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    MATN1-AS1 MATN1 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 100129196, updated on 10-Oct-2023

    Summary

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    Official Symbol
    MATN1-AS1provided by HGNC
    Official Full Name
    MATN1 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:40364
    See related
    Ensembl:ENSG00000186056 AllianceGenome:HGNC:40364
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Ubiquitous expression in ovary (RPKM 1.7), spleen (RPKM 1.5) and 25 other tissues See more
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    Genomic context

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    See MATN1-AS1 in Genome Data Viewer
    Location:
    1p35.2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (30718772..30726746)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (30568743..30576717)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (31191619..31199593)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378618 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:30730647-30731414 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:30805338-30806023 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:30815051-30815718 Neighboring gene MPRA-validated peak152 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:30885131-30885632 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:30885633-30886132 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:31000145-31001344 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_6672 Neighboring gene MPRA-validated peak154 silencer Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_6678 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr1:31090817-31092016 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:31114430-31114930 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:31122410-31123100 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:31134880-31135811 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:31136257-31136758 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 614 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:31180709-31181209 Neighboring gene uncharacterized LOC124903888 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 558 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 559 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 615 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:31191909-31192484 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 616 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 617 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:31205119-31205624 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:31205625-31206130 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:31206171-31206672 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:31212057-31212616 Neighboring gene uncharacterized LOC105378620 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 618 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 619 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 620 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 621 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 622 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 623 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 624 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 625 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:31223351-31223894 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:31223895-31224436 Neighboring gene matrilin 1 Neighboring gene lysosomal protein transmembrane 5 Neighboring gene microRNA 4420

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. LncRNA MATN1-AS1 for Prediction of Prognosis in Osteosarcoma Patients and Its Cellular Function. Liu Y, et al. Mol Biotechnol, 2022 Jan. PMID 34542816
    2. LncRNA MATN1-AS1 prevents glioblastoma cell from proliferation and invasion via RELA regulation and MAPK signaling pathway. Han N, et al. Ann Transl Med, 2019 Dec. PMID 32042800, Free PMC Article
    3. MATN1-AS1 promotes glioma progression by functioning as ceRNA of miR-200b/c/429 to regulate CHD1 expression. Zhu J, et al. Cell Prolif, 2020 Jan. PMID 31667976, Free PMC Article
    4. SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity. Shi P, et al. J Immunol, 2020 Jul 1. PMID 32393512
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Clinical significance of MATN1-AS1 as ceRNA of Mir-200b in tissues and serum of patients with cervical cancer.
      Title: Clinical significance of MATN1-AS1 as ceRNA of Mir-200b in tissues and serum of patients with cervical cancer.
    2. LncRNA MATN1-AS1 for Prediction of Prognosis in Osteosarcoma Patients and Its Cellular Function.
      Title: LncRNA MATN1-AS1 for Prediction of Prognosis in Osteosarcoma Patients and Its Cellular Function.
    3. MATN1-AS1 promotes glioma progression through regulating miR-200b/c/429-CHD1 axis, suggesting MATN1-AS1 as a probable target for glioma treatment.
      Title: MATN1-AS1 promotes glioma progression by functioning as ceRNA of miR-200b/c/429 to regulate CHD1 expression.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • MATN1 antisense RNA 1 (non-protein coding)

    Clone Names

    • FLJ46197

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_034182.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL137857, BC044253
      Related
      ENST00000454613.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      30718772..30726746
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      30568743..30576717
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials