U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CDK11B cyclin dependent kinase 11B [ Homo sapiens (human) ]

Gene ID: 984, updated on 7-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
CDK11Bprovided by HGNC
Official Full Name
cyclin dependent kinase 11Bprovided by HGNC
Primary source
HGNC:HGNC:1729
See related
Ensembl:ENSG00000248333 MIM:176873; AllianceGenome:HGNC:1729
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
p58; PK58; CDK11; CLK-1; CDC2L1; PITSLREA; p58CLK-1; CDK11-p46; CDK11-p58; p58CDC2L1; CDK11-p110
Summary
This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Expression
Ubiquitous expression in testis (RPKM 20.1), bone marrow (RPKM 18.4) and 25 other tissues See more
Orthologs
mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CDK11B in Genome Data Viewer
Location:
1p36.33
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (1635225..1659004, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (1069728..1093685, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (1570603..1590465, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene MIB E3 ubiquitin protein ligase 2 Neighboring gene uncharacterized LOC124903821 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:1565596-1566158 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:1568259-1569070 Neighboring gene matrix metallopeptidase 23B Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:1590308-1591030 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 30 Neighboring gene solute carrier family 35 member E2B Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:1601211-1601711 Neighboring gene ribosomal protein S7 pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 31 Neighboring gene Sharpr-MPRA regulatory region 10763 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:1618619-1618776 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:1619919-1620419 Neighboring gene Sharpr-MPRA regulatory region 15043 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 88 Neighboring gene matrix metallopeptidase 23A (pseudogene)

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Therapeutic potential of CDK11 in cancer. Blazek D. Clin Transl Med, 2023 Mar. PMID 36855776, Free PMC Article
  2. CDK11 is required for transcription of replication-dependent histone genes. Gajdušková P, et al. Nat Struct Mol Biol, 2020 May. PMID 32367068, Free PMC Article
  3. A cyclin-dependent kinase, CDK11/p58, represses cap-dependent translation during mitosis. An S, et al. Cell Mol Life Sci, 2020 Nov. PMID 32030451, Free PMC Article
  4. DNA methylation of the CDC2L1 gene promoter region decreases the expression of the CDK11p58 protein and reduces apoptosis in keloid fibroblasts. Zhang G, et al. Arch Dermatol Res, 2018 Mar. PMID 29204684
  5. Cyclin-Dependent Kinase 11 (CDK11) Is Required for Ovarian Cancer Cell Growth In Vitro and In Vivo, and Its Inhibition Causes Apoptosis and Sensitizes Cells to Paclitaxel. Liu X, et al. Mol Cancer Ther, 2016 Jul. PMID 27207777, Free PMC Article

See all (124) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. CDK11 facilitates centromeric transcription to maintain centromeric cohesion during mitosis.
    Title: CDK11 facilitates centromeric transcription to maintain centromeric cohesion during mitosis.
  2. CDK10, CDK11, FOXO1, and FOXO3 Gene Expression in Alzheimer's Disease Encephalic Samples.
    Title: CDK10, CDK11, FOXO1, and FOXO3 Gene Expression in Alzheimer's Disease Encephalic Samples.
  3. Therapeutic potential of CDK11 in cancer.
    Title: Therapeutic potential of CDK11 in cancer.
  4. CDK11 negatively regulates Wnt/beta-catenin signaling in the endosomal compartment by affecting microtubule stability.
    Title: CDK11 negatively regulates Wnt/β-catenin signaling in the endosomal compartment by affecting microtubule stability.
  5. A cyclin-dependent kinase, CDK11/p58, represses cap-dependent translation during mitosis.
    Title: A cyclin-dependent kinase, CDK11/p58, represses cap-dependent translation during mitosis.
  6. CDK11 is required for transcription of replication-dependent histone genes.
    Title: CDK11 is required for transcription of replication-dependent histone genes.
  7. Transcriptional activation of CBFbeta by CDK11(p110) is necessary to promote osteosarcoma cell proliferation
    Title: Transcriptional activation of CBFβ by CDK11(p110) is necessary to promote osteosarcoma cell proliferation.
  8. These results provided evidence that CDK11(p110) play a critical role in the tumorigenicity of esophageal squamous cell carcinoma cells, which suggests that CDK11(p110) may be a promising therapeutic target in esophageal squamous cell carcinoma.
    Title: CDK11(p110) plays a critical role in the tumorigenicity of esophageal squamous cell carcinoma cells and is a potential drug target.
  9. These findings suggest that CDK11 is involved in the regulation of AR pathway and AR can be a potential novel prognostic marker and therapeutic target for osteosarcoma treatment.
    Title: Androgen receptor is a potential novel prognostic marker and oncogenic target in osteosarcoma with dependence on CDK11.
  10. DNA methylation exists in the CDC2L1 gene promoter region in keloid tissue fibroblasts. DNA methylation of the CDC2L1 gene promoter region dramatically inhibits the expression of CDK11p58 protein in keloid tissues.
    Title: DNA methylation of the CDC2L1 gene promoter region decreases the expression of the CDK11p58 protein and reduces apoptosis in keloid fibroblasts.
Submit: New GeneRIF Correction See all GeneRIFs (36)

