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Brief tear break-up time

MedGen UID:
1054145
•Concept ID:
CN376581
•
Finding
HPO: HP:6000069

Definition

Tear film break up time (number of seconds that elapse between the last blink and the appearance of the first dry spot in the tear film) below the lower limit of normal. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBrief tear break-up time

Recent clinical studies

Etiology

Passive cigarette smoke exposure and soft contact lens wear.
Ward SK, Dogru M, Wakamatsu T, Ibrahim O, Matsumoto Y, Kojima T, Sato EA, Ogawa J, Schnider C, Negishi K, Tsubota K
Optom Vis Sci 2010 May;87(5):367-72. doi: 10.1097/OPX.0b013e3181d95188. PMID: 20351603

Diagnosis

Sex-related differences and hormonal effects in the Dry Eye Assessment and Management (DREAM) study.
Zhao M, Yu Y, Roy NS, Ying GS, Asbell P, Bunya VY
Br J Ophthalmol 2023 Dec 18;108(1):23-29. doi: 10.1136/bjo-2022-322238. PMID: 36575626Free PMC Article
Determining the Best Management Strategy for Preventing Short-Term Effects of Digital Display Use on Dry Eyes.
Talens-Estarelles C, García-Marqués JV, Cerviño A, García-Lázaro S
Eye Contact Lens 2022 Oct 1;48(10):416-423. Epub 2022 Jun 30 doi: 10.1097/ICL.0000000000000921. PMID: 36155947

Therapy

Sex-related differences and hormonal effects in the Dry Eye Assessment and Management (DREAM) study.
Zhao M, Yu Y, Roy NS, Ying GS, Asbell P, Bunya VY
Br J Ophthalmol 2023 Dec 18;108(1):23-29. doi: 10.1136/bjo-2022-322238. PMID: 36575626Free PMC Article
Ocular benzalkonium chloride exposure: problems and solutions.
Goldstein MH, Silva FQ, Blender N, Tran T, Vantipalli S
Eye (Lond) 2022 Feb;36(2):361-368. Epub 2021 Jul 14 doi: 10.1038/s41433-021-01668-x. PMID: 34262161Free PMC Article
Passive cigarette smoke exposure and soft contact lens wear.
Ward SK, Dogru M, Wakamatsu T, Ibrahim O, Matsumoto Y, Kojima T, Sato EA, Ogawa J, Schnider C, Negishi K, Tsubota K
Optom Vis Sci 2010 May;87(5):367-72. doi: 10.1097/OPX.0b013e3181d95188. PMID: 20351603

Prognosis

Passive cigarette smoke exposure and soft contact lens wear.
Ward SK, Dogru M, Wakamatsu T, Ibrahim O, Matsumoto Y, Kojima T, Sato EA, Ogawa J, Schnider C, Negishi K, Tsubota K
Optom Vis Sci 2010 May;87(5):367-72. doi: 10.1097/OPX.0b013e3181d95188. PMID: 20351603

Clinical prediction guides

Sex-related differences and hormonal effects in the Dry Eye Assessment and Management (DREAM) study.
Zhao M, Yu Y, Roy NS, Ying GS, Asbell P, Bunya VY
Br J Ophthalmol 2023 Dec 18;108(1):23-29. doi: 10.1136/bjo-2022-322238. PMID: 36575626Free PMC Article
Determining the Best Management Strategy for Preventing Short-Term Effects of Digital Display Use on Dry Eyes.
Talens-Estarelles C, García-Marqués JV, Cerviño A, García-Lázaro S
Eye Contact Lens 2022 Oct 1;48(10):416-423. Epub 2022 Jun 30 doi: 10.1097/ICL.0000000000000921. PMID: 36155947
Ocular benzalkonium chloride exposure: problems and solutions.
Goldstein MH, Silva FQ, Blender N, Tran T, Vantipalli S
Eye (Lond) 2022 Feb;36(2):361-368. Epub 2021 Jul 14 doi: 10.1038/s41433-021-01668-x. PMID: 34262161Free PMC Article
Passive cigarette smoke exposure and soft contact lens wear.
Ward SK, Dogru M, Wakamatsu T, Ibrahim O, Matsumoto Y, Kojima T, Sato EA, Ogawa J, Schnider C, Negishi K, Tsubota K
Optom Vis Sci 2010 May;87(5):367-72. doi: 10.1097/OPX.0b013e3181d95188. PMID: 20351603
Tear cytokine and ocular surface alterations following brief passive cigarette smoke exposure.
Rummenie VT, Matsumoto Y, Dogru M, Wang Y, Hu Y, Ward SK, Igarashi A, Wakamatsu T, Ibrahim O, Goto E, Luyten G, Inoue H, Saito I, Shimazaki J, Tsubota K
Cytokine 2008 Aug;43(2):200-8. Epub 2008 Jul 3 doi: 10.1016/j.cyto.2008.05.011. PMID: 18602273

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