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Immune-complex glomerulonephritis

MedGen UID:
148168
•Concept ID:
C0744421
•
Disease or Syndrome
Synonyms: Immune complex glomerulonephritis; Immune Complex Glomerulonephritis; immune Complex glomerulonephritis; immune-complex glomerulonephritis
SNOMED CT: Immune-complex glomerulonephritis (123752003); Immune complex glomerulonephritis (123752003)
 
Monarch Initiative: MONDO:0003140

Definition

Inflammation of the glomeruli characterized by the accumulation of antibody-antigen immune complexes, resulting in glomerular damage and impaired kidney function. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVImmune-complex glomerulonephritis

Professional guidelines

PubMed

Anti-neutrophil cytoplasmic antibody associated glomerulonephritis complicating treatment with hydralazine.
Santoriello D, Bomback AS, Kudose S, Batal I, Stokes MB, Canetta PA, Radhakrishnan J, Appel GB, D'Agati VD, Markowitz GS
Kidney Int 2021 Aug;100(2):440-446. Epub 2021 Apr 20 doi: 10.1016/j.kint.2021.03.029. PMID: 33857570
Current best practices and guidelines. Assessment and management of complications in infective endocarditis.
Sexton DJ, Spelman D
Cardiol Clin 2003 May;21(2):273-82, vii-viii. doi: 10.1016/s0733-8651(03)00031-6. PMID: 12874898
Current best practices and guidelines. Assessment and management of complications in infective endocarditis.
Sexton DJ, Spelman D
Infect Dis Clin North Am 2002 Jun;16(2):507-21, xii. doi: 10.1016/s0891-5520(01)00011-3. PMID: 12092484

Recent clinical studies

Etiology

Acute glomerulonephritis.
Sethi S, De Vriese AS, Fervenza FC
Lancet 2022 Apr 23;399(10335):1646-1663. doi: 10.1016/S0140-6736(22)00461-5. PMID: 35461559
Non-immunoglobulin A mesangial immune complex glomerulonephritis in kidney transplants.
Giannico GA, Arnold S, Langone A, Schaefer H, Helderman JH, Shaffer D, Fogo AB
Hum Pathol 2015 Oct;46(10):1521-8. Epub 2015 Jun 26 doi: 10.1016/j.humpath.2015.06.012. PMID: 26245687
The pathophysiology of hypertension in systemic lupus erythematosus.
Ryan MJ
Am J Physiol Regul Integr Comp Physiol 2009 Apr;296(4):R1258-67. Epub 2009 Jan 21 doi: 10.1152/ajpregu.90864.2008. PMID: 19158408Free PMC Article
Viral nephropathy.
Lai AS, Lai KN
Nat Clin Pract Nephrol 2006 May;2(5):254-62. doi: 10.1038/ncpneph0166. PMID: 16932438Free PMC Article
Bacterial arthritis.
Ho G Jr
Curr Opin Rheumatol 1992 Aug;4(4):509-15. PMID: 1503874

Diagnosis

Recurrent disease after pediatric renal transplantation.
Nayak A, Ettenger R, Wesseling-Perry K
Pediatr Transplant 2024 May;28(3):e14676. doi: 10.1111/petr.14676. PMID: 38650536
Acute glomerulonephritis.
Sethi S, De Vriese AS, Fervenza FC
Lancet 2022 Apr 23;399(10335):1646-1663. doi: 10.1016/S0140-6736(22)00461-5. PMID: 35461559
IgG4-related kidney disease.
Cornell LD
Semin Diagn Pathol 2012 Nov;29(4):245-50. doi: 10.1053/j.semdp.2012.07.004. PMID: 23068304
Immune complex renal disease and human immunodeficiency virus infection.
Cohen SD, Kimmel PL
Semin Nephrol 2008 Nov;28(6):535-44. doi: 10.1016/j.semnephrol.2008.08.006. PMID: 19013324
Viral nephropathy.
Lai AS, Lai KN
Nat Clin Pract Nephrol 2006 May;2(5):254-62. doi: 10.1038/ncpneph0166. PMID: 16932438Free PMC Article