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

HIV-1 interactions

Go to the top of the page Help

Protein interactions

Protein Gene Interaction Pubs
Tat tat CDK11 depletion reduces protein expression of CDK9 and HEXIM1 and Tat transactivation of HIV-1 provirus PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • FLJ59152

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA binding HDA PubMed 
enables cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase activity TAS
Traceable Author Statement
more info
 PubMed 
enables protein serine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in apoptotic process NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in mitotic cell cycle NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein phosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of DNA-templated transcription NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in regulation of cell growth IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in regulation of mRNA processing IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
cyclin-dependent kinase 11B
Names
CDC-related protein kinase p58
PITSLRE serine/threonine-protein kinase CDC2L1
cell division cycle 2-like 1 (PITSLRE proteins)
cell division protein kinase 11B
galactosyltransferase-associated protein kinase p58/GTA
p58 CLK-1
NP_001278274.1
NP_001778.2
NP_277021.2
NP_277022.1
NP_277024.2
NP_277025.1
XP_006711128.1
XP_011540792.1
XP_011540793.1
XP_011540794.1
XP_011540795.1
XP_011540796.1
XP_016858414.1
XP_016858415.1
XP_016858417.1
XP_024306958.1
XP_047291284.1
XP_047291286.1
XP_047291311.1
XP_047291316.1
XP_047291317.1
XP_047291318.1
XP_047291319.1
XP_047291323.1
XP_047291324.1
XP_047291325.1
XP_047291327.1
XP_054195777.1
XP_054195778.1
XP_054195779.1
XP_054195780.1
XP_054195781.1
XP_054195782.1
XP_054195783.1
XP_054195784.1
XP_054195785.1
XP_054195786.1
XP_054195787.1
XP_054195788.1
XP_054195789.1
XP_054195790.1
XP_054195791.1
XP_054195792.1
XP_054195793.1
XP_054195794.1
XP_054195795.1
XP_054195796.1
XP_054195797.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001291345.2 → NP_001278274.1  cyclin-dependent kinase 11B isoform 10

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) uses two alternate splice sites in the central coding region, compared to variant 1. The encoded isoform (10) is shorter, compared to isoform 1.
    Source sequence(s)
    AA778148, AK000081, BC140714, DB516340, DC295949, DC362247, FO704657
    UniProtKB/TrEMBL
    B4E3D9
    Conserved Domains (2) summary
    cd07843
    Location:409 → 700
    STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1
    PLN00009
    Location:412 → 702
    PLN00009; cyclin-dependent kinase A; Provisional

  2. NM_001787.3 → NP_001778.2  cyclin-dependent kinase 11B isoform 1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AA778148, AK000081, BC140714, DB516340, DC362247, FO704657
    Consensus CDS
    CCDS72683.1
    UniProtKB/Swiss-Prot
    B7ZVY7, J3KTL7, J3QR29, J3QR44, O95265, P21127, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59
    UniProtKB/TrEMBL
    B4E3D9
    Related
    ENSP00000464036.2, ENST00000407249.7
    Conserved Domains (1) summary
    cd07843
    Location:432 → 723
    STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1

  3. NM_033486.3 → NP_277021.2  cyclin-dependent kinase 11B isoform 2

    See identical proteins and their annotated locations for NP_277021.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the central coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.
    Source sequence(s)
    AA778148, AK000081, BC140714, DB516340, DC362247, FO704657
    Consensus CDS
    CCDS72684.1
    UniProtKB/TrEMBL
    B4E3D9
    Related
    ENSP00000463048.2, ENST00000341832.11
    Conserved Domains (2) summary
    cd07843
    Location:419 → 710
    STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1
    PLN00009
    Location:422 → 712
    PLN00009; cyclin-dependent kinase A; Provisional

