GEO DataSets

Analysis of WBCs from pediatric B cell precursor (BCP) acute lymphoblastic leukemia (ALL) patients with early, late, or no relapse. For patients with relapsed BCP-ALL, early relapses fare worse than later relapses. Results provide insight into the molecular basis of early relapses in BCP-ALL.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 3 disease state sets

Platform:

GPL570

Series:

GSE13576

197 Samples

Download data: CEL

(Submitter supplied) Gene expression analysis identified a specific signature of differentially expressed genes discriminating TTLshort and TTLlong phenotypes. Gene expression signatures of xenografted leukemia samples with different TTL phenotypes were analyzed on cohorts of pediatric BCP-ALL patients.

Organism:

Homo sapiens

Type:

Expression profiling by array

Datasets:

GDS4206 GDS4779

Platform:

GPL570

209 Samples

Download data: CEL

Analysis of xenograft leukemia samples from NOD/SCID mice transplanted with leukemia cells from patients with pediatric BCP-ALL. The xenograft samples displayed short or long “Time To Leukemia” (TTL). Results provide insight into molecular mechanisms underlying the distinct TTL phenotypes.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state sets

Platform:

GPL570

Series:

GSE13576

12 Samples

Download data: CEL

(Submitter supplied) Purpose: In childhood acute lymphoblastic leukemia (ALL), approximately 25% of patients suffer from relapse. In recurrent disease, despite intensified therapy, overall cure rates of 40% remain unsatisfactory and survival rates are particularly poor in certain subgroups. The probability of long-term survival after relapse is predicted from well-established prognostic factors, i. e. time and site of relapse, immunophenotype and minimal residual disease. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL96

60 Samples

Download data: CEL, EXP

(Submitter supplied) Leukemic cells from either peripheral blood or bone marrow were obtained from 6 patients with acute lymphocytic leukemia. These cells were used to generate mouse xenografts and a comparison was made between those two sample sources.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6884

10 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by high throughput sequencing

Platforms:

GPL11154 GPL6244

22 Samples

Download data: CEL

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL96

113 Samples

Download data: CEL

(Submitter supplied) Gene expression profiles were analyzed from 60 children with first bone marrow relapse. Genes and pathways differentiating early vs. late relapse were identified. Signatures predicting early response to therapy were also identified. Keywords: ordered

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL96

59 Samples

Download data: CEL

(Submitter supplied) 35 paired samples from initial diagnosis and first marrow relapse. Genes and pathways differentiating diagnosis and relapse were identified. Potential therapeutic targets were also identified. Keywords: paired

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL96

70 Samples

Download data: CEL