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XAGE1C X antigen family, member 1C [ Homo sapiens (human) ]

Gene ID: 653048, discontinued on 12-Apr-2014

Summary

Official Symbol
XAGE1Cprovided by HGNC
Official Full Name
X antigen family, member 1Cprovided by HGNC
Primary source
HGNC:HGNC:30679
See related
MIM:300744
Gene type
protein coding
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CTP9; CT12.1; GAGED2; XAGE-1; CT12.1C
Summary
This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene, in addition to alternative transcription start sites, results in multiple transcript variants. [provided by RefSeq, Jan 2010]
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Genomic context

Location:
Xp11.22
Annotation release Status Assembly Chr Location
105 latest, but not current GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (52511761..52516905)

General protein information

Names
X antigen family, member 1C
G antigen family D member 2
X antigen family member 1
cancer/testis antigen 12.1
cancer/testis antigen family 12, member 1c
cancer/testis associated protein
protein XAGE-1