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MAP7 microtubule associated protein 7 [ Homo sapiens (human) ]

Gene ID: 9053, updated on 3-Apr-2024

Summary

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Official Symbol
MAP7provided by HGNC
Official Full Name
microtubule associated protein 7provided by HGNC
Primary source
HGNC:HGNC:6869
See related
Ensembl:ENSG00000135525 MIM:604108; AllianceGenome:HGNC:6869
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EMAP115; E-MAP-115
Summary
The product of this gene is a microtubule-associated protein that is predominantly expressed in cells of epithelial origin. Microtubule-associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarization and differentiation. This protein has been shown to be able to stabilize microtubules, and may serve to modulate microtubule functions. Studies of the related mouse protein also suggested an essential role in microtubule function required for spermatogenesis. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Expression
Broad expression in kidney (RPKM 10.5), brain (RPKM 10.5) and 21 other tissues See more
Orthologs
mouse all
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Genomic context

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See MAP7 in Genome Data Viewer
Location:
6q23.3
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (136342734..136550422, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (137530867..137738614, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (136663872..136871560, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:136609778-136610374 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr6:136610456-136611655 Neighboring gene uncharacterized LOC124901408 Neighboring gene BCL2 associated transcription factor 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:136655703-136656202 Neighboring gene ribosomal protein lateral stalk subunit P1 pseudogene 8 Neighboring gene MPRA-validated peak6144 silencer Neighboring gene phosphopantothenate--cysteine ligase-like Neighboring gene Sharpr-MPRA regulatory region 12163 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_90180 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_90214 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_90217 Neighboring gene MPRA-validated peak6145 silencer Neighboring gene NADH:ubiquinone oxidoreductase subunit S5 pseudogene 1 Neighboring gene MPRA-validated peak6146 silencer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:136846904-136847714 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:136870396-136870934 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17572 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17573 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:136871473-136872010 Neighboring gene RN7SK pseudogene 299 Neighboring gene MPRA-validated peak6148 silencer Neighboring gene MAP7 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25115 Neighboring gene mitogen-activated protein kinase kinase kinase 5 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr6:136933733-136934303 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr6:136934304-136934873 Neighboring gene MAP3K5 antisense RNA 1 Neighboring gene RNA, 5S ribosomal pseudogene 219

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. MAP7 Promotes Breast Cancer Cell Migration and Invasion by Regulating the NF-B Pathway. Wang R, et al. Ann Clin Lab Sci, 2022 Sep. PMID 36261182
  2. Cloning and characterization of an inversion breakpoint at 6q23.3 suggests a role for Map7 in sacral dysgenesis. Sood R, et al. Cytogenet Genome Res, 2004. PMID 15218243
  3. Expression and distribution of distinct variants of E-MAP-115 during proliferation and differentiation of human intestinal epithelial cells. Vanier MT, et al. Cell Motil Cytoskeleton, 2003 Aug. PMID 12845596
  4. Rapid dynamics of the microtubule binding of ensconsin in vivo. Bulinski JC, et al. J Cell Sci, 2001 Nov. PMID 11719555
  5. Upregulation and redistribution of E-MAP-115 (epithelial microtubule-associated protein of 115 kDa) in terminally differentiating keratinocytes is coincident with the formation of intercellular contacts. Fabre-Jonca N, et al. J Invest Dermatol, 1999 Feb. PMID 9989799

