Conserved Protein Domain Family
COG5
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pfam10392: COG5 
Golgi transport complex subunit 5
The COG complex, the peripheral membrane oligomeric protein complex involved in intra-Golgi protein trafficking, consists of eight subunits arranged in two lobes bridged by Cog1. Cog5 is in the smaller, B lobe, bound in with Cog6-8, and is itself bound to Cog1 as well as, strongly, to Cog7.
Links
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Statistics
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PSSM-Id: 192566
Aligned: 16 rows
Threshold Bit Score: 95.8343
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q6CLE2     11 EDFLEADFQPLRFANDLLKv------------TNNGTDTDVLDLKTCVKRCSYDLQELDRRIEGAIKTNPSHVLEQIEKR 78  Kluyveromyces lactis
Q6BT79     15 EAFLETSFQPLQFANDLLL-------------ATNDKNGSELDGLTPLKKLKFDIDECDKRMASIASTNYESLMSNFSQI 81  Debaryomyces hansenii
XP_723418  17 EAFLETNFDPQQFANELLL-------------ATNGQENPHLDLVTPIKKLKFDIQECDKRIEKISSSNYSSLISNFQKI 83 
P53951     14 ESLLEPDFDAKQFGNDLLK-------------ATNNNDTTILDLNTPLKKLNYDLHEIDSRIDQLMNSNPLEIIELIYKN 80  Saccharomyces cere...
Q6FTM6      9 EELIDPEFDSKSYSNSMLK--------------AMNTTSNELDIDAPKKKAQYDADELKSRYESFLKSHASGLMDEFDRE 74  [Candida] glabrata
O42962      8 SDYKKSDFDPKAQAERVLI-------------SVHADSDVNEDKEVARKRLGYALKEVERQITDLIVHEETTLTKNVSSS 74  Schizosaccharomyce...
Q5KKM0     10 KPFLSDSFDVHSYTNAILQgrqytpdqsqqnnNKEDNDKADLDVGAELARLNYGIEDVTKQLRQEITASHLLLLNHLTTS 89  Cryptococcus neofo...
Q54HE0     63 NQFLGEDFNVVHYTSNALK---------------------VSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNI 121 Dictyostelium disc...
Q9UP83     66 SDFLNEDFDVKTYTSQSIH---------------------QAVIAEQLAKLAQGISQLDRELHLQVVARHEDLLAQATGI 124 human
Q9C9V9     57 SPFLSSSFSSASFSSAALA---------------------SGSPASTAERLHQAIRLLDSQLRNDVISRHPELLAQLSSL 115 thale cress

Q6CLE2     79 KKEKSfVGDTLKSNTEYLSMSYNRLQQDILEPFERALKLQTVSSKIHQTTTLLRSSLIYVHMISQL 144 Kluyveromyces lactis
Q6BT79     82 EKTRSlVNEQINPLVERVNNSFERIKSGVIQPYEEALKKNNALKRIHLTLNLLRGAGYFMFLVQQL 147 Debaryomyces hansenii
XP_723418  84 AEYQKiLTTQINPNLERINAPFKRIKQEVVEPFDEAMKLNKALKRIHLTLELLRGTSFFIFIIQQI 149
P53951     81 EHVNStIVGELKPSLGYMNMSYDRLKNQVLDPYERARKVQLALSKVYQTSFLLRGALLYIHLSNKL 146 Saccharomyces cerevisiae S288C
Q6FTM6     75 RKLNGsISAELKPSLEYMSISYNRLLEQVLVPYERAQKLQAALNSVHQTSTLLRDVLMFVHLSQQI 140 [Candida] glabrata
O42962     75 LNAQS-YLQDIEGKLEQLMLVYERIRSLVVIPSENLGPLHEAIVNLHSTYMTLYWLGEFFGIQAKL 139 Schizosaccharomyces pombe 972h-
Q5KKM0     90 LSLSS-HLSPIRSSLISLSASIDRLHSKIHTPYTNLSTLVRRQQNLRQIKDIARRASRFVIVARRL 154 Cryptococcus neoformans
Q54HE0    122 KELDQ-LTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKL 186 Dictyostelium discoideum
Q9UP83    125 ESLEG-VLQMMQTRIGALQGAVDRIKAKIVEPYNKIVARTAQLARLQVACDLLRRIIRILNLSKRL 189 human
Q9C9V9    116 SHADV-SLSSLRSSVSSLQSSIRRVRSDLSEPIKSIRSKSVQLSNLHTATELLSHSVRTLRLSKKL 180 thale cress
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