NCBI Conserved Domain Search

Ankyrin repeat [Signal transduction mechanisms];

25-287

2.91e-50

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 179.38 E-value: 2.91e-50

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  25 LNFLFYLEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLL 104
Cdd:COG0666    28 AALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLL 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 105 SRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGN 184
Cdd:COG0666   108 EAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGE 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 185 TPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALcLELLVGNGADVNMKSKDGKTPLHMTALHGRFS 264
Cdd:COG0666   188 TPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEI-VKLLLEAGADLNAKDKDGLTALLLAAAAGAAL 266

                         250       260
                  ....*....|....*....|...
gi 1370483583 265 RSQTIIQSGAVIDCEDKNGNTPL 287
Cdd:COG0666   267 IVKLLLLALLLLAAALLDLLTLL 289

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

484-721

7.19e-39

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 146.64 E-value: 7.19e-39

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 484 DMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYiLKRT 563
Cdd:COG0666    44 LLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDK-DGET 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 564 PIHAAATNGHSECLRLLIGNaepqNA-VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGH 642
Cdd:COG0666   123 PLHLAAYNGNLEIVKLLLEA----GAdVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGH 198

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370483583 643 EECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAasmdANPATADNHGYTALHWACYNGHETCVELLLE 721
Cdd:COG0666   199 LEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAG----ADLNAKDKDGLTALLLAAAAGAALIVKLLLL 273

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

681-925

1.41e-34

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 134.31 E-value: 1.41e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 681 ALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVF-QKTEGNAFSPLHCAVINDNEGAAEMLIDtLGASi 759
Cdd:COG0666    35 LLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADiNAKDDGGNTLLHAAARNGDLEIVKLLLE-AGAD- 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 760 VNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSsASAELTLQDNSKNTALH 839
Cdd:COG0666   113 VNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLE-AGADVNARDNDGETPLH 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 840 LACSKGHETSALLILEKITDrnlINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADC 919
Cdd:COG0666   192 LAAENGHLEIVKLLLEAGAD---VNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIV 268


                  ....*.
gi 1370483583 920 LALILA 925
Cdd:COG0666   269 KLLLLA 274

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

169-447

1.60e-33

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 131.23 E-value: 1.60e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 169 LLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSK 248
Cdd:COG0666     6 LLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDD 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 249 DGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGF 328
Cdd:COG0666    86 GGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGN 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 329 SDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASV 408
Cdd:COG0666   166 LEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADL 245

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1370483583 409 NDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDK 447
Cdd:COG0666   246 NAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLD 284

Name

Accession

Description

Interval

E-value

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

25-287

2.91e-50

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 179.38 E-value: 2.91e-50

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  25 LNFLFYLEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLL 104
Cdd:COG0666    28 AALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLL 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 105 SRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGN 184
Cdd:COG0666   108 EAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGE 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 185 TPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALcLELLVGNGADVNMKSKDGKTPLHMTALHGRFS 264
Cdd:COG0666   188 TPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEI-VKLLLEAGADLNAKDKDGLTALLLAAAAGAAL 266

                         250       260
                  ....*....|....*....|...
gi 1370483583 265 RSQTIIQSGAVIDCEDKNGNTPL 287
Cdd:COG0666   267 IVKLLLLALLLLAAALLDLLTLL 289

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

484-721

7.19e-39

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 146.64 E-value: 7.19e-39

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 484 DMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYiLKRT 563
Cdd:COG0666    44 LLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDK-DGET 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 564 PIHAAATNGHSECLRLLIGNaepqNA-VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGH 642
Cdd:COG0666   123 PLHLAAYNGNLEIVKLLLEA----GAdVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGH 198

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370483583 643 EECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAasmdANPATADNHGYTALHWACYNGHETCVELLLE 721
Cdd:COG0666   199 LEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAG----ADLNAKDKDGLTALLLAAAAGAALIVKLLLL 273

PHA03100

ankyrin repeat protein; Provisional

34-245

1.46e-35

ankyrin repeat protein; Provisional

Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 140.57 E-value: 1.46e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  34 VQVLLKHSADVNARDKNWQTPLHIAAANKAV-----KCAEALVPLLSNVNVSDRAGRTALHHAAF--SGHGEMVKLLLSR 106
Cdd:PHA03100   51 VKILLDNGADINSSTKNNSTPLHYLSNIKYNltdvkEIVKLLLEYGANVNAPDNNGITPLLYAISkkSNSYSIVEYLLDN 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 107 GANINAFDKKDRRAIHWAAYMGHI--EVVKLLVSHGAEVTCKDKksytplhaaassgmisvVKYLLDLGVDMNEPNAYGN 184
Cdd:PHA03100  131 GANVNIKNSDGENLLHLYLESNKIdlKILKLLIDKGVDINAKNR-----------------VNYLLSYGVPINIKDVYGF 193

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370483583 185 TPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALcLELLVGNGADVNM 245
Cdd:PHA03100  194 TPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEI-FKLLLNNGPSIKT 253

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

681-925

1.41e-34

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 134.31 E-value: 1.41e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 681 ALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVF-QKTEGNAFSPLHCAVINDNEGAAEMLIDtLGASi 759
Cdd:COG0666    35 LLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADiNAKDDGGNTLLHAAARNGDLEIVKLLLE-AGAD- 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 760 VNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSsASAELTLQDNSKNTALH 839
Cdd:COG0666   113 VNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLE-AGADVNARDNDGETPLH 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 840 LACSKGHETSALLILEKITDrnlINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADC 919
Cdd:COG0666   192 LAAENGHLEIVKLLLEAGAD---VNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIV 268


                  ....*.
gi 1370483583 920 LALILA 925
Cdd:COG0666   269 KLLLLA 274

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

169-447

1.60e-33

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 131.23 E-value: 1.60e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 169 LLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSK 248
Cdd:COG0666     6 LLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDD 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 249 DGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGF 328
Cdd:COG0666    86 GGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGN 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 329 SDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASV 408
Cdd:COG0666   166 LEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADL 245

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1370483583 409 NDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDK 447
Cdd:COG0666   246 NAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLD 284

PHA03095

ankyrin-like protein; Provisional

163-419

2.60e-31

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 128.99 E-value: 2.60e-31

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 163 ISVVKYLLDLGVDMNEPNAYGNTPLHV--ACYNGQDV-VVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGN 239
Cdd:PHA03095   27 VEEVRRLLAAGADVNFRGEYGKTPLHLylHYSSEKVKdIVRLLLEAGADVNAPERCGFTPLHLYLYNATTLDVIKLLIKA 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 240 GADVNMKSKDGKTPLH--MTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGH---ELLiNTLITSGADTAKRGI 314
Cdd:PHA03095  107 GADVNAKDKVGRTPLHvyLSGFNINPKVIRLLLRKGADVNALDLYGMTPLAVLLKSRNanvELL-RLLIDAGADVYAVDD 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 315 HGMFPLHLAALS--GFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLL--NTGADFNKKDKFGRSPLHYAA 390
Cdd:PHA03095  186 RFRSLLHHHLQSfkPRARIVRELIRAGCDPAATDMLGNTPLHSMATGSSCKRSLVLPllIAGISINARNRYGQTPLHYAA 265

                         250       260       270
                  ....*....|....*....|....*....|
gi 1370483583 391 ANCNyQCLFA-LVGSGASVNDLDERGCTPL 419
Cdd:PHA03095  266 VFNN-PRACRrLIALGADINAVSSDGNTPL 294

PHA02874

ankyrin repeat protein; Provisional

498-807

7.99e-23

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 102.73 E-value: 7.99e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 498 LHLAAYHGHHQALEVLVQS---LLDLDVRNSSgrTPLDLAAFKGHVECVDVLINQGASIlvkDYILKRTP--IHAAATNG 572
Cdd:PHA02874    5 LRMCIYSGDIEAIEKIIKNkgnCINISVDETT--TPLIDAIRSGDAKIVELFIKHGADI---NHINTKIPhpLLTAIKIG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 573 HSECLRLLIgnaepQNAVDIQdgngqtplMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQH 652
Cdd:PHA02874   80 AHDIIKLLI-----DNGVDTS--------ILPIPCIEKDMIKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEY 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 653 GAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDANpataDNHGYTALHWACYNGHETCVELLLEQ--EVFQKTEg 730
Cdd:PHA02874  147 GADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVK----DNNGESPLHNAAEYGDYACIKLLIDHgnHIMNKCK- 221

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370483583 731 NAFSPLHCAVINdNEGAAEMLIDTlgASIvNATDSKGRTPLH-AAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMA 807
Cdd:PHA02874  222 NGFTPLHNAIIH-NRSAIELLINN--ASI-NDQDIDGSTPLHhAINPPCDIDIIDILLYHKADISIKDNKGENPIDTA 295

Ank_2

Ankyrin repeats (3 copies);

88-180

5.35e-21

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 88.25 E-value: 5.35e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  88 LHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHgAEVTCKDKKsYTPLHAAASSGMISVVK 167
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDNG-RTALHYAARSGHLEIVK 78

                          90
                  ....*....|...
gi 1370483583 168 YLLDLGVDMNEPN 180
Cdd:pfam12796  79 LLLEKGADINVKD 91

PHA03095

ankyrin-like protein; Provisional

597-926

2.41e-19

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 92.40 E-value: 2.41e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 597 GQTPLMLSVLNGHTDC---VYSLLNKGANVDAKDKWGRTALH---RGAVTghEECVDALLQHGAKCLLRDSRGRTPIH-- 668
Cdd:PHA03095   47 GKTPLHLYLHYSSEKVkdiVRLLLEAGADVNAPERCGFTPLHlylYNATT--LDVIKLLIKAGADVNAKDKVGRTPLHvy 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 669 LSAACGHIGVLGALLQsaasMDANPATADNHGYTalhwacynghetcvellleqevfqktegnafsPLHCAVINdnegaa 748
Cdd:PHA03095  125 LSGFNINPKVIRLLLR----KGADVNALDLYGMT--------------------------------PLAVLLKS------ 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 749 emlidtlgasiVNATdskgrtplhaaaftdhVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNT--VEMLVSsASAE 826
Cdd:PHA03095  163 -----------RNAN----------------VELLRLLIDAGADVYAVDDRFRSLLHHHLQSFKPRAriVRELIR-AGCD 214

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 827 LTLQDNSKNTALHLACSKGHETSALLI--LEKITDrnlINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGY 904
Cdd:PHA03095  215 PAATDMLGNTPLHSMATGSSCKRSLVLplLIAGIS---INARNRYGQTPLHYAAVFNNPRACRRLIALGADINAVSSDGN 291

                         330       340
                  ....*....|....*....|..
gi 1370483583 905 TPALACAPNKDVaDCLALILAT 926
Cdd:PHA03095  292 TPLSLMVRNNNG-RAVRAALAK 312

Ank_2

Ankyrin repeats (3 copies);

565-660

1.75e-18

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 81.32 E-value: 1.75e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 565 IHAAATNGHSECLRLLIgnaEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKgANVDAKDKwGRTALHRGAVTGHEE 644
Cdd:pfam12796   1 LHLAAKNGNLELVKLLL---ENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDN-GRTALHYAARSGHLE 75

                          90
                  ....*....|....*.
gi 1370483583 645 CVDALLQHGAKCLLRD 660
Cdd:pfam12796  76 IVKLLLEKGADINVKD 91

Ank_2

Ankyrin repeats (3 copies);

771-864

1.30e-16

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 75.92 E-value: 1.30e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 771 LHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELtlqDNSKNTALHLACSKGHETSA 850
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVNL---KDNGRTALHYAARSGHLEIV 77

                          90
                  ....*....|....
gi 1370483583 851 LLILEKITDRNLIN 864
Cdd:pfam12796  78 KLLLEKGADINVKD 91

Ank_2

Ankyrin repeats (3 copies);

254-346

7.74e-13

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 65.14 E-value: 7.74e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 254 LHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGAdtAKRGIHGMFPLHLAALSGFSDCCR 333
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHAD--VNLKDNGRTALHYAARSGHLEIVK 78

                          90
                  ....*....|...
gi 1370483583 334 KLLSSGFDIDTPD 346
Cdd:pfam12796  79 LLLEKGADINVKD 91

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

31-203

1.70e-12

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 71.20 E-value: 1.70e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  31 LEAVQVLLK-HSADVNARDKNWQTPLHIAAANKAVKCAEAL---VPLLSNVNV-SD-RAGRTALHHAAFSGHGEMVKLLL 104
Cdd:cd22192    30 VQAIKKLLKcPSCDLFQRGALGETALHVAALYDNLEAAVVLmeaAPELVNEPMtSDlYQGETALHIAVVNQNLNLVRELI 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 105 SRGANIN-------AFDKKDRRAIHW-------AAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLL 170
Cdd:cd22192   110 ARGADVVspratgtFFRPGPKNLIYYgehplsfAACVGNEEIVRLLIEHGADIRAQDSLGNTVLHILVLQPNKTFACQMY 189

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1370483583 171 DLGVDMNE----------PNAYGNTPLHVACYNGQDVVVNELI 203
Cdd:cd22192   190 DLILSYDKeddlqpldlvPNNQGLTPFKLAAKEGNIVMFQHLV 232

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

529-669

1.52e-09

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 61.95 E-value: 1.52e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 529 TPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNA-----EPQNAVDIQdgnGQTPLML 603
Cdd:cd22192    19 SPLLLAAKENDVQAIKKLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAApelvnEPMTSDLYQ---GETALHI 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 604 SVLNGHTDCVYSLLNKGANV--------------DAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHL 669
Cdd:cd22192    96 AVVNQNLNLVRELIARGADVvspratgtffrpgpKNLIYYGEHPLSFAACVGNEEIVRLLIEHGADIRAQDSLGNTVLHI 175

trp

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ...

518-741

4.27e-08

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family (TC. 1.A.4)The TRP-CC family has also been called the store-operated calcium channel (SOC) family. The prototypical members include the Drosophila retinal proteinsTRP and TRPL (Montell and Rubin, 1989; Hardie and Minke, 1993). SOC members of the family mediate the entry of extracellular Ca2+ into cells in responseto depletion of intracellular Ca2+ stores (Clapham, 1996) and agonist stimulated production of inositol-1,4,5 trisphosphate (IP3). One member of the TRP-CCfamily, mammalian Htrp3, has been shown to form a tight complex with the IP3 receptor (TC #1.A.3.2.1). This interaction is apparently required for IP3 tostimulate Ca2+ release via Htrp3. The vanilloid receptor subtype 1 (VR1), which is the receptor for capsaicin (the ?hot? ingredient in chili peppers) and servesas a heat-activated ion channel in the pain pathway (Caterina et al., 1997), is also a member of this family. The stretch-inhibitable non-selective cation channel(SIC) is identical to the vanilloid receptor throughout all of its first 700 residues, but it exhibits a different sequence in its last 100 residues. VR1 and SICtransport monovalent cations as well as Ca2+. VR1 is about 10x more permeable to Ca2+ than to monovalent ions. Ca2+ overload probably causes cell deathafter chronic exposure to capsaicin. (McCleskey and Gold, 1999). [Transport and binding proteins, Cations and iron carrying compounds]

Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 57.40 E-value: 4.27e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 518 LDLDVRNSSGRTPLDLAAFKG-HVECVDVLINQGASILVKDyilkrTPIHAAATNGH---SECLRLLIGNAE----PQNA 589
Cdd:TIGR00870  43 LNINCPDRLGRSALFVAAIENeNLELTELLLNLSCRGAVGD-----TLLHAISLEYVdavEAILLHLLAAFRksgpLELA 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 590 VDIQDGN---GQTPLMLSVLNGHTDCVYSLLNKGANVDAKDK--------------WGRTALHRGAVTGHEECVDALLQH 652
Cdd:TIGR00870 118 NDQYTSEftpGITALHLAAHRQNYEIVKLLLERGASVPARACgdffvksqgvdsfyHGESPLNAAACLGSPSIVALLSED 197

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 653 GAKCLLRDSRGRTPIHLSAACGHIGVLGALL-----QSAASMDANPATAD------NH-GYTALHWACYNGHETCVELLL 720
Cdd:TIGR00870 198 PADILTADSLGNTLLHLLVMENEFKAEYEELscqmyNFALSLLDKLRDSKelevilNHqGLTPLKLAAKEGRIVLFRLKL 277

                         250       260
                  ....*....|....*....|..
gi 1370483583 721 EQEVFQKT-EGNAFSPLHCAVI 741
Cdd:TIGR00870 278 AIKYKQKKfVAWPNGQQLLSLY 299

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

649-822

6.36e-08

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 56.56 E-value: 6.36e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 649 LLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDANPATADNH-GYTALHWACYNGHETCVELLLEQ----- 722
Cdd:cd22192    37 LKCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAAPELVNEPMTSDLYqGETALHIAVVNQNLNLVRELIARgadvv 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 723 ------EVFQKTEGNAF----SPLHCAVINDNEGAAEMLIDTlGASIVnATDSKGRTPLHAAAF----TDHVECLQLLLS 788
Cdd:cd22192   117 spratgTFFRPGPKNLIyygeHPLSFAACVGNEEIVRLLIEH-GADIR-AQDSLGNTVLHILVLqpnkTFACQMYDLILS 194

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1370483583 789 HNAQVNSV------DSTGKTPLMMAAENGQTNTVEMLVSS 822
Cdd:cd22192   195 YDKEDDLQpldlvpNNQGLTPFKLAAKEGNIVMFQHLVQK 234

trp

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ...

31-191

1.16e-06

Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 52.78 E-value: 1.16e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  31 LEAVQVLLKHSADVNARDknwqTPLHIAAANKAVKCAEALVPLLSN---------VNVSDR----AGRTALHHAAFSGHG 97
Cdd:TIGR00870  66 LELTELLLNLSCRGAVGD----TLLHAISLEYVDAVEAILLHLLAAfrksgplelANDQYTseftPGITALHLAAHRQNY 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  98 EMVKLLLSRGANINA------FDKKDRRA--------IHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAA----- 158
Cdd:TIGR00870 142 EIVKLLLERGASVPAracgdfFVKSQGVDsfyhgespLNAAACLGSPSIVALLSEDPADILTADSLGNTLLHLLVmenef 221

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1370483583 159 -------SSGMISVVKYLLDLGVDMNE----PNAYGNTPLHVAC 191
Cdd:TIGR00870 222 kaeyeelSCQMYNFALSLLDKLRDSKEleviLNHQGLTPLKLAA 265

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

218-423

1.36e-06

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 52.32 E-value: 1.36e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 218 TPLhFAAASTHGALCLE-LLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGA-----VIDCEDKNGNTPLHIAA 291
Cdd:cd22192    19 SPL-LLAAKENDVQAIKkLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAAPelvnePMTSDLYQGETALHIAV 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 292 RYGHELLINTLITSGADTAKRGIHGMFplhlaalsgFSDCCRKLLSsgfdidtpddFGRTCLHAAAAGGNLECLNLLLNT 371
Cdd:cd22192    98 VNQNLNLVRELIARGADVVSPRATGTF---------FRPGPKNLIY----------YGEHPLSFAACVGNEEIVRLLIEH 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370483583 372 GADFNKKDKFGRSPLHYAA--ANCNYQC-----LFALVGSGASVNdLD----ERGCTPLHYAA 423
Cdd:cd22192   159 GADIRAQDSLGNTVLHILVlqPNKTFACqmydlILSYDKEDDLQP-LDlvpnNQGLTPFKLAA 220

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

84-112

1.72e-05

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 42.19 E-value: 1.72e-05

                           10        20
                   ....*....|....*....|....*....
gi 1370483583   84 GRTALHHAAFSGHGEMVKLLLSRGANINA 112
Cdd:smart00248   2 GRTPLHLAAENGNLEVVKLLLDKGADINA 30

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

766-794

5.12e-04

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 38.34 E-value: 5.12e-04

                           10        20
                   ....*....|....*....|....*....
gi 1370483583  766 KGRTPLHAAAFTDHVECLQLLLSHNAQVN 794
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLDKGADIN 29

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

282-308

1.04e-03

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 37.18 E-value: 1.04e-03

                           10        20
                   ....*....|....*....|....*..
gi 1370483583  282 NGNTPLHIAARYGHELLINTLITSGAD 308
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLDKGAD 27

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

699-721

1.20e-03

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 37.18 E-value: 1.20e-03

                           10        20
                   ....*....|....*....|...
gi 1370483583  699 HGYTALHWACYNGHETCVELLLE 721
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLD 23

trp

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ...

335-515

4.20e-03

Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 41.22 E-value: 4.20e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 335 LLSSGFDIDTpddfGRTCLHAA-----------------AAGGNLECLNLLLNTGADFNkkdkFGRSPLHYAAANCNYQC 397
Cdd:TIGR00870  72 LLNLSCRGAV----GDTLLHAIsleyvdaveaillhllaAFRKSGPLELANDQYTSEFT----PGITALHLAAHRQNYEI 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 398 LFALVGSGASVN--------------DLDERGCTPLH-YAATSDTDgkCLEYLLRNDANPGIRDKQGYNAVH-------Y 455
Cdd:TIGR00870 144 VKLLLERGASVParacgdffvksqgvDSFYHGESPLNaAACLGSPS--IVALLSEDPADILTADSLGNTLLHllvmeneF 221

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370483583 456 SAAYGH--RLCLQLIasetpLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQ 515
Cdd:TIGR00870 222 KAEYEElsCQMYNFA-----LSLLDKLRDSKELEVILNHQGLTPLKLAAKEGRIVLFRLKLA 278

trp

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ...

