GEO DataSets

Analysis of neutrophils from healthy males before and after 30 minutes of aerobic exercise. The number of circulating neutrophils increases after exercise. Results provide insight into the molecular response of these immune cells to exercise.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 12 individual, 2 protocol sets

Platform:

GPL570

Series:

GSE8668

24 Samples

Download data: CEL

(Submitter supplied) Relatively brief bouts of exercise alter gene expression in peripheral blood mononuclear cells (PBMCs), but whether or not exercise changes gene expression in circulating neutrophils (whose numbers, like PBMCs, increase) is not known. We hypothesized that exercise would activate neutrophil genes involved in apoptosis, inflammation, and cell growth and repair, since these functions in leukocytes are known to be influenced by exercise. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3073

Platform:

GPL570

24 Samples

Download data: CEL

(Submitter supplied) Analysis of peripheral blood mononuclear cells (PBMCs) separated from whole blood of healthy male subjects - prior to onset of exercise - immediately following the end of exercise and - immediately following 1 hour of recovery from exercise Keywords: other

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS962

Platform:

GPL96

15 Samples

Download data: CEL

Peripheral blood mononuclear cells (PBMC) were isolated from blood samples taken from healthy male subjects before, immediately after, and 60 minutes after 30 minutes of exercise. Brisk activation and deactivation of genes associated with stress, inflammation, and tissue repair observed.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 time sets

Platform:

GPL96

Series:

GSE1140

15 Samples

Download data: CEL

(Submitter supplied) We compared PBMC genomic response to exercise in both early (EB) and late-pubertal boys (LB) Keywords: stress response

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

40 Samples

Download data: CEL

(Submitter supplied) We compared PBMC genomic response to exercise in both early (EG) and late-pubertal girls (LG) Keywords: stress response

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

40 Samples

Download data: CEL

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL9454 GPL570

65 Samples

Download data: CEL

(Submitter supplied) White blood cells (WBCs) express tens of thousands of genes. Their expression levels are modified by genetic and external factors. The purpose of the present study was to investigate the effects of acute exercise on gene expression profiles (GEPs) of WBCs and to identify suitable genes which may serve as surrogate markers for monitoring exercise and training load. Five male probands performed an exhaustive treadmill test (ET) at 80% of their VO2max, and a moderate treadmill test (MT) at 60% VO2max for exactly the same time one to two week later. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS2310

Platform:

GPL571

20 Samples

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Analysis of white blood cells (WBCs) from 5 males following exhaustive or moderate exercise. Results provide insight into the effects of exercise at the molecular level and the feasibility of using gene expression profiles of WBCs to monitor exercise and training load.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 5 individual, 4 time sets

Platform:

GPL571

Series:

GSE3606

20 Samples

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(Submitter supplied) Exercise leads to a rapid change in the profile of gene expression in circulating neutrophils. We hypothesized that miRNA expression in circulating neutrophils would also be affected by brief exercise.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL7731

22 Samples

Download data: TXT

(Submitter supplied) It is unknown how soon the diaphragm begins to start the process of atrophy following the start of MV. We hypothesized that genes responsible for maintaining diaphragmatic contractile function, stress response, energy transduction would be altered over the course of a 5 hour cardiothoracic surgery.

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4308

Platform:

GPL570

10 Samples

Download data: CEL

Analysis of paired diaphragm biopsies from 5 patients during cardiothoracic surgery: the 1st as soon as diaphragm was exposed, the 2nd as late in surgery as possible (4.9 ± 1.8 hrs between biopsies). Results provide insight into diaphragm muscle biology after prolonged cardiothoracic procedures.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 5 age, 5 individual, 2 specimen sets

Platform:

GPL570

Series:

GSE19533

10 Samples

Download data: CEL

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array; Expression profiling by array

Platforms:

GPL570 GPL10850

46 Samples

Download data: CEL, TXT

(Submitter supplied) We tested the hypothesis on the mechanisms responsible for the early control of NK cell function by identifying a discrete set of genes in circulating NK cells that were altered by exercise. Exercise leads to a rapid change in the profile of gene expression in NK cells.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

24 Samples

Download data: CEL

(Submitter supplied) Exercise leads to a rapid change in the profile of gene expression in NK cells. We hypothesized that microRNA expression in circulating NK cells would also be affected by brief exercise.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL10850

22 Samples

Download data: TXT

(Submitter supplied) vastus lateralis biopsies were obtained from healthy subjects, either young adults (20-29 yr old) or older (65-75 yr old) Keywords = muscle Keywords = aging Keywords: other

Organism:

Homo sapiens

Type:

Expression profiling by array

Datasets:

GDS287 GDS288

Platforms:

GPL96 GPL97

30 Samples

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Comparison of gene expression in vastus lateralis skeletal muscle biopsies in healthy young (21-27 year old) and older (67-75 year old) men.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 age sets

Platform:

GPL97

Series:

GSE362

15 Samples

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Comparison of gene expression in vastus lateralis skeletal muscle biopsies in healthy young (21-27 year old) and older (67-75 year old) men

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 age sets

Platform:

GPL96

Series:

GSE362

15 Samples

Download data

(Submitter supplied) Hypersensitivity reactions to medications constitute a growing problem in the clinical practice. In order to study the molecular basis underlying the pathogenesis of non-immediate hypersensitivity reactions to drugs, we characterized the gene expression profiles of PBMCs isolated from patients during the acute phase and upon resolution of the clinical symptoms using a cDNA array technology. Eighty five genes were found to be differentially expressed during the acute phase of drug-induced delayed hypersensitivity reactions. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL7328

26 Samples

Download data: TXT

(Submitter supplied) We used gene microarray analysis to compare the global expression profile of genes involved in adaptation to exercise training in skeletal muscle from chronically strength/resistance trained (ST), endurance trained (ET) and untrained control subjects (Con). Resting skeletal muscle samples (~100mg) were obtained from the vastus lateralis of 20 subjects (Con n=7, ET n=7, ST n=6; trained groups >8 years specific training). more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6042

21 Samples

Download data: GPR