  4. NM_033487.3 → NP_277022.1  cyclin-dependent kinase 11B isoform 3

    See identical proteins and their annotated locations for NP_277022.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in its 5' UTR and uses a downstream start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AA778148, AK000081, BC140714, DB516340, DC362247, FO704657
    UniProtKB/TrEMBL
    A4VCI5
    Conserved Domains (2) summary
    cd07843
    Location:163 → 454
    STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1
    PLN00009
    Location:166 → 456
    PLN00009; cyclin-dependent kinase A; Provisional

  5. NM_033489.3 → NP_277024.2  cyclin-dependent kinase 11B isoform 5

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in its 5' UTR and 5' coding region, and uses an alternate splice site in the central coding region, compared to variant 1. The encoded isoform (5) is shorter and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AA778148, AK000081, AK295607, BC140714, DB516340, DC362247, FO704657
    Consensus CDS
    CCDS72682.1
    UniProtKB/TrEMBL
    Q5QPR4
    Related
    ENSP00000464016.2, ENST00000340677.9
    Conserved Domains (2) summary
    cd07843
    Location:385 → 676
    STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1
    PLN00009
    Location:388 → 678
    PLN00009; cyclin-dependent kinase A; Provisional

  6. NM_033490.3 → NP_277025.1  cyclin-dependent kinase 11B isoform 6

    See identical proteins and their annotated locations for NP_277025.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) differs in its 5' UTR, uses a downstream start codon, and uses an alternate splice site in its 5' coding region, compared to variant 1. The encoded isoform (6) is shorter, compared to isoform 1.
    Source sequence(s)
    AA778148, AK000081, BC140714, DB516340, DC362247, FO704657
    UniProtKB/TrEMBL
    A4VCI5
    Conserved Domains (2) summary
    cd07843
    Location:202 → 493
    STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1
    PLN00009
    Location:205 → 495
    PLN00009; cyclin-dependent kinase A; Provisional

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    1635225..1659004 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006711065.5 → XP_006711128.1  cyclin-dependent kinase 11B isoform X5

    UniProtKB/TrEMBL
    B4E3D9
    Conserved Domains (2) summary
    cd07843
    Location:422 → 713
    STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1
    PLN00009
    Location:425 → 715
    PLN00009; cyclin-dependent kinase A; Provisional

  2. XM_017002926.3 → XP_016858415.1  cyclin-dependent kinase 11B isoform X6

    UniProtKB/TrEMBL
    B4E3D9
    Related
    ENSP00000485705.1, ENST00000626918.2

  3. XM_011542493.4 → XP_011540795.1  cyclin-dependent kinase 11B isoform X3

    UniProtKB/TrEMBL
    B4E3D9
    Conserved Domains (2) summary
    cd07843
    Location:431 → 722
    STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1
    PLN00009
    Location:434 → 724
    PLN00009; cyclin-dependent kinase A; Provisional

  4. XM_017002925.3 → XP_016858414.1  cyclin-dependent kinase 11B isoform X4

    UniProtKB/TrEMBL
    B4E3D9

  5. XM_011542490.4 → XP_011540792.1  cyclin-dependent kinase 11B isoform X1

    See identical proteins and their annotated locations for XP_011540792.1

    UniProtKB/TrEMBL
    B4E3D9
    Conserved Domains (2) summary
    cd07843
    Location:441 → 732
    STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1
    PLN00009
    Location:444 → 734
    PLN00009; cyclin-dependent kinase A; Provisional

  6. XM_047435361.1 → XP_047291317.1  cyclin-dependent kinase 11B isoform X11

  7. XM_047435330.1 → XP_047291286.1  cyclin-dependent kinase 11B isoform X2

    UniProtKB/Swiss-Prot
    B7ZVY7, J3KTL7, J3QR29, J3QR44, O95265, P21127, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59

  8. XM_011542492.3 → XP_011540794.1  cyclin-dependent kinase 11B isoform X1

    See identical proteins and their annotated locations for XP_011540794.1

    UniProtKB/TrEMBL
    B4E3D9
    Conserved Domains (2) summary
    cd07843
    Location:441 → 732
    STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1
    PLN00009
    Location:444 → 734
    PLN00009; cyclin-dependent kinase A; Provisional

  9. XM_047435328.1 → XP_047291284.1  cyclin-dependent kinase 11B isoform X2

    UniProtKB/Swiss-Prot
    B7ZVY7, J3KTL7, J3QR29, J3QR44, O95265, P21127, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59

  10. XM_011542491.3 → XP_011540793.1  cyclin-dependent kinase 11B isoform X1

    See identical proteins and their annotated locations for XP_011540793.1

    UniProtKB/TrEMBL
    B4E3D9
    Conserved Domains (2) summary
    cd07843
    Location:441 → 732
    STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1
    PLN00009
    Location:444 → 734
    PLN00009; cyclin-dependent kinase A; Provisional

