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CCND2-AS1 CCND2 antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 103752584, updated on 10-Oct-2023

Summary

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Official Symbol
CCND2-AS1provided by HGNC
Official Full Name
CCND2 antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:49398
See related
Ensembl:ENSG00000255920 AllianceGenome:HGNC:49398
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CCND2-AS2
Expression
Ubiquitous expression in adrenal (RPKM 4.8), brain (RPKM 4.4) and 25 other tissues See more
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Genomic context

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Location:
12p13.32
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (4248767..4276184, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (4255526..4282943, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (4357933..4385350, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124900317 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:4226148-4227142 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5819 Neighboring gene ribosomal protein L18 pseudogene 9 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:4243897-4244502 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5820 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:4256026-4256526 Neighboring gene CRISPRi-validated cis-regulatory element chr12.200 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4146 Neighboring gene uncharacterized LOC105369612 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5822 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:4311299-4312200 Neighboring gene Sharpr-MPRA regulatory region 8601 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:4314426-4315336 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5823 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4147 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4148 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4149 Neighboring gene ReSE screen-validated silencer GRCh37_chr12:4381043-4381234 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4150 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4151 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4152 Neighboring gene ReSE screen-validated silencer GRCh37_chr12:4387997-4388189 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:4389371-4390328 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5824 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:4402781-4403282 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:4403283-4403782 Neighboring gene cyclin D2 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:4429971-4430624 Neighboring gene ribosomal protein S15 pseudogene 7 Neighboring gene TP53 induced glycolysis regulatory phosphatase Neighboring gene fibroblast growth factor 23

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. LncRNA CCND2-AS1 promotes proliferation, migration, and invasion in papillary thyroid carcinoma. Xia E, et al. Biochem Biophys Res Commun, 2018 Feb 5. PMID 29366479
  2. Highly expressed lncRNA CCND2-AS1 promotes glioma cell proliferation through Wnt/β-catenin signaling. Zhang H, et al. Biochem Biophys Res Commun, 2017 Jan 22. PMID 27923660
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Other Names

  • CCND2 antisense RNA 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_125790.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC006122
    Related
    ENST00000539135.1

  2. NR_149145.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC006122
    Related
    ENST00000646245.2

  3. NR_149146.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC006122

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    4248767..4276184 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    4255526..4282943 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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