Conserved Protein Domain Family
pyrC

?
PRK09357: pyrC 
dihydroorotase; Validated
Links
?
Statistics
?
PSSM-Id: 236479
Aligned: 267 rows
Threshold Bit Score: 351.42
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
189346779   2 STIFQRAHLLNPAeNLDATGSIRIDGSGFIEsvslgs--admphnDDDRVIDLDGKLLVPGLFDMHCHFREPGQEYKETL 79 
238925256   1 -MIIKNGIIADPAsGLYEHMDILVKDGKIVKispdiscasdaaatEKEEIIDASGMIVGPGLIDTHVHFRDPGFTYKEDI 79 
170288396   1 ------MRIYDPFrKKWiee-------------------------eieTPFPSKGLVATFPFVDLHVHVRLNGGEDYSSL 49 
15643103    1 ------MRIYDP-----------FRKKWIEE--------------EIETPFPSKGLVATFPFVDLHVHVRLNGGEDYSSL 49 
222099308   1 ----MDGKIT----GKEFGGKSVRIYDPFRKkwie---------eeieTPFPSKGLVATFPFVDLHVHVRLNGGEDYSSL 63 
148269721   1 ------MRIYDPFrKKWiee-------------------------eieTPFPSKGLVATFPFVDLHVHVRLNGGEDYSSL 49 
281412395   9 EFGGKNVRIYDPFrKRWiee-------------------------eieTPFPSKGLVATFPFVDLHVHVRLNGGEDYNSL 63 
217076622   1 ------MKYISVKvYDPYQKKLFYEEISLPK------------------NIHYENLVVVPTFFDFHTHVRL--LEDQEDY 54 
150020170     --------------------------------------------------------------------------------    
154249160   1 ---MESLKVYNIYkGKIEDFELKDIELDFPE-----------------NPATTNGLLLSPPFVDLHTHVRLIDGEDYDSL 60 
189346779  80 ETGSSAAAAGGYTGVALMPNTRPVIDSPLGVAYIRHHSALLP-VDLEVIGAMTVESRGETLAPFGKFRS--YGVTAISDD 156
238925256  80 HTGSLAAAKGGFTTVVCMANTKPTVDNVDTLKDNLTRGKQEK-IRMYQAAAISHSLKGQDEVDMAALKE--AGACGFTDD 156
170288396  50 EE---ASLVGGFFKVVVQPNTKPLIDSKEVLERHLDLSKNRAvEFLFAVSP------------FGSIEAegERVVGFSTD 114
15643103   50 EE---ASLVGGFFKVVVQPNTKPLIDSKEVLERHLDLSKNRAvEFLFAVSP------------FGSIEAegERVVGFSTD 114
222099308  64 EE---ASLVGGFFKVVVQPNTKPLIDSKEVLERHLDLSKNRAvEFLFAVSP------------FGSIEAegERVVGFSTD 128
148269721  50 EE---ASLVGGFFKVVVQPNTKPLIDSKEVLERHLDLPKNRAvEFLFAVSP------------FGSIEAegERVVGFSTD 114
281412395  64 EE---ASLVGGFFKMVVQPNTKPPIDNKEVLERHLDLSRNKAvEFLFTVSP------------FGSIEAegERVVGFSTD 128
217076622  55 ESLKKACIAGGFSEVLIQPNTKPRLENSNVHEK-HKKLSENPyVKFYR----TTSF-------FGFQEPnnIDILCYSTD 122
150020170   1 --------------MLIQPNTNPILENKQVHKYHEKLVADSH-VRFYRTTSLFGTQKPS------------DNILCYSTD 53 
154249160  61 T---KAAVVGGFLIVNLQPNTKPVIDSLDVLNEHIKLSEDKIvLYNYTVSLF-----GKVEDLYDANSQfgEKITGYSTD 132
189346779 157 GTAIQNTQIMRLAFEYASNFDLLIIQHCEDKTLTKG-GVMNESHFSTILGLKGIPDVAEAIIVSRDLQLMrylqqhklhd 235
238925256 157 GIPLTNAAFCYRAMQNAAKLDMPISLHEEDPAFIKN-NGINHGKISDALGIYGSPSIAEEALVARDCLLA---------- 225
170288396 115 GIEYDYPTLVETMKKKKKALWFDHSQMYEVDGIFYE---------GAPLPFQKRPRSNEAIAIARTVLTG---------- 175
15643103  115 GIEYDYPTLVETMKKKKKALWFDHSQMYEVDGIFYE---------GAPLPFQKRPRSNEAIAIARTVLTG---------- 175
222099308 129 GIEYDYPTLVETMKKKKKAL------WFDHSQMYEVdGIFYEG---APLPFQKRPRSNEAIAIARTVLTG---------- 189
148269721 115 GIEYDYPTLVETMKKKKKALWFDHSQMYEVDGIFYE---------GAPLPFQKRPRSNEAIAIARTVLTG---------- 175
281412395 129 GIEYDYHALVESMKKRKKALWFDHSQMYEVDGIFYE---------GTPLPFPKRPRSNEAIAITRTVLTG---------- 189
217076622 123 GIEYNYNELVENFSKKKPHLLLDHSQMFEHPGIFYK----------KIENLPKRPVTNEAVAVARTILTG---------- 182