710-890

8.81e-03

Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 40.06 E-value: 8.81e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 710 NGHETCVELLLEQEVFQKTEGNAfspLHCAVINDnEGAAEMLI--------DTLGASIVNATD----SKGRTPLHAAAFT 777
Cdd:TIGR00870  63 NENLELTELLLNLSCRGAVGDTL---LHAISLEY-VDAVEAILlhllaafrKSGPLELANDQYtsefTPGITALHLAAHR 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 778 DHVECLQLLLSHNAQVNS------------VDST--GKTPLMMAAENGQTNTVEMLvSSASAELTLQDNSKNTALHL--- 840
Cdd:TIGR00870 139 QNYEIVKLLLERGASVPAracgdffvksqgVDSFyhGESPLNAAACLGSPSIVALL-SEDPADILTADSLGNTLLHLlvm 217

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 841 ---------ACSKGHETSALLILEKITD-RNLINATNAALQTPLHVAARNGLTMVVQELL 890
Cdd:TIGR00870 218 enefkaeyeELSCQMYNFALSLLDKLRDsKELEVILNHQGLTPLKLAAKEGRIVLFRLKL 277

Name

Accession

Description

Interval

E-value

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

25-287

2.91e-50

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 179.38 E-value: 2.91e-50

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  25 LNFLFYLEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLL 104
Cdd:COG0666    28 AALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLL 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 105 SRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGN 184
Cdd:COG0666   108 EAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGE 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 185 TPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALcLELLVGNGADVNMKSKDGKTPLHMTALHGRFS 264
Cdd:COG0666   188 TPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEI-VKLLLEAGADLNAKDKDGLTALLLAAAAGAAL 266

                         250       260
                  ....*....|....*....|...
gi 1370483583 265 RSQTIIQSGAVIDCEDKNGNTPL 287
Cdd:COG0666   267 IVKLLLLALLLLAAALLDLLTLL 289

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

31-312

2.78e-49

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 176.68 E-value: 2.78e-49

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  31 LEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANI 110
Cdd:COG0666     1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 111 NAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVA 190
Cdd:COG0666    81 NAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 191 CYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALcLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTII 270
Cdd:COG0666   161 AANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEI-VKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLL 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1370483583 271 QSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKR 312
Cdd:COG0666   240 EAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAA 281

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

484-721

7.19e-39

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 146.64 E-value: 7.19e-39

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 484 DMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYiLKRT 563
Cdd:COG0666    44 LLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDK-DGET 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 564 PIHAAATNGHSECLRLLIGNaepqNA-VDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGH 642
Cdd:COG0666   123 PLHLAAYNGNLEIVKLLLEA----GAdVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGH 198

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370483583 643 EECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAasmdANPATADNHGYTALHWACYNGHETCVELLLE 721
Cdd:COG0666   199 LEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAG----ADLNAKDKDGLTALLLAAAAGAALIVKLLLL 273

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

98-419

9.99e-38

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 143.17 E-value: 9.99e-38

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  98 EMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMN 177
Cdd:COG0666     2 LLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADIN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 178 EPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALcLELLVGNGADVNMKskdgktplhmt 257
Cdd:COG0666    82 AKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEI-VKLLLEAGADVNAQ----------- 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 258 alhgrfsrsqtiiqsgavidceDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLS 337
Cdd:COG0666   150 ----------------------DNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLE 207

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 338 SGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCT 417
Cdd:COG0666   208 AGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLT 287


                  ..
gi 1370483583 418 PL 419
Cdd:COG0666   288 LL 289

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

546-870

1.44e-37

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 142.79 E-value: 1.44e-37

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 546 LINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDA 625
Cdd:COG0666     3 LLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 626 KDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSaasmDANPATADNHGYTALH 705
Cdd:COG0666    83 KDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEA----GADVNAQDNDGNTPLH 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 706 WACYNGHETCVELLLEQevfqktegnafsplhcavindneGAaemlidtlgasIVNATDSKGRTPLHAAAFTDHVECLQL 785
Cdd:COG0666   159 LAAANGNLEIVKLLLEA-----------------------GA-----------DVNARDNDGETPLHLAAENGHLEIVKL 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 786 LLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVsSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINA 865
Cdd:COG0666   205 LLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLL-EAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALL 283


                  ....*
gi 1370483583 866 TNAAL 870
Cdd:COG0666   284 DLLTL 288

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

577-907

4.36e-37

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 141.63 E-value: 4.36e-37

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 577 LRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKC 656
Cdd:COG0666     1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 657 LLRDSRGRTPIHLSAACGHIGVLGALLQSaasmDANPATADNHGYTALHWACYNGHETCVELLLEQevfqktegnafspl 736
Cdd:COG0666    81 NAKDDGGNTLLHAAARNGDLEIVKLLLEA----GADVNARDKDGETPLHLAAYNGNLEIVKLLLEA-------------- 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 737 hcavindnegaaemlidtlGASiVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTV 816
Cdd:COG0666   143 -------------------GAD-VNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIV 202

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 817 EMLVsSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDrnlINATNAALQTPLHVAARNGLTMVVQELLGKGASV 896
Cdd:COG0666   203 KLLL-EAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGAD---LNAKDKDGLTALLLAAAAGAALIVKLLLLALLLL 278

                         330
                  ....*....|.
gi 1370483583 897 LAVDENGYTPA 907
Cdd:COG0666   279 AAALLDLLTLL 289

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

451-698

7.89e-37

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 140.86 E-value: 7.89e-37

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 451 NAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTP 530
Cdd:COG0666    44 LLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETP 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 531 LDLAAFKGHVECVDVLINQGASILVKDyILKRTPIHAAATNGHSECLRLLIGNaepqNA-VDIQDGNGQTPLMLSVLNGH 609
Cdd:COG0666   124 LHLAAYNGNLEIVKLLLEAGADVNAQD-NDGNTPLHLAAANGNLEIVKLLLEA----GAdVNARDNDGETPLHLAAENGH 198

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 610 TDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASM 689
Cdd:COG0666   199 LEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLL 278


                  ....*....
gi 1370483583 690 DANPATADN 698
Cdd:COG0666   279 AAALLDLLT 287

PHA03100

ankyrin repeat protein; Provisional

34-245

1.46e-35

ankyrin repeat protein; Provisional

Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 140.57 E-value: 1.46e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  34 VQVLLKHSADVNARDKNWQTPLHIAAANKAV-----KCAEALVPLLSNVNVSDRAGRTALHHAAF--SGHGEMVKLLLSR 106
Cdd:PHA03100   51 VKILLDNGADINSSTKNNSTPLHYLSNIKYNltdvkEIVKLLLEYGANVNAPDNNGITPLLYAISkkSNSYSIVEYLLDN 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 107 GANINAFDKKDRRAIHWAAYMGHI--EVVKLLVSHGAEVTCKDKksytplhaaassgmisvVKYLLDLGVDMNEPNAYGN 184
Cdd:PHA03100  131 GANVNIKNSDGENLLHLYLESNKIdlKILKLLIDKGVDINAKNR-----------------VNYLLSYGVPINIKDVYGF 193

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370483583 185 TPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALcLELLVGNGADVNM 245
Cdd:PHA03100  194 TPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEI-FKLLLNNGPSIKT 253

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

681-925

1.41e-34

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 134.31 E-value: 1.41e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 681 ALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVF-QKTEGNAFSPLHCAVINDNEGAAEMLIDtLGASi 759
Cdd:COG0666    35 LLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADiNAKDDGGNTLLHAAARNGDLEIVKLLLE-AGAD- 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 760 VNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSsASAELTLQDNSKNTALH 839
Cdd:COG0666   113 VNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLE-AGADVNARDNDGETPLH 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 840 LACSKGHETSALLILEKITDrnlINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADC 919
Cdd:COG0666   192 LAAENGHLEIVKLLLEAGAD---VNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIV 268


                  ....*.
gi 1370483583 920 LALILA 925
Cdd:COG0666   269 KLLLLA 274

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

169-447

1.60e-33

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 131.23 E-value: 1.60e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 169 LLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSK 248
Cdd:COG0666     6 LLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDD 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 249 DGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGF 328
Cdd:COG0666    86 GGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGN 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 329 SDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASV 408
Cdd:COG0666   166 LEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADL 245

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1370483583 409 NDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDK 447
Cdd:COG0666   246 NAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLD 284

PHA03095

ankyrin-like protein; Provisional

30-254

8.49e-33

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 133.23 E-value: 8.49e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  30 YLEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVkcaEALVPLL----SNVNVSDRAGRTALH-HAA-FSGHGEMVKLL 103
Cdd:PHA03095   62 VKDIVRLLLEAGADVNAPERCGFTPLHLYLYNATT---LDVIKLLikagADVNAKDKVGRTPLHvYLSgFNINPKVIRLL 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 104 LSRGANINAFDKKDRRAIHwaAYMGH----IEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMIS--VVKYLLDLGVDMN 177
Cdd:PHA03095  139 LRKGADVNALDLYGMTPLA--VLLKSrnanVELLRLLIDAGADVYAVDDRFRSLLHHHLQSFKPRarIVRELIRAGCDPA 216

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370483583 178 EPNAYGNTPLHVACYNG--QDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGnGADVNMKSKDGKTPL 254
Cdd:PHA03095  217 ATDMLGNTPLHSMATGSscKRSLVLPLLIAGISINARNRYGQTPLHYAAVFNNPRACRRLIAL-GADINAVSSDGNTPL 294

PHA03095

ankyrin-like protein; Provisional

30-303

1.48e-32

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 132.46 E-value: 1.48e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  30 YLEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLL---SNVNVSDRAGRTALH-HAAFSGHGEMVKLLLS 105
Cdd:PHA03095   26 TVEEVRRLLAAGADVNFRGEYGKTPLHLYLHYSSEKVKDIVRLLLeagADVNAPERCGFTPLHlYLYNATTLDVIKLLIK 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 106 RGANINAFDKKDRRAIHwaAYMG----HIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISV--VKYLLDLGVDMNEP 179
Cdd:PHA03095  106 AGADVNAKDKVGRTPLH--VYLSgfniNPKVIRLLLRKGADVNALDLYGMTPLAVLLKSRNANVelLRLLIDAGADVYAV 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 180 NAYGNTPLHVACYNGQD--VVVNELIDCGAIVNQKNEKGFTPLHFAAA-STHGALCLELLVGNGADVNMKSKDGKTPLHM 256
Cdd:PHA03095  184 DDRFRSLLHHHLQSFKPraRIVRELIRAGCDPAATDMLGNTPLHSMATgSSCKRSLVLPLLIAGISINARNRYGQTPLHY 263

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1370483583 257 TALHGR---FSRsqtIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLI 303
Cdd:PHA03095  264 AAVFNNpraCRR---LIALGADINAVSSDGNTPLSLMVRNNNGRAVRAAL 310

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

681-925

3.45e-32

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 127.38 E-value: 3.45e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 681 ALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVFQKTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIv 760
Cdd:COG0666     2 LLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 761 NATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVsSASAELTLQDNSKNTALHL 840
Cdd:COG0666    81 NAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLL-EAGADVNAQDNDGNTPLHL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 841 ACSKGHETSALLILEKITDrnlINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCL 920
Cdd:COG0666   160 AAANGNLEIVKLLLEAGAD---VNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVK 236


                  ....*
gi 1370483583 921 ALILA 925
Cdd:COG0666   237 LLLEA 241

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

207-469

1.54e-31

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 125.45 E-value: 1.54e-31

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 207 AIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTP 286
Cdd:COG0666    11 LLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTL 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 287 LHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLN 366
Cdd:COG0666    91 LHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVK 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 367 LLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDtDGKCLEYLLRNDANPGIRD 446
Cdd:COG0666   171 LLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENG-NLEIVKLLLEAGADLNAKD 249

                         250       260
                  ....*....|....*....|...
gi 1370483583 447 KQGYNAVHYSAAYGHRLCLQLIA 469
Cdd:COG0666   250 KDGLTALLLAAAAGAALIVKLLL 272

PHA03095

ankyrin-like protein; Provisional

163-419

2.60e-31

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 128.99 E-value: 2.60e-31

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 163 ISVVKYLLDLGVDMNEPNAYGNTPLHV--ACYNGQDV-VVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGN 239
Cdd:PHA03095   27 VEEVRRLLAAGADVNFRGEYGKTPLHLylHYSSEKVKdIVRLLLEAGADVNAPERCGFTPLHLYLYNATTLDVIKLLIKA 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 240 GADVNMKSKDGKTPLH--MTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGH---ELLiNTLITSGADTAKRGI 314
Cdd:PHA03095  107 GADVNAKDKVGRTPLHvyLSGFNINPKVIRLLLRKGADVNALDLYGMTPLAVLLKSRNanvELL-RLLIDAGADVYAVDD 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 315 HGMFPLHLAALS--GFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLL--NTGADFNKKDKFGRSPLHYAA 390
Cdd:PHA03095  186 RFRSLLHHHLQSfkPRARIVRELIRAGCDPAATDMLGNTPLHSMATGSSCKRSLVLPllIAGISINARNRYGQTPLHYAA 265

                         250       260       270
                  ....*....|....*....|....*....|
gi 1370483583 391 ANCNyQCLFA-LVGSGASVNDLDERGCTPL 419
Cdd:PHA03095  266 VFNN-PRACRrLIALGADINAVSSDGNTPL 294

PHA03095

ankyrin-like protein; Provisional

130-398

8.70e-31

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 127.45 E-value: 8.70e-31

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 130 IEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGM---ISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDV-VVNELIDC 205
Cdd:PHA03095   27 VEEVRRLLAAGADVNFRGEYGKTPLHLYLHYSSekvKDIVRLLLEAGADVNAPERCGFTPLHLYLYNATTLdVIKLLIKA 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 206 GAIVNQKNEKGFTPLH--FAAASTHgALCLELLVGNGADVNMKSKDGKTPLHMtalhgrFSRSQTI--------IQSGAV 275
Cdd:PHA03095  107 GADVNAKDKVGRTPLHvyLSGFNIN-PKVIRLLLRKGADVNALDLYGMTPLAV------LLKSRNAnvellrllIDAGAD 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 276 IDCEDKNGNTPLHIAARYGH--ELLINTLITSGADTAKRGIHGMFPLHLAALsgFSDCCR----KLLSSGFDIDTPDDFG 349
Cdd:PHA03095  180 VYAVDDRFRSLLHHHLQSFKprARIVRELIRAGCDPAATDMLGNTPLHSMAT--GSSCKRslvlPLLIAGISINARNRYG 257

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1370483583 350 RTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCL 398
Cdd:PHA03095  258 QTPLHYAAVFNNPRACRRLIALGADINAVSSDGNTPLSLMVRNNNGRAV 306

PHA02876

ankyrin repeat protein; Provisional

99-419

1.43e-30

ankyrin repeat protein; Provisional

Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 129.03 E-value: 1.43e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  99 MVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNE 178
Cdd:PHA02876  160 IAEMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIIDNRSNINK 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 179 P-----NAYGNTPLHVACYngqdvvvneLIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTP 253
Cdd:PHA02876  240 NdlsllKAIRNEDLETSLL---------LYDAGFSVNSIDDCKNTPLHHASQAPSLSRLVPKLLERGADVNAKNIKGETP 310

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 254 LHMTALHGRFSRS-QTIIQSGAVIDCEDKNGNTPLHIAA---RYGHELLinTLITSGADTAKRGIHGMFPLHLAALSGFS 329
Cdd:PHA02876  311 LYLMAKNGYDTENiRTLIMLGADVNAADRLYITPLHQAStldRNKDIVI--TLLELGANVNARDYCDKTPIHYAAVRNNV 388

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 330 DCCRKLLSSGFDIDTPDDFGRTCLHAAAAG-GNLECLNLLLNTGADFNKKDKFGRSPLHYAAA-NCNYQCLFALVGSGAS 407
Cdd:PHA02876  389 VIINTLLDYGADIEALSQKIGTALHFALCGtNPYMSVKTLIDRGANVNSKNKDLSTPLHYACKkNCKLDVIEMLLDNGAD 468

                         330
                  ....*....|..
gi 1370483583 408 VNDLDERGCTPL 419
Cdd:PHA02876  469 VNAINIQNQYPL 480

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

233-531

1.54e-30

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 122.37 E-value: 1.54e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 233 LELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKR 312
Cdd:COG0666     4 LLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAK 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 313 GIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAAN 392
Cdd:COG0666    84 DDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAAN 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 393 CNYQCLFALVGSGASVNDLDERGCTPLHYAATSDtDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASET 472
Cdd:COG0666   164 GNLEIVKLLLEAGADVNARDNDGETPLHLAAENG-HLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAG 242

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370483583 473 PLDvlmetsgtdmlsDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPL 531
Cdd:COG0666   243 ADL------------NAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289

ANKYR

Ankyrin repeat [Signal transduction mechanisms];

296-634

5.37e-30

Ankyrin repeat [Signal transduction mechanisms];

Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 120.83 E-value: 5.37e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 296 ELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADF 375
Cdd:COG0666     1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 376 NKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDtDGKCLEYLLRNDANPGIRDKQGYnavhy 455
Cdd:COG0666    81 NAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNG-NLEIVKLLLEAGADVNAQDNDGN----- 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 456 saayghrlclqliasetpldvlmetsgtdmlsdsdnratiSPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAA 535
Cdd:COG0666   155 ----------------------------------------TPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAA 194

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 536 FKGHVECVDVLINQGASILVKDYiLKRTPIHAAATNGHSECLRLLIGNAEpqnAVDIQDGNGQTPLMLSVLNGHTDCVYS 615
Cdd:COG0666   195 ENGHLEIVKLLLEAGADVNAKDN-DGKTALDLAAENGNLEIVKLLLEAGA---DLNAKDKDGLTALLLAAAAGAALIVKL 270

                         330
                  ....*....|....*....
gi 1370483583 616 LLNKGANVDAKDKWGRTAL 634
Cdd:COG0666   271 LLLALLLLAAALLDLLTLL 289

PHA03100

ankyrin repeat protein; Provisional

31-214

1.65e-29

ankyrin repeat protein; Provisional

Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 122.47 E-value: 1.65e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  31 LEAVQVLLKHSADVNARDKNWQTPLHIAAANKavKCAEALVPLL----SNVNVSDRAGRTALHHAAFSGHG--EMVKLLL 104
Cdd:PHA03100   86 KEIVKLLLEYGANVNAPDNNGITPLLYAISKK--SNSYSIVEYLldngANVNIKNSDGENLLHLYLESNKIdlKILKLLI 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 105 SRGANINAfdkKDRraihwaaymghievVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGN 184
Cdd:PHA03100  164 DKGVDINA---KNR--------------VNYLLSYGVPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGD 226

                         170       180       190
                  ....*....|....*....|....*....|
gi 1370483583 185 TPLHVACYNGQDVVVNELIDCGAIVNQKNE 214
Cdd:PHA03100  227 TPLHIAILNNNKEIFKLLLNNGPSIKTIIE 256

PHA02874

ankyrin repeat protein; Provisional

34-311

1.75e-27

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 116.60 E-value: 1.75e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  34 VQVLLKHSADVNARDKNWQTPLHIA---AANKAVK--------CAEALVPLLSNvnvsdragrtalhhaafsghgEMVKL 102
Cdd:PHA02874   51 VELFIKHGADINHINTKIPHPLLTAikiGAHDIIKllidngvdTSILPIPCIEK---------------------DMIKT 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 103 LLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAY 182
Cdd:PHA02874  110 ILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNN 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 183 GNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHfaAASTHGALCLELLVgNGADVNMKSKDGKTPLHMtALHGR 262
Cdd:PHA02874  190 GESPLHNAAEYGDYACIKLLIDHGNHIMNKCKNGFTPLH--NAIIHNRSAIELLI-NNASINDQDIDGSTPLHH-AINPP 265

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370483583 263 FSRS--QTIIQSGAVIDCEDKNGNTPLHIAARYGH------ELLINTLITSGADTAK 311
Cdd:PHA02874  266 CDIDiiDILLYHKADISIKDNKGENPIDTAFKYINkdpvikDIIANAVLIKEADKLK 322

PHA02874

ankyrin repeat protein; Provisional

93-463

1.02e-26

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 114.29 E-value: 1.02e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  93 FSGHGEMV-KLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLD 171
Cdd:PHA02874   10 YSGDIEAIeKIIKNKGNCINISVDETTTPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLID 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 172 LGVDmnepnaygNTPLHVACYNGQdvVVNELIDCGAIVNQKNEKGFTPLHFAAASthGAL-CLELLVGNGADVNMKSKDG 250
Cdd:PHA02874   90 NGVD--------TSILPIPCIEKD--MIKTILDCGIDVNIKDAELKTFLHYAIKK--GDLeSIKMLFEYGADVNIEDDNG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 251 KTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALsgfsd 330
Cdd:PHA02874  158 CYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNAII----- 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 331 ccrkllssgfdidtpddfgrtclhaaaaggnleclnlllntgadfnkkdkFGRSPLhyaaancnyqclfALVGSGASVND 410
Cdd:PHA02874  233 --------------------------------------------------HNRSAI-------------ELLINNASIND 249

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1370483583 411 LDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRL 463
Cdd:PHA02874  250 QDIDGSTPLHHAINPPCDIDIIDILLYHKADISIKDNKGENPIDTAFKYINKD 302

PHA02874

ankyrin repeat protein; Provisional

77-323

4.11e-26

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 112.75 E-value: 4.11e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  77 VNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAE-------------- 142
Cdd:PHA02874   28 INISVDETTTPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLIDNGVDtsilpipciekdmi 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 143 ---------VTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKN 213
Cdd:PHA02874  108 ktildcgidVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKD 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 214 EKGFTPLHFAAASTHGAlCLELLVGNGADVNMKSKDGKTPLHMTALHGRfSRSQTIIQSgAVIDCEDKNGNTPLHIAARY 293
Cdd:PHA02874  188 NNGESPLHNAAEYGDYA-CIKLLIDHGNHIMNKCKNGFTPLHNAIIHNR-SAIELLINN-ASINDQDIDGSTPLHHAINP 264

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1370483583 294 GHEL-LINTLITSGADTAKRGIHGMFPLHLA 323
Cdd:PHA02874  265 PCDIdIIDILLYHKADISIKDNKGENPIDTA 295

PHA03100

ankyrin repeat protein; Provisional

130-344

7.90e-25

ankyrin repeat protein; Provisional

Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 108.60 E-value: 7.90e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 130 IEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLH---VACYNGQDVV--VNELID 204
Cdd:PHA03100   15 VKNIKYIIMEDDLNDYSYKKPVLPLYLAKEARNIDVVKILLDNGADINSSTKNNSTPLHylsNIKYNLTDVKeiVKLLLE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 205 CGAIVNQKNEKGFTPLHFAAASTHGALCL-ELLVGNGADVNMKSKDGKTPLHMtAL---HGRFSRSQTIIQSGA------ 274
Cdd:PHA03100   95 YGANVNAPDNNGITPLLYAISKKSNSYSIvEYLLDNGANVNIKNSDGENLLHL-YLesnKIDLKILKLLIDKGVdinakn 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 275 ----------VIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDT 344
Cdd:PHA03100  174 rvnyllsygvPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLLLNNGPSIKT 253

PHA02876

ankyrin repeat protein; Provisional

34-308

2.02e-24

ankyrin repeat protein; Provisional

Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 109.77 E-value: 2.02e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  34 VQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRA-----------------------------G 84
Cdd:PHA02876  194 VNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIIDNRSNINKNDLSllkairnedletslllydagfsvnsiddcK 273

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  85 RTALHHAAFSGH-GEMVKLLLSRGANINAFDKKDRRAIHWAAYMGH-IEVVKLLVSHGAEVTCKDKKSYTPLHAAAS-SG 161
Cdd:PHA02876  274 NTPLHHASQAPSlSRLVPKLLERGADVNAKNIKGETPLYLMAKNGYdTENIRTLIMLGADVNAADRLYITPLHQASTlDR 353

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 162 MISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGA 241
Cdd:PHA02876  354 NKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFALCGTNPYMSVKTLIDRGA 433

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370483583 242 DVNMKSKDGKTPLHMTALHG-RFSRSQTIIQSGAVIDCEDKNGNTPLHIAarYGHELLINTLITSGAD 308
Cdd:PHA02876  434 NVNSKNKDLSTPLHYACKKNcKLDVIEMLLDNGADVNAINIQNQYPLLIA--LEYHGIVNILLHYGAE 499

PHA02874

ankyrin repeat protein; Provisional

498-807

7.99e-23

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 102.73 E-value: 7.99e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 498 LHLAAYHGHHQALEVLVQS---LLDLDVRNSSgrTPLDLAAFKGHVECVDVLINQGASIlvkDYILKRTP--IHAAATNG 572
Cdd:PHA02874    5 LRMCIYSGDIEAIEKIIKNkgnCINISVDETT--TPLIDAIRSGDAKIVELFIKHGADI---NHINTKIPhpLLTAIKIG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 573 HSECLRLLIgnaepQNAVDIQdgngqtplMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQH 652
Cdd:PHA02874   80 AHDIIKLLI-----DNGVDTS--------ILPIPCIEKDMIKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEY 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 653 GAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDANpataDNHGYTALHWACYNGHETCVELLLEQ--EVFQKTEg 730
Cdd:PHA02874  147 GADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVK----DNNGESPLHNAAEYGDYACIKLLIDHgnHIMNKCK- 221

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370483583 731 NAFSPLHCAVINdNEGAAEMLIDTlgASIvNATDSKGRTPLH-AAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMA 807
Cdd:PHA02874  222 NGFTPLHNAIIH-NRSAIELLINN--ASI-NDQDIDGSTPLHhAINPPCDIDIIDILLYHKADISIKDNKGENPIDTA 295

PHA02878

ankyrin repeat protein; Provisional

31-297

1.02e-22

ankyrin repeat protein; Provisional

Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 103.04 E-value: 1.02e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  31 LEAVQVLLKHSADVNARDKNWQTPLHIA--AANKavkcaEALVPLLSNVNVSD-----RAGRTALHHAAFsghgEMVK-L 102
Cdd:PHA02878   50 LDVVKSLLTRGHNVNQPDHRDLTPLHIIckEPNK-----LGMKEMIRSINKCSvfytlVAIKDAFNNRNV----EIFKiI 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 103 LLSRGANINAFDKKDRRAIHWAAYMgHIEVVKLLVSHGAEVTCKDK-KSYTPLHAAASSGMISVVKYLLDLGVDMNEPNA 181
Cdd:PHA02878  121 LTNRYKNIQTIDLVYIDKKSKDDII-EAEITKLLLSYGADINMKDRhKGNTALHYATENKDQRLTELLLSYGANVNIPDK 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 182 YGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSK-DGKTPLHMtALH 260
Cdd:PHA02878  200 TNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISVGYCKDYDILKLLLEHGVDVNAKSYiLGLTALHS-SIK 278

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1370483583 261 GRfSRSQTIIQSGAVIDCEDKNGNTPLHIAA--RYGHEL 297
Cdd:PHA02878  279 SE-RKLKLLLEYGADINSLNSYKLTPLSSAVkqYLCINI 316

Ank_2

Ankyrin repeats (3 copies);

88-180

5.35e-21

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 88.25 E-value: 5.35e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  88 LHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHgAEVTCKDKKsYTPLHAAASSGMISVVK 167
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDNG-RTALHYAARSGHLEIVK 78

                          90
                  ....*....|...
gi 1370483583 168 YLLDLGVDMNEPN 180
Cdd:pfam12796  79 LLLEKGADINVKD 91

Ank_2

Ankyrin repeats (3 copies);

55-147

7.38e-21

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 87.86 E-value: 7.38e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  55 LHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRgANINAFDkKDRRAIHWAAYMGHIEVVK 134
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKD-NGRTALHYAARSGHLEIVK 78

                          90
                  ....*....|...
gi 1370483583 135 LLVSHGAEVTCKD 147
Cdd:pfam12796  79 LLLEKGADINVKD 91

Ank_2

Ankyrin repeats (3 copies);

121-213

7.62e-20

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 85.17 E-value: 7.62e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 121 IHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDlGVDMNEPNaYGNTPLHVACYNGQDVVVN 200
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLE-HADVNLKD-NGRTALHYAARSGHLEIVK 78

                          90
                  ....*....|...
gi 1370483583 201 ELIDCGAIVNQKN 213
Cdd:pfam12796  79 LLLEKGADINVKD 91

PHA03095

ankyrin-like protein; Provisional

597-926

2.41e-19

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 92.40 E-value: 2.41e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 597 GQTPLMLSVLNGHTDC---VYSLLNKGANVDAKDKWGRTALH---RGAVTghEECVDALLQHGAKCLLRDSRGRTPIH-- 668
Cdd:PHA03095   47 GKTPLHLYLHYSSEKVkdiVRLLLEAGADVNAPERCGFTPLHlylYNATT--LDVIKLLIKAGADVNAKDKVGRTPLHvy 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 669 LSAACGHIGVLGALLQsaasMDANPATADNHGYTalhwacynghetcvellleqevfqktegnafsPLHCAVINdnegaa 748
Cdd:PHA03095  125 LSGFNINPKVIRLLLR----KGADVNALDLYGMT--------------------------------PLAVLLKS------ 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 749 emlidtlgasiVNATdskgrtplhaaaftdhVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNT--VEMLVSsASAE 826
Cdd:PHA03095  163 -----------RNAN----------------VELLRLLIDAGADVYAVDDRFRSLLHHHLQSFKPRAriVRELIR-AGCD 214

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 827 LTLQDNSKNTALHLACSKGHETSALLI--LEKITDrnlINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGY 904
Cdd:PHA03095  215 PAATDMLGNTPLHSMATGSSCKRSLVLplLIAGIS---INARNRYGQTPLHYAAVFNNPRACRRLIALGADINAVSSDGN 291

                         330       340
                  ....*....|....*....|..
gi 1370483583 905 TPALACAPNKDVaDCLALILAT 926
Cdd:PHA03095  292 TPLSLMVRNNNG-RAVRAALAK 312

Ank_2

Ankyrin repeats (3 copies);

30-114

1.65e-18

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 81.32 E-value: 1.65e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  30 YLEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLsNVNVSDRaGRTALHHAAFSGHGEMVKLLLSRGAN 109
Cdd:pfam12796   9 NLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHA-DVNLKDN-GRTALHYAARSGHLEIVKLLLEKGAD 86


                  ....*
gi 1370483583 110 INAFD 114
Cdd:pfam12796  87 INVKD 91

Ank_2

Ankyrin repeats (3 copies);

565-660

1.75e-18

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 81.32 E-value: 1.75e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 565 IHAAATNGHSECLRLLIgnaEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKgANVDAKDKwGRTALHRGAVTGHEE 644
Cdd:pfam12796   1 LHLAAKNGNLELVKLLL---ENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDN-GRTALHYAARSGHLE 75

                          90
                  ....*....|....*.
gi 1370483583 645 CVDALLQHGAKCLLRD 660
Cdd:pfam12796  76 IVKLLLEKGADINVKD 91

Ank_2

Ankyrin repeats (3 copies);

531-627

2.30e-18

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 80.93 E-value: 2.30e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 531 LDLAAFKGHVECVDVLINQGASILVKDyILKRTPIHAAATNGHSECLRLLIGNAEPQNavdiqDGNGQTPLMLSVLNGHT 610
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQD-KNGRTALHLAAKNGHLEIVKLLLEHADVNL-----KDNGRTALHYAARSGHL 74

                          90
                  ....*....|....*..
gi 1370483583 611 DCVYSLLNKGANVDAKD 627
Cdd:pfam12796  75 EIVKLLLEKGADINVKD 91

PHA03095

ankyrin-like protein; Provisional

519-799

2.95e-18

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 88.93 E-value: 2.95e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 519 DLDVRNSSGRTPLDLAAFKGHVECVDV---LINQGASILVKDyILKRTPIHAAATNGHSE-CLRLLIGNaepqNA-VDIQ 593
Cdd:PHA03095   39 DVNFRGEYGKTPLHLYLHYSSEKVKDIvrlLLEAGADVNAPE-RCGFTPLHLYLYNATTLdVIKLLIKA----GAdVNAK 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 594 DGNGQTPL--MLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALH----RGAVTghEECVDALLQHGAKCLLRDSRGRTPI 667
Cdd:PHA03095  114 DKVGRTPLhvYLSGFNINPKVIRLLLRKGADVNALDLYGMTPLAvllkSRNAN--VELLRLLIDAGADVYAVDDRFRSLL 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 668 HLSAACGHI--GVLGALLQSAAsmdaNPATADNHGYTALHWACYngHETCVELLLEQEVFQKTEGNA-----FSPLHCAV 740
Cdd:PHA03095  192 HHHLQSFKPraRIVRELIRAGC----DPAATDMLGNTPLHSMAT--GSSCKRSLVLPLLIAGISINArnrygQTPLHYAA 265

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370483583 741 INDNEGAAEMLIdTLGASIvNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDST 799
Cdd:PHA03095  266 VFNNPRACRRLI-ALGADI-NAVSSDGNTPLSLMVRNNNGRAVRAALAKNPSAETVAAT 322

Ank_2

Ankyrin repeats (3 copies);

154-246

5.90e-18

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 79.77 E-value: 5.90e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 154 LHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIvnQKNEKGFTPLHFAAASTHGAlCL 233
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADV--NLKDNGRTALHYAARSGHLE-IV 77

                          90
                  ....*....|...
gi 1370483583 234 ELLVGNGADVNMK 246
Cdd:pfam12796  78 KLLLEKGADINVK 90

PHA02876

ankyrin repeat protein; Provisional

372-721

7.97e-18

ankyrin repeat protein; Provisional

Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 88.58 E-value: 7.97e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 372 GADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDtDGKCLEYLLRNDANPGIRDKQGYN 451
Cdd:PHA02876  168 GADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSK-NIDTIKAIIDNRSNINKNDLSLLK 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 452 AVHYSAAyghrlclqliasETPLdvLMETSGTDMLSDSDNRATisPLHLAAyhgHHQALEVLVQSLL----DLDVRNSSG 527
Cdd:PHA02876  247 AIRNEDL------------ETSL--LLYDAGFSVNSIDDCKNT--PLHHAS---QAPSLSRLVPKLLergaDVNAKNIKG 307

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 528 RTPLDLAAFKGH-VECVDVLINQGASILVKDYiLKRTPIHAAATnghseclrllignaepqnavdiqdgngqtplmlsvL 606
Cdd:PHA02876  308 ETPLYLMAKNGYdTENIRTLIMLGADVNAADR-LYITPLHQAST-----------------------------------L 351

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 607 NGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLsAACGHIGVLGalLQSA 686
Cdd:PHA02876  352 DRNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHF-ALCGTNPYMS--VKTL 428

                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 1370483583 687 ASMDANPATADNHGYTALHWACYNGHE-TCVELLLE 721
Cdd:PHA02876  429 IDRGANVNSKNKDLSTPLHYACKKNCKlDVIEMLLD 464

PHA02878

ankyrin repeat protein; Provisional

32-261

1.08e-17

ankyrin repeat protein; Provisional

Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 87.24 E-value: 1.08e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  32 EAVQVLLKHSADVNARDKNW-QTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANI 110
Cdd:PHA02878  148 EITKLLLSYGADINMKDRHKgNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGAST 227

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 111 NAFDKKDRRAIHWA-AYMGHIEVVKLLVSHGAEVTCKdkksytplhaaassgmisvvKYLLDLgvdmnepnaygnTPLHV 189
Cdd:PHA02878  228 DARDKCGNTPLHISvGYCKDYDILKLLLEHGVDVNAK--------------------SYILGL------------TALHS 275

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370483583 190 ACYNGQdvVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPL----HMTALHG 261
Cdd:PHA02878  276 SIKSER--KLKLLLEYGADINSLNSYKLTPLSSAVKQYLCINIGRILISNICLLKRIKPDIKNSEgfidNMDCITS 349

PHA03095

ankyrin-like protein; Provisional

333-701

2.34e-17

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 86.23 E-value: 2.34e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 333 RKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECL---NLLLNTGADFNKKDKFGRSPLH-YAAANCNYQCLFALVGSGASV 408
Cdd:PHA03095   31 RRLLAAGADVNFRGEYGKTPLHLYLHYSSEKVKdivRLLLEAGADVNAPERCGFTPLHlYLYNATTLDVIKLLIKAGADV 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 409 NDLDERGCTPLH-YAATSDTDGKCLEYLLRNDANPGIRDKqgynavhysaaYGHrlclqliaseTPLDVLMetsgtdmls 487
Cdd:PHA03095  111 NAKDKVGRTPLHvYLSGFNINPKVIRLLLRKGADVNALDL-----------YGM----------TPLAVLL--------- 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 488 dSDNRATISPLHLaayhghhqalevLVQSLLDLDVRNSSGRTPLD--LAAFKGHVECVDVLINQGASILVKDyILKRTPI 565
Cdd:PHA03095  161 -KSRNANVELLRL------------LIDAGADVYAVDDRFRSLLHhhLQSFKPRARIVRELIRAGCDPAATD-MLGNTPL 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 566 HAAATngHSECLRLLIGNaepqnavdiqdgngqtplmlsvlnghtdcvysLLNKGANVDAKDKWGRTALHRGAVTGHEEC 645
Cdd:PHA03095  227 HSMAT--GSSCKRSLVLP--------------------------------LLIAGISINARNRYGQTPLHYAAVFNNPRA 272

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370483583 646 VDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQ---SAASMDANPATADNHGY 701
Cdd:PHA03095  273 CRRLIALGADINAVSSDGNTPLSLMVRNNNGRAVRAALAknpSAETVAATLNTASVAGG 331

PHA02874

ankyrin repeat protein; Provisional

32-223

6.45e-17

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 84.63 E-value: 6.45e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  32 EAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANIN 111
Cdd:PHA02874  105 DMIKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYAN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 112 AFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMiSVVKYLLDlGVDMNEPNAYGNTPLHVAC 191
Cdd:PHA02874  185 VKDNNGESPLHNAAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNAIIHNR-SAIELLIN-NASINDQDIDGSTPLHHAI 262

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1370483583 192 YNGQDV-VVNELIDCGAIVNQKNEKGFTPLHFA 223
Cdd:PHA02874  263 NPPCDIdIIDILLYHKADISIKDNKGENPIDTA 295

PHA02875

ankyrin repeat protein; Provisional

32-210

1.22e-16

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 83.50 E-value: 1.22e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  32 EAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALvpLLSNVNVSD---RAGRTALHHAAFSGHGEMVKLLLSRGA 108
Cdd:PHA02875   49 EAIKLLMKHGAIPDVKYPDIESELHDAVEEGDVKAVEEL--LDLGKFADDvfyKDGMTPLHLATILKKLDIMKLLIARGA 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 109 NINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDmnePNAYGNTP-L 187
Cdd:PHA02875  127 DPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGAN---IDYFGKNGcV 203

                         170       180
                  ....*....|....*....|....*.
gi 1370483583 188 HVACY---NGQDVVVNELIDCGAIVN 210
Cdd:PHA02875  204 AALCYaieNNKIDIVRLFIKRGADCN 229

Ank_2

Ankyrin repeats (3 copies);

771-864

1.30e-16

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 75.92 E-value: 1.30e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 771 LHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELtlqDNSKNTALHLACSKGHETSA 850
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVNL---KDNGRTALHYAARSGHLEIV 77

                          90
                  ....*....|....
gi 1370483583 851 LLILEKITDRNLIN 864
Cdd:pfam12796  78 KLLLEKGADINVKD 91

Ank_2

Ankyrin repeats (3 copies);

601-692

5.62e-16

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 74.00 E-value: 5.62e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 601 LMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAkcLLRDSRGRTPIHLSAACGHIGVLG 680
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHAD--VNLKDNGRTALHYAARSGHLEIVK 78

                          90
                  ....*....|..
gi 1370483583 681 ALLQSAASMDAN 692
Cdd:pfam12796  79 LLLEKGADINVK 90

PLN03192

Voltage-dependent potassium channel; Provisional

475-654

1.17e-15

Voltage-dependent potassium channel; Provisional

Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 81.84 E-value: 1.17e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 475 DVLMETSGTDmlsdsDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASIL 554
Cdd:PLN03192  511 DLLGDNGGEH-----DDPNMASNLLTVASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVH 585

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 555 VKDyILKRTPIHAAATNGHSECLRLLIGNA---EPQNAVDIqdgngqtpLMLSVLNGHTDCVYSLLNKGANVDAKDKWGR 631
Cdd:PLN03192  586 IRD-ANGNTALWNAISAKHHKIFRILYHFAsisDPHAAGDL--------LCTAAKRNDLTAMKELLKQGLNVDSEDHQGA 656

                         170       180
                  ....*....|....*....|...
gi 1370483583 632 TALHRGAVTGHEECVDALLQHGA 654
Cdd:PLN03192  657 TALQVAMAEDHVDMVRLLIMNGA 679

PHA02874

ankyrin repeat protein; Provisional

6-211

1.28e-15

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 80.39 E-value: 1.28e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583   6 TMKSEPHCTPQLTLEMQKSLNFLFY------LEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNV 79
Cdd:PHA02874  106 MIKTILDCGIDVNIKDAELKTFLHYaikkgdLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANV 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  80 SDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHwAAYMGHIEVVKLLVSHgAEVTCKDKKSYTPLHAAAS 159
Cdd:PHA02874  186 KDNNGESPLHNAAEYGDYACIKLLIDHGNHIMNKCKNGFTPLH-NAIIHNRSAIELLINN-ASINDQDIDGSTPLHHAIN 263

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1370483583 160 SGM-ISVVKYLLDLGVDMNEPNAYGNTPLHVAC-YNGQDVVVNELIDCGAIVNQ 211
Cdd:PHA02874  264 PPCdIDIIDILLYHKADISIKDNKGENPIDTAFkYINKDPVIKDIIANAVLIKE 317

Ank_2

Ankyrin repeats (3 copies);

704-797

2.13e-15

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 72.46 E-value: 2.13e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 704 LHWACYNGHETCVELLLEQEV-FQKTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNatdsKGRTPLHAAAFTDHVEC 782
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGAdANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVNLKD----NGRTALHYAARSGHLEI 76

                          90
                  ....*....|....*
gi 1370483583 783 LQLLLSHNAQVNSVD 797
Cdd:pfam12796  77 VKLLLEKGADINVKD 91

PHA02878

ankyrin repeat protein; Provisional

153-467

3.81e-15

ankyrin repeat protein; Provisional

Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 79.15 E-value: 3.81e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 153 PLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIdcgAIVNQ--------------------- 211
Cdd:PHA02878   40 PLHQAVEARNLDVVKSLLTRGHNVNQPDHRDLTPLHIICKEPNKLGMKEMI---RSINKcsvfytlvaikdafnnrnvei 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 212 ---------KNEKGFTPLHFAAASTHGAL---CLELLVGNGADVNMKSKD-GKTPLHMTALHGRFSRSQTIIQSGAVIDC 278
Cdd:PHA02878  117 fkiiltnryKNIQTIDLVYIDKKSKDDIIeaeITKLLLSYGADINMKDRHkGNTALHYATENKDQRLTELLLSYGANVNI 196

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 279 EDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFS-DCCRKLLSSGFDIDTpddfgrtclhaaa 357
Cdd:PHA02878  197 PDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISVGYCKDyDILKLLLEHGVDVNA------------- 263

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 358 aggnleclnlllntgadfnKKDKFGRSPLHYAAAncNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYL-- 435
Cdd:PHA02878  264 -------------------KSYILGLTALHSSIK--SERKLKLLLEYGADINSLNSYKLTPLSSAVKQYLCINIGRILis 322

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 1370483583 436 ---LRNDANPGIRDKQGYnAVHYSAAYGHRLCLQL 467
Cdd:PHA02878  323 nicLLKRIKPDIKNSEGF-IDNMDCITSNKRLNQI 356

PHA02876

ankyrin repeat protein; Provisional

616-908

5.48e-15

ankyrin repeat protein; Provisional

Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 79.34 E-value: 5.48e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 616 LLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDANPAT 695
Cdd:PHA02876  164 LLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIIDNRSNINKNDLS 243

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 696 -------------------------ADNHGYTALHWACYNGH-ETCVELLLEQEVFQKTEG-NAFSPLHCAVINDNEGAA 748
Cdd:PHA02876  244 llkairnedletslllydagfsvnsIDDCKNTPLHHASQAPSlSRLVPKLLERGADVNAKNiKGETPLYLMAKNGYDTEN 323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 749 EMLIDTLGASiVNATDSKGRTPLHAAAFTD-HVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSAsAEL 827
Cdd:PHA02876  324 IRTLIMLGAD-VNAADRLYITPLHQASTLDrNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYG-ADI 401

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 828 TLQDNSKNTALHLACskgHETSALLILEKITDRNL-INATNAALQTPLHVAARNGLTM-VVQELLGKGASVLAVDENGYT 905
Cdd:PHA02876  402 EALSQKIGTALHFAL---CGTNPYMSVKTLIDRGAnVNSKNKDLSTPLHYACKKNCKLdVIEMLLDNGADVNAINIQNQY 478


                  ...
gi 1370483583 906 PAL 908
Cdd:PHA02876  479 PLL 481

PHA03100

ankyrin repeat protein; Provisional

716-902

5.86e-15

ankyrin repeat protein; Provisional

Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 78.17 E-value: 5.86e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 716 VELLLEQ--EVFQKTEGNaFSPLH-----CAVINDNEGAAEMLIDtLGASIvNATDSKGRTPLHAAAFT--DHVECLQLL 786
Cdd:PHA03100   51 VKILLDNgaDINSSTKNN-STPLHylsniKYNLTDVKEIVKLLLE-YGANV-NAPDNNGITPLLYAISKksNSYSIVEYL 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 787 LSHNAQVNSVDSTGKTPLMMAAENG------------------QTNTVEMLVSSASaELTLQDNSKNTALHLACSKGHET 848
Cdd:PHA03100  128 LDNGANVNIKNSDGENLLHLYLESNkidlkilkllidkgvdinAKNRVNYLLSYGV-PINIKDVYGFTPLHYAVYNNNPE 206

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1370483583 849 SALLILEKITDRNLINATNaalQTPLHVAARNGLTMVVQELLGKGASVLAVDEN 902
Cdd:PHA03100  207 FVKYLLDLGANPNLVNKYG---DTPLHIAILNNNKEIFKLLLNNGPSIKTIIET 257

PHA02874

ankyrin repeat protein; Provisional

254-591

9.29e-15

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 77.70 E-value: 9.29e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 254 LHMTALHGRFSRSQTIIQS-GAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCC 332
Cdd:PHA02874    5 LRMCIYSGDIEAIEKIIKNkGNCINISVDETTTPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDII 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 333 RKLLSSGFDI------DTPDDFGRTCLHaaaaggnleclnlllnTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGA 406
Cdd:PHA02874   85 KLLIDNGVDTsilpipCIEKDMIKTILD----------------CGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGA 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 407 SVNDLDERGCTPLHYAATSDTdGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIAsetpldvlmeTSGTDML 486
Cdd:PHA02874  149 DVNIEDDNGCYPIHIAIKHNF-FDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACIKLLI----------DHGNHIM 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 487 SDSDNRATisPLHLAAYHgHHQALEVLVQSlLDLDVRNSSGRTPLDLA-AFKGHVECVDVLINQGASILVKDYiLKRTPI 565
Cdd:PHA02874  218 NKCKNGFT--PLHNAIIH-NRSAIELLINN-ASINDQDIDGSTPLHHAiNPPCDIDIIDILLYHKADISIKDN-KGENPI 292

                         330       340
                  ....*....|....*....|....*..
gi 1370483583 566 HAAATN-GHSECLRLLIGNAEPQNAVD 591
Cdd:PHA02874  293 DTAFKYiNKDPVIKDIIANAVLIKEAD 319

PHA02876

ankyrin repeat protein; Provisional

136-662

1.05e-14

ankyrin repeat protein; Provisional

Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 78.57 E-value: 1.05e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 136 LVSHGAEvTCKDKK-SYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYG-NTPLHVACY--NGQDVVVNELIDCGAIVNQ 211
Cdd:PHA02876   27 LHKHGAN-QCENESiPFTAIHQALQLRQIDIVEEIIQQNPELIYITDHKcHSTLHTICIipNVMDIVISLTLDCDIILDI 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 212 KNEKGFTPLHfaaasTHGALCLELLVG--NGADVNMkSKDGKTPLHMTALHGRFSRSQTIIQSgavidcedkngntplhi 289
Cdd:PHA02876  106 KYASIILNKH-----KLDEACIHILKEaiSGNDIHY-DKINESIEYMKLIKERIQQDELLIAE----------------- 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 290 aaryghellinTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLL 369
Cdd:PHA02876  163 -----------MLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAII 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 370 NTGADFNKKDkfgrSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQG 449
Cdd:PHA02876  232 DNRSNINKND----LSLLKAIRNEDLETSLLLYDAGFSVNSIDDCKNTPLHHASQAPSLSRLVPKLLERGADVNAKNIKG 307

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 450 YNAVHYSAAYGHRlclqliaSETPLDVLMEtsGTDMlsDSDNRATISPLHLAAYHGHHQALEVLVQSL-LDLDVRNSSGR 528
Cdd:PHA02876  308 ETPLYLMAKNGYD-------TENIRTLIML--GADV--NAADRLYITPLHQASTLDRNKDIVITLLELgANVNARDYCDK 376

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 529 TPLDLAAFKGHVECVDVLINQGASILVKDYILKrTPIHAA--ATNGHSECLRLLIGNAEpqnaVDIQDGNGQTPLMLSVL 606
Cdd:PHA02876  377 TPIHYAAVRNNVVIINTLLDYGADIEALSQKIG-TALHFAlcGTNPYMSVKTLIDRGAN----VNSKNKDLSTPLHYACK 451

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370483583 607 NG-HTDCVYSLLNKGANVDAKDKWGRTALHrgAVTGHEECVDALLQHGAKclLRDSR 662
Cdd:PHA02876  452 KNcKLDVIEMLLDNGADVNAINIQNQYPLL--IALEYHGIVNILLHYGAE--LRDSR 504

PHA03100

ankyrin repeat protein; Provisional

371-628

1.31e-14

ankyrin repeat protein; Provisional

Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 77.40 E-value: 1.31e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 371 TGADFNKKDKFGRSPLHYAA-----ANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSD-TDGKCLEYLLRNDANPGI 444
Cdd:PHA03100   57 NGADINSSTKNNSTPLHYLSnikynLTDVKEIVKLLLEYGANVNAPDNNGITPLLYAISKKsNSYSIVEYLLDNGANVNI 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 445 RDKQGYNAVHYSAAYGHRlclqliasETPLDVLMETSGTDMlsDSDNRatisplhlaayhghhqaLEVLVQSLLDLDVRN 524
Cdd:PHA03100  137 KNSDGENLLHLYLESNKI--------DLKILKLLIDKGVDI--NAKNR-----------------VNYLLSYGVPINIKD 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 525 SSGRTPLDLAAFKGHVECVDVLINQGASIlvkdyilkrtpihaaatnghseclrllignaepqNAVDIqdgNGQTPLMLS 604
Cdd:PHA03100  190 VYGFTPLHYAVYNNNPEFVKYLLDLGANP----------------------------------NLVNK---YGDTPLHIA 232

                         250       260
                  ....*....|....*....|....
gi 1370483583 605 VLNGHTDCVYSLLNKGANVDAKDK 628
Cdd:PHA03100  233 ILNNNKEIFKLLLNNGPSIKTIIE 256

PHA02798

ankyrin-like protein; Provisional

31-308

1.27e-13

ankyrin-like protein; Provisional

Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 74.49 E-value: 1.27e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  31 LEAVQVLLKHSADVNARDKNWQTPLhiaaankavkCAealvpLLSNVnvsdRAGRTALhhaafsghgEMVKLLLSRGANI 110
Cdd:PHA02798   51 TDIVKLFINLGANVNGLDNEYSTPL----------CT-----ILSNI----KDYKHML---------DIVKILIENGADI 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 111 NAFDKKDRRAIHWA---AYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGM---ISVVKYLLDLGVDMNE-PNAYG 183
Cdd:PHA02798  103 NKKNSDGETPLYCLlsnGYINNLEILLFMIENGADTTLLDKDGFTMLQVYLQSNHhidIEIIKLLLEKGVDINThNNKEK 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 184 NTPLHvaCYNGQDV------VVNELIDCGAIVNQKNEkgftplhfAAASTHGALCLELLVGNGA-------------DVN 244
Cdd:PHA02798  183 YDTLH--CYFKYNIdridadILKLFVDNGFIINKENK--------SHKKKFMEYLNSLLYDNKRfkknildfifsyiDIN 252

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370483583 245 MKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGAD 308
Cdd:PHA02798  253 QVDELGFNPLYYSVSHNNRKIFEYLLQLGGDINIITELGNTCLFTAFENESKFIFNSILNKKPN 316

PHA03100

ankyrin repeat protein; Provisional

556-823

3.19e-13

ankyrin repeat protein; Provisional

Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 72.78 E-value: 3.19e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 556 KDYILKRTPIHAAATNGHseclrllignaepqnAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALH 635
Cdd:PHA03100    9 KSRIIKVKNIKYIIMEDD---------------LNDYSYKKPVLPLYLAKEARNIDVVKILLDNGADINSSTKNNSTPLH 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 636 RGAVTGHE-----ECVDALLQHGAKCLLRDSRGRTPIHLSAAC--GHIGVLGALLQSAAsmDANPATADnhGYTALHWA- 707
Cdd:PHA03100   74 YLSNIKYNltdvkEIVKLLLEYGANVNAPDNNGITPLLYAISKksNSYSIVEYLLDNGA--NVNIKNSD--GENLLHLYl 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 708 --CYNGHETcVELLLEqevfqktegnafsplHCAVINdNEGAAEMLIdTLGASIvNATDSKGRTPLHAAAFTDHVECLQL 785
Cdd:PHA03100  150 esNKIDLKI-LKLLID---------------KGVDIN-AKNRVNYLL-SYGVPI-NIKDVYGFTPLHYAVYNNNPEFVKY 210

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1370483583 786 LLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSA 823
Cdd:PHA03100  211 LLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLLLNNG 248

Ank_2

Ankyrin repeats (3 copies);

804-900

5.89e-13

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 65.52 E-value: 5.89e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 804 LMMAAENGQTNTVEMLVSSaSAELTLQDNSKNTALHLACSKGHETSALLILEKItDRNLINATNaalqTPLHVAARNGLT 883
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLEN-GADANLQDKNGRTALHLAAKNGHLEIVKLLLEHA-DVNLKDNGR----TALHYAARSGHL 74

                          90
                  ....*....|....*..
gi 1370483583 884 MVVQELLGKGASVLAVD 900
Cdd:pfam12796  75 EIVKLLLEKGADINVKD 91

PHA02875

ankyrin repeat protein; Provisional

157-341

6.72e-13

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 71.95 E-value: 6.72e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 157 AASSGMISVVKYLLDLGVDMN--------------------------EPNAYGN-------TPLHVACYNGQDVVVNELI 203
Cdd:PHA02875    9 AILFGELDIARRLLDIGINPNfeiydgispiklamkfrdseaikllmKHGAIPDvkypdieSELHDAVEEGDVKAVEELL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 204 DCGAIVNQK-NEKGFTPLHFAAASTHGALcLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKN 282
Cdd:PHA02875   89 DLGKFADDVfYKDGMTPLHLATILKKLDI-MKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCC 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 283 GNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFS-DCCRKLLSSGFD 341
Cdd:PHA02875  168 GCTPLIIAMAKGDIAICKMLLDSGANIDYFGKNGCVAALCYAIENNKiDIVRLFIKRGAD 227

Ank_2

Ankyrin repeats (3 copies);

254-346

7.74e-13

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 65.14 E-value: 7.74e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 254 LHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGAdtAKRGIHGMFPLHLAALSGFSDCCR 333
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHAD--VNLKDNGRTALHYAARSGHLEIVK 78

                          90
                  ....*....|...
gi 1370483583 334 KLLSSGFDIDTPD 346
Cdd:pfam12796  79 LLLEKGADINVKD 91

PHA02876

ankyrin repeat protein; Provisional

647-901

8.19e-13

ankyrin repeat protein; Provisional

Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 72.40 E-value: 8.19e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 647 DALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAAsmDANPATADnhGYTALHWACYNGHETCVELLLEQEvfQ 726
Cdd:PHA02876  162 EMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGA--DVNIIALD--DLSVLECAVDSKNIDTIKAIIDNR--S 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 727 KTEGNAFSPLHcAVINDNEGAAEMLIDTlGASiVNATDSKGRTPLHAAAFTDHVECL-QLLLSHNAQVNSVDSTGKTPLM 805
Cdd:PHA02876  236 NINKNDLSLLK-AIRNEDLETSLLLYDA-GFS-VNSIDDCKNTPLHHASQAPSLSRLvPKLLERGADVNAKNIKGETPLY 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 806 MAAENG-QTNTVEMLVSSAsAELTLQDNSKNTALHLACSKGHETSALLILEKITDRnlINATNAALQTPLHVAARNGLTM 884
Cdd:PHA02876  313 LMAKNGyDTENIRTLIMLG-ADVNAADRLYITPLHQASTLDRNKDIVITLLELGAN--VNARDYCDKTPIHYAAVRNNVV 389

                         250
                  ....*....|....*..
gi 1370483583 885 VVQELLGKGASVLAVDE 901
Cdd:PHA02876  390 IINTLLDYGADIEALSQ 406

PHA02874

ankyrin repeat protein; Provisional

481-667

8.38e-13

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 71.53 E-value: 8.38e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 481 SGTDMlsDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYIL 560
Cdd:PHA02874  113 CGIDV--NIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNG 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 561 KrTPIHAAATNGHSECLRLLIGNAepqNAVDIQDGNGQTPLMLSVLngHTDCVYSLLNKGANVDAKDKWGRTALHRG-AV 639
Cdd:PHA02874  191 E-SPLHNAAEYGDYACIKLLIDHG---NHIMNKCKNGFTPLHNAII--HNRSAIELLINNASINDQDIDGSTPLHHAiNP 264

                         170       180
                  ....*....|....*....|....*...
gi 1370483583 640 TGHEECVDALLQHGAKCLLRDSRGRTPI 667
Cdd:PHA02874  265 PCDIDIIDILLYHKADISIKDNKGENPI 292

PHA02875

ankyrin repeat protein; Provisional

53-245

1.26e-12

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 70.79 E-value: 1.26e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  53 TPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANIN-AFDKKDRRAIHWAAYMGHIE 131
Cdd:PHA02875   37 SPIKLAMKFRDSEAIKLLMKHGAIPDVKYPDIESELHDAVEEGDVKAVEELLDLGKFADdVFYKDGMTPLHLATILKKLD 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 132 VVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQ 211
Cdd:PHA02875  117 IMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGANIDY 196

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1370483583 212 KNEKGFTPLHFAAASTHGALCLELLVGNGADVNM 245
Cdd:PHA02875  197 FGKNGCVAALCYAIENNKIDIVRLFIKRGADCNI 230

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

31-203

1.70e-12

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 71.20 E-value: 1.70e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  31 LEAVQVLLK-HSADVNARDKNWQTPLHIAAANKAVKCAEAL---VPLLSNVNV-SD-RAGRTALHHAAFSGHGEMVKLLL 104
Cdd:cd22192    30 VQAIKKLLKcPSCDLFQRGALGETALHVAALYDNLEAAVVLmeaAPELVNEPMtSDlYQGETALHIAVVNQNLNLVRELI 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 105 SRGANIN-------AFDKKDRRAIHW-------AAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLL 170
Cdd:cd22192   110 ARGADVVspratgtFFRPGPKNLIYYgehplsfAACVGNEEIVRLLIEHGADIRAQDSLGNTVLHILVLQPNKTFACQMY 189

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1370483583 171 DLGVDMNE----------PNAYGNTPLHVACYNGQDVVVNELI 203
Cdd:cd22192   190 DLILSYDKeddlqpldlvPNNQGLTPFKLAAKEGNIVMFQHLV 232

Ank_2

Ankyrin repeats (3 copies);

320-412

2.47e-12

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 63.60 E-value: 2.47e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 320 LHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTgADFNKKDKfGRSPLHYAAANCNYQCLF 399
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDN-GRTALHYAARSGHLEIVK 78

                          90
                  ....*....|...
gi 1370483583 400 ALVGSGASVNDLD 412
Cdd:pfam12796  79 LLLEKGADINVKD 91

PHA02798

ankyrin-like protein; Provisional

130-356

2.60e-12

ankyrin-like protein; Provisional

Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 70.25 E-value: 2.60e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 130 IEVVKLLVSHGAEVTCKDKKSYTPLHAAASS-----GMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGqdvVVNEL-- 202
Cdd:PHA02798   51 TDIVKLFINLGANVNGLDNEYSTPLCTILSNikdykHMLDIVKILIENGADINKKNSDGETPLYCLLSNG---YINNLei 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 203 ----IDCGAIVNQKNEKGFTPLHFAAASTHGAL--CLELLVGNGADVNMKSKDGKtplhMTALHGRFSRS---------Q 267
Cdd:PHA02798  128 llfmIENGADTTLLDKDGFTMLQVYLQSNHHIDieIIKLLLEKGVDINTHNNKEK----YDTLHCYFKYNidridadilK 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 268 TIIQSGAVIDCEDKNGNTPLhiaARYGHELLINT---------LITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSS 338
Cdd:PHA02798  204 LFVDNGFIINKENKSHKKKF---MEYLNSLLYDNkrfkknildFIFSYIDINQVDELGFNPLYYSVSHNNRKIFEYLLQL 280

                         250
                  ....*....|....*...
gi 1370483583 339 GFDIDTPDDFGRTCLHAA 356
Cdd:PHA02798  281 GGDINIITELGNTCLFTA 298

Ank_4

Ankyrin repeats (many copies);

84-137

9.16e-12

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 60.75 E-value: 9.16e-12

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1370483583  84 GRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLV 137
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

Ank_2

Ankyrin repeats (3 copies);

220-308

1.22e-11

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 61.67 E-value: 1.22e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 220 LHFAAASTHgALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSgAVIDCEDkNGNTPLHIAARYGHELLI 299
Cdd:pfam12796   1 LHLAAKNGN-LELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKD-NGRTALHYAARSGHLEIV 77


                  ....*....
gi 1370483583 300 NTLITSGAD 308
Cdd:pfam12796  78 KLLLEKGAD 86

PHA02874

ankyrin repeat protein; Provisional

541-805

1.37e-11

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 67.68 E-value: 1.37e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 541 ECVDVLINQGASILVKDYILKrTPIHAAATNGHSECLRLLIgnaEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKG 620
Cdd:PHA02874  105 DMIKTILDCGIDVNIKDAELK-TFLHYAIKKGDLESIKMLF---EYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKG 180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 621 ANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAkcllrdsrgrtpiHLSAACghigvlgallqsaasmdanpatadNHG 700
Cdd:PHA02874  181 AYANVKDNNGESPLHNAAEYGDYACIKLLIDHGN-------------HIMNKC------------------------KNG 223

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 701 YTALHWAC-YNghETCVELLLEQEVFQKTEGNAFSPLHCAVindNEGAAEMLIDTL--GASIVNATDSKGRTPLHAA-AF 776
Cdd:PHA02874  224 FTPLHNAIiHN--RSAIELLINNASINDQDIDGSTPLHHAI---NPPCDIDIIDILlyHKADISIKDNKGENPIDTAfKY 298

                         250       260
                  ....*....|....*....|....*....
gi 1370483583 777 TDHVECLQLLLSHNAQVNSVDSTGKTPLM 805
Cdd:PHA02874  299 INKDPVIKDIIANAVLIKEADKLKDSDFL 327

PLN03192

Voltage-dependent potassium channel; Provisional

37-182

2.04e-11

Voltage-dependent potassium channel; Provisional

Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 67.97 E-value: 2.04e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  37 LLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKK 116
Cdd:PLN03192  544 LLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIFRILYHFASISDPHAAG 623

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370483583 117 DrrAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAY 182
Cdd:PLN03192  624 D--LLCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLLIMNGADVDKANTD 687

Ank_2

Ankyrin repeats (3 copies);

187-280

4.01e-11

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 60.13 E-value: 4.01e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 187 LHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLvgNGADVNMKSkDGKTPLHMTALHGRFSRS 266
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLL--EHADVNLKD-NGRTALHYAARSGHLEIV 77

                          90
                  ....*....|....
gi 1370483583 267 QTIIQSGAVIDCED 280
Cdd:pfam12796  78 KLLLEKGADINVKD 91

PLN03192

Voltage-dependent potassium channel; Provisional

573-782

4.39e-11

Voltage-dependent potassium channel; Provisional

Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 67.20 E-value: 4.39e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 573 HSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQH 652
Cdd:PLN03192  501 HKELHDLNVGDLLGDNGGEHDDPNMASNLLTVASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKH 580

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 653 GAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDANPA---------------------------TADNHGYTALH 705
Cdd:PLN03192  581 ACNVHIRDANGNTALWNAISAKHHKIFRILYHFASISDPHAAgdllctaakrndltamkellkqglnvdSEDHQGATALQ 660

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 706 WACYNGHETCVELLLEQ--EVFQKTEGNAFSPLHC-AVINDNE-GAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVE 781
Cdd:PLN03192  661 VAMAEDHVDMVRLLIMNgaDVDKANTDDDFSPTELrELLQKRElGHSITIVDSVPADEPDLGRDGGSRPGRLQGTSSDNQ 740


                  .
gi 1370483583 782 C 782
Cdd:PLN03192  741 C 741

Ank_4

Ankyrin repeats (many copies);

118-170

4.59e-11

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 58.83 E-value: 4.59e-11

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1370483583 118 RRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLL 170
Cdd:pfam13637   2 LTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

Ank_4

Ankyrin repeats (many copies);

496-547

1.61e-10

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 57.28 E-value: 1.61e-10

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1370483583 496 SPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLI 547
Cdd:pfam13637   3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

PHA02876

ankyrin repeat protein; Provisional

30-178

1.80e-10

ankyrin repeat protein; Provisional

Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 65.08 E-value: 1.80e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  30 YLEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEM-VKLLLSRGA 108
Cdd:PHA02876  354 NKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFALCGTNPYMsVKTLIDRGA 433

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370483583 109 NINAFDKKDRRAIHWAAYMG-HIEVVKLLVSHGAEVTCKDKKSYTPLHAAAssGMISVVKYLLDLGVDMNE 178
Cdd:PHA02876  434 NVNSKNKDLSTPLHYACKKNcKLDVIEMLLDNGADVNAINIQNQYPLLIAL--EYHGIVNILLHYGAELRD 502

PHA02798

ankyrin-like protein; Provisional

8-254

2.77e-10

ankyrin-like protein; Provisional

Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 64.09 E-value: 2.77e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583   8 KSEPHCTPQLTLEMQKSLnflfyLEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSN---VNVSDRAG 84
Cdd:PHA02798   71 YSTPLCTILSNIKDYKHM-----LDIVKILIENGADINKKNSDGETPLYCLLSNGYINNLEILLFMIENgadTTLLDKDG 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  85 RTALHHAAFSGHG---EMVKLLLSRGANINAFDkkdrraiHWAAYmghievvkllvshgAEVTCKDKKSYTPLHAaassg 161
Cdd:PHA02798  146 FTMLQVYLQSNHHidiEIIKLLLEKGVDINTHN-------NKEKY--------------DTLHCYFKYNIDRIDA----- 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 162 miSVVKYLLDLGVDMNEPNAYGNTP----LHVACYNGQDVVVN--ELIDCGAIVNQKNEKGFTPLHFAAASTHGALClEL 235
Cdd:PHA02798  200 --DILKLFVDNGFIINKENKSHKKKfmeyLNSLLYDNKRFKKNilDFIFSYIDINQVDELGFNPLYYSVSHNNRKIF-EY 276

                         250
                  ....*....|....*....
gi 1370483583 236 LVGNGADVNMKSKDGKTPL 254
Cdd:PHA02798  277 LLQLGGDINIITELGNTCL 295

Ank_2

Ankyrin repeats (3 copies);

386-470

4.73e-10

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 57.05 E-value: 4.73e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 386 LHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDgKCLEYLLRNdANPGIRDkQGYNAVHYSAAYGHRLCL 465
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHL-EIVKLLLEH-ADVNLKD-NGRTALHYAARSGHLEIV 77


                  ....*
gi 1370483583 466 QLIAS 470
Cdd:pfam12796  78 KLLLE 82

PHA02874

ankyrin repeat protein; Provisional

760-920

4.73e-10

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 63.06 E-value: 4.73e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 760 VNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSAsAELTLQDNSKNTALH 839
Cdd:PHA02874  117 VNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKG-AYANVKDNNGESPLH 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 840 LACSKGHETSALLILEKITdrNLINATNAALqTPLHVAARNGLTMVvqELLGKGASVLAVDENGYTP---ALACAPNKDV 916
Cdd:PHA02874  196 NAAEYGDYACIKLLIDHGN--HIMNKCKNGF-TPLHNAIIHNRSAI--ELLINNASINDQDIDGSTPlhhAINPPCDIDI 270


                  ....
gi 1370483583 917 ADCL 920
Cdd:PHA02874  271 IDIL 274

Ank_4

Ankyrin repeats (many copies);

151-195

4.85e-10

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 55.74 E-value: 4.85e-10

                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1370483583 151 YTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQ 195
Cdd:pfam13637   2 LTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGN 46

PHA03100

ankyrin repeat protein; Provisional

510-691

5.89e-10

ankyrin repeat protein; Provisional

Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 62.76 E-value: 5.89e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 510 LEVLVQSLLDLDVRNSSGRTPLDLAAFK--GHVECVDVLINQGASILVKDYILKrTPIHAAATNGH--SECLRLLIgnae 585
Cdd:PHA03100   89 VKLLLEYGANVNAPDNNGITPLLYAISKksNSYSIVEYLLDNGANVNIKNSDGE-NLLHLYLESNKidLKILKLLI---- 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 586 pQNAVDIqdgngqtplmlsvlNGhTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRT 665
Cdd:PHA03100  164 -DKGVDI--------------NA-KNRVNYLLSYGVPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDT 227

                         170       180
                  ....*....|....*....|....*.
gi 1370483583 666 PIHLSAACGHIGVLGALLQSAASMDA 691
Cdd:PHA03100  228 PLHIAILNNNKEIFKLLLNNGPSIKT 253

PHA02878

ankyrin repeat protein; Provisional

634-906

5.91e-10

ankyrin repeat protein; Provisional

Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 62.98 E-value: 5.91e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 634 LHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLsaACGHIGVLGA--LLQSAasmdanpaTADNHGYT--ALHWACY 709
Cdd:PHA02878   41 LHQAVEARNLDVVKSLLTRGHNVNQPDHRDLTPLHI--ICKEPNKLGMkeMIRSI--------NKCSVFYTlvAIKDAFN 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 710 NGHETCVELLLeqevFQKTEGNAFSPLHCAVINDNEGAAEMLIDTL----GASIVNATDSKGRTPLHAAAFTDHVECLQL 785
Cdd:PHA02878  111 NRNVEIFKIIL----TNRYKNIQTIDLVYIDKKSKDDIIEAEITKLllsyGADINMKDRHKGNTALHYATENKDQRLTEL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 786 LLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSAsAELTLQDNSKNTALHLACSKGHETSAL-LILEKITDrnlIN 864
Cdd:PHA02878  187 LLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENG-ASTDARDKCGNTPLHISVGYCKDYDILkLLLEHGVD---VN 262

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1370483583 865 ATNAALQ-TPLHVAARNglTMVVQELLGKGASVLAVDENGYTP 906
Cdd:PHA02878  263 AKSYILGlTALHSSIKS--ERKLKLLLEYGADINSLNSYKLTP 303

PHA02876

ankyrin repeat protein; Provisional

748-913

8.10e-10

ankyrin repeat protein; Provisional

Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 62.77 E-value: 8.10e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 748 AEMLIDtlGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSAS--- 824
Cdd:PHA02876  161 AEMLLE--GGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIIDNRSnin 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 825 -AELTLQDNSKNTALhlacskghETSALLILEKITdrnlINATNAALQTPLHVAARN-GLTMVVQELLGKGASVLAVDEN 902
Cdd:PHA02876  239 kNDLSLLKAIRNEDL--------ETSLLLYDAGFS----VNSIDDCKNTPLHHASQApSLSRLVPKLLERGADVNAKNIK 306

                         170
                  ....*....|.
gi 1370483583 903 GYTPALACAPN 913
Cdd:PHA02876  307 GETPLYLMAKN 317

PHA02875

ankyrin repeat protein; Provisional

230-444

8.47e-10

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 61.93 E-value: 8.47e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 230 ALCLELLVGN----------GADVNMKSKDGKTPLHMTAlhgRFSRSQTI---IQSGAVIDCEDKNGNTPLHIAARYGHE 296
Cdd:PHA02875    5 ALCDAILFGEldiarrlldiGINPNFEIYDGISPIKLAM---KFRDSEAIkllMKHGAIPDVKYPDIESELHDAVEEGDV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 297 LLINTLITSGA---DTAKRgiHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGA 373
Cdd:PHA02875   82 KAVEELLDLGKfadDVFYK--DGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKA 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370483583 374 DFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGI 444
Cdd:PHA02875  160 CLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGANIDYFGKNGCVAALCYAIENNKIDIVRLFIKRGADCNI 230

PHA02878

ankyrin repeat protein; Provisional

490-721

9.27e-10

ankyrin repeat protein; Provisional

Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 62.20 E-value: 9.27e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 490 DNRATiSPLHLAAYHGHHQALEVLVQSLLDLDVRNSsgRTPLDLAAFKGHVECVD-VLINQGASILVKDYILKRTPIHAA 568
Cdd:PHA02878   67 DHRDL-TPLHIICKEPNKLGMKEMIRSINKCSVFYT--LVAIKDAFNNRNVEIFKiILTNRYKNIQTIDLVYIDKKSKDD 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 569 ATNghSECLRLLIGNAEPQNAVDIQDGNgqTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDA 648
Cdd:PHA02878  144 IIE--AEITKLLLSYGADINMKDRHKGN--TALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHI 219

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370483583 649 LLQHGAKCLLRDSRGRTPIHLSAA-CGHIGVLGALLQSAASMDANPATAdnhGYTALHWACYNghETCVELLLE 721
Cdd:PHA02878  220 LLENGASTDARDKCGNTPLHISVGyCKDYDILKLLLEHGVDVNAKSYIL---GLTALHSSIKS--ERKLKLLLE 288

PHA02875

ankyrin repeat protein; Provisional

31-142

1.26e-09

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 61.55 E-value: 1.26e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  31 LEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANI 110
Cdd:PHA02875  115 LDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGANI 194

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1370483583 111 NAFDKK-DRRAIHWAAYMGHIEVVKLLVSHGAE 142
Cdd:PHA02875  195 DYFGKNgCVAALCYAIENNKIDIVRLFIKRGAD 227

Ank_2

Ankyrin repeats (3 copies);

419-524

1.36e-09

Ankyrin repeats (3 copies);

Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 55.89 E-value: 1.36e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 419 LHYAATSDtDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDvlMETSGTdmlsdsdnratiSPL 498
Cdd:pfam12796   1 LHLAAKNG-NLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVN--LKDNGR------------TAL 65

                          90       100
                  ....*....|....*....|....*.
gi 1370483583 499 HLAAYHGHHQALEVLVQSLLDLDVRN 524
Cdd:pfam12796  66 HYAARSGHLEIVKLLLEKGADINVKD 91

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

529-669

1.52e-09

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 61.95 E-value: 1.52e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 529 TPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNA-----EPQNAVDIQdgnGQTPLML 603
Cdd:cd22192    19 SPLLLAAKENDVQAIKKLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAApelvnEPMTSDLYQ---GETALHI 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 604 SVLNGHTDCVYSLLNKGANV--------------DAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHL 669
Cdd:cd22192    96 AVVNQNLNLVRELIARGADVvspratgtffrpgpKNLIYYGEHPLSFAACVGNEEIVRLLIEHGADIRAQDSLGNTVLHI 175

PHA02875

ankyrin repeat protein; Provisional

527-722

1.80e-09

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 61.16 E-value: 1.80e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 527 GRTPLDLAAFKGHVECVDVLINQGASILVKdYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNgqTPLMLSVL 606
Cdd:PHA02875   35 GISPIKLAMKFRDSEAIKLLMKHGAIPDVK-YPDIESELHDAVEEGDVKAVEELLDLGKFADDVFYKDGM--TPLHLATI 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 607 NGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSA 686
Cdd:PHA02875  112 LKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSG 191

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1370483583 687 ASMDanpATADNHGYTALHWACYNGHETCVELLLEQ 722
Cdd:PHA02875  192 ANID---YFGKNGCVAALCYAIENNKIDIVRLFIKR 224

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

152-289

2.66e-09

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 61.18 E-value: 2.66e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 152 TPLHAAASSGMISVVKYLLDL-GVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCG-AIVNQKNE----KGFTPLHFAAA 225
Cdd:cd22192    19 SPLLLAAKENDVQAIKKLLKCpSCDLFQRGALGETALHVAALYDNLEAAVVLMEAApELVNEPMTsdlyQGETALHIAVV 98

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370483583 226 STHGALcLELLVGNGADVN---------MKSKD-----GKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHI 289
Cdd:cd22192    99 NQNLNL-VRELIARGADVVspratgtffRPGPKnliyyGEHPLSFAACVGNEEIVRLLIEHGADIRAQDSLGNTVLHI 175

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

88-170

3.37e-09

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 60.68 E-value: 3.37e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  88 LHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVK 167
Cdd:PTZ00322   86 LCQLAASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQ 165


                  ...
gi 1370483583 168 YLL 170
Cdd:PTZ00322  166 LLS 168

PHA02878

ankyrin repeat protein; Provisional

401-606

3.62e-09

ankyrin repeat protein; Provisional

Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 60.28 E-value: 3.62e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 401 LVGSGASVNDLDE-RGCTPLHYAATsDTDGKCLEYLLRNDANPGIRDKqgynavhysaayghrlclqliasetpldvlme 479
Cdd:PHA02878  153 LLSYGADINMKDRhKGNTALHYATE-NKDQRLTELLLSYGANVNIPDK-------------------------------- 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 480 tsgtdmlsdSDNratiSPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAfkGHVECVDV---LINQGASILVK 556
Cdd:PHA02878  200 ---------TNN----SPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISV--GYCKDYDIlklLLEHGVDVNAK 264

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1370483583 557 DYILKRTPIHAAAtngHSE-CLRLLIGNAEPQNAVDIQDgngQTPLMLSVL 606
Cdd:PHA02878  265 SYILGLTALHSSI---KSErKLKLLLEYGADINSLNSYK---LTPLSSAVK 309

PHA02946

ankyin-like protein; Provisional

34-220

6.07e-09

ankyin-like protein; Provisional

Pssm-ID: 165256 [Multi-domain] Cd Length: 446 Bit Score: 59.68 E-value: 6.07e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  34 VQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHG--EMVKLLLSRGANIN 111
Cdd:PHA02946   55 VEELLHRGYSPNETDDDGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLYYLSGTDDEviERINLLVQYGAKIN 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 112 AFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDK--KSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHV 189
Cdd:PHA02946  135 NSVDEEGCGPLLACTDPSERVFKKIMSIGFEARIVDKfgKNHIHRHLMSDNPKASTISWMMKLGISPSKPDHDGNTPLHI 214

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1370483583 190 ACYNG-QDVVVNELIDCGAIVNQKNEKGFTPL 220
Cdd:PHA02946  215 VCSKTvKNVDIINLLLPSTDVNKQNKFGDSPL 246

Ank_4

Ankyrin repeats (many copies);

53-104

7.89e-09

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 52.66 E-value: 7.89e-09

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1370483583  53 TPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLL 104
Cdd:pfam13637   3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

Ank_4

Ankyrin repeats (many copies);

767-820

8.53e-09

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 52.28 E-value: 8.53e-09

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1370483583 767 GRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLV 820
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

PLN03192

Voltage-dependent potassium channel; Provisional

91-249

1.20e-08

Voltage-dependent potassium channel; Provisional

Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 59.11 E-value: 1.20e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  91 AAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLL 170
Cdd:PLN03192  532 VASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIFRILY 611

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370483583 171 DLGvDMNEPNAYGNTpLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALcLELLVGNGADVNMKSKD 249
Cdd:PLN03192  612 HFA-SISDPHAAGDL-LCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDM-VRLLIMNGADVDKANTD 687

PLN03192

Voltage-dependent potassium channel; Provisional

30-145

1.87e-08

Voltage-dependent potassium channel; Provisional

Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 58.34 E-value: 1.87e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  30 YLEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSnvnVSD-RAGRTALHHAAFSGHGEMVKLLLSRGA 108
Cdd:PLN03192  570 YEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIFRILYHFAS---ISDpHAAGDLLCTAAKRNDLTAMKELLKQGL 646

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1370483583 109 NINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTC 145
Cdd:PLN03192  647 NVDSEDHQGATALQVAMAEDHVDMVRLLIMNGADVDK 683

PLN03192

Voltage-dependent potassium channel; Provisional

389-637

1.97e-08

Voltage-dependent potassium channel; Provisional

Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 58.34 E-value: 1.97e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 389 AAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDgKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHrlclqli 468
Cdd:PLN03192  532 VASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYE-DCVLVLLKHACNVHIRDANGNTALWNAISAKH------- 603

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 469 asETPLDVLMETSgtdmlSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLIN 548
Cdd:PLN03192  604 --HKIFRILYHFA-----SISDPHAAGDLLCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLLIM 676

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 549 QGASIlvkdyilkrtpIHAAATNGHS-ECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCvySLLNKGANvdaKD 627
Cdd:PLN03192  677 NGADV-----------DKANTDDDFSpTELRELLQKRELGHSITIVDSVPADEPDLGRDGGSRPG--RLQGTSSD---NQ 740

                         250
                  ....*....|
gi 1370483583 628 KWGRTALHRG 637
Cdd:PLN03192  741 CRPRVSIYKG 750

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

723-834

1.98e-08

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 58.37 E-value: 1.98e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 723 EVFQKTEGNAFSPLHCAVIND--NEGAAEMLI----------DTLGASIV-------NATDSKGRTPLHAAAFTDHVECL 783
Cdd:PTZ00322   52 EALEATENKDATPDHNLTTEEviDPVVAHMLTvelcqlaasgDAVGARILltggadpNCRDYDGRTPLHIACANGHVQVV 131

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1370483583 784 QLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSK 834
Cdd:PTZ00322  132 RVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRHSQCHFELGANAK 182

Ank_4

Ankyrin repeats (many copies);

527-581

2.34e-08

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 51.12 E-value: 2.34e-08

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1370483583 527 GRTPLDLAAFKGHVECVDVLINQGASILVKDYiLKRTPIHAAATNGHSECLRLLI 581
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLEKGADINAVDG-NGETALHFAASNGNVEVLKLLL 54

PHA02874

ankyrin repeat protein; Provisional

736-906

3.27e-08

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 57.28 E-value: 3.27e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 736 LHCAVINDNEGAAEMLIDtLGASiVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNT 815
Cdd:PHA02874  128 LHYAIKKGDLESIKMLFE-YGAD-VNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYAC 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 816 VEMLVSSASaELTLQDNSKNTALHLACSkgHETSALLILekITDRNlINATNAALQTPLHVAARNGLTM-VVQELLGKGA 894
Cdd:PHA02874  206 IKLLIDHGN-HIMNKCKNGFTPLHNAII--HNRSAIELL--INNAS-INDQDIDGSTPLHHAINPPCDIdIIDILLYHKA 279

                         170
                  ....*....|..
gi 1370483583 895 SVLAVDENGYTP 906
Cdd:PHA02874  280 DISIKDNKGENP 291

PHA02875

ankyrin repeat protein; Provisional

704-876

3.28e-08

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 56.92 E-value: 3.28e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 704 LHWACYNGHETCVELLLE-----QEVFQKtEGNafSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKgrTPLHAAAFTD 778
Cdd:PHA02875   72 LHDAVEEGDVKAVEELLDlgkfaDDVFYK-DGM--TPLHLATILKKLDIMKLLIARGADPDIPNTDKF--SPLHLAVMMG 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 779 HVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKIT 858
Cdd:PHA02875  147 DIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGANIDYFGKNGCVAALCYAIENNKIDIVRLFIKRGA 226

                         170
                  ....*....|....*...
gi 1370483583 859 DRNLINATNAALQTPLHV 876
Cdd:PHA02875  227 DCNIMFMIEGEECTILDM 244

trp

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ...

518-741

4.27e-08

Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 57.40 E-value: 4.27e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 518 LDLDVRNSSGRTPLDLAAFKG-HVECVDVLINQGASILVKDyilkrTPIHAAATNGH---SECLRLLIGNAE----PQNA 589
Cdd:TIGR00870  43 LNINCPDRLGRSALFVAAIENeNLELTELLLNLSCRGAVGD-----TLLHAISLEYVdavEAILLHLLAAFRksgpLELA 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 590 VDIQDGN---GQTPLMLSVLNGHTDCVYSLLNKGANVDAKDK--------------WGRTALHRGAVTGHEECVDALLQH 652
Cdd:TIGR00870 118 NDQYTSEftpGITALHLAAHRQNYEIVKLLLERGASVPARACgdffvksqgvdsfyHGESPLNAAACLGSPSIVALLSED 197

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 653 GAKCLLRDSRGRTPIHLSAACGHIGVLGALL-----QSAASMDANPATAD------NH-GYTALHWACYNGHETCVELLL 720
Cdd:TIGR00870 198 PADILTADSLGNTLLHLLVMENEFKAEYEELscqmyNFALSLLDKLRDSKelevilNHqGLTPLKLAAKEGRIVLFRLKL 277

                         250       260
                  ....*....|....*....|..
gi 1370483583 721 EQEVFQKT-EGNAFSPLHCAVI 741
Cdd:TIGR00870 278 AIKYKQKKfVAWPNGQQLLSLY 299

PHA02859

ankyrin repeat protein; Provisional

26-194

4.63e-08

ankyrin repeat protein; Provisional

Pssm-ID: 165195 [Multi-domain] Cd Length: 209 Bit Score: 54.44 E-value: 4.63e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  26 NFLFY------LEAVQvllKHSADVNARDKNWQTPLHIAAANKAV--KCAEALVPLLSNVNVSDRA-GRTALHHAAFSGH 96
Cdd:PHA02859   23 NPLFYyvekddIEGVK---KWIKFVNDCNDLYETPIFSCLEKDKVnvEILKFLIENGADVNFKTRDnNLSALHHYLSFNK 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  97 G---EMVKLLLSRGANINAFDKKDRRAIHwaAYMGH----IEVVKLLVSHGAEVTCKDKK------SYTPLHAAASsgmi 163
Cdd:PHA02859  100 NvepEILKILIDSGSSITEEDEDGKNLLH--MYMCNfnvrINVIKLLIDSGVSFLNKDFDnnnilySYILFHSDKK---- 173

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1370483583 164 sVVKYLLDLGVDMNEPNAYGNTPLHVACYNG 194
Cdd:PHA02859  174 -IFDFLTSLGIDINETNKSGYNCYDLIKFRN 203

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

133-205

4.86e-08

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 56.83 E-value: 4.86e-08

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370483583 133 VKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDC 205
Cdd:PTZ00322   98 ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRH 170

PLN03192

Voltage-dependent potassium channel; Provisional

127-318

5.19e-08

Voltage-dependent potassium channel; Provisional

Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 57.19 E-value: 5.19e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 127 MGHIEVVKLLVSHGAEVTckDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCG 206
Cdd:PLN03192  504 LHDLNVGDLLGDNGGEHD--DPNMASNLLTVASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHA 581

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 207 AIVNQKNEKGFTPLHFAAASTHGALcLELLVGNGADVNMKSkdGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTP 286
Cdd:PLN03192  582 CNVHIRDANGNTALWNAISAKHHKI-FRILYHFASISDPHA--AGDLLCTAAKRNDLTAMKELLKQGLNVDSEDHQGATA 658

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1370483583 287 LHIAARYGHELLINTLITSGADTAKRGIHGMF 318
Cdd:PLN03192  659 LQVAMAEDHVDMVRLLIMNGADVDKANTDDDF 690

PHA02989

ankyrin repeat protein; Provisional

34-271

5.19e-08

ankyrin repeat protein; Provisional

Pssm-ID: 222954 [Multi-domain] Cd Length: 494 Bit Score: 56.67 E-value: 5.19e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  34 VQVLLKHSADVNARDKNWQTPLhiaaankavkcaealVPLLSNVNVSDRagrtalhhaafsghgEMVKLLLSRGANINaf 113
Cdd:PHA02989   91 VKLLLKFGADINLKTFNGVSPI---------------VCFIYNSNINNC---------------DMLRFLLSKGINVN-- 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 114 DKKDRRA-----IHWAAYMGHIEVVKLLVSHGaeVTCKDKKSY---TPLHAAASSGM----ISVVKYLLDLGVDMNEPNA 181
Cdd:PHA02989  139 DVKNSRGynllhMYLESFSVKKDVIKILLSFG--VNLFEKTSLyglTPMNIYLRNDIdvisIKVIKYLIKKGVNIETNNN 216

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 182 YGNTPL------HVACYNGQDVVVNeLIDCGAIVNQKNEKGFTPLHFAA-ASTHGALCLELLVGNgaDVNMKSKDGKTPL 254
Cdd:PHA02989  217 GSESVLesfldnNKILSKKEFKVLN-FILKYIKINKKDKKGFNPLLISAkVDNYEAFNYLLKLGD--DIYNVSKDGDTVL 293

                         250
                  ....*....|....*..
gi 1370483583 255 HMTALHGRFSRSQTIIQ 271
Cdd:PHA02989  294 TYAIKHGNIDMLNRILQ 310

Ank_4

Ankyrin repeats (many copies);

630-683

5.54e-08

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 49.97 E-value: 5.54e-08

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1370483583 630 GRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALL 683
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

PLN03192

Voltage-dependent potassium channel; Provisional

223-377

5.90e-08

Voltage-dependent potassium channel; Provisional

Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 56.80 E-value: 5.90e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 223 AAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTL 302
Cdd:PLN03192  531 TVASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIFRIL 610

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1370483583 303 --ITSGADTAKRGIhgmfPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNK 377
Cdd:PLN03192  611 yhFASISDPHAAGD----LLCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLLIMNGADVDK 683

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

649-822

6.36e-08

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 56.56 E-value: 6.36e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 649 LLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDANPATADNH-GYTALHWACYNGHETCVELLLEQ----- 722
Cdd:cd22192    37 LKCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAAPELVNEPMTSDLYqGETALHIAVVNQNLNLVRELIARgadvv 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 723 ------EVFQKTEGNAF----SPLHCAVINDNEGAAEMLIDTlGASIVnATDSKGRTPLHAAAF----TDHVECLQLLLS 788
Cdd:cd22192   117 spratgTFFRPGPKNLIyygeHPLSFAACVGNEEIVRLLIEH-GADIR-AQDSLGNTVLHILVLqpnkTFACQMYDLILS 194

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1370483583 789 HNAQVNSV------DSTGKTPLMMAAENGQTNTVEMLVSS 822
Cdd:cd22192   195 YDKEDDLQpldlvpNNQGLTPFKLAAKEGNIVMFQHLVQK 234

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

34-105

6.90e-08

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 56.45 E-value: 6.90e-08

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370483583  34 VQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLS 105
Cdd:PTZ00322   98 ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSR 169

TRPV3

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 3; TRPV3 is a ...

764-892

9.21e-08

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 3; TRPV3 is a temperature-sensitive Transient Receptor Potential (TRP) ion channel that is activated by warm temperatures, synthetic small-molecule chemicals, and natural compounds from plants. TRPV3 function is regulated by physiological factors such as extracellular divalent cations and acidic pH, intracellular adenosine triphosphate, membrane voltage, and arachidonic acid. It is expressed in both neuronal and non-neuronal tissues including epidermal keratinocytes, epithelial cells in the gut, endothelial cells in blood vessels, and neurons in dorsal root ganglia and CNS. TRPV3 null mice have abnormal hair morphogenesis and compromised skin barrier function. It may play roles in inflammatory skin disorders, such as itch and pain sensation. TRPV3 is also expressed by many neuronal and non-neuronal tissues, showing that TRPV3 might play roles in other unknown cellular and physiological functions. TRPV3 belongs to the vanilloid TRP subfamily (TRPV), named after the founding member vanilloid receptor 1 (TRPV1). The structure of TRPV shows the typical topology features of all TRP ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains.

Pssm-ID: 411978 [Multi-domain] Cd Length: 680 Bit Score: 56.31 E-value: 9.21e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 764 DSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDST--------------GKTPLMMAAENGQTNTVEMLVSSASAELTL 829
Cdd:cd22194   138 AYEGQTALNIAIERRQGDIVKLLIAKGADVNAHAKGvffnpkykhegfyfGETPLALAACTNQPEIVQLLMEKESTDITS 217

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370483583 830 QDNSKNTALHLAC-----SKGHETSAL----LILEKITDRNLINATNAALQTPLHVAARNGLTMVVQELLGK 892
Cdd:cd22194   218 QDSRGNTVLHALVtvaedSKTQNDFVKrmydMILLKSENKNLETIRNNEGLTPLQLAAKMGKAEILKYILSR 289

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

736-892

1.01e-07

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 55.79 E-value: 1.01e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 736 LHCAVINDNEGAAEMLIDTLGASIVNATDS---KGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDST------------- 799
Cdd:cd22192    55 LHVAALYDNLEAAVVLMEAAPELVNEPMTSdlyQGETALHIAVVNQNLNLVRELIARGADVVSPRATgtffrpgpknliy 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 800 -GKTPLMMAAENGQTNTVEMLVsSASAELTLQDNSKNTALHLACSKGHETSA------LLILEK-ITDRNLINATNAALQ 871
Cdd:cd22192   135 yGEHPLSFAACVGNEEIVRLLI-EHGADIRAQDSLGNTVLHILVLQPNKTFAcqmydlILSYDKeDDLQPLDLVPNNQGL 213

                         170       180
                  ....*....|....*....|.
gi 1370483583 872 TPLHVAARNGLTMVVQELLGK 892
Cdd:cd22192   214 TPFKLAAKEGNIVMFQHLVQK 234

PHA02875

ankyrin repeat protein; Provisional

761-923

1.13e-07

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 55.38 E-value: 1.13e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 761 NATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHL 840
Cdd:PHA02875   29 NFEIYDGISPIKLAMKFRDSEAIKLLMKHGAIPDVKYPDIESELHDAVEEGDVKAVEELLDLGKFADDVFYKDGMTPLHL 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 841 AC-SKGHETSALLILEKiTDRNLINATNAalqTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADC 919
Cdd:PHA02875  109 ATiLKKLDIMKLLIARG-ADPDIPNTDKF---SPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAIC 184


                  ....
gi 1370483583 920 LALI 923
Cdd:PHA02875  185 KMLL 188

Ank_4

Ankyrin repeats (many copies);

382-436

2.43e-07

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 48.42 E-value: 2.43e-07

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1370483583 382 GRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDtDGKCLEYLL 436
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNG-NVEVLKLLL 54

PHA02875

ankyrin repeat protein; Provisional

734-925

2.78e-07

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 54.23 E-value: 2.78e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 734 SPLHCAVINDNEGAAEMLIDtLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQT 813
Cdd:PHA02875   70 SELHDAVEEGDVKAVEELLD-LGKFADDVFYKDGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDI 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 814 NTVEMLVSsasaeltlqdnskntalHLACskghetsallilekitdrnlINATNAALQTPLHVAARNGLTMVVQELLGKG 893
Cdd:PHA02875  149 KGIELLID-----------------HKAC--------------------LDIEDCCGCTPLIIAMAKGDIAICKMLLDSG 191

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1370483583 894 ASVLAVDENGYTPALACAPNKDVADCLALILA 925
Cdd:PHA02875  192 ANIDYFGKNGCVAALCYAIENNKIDIVRLFIK 223

PLN03192

Voltage-dependent potassium channel; Provisional

746-906

2.85e-07

Voltage-dependent potassium channel; Provisional

Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 54.49 E-value: 2.85e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 746 GAAEMLIDTLGASI-VNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSAS 824
Cdd:PLN03192  536 GNAALLEELLKAKLdPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIFRILYHFAS 615

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 825 AeltlqdNSKNTALHLACSKGHETSaLLILEKITDRNL-INATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVD-EN 902
Cdd:PLN03192  616 I------SDPHAAGDLLCTAAKRND-LTAMKELLKQGLnVDSEDHQGATALQVAMAEDHVDMVRLLIMNGADVDKANtDD 688


                  ....
gi 1370483583 903 GYTP 906
Cdd:PLN03192  689 DFSP 692

PHA02875

ankyrin repeat protein; Provisional

596-843

2.92e-07

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 53.84 E-value: 2.92e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 596 NGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAkcLLRD---SRGRTPIHLSAA 672
Cdd:PHA02875   34 DGISPIKLAMKFRDSEAIKLLMKHGAIPDVKYPDIESELHDAVEEGDVKAVEELLDLGK--FADDvfyKDGMTPLHLATI 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 673 CGHIGVLGALLQSAASMDAnPATadnhgytalhwacynghetcvellleqevfqktegNAFSPLHCAVINDNEGAAEMLI 752
Cdd:PHA02875  112 LKKLDIMKLLIARGADPDI-PNT-----------------------------------DKFSPLHLAVMMGDIKGIELLI 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 753 DTlgASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLM-MAAENGQTNTVEMLVS--SASAELTL 829
Cdd:PHA02875  156 DH--KACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGANIDYFGKNGCVAALcYAIENNKIDIVRLFIKrgADCNIMFM 233

                         250
                  ....*....|....
gi 1370483583 830 QDNSKNTALHLACS 843
Cdd:PHA02875  234 IEGEECTILDMICN 247

PHA02859

ankyrin repeat protein; Provisional

150-308

4.57e-07

ankyrin repeat protein; Provisional

Pssm-ID: 165195 [Multi-domain] Cd Length: 209 Bit Score: 51.74 E-value: 4.57e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 150 SYT-PLHAAASSGMISVVKYLLDLgvdMNEPNAYGNTPLHvACYNGQDVVVNE---LIDCGAIVNQK-NEKGFTPLHFAA 224
Cdd:PHA02859   20 RYCnPLFYYVEKDDIEGVKKWIKF---VNDCNDLYETPIF-SCLEKDKVNVEIlkfLIENGADVNFKtRDNNLSALHHYL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 225 ASTHGAL--CLELLVGNGADVNMKSKDGKTPLH--MTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLI- 299
Cdd:PHA02859   96 SFNKNVEpeILKILIDSGSSITEEDEDGKNLLHmyMCNFNVRINVIKLLIDSGVSFLNKDFDNNNILYSYILFHSDKKIf 175


                  ....*....
gi 1370483583 300 NTLITSGAD 308
Cdd:PHA02859  176 DFLTSLGID 184

PHA02798

ankyrin-like protein; Provisional

198-422

5.95e-07

ankyrin-like protein; Provisional

Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 53.30 E-value: 5.95e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 198 VVNELIDCGAIVNQKNEKGFTPLHFAAAS----THGALCLELLVGNGADVNMKSKDGKTPLHmTALHGRFSRSQTI---- 269
Cdd:PHA02798   53 IVKLFINLGANVNGLDNEYSTPLCTILSNikdyKHMLDIVKILIENGADINKKNSDGETPLY-CLLSNGYINNLEIllfm 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 270 IQSGAVIDCEDKNGNTPLHIAARYGHEL---LINTLITSGADTAKRG-------IHGMFPLHLAALSgfSDCCRKLLSSG 339
Cdd:PHA02798  132 IENGADTTLLDKDGFTMLQVYLQSNHHIdieIIKLLLEKGVDINTHNnkekydtLHCYFKYNIDRID--ADILKLFVDNG 209

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 340 FDIDTPDDFGRTCLHAAAAGGNLECLNLLLN------TGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDE 413
Cdd:PHA02798  210 FIINKENKSHKKKFMEYLNSLLYDNKRFKKNildfifSYIDINQVDELGFNPLYYSVSHNNRKIFEYLLQLGGDINIITE 289


                  ....*....
gi 1370483583 414 RGCTPLHYA 422
Cdd:PHA02798  290 LGNTCLFTA 298

PHA02874

ankyrin repeat protein; Provisional

747-906

6.22e-07

ankyrin repeat protein; Provisional

Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 53.04 E-value: 6.22e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 747 AAEMLIDTLGaSIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVssasae 826
Cdd:PHA02874   16 AIEKIIKNKG-NCINISVDETTTPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLI------ 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 827 ltlqDNSKNTA-LHLACSKGHETSAllILEKITDrnlINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYT 905
Cdd:PHA02874   89 ----DNGVDTSiLPIPCIEKDMIKT--ILDCGID---VNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCY 159


                  .
gi 1370483583 906 P 906
Cdd:PHA02874  160 P 160

Ank_4

Ankyrin repeats (many copies);

734-787

7.59e-07

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 46.88 E-value: 7.59e-07

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1370483583 734 SPLHCAVINDNEGAAEMLIDTlGASIvNATDSKGRTPLHAAAFTDHVECLQLLL 787
Cdd:pfam13637   3 TALHAAAASGHLELLRLLLEK-GADI-NAVDGNGETALHFAASNGNVEVLKLLL 54

trp

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ...

31-191

1.16e-06

Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 52.78 E-value: 1.16e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  31 LEAVQVLLKHSADVNARDknwqTPLHIAAANKAVKCAEALVPLLSN---------VNVSDR----AGRTALHHAAFSGHG 97
Cdd:TIGR00870  66 LELTELLLNLSCRGAVGD----TLLHAISLEYVDAVEAILLHLLAAfrksgplelANDQYTseftPGITALHLAAHRQNY 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  98 EMVKLLLSRGANINA------FDKKDRRA--------IHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAA----- 158
Cdd:TIGR00870 142 EIVKLLLERGASVPAracgdfFVKSQGVDsfyhgespLNAAACLGSPSIVALLSEDPADILTADSLGNTLLHLLVmenef 221

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1370483583 159 -------SSGMISVVKYLLDLGVDMNE----PNAYGNTPLHVAC 191
Cdd:TIGR00870 222 kaeyeelSCQMYNFALSLLDKLRDSKEleviLNHQGLTPLKLAA 265

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

225-294

1.22e-06

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 52.59 E-value: 1.22e-06

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 225 ASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYG 294
Cdd:PTZ00322   90 AASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENG 159

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

218-423

1.36e-06

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 52.32 E-value: 1.36e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 218 TPLhFAAASTHGALCLE-LLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGA-----VIDCEDKNGNTPLHIAA 291
Cdd:cd22192    19 SPL-LLAAKENDVQAIKkLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAAPelvnePMTSDLYQGETALHIAV 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 292 RYGHELLINTLITSGADTAKRGIHGMFplhlaalsgFSDCCRKLLSsgfdidtpddFGRTCLHAAAAGGNLECLNLLLNT 371
Cdd:cd22192    98 VNQNLNLVRELIARGADVVSPRATGTF---------FRPGPKNLIY----------YGEHPLSFAACVGNEEIVRLLIEH 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370483583 372 GADFNKKDKFGRSPLHYAA--ANCNYQC-----LFALVGSGASVNdLD----ERGCTPLHYAA 423
Cdd:cd22192   159 GADIRAQDSLGNTVLHILVlqPNKTFACqmydlILSYDKEDDLQP-LDlvpnNQGLTPFKLAA 220

Ank_4

Ankyrin repeats (many copies);

599-650

1.55e-06

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 46.11 E-value: 1.55e-06

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1370483583 599 TPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALL 650
Cdd:pfam13637   3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

Ank_4

Ankyrin repeats (many copies);

562-617

1.84e-06

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 45.73 E-value: 1.84e-06

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370483583 562 RTPIHAAATNGHSECLRLLIGNAEPqnaVDIQDGNGQTPLMLSVLNGHTDCVYSLL 617
Cdd:pfam13637   2 LTALHAAAASGHLELLRLLLEKGAD---INAVDGNGETALHFAASNGNVEVLKLLL 54

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

802-896

2.62e-06

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 51.17 E-value: 2.62e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 802 TPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEkiTDRNLIN-ATNAAL---QTPLHVA 877
Cdd:cd22192    19 SPLLLAAKENDVQAIKKLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLME--AAPELVNePMTSDLyqgETALHIA 96

                          90
                  ....*....|....*....
gi 1370483583 878 ARNGLTMVVQELLGKGASV 896
Cdd:cd22192    97 VVNQNLNLVRELIARGADV 115

Ank_5

Ankyrin repeats (many copies);

136-190

2.86e-06

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 45.42 E-value: 2.86e-06

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370483583 136 LVSHG-AEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVA 190
Cdd:pfam13857   1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

134-318

3.84e-06

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 50.78 E-value: 3.84e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 134 KLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDM-NEP---NAY-GNTPLHVACYNGQDVVVNELIDCGAI 208
Cdd:cd22192    35 KLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAAPELvNEPmtsDLYqGETALHIAVVNQNLNLVRELIARGAD 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 209 VN---------QKNEK-----GFTPLHFAAASTHGALcLELLVGNGADVNMKSKDGKTPLHMTALhgrfsrsqtiiQSGA 274
Cdd:cd22192   115 VVspratgtffRPGPKnliyyGEHPLSFAACVGNEEI-VRLLIEHGADIRAQDSLGNTVLHILVL-----------QPNK 182

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370483583 275 VIDCE--------DKNGN-------------TPLHIAARYGHELLINTLITSgadtaKRGIHGMF 318
Cdd:cd22192   183 TFACQmydlilsyDKEDDlqpldlvpnnqglTPFKLAAKEGNIVMFQHLVQK-----RRHIQWTY 242

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

638-720

4.28e-06

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 50.67 E-value: 4.28e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 638 AVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQsaasMDANPATADNHGYTALHWACYNGHETCVE 717
Cdd:PTZ00322   90 AASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLE----FGADPTLLDKDGKTPLELAEENGFREVVQ 165


                  ...
gi 1370483583 718 LLL 720
Cdd:PTZ00322  166 LLS 168

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

84-115

4.57e-06

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 44.20 E-value: 4.57e-06

                          10        20        30
                  ....*....|....*....|....*....|...
gi 1370483583  84 GRTALHHAAFS-GHGEMVKLLLSRGANINAFDK 115
Cdd:pfam00023   2 GNTPLHLAAGRrGNLEIVKLLLSKGADVNARDK 34

Ank_4

Ankyrin repeats (many copies);

319-360

5.09e-06

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 44.57 E-value: 5.09e-06

                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1370483583 319 PLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGG 360
Cdd:pfam13637   4 ALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNG 45

Ank_5

Ankyrin repeats (many copies);

202-256

5.30e-06

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 44.64 E-value: 5.30e-06

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370483583 202 LIDCGAI-VNQKNEKGFTPLHFAAasTHGAL-CLELLVGNGADVNMKSKDGKTPLHM 256
Cdd:pfam13857   1 LLEHGPIdLNRLDGEGYTPLHVAA--KYGALeIVRVLLAYGVDLNLKDEEGLTALDL 55

TRPV

Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ...

52-203

5.73e-06

Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily (TRPV), named after the vanilloid receptor 1 (TRPV1), consists of six members: four thermo-sensing channels (TRPV1, TRPV2, TRPV3, and TRPV4) and two Ca2+ selective channels (TRPV5 and TRPV6). The calcium-selective channels TRPV5 and TRPV6 can be heterotetramers and are important for general Ca2+ homeostasis. All four channels within the TRPV1-4 group show temperature-invoked currents when expressed in heterologous cell systems, ranging from activation at ~25C for TRPV4 to ~52C for TRPV2. The structure of TRPV shows the typical topology features of all Transient Receptor Potential (TRP) ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains. The TRP family consists of membrane proteins that function as ion channels that communicate between the cell and its environment, by a vast array of physical or chemical stimuli, including radiation (in the form of temperature, infrared ,or light) and pressure (osmotic or mechanical). TRP channels are formed by a tetrameric complex of channel subunits. Based on sequence identity, the mammalian TRP channel family is classified into six subfamilies, with significant sequence similarity within the transmembrane domains, but very low similarity in their N- and C-terminal cytoplasmic regions. The six subfamilies are named based on their first member: TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPA (ankyrin), TRPML (mucolipin), and TRPP (polycystic).

Pssm-ID: 411975 [Multi-domain] Cd Length: 600 Bit Score: 50.26 E-value: 5.73e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  52 QTPLHIAAANKAVKCAEALVPLLSNVNVSDRA--------------GRTALHHAAFSGHGEMVKLLLSRGANINA----- 112
Cdd:cd21882    27 KTCLHKAALNLNDGVNEAIMLLLEAAPDSGNPkelvnapctdefyqGQTALHIAIENRNLNLVRLLVENGADVSAratgr 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 113 -FDKKDRRAIHW-------AAYMGHIEVVKLLVSHGAE---VTCKDKKSYTPLHA---------AASSGMISVVKYLLDL 172
Cdd:cd21882   107 fFRKSPGNLFYFgelplslAACTNQEEIVRLLLENGAQpaaLEAQDSLGNTVLHAlvlqadntpENSAFVCQMYNLLLSY 186

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1370483583 173 G------VDMNE-PNAYGNTPLHVACYNGQDVVVNELI 203
Cdd:cd21882   187 GahldptQQLEEiPNHQGLTPLKLAAVEGKIVMFQHIL 224

Ank_4

Ankyrin repeats (many copies);

252-303

7.69e-06

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 44.19 E-value: 7.69e-06

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1370483583 252 TPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLI 303
Cdd:pfam13637   3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

Ank_5

Ankyrin repeats (many copies);

37-91

9.75e-06

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 43.87 E-value: 9.75e-06

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370483583  37 LLKH-SADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHA 91
Cdd:pfam13857   1 LLEHgPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56

PHA02875

ankyrin repeat protein; Provisional

383-601

9.79e-06

ankyrin repeat protein; Provisional

Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 49.22 E-value: 9.79e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 383 RSPLHYAAANCNYQCLFALVGSGASVND-LDERGCTPLHYAaTSDTDGKCLEYLLRNDANPGIrdkqgynavhysaaygh 461
Cdd:PHA02875   69 ESELHDAVEEGDVKAVEELLDLGKFADDvFYKDGMTPLHLA-TILKKLDIMKLLIARGADPDI----------------- 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 462 rlclqliasetpldvlmetSGTDmlsdsdnraTISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVE 541
Cdd:PHA02875  131 -------------------PNTD---------KFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIA 182

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370483583 542 CVDVLINQGASIlvkDYILKRTPIHA---AATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPL 601
Cdd:PHA02875  183 ICKMLLDSGANI---DYFGKNGCVAAlcyAIENNKIDIVRLFIKRGADCNIMFMIEGEECTIL 242

TRPV

Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ...

639-813

1.00e-05

Pssm-ID: 411975 [Multi-domain] Cd Length: 600 Bit Score: 49.49 E-value: 1.00e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 639 VTGHEECVDALLQHGAKclLRDSRGRTPIHLSAACGHIGVLGA---LLQSAASMDAN------PATADNH-GYTALHWAC 708
Cdd:cd21882     4 LLGLLECLRWYLTDSAY--QRGATGKTCLHKAALNLNDGVNEAimlLLEAAPDSGNPkelvnaPCTDEFYqGQTALHIAI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 709 YNGHETCVELLLEQ----------EVFQKTEGNAF----SPLHCAVINDNEGAAEMLIDTlGASI--VNATDSKGRTPLH 772
Cdd:cd21882    82 ENRNLNLVRLLVENgadvsaratgRFFRKSPGNLFyfgeLPLSLAACTNQEEIVRLLLEN-GAQPaaLEAQDSLGNTVLH 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370483583 773 A-----------AAFTDHVecLQLLLSHNAQVNSVDS-------TGKTPLMMAAENGQT 813
Cdd:cd21882   161 AlvlqadntpenSAFVCQM--YNLLLSYGAHLDPTQQleeipnhQGLTPLKLAAVEGKI 217

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

668-808

1.31e-05

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 49.13 E-value: 1.31e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 668 HLSAACGHIGVLgALLQSAAsmdaNPATADNHGYTALHWACYNGHETCVELLLEqevfqktegnafsplhcavindnega 747
Cdd:PTZ00322   88 QLAASGDAVGAR-ILLTGGA----DPNCRDYDGRTPLHIACANGHVQVVRVLLE-------------------------- 136

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370483583 748 aemlidtLGASiVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGK-------------TPLMMAA 808
Cdd:PTZ00322  137 -------FGAD-PTLLDKDGKTPLELAEENGFREVVQLLSRHSQCHFELGANAKpdsftgkppsledSPISSHH 202

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

84-112

1.72e-05

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 42.19 E-value: 1.72e-05

                           10        20
                   ....*....|....*....|....*....
gi 1370483583   84 GRTALHHAAFSGHGEMVKLLLSRGANINA 112
Cdd:smart00248   2 GRTPLHLAAENGNLEVVKLLLDKGADINA 30

Ank_4

Ankyrin repeats (many copies);

31-71

1.88e-05

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 43.03 E-value: 1.88e-05

                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1370483583  31 LEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALV 71
Cdd:pfam13637  14 LELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

269-348

1.96e-05

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 48.74 E-value: 1.96e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 269 IIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLS---SGFDIDT- 344
Cdd:PTZ00322  101 LLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRhsqCHFELGAn 180


                  ....*.
gi 1370483583 345 --PDDF 348
Cdd:PTZ00322  181 akPDSF 186

TRPV5-6

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...

