7QN7: Cryo-EM structure of human full-length extrasynaptic alpha4beta3delta GABA(A)R in complex with GABA, histamine and nanobody Nb25

PDB ID: 7QN7Download
MMDB ID: 214264
PDB Deposition Date: 2021/12/20
Updated in MMDB: 2023/11
Experimental Method:
electron microscopy
Resolution: 3  Å
Source Organism:
Similar Structures:
Biological Unit for 7QN7: heptameric; determined by author
Molecular Components in 7QN7
Label Count Molecule
Proteins (7 molecules)
1
Gamma-aminobutyric Acid Receptor Subunit Alpha-4
Molecule annotation
3
Gamma-aminobutyric Acid Receptor Subunit Beta-3
Molecule annotation
1
Gamma-aminobutyric Acid Receptor Subunit Delta
Molecule annotation
2
Nanobody Nb25
Molecule annotation
Chemicals and Non-standard biopolymers (42 molecules)
1
20
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
4
beta-D-mannopyranosebeta-D-mannopyranose
3
8
alpha-D-mannopyranosealpha-D-mannopyranose
4
1
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE
5
4
DECANEDECANE
6
1
GAMMA-AMINO-BUTANOIC ACIDGAMMA-AMINO-BUTANOIC ACID
7
2
HEXADECANEHEXADECANE
8
2
HISTAMINEHISTAMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303