Conserved Protein Domain Family
CRM1

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COG5101: CRM1 
Importin beta-related nuclear transport receptor [Nuclear structure / Intracellular trafficking and secretion]
Statistics
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PSSM-Id: 227432
Aligned: 3 rows
Threshold Bit Score: 1551.06
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
399300      1 MEGILDFSNDLDIALLDQVVSTFYQGSGVQQKQAQEILTKFQDNPDAWQKADQILQFSTNPQSKFIALSILDKLITRKWK 80   baker's yeast
19074824   35 MEQILELDKDLNIEVFDKVVTNANCPDNRKKEEAERILLKFKELPNSWTKVDYILNNSKLQESHYVALQLLESIIKTKWS 114  Encephalitozoon c...
19114840    1 MEGILAFDRELDVALLDRVVQTFYQGVGAEQQQAQQVLTQFQAHPDAWSQAYSILEKSEYPQTKYIALSVLDKLITTRWK 80   fission yeast
399300     81 LLPNDHRIGIRNFVVGMIISMCQDDEVFKTQKNLINKSDLTLVQILKQEWPQNWPEFIPELIGSSS-SSVNVCENNMIVL 159  baker's yeast
19074824  115 LFDEGMKQGLRMYVFQLVIEKS---KARDKENYVLQELNTILIEIAKKDWPRRWPTFITDLINVSQgISMEVCRNSLNIL 191  Encephalitozoon c...
19114840   81 MLPKEQRLGIRNYIVAVMIKNSSDETVLQQQKTFLNKLDLTLVQILKQEWPHNWPNFIPEIVQASK-TNLSLCENNMIVL 159  fission yeast
399300    160 KLLSEEVFDFSAEQMTQAKALHLKNSMSKEFEQIFKLCFQVLEQGS----SSSLIVATLESLLRYLHWIPYRYIYETNIL 235  baker's yeast
19074824  192 KRLNEEVFIFSEDSITTVRKRLLRNQLKIEFPQIFGFIKTILEYSRntemDESLLEATLESFQCFCESMPLDFIFLTEII 271  Encephalitozoon c...
19114840  160 RLLSEEIFDYSAEQMTQLKTKNLKNQMCGEFAEIFQLCSQILERAQ----KPSLIKATLGTLLRFLNWIPLGYIFETNIV 235  fission yeast
399300    236 ELLSTKFMTSPDTRAITLKCLTEVSNLK--------IPQDNDLIKRQTVLFFQNTLQQIATSVMPVTADLKATYANANGN 307  baker's yeast
19074824  272 DLVLEHLNSMHS--VACLSCLIEIVDLGrnrnlartHEIEGAEKERILSIHGQCIEFLKMYFNKFQEERIYEVYGGMDKA 349  Encephalitozoon c...
19114840  236 ELITNRFLNVPDFRNVTIECLTEIASLTs-------QPQYN----DKFVTMFNLVMTSVN-SMLPLQTDFREAYEESSTN 303  fission yeast
399300    308 DQSFLQDLAMFLTTYLARNRALLESDESLrELLLNAHQYLIQLSKIEERELFKTTLDYWHNLVADLFYEVQRLPATEMSP 387  baker's yeast
19074824  350 EKIFVLKLAQLLSSLYEVYISLLEARDMA--NTKIGLGYLIQISRINNSNIFSTAFEMWNKFVFDLYSEF---------P 418  Encephalitozoon c...
19114840  304 EQDFIQNLALFLCAFFSSHLRPLENPENQ-EVLLNAHSYLLNISRINEREIFKICLEYWSKLVAQLYEEMQQIPMSEMNP 382  fission yeast
399300    388 LIQLSVGSQAISTgsgalNPEYMKRFPLKKHIYEEICSQLRLVIIENMVRPEEVLVVENDEGEIVREFVKESDTIQLYKS 467  baker's yeast
19074824  419 ------------------FTNQDSTKRLRRSNYIGVLNQLMGTLVDKMPRPEEVFIVVDEYNEVIRKKMTDTDQIEFYRK 480  Encephalitozoon c...
19114840  383 LLNLSSPTSLISS-----NPNMLANLPLRKHIYKDILSTLRLVMIENMVKPEEVLIVENDEGEIVREFVKETDTITLYKS 457  fission yeast
399300    468 EREVLVYLTHLNVIDTEEIMISKLARQIDGSEWSWHNINTLSWAIGSISGTMSEDTEKRFVVTVIKDLLDLTVKKRGKDN 547  baker's yeast
19074824  481 MRGCLYHLAFLIEDDMKKYFIGKVGLQLDDKEWDCNYLNRLCWAIGSISGAFSEVNEREFFVNILKHLLALCEMKSFKTD 560  Encephalitozoon c...
