Conserved Protein Domain Family
EPO_TPO

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pfam00758: EPO_TPO 
Erythropoietin/thrombopoietin
Statistics
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PSSM-Id: 459927
Aligned: 10 rows
Threshold Bit Score: 151.918
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_014315023  50 RLICDSRVLERYILEAREAENVTMGCAEGCSFSENITVPDTKVNFYAWKRMEVEQQALEVWQGLALLSEAILRGQALLAN 129
XP_003470194  30 RLICDSTVLERYIVEAKDAENVTMSCTEGCSLGENITVPDTKVNFCAWEKMGVGQQAAEVWQGLVLLSEAMLQGQALLAN 109
XP_017820320 191 HLICDSGVLERYVLEGKEAENVTMGCAESCSLNENITVPDTKVNFYAWKKMEFGQQAVDIWQGLTLLSEAVLRGQALLAN 270
XP_003768892  29 SPFCESHILERYILEAKEAQNATVACLEDCSLGENITVPDTRVNFHTWKKMEVGQKAGEVWQGLTLLSEAVLKGQALLAN 108
P42705        25 PPACDPRLLNKMLRDSHVLHSRLSQCPDIYPLSTPVLLPAVDFSLGEWKTQKEQTKAQDVWGAVALLLDGVLAARGQLGP 104 dog
XP_001376838  26 APVCDPRLFNKLLRDSAALHSRLSQCSDLSPLPIPVLLPTVDFSLREWRAKTEQTKGQEVLGAVTLLLEGAIAARGQLNP 105
1_pfamImport   1 PPACDPRLLNKLLRDSHILHSRLSQCPDFNPLSTPVPLPTVDFSLGEWKTQTEQNKAQDVLGAVTLLLEGVMAARRQVGP 80 
XP_005999842  27 RPVCDTSVMDKFIEDAKDAESFVNGCTEACELPVDMTLPATKVNIKEWNEMDNKIKEREIWAGINLFTHTFKTVRDFIRD 106
ABQ41210      15 RPICDLRVLDHFIKEAWDAEAAMRTCKDDCSIATNVTVPLTRVDFEVWEAMNIEEQAQEVQSGLHMLNEAIGSLQ----- 89 
XP_007483424  29 SPFCDSHILERYILEAKEAQNATV-----------------------------GQKAGEVWQGLTLLSEAVLKGQALLAN 79  gray short-tail...
XP_014315023 130 SSQTSETLQLHVDKAISGLRSLTSLLRALGSQKeaISLPDAtaSAIPLRTFTVDTLCKFFRIYSNFLRGKLK--LYTGEA 207
XP_003470194 110 SSQQSETLQLHLDKAVSGLRSLTSLLHLLGAQKapILPPDAa-SPAPLRTFPVDTLCKLFQVYSNFLRGKLK--LYTGMA 186
XP_017820320 271 SSQPREPLQLHMDRAVSGLRSLTTLLRALGAQKeaTSPPDAapSAVPLQTITADTFSKLFQVYSNFIRGKLK--LYAGEA 348
XP_003768892 109 SSQTPVALKLFVDKAVSSLRSLRFLLRGLGTQEeaIFVPNAp-TAVPLRTFTVGTMDKLFRIYSNFLRGKLK--LFWREA 185
P42705       105 SCLSSLLGQL--SGQVRLL--LGALQGLLGTQL----PPQG-------RTTTHKDPNAIFLSFQQLLRGKVRflLLVAGP 169 dog
XP_001376838 106 SCLSSLLGQL--SAQTHSL--LGALQGLLGTPS----LPKG-------QTIAHREPTAIFLSFQQLLRGKVRflLHAVRP 170
1_pfamImport  81 TCLSSLLEQL--SGQVRLL--LGALQGLLGTQL----PPQG-------RTTAHKDPNAIFPEFPT---AALSflLLVVGL 142
XP_005999842 107 S-----VTVYHITKSYSNTRSTAQILKRLHTQE--IPVPDS----PPQKTVVVRTLGELFHIHVNFLRGKVK--LFISDA 173
ABQ41210      90 ISNQTEVLQSHIDASIRNIASIRQVLRSLSIPE--YVPPTS--SGEDKETQKISSISELFQVHVNFLRGKAR--LLLANA 163
XP_007483424  80 SSQTPAALKLFVDKAVSSLRSLRFLLRGLRTQEetVSLPDAp-TAAPFRTFTVGTMDKLFRIYSNFLRGKLK--LFLREA 156 gray short-tail...
XP_014315023 208 --CRRG 211
XP_003470194 187 --CRRG 190
XP_017820320 349 --CRTE 352
XP_003768892 186 --CQSQ 189
P42705       170 tlCAKQ 175 dog
XP_001376838 171 llCARQ 176
1_pfamImport 143 tlCARR 148
XP_005999842 174 --CSMQ 177
ABQ41210     164 pvCRQG 169
XP_007483424 157 --CQSE 160 gray short-tailed opossum
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