Conserved Protein Domain Family
pheS

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PRK04172: pheS 
phenylalanine--tRNA ligase subunit alpha
Statistics
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PSSM-Id: 235239
Aligned: 95 rows
Threshold Bit Score: 517.077
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
15639957   15 VHKLHPLEIKVLKNC--AMDEIL--STSLLISRLGFKEGHANQAFSWLRAKRIIEEHQREQMRSFeLTPCGYAAASDGTA 90 
238620475   1 --MLSENEAKILFFL--KDLKRT--NSIEISTKIGIPESSVLSLIELLREKGYVKTETISEKYYV-LTEEGRKRKESGLP 73 
227828283   1 --MLSENEAKILFFL--KDLKRT--NSIEISTKIGIPESSVLSLIELLREKGYVKTETISEKYYV-LTEEGRKRKESGLP 73 
229585512   1 --MLSENEAKILFFL--KDLKRT--NSIEISTKIGIPESSVLSLIELLREKGYVKTETISEKYYV-LTEEGRKRKESGLP 73 
229579922   1 --MLSENEAKILFFL--KDLKRT--NSIEISTKIGIPESSVLSLIELLREKGYVKTEIISEKYYV-LTEEGRKRKENGLP 73 
15897061    2 ISMLSENEAKILFFL--KDLKKT--NSVELAIKMGIPESSVLSLIELLREKGYVKTEVKSEKHYV-LTEEGRKRKESGLP 76 
146304871   1 --MLSENEIKILDFL--KRRKES--TSQEIAEGTGLPLSSVFSIIATLESKGIVKVISEETRKVVrLTDEGKLRTEQGLP 74 
124027761   4 KIPVSESEHKLLELLvgRVEAGReyDTETLAELAGLDRSKVESLVRLLAEKGLVRLREETMEKYV-ATEEAKRYLREGFP 82 
118431822   2 EVTLSQGEYRLLKLM--AERGFRegTLEEASKILGVDKSSLASLSNLLAEKGVVEVEERVEEHYV-LTERGRDALERGLP 78 
302348138   3 AEQLSPGELELLKKL--ASLGEPl-DLEKSEELIGMPTSSAASLASLLEAKGLVKVDRRTVTRIL-LTERGEEALRNGLP 78 
15639957   91 EERMLTFLSsppsltaiadaaehlhprpplCNGLSLPELAHALtlaPKDVGSAFGILAQEGILRMdgEKRIHIVSP---- 166
238620475  74 EDILINSLN---------------------GQEKDLNEIKNTL---DEDFNIAISWAKRKGLIEI--KEGKVIPKVk--- 124
227828283  74 EDILINSLN---------------------GQEKDLNEIKNTL---DEDFNIAISWAKRKGLIEI--KEGKVIPKVk--- 124
229585512  74 EDILINSLN---------------------GQEKDLNEIKNTL---DEDFNIAISWAKRKGLIEI--KEGKVIPKVk--- 124
229579922  74 EDILINSLN---------------------GQEKDLNEIKNTL---DEDFNIAISWAKRKGLIEI--KEGKVIPKVk--- 124
15897061   77 EDILINTLN---------------------GQEKDLNEIKNIL---NKDFNIAISWAKRKGLIDI--KEGKVIPKVk--- 127
146304871  75 EDRLVTLLN---------------------GRPLKIQELRNAL---GKDFEIGFGWARRKGLITL--ENDTVIPKVs--- 125
124027761  83 EEKLVKILAg-------------------aGGEARLDELRNAM---GQELSIALANATRKGWVEVrgGRVRLVVDPs--- 137
118431822  79 EEKLVLFLAg-------------------rGGEASVEEVRRAL---GEEAGIALGQAARKGLVVI--AGGVVRLAVdqae 134
302348138  79 EERLLELLEa-------------------nNGSVAVDLARSSL---GNDFNIAIGVAIKAGYVKI--ANGMITLVDheg- 133
15639957  167 ---HVSDRMSLTRTLLQRAAarvaspseasdtppgtlfeselSDDERRVMERIAKKRgasdsLFKVSVRERVTFTFTPTA 243