150020170  54 GIKYTYNDLVENFSRKKPALVLDHSQLFEHEGIFYK----------EILDIPKRPITNEAIAIARTVLTG---------- 113
154249160 133 GIYYYSEDLVDGFKNKKPYLLFDHSQLHELSGDFYI---------GTNLPNSIRTYSNESIAIFRTVMTG---------- 193
189346779 236 PLNQ-PRYHVAHISTGAALDLVRQAKLDGLQVTCEVTPHHFTLSDEdlFLAEAKGNFIMKPPLGSAENMQALIDAIADGT 314
238925256 226 LRSG-ADVVIQHISSGVSVDIVRTYKKLGARLHAEATPHHFTLTED--AVLEHGTLAKMNPPLRTEADRQKIIEGLIDGT 302
170288396 176 LEYGfERFHIQHVTTKYSVEVISFLKNLA-KVSCEVTPHHLFFCYE--DIK--NTNFKINPPLGSPEDRRALIEAVKKDV 250
15643103  176 LEYGfERFHIQHVTTKYSVEVISFLKNLA-KVSCEVTPHHLFFCYE----DIKNTNFKINPPLGSPEDRRALIEAVKKDV 250
222099308 190 LEYGfERFHIQHVTTKYSVEVISFLKNLA-KVSCEVTPHHLFFCYE--DIK--NTNFKINPPLGSPEDRRALIEAVKKDV 264
148269721 176 LEYGfERFHIQHVTTKYSVEVISFLKNLA-KVSCEVTPHHLFFCYE--DIK--NTNFKINPPLGSPEDRRALIEAVKKDV 250
281412395 190 LEYGfERFHIQHVTTKYSVEVISFLKNLA-KVSCEVTPHHLFFCYE--DIK--NTNFKINPPLGSPEDRKALIEAVKEDV 264
217076622 183 IEFGfKDFHIQHISSIYTLEMIKFLKKYA-NITCEVTPHHLLLTNE--HIK--NSNFKINPPLADQQTREFLIEAVKNND 257
150020170 114 FEFGfKDFHIQHISTTYSLEMIEFLKKCA-NITCEVTPHHLLISNE--EIL--NPNFKINPPLCDKKTIEILKDAVKTNK 188
154249160 194 IEFGfNKFHIQHVSTLQSIEVITYLKKYA-QITCEVTPHHVFFTPD----MISSPNQKINPPISK--YRDELIKAVRSGI 266
189346779 315 IDAIATDHAPHAAHEKDCPPDQAAFGITGLETAVGLTLTELVSKNVITMQRAIEMLSVNPRKIMN---------LAPVHF 385
238925256 303 IDLIATDHAPHSTEEKSKPVTEAPSGIIGLETSLALGITSLVKPGHLSMLELLEKMTINPARLYH---------MPYGTI 373
170288396 251 IDVLATDHAPHHEKPD--DFLTAPYGSTSIEIAFPAYYTA-----LGDLELVVKKLTKKPLEVLG---------VEA--- 311
15643103  251 IDVLATDHAPHHEKPDD--FLTAPYGSTSIEIAFPAYYTA-----LGDLELVVKKLTKKPLEVLG---------VEA-RL 313
222099308 265 IDVLATDHAPHHEKPD--DFLTAPYGSTSIEIAFPAYYTA-----LGDLELVVKKLTKKPLEVLG---------VEA--- 325
148269721 251 IDVLATDHAPHHEKPD--DFLTAPYGSTSIEIAFPAYYTA-----LGDLELVVKKLTKKPLEVLG---------VEA--- 311
281412395 265 IDVLATDHAPHHEKPD--DFLTAPYGSTSIEIAFPAYYTA-----LGDLELVVEKLTKKPLEVLG---------VEA--- 325
217076622 258 IDILATDHAPHPDKKN--DFEKAPYGTSNIEIAFSAFYTA-----IEDLMIVINKLCDTPRRRLK---------IKP--- 318
150020170 189 IDILATDHAPHPEKPA--DYRKAPYGTSNIEIAFSAFYTA-----LNDVYLVTDKLCYAPRKRLG---------ISY--- 249
154249160 267 IDTFATDHAPHPEKPVR--YEDAPYGSSHIEVAFSVYLTI-----FEDIELVLKNLTVKPLKILGksyadfnmnFPS--- 336
189346779 386 RAGEMANMTIIDPEvEWTVTKDDMKSRSQNTPFIGRRLKGRAVGIYHKGALLENR 440
238925256 374 SEGAAADFVIFDPDeKWV--PCEYASKSSNTPFTGMELTGKVKYTVCGGNVIYSD 426
170288396 312 -RLTEDTLVFIDPEaEFIVDAKKFKSKGKNSMFDGVRLKGKVVALKLKGRWVMID 365
15643103  314 TE---DTLVFIDPEaEFIVDAKKFKSKGKNSMFDGVRLKGKVVALKLKGRWVMID 365
222099308 326 -RLTEDTLVFIDPEaEFIVDAKKFKSKGKNSMFDGVRLKGKVVALKLKGRWVMID 379
148269721 312 -RLTEDTLVFIDPEaEFIVDAKKFKSKGKNSMFDGVRLKGKVVALKLKGRWVMID 365
281412395 326 -HLTEDTLVFIDPKaEFIVDVKKFKSKGKNSMFDGVRLKGRVVALKLKGRWVMID 379
217076622 319 -KFDSENFVVVDLNqEFIVDSKKFYSKGKNCAFDGMKLKGKVVGVKINGKWGFWN 372
150020170 250 -KFTSDNLVIVDLNqEFTVESKRFFSKGKNCAFDGMKLKGKIIGVKINGKWGYWN 303
154249160 337 -----DA-VLIDTKaEYIVDGNNFYSKGKNCAFNGYKVKGKVLGVRRNGRWVYWD 385
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap