Conserved Protein Domain Family
SRP40_C

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pfam05022: SRP40_C 
SRP40, C-terminal domain
This presumed domain is found at the C-terminus of the S. cerevisiae SRP40 protein and its homologs. SRP40/nopp40 is a chaperone involved in nucleocytoplasmic transport. SRP40 is also a suppressor of mutant AC40 subunit of RNA polymerase I and III.
Statistics
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PSSM-Id: 461525
Aligned: 85 rows
Threshold Bit Score: 56.3877
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:THAPS_23336    531 PFKRVDDQYWGDvaTKdggAMADNSYEgafG----SDGFGVKASEKLLTVRGKDFCREKNKRKRtfngfSKSAGGAITMn 606 
XP_001237649      1119 RFRRIKPEEIEI--DE---RLMDNSYE---AkrnaEGAYGERANRILKFTKGKSFRHEKTKKKR-----SGYLGGLIDK- 1184
XP_011493704       538 RFRRIKEEHISI--DD---RLRDNSFD---AkknaRGSFGERANEILKHTRGKSFRHEKTKKKR-----SGYRGGFIDM- 603 
XP_002434447       491 PFRRVKPEAVNI--DP---KLRDNSFE---AkagaRGSWGEKANQVLRTVKGKDFRHEKTKKKR-----GTYSGGAIDM- 556 
XP_008216212       543 PFRRVNDEEVEL--DP---KLANNSFE---AkrgaRGSWGEKANLDLKHTRGKSFRHEKTKKKR-----GSYRGGQIDT- 608 
EKC37854           418 PFRRVKSDEVLI--NR---KLSNNSFE---AkkgaAGSWGEKAHRDLKHTQGKSFKREKGKKKK-----GQYRGGSIDT- 483 
XP_002115285       355 PFRRVNIEVSNI--ES---QFRDNSFE---AkknaKNSWGDKANKDLKFTKGKSFRHEKTKKKR-----GSYRGGSIDM- 420 
FlyBase:CG7421-PF  612 PFRRVRTEDVVV--DS---RVQDMSFE---AkknaAGSWGERANKDLKHTRGKSFKHEKTKKKR-----GSYRGGQIDV- 677 
XP_002424762       494 PFRRVQSEQVFI--DP---RLKDNSFE---AkknaRGSWGEKANYDFKHTRGRAFRHEKTKKKR-----GSYRGGHIDM- 559 
XP_009017197       420 PFKRVDPSKIIV--DE---RMQDNSFE---AkpgaKGSWGEKANEDLKTTKGKSFRHEKTKKKR-----GSYKGGAIDT- 485 
jgi:THAPS_23336    607 S-FSTKY 612 
XP_001237649      1185 SvNSIKF 1191
XP_011493704       604 GvNSIKF 610 
XP_002434447       557 SvNSIRF 563 
XP_008216212       609 SiNSIKF 615 
EKC37854           484 SvNSVKF 490 
XP_002115285       421 SvNSIKF 427 
FlyBase:CG7421-PF  678 GvNSIKF 684 
XP_002424762       560 SvNSIKF 566 
XP_009017197       486 GiNSIKF 492 
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