Conserved Protein Domain Family
PLN02906

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PLN02906: PLN02906 
xanthine dehydrogenase
Statistics
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PSSM-Id: 215491
Aligned: 16 rows
Threshold Bit Score: 2164.06
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
219127857    1 NQTLLSFLRDvLRLTGSKLGCAEGGCGACTVMLSKKNVDTGKIKHFSVNACLMPVLAADGCHVTTVEGIGTvKNDNLHPV 80  
115453639   39 HLTLLQYLRD-IGLPGTKLGCGEGGCGACTVMVSCYDQTTKKTQHFAINACLAPLYSVEGMHIITVEGIGN-RQRGLHPI 116 
168016458   41 HQTLLEYLRG-IGLTGTKLGCGEGGCGACTVMLSHYDTSTGSIVNRAINACLAPIYSVEGMHVITVEGIGN-RRLGLHPV 118 
225435470   37 HLTLLEYLRD-IGLTGTKLGCGEGGCGACTVMVSYFDENSKKCVHYAVNACLAPLYSVEGMHVITVEGIGN-RRNGLHPI 114 
225435472   26 HLTLLEYLRD-IGLTGTKLGCGEGGCGACTVMVSYFDENSKKCVHYAVNACLAPLYSVEGMHVITVEGIGN-RRNGLHPI 103 
224106165   38 HLTLLEYLRD-IGLTGTKLGCGEGGCGACTVMVSHYNKVLKKCVHYAVNACLAPLYSVEGMHIITVEGVGN-RKIGLHPI 115 
255080464   25 EQTLLAYLRG-LGLSGTKLGCGEGGCGACTVMVSNYDRAKGEVQHRAVNACLTPLYACEGTHVITVEGLGT-KRGGLHPV 102 
255544848   34 HLTLIEYLRD-IGLTGTKLGCGEGGCGACTVMVSYYDRKLNKCVHYAINACLAPLYSVEGMHVITVEGVGN-RKSGLHPI 111 
302765308   34 HMTLLEYLRG-LGLTGTKLGCGEGGCGACTVMLSFFDNGEDKINHRAINACLAPLYSVEGMHVMTVEGIGS-RRKGLHKV 111 
302776502   34 HTTLLEYLRG-LGLTGTKLGCGEGGCGACTVMISFFDNEEDKINHRAINACLAPLYSVEGMHVMTVEGIGS-RRKGLHKV 111 
219127857   81 QNAMVDMHGSQCGFCTPGIIVSIYALLAN---NPTTAYLEEHLDGNLCRCTGYRPIWDAARSLCDDGEELVK-------G 150 
115453639  117 QERLAMAHGSQCGFCTPGFVMSMYALLRSseqPPTEEQIEDSLAGNLCRCTGYRPIIDAFRVFSKRDDLLY--------N 188 
168016458  119 QEALASAHGSQCGFCTPGFVMSMYSLLRTkkdKPTQAEIEECLAGNLCRCTGYRPILDAFRVFAKSETSLYTneaiaaaG 198 
225435470  115 QESLALSHGSQCGFCTPGFIMSMYALLRSsqtPPSEEQIEESLAGNLCRCTGYRPIIDAFRVFAKTDDVLYT-------D 187 
225435472  104 QESLALSHGSQCGFCTPGFIMSMYALLRSsqtPPSEEQIEESLAGNLCRCTGYRPIIDAFRVFAKTDDVLYT-------D 176 
224106165  116 QESLARSHGSQCGFCTPGFIMSMYALLRSsevPPTEEQIEECLAGNLCRCTGYRPIIDAFQVFAKTDDAFYT-------N 188 
255080464  103 QTALAHAHGSQCGFCTPGFVMSMYALLRSkktKPTELEIEEALGGNLCRCTGYRPILEGFRTFARNAPDSAY-------S 175 
255544848  112 QESLARGHGSQCGFCTPGFIMSMYALLRSsqePPTAEQIEECLAGNLCRCTGYRPIVDAFQVFAKSNDALYT-------D 184 
302765308  112 QEVLANTHGSQCGFCTPGFVMSMYALLRTckmPPTEEQIEESLAGNLCRCTGYRPILEAFRSFTKADSFLYWddsakasG 191 
302776502  112 QEVLANTHGSQCGFCTPGFVMSMYALLRTcktPPTEEQIEESLAGNLCRCTGYRPILEAFRTFTKADSFLYWddsakasG 191 
