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SOCS2 suppressor of cytokine signaling 2 [ Homo sapiens (human) ]

Gene ID: 8835, updated on 11-Apr-2024

Summary

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Official Symbol
SOCS2provided by HGNC
Official Full Name
suppressor of cytokine signaling 2provided by HGNC
Primary source
HGNC:HGNC:19382
See related
Ensembl:ENSG00000120833 MIM:605117; AllianceGenome:HGNC:19382
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CIS2; SSI2; Cish2; SSI-2; SOCS-2; STATI2
Summary
This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
Expression
Broad expression in endometrium (RPKM 13.5), prostate (RPKM 10.5) and 22 other tissues See more
Orthologs
mouse all
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Genomic context

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Location:
12q22
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (93569969..93626236)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (93551422..93607676)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (93963745..93970521)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L42 Neighboring gene RNA, 7SL, cytoplasmic 737, pseudogene Neighboring gene uncharacterized LOC124902985 Neighboring gene MPRA-validated peak1894 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4711 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4712 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4713 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4714 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4715 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6771 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:93975910-93976410 Neighboring gene SOCS2 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:93976411-93976911 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:93977698-93978644 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:93978645-93979590 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:93984897-93985456 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr12:94018330-94019529 Neighboring gene phosphoglycerate mutase 1 (brain) pseudogene Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:94070392-94071207 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:94071208-94072022 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:94072839-94073653 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr12:94092983-94093855 Neighboring gene CASP2 and RIPK1 domain containing adaptor with death domain Neighboring gene CRADD antisense RNA 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Upregulation of SOCS2 causes mitochondrial dysfunction and promotes ferroptosis in pancreatic cancer cells. He M, et al. Acta Biochim Pol, 2023 Feb 3. PMID 36735705
  2. Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands. Linossi EM, et al. Nat Commun, 2021 Dec 2. PMID 34857742, Free PMC Article
  3. SOCS2 is part of a highly prognostic 4-gene signature in AML and promotes disease aggressiveness. Nguyen CH, et al. Sci Rep, 2019 Jun 24. PMID 31235852, Free PMC Article
  4. RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2. Chen M, et al. Hepatology, 2018 Jun. PMID 29171881
  5. A herpes simplex virus type 2-encoded microRNA promotes tumor cell metastasis by targeting suppressor of cytokine signaling 2 in lung cancer. Wang X, et al. Tumour Biol, 2017 May. PMID 28468588

See all (153) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Analysis of epigenetic clocks links yoga, sleep, education, reduced meat intake, coffee, and a SOCS2 gene variant to slower epigenetic aging.
    Title: Analysis of epigenetic clocks links yoga, sleep, education, reduced meat intake, coffee, and a SOCS2 gene variant to slower epigenetic aging.
  2. Inhibition of miR-578 through SOCS2-dependent manner reverses gefitinib resistance in NSCLC cells.
    Title: Inhibition of miR-578 through SOCS2-dependent manner reverses gefitinib resistance in NSCLC cells.
  3. SOCS2 inhibits hepatoblastoma metastasis via downregulation of the JAK2/STAT5 signal pathway.
    Title: SOCS2 inhibits hepatoblastoma metastasis via downregulation of the JAK2/STAT5 signal pathway.
  4. CTRP6 protects against ferroptosis to drive lung cancer progression and metastasis by destabilizing SOCS2 and augmenting the xCT/GPX4 pathway.
    Title: CTRP6 protects against ferroptosis to drive lung cancer progression and metastasis by destabilizing SOCS2 and augmenting the xCT/GPX4 pathway.
  5. MiR-532-3p inhibited the methylation of SOCS2 to suppress the progression of PC by targeting DNMT3A.
    Title: MiR-532-3p inhibited the methylation of SOCS2 to suppress the progression of PC by targeting DNMT3A.
  6. Upregulation of SOCS2 causes mitochondrial dysfunction and promotes ferroptosis in pancreatic cancer cells.
    Title: Upregulation of SOCS2 causes mitochondrial dysfunction and promotes ferroptosis in pancreatic cancer cells.
  7. circ_0008797 attenuates non-small cell lung cancer proliferation, metastasis, and aerobic glycolysis by sponging miR-301a-3p/SOCS2.
    Title: circ_0008797 attenuates non-small cell lung cancer proliferation, metastasis, and aerobic glycolysis by sponging miR-301a-3p/SOCS2.
  8. miR-3648 promotes lung adenocarcinoma-genesis by inhibiting SOCS2 (suppressor of cytokine signaling 2).
    Title: miR-3648 promotes lung adenocarcinoma-genesis by inhibiting SOCS2 (suppressor of cytokine signaling 2).
  9. MicroRNA -196b is related to the overall survival of patients with esophageal squamous cell carcinoma and facilitates tumor progression by regulating SOCS2 (Suppressor Of Cytokine Signaling 2).
    Title: MicroRNA -196b is related to the overall survival of patients with esophageal squamous cell carcinoma and facilitates tumor progression by regulating SOCS2 (Suppressor Of Cytokine Signaling 2).
  10. Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands.
    Title: Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands.
Submit: New GeneRIF Correction See all GeneRIFs (83)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide analysis of hepatic lipid content in extreme obesity.
EBI GWAS Catalog
Genome-wide association analysis identifies 20 loci that influence adult height.
EBI GWAS Catalog
Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.
EBI GWAS Catalog
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
EBI GWAS Catalog
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
EBI GWAS Catalog
Many sequence variants affecting diversity of adult human height.
EBI GWAS Catalog
Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

