6BRJ: DDR1 bound to VX-680

PDB ID: 6BRJDownload
MMDB ID: 169280
PDB Deposition Date: 2017/11/30
Updated in MMDB: 2018/12
Experimental Method:
x-ray diffraction
Resolution: 2.231  Å
Source Organism:
Similar Structures:
Biological Unit for 6BRJ: monomeric; determined by author and by software (PISA)
Molecular Components in 6BRJ
Label Count Molecule
Protein (1 molecule)
1
Epithelial Discoidin Domain-containing Receptor 1
(Gene symbol: DDR1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDECYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303