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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_011878.1 RefSeqGene
- Range
-
5405..1119034
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001135659.3 → NP_001129131.1 neurexin-1 isoform alpha2 precursor
See identical proteins and their annotated locations for NP_001129131.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (alpha2) results from the use of the 5'-most promoter, referred to as alpha. It represents the longest transcript that encodes the longest isoform (alpha2) of the representative RefSeq variants. This isoform contains EGF-like, several laminin G, and syndecan domains.
- Source sequence(s)
-
AC007462, AC007682, AC009234, AC068725, AC069550, AC078994
- Consensus CDS
-
CCDS46282.1
- UniProtKB/TrEMBL
-
A0A0R4J2G7
- Related
- ENSP00000385142.1, ENST00000404971.5
- Conserved Domains (6) summary
-
- smart00294
Location:1492 → 1510
- 4.1m; putative band 4.1 homologues' binding motif
- smart00282
Location:543 → 692
- LamG; Laminin G domain
- cd00054
Location:720 → 753
- EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
- cd00110
Location:30 → 190
- LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
- pfam01034
Location:1472 → 1511
- Syndecan; Syndecan domain
- pfam02210
Location:973 → 1101
- Laminin_G_2; Laminin G domain
-
NM_001320156.4 → NP_001307085.1 neurexin-1 isoform gamma1
Status: REVIEWED
- Description
- Transcript Variant: This variant (gamma1) results from the use of an alternate promoter, referred to as gamma. It contains an alternate 5' terminal exon and lacks all the exons, except the last two 3' terminal exons, compared to variant alpha2. Hence, the encoded isoform (gamma1) is considerably shorter with a distinct N-terminus lacking the EGF-like and laminin G domains, and containing only the syndecan domain compared to isoform alpha2.
- Source sequence(s)
-
AC078994
- Consensus CDS
-
CCDS82444.1
- UniProtKB/TrEMBL
- A0A1B0GTL0, H7BYC7
- Related
- ENSP00000367510.4, ENST00000378262.7
- Conserved Domains (2) summary
-
- smart00294
Location:87 → 105
- 4.1m; putative band 4.1 homologues' binding motif
- pfam01034
Location:67 → 106
- Syndecan; Syndecan domain
-
NM_001320157.4 → NP_001307086.1 neurexin-1 isoform gamma2
Status: REVIEWED
- Description
- Transcript Variant: This variant (gamma2) results from the use of an alternate promoter, referred to as gamma. It contains an alternate 5' terminal exon and lacks all the exons, except the last two 3' terminal exons (the penultimate exon uses an alternate in-frame donor splice site), compared to variant alpha2. Hence, the encoded isoform (gamma2) is considerably shorter with a distinct N-terminus lacking the EGF-like and laminin G domains, and containing only the syndecan domain compared to isoform alpha2.
- Source sequence(s)
-
AC078994
- Consensus CDS
-
CCDS82445.1
- UniProtKB/TrEMBL
- A0A1B0GTL0, H0Y568
- Related
- ENSP00000396738.2, ENST00000412315.5
- Conserved Domains (2) summary
-
- smart00294
Location:84 → 102
- 4.1m; putative band 4.1 homologues' binding motif
- pfam01034
Location:64 → 103
- Syndecan; Syndecan domain
-
NM_001330077.2 → NP_001317006.1 neurexin-1 isoform alpha3 precursor
Status: REVIEWED
- Source sequence(s)
-
AC007462, AC007682, AC009234, AC068725, AC069550, AC078994
- Consensus CDS
-
CCDS82449.1
- UniProtKB/TrEMBL
- A0A0R4J2G7, A0A1D5RMU6
- Related
- ENSP00000486879.1, ENST00000630543.2
- Conserved Domains (6) summary
-
- smart00294
Location:1444 → 1462
- 4.1m; putative band 4.1 homologues' binding motif
- smart00282
Location:495 → 644
- LamG; Laminin G domain
- cd00054
Location:672 → 705
- EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
- cd00110
Location:30 → 190
- LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
- pfam01034
Location:1424 → 1463
- Syndecan; Syndecan domain
- pfam02210
Location:925 → 1053
- Laminin_G_2; Laminin G domain
-
NM_001330078.2 → NP_001317007.1 neurexin-1 isoform alpha4 precursor
Status: REVIEWED
- Source sequence(s)
-
AC007462, AC007682, AC009234, AC068725, AC069550, AC078994
- Consensus CDS
-
CCDS82451.1
- UniProtKB/TrEMBL
- A0A0R4J2G7, E7ERL8
- Related
- ENSP00000385017.2, ENST00000401669.7
- Conserved Domains (6) summary
-
- smart00294
Location:1452 → 1470
- 4.1m; putative band 4.1 homologues' binding motif
- smart00282
Location:503 → 652
- LamG; Laminin G domain
- cd00054
Location:680 → 713
- EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
- cd00110
Location:30 → 190
- LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
- pfam01034
Location:1432 → 1471
- Syndecan; Syndecan domain
- pfam02210
Location:933 → 1061
- Laminin_G_2; Laminin G domain
-
NM_001330079.2 → NP_001317008.1 neurexin-1 isoform 6 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) lacks multiple 3' coding exons and contains an alternate 3' terminal exon compared to variant alpha2. The encoded isoform (6) is much shorter than isoform alpha2.
