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ZNF22-AS1 ZNF22 antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 220979, updated on 5-Mar-2024

Summary

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Official Symbol
ZNF22-AS1provided by HGNC
Official Full Name
ZNF22 antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:23509
See related
Ensembl:ENSG00000165511 AllianceGenome:HGNC:23509
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C10orf25
Summary
Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in appendix (RPKM 9.1), fat (RPKM 8.9) and 25 other tissues See more
Orthologs
all
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Genomic context

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Location:
10q11.21
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (44993932..45000803, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (45874896..45881759, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (45489380..45496251, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378281 Neighboring gene Ras association domain family member 4 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:45467973-45468635 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:45468636-45469297 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3319 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2342 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:45470934-45471637 Neighboring gene Sharpr-MPRA regulatory region 8316 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:45475153-45475856 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:45475857-45476558 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:45479350-45479850 Neighboring gene DEPP autophagy regulator 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:45486450-45487141 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:45487171-45487672 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:45487673-45488172 Neighboring gene uncharacterized LOC124902530 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:45496487-45496987 Neighboring gene zinc finger protein 22 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:45510141-45510640 Neighboring gene double homeobox A pseudogene 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. The DNA sequence and comparative analysis of human chromosome 10. Deloukas P, et al. Nature, 2004 May 27. PMID 15164054
  2. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. Grupe A, et al. Am J Hum Genet, 2006 Jan. PMID 16385451, Free PMC Article
  3. Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei. Fasci D, et al. Mol Cell Proteomics, 2018 Oct. PMID 30021884, Free PMC Article
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Observational study of gene-disease association. (HuGE Navigator)
    Title: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Other Names

  • uncharacterized protein C10orf25

Clone Names

  • FLJ18393, FLJ30567

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_126421.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL353801

  2. NR_164113.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL353801
    Related
    ENST00000625168.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    44993932..45000803 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    45874896..45881759 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001039380.3: Suppressed sequence

    Description
    NM_001039380.3: This RefSeq was removed because it is now thought that this gene does not encode a protein.

  2. NM_145022.1: Suppressed sequence

    Description
    NM_145022.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5T742.3 GenPept UniProtKB/Swiss-Prot:Q5T742

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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