4OG7: Human menin with bound inhibitor MIV-7

PDB ID: 4OG7Download
MMDB ID: 118104
PDB Deposition Date: 2014/1/15
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.08  Å
Source Organism:
Similar Structures:
Biological Unit for 4OG7: monomeric; determined by author and by software (PISA)
Molecular Components in 4OG7
Label Count Molecule
Protein (1 molecule)
1
Menin
(Gene symbol: MEN1)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
SULFATE IONSULFATE ION
2
1
4-(3-{4-[(S)-cyclopentyl(hydroxy)pyridin-2-ylmethyl]piperidin-1-yl}propoxy)benzenesulfonamide4-(3-{4-[(S)-cyclopentyl(hydroxy)pyridin-2-ylmethyl]piperidin-1-yl}propoxy)benzenesulfonamide
3
1
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
4
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
4
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303