See all (83) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A structural and dynamic visualization of the interaction between MAP7 and microtubules.
    Title: A structural and dynamic visualization of the interaction between MAP7 and microtubules.
  2. MAP7 Promotes Breast Cancer Cell Migration and Invasion by Regulating the NF-B Pathway.
    Title: MAP7 Promotes Breast Cancer Cell Migration and Invasion by Regulating the NF-B Pathway.
  3. Clinical Significance of MAP-7 and FOXC1 in Egyptian Acute Myeloid Leukemia Patients.
    Title: Clinical Significance of MAP-7 and FOXC1 in Egyptian Acute Myeloid Leukemia Patients.
  4. Structural and functional insight into regulation of kinesin-1 by microtubule-associated protein MAP7.
    Title: Structural and functional insight into regulation of kinesin-1 by microtubule-associated protein MAP7.
  5. Plasma Exosomal CircNEK9 Accelerates the Progression of Gastric Cancer via miR-409-3p/MAP7 Axis.
    Title: Plasma Exosomal CircNEK9 Accelerates the Progression of Gastric Cancer via miR-409-3p/MAP7 Axis.
  6. MAP7 interacts with RC3H1 and cooperatively regulate cell-cycle progression of cervical cancer cells via activating the NF-kappaB signaling.
    Title: MAP7 interacts with RC3H1 and cooperatively regulate cell-cycle progression of cervical cancer cells via activating the NF-κB signaling.
  7. MAP7 proteins are microtubule-tethered kinesin-1 activators, with which the motor transiently interacts as it moves along microtubules.
    Title: MAP7 family proteins regulate kinesin-1 recruitment and activation.
  8. Here we show that in HeLa cells, the paralogous MT-associated proteins Map7 and Map7D1 (Map7/7D1) form an interdependent regulatory loop with Disheveled, the critical signal transducer in Wnt signaling
    Title: Map7/7D1 and Dvl form a feedback loop that facilitates microtubule remodeling and Wnt5a signaling.
  9. findings demonstrate the efficacy of quantitative proteomics for identifying effector-host protein interactions and suggest that vesicular trafficking is a crucial cellular process that may be targeted by NleB1 and EspL through their interaction with ensconsin.
    Title: Quantitative Mass Spectrometry Identifies Novel Host Binding Partners for Pathogenic Escherichia coli Type III Secretion System Effectors.
  10. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
    Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Submit: New GeneRIF Correction See all GeneRIFs (13)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables signaling receptor binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables structural molecule activity TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in establishment or maintenance of cell polarity TAS
Traceable Author Statement
more info
 PubMed 
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein localization to plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in response to osmotic stress ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in axon ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in basolateral plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  
part_of microtubule associated complex TAS
Traceable Author Statement
more info
 PubMed 
is_active_in microtubule cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in microtubule cytoskeleton IDA
Inferred from Direct Assay
more info
  
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ensconsin
Names
dJ325F22.2 (microtubule-associated protein 7 (EMAP115, E-MAP-115))
epithelial microtubule-associated protein of 115 kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001198608.3 → NP_001185537.1  ensconsin isoform 1

    See identical proteins and their annotated locations for NP_001185537.1

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    Consensus CDS
    CCDS56455.1
    UniProtKB/TrEMBL
    B7ZB64
    Conserved Domains (1) summary
    pfam05672
    Location:483 → 641
    MAP7; MAP7 (E-MAP-115) family

  2. NM_001198609.2 → NP_001185538.1  ensconsin isoform 2

    See identical proteins and their annotated locations for NP_001185538.1

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    Consensus CDS
    CCDS75527.1
    UniProtKB/TrEMBL
    A0A087WZ40, B7ZB64
    Related
    ENSP00000482335.1, ENST00000617204.4
    Conserved Domains (2) summary
    PTZ00108
    Location:101 → 317
    PTZ00108; DNA topoisomerase 2-like protein; Provisional
    pfam05672
    Location:491 → 649
    MAP7; MAP7 (E-MAP-115) family

  3. NM_001198611.3 → NP_001185540.1  ensconsin isoform 4

    See identical proteins and their annotated locations for NP_001185540.1

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    Consensus CDS
    CCDS56454.1
    UniProtKB/TrEMBL
    B7ZB64
    Related
    ENSP00000400790.2, ENST00000438100.6
    Conserved Domains (3) summary
    PTZ00108
    Location:127 → 406
    PTZ00108; DNA topoisomerase 2-like protein; Provisional
    pfam17380
    Location:87 → 173
    DUF5401; Family of unknown function (DUF5401)
    pfam05672
    Location:446 → 604
    MAP7; MAP7 (E-MAP-115) family

  4. NM_001198614.2 → NP_001185543.1  ensconsin isoform 1

    See identical proteins and their annotated locations for NP_001185543.1

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    Consensus CDS
    CCDS56455.1
    UniProtKB/TrEMBL
    B7ZB64
    Related
    ENSP00000414712.1, ENST00000454590.5
    Conserved Domains (1) summary
    pfam05672
    Location:483 → 641
    MAP7; MAP7 (E-MAP-115) family

  5. NM_001198615.3 → NP_001185544.1  ensconsin isoform 5

    Status: REVIEWED

    Source sequence(s)
    AL023284
    Consensus CDS
    CCDS56453.1
    UniProtKB/TrEMBL
    B2R704
    Related
    ENSP00000445737.1, ENST00000544465.5
    Conserved Domains (2) summary
    pfam05672
    Location:448 → 604
    MAP7; MAP7 (E-MAP-115) family
    pfam11262
    Location:69 → 141
    Tho2; Transcription factor/nuclear export subunit protein 2

