|
Name |
Accession |
Description |
Interval |
E-value |
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
21-384 |
1.61e-59 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 197.32 E-value: 1.61e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 21 LHPIIPSPVINGYRNKSTFSVnrGPDGNPKTVGFYlgtwrdgnvvcvqsnhlknipEKHSqvaqyYEVFlrqsPLEPCLV 100
Cdd:COG2265 109 VEPIIGSPEPWGYRNRARLSV--RRTDGRLRLGFY---------------------ARGS-----HELV----DIDECPL 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 101 FHEggywreltvrtnsqgHTMAIItfhpqklsqeelhvqkEIVKEFFIRGPGAACGLTSLyfqestMTRCshqqspyqll 180
Cdd:COG2265 157 LDP---------------ALNALL----------------PALRELLAELGARRGELRHL------VVRA---------- 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 181 fGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQAV 260
Cdd:COG2265 190 -GRDYLTERLGGLTFRISPGSFFQVNPEQAEALYAAALEWLDLTGGERVLDLYCGVGTFALPLARRAKKVIGVEIVPEAV 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 261 EDARWTAAFNGITNSEFHTGQAEKILPGLLKSKE-DgqsiVAVVNPARAGLHYKVIQAIRNFRAiHTLVFVSCklhgest 339
Cdd:COG2265 269 EDARENARLNGLKNVEFVAGDLEEVLPELLWGGRpD----VVVLDPPRAGAGPEVLEALAALGP-RRIVYVSC------- 336
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 1034675346 340 rnvielccppDPA------KKLLGEPFVLQQAVPVDLFPHTPHCELVLLFT 384
Cdd:COG2265 337 ----------NPAtlardlALLVEGGYRLEKVQPVDMFPHTHHVESVALLE 377
|
|
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
15-378 |
8.33e-31 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 121.85 E-value: 8.33e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 15 ERLSCL-LHPIIPSPVIN----GYRNKSTFSVNRGPDGNPKtVGFY-LGTWR--DGNVVCVQSNHL-------KNIPEKH 79
Cdd:TIGR00479 90 ERIGKFvSEPIEDVPTIGddpwGYRNKARLSLGRSPSGQLQ-AGFYqKGSHDivDVKQCPVQAPALnallpkvRAILENF 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 80 SQVAQYYEVflrqsplepclvfhEGGYWRELTVRTNSQGHTMAI--ITFHpqklsqEELHVQKEIVKEFFIRGP--GAAC 155
Cdd:TIGR00479 169 GASRYLEHK--------------ELGQARHGVLRIGRHTGELSSvdRTAL------ERFPHKEELDLYLQPDSPdvKSIC 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 156 -----GLTSLYFQESTMTrcshqqspyqlLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILL 230
Cdd:TIGR00479 229 qninpEKTNVIFGEETEV-----------IAGEMPIYDKSGDLSFTFSARDFIQVNSGQNEKLVDRALEWLELQGEERVL 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 231 DICCGTGVIGLSLAQHTSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPgllKSKEDGQSI-VAVVNPARAG 309
Cdd:TIGR00479 298 DAYCGMGTFTLPLAKQAKSVVGVEGVPESVEKAQQNAELNGIANVTFYHGTLETVLP---KQPWAGNGFdKVLLDPPRKG 374
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034675346 310 LHYKVIQAIRNFRAIHtLVFVSCKlhgestrnvielccPPDPAKK---LLGEPFVLQQAVPVDLFPHTPHCE 378
Cdd:TIGR00479 375 CAAGVLRTIIKLKPER-IVYVSCN--------------PATLARDleaLCKAGYTIARVQPVDMFPHTGHVE 431
|
|
| rumB |
PRK03522 |
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC; |
179-382 |
1.28e-18 |
|
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC;
Pssm-ID: 235128 [Multi-domain] Cd Length: 315 Bit Score: 85.69 E-value: 1.28e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 179 LLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRT----VGELtGVNSdtiLLDICCGTGVIGLSLAQHTSRVLGIE 254
Cdd:PRK03522 127 FLTEQQALPERFNGVPLFIRPQSFFQTNPAVAAQLYATardwVREL-PPRS---MWDLFCGVGGFGLHCATPGMQLTGIE 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 255 LLEQAVEDARWTAAFNGITNSEFH--------TGQAEKilPGLlkskedgqsivAVVNPARAGLHyKVIQAIRNFRAIHT 326
Cdd:PRK03522 203 ISAEAIACAKQSAAELGLTNVQFQaldstqfaTAQGEV--PDL-----------VLVNPPRRGIG-KELCDYLSQMAPRF 268
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1034675346 327 LVFVSCklhgestrNVIELccppdpAKKLLGEP-FVLQQAVPVDLFPHTPHCE-LVLL 382
Cdd:PRK03522 269 ILYSSC--------NAQTM------AKDLAHLPgYRIERVQLFDMFPHTAHYEvLTLL 312
|
|
| tRNA_U5-meth_tr |
pfam05958 |
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC: ... |
178-385 |
3.22e-10 |
|
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalyzed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity.