Therapy

Acute glomerulonephritis.
Sethi S, De Vriese AS, Fervenza FC
Lancet 2022 Apr 23;399(10335):1646-1663. doi: 10.1016/S0140-6736(22)00461-5. PMID: 35461559
Toll-like receptors in lupus nephritis.
Devarapu SK, Anders HJ
J Biomed Sci 2018 Apr 12;25(1):35. doi: 10.1186/s12929-018-0436-2. PMID: 29650017Free PMC Article
Renal effects of immune checkpoint inhibitors.
Izzedine H, Mateus C, Boutros C, Robert C, Rouvier P, Amoura Z, Mathian A
Nephrol Dial Transplant 2017 Jun 1;32(6):936-942. doi: 10.1093/ndt/gfw382. PMID: 28025384
IgG4-related kidney disease.
Cornell LD
Semin Diagn Pathol 2012 Nov;29(4):245-50. doi: 10.1053/j.semdp.2012.07.004. PMID: 23068304
Chemokines in lupus nephritis.
Kulkarni O, Anders HJ
Front Biosci 2008 May 1;13:3312-20. doi: 10.2741/2927. PMID: 18508434

Prognosis

Recurrent disease after pediatric renal transplantation.
Nayak A, Ettenger R, Wesseling-Perry K
Pediatr Transplant 2024 May;28(3):e14676. doi: 10.1111/petr.14676. PMID: 38650536
Current status and issues of C1q nephropathy.
Mii A, Shimizu A, Masuda Y, Fujita E, Aki K, Ishizaki M, Sato S, Griesemer A, Fukuda Y
Clin Exp Nephrol 2009 Aug;13(4):263-274. Epub 2009 Apr 17 doi: 10.1007/s10157-009-0159-5. PMID: 19373520
Immune complex renal disease and human immunodeficiency virus infection.
Cohen SD, Kimmel PL
Semin Nephrol 2008 Nov;28(6):535-44. doi: 10.1016/j.semnephrol.2008.08.006. PMID: 19013324
Viral nephropathy.
Lai AS, Lai KN
Nat Clin Pract Nephrol 2006 May;2(5):254-62. doi: 10.1038/ncpneph0166. PMID: 16932438Free PMC Article
Glomerulonephritis in bacterial endocarditis.
Neugarten J, Baldwin DS
Am J Med 1984 Aug;77(2):297-304. doi: 10.1016/0002-9343(84)90706-x. PMID: 6380288

Clinical prediction guides

Demographic, clinical and laboratory characteristics of rapidly progressive glomerulonephritis in Turkey: Turkish Society of Nephrology-Glomerular Diseases (TSN-GOLD) Working Group.
Aydin Z, Turkmen K, Dede F, Yasar E, Ozturk S, Aydin M, Tatar E, Sahin G, Manga G, Oto O, Sumnu A, Eroglu E, Dincer T, Dursun B, Eren N, Sevinc M, Guzel FB, Yalin S, Kutlay S, Apaydin S, Berktas HB, Kazan S, Dheir H, Bora F, Basturk T, Sahin I
Clin Exp Nephrol 2021 Feb;25(2):173-183. Epub 2020 Oct 11 doi: 10.1007/s10157-020-01978-6. PMID: 33040246
Renal effects of immune checkpoint inhibitors.
Izzedine H, Mateus C, Boutros C, Robert C, Rouvier P, Amoura Z, Mathian A
Nephrol Dial Transplant 2017 Jun 1;32(6):936-942. doi: 10.1093/ndt/gfw382. PMID: 28025384
Non-immunoglobulin A mesangial immune complex glomerulonephritis in kidney transplants.
Giannico GA, Arnold S, Langone A, Schaefer H, Helderman JH, Shaffer D, Fogo AB
Hum Pathol 2015 Oct;46(10):1521-8. Epub 2015 Jun 26 doi: 10.1016/j.humpath.2015.06.012. PMID: 26245687
IgG4-related kidney disease.
Cornell LD
Semin Diagn Pathol 2012 Nov;29(4):245-50. doi: 10.1053/j.semdp.2012.07.004. PMID: 23068304
Glomerulonephritis in bacterial endocarditis.
Neugarten J, Baldwin DS
Am J Med 1984 Aug;77(2):297-304. doi: 10.1016/0002-9343(84)90706-x. PMID: 6380288

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