219127857  151 PCGTACRECpeREACDQD---CNVQDKATSADNMCCSsskdkMSTYKETFLTNKDSWRAQPNVMFPKVLMDTASVESTLL 227 
115453639  189 NSSLKNADG--RPICPSTgkpCSCGDQKDINGSESSLlt-ptKSYSPCSYNEIDGNAYSEKELIFPPELQLRKVTSLKLN 265 
168016458  199 GVPTNKSTGs-EFVCPSTgkpCDCGKTPSKVP---------------------------RAEPIFPSKLKERKPQPLVLR 250 
225435470  188 RSSLSLQEG--EFICPSTgkpCSCKSGSSNDKDAAKSnmscvDRYEPISYSEIQGSTYTEKELIFPPELLLRKLTPLNMN 265 
225435472  177 RSSLSLQEG--EFICPSTgkpCSCKSGSSNDKDAAKSnmscvDRYEPISYSEIQGSTYTEKELIFPPELLLRKLTPLNMN 254 
224106165  189 TSSSSLQSG--EFLCPSTgkpCSCKSKSLSGAGTCKQstangNKYEPVSYSEVDGSTYTDKELIFPPELLLRKLTALNLN 266 
255080464  176 GETINGSDS--TPICPSTgqpCTNGCGDTPAA--------------KALGAAEDDPVTAVREPIFPPELKRRVPTPLALP 239 
255544848  185 HSALSLEEG--ESVCPSTgkpCSCKSKTVIDPGNCKRsaacgDSCKPISYSEVNGSTYTDKELIFPPELLLRKLTPLSLS 262 
302765308  192 VAVNRASQG--GKICPGTgrpCDCGSEKKTGC---------------CSVQEKPSEIKDRGELIFPPELMTRKVQSLVLK 254 
302776502  192 VAVNRASQG--GKICPGTgrpCDCGPE---------------KKTGCCSVQEKPSEIKDRGELIFPPELMTRKVQSLVLK 254 
219127857  228 TkplmivdrseyHTGGTWFKPTTFAGLLALLQEFGgtgtgACKIVVGNTEVGIETRFKYAVYPRLISPSEsIRELFGFEV 307 
115453639  266 G-----------FNGIRWYRPLKLKQVLHLKACYP-----NAKLIIGNSEVGVETKFKNAQYKVLISVTH-VPELHTLKV 328 
168016458  251 G-----------RLGLKWYRPTSLSHLLALKKEYP-----SAKMVGGNTEVGIEVRFKNLQYPVLIATTH-VPELSTIKV 313 
225435470  266 G-----------FGGLKWYRPLGLKHLLELKARYP-----DAKLVVGNSEVGIEMRLKRIQHQVLISVIN-IPELTMLSV 328 
225435472  255 G-----------FGGLKWYRPLGLKHLLELKARYP-----DAKLVVGNSEVGIEMRLKRIQHQVLISVIN-IPELTMLSV 317 
224106165  267 G-----------FGGLKWFRPLKIQHLLELKAKYP-----DAKLVMGNTEVGIEMRLKRIQYKVLISVAH-VPELNVLNV 329 
255080464  240 Gai------------atWHRPTTLAGLLALKKAHP-----DARLVCGNTEVGVEVKFKNMKYPVIVAPTH-VPELTEVTI 301 
255544848  263 G-----------FGGLKWYRPLRVQHLLELKAKYP-----AAKLLIGNTEVGIEMRLKRIQYQVLISVAH-VPELNVLTV 325 
302765308  255 G-----------AEDLQWFRPLSLPDLLDLKKRYP-----DAKLVVGNSEVGIETRFKNLRYPVLIAATH-VAELNAIKV 317 
302776502  255 G-----------AGDLQWFRPLSLPDLLDLKKRYP-----DAKLVVGNSEVGIETRFKNLRYPVLIAATH-VAELNAIKV 317 
219127857  308 SGANLIIGSCCPLSTIQHHCNALGE--QDLLVRTVMPIHDMLRWFASTQIRNVACLGGNLVTASPISDMNPMLASMGAKL 385 
115453639  329 KEDGIHIGSSVRLAQLQNFLRKVILerDSHEISSCEAILRQLKWFAGTQIRNVASVGGNICTASPISDLNPLWMATGATF 408 