238620475 125 --tYTSPEYLALLNLEKADI---------------------------NTINLLKKRG-----LIEEKERKIVNVELVKEP 170
227828283 125 --tYTSPEYLALLNLEKADI---------------------------NTINLLKKRG-----LIEEKERKIVNVELVKEP 170
229585512 125 --tYTSPEYLALLNLEKADI---------------------------NTINLLKKRG-----LIEEKERKIVNVELVKEP 170
229579922 125 --tYTSPEYLALLNLEKADI---------------------------NTINLLKKRG-----LIEEKERKIVNVKLVKEP 170
15897061  128 --tYMSSEYLALSNLERADS---------------------------NTINLLKKRG-----LIEEKERKIVSVELIKEP 173
146304871 126 --qYVSPEYTALKDLQAGKE------------------------PTGEVLEILLRRK-----LVEVKEEKMLRVQLLREV 174
124027761 138 --kAVAEERKLLEKLEIGER------------------------LQPSEFRLLRRRR-----LVERLAERRTIVVFPEAP 186
118431822 135 alkTITPLKKLLENVASGSK----------------------PTVGDELLREALSRG-----LIRREARRSIVLRLKVNP 187
302348138 134 fkaSVVNLKGGLRSIKEGGL------------------------VSEKIVDVLKGRG-----LVKVEQKNLVSIRLLPQG 184
15639957  244 RAVQEAlhtagltgNEI--GALTVECLKSGAWKTQHLRRYNVHIPPARIIPGRSNAYADFLEHIKDRLVALGFQEFDGPL 321
238620475 171 KE------------SEIgiSNLTREMIVSGEWKKYKLRKYNVEAFPPYYTISKKHYFREFLEKVKDIMISLGFKEINTGY 238
227828283 171 KE------------SEIgiSNLTREMIVSGEWKKYKLRKYNVEAFPPYYTISKKHYFREFLEKVKDIMISLGFKEINTGY 238
229585512 171 KE------------SEIgiSNLTREMIVSGEWKKYRLRKYNVEAFPPYYTISKKHYFREFLEKVKDIMISLGFKEINTGY 238
229579922 171 KE------------SEIgiSNLTREMIVSGEWKKYKLRKYNVEAFPPYYTISKKHYFREFLEKVKDIMISLGFKEINTGY 238
15897061  174 KE------------SEIgiSNLNRELIISGEWKKYKLKKYNVEAFPPYYTISKKHYFREFLEKVKDIMISLGFKEINTGY 241
146304871 175 ETRPAE-------------LYVTHEMLTTGSWREYEFKPYNVEANPPFFPIGKTHYFRDFIEKVKDLMVGLGFVEVSGDF 241
124027761 187 EKLLEQ--------VVVevGALTRDLIASGRWRTVRLRRYNVAAEPPRRRLGRLNFFVEFIEYLRDVMKEMGFQEVDDAP 258
118431822 188 AEALAR--------ARVeaAVLTRDMLKSGEWRRLRFKPYNVKAEPPRVLPARRHFLAEFIERLRDILRELGFREVRGPL 259
302348138 185 LSLATAk-------PSI--AKLSHELIATGKWREYTLRPYDVSAEPPLRMPARKHFFAEFIEELKDLMKEMGFVEVSGPL 255
15639957  322 VETDFWNADALFMPQFHPARDIHDVYYLKHPThAPTIP--EPFLSRVAATHERGADSGsLGWRYSFDRDFTRRLLLRSQG 399
238620475 239 IEMEFYNFDLLFQPQDHPAREIHDSFAVEGLGnIED----KELLSNVKEIHE-------KFWKYEWKQDITLRLMLRSQT 307
227828283 239 IEMEFYNFDLLFQPQDHPAREIHDSFAVEGLGnIED----KELLSNVKEIHE-------KFWKYEWKQDITLRLMLRSQT 307
229585512 239 IEMEFYNFDLLFQPQDHPAREIHDSFAVEGLGnIED----KELLSNVKEIHE-------KFWKYEWKQDITLRLMLRSQT 307
229579922 239 IEMEFYNFDLLFQPQDHPAREIHDSFAVEGLGnIED----KELLSNVKEIHE-------KFWKYEWKQDITLRLMLRSQT 307
15897061  242 IEMEFYNFDLLFQPQDHPAREIHDSFSVEGSGkIED----KDLLNNVKEIHE-------KFWKYEWKQDITLRLMLRSQT 310