- Source sequence(s)
-
AC007682
- Consensus CDS
-
CCDS86838.1
- UniProtKB/TrEMBL
- A0A0D9SEQ7, Q49A31
- Related
- ENSP00000485912.1, ENST00000626899.1
- Conserved Domains (1) summary
-
- cd00110
Location:30 → 190
- LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
-
NM_001330081.2 → NP_001317010.1 neurexin-1 isoform 7 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) lacks multiple 3' coding exons and contains an alternate 3' terminal exon compared to variant alpha2. The encoded isoform (7) is much shorter than isoform alpha2.
- Source sequence(s)
-
AC007682
- Consensus CDS
-
CCDS86840.1
- UniProtKB/TrEMBL
- E7EQN4, Q49A31
- Related
- ENSP00000385310.1, ENST00000405581.3
- Conserved Domains (1) summary
-
- cd00110
Location:30 → 190
- LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
-
NM_001330082.2 → NP_001317011.1 neurexin-1 isoform alpha5 precursor
Status: REVIEWED
- Source sequence(s)
-
AC007462, AC007682, AC009234, AC068725, AC069550, AC078994
- Consensus CDS
-
CCDS82450.1
- UniProtKB/TrEMBL
-
A0A0R4J2G7
- Related
- ENSP00000485887.1, ENST00000625672.2
- Conserved Domains (6) summary
-
- smart00294
Location:1441 → 1459
- 4.1m; putative band 4.1 homologues' binding motif
- smart00282
Location:495 → 644
- LamG; Laminin G domain
- cd00054
Location:672 → 705
- EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
- cd00110
Location:30 → 190
- LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
- pfam01034
Location:1421 → 1460
- Syndecan; Syndecan domain
- pfam02210
Location:925 → 1053
- Laminin_G_2; Laminin G domain
-
NM_001330083.2 → NP_001317012.1 neurexin-1 isoform alpha6 precursor
Status: REVIEWED
- Source sequence(s)
-
AC007462, AC007682, AC009234, AC068725, AC069550, AC078994
- UniProtKB/TrEMBL
-
A0A0R4J2G7
-
NM_001330084.2 → NP_001317013.1 neurexin-1 isoform alpha7 precursor
Status: REVIEWED
- Source sequence(s)
-
AC007462, AC007682, AC009234, AC068725, AC069550, AC078994
- UniProtKB/TrEMBL
-
A0A0R4J2G7
-
NM_001330085.2 → NP_001317014.1 neurexin-1 isoform alpha8 precursor
Status: REVIEWED
- Source sequence(s)
-
AC007462, AC007682, AC009234, AC068725, AC069550, AC078994
- UniProtKB/TrEMBL
-
A0A0R4J2G7
-
NM_001330086.2 → NP_001317015.1 neurexin-1 isoform alpha9 precursor
Status: REVIEWED
- Source sequence(s)
-
AC007462, AC007682, AC009234, AC068725, AC069550, AC078994
- UniProtKB/TrEMBL
-
A0A0R4J2G7
-
NM_001330087.2 → NP_001317016.1 neurexin-1 isoform alpha10 precursor
Status: REVIEWED
- Source sequence(s)
-
AC007462, AC007682, AC009234, AC068725, AC069550, AC078994
- UniProtKB/TrEMBL
-
A0A0R4J2G7
-
NM_001330088.2 → NP_001317017.1 neurexin-1 isoform alpha11 precursor
Status: REVIEWED
- Source sequence(s)
-
AC007462, AC007682, AC009234, AC068725, AC069550, AC078994
- UniProtKB/TrEMBL
-
A0A0R4J2G7
-
NM_001330089.2 → NP_001317018.1 neurexin-1 isoform 8 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (8) lacks multiple 3' coding exons and contains an alternate 3' exon structure compared to variant alpha2. The encoded isoform (8) is much shorter than isoform alpha2 and has a distinct C-terminus.
- Source sequence(s)
-
AC007682, BX113737
- UniProtKB/TrEMBL
-
Q49A31
- Conserved Domains (1) summary
-
- cd00110
Location:30 → 190
- LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
-
NM_001330090.2 → NP_001317019.1 neurexin-1 isoform 9 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (9) lacks multiple 3' coding exons and contains an alternate 3' terminal exon compared to variant alpha2. The encoded isoform (9) is much shorter than isoform alpha2 and has a distinct C-terminus.
