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Conserved domains on  [gi|1034648358|ref|XP_016865719|]
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transmembrane protein 200A isoform X1 [Homo sapiens]

Protein Classification

TMEM200 family protein( domain architecture ID 10562785)

TMEM200 family protein is a DUF2371 domain-containing protein; similar to Homo sapiens transmembrane proteins 200A and 200C

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF2371 pfam10177
Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from ...
16-161 3.35e-86

Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from nematodes to humans. The function is not known.


:

Pssm-ID: 462979  Cd Length: 141  Bit Score: 261.10  E-value: 3.35e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034648358  16 RQDSARSQQHVNlspspaTQEKKPIRRRPRADVVVVRGKIRLYSPSGFFLILGVLISIIGIAMAVLGYWPQKEHFIDAET 95
Cdd:pfam10177   1 RQDSLRSQHRVE------NKRKRKRKKKRRADVVVVKGKLRLCSPSGFFALLGILVLLVGIAMAVLGYWPHEVAQLGSRN 74
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034648358  96 TLSTNETQVI-RNEGGVVVRFFEQHLHSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMR 161
Cdd:pfam10177  75 NNSSNSTAEMsRDHSGFLARFLEQYLHSDKMKVFGPLIMGIGIFLFICANAVLHENRDKETKIINLR 141
 
Name Accession Description Interval E-value
DUF2371 pfam10177
Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from ...
16-161 3.35e-86

Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from nematodes to humans. The function is not known.


Pssm-ID: 462979  Cd Length: 141  Bit Score: 261.10  E-value: 3.35e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034648358  16 RQDSARSQQHVNlspspaTQEKKPIRRRPRADVVVVRGKIRLYSPSGFFLILGVLISIIGIAMAVLGYWPQKEHFIDAET 95
Cdd:pfam10177   1 RQDSLRSQHRVE------NKRKRKRKKKRRADVVVVKGKLRLCSPSGFFALLGILVLLVGIAMAVLGYWPHEVAQLGSRN 74
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034648358  96 TLSTNETQVI-RNEGGVVVRFFEQHLHSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMR 161
Cdd:pfam10177  75 NNSSNSTAEMsRDHSGFLARFLEQYLHSDKMKVFGPLIMGIGIFLFICANAVLHENRDKETKIINLR 141
 
Name Accession Description Interval E-value
DUF2371 pfam10177
Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from ...
16-161 3.35e-86

Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from nematodes to humans. The function is not known.


Pssm-ID: 462979  Cd Length: 141  Bit Score: 261.10  E-value: 3.35e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034648358  16 RQDSARSQQHVNlspspaTQEKKPIRRRPRADVVVVRGKIRLYSPSGFFLILGVLISIIGIAMAVLGYWPQKEHFIDAET 95
Cdd:pfam10177   1 RQDSLRSQHRVE------NKRKRKRKKKRRADVVVVKGKLRLCSPSGFFALLGILVLLVGIAMAVLGYWPHEVAQLGSRN 74
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034648358  96 TLSTNETQVI-RNEGGVVVRFFEQHLHSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMR 161
Cdd:pfam10177  75 NNSSNSTAEMsRDHSGFLARFLEQYLHSDKMKVFGPLIMGIGIFLFICANAVLHENRDKETKIINLR 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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