417-619

2.07e-05

Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 48.47 E-value: 2.07e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 417 TPLHYAAtSDTDGKCLEYLLR-NDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSgtdmlsdSDNRATI 495
Cdd:cd22192    19 SPLLLAA-KENDVQAIKKLLKcPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAAPELVNEPMT-------SDLYQGE 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 496 SPLHLAAYHGHhqalEVLVQSLLD--LDVRNSS----------------GRTPLDLAAFKGHVECVDVLINQGASILVKD 557
Cdd:cd22192    91 TALHIAVVNQN----LNLVRELIArgADVVSPRatgtffrpgpknliyyGEHPLSFAACVGNEEIVRLLIEHGADIRAQD 166

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370483583 558 YiLKRTPIHAAAT--NGHSECLRL-LIGNAEP---QNAVD-IQDGNGQTPLMLSVLNGHTDCVYSLLNK 619
Cdd:cd22192   167 S-LGNTVLHILVLqpNKTFACQMYdLILSYDKeddLQPLDlVPNNQGLTPFKLAAKEGNIVMFQHLVQK 234

Ank_4

Ankyrin repeats (many copies);

349-402

2.12e-05

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 42.65 E-value: 2.12e-05

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1370483583 349 GRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALV 402
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

Ank_5

Ankyrin repeats (many copies);

587-635

2.31e-05

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 42.72 E-value: 2.31e-05

                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1370483583 587 QNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALH 635
Cdd:pfam13857   6 PIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALD 54

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

56-142

2.45e-05

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 48.36 E-value: 2.45e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  56 HIAAANKAVKcAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKL 135
Cdd:PTZ00322   88 QLAASGDAVG-ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQL 166


                  ....*..
gi 1370483583 136 LVSHGAE 142
Cdd:PTZ00322  167 LSRHSQC 173

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

158-264

2.62e-05

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 47.97 E-value: 2.62e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 158 ASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALcLELLV 237
Cdd:PTZ00322   90 AASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREV-VQLLS 168

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1370483583 238 GN-------GADVNMKSKDGKTPLH----MTALHGRFS 264
Cdd:PTZ00322  169 RHsqchfelGANAKPDSFTGKPPSLedspISSHHPDFS 206

PHA02716

CPXV016; CPX019; EVM010; Provisional

233-419

3.23e-05

CPXV016; CPX019; EVM010; Provisional

Pssm-ID: 165089 [Multi-domain] Cd Length: 764 Bit Score: 47.98 E-value: 3.23e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 233 LELLVGNGADVNMKSKDGKTPLHMTALHGRFSRS--QTIIQSGAVIDCEDKNGNTPLH---IAARYGHELLINTLITSGA 307
Cdd:PHA02716  195 LEWLCNNGVNVNLQNNHLITPLHTYLITGNVCASviKKIIELGGDMDMKCVNGMSPIMtyiINIDNINPEITNIYIESLD 274

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 308 DTAKRGIHGMFPLHLAALSGFS-DCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECL--NLLLNTGADFNKKDKFGRS 384
Cdd:PHA02716  275 GNKVKNIPMILHSYITLARNIDiSVVYSFLQPGVKLHYKDSAGRTCLHQYILRHNISTDiiKLLHEYGNDLNEPDNIGNT 354

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1370483583 385 PLHYAAA--------------NCNYQCLFALVGSGASVNDLDERGCTPL 419
Cdd:PHA02716  355 VLHTYLSmlsvvnildpetdnDIRLDVIQCLISLGADITAVNCLGYTPL 403

Ank_4

Ankyrin repeats (many copies);

283-336

3.39e-05

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 42.26 E-value: 3.39e-05

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1370483583 283 GNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLL 336
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

Ank_3

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

84-112

3.84e-05

Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 41.47 E-value: 3.84e-05

                          10        20
                  ....*....|....*....|....*....
gi 1370483583  84 GRTALHHAAFSGHGEMVKLLLSRGANINA 112
Cdd:pfam13606   2 GNTPLHLAARNGRLEIVKLLLENGADINA 30

Ank_4

Ankyrin repeats (many copies);

663-720

4.13e-05

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 41.88 E-value: 4.13e-05

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1370483583 663 GRTPIHLSAACGHIGVLGALLQSAASMDAnpatADNHGYTALHWACYNGHETCVELLL 720
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLEKGADINA----VDGNGETALHFAASNGNVEVLKLLL 54

PHA03095

ankyrin-like protein; Provisional

34-112

4.73e-05

ankyrin-like protein; Provisional

Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 46.94 E-value: 4.73e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  34 VQVLLKHSADVNARDKNWQTPLHIAAA-NKAVKCAEaLVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINA 112
Cdd:PHA03095  240 VLPLLIAGISINARNRYGQTPLHYAAVfNNPRACRR-LIALGADINAVSSDGNTPLSLMVRNNNGRAVRAALAKNPSAET 318

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

494-604

4.84e-05

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 47.20 E-value: 4.84e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 494 TISPLHLAAyHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGA--SILVKDyilKRTPIHAAATN 571
Cdd:PTZ00322   83 TVELCQLAA-SGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGAdpTLLDKD---GKTPLELAEEN 158

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1370483583 572 GHSECLRLLIG----------NAEPQNAVDIQDGNGQTPLMLS 604
Cdd:PTZ00322  159 GFREVVQLLSRhsqchfelgaNAKPDSFTGKPPSLEDSPISSH 201

PLN03192

Voltage-dependent potassium channel; Provisional

753-924

4.91e-05

Voltage-dependent potassium channel; Provisional

Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 47.56 E-value: 4.91e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 753 DTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSAsAELTLQDN 832
Cdd:PLN03192  511 DLLGDNGGEHDDPNMASNLLTVASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHA-CNVHIRDA 589

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 833 SKNTALHLACSKGHETsallILEKITDRNLINATNAALQTPLHVAARNGLTMvVQELLGKGASVLAVDENGYTpALACAP 912
Cdd:PLN03192  590 NGNTALWNAISAKHHK----IFRILYHFASISDPHAAGDLLCTAAKRNDLTA-MKELLKQGLNVDSEDHQGAT-ALQVAM 663

                         170
                  ....*....|..
gi 1370483583 913 NKDVADCLALIL 924
Cdd:PLN03192  664 AEDHVDMVRLLI 675

Ank_4

Ankyrin repeats (many copies);

183-237

5.17e-05

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 41.88 E-value: 5.17e-05

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1370483583 183 GNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGAlCLELLV 237
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVE-VLKLLL 54

Ank_4

Ankyrin repeats (many copies);

218-264

5.77e-05

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 41.49 E-value: 5.77e-05

                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1370483583 218 TPLHFAAASTHGAlCLELLVGNGADVNMKSKDGKTPLHMTALHGRFS 264
Cdd:pfam13637   3 TALHAAAASGHLE-LLRLLLEKGADINAVDGNGETALHFAASNGNVE 48

PHA02946

ankyin-like protein; Provisional

334-454

6.55e-05

ankyin-like protein; Provisional

Pssm-ID: 165256 [Multi-domain] Cd Length: 446 Bit Score: 46.59 E-value: 6.55e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 334 KLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCN--YQCLFALVGSGASVND- 410
Cdd:PHA02946   57 ELLHRGYSPNETDDDGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLYYLSGTDDevIERINLLVQYGAKINNs 136

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1370483583 411 LDERGCTPLhyAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVH 454
Cdd:PHA02946  137 VDEEGCGPL--LACTDPSERVFKKIMSIGFEARIVDKFGKNHIH 178

PHA02946

ankyin-like protein; Provisional

100-305

6.66e-05

ankyin-like protein; Provisional

Pssm-ID: 165256 [Multi-domain] Cd Length: 446 Bit Score: 46.59 E-value: 6.66e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 100 VKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLH--AAASSGMISVVKYLLDLGVDMN 177
Cdd:PHA02946   55 VEELLHRGYSPNETDDDGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLYylSGTDDEVIERINLLVQYGAKIN 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 178 EP-NAYGNTPLhVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTH-GALCLELLVGNGADVNMKSKDGKTPLH 255
Cdd:PHA02946  135 NSvDEEGCGPL-LACTDPSERVFKKIMSIGFEARIVDKFGKNHIHRHLMSDNpKASTISWMMKLGISPSKPDHDGNTPLH 213

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1370483583 256 MTAlhGRFSRSQTIIQ---SGAVIDCEDKNGNTPLHIAAR-YGHELLINTLITS 305
Cdd:PHA02946  214 IVC--SKTVKNVDIINlllPSTDVNKQNKFGDSPLTLLIKtLSPAHLINKLLST 265

TRPV

Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ...

322-541

8.42e-05

Pssm-ID: 411975 [Multi-domain] Cd Length: 600 Bit Score: 46.41 E-value: 8.42e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 322 LAALSGFSDCCRKLLSSgfDIDTPDDFGRTCLHAAA---AGGNLECLNLLLNTGADFNKKDKF-----------GRSPLH 387
Cdd:cd21882     1 LEELLGLLECLRWYLTD--SAYQRGATGKTCLHKAAlnlNDGVNEAIMLLLEAAPDSGNPKELvnapctdefyqGQTALH 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 388 YAAANCNYQCLFALVGSGASVND------LDERGCT-------PLHYAATSDTDgKCLEYLLRNDANP---GIRDKQGYN 451
Cdd:cd21882    79 IAIENRNLNLVRLLVENGADVSAratgrfFRKSPGNlfyfgelPLSLAACTNQE-EIVRLLLENGAQPaalEAQDSLGNT 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 452 AVHysaayghrlCLQLIASETPLDVLMETSGTDMLsdsdnratispLHLAAYHGHHQALEvlvqslldlDVRNSSGRTPL 531
Cdd:cd21882   158 VLH---------ALVLQADNTPENSAFVCQMYNLL-----------LSYGAHLDPTQQLE---------EIPNHQGLTPL 208

                         250
                  ....*....|
gi 1370483583 532 DLAAFKGHVE 541
Cdd:cd21882   209 KLAAVEGKIV 218

PHA02798

ankyrin-like protein; Provisional

590-810

1.09e-04

ankyrin-like protein; Provisional

Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 45.98 E-value: 1.09e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 590 VDIQDGNGQTPL--MLSVL---NGHTDCVYSLLNKGANVDAKDKWGRTA----LHRGAVTgHEECVDALLQHGAKCLLRD 660
Cdd:PHA02798   64 VNGLDNEYSTPLctILSNIkdyKHMLDIVKILIENGADINKKNSDGETPlyclLSNGYIN-NLEILLFMIENGADTTLLD 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 661 SRGRTPIHLSAACGH---IGVLGALLQSAasMDANpaTADN-HGYTALHwaCYNGHE------TCVELLLEQ----EVFQ 726
Cdd:PHA02798  143 KDGFTMLQVYLQSNHhidIEIIKLLLEKG--VDIN--THNNkEKYDTLH--CYFKYNidridaDILKLFVDNgfiiNKEN 216

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 727 KTEGNAFSPLHCAVINDNEGAAEMLIDTLGASI-VNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLM 805
Cdd:PHA02798  217 KSHKKKFMEYLNSLLYDNKRFKKNILDFIFSYIdINQVDELGFNPLYYSVSHNNRKIFEYLLQLGGDINIITELGNTCLF 296


                  ....*
gi 1370483583 806 MAAEN 810
Cdd:PHA02798  297 TAFEN 301

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

583-692

1.25e-04

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 46.04 E-value: 1.25e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 583 NAEPQNAVDiqdgngQTPL-MLSV------LNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAK 655
Cdd:PTZ00322   67 NLTTEEVID------PVVAhMLTVelcqlaASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGAD 140

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1370483583 656 CLLRDSRGRTPIHLSAACGHIGVLGALL---QSAASMDAN 692
Cdd:PTZ00322  141 PTLLDKDGKTPLELAEENGFREVVQLLSrhsQCHFELGAN 180

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

766-797

1.41e-04

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 39.97 E-value: 1.41e-04

                          10        20        30
                  ....*....|....*....|....*....|...
gi 1370483583 766 KGRTPLHAAA-FTDHVECLQLLLSHNAQVNSVD 797
Cdd:pfam00023   1 DGNTPLHLAAgRRGNLEIVKLLLSKGADVNARD 33

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

321-437

1.43e-04

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 45.66 E-value: 1.43e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 321 HLAALSGFSDccrKLLSSGFDIDTPDDFGRTCLHAA-------AAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANC 393
Cdd:PTZ00322   50 HLEALEATEN---KDATPDHNLTTEEVIDPVVAHMLtvelcqlAASGDAVGARILLTGGADPNCRDYDGRTPLHIACANG 126

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1370483583 394 NYQCLFALVGSGASVNDLDERGCTPLHYAATSDTdGKCLEYLLR 437
Cdd:PTZ00322  127 HVQVVRVLLEFGADPTLLDKDGKTPLELAEENGF-REVVQLLSR 169

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

808-903

1.70e-04

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 45.66 E-value: 1.70e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 808 AENGQTNTVEMLVSSAsAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNaalQTPLHVAARNGLTMVVQ 887
Cdd:PTZ00322   90 AASGDAVGARILLTGG-ADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDG---KTPLELAEENGFREVVQ 165

                          90
                  ....*....|....*.
gi 1370483583 888 ELLGKGASVLAVDENG 903
Cdd:PTZ00322  166 LLSRHSQCHFELGANA 181

Ank_5

Ankyrin repeats (many copies);

169-223

2.92e-04

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 39.64 E-value: 2.92e-04

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370483583 169 LLDLG-VDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFA 223
Cdd:pfam13857   1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56

Ank_5

Ankyrin repeats (many copies);

756-807

3.16e-04

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 39.64 E-value: 3.16e-04

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1370483583 756 GASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMA 807
Cdd:pfam13857   5 GPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56

Ank_5

Ankyrin repeats (many copies);

484-534

3.19e-04

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 39.64 E-value: 3.19e-04

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1370483583 484 DMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLA 534
Cdd:pfam13857   6 PIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

596-628

3.31e-04

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 38.81 E-value: 3.31e-04

                          10        20        30
                  ....*....|....*....|....*....|....
gi 1370483583 596 NGQTPLMLSVL-NGHTDCVYSLLNKGANVDAKDK 628
Cdd:pfam00023   1 DGNTPLHLAAGrRGNLEIVKLLLSKGADVNARDK 34

PHA02989

ankyrin repeat protein; Provisional

98-229

3.48e-04

ankyrin repeat protein; Provisional

Pssm-ID: 222954 [Multi-domain] Cd Length: 494 Bit Score: 44.35 E-value: 3.48e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  98 EMVKLLLSRGANINAFDKKDRRAI------HWAAYMGHIEVVKLLVSHgAEVTCKDKKSYTPLHAAASSGMISVVKYLLD 171
Cdd:PHA02989  199 KVIKYLIKKGVNIETNNNGSESVLesfldnNKILSKKEFKVLNFILKY-IKINKKDKKGFNPLLISAKVDNYEAFNYLLK 277

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1370483583 172 LGVDMNEPNAYGNTPLHVACYNGQDVVVNElidcgaIVNQKNEKGFTPLHFAAASTHG 229
Cdd:PHA02989  278 LGDDIYNVSKDGDTVLTYAIKHGNIDMLNR------ILQLKPGKYLIKKTFEYFSEHG 329

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

151-178

3.53e-04

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 38.72 E-value: 3.53e-04

                           10        20
                   ....*....|....*....|....*...
gi 1370483583  151 YTPLHAAASSGMISVVKYLLDLGVDMNE 178
Cdd:smart00248   3 RTPLHLAAENGNLEVVKLLLDKGADINA 30

Ank_5

Ankyrin repeats (many copies);

103-157

4.13e-04

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 39.25 E-value: 4.13e-04

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370483583 103 LLSRG-ANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAA 157
Cdd:pfam13857   1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

414-447

4.44e-04

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 38.42 E-value: 4.44e-04

                          10        20        30
                  ....*....|....*....|....*....|....
gi 1370483583 414 RGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDK 447
Cdd:pfam00023   1 DGNTPLHLAAGRRGNLEIVKLLLSKGADVNARDK 34

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

321-415

4.65e-04

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 44.12 E-value: 4.65e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 321 HLAAlSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFA 400
Cdd:PTZ00322   88 QLAA-SGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQL 166

                          90
                  ....*....|....*
gi 1370483583 401 LVGSGASVNDLDERG 415
Cdd:PTZ00322  167 LSRHSQCHFELGANA 181

TRPV3

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 3; TRPV3 is a ...

178-294

4.78e-04

Pssm-ID: 411978 [Multi-domain] Cd Length: 680 Bit Score: 43.98 E-value: 4.78e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 178 EPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQK----------NEKGF----TPLHFAAASTHGALcLELLVGNGAD- 242
Cdd:cd22194   136 EEAYEGQTALNIAIERRQGDIVKLLIAKGADVNAHakgvffnpkyKHEGFyfgeTPLALAACTNQPEI-VQLLMEKESTd 214

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370483583 243 VNMKSKDGKTPLHMTALHGRFSRSQT--IIQSGAVI--DCEDKN--------GNTPLHIAARYG 294
Cdd:cd22194   215 ITSQDSRGNTVLHALVTVAEDSKTQNdfVKRMYDMIllKSENKNletirnneGLTPLQLAAKMG 278

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

766-794

5.12e-04

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 38.34 E-value: 5.12e-04

                           10        20
                   ....*....|....*....|....*....
gi 1370483583  766 KGRTPLHAAAFTDHVECLQLLLSHNAQVN 794
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLDKGADIN 29

PHA02859

ankyrin repeat protein; Provisional

372-454

5.16e-04

ankyrin repeat protein; Provisional

Pssm-ID: 165195 [Multi-domain] Cd Length: 209 Bit Score: 42.50 E-value: 5.16e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 372 GADFNKKDK-FGRSPLHYAAA---NCNYQCLFALVGSGASVNDLDERGCTPLH-YAATSDTDGKCLEYLLRNDANPGIRD 446
Cdd:PHA02859   76 GADVNFKTRdNNLSALHHYLSfnkNVEPEILKILIDSGSSITEEDEDGKNLLHmYMCNFNVRINVIKLLIDSGVSFLNKD 155


                  ....*...
gi 1370483583 447 KQGYNAVH 454
Cdd:PHA02859  156 FDNNNILY 163

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

182-210

6.48e-04

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 37.95 E-value: 6.48e-04

                           10        20
                   ....*....|....*....|....*....
gi 1370483583  182 YGNTPLHVACYNGQDVVVNELIDCGAIVN 210
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLDKGADIN 29

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

215-248

8.01e-04

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 37.65 E-value: 8.01e-04

                          10        20        30
                  ....*....|....*....|....*....|....
gi 1370483583 215 KGFTPLHFAAASTHGALCLELLVGNGADVNMKSK 248
Cdd:pfam00023   1 DGNTPLHLAAGRRGNLEIVKLLLSKGADVNARDK 34

TRPV3

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 3; TRPV3 is a ...

84-224

8.18e-04

Pssm-ID: 411978 [Multi-domain] Cd Length: 680 Bit Score: 43.21 E-value: 8.18e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  84 GRTALHHAAFSGHGEMVKLLLSRGANINA------FDKKDRraiHWAAYMGHievvkllvshgaevtckdkksyTPLHAA 157
Cdd:cd22194   141 GQTALNIAIERRQGDIVKLLIAKGADVNAhakgvfFNPKYK---HEGFYFGE----------------------TPLALA 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 158 ASSGMISVVKYLLDlgvdmNEPNAY------GNTPLH----VA-CYNGQDVVVNELID-----CG--AIVNQKNEKGFTP 219
Cdd:cd22194   196 ACTNQPEIVQLLME-----KESTDItsqdsrGNTVLHalvtVAeDSKTQNDFVKRMYDmillkSEnkNLETIRNNEGLTP 270


                  ....*
gi 1370483583 220 LHFAA 224
Cdd:cd22194   271 LQLAA 275

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

182-214

9.94e-04

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 37.65 E-value: 9.94e-04

                          10        20        30
                  ....*....|....*....|....*....|....
gi 1370483583 182 YGNTPLHVACY-NGQDVVVNELIDCGAIVNQKNE 214
Cdd:pfam00023   1 DGNTPLHLAAGrRGNLEIVKLLLSKGADVNARDK 34

TRPV

Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ...

562-668

1.02e-03

Pssm-ID: 411975 [Multi-domain] Cd Length: 600 Bit Score: 42.94 E-value: 1.02e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 562 RTPIHAAATN---GHSECLRLLIgNAEPQNAVDIQDGN---------GQTPLMLSVLNGHTDCVYSLLNKGANVDAK--- 626
Cdd:cd21882    27 KTCLHKAALNlndGVNEAIMLLL-EAAPDSGNPKELVNapctdefyqGQTALHIAIENRNLNLVRLLVENGADVSARatg 105

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1370483583 627 ---DKWGRTALHRG-------AVTGHEECVDALLQHGAK---CLLRDSRGRTPIH 668
Cdd:cd21882   106 rffRKSPGNLFYFGelplslaACTNQEEIVRLLLENGAQpaaLEAQDSLGNTVLH 160

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

282-308

1.04e-03

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 37.18 E-value: 1.04e-03

                           10        20
                   ....*....|....*....|....*..
gi 1370483583  282 NGNTPLHIAARYGHELLINTLITSGAD 308
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLDKGAD 27

PHA02716

CPXV016; CPX019; EVM010; Provisional

98-320

1.05e-03

CPXV016; CPX019; EVM010; Provisional

Pssm-ID: 165089 [Multi-domain] Cd Length: 764 Bit Score: 42.98 E-value: 1.05e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  98 EMVKLLLSRG-ANINAFDKKDRRAIhWAAYMGH----IEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMI--SVVKYLL 170
Cdd:PHA02716  156 DLIKYMVDVGiVNLNYVCKKTGYGI-LHAYLGNmyvdIDILEWLCNNGVNVNLQNNHLITPLHTYLITGNVcaSVIKKII 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 171 DLGVDMNEPNAYGNTPLHVACYNGQDV---VVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKS 247
Cdd:PHA02716  235 ELGGDMDMKCVNGMSPIMTYIINIDNInpeITNIYIESLDGNKVKNIPMILHSYITLARNIDISVVYSFLQPGVKLHYKD 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 248 KDGKTPLHMTALHGRFSRS--QTIIQSGAVIDCEDKNGNTPLH-------IAARYGHEL-------LINTLITSGADTAK 311
Cdd:PHA02716  315 SAGRTCLHQYILRHNISTDiiKLLHEYGNDLNEPDNIGNTVLHtylsmlsVVNILDPETdndirldVIQCLISLGADITA 394


                  ....*....
gi 1370483583 312 RGIHGMFPL 320
Cdd:PHA02716  395 VNCLGYTPL 403

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

699-721

1.20e-03

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 37.18 E-value: 1.20e-03

                           10        20
                   ....*....|....*....|...
gi 1370483583  699 HGYTALHWACYNGHETCVELLLE 721
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLD 23

PHA02798

ankyrin-like protein; Provisional

749-864

1.22e-03

ankyrin-like protein; Provisional

Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 42.51 E-value: 1.22e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 749 EMLIDtLGASiVNATDSKGRTPL-----HAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVS-- 821
Cdd:PHA02798   55 KLFIN-LGAN-VNGLDNEYSTPLctilsNIKDYKHMLDIVKILIENGADINKKNSDGETPLYCLLSNGYINNLEILLFmi 132

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1370483583 822 SASAELTLQDNSKNTALHLACSKGHETSALLI---LEKITDRNLIN 864
Cdd:PHA02798  133 ENGADTTLLDKDGFTMLQVYLQSNHHIDIEIIkllLEKGVDINTHN 178

Ank_5

Ankyrin repeats (many copies);

373-422

1.25e-03

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 37.71 E-value: 1.25e-03

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1370483583 373 ADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYA 422
Cdd:pfam13857   7 IDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56

PHA02736

Viral ankyrin protein; Provisional

81-191

1.32e-03

Viral ankyrin protein; Provisional

Pssm-ID: 165103 [Multi-domain] Cd Length: 154 Bit Score: 40.24 E-value: 1.32e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  81 DRAGRTALHHaaFSGHGEMVKLLLSRGANINA-------FDKKDRRAIHWAAYMGHI---EVVKLLVSHGAEVTCKDKK- 149
Cdd:PHA02736   14 DIEGENILHY--LCRNGGVTDLLAFKNAISDEnrylvleYNRHGKQCVHIVSNPDKAdpqEKLKLLMEWGADINGKERVf 91

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1370483583 150 SYTPLHAAASSGMISVVKYLLDL-GVDMNEPNAYGNTPLHVAC 191
Cdd:PHA02736   92 GNTPLHIAVYTQNYELATWLCNQpGVNMEILNYAFKTPYYVAC 134

PHA02716

CPXV016; CPX019; EVM010; Provisional

81-205

1.48e-03

CPXV016; CPX019; EVM010; Provisional

Pssm-ID: 165089 [Multi-domain] Cd Length: 764 Bit Score: 42.59 E-value: 1.48e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  81 DRAGRTALHHAAFSGH--GEMVKLLLSRGANINAFDKKDRRAIHwaAYMGHIEVVKLLVSHgaevTCKDKKsytplhaaa 158
Cdd:PHA02716  314 DSAGRTCLHQYILRHNisTDIIKLLHEYGNDLNEPDNIGNTVLH--TYLSMLSVVNILDPE----TDNDIR--------- 378

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1370483583 159 ssgmISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDC 205
Cdd:PHA02716  379 ----LDVIQCLISLGADITAVNCLGYTPLTSYICTAQNYMYYDIIDC 421

TRPV3

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 3; TRPV3 is a ...

