5GRE: Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+), citrate and ADP

PDB ID: 5GREDownload
MMDB ID: 147261
PDB Deposition Date: 2016/8/11
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.65  Å
Source Organism:
Similar Structures:
Biological Unit for 5GRE: dimeric; determined by author and by software (PISA)
Molecular Components in 5GRE
Label Count Molecule
Proteins (2 molecules)
1
Isocitrate Dehydrogenase [nad] Subunit Alpha, Mitochondrial
(Gene symbol: IDH3A)
Molecule annotation
1
Isocitrate Dehydrogenase [nad] Subunit Gamma, Mitochondrial
(Gene symbol: IDH3G)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
1
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
3
1
CITRIC ACIDCITRIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303