2XDV,4CCM


Conserved Protein Domain Family
JmjC_2
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pfam08007: JmjC_2 
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JmjC domain
This entry includes proteins with a JmjC domain that belong to the cupin superfamily, including Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66, Ribosomal oxygenase 1/2, and 50S ribosomal protein L16 3-hydroxylase from Escherichia coli. Proteins are bifunctional, acting as histone lysine demethylases and ribosomal histidine hydroxylases.
Links
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Statistics
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PSSM-Id: 462340
Aligned: 26 rows
Threshold Bit Score: 116.967
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2XDV_A   113 QFHQPQRFKDElWRIQEKLECYfgslvgsnvyITPAGsqGLPPHYDDVEVFILQLEGEKHWRLYH-----PTVPLAREYS 187 human
Q741E6   113 SLSHAIEVELNfptr-------------vnayVTPPHstGFVPHYDPHDVLVLQIEGCKTWRVSDe----PPVPPQQIQS 175 Mycobacterium avium...
Q7T3G6   154 QFHQPQRFQDElWRIQERLECFfgclvgsnvyITPAGaqGLPPHYDDVEVLILQLEGQKHWRLYE-----PTVPLAREYS 228 zebrafish
Q6DDJ7   133 QFHQPQRFNDAlWHIMEKLECFfgalvgsnvyITPQDsqGLPAHYDDVEVFILQLEGEKRWRLYN-----PVVPLARDYS 207 African clawed frog
O01658   399 QLVNPQTYDDRiWYLCEVIQEQfgcfvgantyLTPAGssGFAPHWDEIDAFLLQVEGRKYWRVWAp---eSAEEELPLES 475 Caenorhabditis elegans
Q8CD15   136 QFHQPQRYKDElWRIQEKLECYfgslvgsnvyMTPAGsqGLPPHYDDVEVFILQLEGTKHWRLYS-----PTVPLAHEYS 210 house mouse
4CCM_B   116 RLLCPQAFSTTvWQFLAVLQEQfgsmagsnvyLTPPNsqGFAPHYDDIEAFVLQLEGRKLWRVYRp---rVPTEELALTS 192 human
Q849M1   106 ELHPPI------ARLCEAIERElhtrvqanlyASWSAteGFGVHWDDHDTVIVQLDGAKRWRIYGttrpfPLYRDIADPG 179 Streptomyces violac...
Q7N884    96 lVANGIINETKiDQLAKACSSFtdshpfsslyLSYGEksSFKPHWDSRDIFAIQLSGKKRWIIYKpsfpdPVYLHQSKDM 175 Photorhabdus laumon...
AAG55932  98 ALMRPFRELPD-WRIDDLMISF----------SVPGG--GVGPHLDQYDVFIIQGTGRRRWRVG------EKLQMKQHCP 158

2XDV_A   188 VEAEERIG----RPVHEFMLKPGDLLYFPRGTIHQADTPA---GLAHSTH-VTISTYQN 238 human
Q741E6   176 RKGVGADGpaswT---DVCLRPGDVLYLPRGQVHSARTHSe-pSVHLTVG-LHAPTVLT 229 Mycobacterium avium subsp. paratuberculosis
Q7T3G6   229 LEPEGRIG----APTHDFILQAGDLLYFPRGTIHQADTPA---GAGHSTH-LTLSTYQN 279 zebrafish
Q6DDJ7   208 VVPEDQIG----SPTHDFVLKPGDLLYFPRGVIHQAQALp---GSSHSTH-VTISTYQN 258 African clawed frog
O01658   476 SDNFTEDDmkgrEPVFEGWIEKGDMIYIPRGYIHQARTDSkvhSLHVTVStGRQWSFAN 534 Caenorhabditis elegans
Q8CD15   211 VESEDRIG----TPTHDFLLKPGDLLYFPRGTIHQAETPS---GLAYSIH-LTISTYQN 261 house mouse
4CCM_B   193 SPNFSQDDl--gEPVLQTVLEPGDLLYFPRGFIHQAECQDgvhSLHLTLStYQRNTWGD 249 human
Q849M1   180 EAPT--------EPVADLVLWPGDVLYVPRGVWHAVSADQgvrSLHVTCG-LQTHTATD 229 Streptomyces violaceoruber
Q7N884   176 ENTYPCPS----EPYDDFVLETGDVLYLPRGWWHNPLPLGe-eTIHLSVG-IFPPYAHE 228 Photorhabdus laumondii subsp. laumondii
AAG55932 159 HPDLLQVDp--fEAIIDEELEPGDILYIPPGFPHEGYALEn--AMNYSVG-FRAPNTRE 212
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