HIV-1 interactions

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Protein interactions

Protein Gene Interaction Pubs
Tat tat HIV-1 Tat upregulates the expression of suppressor of cytokine signaling 2 (SOCS2) in human primary T cells PubMed
tat HIV-1 Tat impairs the IFNgamma-receptor signaling pathway in primary human monocytes at the level of STAT1 activation via Tat-dependent induction of suppressor of cytokine signaling-2 (SOCS-2) activity PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables JAK pathway signal transduction adaptor activity TAS
Traceable Author Statement
more info
 PubMed 
enables growth hormone receptor binding NAS
Non-traceable Author Statement
more info
 PubMed 
enables insulin-like growth factor receptor binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
  
involved_in cellular response to hormone stimulus IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in growth hormone receptor signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
  
involved_in lactation IEA
Inferred from Electronic Annotation
more info
  
involved_in mammary gland alveolus development IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of apoptotic process TAS
Traceable Author Statement
more info
 PubMed 
involved_in negative regulation of multicellular organism growth IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
  
involved_in phosphatidylinositol phosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of neuron differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of cell growth NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in regulation of signal transduction NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in response to estradiol IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm NAS
Non-traceable Author Statement
more info
 PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
  
part_of phosphatidylinositol 3-kinase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
suppressor of cytokine signaling 2
Names
CIS-2
STAT-induced STAT inhibitor 2
cytokine-inducible SH2 protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001270467.2 → NP_001257396.1  suppressor of cytokine signaling 2

    See identical proteins and their annotated locations for NP_001257396.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 5. Variants 1-6 encode the same protein.
    Source sequence(s)
    AC012085, AI129818, AK313165, BC010399, BJ996504, CD699665, DA709082
    Consensus CDS
    CCDS9047.1
    UniProtKB/Swiss-Prot
    A8K3D1, O14508, O14542, O95102, Q9UKS5
    UniProtKB/TrEMBL
    B5BU82
    Related
    ENSP00000448815.1, ENST00000549206.5
    Conserved Domains (2) summary
    cd10383
    Location:40 → 142
    SH2_SOCS2; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03736
    Location:158 → 198
    SOCS_SOCS2; SOCS (suppressors of cytokine signaling) box of SOCS2-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS2 has recently been shown to regulate ...

