Gene expression changes in primary mouse fibroblasts in the absence of ASCIZ - - GEO DataSets

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Gene expression changes in primary mouse fibroblasts in the absence of ASCIZ

(Submitter supplied) In order to identify potential transcriptional targets of ASCIZ, we performed a microarray analysis of three wildltype and ASCIZ(ATMIN/ZNF822)-deficient littermate single-passage MEF cultures. Only 22 and 25 genes were found to be down- or upregulated in the KO, respectively, by >1.5-fold (p<0.05). The most severely downregulated gene was Dynll1, which was confirmed by Norhtern and Western blot in mulitple embryonic tissues.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6887
6 Samples

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Accession:: GSE30417

ID:: 200030417

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