5H2D_A 44 SLWSVLKsmVGKDMTRMTLPVSFNEPTSLLQ-RVAEDLEYADLLNQAASfeD-STLRLLYVAIFTVSSYASTVKRVAKPF 121 Kluyveromyces l... XP_004941496 378 ILLKQLR--PGMDLSRVVLPTFILEPRSFLN-KLSDYYYHADLLSQAALe-DdPYSRMKQVLRWYLSGFYKKPkGIKKPY 453 chicken XP_005997641 373 TLLKQLR--PGMDLSRVVLPTFILEPRSFLD-KLSDYYYHADLLSQAALe-EsAYCRMKQILRWYLSGFYKKPkGLKKPY 448 coelacanth XP_007228135 346 TLLKQLR--PGMDLSKVVLPTFILEPRSFLD-KLSDYYYHASLLSQAVLe-EsPYCRMKQVLRWYLSGFYKKPKGLKKPY 421 Mexican tetra CAG01146 372 gllKQLR--PGMDLSKVVLPTFILEPRSFLD-KLADYYYHADLLSQAVQe-EsAYGRMKQVLRWYLSGFYKKPkGLKKPY 447 spotted green p... EDO35914 246 ALLKQVK--PGMDLSRVTLPTFILEPRSFLD-KLSDFYYHTDILSRAACe-EnPYSRMKEVIRWYLSGFYKKPkGLKKPY 321 starlet sea ane... XP_653552 45 EILKQLR--PGMSLERITMPTHVMEPRSLLE-KLTDYFTHLDLVNAAANa-PtAEERMVKLVQFFLSGFYITPkACKKPY 120 Entamoeba histo... EGC29297 19 allkQVK--LNKEIKHMVLPSFLLQTRSTLE-SFTDMYSYIDELYRVNEi-EnEQDRFVQFVKFYLSGWHTRPkGIKKPF 94 Dictyostelium p... XP_004366315 73 sfISQLG--IGQELTKVSMPSMFLMPYSILElAGARYLKYFHLLSAVSSe-PdQARRMAIVIQYFLACIRDG-NFQRKPY 148 Cavenderia fasc... EFA80092 33 sfISQLG--IGQELTKVSMPSIFLMPYSILElAASRYLKYFHLLSGALYe-TdPSRRMAIVIQYFLSCIRDG-NFTKKPY 108 Heterostelium a...
5H2D_A 122 NPLLGETFEY-SRp--------dKSYR----------FFTEQVSHHPPISATWTES--PKWDFFGESFVD-SKFNGRSFD 179 Kluyveromyces l... XP_004941496 454 NPILGETFRC-CWfhpq---tnsHTF-----------YIAEQVSHHPPVSAFHVSNrkDGFCITGSILAR-SKFYGNSLS 517 chicken XP_005997641 449 NPILGETFRC-CWfhpk---tksHTF-----------YVAEQVSHHPPVSAFYVSNrkDGFCINGSILAR-SKFYGNSLS 512 coelacanth XP_007228135 422 NPILGETFRC-CWlhpq---tdsCTF-----------YLAEQVSHHPPISAFYVSNkkDGFCISGSILAK-SKFYGNSLS 485 Mexican tetra CAG01146 448 NPILGETFRC-CWlhpk---tdsCTF-----------YIAEQVSHHPPISAFHVCNrkDGFSISGSILAK-SKFYGNSLS 511 spotted green p... EDO35914 322 NPIIGEMFRC-YWqhp----qgsRTF-----------FVSEQVSHHPPVSAFYVSNrqDGFVINGAILAK-SKFYGNSSS 384 starlet sea ane... XP_653552 121 NPLLGEFYRT-SWsha----dgsKTF-----------FIAEQTSHHPPVSSIYACNrqAGWVGTGSLDFV-TTFNGLSAS 183 Entamoeba histo... EGC29297 95 NPVIGEQYEC-YWsenkeedlkgIDNlineknkdigvFKAEQISHHPPISSYVFYNtaRQILVNGNICPSyVKYLGNSAE 173 Dictyostelium p... XP_004366315 149 NALLGETHNCfIRypsaeedgktSTAR----------FIAEQVTHHPPLTAFHIETs-EGLTMDCNVQFS-AKFHMNSVS 216 Cavenderia fasc... EFA80092 109 NALLGENHQCfVRypaye-gegtTTAR----------FIAEQVSHHPPLSAFHISTt-DGIAMDCNVQFS-AKFHMNSVS 175 Heterostelium a...