19114840  458 MREVLVYLTHLDVVDTEIVMTEKLARIVVGTEWSWQNLNTLCWAIGSISGAMNEEMEKRFLVNVIKDLLGLCEMKRGKDN 537  fission yeast
399300    548 KAVVASDIMYVVGQYPRFLKAHWNFLRTVILKLFEFMHETHEGVQDMACDTFIKIVQKCKYHFVIQQPRESEPFIQTIIR 627  baker's yeast
19074824  561 KAVIASNIMFIIGQYHRFLLHNKSFLKTVVKKLFEFMDEDHEGIKDMACDNFFKIVEKCPVEFLTQREGD-EIFIVYILK 639  Encephalitozoon c...
19114840  538 KAVVASNIMYVVGQYPRFLKAHWKFLKTVVNKLFEFMHEYHEGVQDMACDTFIKIAQKCRRHFVAQQLGETEPFINEIIR 617  fission yeast
399300    628 DIQKTTADLQPQQVHTFYKACGIIISEERSVAERNRLLSDLMQLPNMAWDTIVEQSTANPTLLLDSETVKIIANIIKTNV 707  baker's yeast
19074824  640 NLPAITGTLEFYQKRIVYEALLMVIREVPKTRDYKSRVLSYADLLLSSLLNFNILADEHINRLS-TMISNVDEAKMISHV 718  Encephalitozoon c...
19114840  618 NLAKTTEDLTPQQTHTFYEACGYMISAQPQKHLQERLIFDLMALPNQAWENIVAQAAQNAQVLGDPQTVKILANVLKTNV 697  fission yeast
399300    708 AVCTSMGADFYPQLGHIYYNMLQLYRAVSSMISAQVAAEGLIATKTPKVRGLRTIKKEILKLVETYISKARNLDDVVKVL 787  baker's yeast
19074824  719 LKSHALTYRLLPETCSSSCIQIFPKFFTIFDICNSITLE---NKEGTAFNNAKAVKAEIIELFATVI----DSKFVQNDF 791  Encephalitozoon c...
19114840  698 AACTSIGSGFYPQIAKNYVDMLGLYKAVSGLISEVVAAQGNIATKTPHVRGLRTIKKEILKLVDAYISRAEDLELVGNTL 777  fission yeast
399300    788 VEPLLNAVLEDYMNNVPDARDAEVLNCMTTVVEKVG---HMIPQGVILILQSVFECTLDMINKDFTEYPEHRVEFYKLLK 864  baker's yeast
19074824  792 VNMVCEKVIFDYKNN-PVYKEPAILSLGSSIVRNVEndgSVIYLQREAFMISALIEPSIPFVMQADENLEISKNYLLLME 870  Encephalitozoon c...
19114840  778 IPALFEAVLLDYLQNVPDARDAEVLNLITTIVNQLS---ELLTDKIPLVLDAVFGCTLEMISKDFSEYPEHRAAFFQLLR 854  fission yeast
399300    865 VINEKSFAAFLE--LPPAAFKLFVDAICWAFKHNNRDVEVNGLQIALDLVKNIERMGnVPFANEFHKNYFFIFVSETFFV 942  baker's yeast
19074824  871 NMLLFSFSSFFSslFGQPSFRQVYNTLLYSLICI-RDVSDLSLNCLTIIFKKCHEQK----IYQFYAQNYMSTLENILGI 945  Encephalitozoon c...
19114840  855 AINLNCFPALLN--IPAPQFKLVINSIVWSFKHVSRDIQETGLNILLELINNMASMG-PDVSNAFFQTYYISLLQDILYV 931  fission yeast
399300    943 LTDSDHKSGFSKQALLLMKLISLVYDNKISVPLYQEaevpqGTSNQVYLSQYLANMLSNAFPHLTSEQIASFLSALTKQY 1022 baker's yeast
19074824  946 IFDKDMKYNFDQQCLLFAFMIRISKD----VPSLDG-----INPNITILSEYIVGLFVKSFPNITQESVKIFSVGLFELC 1016 Encephalitozoon c...
19114840  932 LTDSDHKSGFKLQSLILARLFYLVESNQITVPLYD--------------------------------------------- 966  fission yeast
399300   1023 KDLVVFKGTLRDFLVQIKEVGGDPTdylfAEDKENALMEQNRleREKA 1070 baker's yeast
19074824 1017 GDDEIFKEHVEDFRVKVYEFGTDED----LQEEIDLKNERIR--RCKN 1058 Encephalitozoon cuniculi
19114840      ------------------------------------------------      fission yeast
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