  2. NM_001270468.2 → NP_001257397.1  suppressor of cytokine signaling 2

    See identical proteins and their annotated locations for NP_001257397.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 5. Variants 1-6 encode the same protein.
    Source sequence(s)
    AI129818, AK313165, BC010399, BJ996504, CD699665, DA490057
    Consensus CDS
    CCDS9047.1
    UniProtKB/Swiss-Prot
    A8K3D1, O14508, O14542, O95102, Q9UKS5
    UniProtKB/TrEMBL
    B5BU82
    Related
    ENSP00000442898.2, ENST00000536696.6
    Conserved Domains (2) summary
    cd10383
    Location:40 → 142
    SH2_SOCS2; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03736
    Location:158 → 198
    SOCS_SOCS2; SOCS (suppressors of cytokine signaling) box of SOCS2-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS2 has recently been shown to regulate ...

  3. NM_001270469.2 → NP_001257398.1  suppressor of cytokine signaling 2

    See identical proteins and their annotated locations for NP_001257398.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 5. Variants 1-6 encode the same protein.
    Source sequence(s)
    AI129818, AK313165, BC010399, BJ996504, CD699665, DB054162
    Consensus CDS
    CCDS9047.1
    UniProtKB/Swiss-Prot
    A8K3D1, O14508, O14542, O95102, Q9UKS5
    UniProtKB/TrEMBL
    B5BU82
    Related
    ENSP00000447161.1, ENST00000549122.5
    Conserved Domains (2) summary
    cd10383
    Location:40 → 142
    SH2_SOCS2; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03736
    Location:158 → 198
    SOCS_SOCS2; SOCS (suppressors of cytokine signaling) box of SOCS2-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS2 has recently been shown to regulate ...

  4. NM_001270470.1 → NP_001257399.1  suppressor of cytokine signaling 2

    See identical proteins and their annotated locations for NP_001257399.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) represents the longest transcript. Variants 1-6 encode the same protein.
    Source sequence(s)
    AI129818, AK313165, BC010399, BJ996504, CD699665, DB054162, DB481261
    Consensus CDS
    CCDS9047.1
    UniProtKB/Swiss-Prot
    A8K3D1, O14508, O14542, O95102, Q9UKS5
    UniProtKB/TrEMBL
    B5BU82
    Related
    ENSP00000481249.1, ENST00000622746.4
    Conserved Domains (2) summary
    cd10383
    Location:40 → 142
    SH2_SOCS2; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03736
    Location:158 → 198
    SOCS_SOCS2; SOCS (suppressors of cytokine signaling) box of SOCS2-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS2 has recently been shown to regulate ...

  5. NM_001270471.2 → NP_001257400.1  suppressor of cytokine signaling 2

    See identical proteins and their annotated locations for NP_001257400.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR, compared to variant 5. Variants 1-6 encode the same protein.
    Source sequence(s)
    AI129818, AK313165, BC010399, BJ996504, CD699665, DC300183
    Consensus CDS
    CCDS9047.1
    UniProtKB/Swiss-Prot
    A8K3D1, O14508, O14542, O95102, Q9UKS5
    UniProtKB/TrEMBL
    B5BU82
    Related
    ENSP00000449227.1, ENST00000551556.2
    Conserved Domains (2) summary
    cd10383
    Location:40 → 142
    SH2_SOCS2; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03736
    Location:158 → 198
    SOCS_SOCS2; SOCS (suppressors of cytokine signaling) box of SOCS2-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS2 has recently been shown to regulate ...

  6. NM_003877.5 → NP_003868.1  suppressor of cytokine signaling 2

    See identical proteins and their annotated locations for NP_003868.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) differs in the 5' UTR, compared to variant 5. Variants 1-6 encode the same protein.
    Source sequence(s)
    AI129818, AK313165, AL522912, BC010399, BJ996504, CD699665
    Consensus CDS
    CCDS9047.1
    UniProtKB/Swiss-Prot
    A8K3D1, O14508, O14542, O95102, Q9UKS5
    UniProtKB/TrEMBL
    B5BU82
    Related
    ENSP00000339428.2, ENST00000340600.6
    Conserved Domains (2) summary
    cd10383
    Location:40 → 142
    SH2_SOCS2; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03736
    Location:158 → 198
    SOCS_SOCS2; SOCS (suppressors of cytokine signaling) box of SOCS2-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS2 has recently been shown to regulate ...

