5SVF: IDH1 R132H in complex with IDH125

PDB ID: 5SVFDownload
MMDB ID: 147168
PDB Deposition Date: 2016/8/5
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 2.34  Å
Source Organism:
Similar Structures:
Biological Unit for 5SVF: dimeric; determined by author and by software (PISA)
Molecular Components in 5SVF
Label Count Molecule
Proteins (2 molecules)
2
Isocitrate Dehydrogenase [nadp] Cytoplasmic
(Gene symbol: IDH1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
2
(4S)-3-(2-{[(1S)-1-phenylethyl]amino}pyrimidin-4-yl)-4-(propan-2-yl)-1,3-oxazolidin-2-one(4S)-3-(2-{[(1S)-1-phenylethyl]amino}pyrimidin-4-yl)-4-(propan-2-yl)-1,3-oxazolidin-2-one
3
2
CITRATE ANIONCITRATE ANION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303