146304871 242 VETEFFNFDMLFQPQDHPAREIHDSFVIEG---KGNLPg-SDLVRKVKEVHE-------KWWRYSWSEDNARRLVLRSQT 310
124027761 259 VELEFWNYDVLYQPQYHPARSPTDTFYLSNPS-RGELP--SELTPRVAEAHEKGLAGS-RGWRYRWSQELAARLILRSHT 334
118431822 260 VELELFNFDVLFQAQDHPAREIHDSLWIKSPR-RGDLSgySDLVERVASVHE-------RGWKYRWSPEVASRYILRSQT 331
302348138 256 VELELFNFDALFQPQDHPAREMHDTFWPDLPP--ADLSdyADIVARVKYEHE-------HGWGYQWDGSVASRRILRSQT 326
15639957  400 TALSARHLP-TAHIPGKYFGIARCFRHDQVDATHLADFYQTEGIVLGTDVNVCTLLGMLKILATEIaGAQEVRYVGGYFP 478
238620475 308 TATTARVLAsRPKAPQKVFTLGKVFRPDAIDATHLIEFHQLDGVIIDDNFTFRELLGVLKEIFYRL-GIKEIKFKPAYFP 386
227828283 308 TATTARVLAsRPKAPQKVFTLGKVFRPDAIDATHLIEFHQLDGVIIDDNFTFRELLGVLKEIFYRL-GIKEIKFKPAYFP 386
229585512 308 TATTARVLAsRPKAPQKVFTLGKVFRPDAIDATHLIEFHQLDGVIIDDNFTFRELLGVLKEIFYRL-GIKEIKFKPAYFP 386
229579922 308 TATTARVLAsRPKAPQKLFTLGKVFRPDAIDATHLIEFHQLDGVIIDDNFTFRELLGVLKEIFYRL-GIKEIKFKPAYFP 386
15897061  311 TATTARVLAsRPKAPQKVFTLGKVFRPDAIDATHLIEFHQLDGVIIDNNFTFKELLGVLKEIFYRL-GIKEVKFKPAYFP 389
146304871 311 TAVTARVLS-GAPKRIRAFTIGKVFRPDSIDATHLIEFHQMDGLVIEEDFTFRDLLSTLRDIFQGL-GVKQVKFKPGYFP 388
124027761 335 TAVSARVLAsKPRPPFRFFTIGRVYRVETIDPRHLPEFHQLDGIASEDGVSLRWLLGLLAEFLERI-GIREYKFRPAYFP 413
118431822 332 TAVSARILAtRPNPPARFFTVGKVFRSDAVGPTRLPEFHQLDGIEGDEGYTFRDLLGRLDEIASML-GL-KLKFKPAYFP 409
302348138 327 TAVTIRVLAsRPRPPIRFFTIDKVFRADPVDATHLSDFHQLDGIMGWKDFTFRDLLGFLSEFGKRL-GL-ELKFKPAYFP 404
15639957  479 FTEPSIELHALHPALGWFELGGAGLLRPEVTDPLGVHVPVMAWGLGVDRMALLALGISDVRELFSPDIESVRLRV 553
238620475 387 FTEPSVEAYGYLEKLGWVEMCGAGLLRPEILSSVGIDKIAGAWGIGIERLAMSFLNISDIRLLYSNNIEYIRDMK 461
227828283 387 FTEPSVEAYGYLEKLGWVEMCGAGLLRPEILSSVGIDKIAGAWGIGIERLAMSFLNISDIRLLYSNNIEYIRDMK 461
229585512 387 FTEPSVEAYGYLEKLGWVEMCGAGLLRPEILSSVGIDKIAGAWGIGIERLAMSFLNISDIRLLYSNNIEYIRDMK 461
229579922 387 FTEPSVEAYGYLEKLGWVEMCGAGLLRPEILSSVGIDSIAGAWGIGIERLAMSFLNISDIRLLYSNNIEYIRDMK 461
15897061  390 FTEPSVEAYGYLEKLGWVEMCGAGLLRPEILSSVGIDSTAGAWGIGIERLAMSFLNISDIRLLYSNNIEYIRDTK 464
146304871 389 FTEPSVEVYGFIEGLGWVEMAGAGLLRKEVTEPAGVFSPAGAWGIGIDRLAMLFLGVKDIRDLYSLDIEYLRSRR 463
124027761 414 FTEPSVEAYVRV-RDQWLEVLGAGLFRPEMLAALGIDYPVAAWGMGIERLAMALYDLTDIRQLYSHDVEFLENIP 487
118431822 410 FTEPSVEGYVKLPNGRWLELFGAGMFRPEVLEAVGVDYPVGAWGFGIERLAMAFYGVSDIRKLYTRNVDEVREMR 484
302348138 405 FTEPSVEGYARI-GSSMVEVFGAGLFRPEVLRIAGVDYQVGAWGMGVERLALARFGLHDVRDLYSKDYDFLRSFK 478
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