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    93569969..93626236
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017020147.2 → XP_016875636.1  suppressor of cytokine signaling 2 isoform X1

    UniProtKB/TrEMBL
    B5BU82

  2. XM_017020152.2 → XP_016875641.1  suppressor of cytokine signaling 2 isoform X1

    UniProtKB/TrEMBL
    B5BU82

  3. XM_047429808.1 → XP_047285764.1  suppressor of cytokine signaling 2 isoform X6

    UniProtKB/Swiss-Prot
    A8K3D1, O14508, O14542, O95102, Q9UKS5

  4. XM_017020148.3 → XP_016875637.1  suppressor of cytokine signaling 2 isoform X1

    UniProtKB/TrEMBL
    B5BU82

  5. XM_017020151.2 → XP_016875640.1  suppressor of cytokine signaling 2 isoform X1

    UniProtKB/TrEMBL
    B5BU82

  6. XM_047429807.1 → XP_047285763.1  suppressor of cytokine signaling 2 isoform X1

  7. XM_017020149.2 → XP_016875638.1  suppressor of cytokine signaling 2 isoform X1

    UniProtKB/TrEMBL
    B5BU82

  8. XM_011538935.2 → XP_011537237.1  suppressor of cytokine signaling 2 isoform X4

    UniProtKB/TrEMBL
    B5BU82
    Conserved Domains (2) summary
    cd10383
    Location:40 → 142
    SH2_SOCS2; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03736
    Location:158 → 198
    SOCS_SOCS2; SOCS (suppressors of cytokine signaling) box of SOCS2-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS2 has recently been shown to regulate ...

  9. XM_011538936.2 → XP_011537238.1  suppressor of cytokine signaling 2 isoform X5

    UniProtKB/TrEMBL
    B5BU82
    Conserved Domains (2) summary
    cd10383
    Location:40 → 142
    SH2_SOCS2; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03736
    Location:158 → 197
    SOCS_SOCS2; SOCS (suppressors of cytokine signaling) box of SOCS2-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS2 has recently been shown to regulate ...

  10. XM_011538929.2 → XP_011537231.1  suppressor of cytokine signaling 2 isoform X3

    See identical proteins and their annotated locations for XP_011537231.1

    UniProtKB/TrEMBL
    B5BU82
    Conserved Domains (2) summary
    cd10383
    Location:40 → 142
    SH2_SOCS2; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03736
    Location:158 → 197
    SOCS_SOCS2; SOCS (suppressors of cytokine signaling) box of SOCS2-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS2 has recently been shown to regulate ...

  11. XM_017020155.3 → XP_016875644.1  suppressor of cytokine signaling 2 isoform X2

    UniProtKB/TrEMBL
    B5BU82

RNA

  1. XR_944810.2 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    93551422..93607676
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054373709.1 → XP_054229684.1  suppressor of cytokine signaling 2 isoform X1

  2. XM_054373713.1 → XP_054229688.1  suppressor of cytokine signaling 2 isoform X1

  3. XM_054373710.1 → XP_054229685.1  suppressor of cytokine signaling 2 isoform X1

  4. XM_054373712.1 → XP_054229687.1  suppressor of cytokine signaling 2 isoform X1

  5. XM_054373711.1 → XP_054229686.1  suppressor of cytokine signaling 2 isoform X1

  6. XM_054373716.1 → XP_054229691.1  suppressor of cytokine signaling 2 isoform X4

  7. XM_054373717.1 → XP_054229692.1  suppressor of cytokine signaling 2 isoform X5

  8. XM_054373715.1 → XP_054229690.1  suppressor of cytokine signaling 2 isoform X3

  9. XM_054373714.1 → XP_054229689.1  suppressor of cytokine signaling 2 isoform X2

  10. XM_054373708.1 → XP_054229683.1  suppressor of cytokine signaling 2 isoform X1

RNA

  1. XR_008488706.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O14508.1 GenPept UniProtKB/Swiss-Prot:O14508

Gene LinkOut

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