168016458  314 IDSGVEIGSSVTLTNIFETFSEIVKtrNEDETSGCKAIIEQLRWFAGAQIRNVSSIGGNIVTASPISDLNPLWIATGTIF 393 
225435470  329 KDDGLEIGAAVRLSSLQNLLRKVLAdrVAYETSACKAFIEQIKWFAGTQIKNVASVGGNICTASPISDLNPLWMAAGAKF 408 
225435472  318 KDDGLEIGAAVRLSSLQNLLRKVLAdrVAYETSACKAFIEQIKWFAGTQIKNVASVGGNICTASPISDLNPLWMAAGAKF 397 
224106165  330 KDDGLEIGAAVRLMELLQMFRKVVNerAAHETSSCKAFIEQIKWFAGTQIKNVACVGGNICTASPISDLNPLWMAAGAKF 409 
255080464  302 AEDSLVLGASVTLTTLLNTCETLTLtlGPVRTSGLVAIKEQLRWFAGPQVRNVSSVGGNVCTASPISDLNPLWIACGATF 381 
255544848  326 KDDGLEIGAAVRLTELLKMLRKVVNerATHEMSSCKALIEQLKWFAGTQIKNVASVGGNICTASPISDLNPLWMAARAKF 405 
302765308  318 LDDGLNIGASVTLEKLREVMHACVKdrKAYEVSGCDAFLAQLKWFAGVQIRNVSSIGGNICTASPISDLNPLWIAAGAVF 397 
302776502  318 LDDGLNIGASVTLEKLREVMHACVKdrKAYEVSGCDAFLAQLKWFAGVQIRNVSSIGGNICTASPISDLNPLWIAAGAVF 397 
219127857  386 VIASLDAtDKtticrRYVDVSDFFVKYRTVDLKPTEILERIEVPVLRnPFEYLKPFKQARRREDDISIVTSGMRLKLTVV 465 
115453639  409 EIIDVNN-NI-----RTIPAKDFFLGYRKVDLKPDEILLSVILPWTR-PFEFVKEFKQAHRREDDIALVNAGMRVYIRKV 481 
168016458  394 TVAGYGA-SP-----RQVPAKDFFLGYRKVDLKENEILISVFMPFTR-PFEYVKEFKQAHRRDDDIALVNAGIRVSLAES 466 
225435470  409 RVINCKG-NI-----RTVLAENFFLGYRKVDLAHDEILLSIFLPWTR-PFEFVKEFKQAHRRDDDIAIVNAGMRVYLQEK 481 
225435472  398 RVINCKG-NI-----RTVLAENFFLGYRKVDLAHDEILLSIFLPWTR-PFEFVKEFKQAHRRDDDIAIVNAGMRVYLQEK 470 
224106165  410 QIIDCKG-NI-----RTIMAENFFLGYRKVDLASGEILLSIFLPWTR-PLEHVKEFKQAHRRDDDIAIVNAGMRVFLEEK 482 
255080464  382 EIESLDR-GA-----RRVAARDFFKGYRSTDLKPDEVLTAVALPLTE-KGEYVREFKQSHRREDDIAIVTAGMRAKFDVV 454 
255544848  406 QIIDCKG-NR-----RTTLAENFFLGYRKVDLASDEVLLSIFLPWTR-PFEHVKEFKQAHRRDDDIAIVNAGMRVFLEEK 478 
302765308  398 TLVDDSG-LP-----RSVQASDFFIGYRRVALRKGEILASVFLPWTR-KNEYIKEFKQSHRRDDDIALVNAGMRVHLKEE 470 
302776502  398 TLVDDSG-LP-----RSVQASDFFIGYRRVALRKGEILASVFLPWTR-KNEYIKEFKQSHRRDDDIALVNAGMRVHLKEE 470 
219127857  466 DHEYIIEEASLAFGGMAPTTVLATETVKILIGSAFCAKSFESATEALLQELSLPEAVPGGQAAFRMTLATSFLYKFFLSV 545 
115453639  482 EGDWIISDVSIIYGGVAAVSHRASKTETFLTGKKWDYGLLDKTFDLLKEDVVLAENAPGGMVEFRSSLTLSFFFKFFLHV 561 
168016458  467 DGAWIVQDSCLAYGGVAAMVAVAKRTQEFLRGKPWSRETLDQALGLLEQEIHMADNAPGGMVQFRRSLISSFFFKFFLFT 546 
225435470  482 EEKWVVSDASIAYGGVAPLSLSASKTKDFLIGKIWNRELLQDALKILQKNILIKDDAPGGMVEFRKSLTLSFFFKFFLWV 561 
225435472  471 EEKWVVSDASIAYGGVAPLSLSASKTKDFLIGKIWNRELLQDALKILQKNILIKDDAPGGMVEFRKSLTLSFFFKFFLWV 550 
