Similar studies for GEO DataSets (Select 3626) - GEO DataSets

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Items: 3

Select item 36261.

Macrophage migration inhibitory factor depletion effect on kidney cell line

Analysis of HEK293 kidney cells depleted for the macrophage migration inhibitory factor (MIF). MIF depletion in HEK293 cells result in G(0)/G(1) cell cycle arrest. Results provide insight into the molecular mechanisms underlying this cell cycle arrest.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 protocol sets

Platform:: GPL6102
Series:: GSE10241
4 Samples

Download data: TXT

DataSet

Accession:: GDS3626

ID:: 3626

Select item 2000102412.

A Global Genomic View of MIF Knockdown Cell

(Submitter supplied) siRNA-mediated knockdown of MIF expression in HEK293 cells resulted in inhibition of cell proliferation and cell cycle progress. The microarray study of MIF KD cells reveald knockdown of MIF would lead to extensive changes in gene expression profiles which may elucidate the molecular mechanism of MIF siRNA-mediated inhibition of cell cycle and cell proliferation. Keywords: The whole-genome expression analysis in MIF knockdown cells and the control cells

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3626
Platform:: GPL6102
4 Samples

Download data: TXT

Series

Accession:: GSE10241

ID:: 200010241

Select item 2000834763.

Transcriptomic profiling of human coronary artery endothelial cells under laminar shear stress (LS), oscillatory shear stress (OS) and static culture (ST)

(Submitter supplied) Aim: To survey the alteration of endothelial transcriptome under different types of shear stress and find novel shear stress-sensitive protein-coding genes as well as non-coding RNAs as potential therapeutic targets for the treatment of atherosclerosis Method: After exposed to LS, OS and ST for 24 hours (n=4, respectively), ECs were harvested by scraping, and RNA was isolated and purified. Double-stranded cDNA was generated from 100 to 150 ng of total qualified RNA using selective priming and prepared for the final library. more...