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LOC127398367 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:118925721-118926245 [ Homo sapiens (human) ]

Gene ID: 127398367, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127398367
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:118925721-118926245
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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Location:
chromosome: 3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (119206874..119207398)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (121926590..121927114)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene testis expressed 55 Neighboring gene uroplakin 1B Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:118925194-118925720 Neighboring gene ReSE screen-validated silencer GRCh37_chr3:118944135-118944307 Neighboring gene B4GALT4 antisense RNA 1 Neighboring gene beta-1,4-galactosyltransferase 4 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14625 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14626 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:118975541-118976279 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20294 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20295 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14627 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20296 Neighboring gene Rho GTPase activating protein 31 Neighboring gene ribosomal protein S26 pseudogene 21

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_100336.1 

    Range
    101..625
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    119206874..119207398
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    121926590..121927114
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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