Pssm-ID: 428692 Cd Length: 357 Bit Score: 60.92 E-value: 3.22e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 178 QLLFGEPYIFEEL----LSLKIRISPDAFFQINTAGAEMLYRTVGELTGvNSDTILLDICCGTGVIGLSLAQHTSRVLGI 253
Cdd:pfam05958 151 KIVLDQDYVDETLpvagREFIYRQVENSFTQPNAAVNIKMLEWACDVTQ-GSKGDLLELYCGNGNFSLALARNFRKVLAT 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 254 ELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKE----------DGQSIVAVVNPARAGLHYKVIQAIRNFRA 323
Cdd:pfam05958 230 EIAKPSVAAAQYNIAANNIDNVQIIRMSAEEFTQAMNGVREfnrlkgidlkSYNCSTIFVDPPRAGLDPETLKLVQAYPR 309
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034675346 324 IhtlVFVSCklhgestrNVIELCcppdpaKKL--LGEPFVLQQAVPVDLFPHTPHCELVLLFTR 385
Cdd:pfam05958 310 I---LYISC--------NPETLC------ANLeqLSKTHRVERFALFDQFPYTHHMECGVLLEK 356
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
229-322 |
1.02e-04 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 41.26 E-value: 1.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 229 LLDICCGTGVIGLSLAQHTS-RVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPgllksKEDGQSIVAVVNPAR 307
Cdd:cd02440 2 VLDLGCGTGALALALASGPGaRVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPP-----EADESFDVIISDPPL 76
|
90
....*....|....*
gi 1034675346 308 AGLHYKVIQAIRNFR 322
Cdd:cd02440 77 HHLVEDLARFLEEAR 91
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
21-384 |
1.61e-59 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 197.32 E-value: 1.61e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 21 LHPIIPSPVINGYRNKSTFSVnrGPDGNPKTVGFYlgtwrdgnvvcvqsnhlknipEKHSqvaqyYEVFlrqsPLEPCLV 100
Cdd:COG2265 109 VEPIIGSPEPWGYRNRARLSV--RRTDGRLRLGFY---------------------ARGS-----HELV----DIDECPL 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 101 FHEggywreltvrtnsqgHTMAIItfhpqklsqeelhvqkEIVKEFFIRGPGAACGLTSLyfqestMTRCshqqspyqll 180
Cdd:COG2265 157 LDP---------------ALNALL----------------PALRELLAELGARRGELRHL------VVRA---------- 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 181 fGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQAV 260
Cdd:COG2265 190 -GRDYLTERLGGLTFRISPGSFFQVNPEQAEALYAAALEWLDLTGGERVLDLYCGVGTFALPLARRAKKVIGVEIVPEAV 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 261 EDARWTAAFNGITNSEFHTGQAEKILPGLLKSKE-DgqsiVAVVNPARAGLHYKVIQAIRNFRAiHTLVFVSCklhgest 339
Cdd:COG2265 269 EDARENARLNGLKNVEFVAGDLEEVLPELLWGGRpD----VVVLDPPRAGAGPEVLEALAALGP-RRIVYVSC------- 336
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 1034675346 340 rnvielccppDPA------KKLLGEPFVLQQAVPVDLFPHTPHCELVLLFT 384
Cdd:COG2265 337 ----------NPAtlardlALLVEGGYRLEKVQPVDMFPHTHHVESVALLE 377
|
|
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
15-378 |
8.33e-31 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 121.85 E-value: 8.33e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 15 ERLSCL-LHPIIPSPVIN----GYRNKSTFSVNRGPDGNPKtVGFY-LGTWR--DGNVVCVQSNHL-------KNIPEKH 79
Cdd:TIGR00479 90 ERIGKFvSEPIEDVPTIGddpwGYRNKARLSLGRSPSGQLQ-AGFYqKGSHDivDVKQCPVQAPALnallpkvRAILENF 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 80 SQVAQYYEVflrqsplepclvfhEGGYWRELTVRTNSQGHTMAI--ITFHpqklsqEELHVQKEIVKEFFIRGP--GAAC 155
Cdd:TIGR00479 169 GASRYLEHK--------------ELGQARHGVLRIGRHTGELSSvdRTAL------ERFPHKEELDLYLQPDSPdvKSIC 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 156 -----GLTSLYFQESTMTrcshqqspyqlLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILL 230
Cdd:TIGR00479 229 qninpEKTNVIFGEETEV-----------IAGEMPIYDKSGDLSFTFSARDFIQVNSGQNEKLVDRALEWLELQGEERVL 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 231 DICCGTGVIGLSLAQHTSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPgllKSKEDGQSI-VAVVNPARAG 309
Cdd:TIGR00479 298 DAYCGMGTFTLPLAKQAKSVVGVEGVPESVEKAQQNAELNGIANVTFYHGTLETVLP---KQPWAGNGFdKVLLDPPRKG 374
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034675346 310 LHYKVIQAIRNFRAIHtLVFVSCKlhgestrnvielccPPDPAKK---LLGEPFVLQQAVPVDLFPHTPHCE 378
Cdd:TIGR00479 375 CAAGVLRTIIKLKPER-IVYVSCN--------------PATLARDleaLCKAGYTIARVQPVDMFPHTGHVE 431
|
|
| rumB |
PRK03522 |
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC; |
179-382 |
1.28e-18 |
|
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC;
Pssm-ID: 235128 [Multi-domain] Cd Length: 315 Bit Score: 85.69 E-value: 1.28e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 179 LLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRT----VGELtGVNSdtiLLDICCGTGVIGLSLAQHTSRVLGIE 254
Cdd:PRK03522 127 FLTEQQALPERFNGVPLFIRPQSFFQTNPAVAAQLYATardwVREL-PPRS---MWDLFCGVGGFGLHCATPGMQLTGIE 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 255 LLEQAVEDARWTAAFNGITNSEFH--------TGQAEKilPGLlkskedgqsivAVVNPARAGLHyKVIQAIRNFRAIHT 326
Cdd:PRK03522 203 ISAEAIACAKQSAAELGLTNVQFQaldstqfaTAQGEV--PDL-----------VLVNPPRRGIG-KELCDYLSQMAPRF 268
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1034675346 327 LVFVSCklhgestrNVIELccppdpAKKLLGEP-FVLQQAVPVDLFPHTPHCE-LVLL 382
Cdd:PRK03522 269 ILYSSC--------NAQTM------AKDLAHLPgYRIERVQLFDMFPHTAHYEvLTLL 312
|
|
| rumA |
PRK13168 |
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; |
173-385 |
7.13e-12 |
|
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD;
Pssm-ID: 237291 [Multi-domain] Cd Length: 443 Bit Score: 66.33 E-value: 7.13e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 173 QQSPYQLLFGepyifeellsLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLG 252
Cdd:PRK13168 255 QLSYYLPEFG----------LRLAFSPRDFIQVNAQVNQKMVARALEWLDPQPGDRVLDLFCGLGNFTLPLARQAAEVVG 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 253 IELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKedgQSIVAV-VNPARAGLhYKVIQAIRNFRAIhTLVFVS 331
Cdd:PRK13168 325 VEGVEAMVERARENARRNGLDNVTFYHANLEEDFTDQPWAL---GGFDKVlLDPPRAGA-AEVMQALAKLGPK-RIVYVS 399
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 332 CklhgestrnvielccppDPA------KKLLGEPFVLQQAVPVDLFPHTPHCELVLLFTR 385
Cdd:PRK13168 400 C-----------------NPAtlardaGVLVEAGYRLKRAGMLDMFPHTGHVESMALFER 442
|
|
| tRNA_U5-meth_tr |
pfam05958 |
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC: ... |
178-385 |
3.22e-10 |
|
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalyzed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity.
Pssm-ID: 428692 Cd Length: 357 Bit Score: 60.92 E-value: 3.22e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 178 QLLFGEPYIFEEL----LSLKIRISPDAFFQINTAGAEMLYRTVGELTGvNSDTILLDICCGTGVIGLSLAQHTSRVLGI 253
Cdd:pfam05958 151 KIVLDQDYVDETLpvagREFIYRQVENSFTQPNAAVNIKMLEWACDVTQ-GSKGDLLELYCGNGNFSLALARNFRKVLAT 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 254 ELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKE----------DGQSIVAVVNPARAGLHYKVIQAIRNFRA 323
Cdd:pfam05958 230 EIAKPSVAAAQYNIAANNIDNVQIIRMSAEEFTQAMNGVREfnrlkgidlkSYNCSTIFVDPPRAGLDPETLKLVQAYPR 309
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034675346 324 IhtlVFVSCklhgestrNVIELCcppdpaKKL--LGEPFVLQQAVPVDLFPHTPHCELVLLFTR 385
Cdd:pfam05958 310 I---LYISC--------NPETLC------ANLeqLSKTHRVERFALFDQFPYTHHMECGVLLEK 356
|
|
| TrmN6 |
COG4123 |
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ... |
223-274 |
4.17e-08 |
|
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 443299 [Multi-domain] Cd Length: 238 Bit Score: 53.61 E-value: 4.17e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034675346 223 VNSDTILL-------------DICCGTGVIGLSLAQHTS--RVLGIELLEQAVEDARWTAAFNGITN 274
Cdd:COG4123 22 FGTDAVLLaafapvkkggrvlDLGTGTGVIALMLAQRSPgaRITGVEIQPEAAELARRNVALNGLED 88
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
229-280 |
5.83e-08 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 52.50 E-value: 5.83e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1034675346 229 LLDICCGTGVIGLSLAQHT--SRVLGIELLEQAVEDARWTAAFNGITNSEFHTG 280
Cdd:COG2813 53 VLDLGCGYGVIGLALAKRNpeARVTLVDVNARAVELARANAAANGLENVEVLWS 106
|
|
| PRK05031 |
PRK05031 |
tRNA (uracil-5-)-methyltransferase; Validated |
179-382 |
3.31e-07 |
|
tRNA (uracil-5-)-methyltransferase; Validated
Pssm-ID: 235332 Cd Length: 362 Bit Score: 51.75 E-value: 3.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 179 LLFGEPYIFEEL----LSLKIRISPDAFFQINTAGAE-MLYRTVGELTGVNSDtiLLDICCGTGVIGLSLAQHTSRVLGI 253
Cdd:PRK05031 157 IVLDQDYVDERLpvagREFIYRQVENSFTQPNAAVNEkMLEWALDATKGSKGD--LLELYCGNGNFTLALARNFRRVLAT 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 254 ELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKE------------DGQSIvaVVNPARAGLHYKVIQAIRNF 321
Cdd:PRK05031 235 EISKPSVAAAQYNIAANGIDNVQIIRMSAEEFTQAMNGVREfnrlkgidlksyNFSTI--FVDPPRAGLDDETLKLVQAY 312
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034675346 322 RAIhtlVFVSCK---LHgestRNVIELCCPPDPAKkllgepFVLqqavpVDLFPHTPHCEL-VLL 382
Cdd:PRK05031 313 ERI---LYISCNpetLC----ENLETLSQTHKVER------FAL-----FDQFPYTHHMECgVLL 359
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
230-285 |
1.18e-06 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 46.40 E-value: 1.18e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1034675346 230 LDICCGTGVIGLSLAQHT-SRVLGIELLEQAVEDARWTAAFNGItNSEFHTGQAEKI 285
Cdd:pfam13649 2 LDLGCGTGRLTLALARRGgARVTGVDLSPEMLERARERAAEAGL-NVEFVQGDAEDL 57
|
|