224106165  483 GEDLVVSDALIVYGGVAPLSLSAVKTKEFIIGKKWDQELLQGALKFLEIDIFLKEDAPGGMVEFRKSLTLSFFFKFFLWV 562 
255080464  455 DNVPTVAEIAFGFGGMSFKTVSCPKTSAALAGKPWTDETLKLALATLPKDLPMSPDVPGGMCEFRRSLANSFMFKFYVDC 534 
255544848  479 GDHWVVSDASIVYGGVAPLTLSAAKTKKFLIGKNWNQELLEGVLKVLETDILLKEDAPGGMVEFRKSLILSFFFKFFLWV 558 
302765308  471 TGKWLVSGISLVYGGVAAVPVRASKTETFMQGKVWDKSTLEGALSELQKDIIIADNAPGGMAEFRRSLILSFFFKYFLMV 550 
302776502  471 TGKWLVSGISLVYGGVAAVPVRASKTETFMQGKVWDKSTLEGALSELQKDIIIADNAPGGMAEFRRSLILSFFFKYFLMV 550 
219127857  546 VADLKADISAIRA------NPSAYPGMEVDLPDPPSVDTM--EESGTTTVVGKASAHQSGPLHCTGEAAYCDDIPMPAGT 617 
115453639  562 THEMNIKGFWKDG------LHATNLSAIQSFTRPVGVGTQcyELVRQGTAVGQPVVHTSAMLQVTGEAEYTDDTPTPPNT 635 
168016458  547 NYKLEAHANFSHG------LPESYRSAVTPYEREPSHGIQvfQTLPNGTAVGLPFQHQSANLQVTGEAEYVDDIAMPPNG 620 
225435470  562 SHQMDGQRFFLET------VPISHLSAVQPFHRPSVTGMQdyEVVKHGTAVGSPEIHLSSKLQVTGEAEYADDMPMPPNG 635 
225435472  551 SHQMDGQRFFLET------VPISHLSAVQPFHRPSVTGMQdyEVVKHGTAVGSPEIHLSSKLQVTGEAEYADDMPMPPNG 624 
224106165  563 SQQISVKKSTG--------IPLSYLSAAQPFQRPSIMGSQdyEIRKHGTSVGSPEIHLSSRLQVTGEAEYADDAPMPSNG 634 
255080464  535 CRRLEADGLVTDAvysaagLDEADLSAADRFHRPFPRGAQy-TQVRDGSTVGQPTMHQSAEVQVTGEAEYADDIAKPAGM 613 
255544848  559 SHQMDGKKSIRAT------IPSSHLSAVQPFHRPSVVGCQdyEIRKHGTAVGSPEVHLSSRLQVTGEAEYVDDTLMSSNG 632 
302765308  551 ADKLQQDENVEHE------FSERFMSAADPYKRDISSGMQnfKTIVDGSAVGQSIAHVSAELQVSGEAQYLDDEPLPPNG 624 
302776502  551 ADKLQQDENVQHE------FSERFMSAADPYKRDISSGMQnfKTIVDGSAVGQSIAHVSAELQVSGEAQYLDDEPLPPNG 624 
219127857  618 LQACLVLARECGGVFEAMDVAEALAIPGVIGIYNYDSLvglGGSNELGPIIHDETVFlrPGDIVRTVGQVLGIAVAETLE 697 
115453639  636 LHAALVLSTKAHARILSIDASLAKSSPGFAGLFLSKDV---PGANHTGPVIHDEEVF--ASDVVTCVGQIVGLVVADTRD 710 
168016458  621 LHAALVLSTRPHARIVSIDASEAENQAGFEGFFSAKDL---PGANDIGAIVHDEELF--ATTTVTCVGQVIGIVVADTHE 695 
225435470  636 LHAALVLSRKPHARILSIDDSGAKSSPGFAGIFFHKDV---PGGNAIGPVVNDEEIF--ASEFVTFVGQVIGVVVADTQE 710 
225435472  625 LHAALVLSRKPHARILSIDDSGAKSSPGFAGIFFHKDV---PGGNAIGPVVNDEEIF--ASEFVTFVGQVIGVVVADTQE 699 
224106165  635 LHAALVLSRKPHAKILSIDDSEAKSLPGVAGIFLAKDV---PGDNHIGAIIHDEELF--ATKYVTCVGQVIGVVVADTHE 709 
255080464  614 LHAALVLSTVPHGKILDIDPAAALATPGVHGFFSAKDV----PNNVIGPAVLDEEVF--ASEYVTCVGHPVGIVVADTQD 687 