5H2D_A 180 FKHLGLWYLTI----RpdsngKEELYTYKKPN--NQVVGILLGNPQVDNYGDVKIVNHNt--GD-YCMIHFKARG-Wr-s 248 Kluyveromyces l... XP_004941496 518 ALLDGKAKLMFl---N-----RGEDYIITMPY--AHCKGILYGTMTMELGGKVTID--CektNh-RAELEFKLKPlFggs 584 chicken XP_005997641 513 AILDGKARLTLl---S-----KEEEYIITMPY--AHCKGILYGTMTMELGGKVTIE--CektKy-RAELEFRLKPfLggs 579 coelacanth XP_007228135 486 AILDGKAKLLFl---Tr-----DEEYVITMPY--AHCKGILYGTMTLELGGKITIECEKt--KY-CAELEFKLKPfLgss 552 Mexican tetra CAG01146 512 AILDGKAKLLFl---N-----RDEEYVITMPY--AHCKGILYGTMTLELGGKVTIE--CqktKc-FSELEFKLKPfLgga 578 spotted green p... EDO35914 385 AILDGAATLALl---R-----FGEEYTMTMPY--AHCKGILIGTLTMELGGTVTIN--CektGy-KAEIEFKLKPfWkks 451 starlet sea ane... XP_653552 184 AGIQGLIKAKFt---K-----FDEDYEWNFPM--ALVTGIYIPPLTMEIGGVLNFV--CkqsGy-KAKVEFKTMSmFss- 249 Entamoeba histo... EGC29297 174 SHLQGILEFKFl---K-----FNEVYECSLPT--LGARGIVLGKLATFTSGEITIR--StsgGKfRASLEFLYKGlFgss 241 Dictyostelium p... XP_004366315 217 IVTSGDIIIKVpmreSdgepaHEEVYVIDKGLpdAIVKNVIFGTRSINWTDSVEIM--CqttNT-SATLHFDKNEfV--- 290 Cavenderia fasc... EFA80092 176 IVTAGSIIITIpv-rDgd-ktINESYIIDKGLpdALVKNVIFGTRSINWTDSVDIM--CqtsNT-SATLHFDKNEfV--- 247 Heterostelium a...
5H2D_A 249 SSAYEVKGEVY--N--AKG-GKEWIFGGRWNESVSAKkVLKPNSleemqvdelkh-------svthtssggpkYDGTRFN 316 Kluyveromyces l... XP_004941496 585 TSINQISGKIKs----G-E-EVLANLDGHWDGEVHINeLKNGNAevfwnptsevrkq----rlkrhivlfeeqTDFESER 654 chicken XP_005997641 580 SSVNQIVGKIKl----E-E-EVLASIEGHWDGEVFINeHKTGMSelfwnptieirqq----rlkrktvrleeqGEFESER 649 coelacanth XP_007228135 553 CNVNQVSGKIR--V--G-E-DVLATVEGHWDGEVLIYeKKTGQQevlwnptpevrkq----rlrrqvvqfdqqGLKESER 622 Mexican tetra CAG01146 579 CSVNQISGKILm----G-E-ELLATVDGHWDSEVFMYeKQSGQQetlwnptsdvrrs----rlkrqvvhidqqGEFESER 648 spotted green p... EDO35914 452 GESNYIAGKIIm----G-K-ETLCKIEGKWDGEIVITdLKASNAivnlfweptpeirs--qrlkrhlvdystqGEFESEK 523 starlet sea ane... XP_653552 250 sNYRQINGIIS--Dp-E-G-KPIYEINGRYDEELFITdKRTKEKksffkveelkkt-----keqrlvrefdklHPFESEK 319 Entamoeba histo... EGC29297 242 KNSNGVKGTLY--Ng---D-TPIFKIRGNWDKTVFIQpCNKNGDleqkenvlfdvkqlkksnevkfekpldqqPPNSSYH 315 Dictyostelium p... XP_004366315 291 ------KGDIYeyNeeKNEeEHHATLSGYLNSTVNI--EYFDTPassekskkksk--------kkskskkqfgPTDTVLF 354 Cavenderia fasc... EFA80092 248 ------KGDIYvyNeeAQEeEHHAYLNGYLCGVVNI--DYLEGEkmkkskkkh-----------sksrkhhynPTDTVLI 308 Heterostelium a...
