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CEACAM18 CEA cell adhesion molecule 18 [ Homo sapiens (human) ]

Gene ID: 729767, updated on 5-Mar-2024

Summary

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Official Symbol
CEACAM18provided by HGNC
Official Full Name
CEA cell adhesion molecule 18provided by HGNC
Primary source
HGNC:HGNC:31949
See related
Ensembl:ENSG00000213822 AllianceGenome:HGNC:31949
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in duodenum (RPKM 5.4) and small intestine (RPKM 3.6) See more
Orthologs
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Genomic context

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See CEACAM18 in Genome Data Viewer
Location:
19q13.41
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (51478539..51491301)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (54567160..54579923)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (51981793..51994555)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:51966471-51967219 Neighboring gene sialic acid binding Ig like lectin 25, pseudogene Neighboring gene sialic acid binding Ig like lectin 26, pseudogene Neighboring gene ReSE screen-validated silencer GRCh37_chr19:51990573-51990732 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:51991976-51992156 Neighboring gene sialic acid binding Ig like lectin 12 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:52002817-52003316 Neighboring gene sialic acid binding Ig like lectin 27, pseudogene Neighboring gene sialic acid binding Ig like lectin 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. The old CEACAMs find their new role in tumor immunotherapy. Han ZW, et al. Invest New Drugs, 2020 Dec. PMID 32488569
  2. Identification of a novel group of evolutionarily conserved members within the rapidly diverging murine Cea family. Zebhauser R, et al. Genomics, 2005 Nov. PMID 16139472

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Homology

General protein information

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Preferred Names
carcinoembryonic antigen-related cell adhesion molecule 18
Names
carcinoembryonic antigen related cell adhesion molecule 18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001405061.1 → NP_001391990.1  carcinoembryonic antigen-related cell adhesion molecule 18 precursor

    Status: VALIDATED

    Source sequence(s)
    AC020914
    UniProtKB/Swiss-Prot
    A8MTB9, C9JN24
    Related
    ENSP00000379738.4, ENST00000396477.5

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    51478539..51491301
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054328435.1 → XP_054184410.1  carcinoembryonic antigen-related cell adhesion molecule 18 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    54567160..54579923
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054321928.1 → XP_054177903.1  carcinoembryonic antigen-related cell adhesion molecule 18 isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001080405.1: Suppressed sequence

    Description
    NM_001080405.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.

  2. NM_001278392.2: Suppressed sequence

    Description
    NM_001278392.2: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A8MTB9.4 GenPept UniProtKB/Swiss-Prot:A8MTB9

Gene LinkOut

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