6Z36: Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2118

PDB ID: 6Z36Download
MMDB ID: 188097
PDB Deposition Date: 2020/5/19
Updated in MMDB: 2020/05
Experimental Method:
x-ray diffraction
Resolution: 1.37  Å
Source Organism:
Similar Structures:
Biological Unit for 6Z36: monomeric; determined by author
Molecular Components in 6Z36
Label Count Molecule
Protein (1 molecule)
1
Activin Receptor Type I
(Gene symbol: ACVR1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
3
SULFATE IONSULFATE ION
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
D(-)-TARTARIC ACIDD(-)-TARTARIC ACID
4
3
4-methyl-3-(4-piperidin-4-ylphenyl)-5-(3,4,5-trimethoxyphenyl)pyridine4-methyl-3-(4-piperidin-4-ylphenyl)-5-(3,4,5-trimethoxyphenyl)pyridine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303