5H2D_A 317 -----------------------VWHVnerpefpfnltkfaVTLnapqphllpwlpptdtrlrpdqrAMEEGRYDEAATE 373 Kluyveromyces l... XP_004941496 655 -----------------------LWQH--------------VTS-----------------------AINKGDQHKATQE 674 chicken XP_005997641 650 -----------------------LWQR--------------VTN-----------------------AISSRDQHGATQE 669 coelacanth XP_007228135 623 -----------------------LWKQ--------------VTI-----------------------AINTKDQNKATQE 642 Mexican tetra CAG01146 649 -----------------------LWQH--------------VTS-----------------------AIKDRDQLRATQE 668 spotted green p... EDO35914 524 -----------------------LWIG--------------VSN-----------------------AIKAADQEGATRE 543 starlet sea ane... XP_653552 320 -----------------------LFKR--------------VSD-----------------------AIIKNDQNLAMEE 339 Entamoeba histo... EGC29297 316 -----------------------LWEK--------------VTK-----------------------KINEHDDQGTAEE 335 Dictyostelium p... XP_004366315 355 eseklqpnhtlypkqtdpinslnVWKE--------------VTK-----------------------HIVANDMASSDVV 397 Cavenderia fasc... EFA80092 309 dtekleanqtqyprtndpmsslnIWKG--------------VTK-----------------------HIIDGDMAASDVA 351 Heterostelium a...
5H2D_A 374 KHRVEERQRSVRKKR--EEKnitYQQRWFKKEI--HpvTKcdywKFNGEYWK 421 Kluyveromyces lactis NRRL Y-1140 XP_004941496 675 KFVLEEEQRNAARERreNGTe--WKPLLFRHDSttD--Ew----RYKyedlr 718 chicken XP_005997641 670 KFVLEEAQRKGARERkeSSRd--WNPQLFQQDAtsN--Ew----QYKyadtr 713 coelacanth XP_007228135 643 KFVLEEAQRQEARER--GDRp--WKPHFFTLNPdtn------ewQYKHtdak 684 Mexican tetra CAG01146 669 KFVLEEAQRKEAKERgeKp----WSPRLFHRDPvtS--Dwtyrhldfrpwdp 714 spotted green pufferfish EDO35914 544 KFSLEEAQRKGHRERkeQGVd--WVPRLFERDPsaP--EAinrwVYKYrdvr 591 starlet sea anemone XP_653552 340 KFVLEEAQRTQRKLNdeKKVe--QERRLFDKQGsdH--Dw----KYKWENWN 383 Entamoeba histolytica HM-1:IMSS EGC29297 336 KKIIEDKQRREEAERveKGIh--WEPKDFQYRPhdG--EYkdtyYYKYipml 383 Dictyostelium purpureum XP_004366315 398 KKEIEDEQRKRLRATkeEEK---KERVYFkf------dEEqerwVFkgfptp 440 Cavenderia fasciculata EFA80092 352 KKEIEDEQRKRLRATkeDEK---KDRVYFrf------dDSlerwVFkgfptp 394 Heterostelium album PN500
Jiyao W et al.(2023). "The conserved domain database in 2023.",