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Conserved domains on  [gi|767944871|ref|XP_011513433|]
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ATP-binding cassette sub-family A member 13 isoform X2 [Homo sapiens]

Protein Classification

ABC transporter A family member( domain architecture ID 1000606)

ABC transporter A family member (ABCA) may mediate the transport of a variety of lipid compounds

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
rim_protein super family cl31083
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
3068-5018 0e+00

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


The actual alignment was detected with superfamily member TIGR01257:

Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 1064.24  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3068 VKIKDLMKNITKLTEELRSSIQISNETIHSILEANISHSKVLFSALTVALSG-KCDQEILHLLLTFPKGEKSWIAAEELC 3146
Cdd:TIGR01257  151 IRIRDILKDEEALTLFLMKNIGLSDSVVYLLVNSQVRPEQFAYGVPDLELKDiACSEALLERFIIFSQRRGAQTVRDALC 230
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3147 SLPGSKVYSLIVLLSRNLDV-RAF-IYKTLMPSEANGL-LNSLLDIVSSLSALLAKaqhvFEYLPEFLHTFKIT-ALLET 3222
Cdd:TIGR01257  231 SLSQGTLQWIEDTLYANVDFfKLFhVLPTLLDSRSQGInLRSWGGILSDMSPRIQE----FIHRPSVQDLLWVTrPLLQN 306
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3223 LDFQQVSQNVQARSSAF-------GSFQFVMkmvckdqaSFLSDSNMfinlprvKELLEDDKEK----FNIPEDSTPFCL 3291
Cdd:TIGR01257  307 GGPETFTQLMGILSDLLcgypeggGSRVFSF--------NWYEDNNY-------KAFLGIDSTRkdpiYSYDKRTTSFCN 371
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3292 KLYQEILQLPNGALVWTFLKPILHGKILYTPNTPEINKVIQKANYTFYIVDKLKTLSETLLEMSS----LFQRSGsgQMf 3367
Cdd:TIGR01257  372 ALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARRILKNANSTFEELERVRKLVKAWEEVGPqiwyFFDKST--QM- 448
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3368 NQLQEALRNKFVRNFVENQLH---IDVDKLTEKLQT--YGGLLDEMFNHAGAGRF----RFLGsiLVN-LSSCVALNRFQ 3437
Cdd:TIGR01257  449 TMIRDTLQNPTVKDFINRQLGeegITAEAVLNFLYNgpREKQADDMTNFDWRDIFnitdRFLR--LANqYLECLVLDKFE 526
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3438 ALQSVDILETKAHELLQQNSFLASIIFSNslfdknFRSESVKLPPHVSYTIRTNVLYSVRTDVVKNPSWKFHPQNLPADG 3517
Cdd:TIGR01257  527 SYDDEVQLTQRALSLLEENRFWAGVVFPD------MYPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVED 600
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3518 FKYNYV-FAPLQDMIERAIILVQTgQEALEPAAQTQAAPYPCHTSDLFLNNVGFFFPLIMMLTWMVSVASMVRKLVYEQE 3596
Cdd:TIGR01257  601 FRYIWGgFAYLQDMVEQGITRSQM-QAEPPVGIYLQQMPYPCFVDDSFMIILNRCFPIFMVLAWIYSVSMTVKSIVLEKE 679
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3597 IQIEEYMRMMGVHPVIHFLAWFLENMAVLTISSATLAIVLKTSGIFAHSNTFIVFLFLLDFGMSVVMLSYLLSAFFSQAN 3676
Cdd:TIGR01257  680 LRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGRILHYSDPFILFLFLLAFSTATIMQCFLLSTFFSKAS 759
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3677 TAALCTSLVYMISFLPYIVLLVLHNQLSFVNQTFLCLLSTTAFGQGVFFITFLEGQETGIQWNNMYQA-LEQGGMTFGWV 3755
Cdd:TIGR01257  760 LAAACSGVIYFTLYLPHILCFAWQDRMTADLKTAVSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSpLEGDEFSFLLS 839
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3756 CWMILFDSSLYFLCGWYLSNLIPGTFGLRKPWYFPFTASYWKSVGFLVEKRQYFLSSSLFFFNENFDNKGSSLQNR---E 3832
Cdd:TIGR01257  840 MKMMLLDAALYGLLAWYLDQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTEPLTEEMEDPEHPEGINDsffE 919
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3833 GELEGSAPGVTLVSVTKEYEGH-KAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLS 3911
Cdd:TIGR01257  920 RELPGLVPGVCVKNLVKIFEPSgRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETNLD 999
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3912 RVRMELGVCPQQDILLDNLTVREHLLLFASIKAPQWTKKELhqQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFM 3991
Cdd:TIGR01257 1000 AVRQSLGMCPQHNILFHHLTVAEHILFYAQLKGRSWEEAQL--EMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFV 1077
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3992 GMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPFCLKEAYGQGLRL 4071
Cdd:TIGR01257 1078 GDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTPLFLKNCFGTGFYL 1157
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4072 TLTRQPSVLEAH------------------------DLK-------DMACVTSLIKIYIPQAFLKDSSGSELTYTIP-KD 4119
Cdd:TIGR01257 1158 TLVRKMKNIQSQrggcegtcsctskgfstrcparvdEITpeqvldgDVNELMDLVYHHVPEAKLVECIGQELIFLLPnKN 1237