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
213-285 |
2.17e-06 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 46.91 E-value: 2.17e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034675346 213 LYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQAVEDARWTAAFNGItNSEFHTGQAEKI 285
Cdd:COG2226 10 GREALLAALGLRPGARVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGL-NVEFVVGDAEDL 81
|
|
| HemK |
COG2890 |
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ... |
182-280 |
4.37e-06 |
|
Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442135 [Multi-domain] Cd Length: 282 Bit Score: 47.84 E-value: 4.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 182 GEP--YI--FEELLSLKIRISPDAFfqI---NTagaEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQH--TSRVLG 252
Cdd:COG2890 67 GEPlaYIlgEAEFYGLEFKVDPGVL--IprpET---EELVELALALLPAGAPPRVLDLGTGSGAIALALAKErpDARVTA 141
|
90 100
....*....|....*....|....*....
gi 1034675346 253 IELLEQAVEDARWTAAFNGITNS-EFHTG 280
Cdd:COG2890 142 VDISPDALAVARRNAERLGLEDRvRFLQG 170
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
224-285 |
7.92e-06 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 45.49 E-value: 7.92e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034675346 224 NSDTILLDICCGTGVIGLSLAQHT---SRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKI 285
Cdd:pfam13847 2 DKGMRVLDLGCGTGHLSFELAEELgpnAEVVGIDISEEAIEKARENAQKLGFDNVEFEQGDIEEL 66
|
|
| PRK09328 |
PRK09328 |
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional |
230-280 |
1.39e-05 |
|
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
Pssm-ID: 236467 [Multi-domain] Cd Length: 275 Bit Score: 46.31 E-value: 1.39e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1034675346 230 LDICCGTGVIGLSLAQH--TSRVLGIELLEQAVEDARWTAAFNGITNSEFHTG 280
Cdd:PRK09328 113 LDLGTGSGAIALALAKErpDAEVTAVDISPEALAVARRNAKHGLGARVEFLQG 165
|
|
| UbiG |
COG2227 |
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ... |
229-285 |
2.67e-05 |
|
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 441829 [Multi-domain] Cd Length: 126 Bit Score: 43.47 E-value: 2.67e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1034675346 229 LLDICCGTGVIGLSLAQHTSRVLGIELLEQAVEDARWTAAFNGItnsEFHTGQAEKI 285
Cdd:COG2227 28 VLDVGCGTGRLALALARRGADVTGVDISPEALEIARERAAELNV---DFVQGDLEDL 81
|
|
| SmtA |
COG0500 |
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ... |
230-287 |
3.98e-05 |
|
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];
Pssm-ID: 440266 [Multi-domain] Cd Length: 199 Bit Score: 44.14 E-value: 3.98e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1034675346 230 LDICCGTGVIGLSLAQHT-SRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILP 287
Cdd:COG0500 31 LDLGCGTGRNLLALAARFgGRVIGIDLSPEAIALARARAAKAGLGNVEFLVADLAELDP 89
|
|
| MTS |
pfam05175 |
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ... |
230-318 |
9.03e-05 |
|
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.