562-668

1.55e-03

Pssm-ID: 411978 [Multi-domain] Cd Length: 680 Bit Score: 42.44 E-value: 1.55e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 562 RTPIHAAATNGhseCLRLLIgNAEPQNavdiQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDK------------- 628
Cdd:cd22194   114 RILLAFAEENG---ILDRFI-NAEYTE----EAYEGQTALNIAIERRQGDIVKLLIAKGADVNAHAKgvffnpkykhegf 185

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1370483583 629 -WGRTALHRGAVTGHEECVDALLQHGAKCL-LRDSRGRTPIH 668
Cdd:cd22194   186 yFGETPLALAACTNQPEIVQLLMEKESTDItSQDSRGNTVLH 227

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

120-145

1.75e-03

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 36.80 E-value: 1.75e-03

                           10        20
                   ....*....|....*....|....*.
gi 1370483583  120 AIHWAAYMGHIEVVKLLVSHGAEVTC 145
Cdd:smart00248   5 PLHLAAENGNLEVVKLLLDKGADINA 30

Ank_4

Ankyrin repeats (many copies);

835-890

1.86e-03

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 37.25 E-value: 1.86e-03

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370483583 835 NTALHLACSKGHETSALLILEKITDrnlINATNAALQTPLHVAARNGLTMVVQELL 890
Cdd:pfam13637   2 LTALHAAAASGHLELLRLLLEKGAD---INAVDGNGETALHFAASNGNVEVLKLLL 54

Ank_5

Ankyrin repeats (many copies);

616-669

1.97e-03

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 37.33 E-value: 1.97e-03

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1370483583 616 LLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHL 669
Cdd:pfam13857   2 LEHGPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDL 55

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

120-148

2.02e-03

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 36.50 E-value: 2.02e-03

                          10        20        30
                  ....*....|....*....|....*....|
gi 1370483583 120 AIHWAAYM-GHIEVVKLLVSHGAEVTCKDK 148
Cdd:pfam00023   5 PLHLAAGRrGNLEIVKLLLSKGADVNARDK 34

Ank_5

Ankyrin repeats (many copies);

861-906

2.40e-03

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 36.94 E-value: 2.40e-03

                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1370483583 861 NLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTP 906
Cdd:pfam13857   7 IDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTA 52

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

527-553

2.52e-03

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 36.41 E-value: 2.52e-03

                           10        20
                   ....*....|....*....|....*..
gi 1370483583  527 GRTPLDLAAFKGHVECVDVLINQGASI 553
Cdd:smart00248   2 GRTPLHLAAENGNLEVVKLLLDKGADI 28

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

527-557

2.53e-03

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 36.50 E-value: 2.53e-03

                          10        20        30
                  ....*....|....*....|....*....|..
gi 1370483583 527 GRTPLDLAAFK-GHVECVDVLINQGASILVKD 557
Cdd:pfam00023   2 GNTPLHLAAGRrGNLEIVKLLLSKGADVNARD 33

TRPV1

cd22196

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 1; Vanilloid receptor 1 ...

116-226

2.55e-03

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 1; Vanilloid receptor 1 (TRPV1), a capsaicin (vanilloid) receptor, is the founding member of the vanilloid TRP subfamily (TRPV). In humans, it is expressed in the brain, kidney, pancreas, testis, uterus, spleen, stomach, small intestine, lung and liver. TRPV1 has been implicated to have function in thermo-sensation (heat), autonomic thermoregulation, nociception, food intake regulation, and multiple functions in the gastrointestinal (GI) tract. The receptor has also been involved in growth cone guidance, long-term depression, endocannabinoid signaling and osmosensing in the central nervous system. TRPV1 is up regulated in several human pathological conditions including vulvodynia, GI inflammation, Crohn's disease and ulcerative colitis. TRPV1 knock-out mice exhibit impaired sensation to thermal-mechanical acute pain. The structure of TRPV shows the typical topology features of all Transient Receptor Potential (TRP) ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains.

Pssm-ID: 411980 [Multi-domain] Cd Length: 649 Bit Score: 41.72 E-value: 2.55e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 116 KDRRAIHWAAYMGHIEVVKLLVSHGAEVTC-------KDKKSYT-------PLHAAASSGMISVVKYLLD---LGVDMNE 178
Cdd:cd22196    93 KGQTALHIAIERRNMHLVELLVQNGADVHArasgeffKKKKGGPgfyfgelPLSLAACTNQLDIVKFLLEnphSPADISA 172

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370483583 179 PNAYGNTPLHVACYNGQDVVVN---------ELIDCGAIVNQK-------NEKGFTPLHFAAAS 226
Cdd:cd22196   173 RDSMGNTVLHALVEVADNTPENtkfvtkmynEILILGAKIRPLlkleeitNKKGLTPLKLAAKT 236

PHA02989

ankyrin repeat protein; Provisional

163-422

2.88e-03

ankyrin repeat protein; Provisional

Pssm-ID: 222954 [Multi-domain] Cd Length: 494 Bit Score: 41.27 E-value: 2.88e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 163 ISVVKYLLDLGVDMNEpnAYGNTPLHVACYNGQDV---VVNELIDCGAIVNQKnekGF--TPL-----HFAAASTHGALC 232
Cdd:PHA02989   16 KNALEFLLRTGFDVNE--EYRGNSILLLYLKRKDVkikIVKLLIDNGADVNYK---GYieTPLcavlrNREITSNKIKKI 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 233 LELLVGNGADVNMKSKDGKTPLhMTALHG---------RFsrsqtIIQSGA-VIDCEDKNGNTPLHIaarYGHELLINT- 301
Cdd:PHA02989   91 VKLLLKFGADINLKTFNGVSPI-VCFIYNsninncdmlRF-----LLSKGInVNDVKNSRGYNLLHM---YLESFSVKKd 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 302 ----LITSGADT-AKRGIHGMFPLHLAALSGFS----DCCRKLLSSGFDIDTPDDFGRTCLHAAAagGNLECLNLLLNTG 372
Cdd:PHA02989  162 vikiLLSFGVNLfEKTSLYGLTPMNIYLRNDIDvisiKVIKYLIKKGVNIETNNNGSESVLESFL--DNNKILSKKEFKV 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370483583 373 ADF-------NKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYA 422
Cdd:PHA02989  240 LNFilkyikiNKKDKKGFNPLLISAKVDNYEAFNYLLKLGDDIYNVSKDGDTVLTYA 296

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

288-360

2.88e-03

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 41.42 E-value: 2.88e-03

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370483583 288 HIAARyGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGG 360
Cdd:PTZ00322   88 QLAAS-GDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENG 159

Ank_5

Ankyrin repeats (many copies);

76-115

2.93e-03

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 36.94 E-value: 2.93e-03

                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1370483583  76 NVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDK 115
Cdd:pfam13857   8 DLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDE 47

Ank_5

Ankyrin repeats (many copies);

406-455

2.93e-03

Ankyrin repeats (many copies);

Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 36.94 E-value: 2.93e-03

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1370483583 406 ASVNDLDERGCTPLHYAAtSDTDGKCLEYLLRNDANPGIRDKQGYNAVHY 455
Cdd:pfam13857   7 IDLNRLDGEGYTPLHVAA-KYGALEIVRVLLAYGVDLNLKDEEGLTALDL 55

TRPV1

cd22196

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 1; Vanilloid receptor 1 ...

760-892

3.50e-03

Pssm-ID: 411980 [Multi-domain] Cd Length: 649 Bit Score: 41.33 E-value: 3.50e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 760 VNA--TDS--KGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDST--------------GKTPLMMAAENGQTNTVEMLVS 821
Cdd:cd22196    83 VNAayTDSyyKGQTALHIAIERRNMHLVELLVQNGADVHARASGeffkkkkggpgfyfGELPLSLAACTNQLDIVKFLLE 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 822 S--ASAELTLQDNSKNTALHLACS---------------------KGHETSALLILEKITDRNLInatnaalqTPLHVAA 878
Cdd:cd22196   163 NphSPADISARDSMGNTVLHALVEvadntpentkfvtkmyneiliLGAKIRPLLKLEEITNKKGL--------TPLKLAA 234

                         170
                  ....*....|....
gi 1370483583 879 RNGLTMVVQELLGK 892
Cdd:cd22196   235 KTGKIGIFAYILGR 248

ANK

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...

596-625

3.77e-03

Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 35.64 E-value: 3.77e-03

                           10        20        30
                   ....*....|....*....|....*....|
gi 1370483583  596 NGQTPLMLSVLNGHTDCVYSLLNKGANVDA 625
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30

trp

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ...

335-515

4.20e-03

Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 41.22 E-value: 4.20e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 335 LLSSGFDIDTpddfGRTCLHAA-----------------AAGGNLECLNLLLNTGADFNkkdkFGRSPLHYAAANCNYQC 397
Cdd:TIGR00870  72 LLNLSCRGAV----GDTLLHAIsleyvdaveaillhllaAFRKSGPLELANDQYTSEFT----PGITALHLAAHRQNYEI 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 398 LFALVGSGASVN--------------DLDERGCTPLH-YAATSDTDgkCLEYLLRNDANPGIRDKQGYNAVH-------Y 455
Cdd:TIGR00870 144 VKLLLERGASVParacgdffvksqgvDSFYHGESPLNaAACLGSPS--IVALLSEDPADILTADSLGNTLLHllvmeneF 221

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370483583 456 SAAYGH--RLCLQLIasetpLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQ 515
Cdd:TIGR00870 222 KAEYEElsCQMYNFA-----LSLLDKLRDSKELEVILNHQGLTPLKLAAKEGRIVLFRLKLA 278

TRPV2

cd22197

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 2; TRPV2 is closely ...

759-881

4.35e-03

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 2; TRPV2 is closely related to TRPV1, sharing high sequence identity (>50%), but TRPV2 shows a higher temperature threshold and sensitivity for activation than TRPV1. TRPV2 can be stimulated by ligands or lipids, and is involved in osmosensation and mechanosensation. TRPV2 is expressed in both neuronal and non-neuronal tissues, and it has been implicated in diverse physiological and pathophysiological processes, including cardiac-structure maintenance, innate immunity, and cancer. TRPV2 belongs to the vanilloid TRP subfamily (TRPV), named after the founding member vanilloid receptor 1 (TRPV1). The structure of TRPV shows the typical topology features of all Transient Receptor Potential (TRP) ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains.

Pssm-ID: 411981 [Multi-domain] Cd Length: 640 Bit Score: 40.99 E-value: 4.35e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 759 IVNA--TDS--KGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDST-------------GKTPLMMAAENGQTNTVEMLVS 821
Cdd:cd22197    82 LVNAqcTDEyyRGHSALHIAIEKRSLQCVKLLVENGADVHARACGrffqkkqgtcfyfGELPLSLAACTKQWDVVNYLLE 161

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370483583 822 SAS--AELTLQDNSKNTALH---LACSKGHETSALL------ILEKITDRN----LINATNAALQTPLHVAARNG 881
Cdd:cd22197   162 NPHqpASLQAQDSLGNTVLHalvMIADNSPENSALVikmydgLLQAGARLCptvqLEEISNHEGLTPLKLAAKEG 236

Ank_4

Ankyrin repeats (many copies);

872-923

4.51e-03

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 36.10 E-value: 4.51e-03

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1370483583 872 TPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALI 923
Cdd:pfam13637   3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54

PHA02859

ankyrin repeat protein; Provisional

734-839

4.86e-03

ankyrin repeat protein; Provisional

Pssm-ID: 165195 [Multi-domain] Cd Length: 209 Bit Score: 39.42 E-value: 4.86e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 734 SPLHCAVIND--NEGAAEMLIDTlGASIVNATDSKGRTPLHA-AAFTDHV--ECLQLLLSHNAQVNSVDSTGKTPLMMAA 808
Cdd:PHA02859   53 TPIFSCLEKDkvNVEILKFLIEN-GADVNFKTRDNNLSALHHyLSFNKNVepEILKILIDSGSSITEEDEDGKNLLHMYM 131

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1370483583 809 ENGQTN--TVEMLVSSASAELTlQDNSKNTALH 839
Cdd:PHA02859  132 CNFNVRinVIKLLIDSGVSFLN-KDFDNNNILY 163

PHA02791

ankyrin-like protein; Provisional

696-865

5.46e-03

ankyrin-like protein; Provisional

Pssm-ID: 165154 [Multi-domain] Cd Length: 284 Bit Score: 40.03 E-value: 5.46e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 696 ADNHGYTALHWACYNGHETCVELLLEQEVFQKTEGNAFsPLH-CAVINDNEGAAEMLIDTLGASivnATDSKGRTPLHAA 774
Cdd:PHA02791   26 ADVHGHSALYYAIADNNVRLVCTLLNAGALKNLLENEF-PLHqAATLEDTKIVKILLFSGMDDS---QFDDKGNTALYYA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 775 AFTDHVECLQLLLSHNAQVNSVDSTG-KTPLMMAAENGQTNTVEMLVSSASAELTLQdnSKNTALHLACSKGHETSALLI 853
Cdd:PHA02791  102 VDSGNMQTVKLFVKKNWRLMFYGKTGwKTSFYHAVMLNDVSIVSYFLSEIPSTFDLA--ILLSCIHITIKNGHVDMMILL 179

                         170
                  ....*....|..
gi 1370483583 854 LEKITDRNLINA 865
Cdd:PHA02791  180 LDYMTSTNTNNS 191

Ank_4

Ankyrin repeats (many copies);

802-847

5.72e-03

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 36.10 E-value: 5.72e-03

                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1370483583 802 TPLMMAAENGQTNTVEMLVSSaSAELTLQDNSKNTALHLACSKGHE 847
Cdd:pfam13637   3 TALHAAAASGHLELLRLLLEK-GADINAVDGNGETALHFAASNGNV 47

Ank_3

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

182-210

5.87e-03

Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 35.31 E-value: 5.87e-03

                          10        20
                  ....*....|....*....|....*....
gi 1370483583 182 YGNTPLHVACYNGQDVVVNELIDCGAIVN 210
Cdd:pfam13606   1 DGNTPLHLAARNGRLEIVKLLLENGADIN 29

Ank_3

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

282-308

6.81e-03

Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 34.93 E-value: 6.81e-03

                          10        20
                  ....*....|....*....|....*..
gi 1370483583 282 NGNTPLHIAARYGHELLINTLITSGAD 308
Cdd:pfam13606   1 DGNTPLHLAARNGRLEIVKLLLENGAD 27

PHA02884

ankyrin repeat protein; Provisional

165-259

7.09e-03

ankyrin repeat protein; Provisional

Pssm-ID: 165212 [Multi-domain] Cd Length: 300 Bit Score: 39.58 E-value: 7.09e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 165 VVKYLLDLGVDMNEP-----NAYgNTPLHVACYNGQDVVVNELIDCGAIVNQ-KNEKGFTPLHFAAasTHGAL-CLELLV 237
Cdd:PHA02884   48 IIDAILKLGADPEAPfplseNSK-TNPLIYAIDCDNDDAAKLLIRYGADVNRyAEEAKITPLYISV--LHGCLkCLEILL 124

                          90       100
                  ....*....|....*....|..
gi 1370483583 238 GNGADVNMKSKDGKTPLHMTAL 259
Cdd:PHA02884  125 SYGADINIQTNDMVTPIELALM 146

Ank

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...

282-308

7.86e-03

Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 34.96 E-value: 7.86e-03

                          10        20
                  ....*....|....*....|....*...
gi 1370483583 282 NGNTPLHIAA-RYGHELLINTLITSGAD 308
Cdd:pfam00023   1 DGNTPLHLAAgRRGNLEIVKLLLSKGAD 28

Ank_4

Ankyrin repeats (many copies);

417-467

8.32e-03

Ankyrin repeats (many copies);

Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 35.33 E-value: 8.32e-03

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1370483583 417 TPLHYAATSDtDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQL 467
Cdd:pfam13637   3 TALHAAAASG-HLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKL 52

trp

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ...

710-890

8.81e-03

Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 40.06 E-value: 8.81e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 710 NGHETCVELLLEQEVFQKTEGNAfspLHCAVINDnEGAAEMLI--------DTLGASIVNATD----SKGRTPLHAAAFT 777
Cdd:TIGR00870  63 NENLELTELLLNLSCRGAVGDTL---LHAISLEY-VDAVEAILlhllaafrKSGPLELANDQYtsefTPGITALHLAAHR 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 778 DHVECLQLLLSHNAQVNS------------VDST--GKTPLMMAAENGQTNTVEMLvSSASAELTLQDNSKNTALHL--- 840
Cdd:TIGR00870 139 QNYEIVKLLLERGASVPAracgdffvksqgVDSFyhGESPLNAAACLGSPSIVALL-SEDPADILTADSLGNTLLHLlvm 217

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 841 ---------ACSKGHETSALLILEKITD-RNLINATNAALQTPLHVAARNGLTMVVQELL 890
Cdd:TIGR00870 218 enefkaeyeELSCQMYNFALSLLDKLRDsKELEVILNHQGLTPLKLAAKEGRIVLFRLKL 277

PTZ00322

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

463-546

8.96e-03

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 39.88 E-value: 8.96e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 463 LClQLIASETPLDV-LMETSGTDMLS-DSDNRatiSPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHV 540
Cdd:PTZ00322   86 LC-QLAASGDAVGArILLTGGADPNCrDYDGR---TPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFR 161


                  ....*.
gi 1370483583 541 ECVDVL 546
Cdd:PTZ00322  162 EVVQLL 167

PHA02736

Viral ankyrin protein; Provisional

178-307

9.34e-03

Viral ankyrin protein; Provisional

Pssm-ID: 165103 [Multi-domain] Cd Length: 154 Bit Score: 37.93 E-value: 9.34e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 178 EPNAYGNTPLHVACYNGqDVV-----VNELIDCGA-IVNQKNEKGFTPLHFAAAS--THGALCLELLVGNGADVNMK-SK 248
Cdd:PHA02736   12 EPDIEGENILHYLCRNG-GVTdllafKNAISDENRyLVLEYNRHGKQCVHIVSNPdkADPQEKLKLLMEWGADINGKeRV 90

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 249 DGKTPLHMTALHGRFSRSQTII-QSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGA 307
Cdd:PHA02736   91 FGNTPLHIAVYTQNYELATWLCnQPGVNMEILNYAFKTPYYVACERHDAKMMNILRAKGA 150

PHA02716

CPXV016; CPX019; EVM010; Provisional

510-704

9.36e-03

CPXV016; CPX019; EVM010; Provisional

Pssm-ID: 165089 [Multi-domain] Cd Length: 764 Bit Score: 39.90 E-value: 9.36e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 510 LEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVeCVDVL---INQGASILVKdYILKRTPIHAAATNghseclrllIGNAEP 586
Cdd:PHA02716  195 LEWLCNNGVNVNLQNNHLITPLHTYLITGNV-CASVIkkiIELGGDMDMK-CVNGMSPIMTYIIN---------IDNINP 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 587 Q--NA-VDIQDGNGQT--PLMLSVL-----NGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGH--EECVDALLQHGA 654
Cdd:PHA02716  264 EitNIyIESLDGNKVKniPMILHSYitlarNIDISVVYSFLQPGVKLHYKDSAGRTCLHQYILRHNisTDIIKLLHEYGN 343

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370483583 655 KCLLRDSRGRTPIH--LSAACG------------HIGVLGALLQSAASMDAnpatADNHGYTAL 704
Cdd:PHA02716  344 DLNEPDNIGNTVLHtyLSMLSVvnildpetdndiRLDVIQCLISLGADITA----VNCLGYTPL 403

PHA02791

ankyrin-like protein; Provisional

41-219

9.43e-03

ankyrin-like protein; Provisional

Pssm-ID: 165154 [Multi-domain] Cd Length: 284 Bit Score: 39.25 E-value: 9.43e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583  41 SADVNARDKNWQTPLHIAAANKAVKC------AEALVPLLSNvnvsdragRTALHHAAFSGHGEMVKLLLSRGANINAFD 114
Cdd:PHA02791   20 SKDAFKADVHGHSALYYAIADNNVRLvctllnAGALKNLLEN--------EFPLHQAATLEDTKIVKILLFSGMDDSQFD 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370483583 115 KKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSY-TPLHAAASSGMISVVKYLL-------DLGVDMnepnaygnTP 186
Cdd:PHA02791   92 DKGNTALYYAVDSGNMQTVKLFVKKNWRLMFYGKTGWkTSFYHAVMLNDVSIVSYFLseipstfDLAILL--------SC 163

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1370483583 187 LHVACYNGQDVVVNELIDCGAIVNQKNEKGFTP 219
Cdd:PHA02791  164 IHITIKNGHVDMMILLLDYMTSTNTNNSLLFIP 196

Ank_3