
Nephrology (Carlton) 2018 Oct;23 Suppl 4:11-15. doi: 10.1111/nep.13461. PMID: 30298653

Prognosis

Caravaca-Fontán F, Lucientes L, Serra N, Cavero T, Rodado R, Ramos N, Gonzalez F, Shabaka A, Cabello V, Huerta A, Pampa-Saico S, Gutiérrez E, Quintana LF, López-Rubio ME, Draibe J, Alonso Titos J, Fernández-Juárez G, Goicoechea de Jorge E, Praga M
Nephrol Dial Transplant 2022 Oct 19;37(11):2128-2137. doi: 10.1093/ndt/gfab302. PMID: 34677610
Tan Y, Zhao MH
Nephrology (Carlton) 2018 Oct;23 Suppl 4:11-15. doi: 10.1111/nep.13461. PMID: 30298653
Ravindran A, Fervenza FC, Smith RJH, Sethi S
Kidney Int 2018 Jul;94(1):178-186. Epub 2018 May 3 doi: 10.1016/j.kint.2018.01.037. PMID: 29729982Free PMC Article
Sethi S, Rajkumar SV, D'Agati VD
J Am Soc Nephrol 2018 Jul;29(7):1810-1823. Epub 2018 Apr 27 doi: 10.1681/ASN.2017121319. PMID: 29703839Free PMC Article
Leung N, Drosou ME, Nasr SH
Clin J Am Soc Nephrol 2018 Jan 6;13(1):128-139. Epub 2017 Nov 7 doi: 10.2215/CJN.00560117. PMID: 29114004Free PMC Article

Clinical prediction guides

Caravaca-Fontán F, Lucientes L, Serra N, Cavero T, Rodado R, Ramos N, Gonzalez F, Shabaka A, Cabello V, Huerta A, Pampa-Saico S, Gutiérrez E, Quintana LF, López-Rubio ME, Draibe J, Alonso Titos J, Fernández-Juárez G, Goicoechea de Jorge E, Praga M
Nephrol Dial Transplant 2022 Oct 19;37(11):2128-2137. doi: 10.1093/ndt/gfab302. PMID: 34677610
Heybeli C, Alexander MP, Bentall AJ, Amer H, Buadi FK, Dean PG, Dingli D, Dispenzieri A, El Ters M, Gertz MA, Issa NS, Kapoor P, Kourelis T, Kukla A, Kumar S, Lacy MQ, Lorenz EC, Muchtar E, Murray DL, Nasr SH, Prieto M, Rajkumar SV, Schinstock CA, Stegall MD, Warsame R, Leung N
Am J Kidney Dis 2022 Feb;79(2):202-216. Epub 2021 Jun 24 doi: 10.1053/j.ajkd.2021.04.015. PMID: 34175375Free PMC Article
Tewari R, Chatterjee T, Mendonca S, Dogra M, Pramanik SK, Yanamandra U
Saudi J Kidney Dis Transpl 2021 Mar-Apr;32(2):298-306. doi: 10.4103/1319-2442.335440. PMID: 35017322
Philipponnet C, Kemeny JL, Garrouste C, Soubrier M, Heng AE
Clin Nephrol 2017 Jun;87(6):310-315. doi: 10.5414/CN109056. PMID: 28291506
Sumida K, Ubara Y, Hoshino J, Suwabe T, Nakanishi S, Hiramatsu R, Hasegawa E, Hayami N, Yamanouchi M, Sawa N, Takemoto F, Takaichi K, Oohashi K
Clin Nephrol 2010 Dec;74(6):446-56. PMID: 21084048

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