Pssm-ID: 428349 [Multi-domain] Cd Length: 170 Bit Score: 42.58 E-value: 9.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 230 LDICCGTGVIGLSLAQHTSRVlGIELLE---QAVEDARWTAAFNGITNSEFHTGQaekilpgLLKSKEDGQSIVAVVNPA 306
Cdd:pfam05175 36 LDLGCGAGVLGAALAKESPDA-ELTMVDinaRALESARENLAANGLENGEVVASD-------VYSGVEDGKFDLIISNPP 107
|
90
....*....|....*
gi 1034675346 307 -RAGLH--YKVIQAI 318
Cdd:pfam05175 108 fHAGLAttYNVAQRF 122
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
229-322 |
1.02e-04 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 41.26 E-value: 1.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 229 LLDICCGTGVIGLSLAQHTS-RVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPgllksKEDGQSIVAVVNPAR 307
Cdd:cd02440 2 VLDLGCGTGALALALASGPGaRVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPP-----EADESFDVIISDPPL 76
|
90
....*....|....*
gi 1034675346 308 AGLHYKVIQAIRNFR 322
Cdd:cd02440 77 HHLVEDLARFLEEAR 91
|
|
| PrmA |
pfam06325 |
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal ... |
223-301 |
1.14e-04 |
|
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.
Pssm-ID: 428888 [Multi-domain] Cd Length: 294 Bit Score: 43.41 E-value: 1.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675346 223 VNSDTILLDICCGTGVigLSLAQH---TSRVLGIELLEQAVEDARWTAAFNGITNsefhtgQAEKILPG-LLKSKEDGqs 298
Cdd:pfam06325 159 VKPGESVLDVGCGSGI--LAIAALklgAKKVVGVDIDPVAVRAAKENAELNGVEA------RLEVYLPGdLPKEKADV-- 228
|
...
gi 1034675346 299 IVA 301
Cdd:pfam06325 229 VVA 231
|
|
| COG4976 |
COG4976 |
Predicted methyltransferase, contains TPR repeat [General function prediction only]; |
230-264 |
1.42e-04 |
|
Predicted methyltransferase, contains TPR repeat [General function prediction only];
Pssm-ID: 444001 [Multi-domain] Cd Length: 181 Bit Score: 42.29 E-value: 1.42e-04
10 20 30
....*....|....*....|....*....|....*
gi 1034675346 230 LDICCGTGVIGLSLAQHTSRVLGIELLEQAVEDAR 264
Cdd:COG4976 51 LDLGCGTGLLGEALRPRGYRLTGVDLSEEMLAKAR 85
|
|
| Trm11 |
COG1041 |
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ... |
215-285 |
1.02e-03 |
|
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440663 [Multi-domain] Cd Length: 172 Bit Score: 39.55 E-value: 1.02e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034675346 215 RTVGELTGVNSDTILLDICCGTGVI---GLSLAqhtSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKI 285
Cdd:COG1041 16 RALVNLAGAKEGDTVLDPFCGTGTIlieAGLLG---RRVIGSDIDPKMVEGARENLEHYGYEDADVIRGDARDL 86
|
|
| PRK14968 |
PRK14968 |
putative methyltransferase; Provisional |
230-274 |
1.83e-03 |
|
putative methyltransferase; Provisional
Pssm-ID: 237872 [Multi-domain] Cd Length: 188 Bit Score: 39.11 E-value: 1.83e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 1034675346 230 LDICCGTGVIGLSLAQHTSRVLGIELLEQAVEDARWTAAFNGITN 274
Cdd:PRK14968 28 LEVGTGSGIVAIVAAKNGKKVVGVDINPYAVECAKCNAKLNNIRN 72
|
|
| Tam |
COG4106 |
Trans-aconitate methyltransferase [Energy production and conversion]; |
230-288 |
2.63e-03 |
|
Trans-aconitate methyltransferase [Energy production and conversion];
Pssm-ID: 443282 [Multi-domain] Cd Length: 100 Bit Score: 37.11 E-value: 2.63e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034675346 230 LDICCGTGVIGLSLAQHT--SRVLGIELLEQAVEDARwtAAFNGITnseFHTGQAEKILPG 288
Cdd:COG4106 6 LDLGCGTGRLTALLAERFpgARVTGVDLSPEMLARAR--ARLPNVR---FVVADLRDLDPP 61
|
|
| |