255544848  633 LHAALVLSKKPHARIVSIDDSEAKSSPGFAGIFFAKDI---PGDNHIGAIIADEELF--ASEFVTCVGQVIGVVVADTHE 707 
302765308  625 LHGALVLSTRPHARIVSVSYREAETVPGFAGYFCAKDV---PGGNDIGAVAHDEELF--ATNVVTCVGQVIGVVVADTQY 699 
302776502  625 LHGALVLSTRPHARIVSVSYREAETVPGFAGYFCAKDV---PGGNDIGAVAHDEELF--ATNVVTCVGQVIGVVVADTQY 699 
219127857  698 AAEFAARTVHVTCsqPKEKVVVTVEDAIETGSFYE---FSRHSMERGDIaiidslaTIADSTGTPSLgdvvKISGTFRSG 774 
115453639  711 NAKAAANKVNIEY--SELPAILSIEEAVKAGSFHP---NSKRCLVKGNV-------EQCFLSGACDR----IIEGKVQVG 774 
168016458  696 NAKDAARKIKIVY--EDLPTLLDLDAAVAAQKFHP---GSERVLEMGNV-------DAFFENARGSDdv-lAVEGEVRMG 762 
225435470  711 NAKLAARKVHVKY--EELPAILSIEDALKAKSFLP---NTERHIEKGDV-------DLCFQSGCCDK----ILEGEVHVG 774 
225435472  700 NAKLAARKVHVKY--EELPAILSIEDALKAKSFLP---NTERHIEKGDV-------DLCFQSGCCDK----ILEGEVHVG 763 
224106165  710 NAKLAAAKVVVEY--EELPAILSIQEAVDAKSFHP---NSEKCLKKGDV-------DVCFQSGQCDK----IIHGEVHVG 773 
255080464  688 IALEASRLVRVKY--EELPAILNIDEAIAADSYHTwpgFTDHGIEDGDV-------DAAMAECEAAGr---VVEGDARCG 755 
255544848  708 NAKMAATKVYVEY--EELPAILSIQEAVDAESFHP---NSEKCLKKGDV-------ELCFHSGQCDR----IIEGEVQVG 771 
302765308  700 AARAAALKVKVVY--EDLPAILSIEDAIEAESFLL---KAPRVLSKGNV-------QECFASGKCDH----IVEGTVQMG 763 
302776502  700 AARAAALKVKVVY--EDLPAILSIEDAIEAESFLL---KAPRVLSKGNV-------QECFASGKCDH----IVEGTVQMG 763 
219127857  775 AQEHFYLETNAALVIPSESDTNLTIYASTQAPTETQAYCASATGTPASKVVVRMKRMGGGFGGKETRSVFAACAAAVAAK 854 
115453639  775 GQEHFYMEPQSTLVWPVDSGNEIHMISSTQAPQKHQKYVANVLGLPQSRVVCKTKRIGGGFGGKETRSAIFAAAASVAAY 854 
168016458  763 GQEHFYLEPNSTLVWTTDAGNEVHLLSSTQAPQKHQRYVAHVLGIPQHKVVCKLKRIGGGFGGKETRSAFIAAAASVPAY 842 
225435470  775 GQEHFYLETNSSLVWTTDSGNEVHMISSTQCPQKHQKYVSHVLGLPMSKVVCKTKRIGGGFGGKETRSACFAAVACVPSY 854 
225435472  764 GQEHFYLETNSSLVWTTDSGNEVHMISSTQCPQKHQKYVSHVLGLPMSKVVCKTKRIGGGFGGKETRSACFAAVACVPSY 843 
224106165  774 GQEHFYLETQSSLVWTMDCGNEVHMISSTQAPQKHQQYVAQVLGLPMSKVVCKTKRIGGGFGGKETRSAFIAAAASVPSY 853 
255080464  756 GQEHFYLEPMVSLVWCGDN-DDLITISSTQAPQKHQKLISSALKIPCNRVVCKTKRLGGGFGGKETRAAFLNVCAAIPAF 834 
255544848  772 GQEHFYLEPQGSLVWTMDSGNEVHMISSTQAPQKHQKYVAHVLGLPMSKVVCRTKRIGGGFGGKETRSAFLAAVASIPSY 851 
302765308  764 GQEHFYLEPHGTTVWIQDGGNEVMMLSSTQAPQKHQYTVAHVLGIPMHRVVCKTKRIGGGFGGKETRGFVEAAAAAVPAY 843 
302776502  764 GQEHFYLEPHGTTVWIQDGGNEVMMLSSTQAPQKHQYTVAHVLGIPMHRVVCKTKRIGGGFGGKETRGFVEAAAAAVPAY 843 
