MST1L macrophage stimulating 1 like (pseudogene) [Homo sapiens (human)] - Gene

Summary

Official Symbol: MST1Lprovided by HGNC
Official Full Name: macrophage stimulating 1 like (pseudogene)provided by HGNC
Primary source: HGNC:HGNC:7390
See related: Ensembl:ENSG00000186715 AllianceGenome:HGNC:7390
Gene type: pseudo
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: BRF-1; MSPL7; MST1P; MSTP7; MSTP9; MSPL-7; MST1P7; MST1P9; D1F15S1A
Summary: Predicted to enable serine-type endopeptidase activity. Predicted to be involved in positive regulation of mammary gland epithelial cell proliferation and regulation of macrophage chemotaxis. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in kidney (RPKM 17.3), duodenum (RPKM 15.5) and 12 other tissues See more
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Genomic context

Location:: 1p36.13

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	1	NC_000001.11 (16757120..16764480, complement)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	1	NC_060925.1 (16566467..16570445, complement)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	1	NC_000001.10 (17083615..17090975, complement)

Chromosome 1 - NC_000001.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The shortest intron sequence is 30 bp long and belongs to the MST1L gene of H. sapiens encoding for the putative macrophage stimulating 1-like protein.
Title: Identification of minimal eukaryotic introns through GeneBase, a user-friendly tool for parsing the NCBI Gene databank.

Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

MST1_945 (e-PCR)
- UniSTS:277510

RH92673 (e-PCR)
- UniSTS:89659

AL034008 (e-PCR)
- UniSTS:93522

D3S4175 (e-PCR)
- UniSTS:71580

D3S4175 (e-PCR)
- UniSTS:71581

RH102089 (e-PCR)
- UniSTS:96423

SHGC-132146 (e-PCR)
- UniSTS:170674

Other Names

brain-rescue-factor-1
macrophage stimulating 1 (hepatocyte growth factor-like) pseudogene 9
macrophage stimulating, pseudogene 7
macrophage stimulating, pseudogene 9
putative macrophage stimulating 1-like protein
putative macrophage-stimulating protein MSTP9

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
NOT enables endopeptidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables receptor tyrosine kinase binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in proteolysis	IEA Inferred from Electronic Annotation more info
involved_in regulation of receptor signaling pathway via JAK-STAT	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

NR_171546.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AL021920

Related

ENST00000442552.7

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000001.11 Reference GRCh38.p14 Primary Assembly

Range

16757120..16764480 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

NW_025791756.1 Reference GRCh38.p14 PATCHES

Range

764859..772220

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GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

NC_060925.1 Alternate T2T-CHM13v2.0

Range

16566467..16570445 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NG_001235.1: Suppressed sequence

Description

NG_001235.1: This RefSeq was suppressed permanently because the MSTP7 and MSTP9 are no longer considered to be distinct loci.
NM_001271733.1: Suppressed sequence

Description

NM_001271733.1: This RefSeq was removed because it is now thought that this gene does not encode a protein.
NR_002729.2: Suppressed sequence

Description

NR_002729.2: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.