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OR56A3 olfactory receptor family 56 subfamily A member 3 [ Homo sapiens (human) ]

Gene ID: 390083, updated on 5-Mar-2024

Summary

Official Symbol
OR56A3provided by HGNC
Official Full Name
olfactory receptor family 56 subfamily A member 3provided by HGNC
Primary source
HGNC:HGNC:14786
See related
Ensembl:ENSG00000184478 AllianceGenome:HGNC:14786
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR56A6; OR56A2P; OR56A3P
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

Location:
11p15.4
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (5942251..6022010)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (6000747..6080512)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (5963481..5972577)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112268071 Neighboring gene olfactory receptor family 52 subfamily E member 5 Neighboring gene olfactory receptor family 52 subfamily Q member 1 pseudogene Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:5943920-5945119 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr11:5949120-5950319 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr11:5958637-5959836 Neighboring gene olfactory receptor family 56 subfamily A member 5 Neighboring gene uncharacterized LOC124902621 Neighboring gene olfactory receptor family 52 subfamily L member 1 Neighboring gene keratin 18 pseudogene 58 Neighboring gene olfactory receptor family 56 subfamily A member 4 Neighboring gene uncharacterized LOC107984303 Neighboring gene RNA, 5S ribosomal pseudogene 329 Neighboring gene olfactory receptor family 56 subfamily A member 1 Neighboring gene olfactory receptor family 56 subfamily A member 7 pseudogene Neighboring gene olfactory receptor family 52 subfamily L member 2 pseudogene

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
olfactory receptor 56A3
Names
olfactory receptor 56A6
olfactory receptor OR11-51
olfactory receptor, family 56, subfamily A, member 2 pseudogene
olfactory receptor, family 56, subfamily A, member 3 pseudogene
olfactory receptor, family 56, subfamily A, member 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003443.3NP_001003443.2  olfactory receptor 56A3

    See identical proteins and their annotated locations for NP_001003443.2

    Status: VALIDATED

    Source sequence(s)
    AC025016
    Consensus CDS
    CCDS41614.1
    UniProtKB/Swiss-Prot
    A6NN77, Q6IFF7, Q8NH54
    UniProtKB/TrEMBL
    A0A126GWL6
    Related
    ENSP00000493059.1, ENST00000641160.1
    Conserved Domains (2) summary
    pfam00001
    Location:46296
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:46311
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    5942251..6022010
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047426926.1XP_047282882.1  olfactory receptor 56A3 isoform X1

    UniProtKB/Swiss-Prot
    A6NN77, Q6IFF7, Q8NH54
    UniProtKB/TrEMBL
    A0A126GWL6

RNA

  1. XR_007062481.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    6000747..6080512
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054368741.1XP_054224716.1  olfactory receptor 56A3 isoform X1

    UniProtKB/TrEMBL
    A0A126GVG2

RNA

  1. XR_007082413.1 RNA Sequence