219127857  855 CASRPIRLTLSRDVDMKITGTRHVFLSKYHASaqITENGaKLVAFDVKLFANGGSSFDLSGPVVDRALFHVDGVYMFPSF 934 
115453639  855 CLRQPVKLVLDRDIDMMTTGQRHSFLGKYKVG--FTDDG-KILALDLDVYNNGGHSHDLSLPVLERAMFHSDNVYDIPNV 931 
168016458  843 LLQRPVRITLDRDTDMAITGQRHAFMGKYKVV--FTKEG-KILALDVDIYNNGGNSLDLSGSVLERAMFHSDNVYSIKDM 919 
225435470  855 LLNRPVKLTLDRDIDMMISGQRHTFLGKYKVG--FTNDG-KVQALDLEIYNNGGNSLDLSGAVLERAMFHSDNVYDIPNV 931 
225435472  844 LLNRPVKLTLDRDIDMMISGQRHTFLGKYKVG--FTNDG-KVQALDLEIYNNGGNSLDLSGAVLERAMFHSDNVYDIPNV 920 
224106165  854 LLNRPVKLTLDRDVDMMITGQRHAFLGKYKVG--FTKEG-RLLALDLEIYNNAGNSLDLSLSVLERAMFHSDNVYEIPNI 930 
255080464  835 HMRKPISLVLDRHVDMAITGQRHAFLGKYKVG--YSPEG-KILALDMMLYNNAGNSLDLSAAIMDRAIFHSDGAYKIPNV 911 
255544848  852 LLNRPVKITLDRDADMMITGQRHSFLGKYKVG--FTNEG-KVLALDLKIYNNAGNSLDLSLAVLERAMFHSDNVYEIPNV 928 
302765308  844 LLRRPVKLVLDREVDMAITGQRHAFLARYKVG--FTNEG-KVMALDLQIYNNGGNSLDLSDAVLERSMFHSDNVYVIPNV 920 
302776502  844 LLRRPVKLVLDREVDMAITGQRHAFLARYKVG--FTNEG-KVMALDLQIYNNGGNSLDLSDAVLERSMFHSDNVYVIPNV 920 
219127857  935 RAEGVPCKTVQAPHTAFRGFGGPQGMAVVEHVMDHLALATNVDADKLRRMNMYNDGEATPFGMIVgghhsGNWNVPVMWD 1014
115453639  932 RVNGQVCFTNFPSNTAFRGFGGPQAMLIAENWIQHMATELKRSPEEIKELNFQSEGSVLHYGQLL-----QNCTIHSVWD 1006
168016458  920 RVRGRVCFTNQSSNTAFRGFGGPQGMLIVENWIERIASEVGRRPEEIRELNFQQDGDELHYGQIL-----EASRHRHAWA 994 
225435470  932 RINGKVCLTNFPSHTAFRGFGGPQGMLITENWIQRIATELKKSPEEIREINFQSEGCVTHYGQQL-----QHFTLPRVWN 1006
225435472  921 RINGKVCLTNFPSHTAFRGFGGPQGMLITENWIQRIATELKKSPEEIREINFQSEGCVTHYGQQL-----QHFTLPRVWN 995 
224106165  931 RVLGRVCFTNFPSHTAFRGFGGPQGMLIAENWIQKIAVELNKSPEEIREINFQGEGSILHYSQQL-----QHCTLGQLWN 1005
255080464  912 RVHGRCCKTNLPSNTAFRGFGGPQGVIFAEMWMDRVARKLGQPAEKIRHVNLYEEGETCHFGQVM-----ESSQLRACWD 986 
255544848  929 RILGKVCFTNFPSNTAFRGFGGPQGMIIAENWIQRIAVELNKSPEDIREINFQGDGSILHYGQQL-----QYCTLAQLWN 1003
302765308  921 RIFGNVCFTNIPSNTAFRGFGGPQGMLVTENWIEHIAKTLGVPASKIREINLQGEGYELHYSQVL-----ENCRIKQVWS 995 
302776502  921 HIFGNVCFTNIPSNTAFRGFGGPQGMLVTENWIEHIAKTLGVPASKIREINLQGEGYELHYSQVL-----ENCRIKQVWS 995 
219127857 1015 RLVQELDVPHRRERIAQFNAKHKWLKRGLCLIPTRFGIAFTTKFMNQGGALVHLYVDGTVLVTHGGTEMGQGLHTKVCQV 1094
115453639 1007 ELKVSCNFMEARKAVIDFNNNNRWRKRGIAMVPTKFGISFTTKFMNQAGALVQVYTDGTVLVTHGGVEMGQGLHTKVAQV 1086
168016458  995 ELKKSCEFEKRLAEVESFNAQHRWKKRGLAMVPTKFGISFTTKFLNQAGALVQVYTDGTVLVTHGGVEMGQGLHTKMAQI 1074