- Source sequence(s)
-
AC007682
- UniProtKB/TrEMBL
-
Q49A31
- Related
- ENSP00000490494.1, ENST00000637511.1
-
NM_001330091.2 → NP_001317020.1 neurexin-1 isoform beta2
Status: REVIEWED
- Source sequence(s)
-
AC068725, AC069550, AC078994
- Consensus CDS
-
CCDS82447.1
- UniProtKB/TrEMBL
-
A0A0D9SEM5
- Related
- ENSP00000485815.1, ENST00000628364.2
-
NM_001330092.2 → NP_001317021.1 neurexin-1 isoform beta3
Status: REVIEWED
- Source sequence(s)
-
AC068725, AC069550, AC078994
- Consensus CDS
-
CCDS82446.1
- UniProtKB/Swiss-Prot
- E7ETA5, P58400
- Related
- ENSP00000385580.2, ENST00000401710.5
- Conserved Domains (3) summary
-
- smart00294
Location:417 → 435
- 4.1m; putative band 4.1 homologues' binding motif
- cd00110
Location:90 → 209
- LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
- pfam01034
Location:397 → 436
- Syndecan; Syndecan domain
-
NM_001330093.2 → NP_001317022.1 neurexin-1 isoform alpha12 precursor
Status: REVIEWED
- Source sequence(s)
-
AC007462, AC007682, AC009234, AC068725, AC069550, AC078994
- UniProtKB/TrEMBL
-
A0A0R4J2G7
-
NM_001330094.2 → NP_001317023.1 neurexin-1 isoform alpha13 precursor
Status: REVIEWED
- Source sequence(s)
-
AC007462, AC007682, AC009234, AC068725, AC069550, AC078994
- UniProtKB/TrEMBL
-
A0A0R4J2G7
-
NM_001330095.2 → NP_001317024.1 neurexin-1 isoform alpha14 precursor
Status: REVIEWED
- Source sequence(s)
-
AC007462, AC007682, AC009234, AC068725, AC069550, AC078994
- UniProtKB/TrEMBL
-
A0A0R4J2G7
-
NM_001330096.2 → NP_001317025.1 neurexin-1 isoform alpha15 precursor
Status: REVIEWED
- Source sequence(s)
-
AC007462, AC007682, AC009234, AC068725, AC069550, AC078994
- UniProtKB/TrEMBL
-
A0A0R4J2G7
-
NM_001330097.2 → NP_001317026.1 neurexin-1 isoform beta4
Status: REVIEWED
- Source sequence(s)
-
AC068725, AC069550, AC078994
- UniProtKB/TrEMBL
-
A4FVB9
-
NM_004801.6 → NP_004792.1 neurexin-1 isoform alpha1 precursor
See identical proteins and their annotated locations for NP_004792.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (alpha1) results from the use of the 5'-most promoter, referred to as alpha. It lacks two in-frame exons and uses an alternate in-frame donor splice site at an internal exon compared to variant alpha2. The resulting isoform (alpha1) is shorter missing a few internal protein segments compared to isoform alpha2. This isoform contains EGF-like, several laminin G, and syndecan domains.
- Source sequence(s)
-
AC007462, AC007682, AC009234, AC068725, AC069550, AC078994
- Consensus CDS
-
CCDS54360.1
- UniProtKB/Swiss-Prot
- A7KRL9, O60323, Q53TJ9, Q53TQ1, Q5HYI0, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6, Q9ULB1
- UniProtKB/TrEMBL
-
A0A0R4J2G7
- Related
- ENSP00000384311.2, ENST00000406316.6
- Conserved Domains (6) summary
-
- smart00294
Location:1422 → 1440
- 4.1m; putative band 4.1 homologues' binding motif
- smart00282
Location:503 → 652
- LamG; Laminin G domain
- cd00054
Location:680 → 713
- EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
- cd00110
Location:30 → 190
- LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
- pfam01034
Location:1402 → 1441
- Syndecan; Syndecan domain
- pfam02210
Location:933 → 1061
- Laminin_G_2; Laminin G domain
-
NM_138735.5 → NP_620072.1 neurexin-1 isoform beta1
See identical proteins and their annotated locations for NP_620072.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (beta1) results from the use of an alternate promoter, referred to as beta. It contains an alternate 5' terminal exon and lacks most of the 5' exons and another exon in the 3' region compared to variant alpha2. The resulting isoform (beta1) is shorter with a distinct N-terminus lacking the EGF-like domain and containing fewer laminin G domains compared to isoform alpha2.
- Source sequence(s)
-
AC068725, AC069550, AC078994
- Consensus CDS
-
CCDS1845.1
- UniProtKB/TrEMBL
-
A4FVB9
- Related
- ENSP00000341184.5, ENST00000342183.9
- Conserved Domains (3) summary
-
- smart00294
Location:387 → 405
- 4.1m; putative band 4.1 homologues' binding motif
- pfam01034
Location:367 → 406
- Syndecan; Syndecan domain
- pfam02210
Location:121 → 239
- Laminin_G_2; Laminin G domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000002.12 Reference GRCh38.p14 Primary Assembly
- Range
-
49918503..51032132 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060926.1 Alternate T2T-CHM13v2.0
- Range
-
49914520..51028290 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)