6TVO: Human CRM1-RanGTP in complex with Leptomycin B

PDB ID: 6TVODownload
MMDB ID: 189819
PDB Deposition Date: 2020/1/10
Updated in MMDB: 2020/08
Experimental Method:
x-ray diffraction
Resolution: 3.201  Å
Source Organism:
Similar Structures:
Biological Unit for 6TVO: dimeric; determined by author and by software (PISA)
Molecular Components in 6TVO
Label Count Molecule
Proteins (2 molecules)
1
Gtp-binding Nuclear Protein RAN
(Gene symbol: RAN)
Molecule annotation
1
Exportin-1
(Gene symbol: XPO1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
Leptomycin B, bound formLeptomycin B, bound form
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303