225435470 1007 ELKSSCEFLKARGEVDQFNLQNRWKKRGVAMVPTKFGISFTTKFMNQAGALVHVYTDGTVLVTHGGVEMGQGLHTKVAQV 1086
225435472  996 ELKSSCEFLKARGEVDQFNLQNRWKKRGVAMVPTKFGISFTTKFMNQAGALVHVYTDGTVLVTHGGVEMGQGLHTKVAQV 1075
224106165 1006 ELKLSSDLLRALEDVKQFNLQNRWKKRGVAMVPTKFGISFTTKFMNQAGALVHVYTDGTVLVTHGGVEMGQGLHTKVAQV 1085
255080464  987 EAVAKADVDSRRAAADAFNAANKHRKRGIAATPVKFGISFTALFMNQAGALVHCYLDGTVLVTHGGVEMGQGLHTKVAQI 1066
255544848 1004 ELKLSCNLLKAREEAIQFNLHNRWKKRGVAMVPTKFGISFTAKLMNQAGALVHVYTDGTVLVTHGGVEMGQGLHTKVAQV 1083
302765308  996 ELKSSCELASRMHEIDLFNKKNRWKKRGVAMVPTKFGISFTTKFINQAGALVQVYTDGTVLVTHGGVEMGQGLHTKIAQV 1075
302776502  996 ELKSSCELASRMHEIDLFNKKNRWKKRGVAMVPTKFGISFTTKFINQAGALVQVYTDGTVLVTHGGVEMGQGLHTKIAQV 1075
219127857 1095 AAQSFGIPLNDVYVNDTSTDKVANSLPTAASMSTDTYGMATLDACRQILKRLEPFREKLgADAP--LKDVAHAAFFARVD 1172
115453639 1087 AASSFNIPLSSIFISETSTDKVPNATPTAASASSDLYGAAVLDACQQIMARMEPVASRG-NHKS--FAELVLACYLERID 1163
168016458 1075 AASEFGIPLKDVFVSETATDKVPNSSPTAASASADMYGGAVLDACKQITARMSELSSKN-NYSS--FAELVTACYLERID 1151
225435470 1087 AASSFNIPLSSVFISETSTDKVPNSTPTAASASSDMYGAAVLDACEQIKARMEPIASKR-NFSS--FAELVTACYLERID 1163
225435472 1076 AASSFNIPLSSVFISETSTDKVPNSTPTAASASSDMYGAAVLDACEQIKARMEPIASKR-NFSS--FAELVTACYLERID 1152
224106165 1086 AASAFNIPLSSVFISETSTDKVPNTSPTAASASSDLYGAAVLDACEQIKARMEPVALKH-NFSS--FAELAGACYMQQID 1162
255080464 1067 CAAELGIETDSVYIAETSTDKVPNASPTAASASSDLYGAAVTDACRQLNERLAPVKAQLgPEKSkdFKEVCTAAYFARID 1146
255544848 1084 AASAFNIPLSSVFISETSTDKVPNSSPTAASASSDLYGAAVLDACEQIKARMEPVASKH-NFSS--FAELASACYVQRID 1160
302765308 1076 AATAFDIPISSVFISETSTDKVPNASPTAASASSDMYGAAVIDACNQIKERMRPLMSQ---YDS--FAKLVMACYLQRID 1150
302776502 1076 AATAFDIPISSVFISETSTDKVPNASPTAASASSDMYGAAVIDACNQIKERMRPLMSQ---YDS--FAKLVMACYLQRID 1150
219127857 1173 LTAHGFFTVDDkrCGFDWKKErpegfpddkpanswRGNPFNYFTQGVVCTEVEIDVLSGNHRTLQSDLLVDVGASINPAI 1252
115453639 1164 LSAHGFYITPD--VGFDWVSG--------------KGTPFYYFTYGAAFAEVEIDTLTGDFHTRTVDIVMDLGCSINPAI 1227
168016458 1152 LSAHGFYITPD--IGMDWDTG--------------KGRPFSYFTFGAAFAVAEIDTLTGDFHLPRVDIVMDLGHSLNPAI 1215
225435470 1164 LSAHGFYITPD--IHFDWKTG--------------KGSPFSYFTYGASFAEVEIDTLTGDFHTRVANVFLDLGHSINPAI 1227
225435472 1153 LSAHGFYITPD--IHFDWKTG--------------KGSPFSYFTYGASFAEVEIDTLTGDFHTRVANVFLDLGHSINPAI 1216
