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LOC127825625 H3K4me1 hESC enhancer GRCh37_chr12:125798555-125799056 [ Homo sapiens (human) ]

Gene ID: 127825625, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127825625
Gene description
H3K4me1 hESC enhancer GRCh37_chr12:125798555-125799056
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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Location:
chromosome: 12
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (125314009..125314510)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (125322203..125322704)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene transmembrane protein 132B Neighboring gene uncharacterized LOC105370054 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:125764586-125765449 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:125765450-125766312 Neighboring gene uncharacterized LOC107984445 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5082 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:125813668-125814394 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:125814395-125815120 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5083 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:125861407-125861906 Neighboring gene ReSE screen-validated silencer GRCh37_chr12:125893185-125893373 Neighboring gene ReSE screen-validated silencer GRCh37_chr12:125917777-125917975 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7322 Neighboring gene NANOG hESC enhancer GRCh37_chr12:125920548-125921070 Neighboring gene Sharpr-MPRA regulatory region 9406 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr12:126022594-126023793 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5084 Neighboring gene uncharacterized LOC105370055 Neighboring gene uncharacterized LOC124903047

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_127137.1 

    Range
    101..602
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    125314009..125314510
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    125322203..125322704
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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