6JOJ: Crystal structure of PDGFRA T674I in complex with crenolanib by soaking

PDB ID: 6JOJDownload
MMDB ID: 185571
PDB Deposition Date: 2019/3/22
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 6JOJ: monomeric; determined by author and by software (PISA)
Molecular Components in 6JOJ
Label Count Molecule
Protein (1 molecule)
1
Platelet-derived Growth Factor Receptor Alpha
(Gene symbol: PDGFRA)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine
2
2
SULFATE IONSULFATE ION
3
7
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303