224106165 1163 LSAHGFYITPD--IGFDWTTG--------------KGNPFNYFTYGAAFAEVEIDTLTGDFHTRTANIILDLGYSINPAI 1226
255080464 1147 LSAHGWYTTPD--LVWQWDGT--------------KGRPFNYFCFGAAVSEVEIDTLSGDVNLLRTDIVMDCGDSINPAL 1210
255544848 1161 LSAHGFYITPE--IGFDWSTG--------------KGNPFRYFTYGAAFAEVEIDTLTGDFHTRAANIIMDLGYSLNPAI 1224
302765308 1151 LSAHGFYITPD--IGFDWKTG--------------KGSPFSYYTYGAACAEAEIDCLTGDSHLRRVDIVMDLGHSLNPAI 1214
302776502 1151 LSAHGFYITPD--IGFDWKTG--------------KGSPFSYYTYGAACAEAEIDCLTGDSHLRRVDIVMDLGHSLNPAI 1214
219127857 1253 DIGQIEGAFVQGMGWSTIEEVTYADDDHTWIRPrGSLFTSGPGTYKIPAFNDVPETFNVSLMDNVDNPFAVHSSKAIGEP 1332
115453639 1228 DIGQIEGGFIQGLGWAALEELKWGDDNHKWIRP-GHLFTCGPGSYKIPSVNDIPLNFKVSLLKGVLNPKVIHSSKAVGEP 1306
168016458 1216 DIGQVEGGYVQGLGWAILEELKWGDSAHPWVRP-GHLFTQGPGTYKLPTVNDIPIDFRVSLLKDAPNSKAIHSSKAVGEP 1294
225435470 1228 DVGQIEGAFVQGLGWVALEELKWGDAAHKWIPP-GCLYTCGPGSYKIPSINDVPLKFDVSLLKGAPNPKAIHSSKAVGEP 1306
225435472 1217 DVGQIEGAFVQGLGWVALEELKWGDAAHKWIPP-GCLYTCGPGSYKIPSINDVPLKFDVSLLKGAPNPKAIHSSKAVGEP 1295
224106165 1227 DVGQIEGAFVQGLGWVAIEELKWGDAAHKWIPP-GCLYTSGPGSYKIPSMNDVPFKFSVSLLKGHPNVKAIHSSKAVGEP 1305
255080464 1211 DVGQVEGGFVQGMGWVALEELKYGDPDHKWIRP-GTLFTAGPGTYKIPTANDIPLEFNVTLLHNAPNPRAVASSKAVGEP 1289
255544848 1225 DVGQIEGAFIQGLGWAALEELKWGDSAHKWIPP-GCLYTCGPGSYKIPSLNDVPFKFSVSLLKGHPNATAIHSSKAVGEP 1303
302765308 1215 DIGQIEGAFVQGLGWVALEELKWGDKAHPWIKP-GYLFTQGPGTYKLPTVNDIPIDFRVSLLKDAPNPRAIHSSKAVGEP 1293
302776502 1215 DIGQIEGAFVQGLGWVALEELKWGDKAHPWIKP-GYLFTQGPGTYKLPTVNDIPIDFRVSLLKDAPNPRAIHSSKAVGEP 1293
219127857 1333 PFFLGASVFYAIKDAVTAARSQNLGQTsYFEMRMPATSERIRMYCADPLASQAVS 1387
115453639 1307 PFFLGSAVLFAIKDAISAARAEEGHFD-WFPLDSPATPERIRMACVDSITKKFAS 1360
168016458 1295 PLFLATSALFAIKDAIKAARKDSGHNG-WFVLDTPATPERIRMACADEFTKPFAG 1348
225435470 1307 PFFLASSVFFAIKDAIVAARREVGNKD-WFPLDNPATPERVRMACLDEFAMQFVS 1360
225435472 1296 PFFLASSVFFAIKDAIVAARREVGNKD-WFPLDNPATPERVRMACLDEFAMQFVS 1349
224106165 1306 PFFLASAVFFAIKDAIIAARAEVGHHE-WFPLDNPATPERIRMACLDEFSTRFID 1359
255080464 1290 PFLLANSVFFAIKDAVCAARAGNGLDT-DITMDSPATPERVRMACGGPISDVFYD 1343
255544848 1304 PFFLASAVFFAIKDAIIAARAEVEHHE-WFPLDNPATPERIRMACLDEITARFIK 1357
302765308 1294 PLFLAAAALFAVKEAIASARAETGLHG-WFLLDTPATPERIRMACVDDITARFAS 1347
302776502 1294 PLFLAAAALFAVKEAIASARAETGLHG-WFLLDTPATPERIRMACVDDITARFAS 1347
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