  11. XM_047435362.1 → XP_047291318.1  cyclin-dependent kinase 11B isoform X12

  12. XM_047435360.1 → XP_047291316.1  cyclin-dependent kinase 11B isoform X10

  13. XM_047435355.1 → XP_047291311.1  cyclin-dependent kinase 11B isoform X9

  14. XM_017002928.3 → XP_016858417.1  cyclin-dependent kinase 11B isoform X8

    UniProtKB/TrEMBL
    Q5QPR4

  15. XM_011542494.4 → XP_011540796.1  cyclin-dependent kinase 11B isoform X7

    UniProtKB/TrEMBL
    Q5QPR4
    Conserved Domains (1) summary
    cd07843
    Location:407 → 698
    STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1

  16. XM_047435367.1 → XP_047291323.1  cyclin-dependent kinase 11B isoform X14

  17. XM_024451190.2 → XP_024306958.1  cyclin-dependent kinase 11B isoform X18

    UniProtKB/TrEMBL
    Q96CA8
    Conserved Domains (1) summary
    cd07843
    Location:34 → 325
    STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1

  18. XM_047435363.1 → XP_047291319.1  cyclin-dependent kinase 11B isoform X13

  19. XM_047435371.1 → XP_047291327.1  cyclin-dependent kinase 11B isoform X17

  20. XM_047435369.1 → XP_047291325.1  cyclin-dependent kinase 11B isoform X16

  21. XM_047435368.1 → XP_047291324.1  cyclin-dependent kinase 11B isoform X15

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    1069728..1093685 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054339805.1 → XP_054195780.1  cyclin-dependent kinase 11B isoform X2

    UniProtKB/Swiss-Prot
    B7ZVY7, J3KTL7, J3QR29, J3QR44, O95265, P21127, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59

  2. XM_054339809.1 → XP_054195784.1  cyclin-dependent kinase 11B isoform X5

  3. XM_054339810.1 → XP_054195785.1  cyclin-dependent kinase 11B isoform X6

  4. XM_054339807.1 → XP_054195782.1  cyclin-dependent kinase 11B isoform X3

  5. XM_054339808.1 → XP_054195783.1  cyclin-dependent kinase 11B isoform X4

  6. XM_054339802.1 → XP_054195777.1  cyclin-dependent kinase 11B isoform X1

  7. XM_054339804.1 → XP_054195779.1  cyclin-dependent kinase 11B isoform X1

  8. XM_054339803.1 → XP_054195778.1  cyclin-dependent kinase 11B isoform X1

  9. XM_054339815.1 → XP_054195790.1  cyclin-dependent kinase 11B isoform X11

  10. XM_054339806.1 → XP_054195781.1  cyclin-dependent kinase 11B isoform X2

    UniProtKB/Swiss-Prot
    B7ZVY7, J3KTL7, J3QR29, J3QR44, O95265, P21127, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59

  11. XM_054339816.1 → XP_054195791.1  cyclin-dependent kinase 11B isoform X12

  12. XM_054339814.1 → XP_054195789.1  cyclin-dependent kinase 11B isoform X10

  13. XM_054339813.1 → XP_054195788.1  cyclin-dependent kinase 11B isoform X9

  14. XM_054339812.1 → XP_054195787.1  cyclin-dependent kinase 11B isoform X8

  15. XM_054339811.1 → XP_054195786.1  cyclin-dependent kinase 11B isoform X7

  16. XM_054339818.1 → XP_054195793.1  cyclin-dependent kinase 11B isoform X14

  17. XM_054339822.1 → XP_054195797.1  cyclin-dependent kinase 11B isoform X18

  18. XM_054339817.1 → XP_054195792.1  cyclin-dependent kinase 11B isoform X13

  19. XM_054339821.1 → XP_054195796.1  cyclin-dependent kinase 11B isoform X17

  20. XM_054339820.1 → XP_054195795.1  cyclin-dependent kinase 11B isoform X16

  21. XM_054339819.1 → XP_054195794.1  cyclin-dependent kinase 11B isoform X15

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_033488.1: Suppressed sequence

    Description
    NM_033488.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.

  2. NM_033492.1: Suppressed sequence

    Description
    NM_033492.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.

  3. NM_033493.1: Suppressed sequence

    Description
    NM_033493.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P21127.4 GenPept UniProtKB/Swiss-Prot:P21127

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Miscellaneous