  6. NM_001198616.3 → NP_001185545.1  ensconsin isoform 6

    See identical proteins and their annotated locations for NP_001185545.1

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL024508
    Consensus CDS
    CCDS75529.1
    UniProtKB/TrEMBL
    B2R704
    Related
    ENSP00000482356.1, ENST00000618822.4
    Conserved Domains (2) summary
    pfam05672
    Location:426 → 582
    MAP7; MAP7 (E-MAP-115) family
    pfam11262
    Location:84 → 156
    Tho2; Transcription factor/nuclear export subunit protein 2

  7. NM_001198617.3 → NP_001185546.1  ensconsin isoform 7

    See identical proteins and their annotated locations for NP_001185546.1

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL024508
    Consensus CDS
    CCDS75528.1
    UniProtKB/TrEMBL
    B2R704
    Related
    ENSP00000483511.1, ENST00000616617.4
    Conserved Domains (1) summary
    pfam05672
    Location:369 → 525
    MAP7; MAP7 (E-MAP-115) family

  8. NM_001198618.2 → NP_001185547.1  ensconsin isoform 8

    See identical proteins and their annotated locations for NP_001185547.1

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    Consensus CDS
    CCDS56452.1
    UniProtKB/TrEMBL
    B7Z3Y3
    Related
    ENSP00000414879.2, ENST00000432797.6
    Conserved Domains (1) summary
    pfam05672
    Location:315 → 473
    MAP7; MAP7 (E-MAP-115) family

  9. NM_001198619.2 → NP_001185548.1  ensconsin isoform 8

    See identical proteins and their annotated locations for NP_001185548.1

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    Consensus CDS
    CCDS56452.1
    UniProtKB/TrEMBL
    B7Z3Y3
    Related
    ENSP00000482998.1, ENST00000611373.1
    Conserved Domains (1) summary
    pfam05672
    Location:315 → 473
    MAP7; MAP7 (E-MAP-115) family

  10. NM_001388328.1 → NP_001375257.1  ensconsin isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    Consensus CDS
    CCDS75527.1
    UniProtKB/TrEMBL
    A0A087WZ40, B7ZB64
    Conserved Domains (2) summary
    PTZ00108
    Location:101 → 317
    PTZ00108; DNA topoisomerase 2-like protein; Provisional
    pfam05672
    Location:491 → 649
    MAP7; MAP7 (E-MAP-115) family

  11. NM_001388329.1 → NP_001375258.1  ensconsin isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    Consensus CDS
    CCDS75527.1
    UniProtKB/TrEMBL
    A0A087WZ40, B7ZB64
    Conserved Domains (2) summary
    PTZ00108
    Location:101 → 317
    PTZ00108; DNA topoisomerase 2-like protein; Provisional
    pfam05672
    Location:491 → 649
    MAP7; MAP7 (E-MAP-115) family

  12. NM_001388330.1 → NP_001375259.1  ensconsin isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    Consensus CDS
    CCDS75527.1
    UniProtKB/TrEMBL
    A0A087WZ40, B7ZB64
    Conserved Domains (2) summary
    PTZ00108
    Location:101 → 317
    PTZ00108; DNA topoisomerase 2-like protein; Provisional
    pfam05672
    Location:491 → 649
    MAP7; MAP7 (E-MAP-115) family

  13. NM_001388331.1 → NP_001375260.1  ensconsin isoform 9

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    UniProtKB/TrEMBL
    B7ZB64
    Conserved Domains (1) summary
    pfam05672
    Location:490 → 648
    MAP7; MAP7 (E-MAP-115) family

  14. NM_001388332.1 → NP_001375261.1  ensconsin isoform 1

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    Consensus CDS
    CCDS56455.1
    UniProtKB/TrEMBL
    B7ZB64
    Conserved Domains (1) summary
    pfam05672
    Location:483 → 641
    MAP7; MAP7 (E-MAP-115) family

  15. NM_001388333.1 → NP_001375262.1  ensconsin isoform 1

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    Consensus CDS
    CCDS56455.1
    UniProtKB/TrEMBL
    B7ZB64
    Conserved Domains (1) summary
    pfam05672
    Location:483 → 641
    MAP7; MAP7 (E-MAP-115) family

  16. NM_001388334.1 → NP_001375263.1  ensconsin isoform 10

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL024508
    UniProtKB/TrEMBL
    B2R704
    Conserved Domains (2) summary
    PTZ00108
    Location:79 → 295
    PTZ00108; DNA topoisomerase 2-like protein; Provisional
    pfam05672
    Location:469 → 627
    MAP7; MAP7 (E-MAP-115) family

