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GTR Home > Conditions/Phenotypes > Primary failure of tooth eruption

Primary failure of tooth eruption

Synonyms
DENTAL NONERUPTION; POSTERIOR OPENBITE MALOCCLUSION, FAMILIAL; PRIMARY RETENTION OF TEETH; UNERUPTED SECOND PRIMARY MOLAR
Modes of inheritance
Autosomal dominant inheritance (Orphanet)

Summary

Primary failure of tooth eruption (PFE) is an autosomal dominant disorder in which nonankylosed posterior teeth fail to move along the eruption path cleared for them, resulting in a posterior open bite. Failure of affected teeth to respond to orthodontic force is a key characteristic (summary by Frazier-Bowers et al., 2007). See also 157950 and 273050 for phenotypes with shared features of PFE. [from OMIM]

Available tests

26 tests are in the database for this condition.

Check Related conditions for additional relevant tests.

Clinical tests (26 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

  • Also known as: EKNS, PFE, PTHR, PTHR1, PTH1R
    Summary: parathyroid hormone 1 receptor

Clinical features

Help
Imported from Human Phenotype Ontology (HPO)

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