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YIPF7 Yip1 domain family member 7 [ Homo sapiens (human) ]

Gene ID: 285525, updated on 5-Mar-2024

Summary

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Official Symbol
YIPF7provided by HGNC
Official Full Name
Yip1 domain family member 7provided by HGNC
Primary source
HGNC:HGNC:26825
See related
Ensembl:ENSG00000177752 MIM:619754; AllianceGenome:HGNC:26825
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Yip1b; FinGER9; YIPFalpha1b
Summary
Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and vesicle fusion with Golgi apparatus. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
mouse all
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Genomic context

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Location:
4p12
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (44622088..44662199, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (44589027..44629123, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (44624105..44653642, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374438 Neighboring gene long intergenic non-protein coding RNA 2475 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:44058850-44059376 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:44183470-44184174 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr4:44184175-44184879 Neighboring gene potassium channel tetramerization domain containing 8 Neighboring gene uncharacterized LOC107986275 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:44665473-44665974 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:44665975-44666474 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:44679656-44680544 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15397 Neighboring gene Sharpr-MPRA regulatory region 4028 Neighboring gene GTP binding elongation factor GUF1 Neighboring gene glucosamine-6-phosphate deaminase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Identification of genetic susceptibility loci for intestinal Behçet's disease. Kim SW, et al. Sci Rep, 2017 Jan 3. PMID 28045058, Free PMC Article
  2. Toward a complete human genome sequence. Sanger Center, et al. Genome Res, 1998 Nov. PMID 9847074
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Homology

Clone Names

  • FLJ39576, MGC120164

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle fusion with Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
protein YIPF7
Names
YIP1 family member 7
five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001387382.1 → NP_001374311.1  protein YIPF7 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC093852, AC096586

  2. NM_182592.3 → NP_872398.3  protein YIPF7 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC093852, AK096895, BC103996, DB299886
    Consensus CDS
    CCDS54766.2
    UniProtKB/Swiss-Prot
    J3KR00, Q3SY21, Q3SY22, Q8N8F6
    Related
    ENSP00000412696.4, ENST00000415895.9
    Conserved Domains (1) summary
    cl21557
    Location:49 → 256
    Yip1; Yip1 domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    44622088..44662199 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047450094.1 → XP_047306050.1  protein YIPF7 isoform X1

  2. XM_011513679.3 → XP_011511981.1  protein YIPF7 isoform X2

    Conserved Domains (1) summary
    cl21557
    Location:111 → 318
    Yip1; Yip1 domain

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    44589027..44629123 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054349735.1 → XP_054205710.1  protein YIPF7 isoform X1

  2. XM_054349736.1 → XP_054205711.1  protein YIPF7 isoform X2

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8N8F6.3 GenPept UniProtKB/Swiss-Prot:Q8N8F6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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