  17. NM_001388335.1 → NP_001375264.1  ensconsin isoform 11

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL024508
    UniProtKB/TrEMBL
    B2R704
    Conserved Domains (1) summary
    pfam05672
    Location:468 → 626
    MAP7; MAP7 (E-MAP-115) family

  18. NM_001388336.1 → NP_001375265.1  ensconsin isoform 12

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    UniProtKB/TrEMBL
    B7ZB64
    Conserved Domains (2) summary
    PTZ00108
    Location:127 → 414
    PTZ00108; DNA topoisomerase 2-like protein; Provisional
    pfam05672
    Location:454 → 612
    MAP7; MAP7 (E-MAP-115) family

  19. NM_001388337.1 → NP_001375266.1  ensconsin isoform 12

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    UniProtKB/TrEMBL
    B7ZB64
    Conserved Domains (2) summary
    PTZ00108
    Location:127 → 414
    PTZ00108; DNA topoisomerase 2-like protein; Provisional
    pfam05672
    Location:454 → 612
    MAP7; MAP7 (E-MAP-115) family

  20. NM_001388338.1 → NP_001375267.1  ensconsin isoform 12

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    UniProtKB/TrEMBL
    B7ZB64
    Conserved Domains (2) summary
    PTZ00108
    Location:127 → 414
    PTZ00108; DNA topoisomerase 2-like protein; Provisional
    pfam05672
    Location:454 → 612
    MAP7; MAP7 (E-MAP-115) family

  21. NM_001388339.1 → NP_001375268.1  ensconsin isoform 13

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL024508
    UniProtKB/TrEMBL
    B2R704
    Conserved Domains (2) summary
    PTZ00108
    Location:105 → 384
    PTZ00108; DNA topoisomerase 2-like protein; Provisional
    pfam05672
    Location:424 → 605
    MAP7; MAP7 (E-MAP-115) family

  22. NM_001388340.1 → NP_001375269.1  ensconsin isoform 4

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    Consensus CDS
    CCDS56454.1
    UniProtKB/TrEMBL
    B7ZB64
    Conserved Domains (3) summary
    PTZ00108
    Location:127 → 406
    PTZ00108; DNA topoisomerase 2-like protein; Provisional
    pfam17380
    Location:87 → 173
    DUF5401; Family of unknown function (DUF5401)
    pfam05672
    Location:446 → 604
    MAP7; MAP7 (E-MAP-115) family

  23. NM_001388341.1 → NP_001375270.1  ensconsin isoform 4

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    Consensus CDS
    CCDS56454.1
    UniProtKB/TrEMBL
    B7ZB64
    Conserved Domains (3) summary
    PTZ00108
    Location:127 → 406
    PTZ00108; DNA topoisomerase 2-like protein; Provisional
    pfam17380
    Location:87 → 173
    DUF5401; Family of unknown function (DUF5401)
    pfam05672
    Location:446 → 604
    MAP7; MAP7 (E-MAP-115) family

  24. NM_001388342.1 → NP_001375271.1  ensconsin isoform 14

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL024508
    UniProtKB/TrEMBL
    B2R704
    Conserved Domains (2) summary
    PTZ00108
    Location:105 → 392
    PTZ00108; DNA topoisomerase 2-like protein; Provisional
    pfam05672
    Location:432 → 590
    MAP7; MAP7 (E-MAP-115) family

  25. NM_001388343.1 → NP_001375272.1  ensconsin isoform 15

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    UniProtKB/TrEMBL
    B7ZB64
    Conserved Domains (2) summary
    pfam17380
    Location:8 → 122
    DUF5401; Family of unknown function (DUF5401)
    pfam05672
    Location:424 → 582
    MAP7; MAP7 (E-MAP-115) family

  26. NM_001388344.1 → NP_001375273.1  ensconsin isoform 16

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    UniProtKB/TrEMBL
    B7ZB64
    Conserved Domains (2) summary
    PTZ00108
    Location:101 → 363
    PTZ00108; DNA topoisomerase 2-like protein; Provisional
    pfam05672
    Location:403 → 561
    MAP7; MAP7 (E-MAP-115) family

  27. NM_001388345.1 → NP_001375274.1  ensconsin isoform 17

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    UniProtKB/TrEMBL
    B7ZB64
    Conserved Domains (1) summary
    pfam05672
    Location:352 → 510
    MAP7; MAP7 (E-MAP-115) family

