5ZJW: Crystal Structure of PAK4 in complex with inhibitor CZg353

PDB ID: 5ZJWDownload
MMDB ID: 173776
PDB Deposition Date: 2018/3/22
Updated in MMDB: 2019/04
Experimental Method:
x-ray diffraction
Resolution: 1.798  Å
Source Organism:
Similar Structures:
Biological Unit for 5ZJW: monomeric; determined by author
Molecular Components in 5ZJW
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase PAK 4
(Gene symbol: PAK4)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
1
(3Z)-N-[(1S)-2-hydroxy-1-phenylethyl]-3-[(1H-imidazol-2-yl)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-5-carboxamide(3Z)-N-[(1S)-2-hydroxy-1-phenylethyl]-3-[(1H-imidazol-2-yl)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-5-carboxamide
2
8
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
4
1
BICARBONATE IONBICARBONATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303