6PKC: Inhibition of Human Menin by VTP-50469

PDB ID: 6PKCDownload
MMDB ID: 182354
PDB Deposition Date: 2019/6/29
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 6PKC: monomeric; determined by author
Molecular Components in 6PKC
Label Count Molecule
Protein (1 molecule)
1
Menin,menin
(Gene symbol: MEN1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
5-fluoro-2-({4-[7-({trans-4-[(methylsulfonyl)amino]cyclohexyl}methyl)-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl}oxy)-N,N-di(propan-2-yl)benzamide5-fluoro-2-({4-[7-({trans-4-[(methylsulfonyl)amino]cyclohexyl}methyl)-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl}oxy)-N,N-di(propan-2-yl)benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303