  28. NM_001388346.1 → NP_001375275.1  ensconsin isoform 17

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    UniProtKB/TrEMBL
    B7ZB64
    Conserved Domains (1) summary
    pfam05672
    Location:352 → 510
    MAP7; MAP7 (E-MAP-115) family

  29. NM_001388347.1 → NP_001375276.1  ensconsin isoform 18

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL024508
    UniProtKB/TrEMBL
    B2R704
    Conserved Domains (1) summary
    pfam05672
    Location:330 → 488
    MAP7; MAP7 (E-MAP-115) family

  30. NM_001388348.1 → NP_001375277.1  ensconsin isoform 8

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    Consensus CDS
    CCDS56452.1
    UniProtKB/TrEMBL
    B7Z3Y3
    Conserved Domains (1) summary
    pfam05672
    Location:315 → 473
    MAP7; MAP7 (E-MAP-115) family

  31. NM_001388349.1 → NP_001375278.1  ensconsin isoform 8

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    Consensus CDS
    CCDS56452.1
    UniProtKB/TrEMBL
    B7Z3Y3
    Conserved Domains (1) summary
    pfam05672
    Location:315 → 473
    MAP7; MAP7 (E-MAP-115) family

  32. NM_001388350.1 → NP_001375279.1  ensconsin isoform 20

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    UniProtKB/TrEMBL
    B7Z3Y3
    Conserved Domains (1) summary
    pfam05672
    Location:278 → 436
    MAP7; MAP7 (E-MAP-115) family

  33. NM_001388351.1 → NP_001375280.1  ensconsin isoform 20

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    UniProtKB/TrEMBL
    B7Z3Y3
    Conserved Domains (1) summary
    pfam05672
    Location:278 → 436
    MAP7; MAP7 (E-MAP-115) family

  34. NM_001388352.1 → NP_001375281.1  ensconsin isoform 21

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL024508
    UniProtKB/TrEMBL
    B7Z3Y3
    Conserved Domains (1) summary
    pfam05672
    Location:233 → 391
    MAP7; MAP7 (E-MAP-115) family

  35. NM_001388353.1 → NP_001375282.1  ensconsin isoform 22

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL133511
    Conserved Domains (1) summary
    pfam05672
    Location:330 → 366
    MAP7; MAP7 (E-MAP-115) family

  36. NM_003980.6 → NP_003971.1  ensconsin isoform 3

    See identical proteins and their annotated locations for NP_003971.1

    Status: REVIEWED

    Source sequence(s)
    AL023284, AL024508
    Consensus CDS
    CCDS5178.1
    UniProtKB/Swiss-Prot
    B7Z290, B7Z400, B7Z5S7, B7Z9U7, C9JPS0, E9PCP3, F5H1E2, Q14244, Q7Z6S0, Q8TAU5, Q9NY82, Q9NY83
    UniProtKB/TrEMBL
    B2R704
    Related
    ENSP00000346581.2, ENST00000354570.8
    Conserved Domains (2) summary
    pfam05672
    Location:463 → 619
    MAP7; MAP7 (E-MAP-115) family
    pfam11262
    Location:84 → 156
    Tho2; Transcription factor/nuclear export subunit protein 2

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    136342734..136550422 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047419515.1 → XP_047275471.1  ensconsin isoform X3

  2. XM_011536246.3 → XP_011534548.1  ensconsin isoform X2

    UniProtKB/TrEMBL
    B2R704
    Conserved Domains (2) summary
    pfam05672
    Location:419 → 575
    MAP7; MAP7 (E-MAP-115) family
    pfam11262
    Location:69 → 141
    Tho2; Transcription factor/nuclear export subunit protein 2

  3. XM_011536243.3 → XP_011534545.1  ensconsin isoform X1

    UniProtKB/TrEMBL
    B2R704
    Conserved Domains (2) summary
    pfam05672
    Location:456 → 612
    MAP7; MAP7 (E-MAP-115) family
    pfam11262
    Location:69 → 141
    Tho2; Transcription factor/nuclear export subunit protein 2

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    137530867..137738614 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054356743.1 → XP_054212718.1  ensconsin isoform X3

  2. XM_054356742.1 → XP_054212717.1  ensconsin isoform X2

  3. XM_054356741.1 → XP_054212716.1  ensconsin isoform X1

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q14244.1 GenPept UniProtKB/Swiss-Prot:Q14244

Gene LinkOut

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