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4120 TDKACLKGLFQALDENLHQLHLTGYGISDTTLEEVFLMLLQDSNKKSHIALGTESELQN---------------HRPTGH 4184
Cdd:TIGR01257 1238 FKQRAYASLFRELEETLADLGLSSFGISDTPLEEIFLKVTEDADSGSLFAGGAQQKRENanlrhpcsgptekagQTPQAS 1317
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4185 LSGYCGSLARPATVQ--------------GVQLLRAQVAAILARRLRRTLRAGKSTLADLLLPVLFVALAMGLFMVRPLA 4250
Cdd:TIGR01257 1318 HTCSPGQPAAHPEGQpppepedpgvplntGARLILQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIIIPPF 1397
                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4251 TEYPPLRLTPGHYQRAETYF-FSSSGGDNLD-LTRVLLRK--FRDQ--------DLPCAdlnprqkNSSCWRTdPFSHPE 4318
Cdd:TIGR01257 1398 GEYPALTLHPWMYGQQYTFFsMDEPNSEHLEvLADVLLNKpgFGNRclkeewlpEYPCG-------NSTPWKT-PSVSPN 1469
                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4319 ----FQD----------SCGCL---------KCPNRSAS--APYLTNHLGHTLLNLSGFNMEEYLLA--PS--------- 4362
Cdd:TIGR01257 1470 ithlFQKqkwtaahpspSCRCStrekltmlpECPEGAGGlpPPQRTQRSTEILQDLTDRNISDFLVKtyPAlirsslksk 1549
                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4363 ---EKPRLGGWSFGLKIPS-----EA-------GGANGNISKPPTL-------------------AKVWYNQKGFHSLPS 4408
Cdd:TIGR01257 1550 fwvNEQRYGGISIGGKLPAipitgEAlvgflsdLGQMMNVSGGPVTreaskempdflkhletednIKVWFNNKGWHALVS 1629
                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4409 YLNHLNNLILWQHLPPTVDWRQYGITLYSHPYG--GALLNEDKILESIRQCGVALCIVLGFSILSASI------------ 4474
Cdd:TIGR01257 1630 FLNVAHNAILRASLPKDRDPEEYGITVISQPLNltKEQLSEITVLTTSVDAVVAICVIFAMSFVPASFvlyliqervnka 1709
                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4475 -------GSS------------VLFYLVSVCLCVAVIVAFQLTAFTFRKNLAATALLLSLFGYATLPWMYLMSRIFSSSD 4535
Cdd:TIGR01257 1710 khlqfisGVSpttywltnflwdIMNYAVSAGLVVGIFIGFQKKAYTSPENLPALVALLMLYGWAVIPMMYPASFLFDVPS 1789
                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4536 VAFISYVSLNFIFGLCTMLITImprLLAIISKAKNLQNIYDVLKWVFTIFPQFCLGQGLVELCYNQIKYDLTHNFGIDSY 4615
Cdd:TIGR01257 1790 TAYVALSCANLFIGINSSAITF---VLELFENNRTLLRFNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDVYAQFGEEHS 1866
                         1770      1780      1790      1800      1810      1820      1830      1840
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4616 VSPFEMNFLGWIFVQLASQGTV--LLLLRVLLHWDLLRWPrGHSTLQGTVksSKDTDVEKEEKRVFEGRTNGDILVLYNL 4693
Cdd:TIGR01257 1867 ANPFQWDLIGKNLVAMAVEGVVyfLLTLLIQHHFFLSRWI-AEPAKEPIF--DEDDDVAEERQRIISGGNKTDILRLNEL 1943
                         1850      1860      1870      1880      1890      1900      1910      1920
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4694 SKHYRRffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAiirTPMGDAVdLSSAGTAGVLIGYC 4773
Cdd:TIGR01257 1944 TKVYSG--TSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDA---TVAGKSI-LTNISDVHQNMGYC 2017
                         1930      1940      1950      1960      1970      1980      1990      2000
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4774 PQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEP 4853
Cdd:TIGR01257 2018 PQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEP 2097
                         2010      2020      2030      2040      2050      2060      2070      2080
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4854 SSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKNRFGDGYTVKVWLCKEANQ 4933
Cdd:TIGR01257 2098 TTGMDPQARRMLWNTIVSIIREGRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGTIQHLKSKFGDGYIVTMKIKSPKDD 2177
                         2090      2100      2110      2120      2130      2140      2150      2160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4934 HC----TVSDHLKLYFPGIQFKGQHLNLLEYHVPKrwGCLADLFKVIENNKTFLNIKHYSINQTTLEQVFINFASEQQQT 5009
Cdd:TIGR01257 2178 LLpdlnPVEQFFQGNFPGSVQRERHYNMLQFQVSS--SSLARIFQLLISHKDSLLIEEYSVTQTTLDQVFVNFAKQQTET 2255

                   ....*....
gi 767944871  5010 LQSTLDPST 5018
Cdd:TIGR01257 2256 YDLPLHPRA 2264
rim_protein super family cl31083
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
7-82 1.66e-11

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


The actual alignment was detected with superfamily member TIGR01257:

Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 71.58  E-value: 1.66e-11
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871     7 QFKALLWKNWLCRLRNPVLFLAEFFWPCILFVILTVLRFQEPPRYRDICYLQPRDLPSCGVIPFVQSLLCNTGSRC 82
Cdd:TIGR01257    6 QIQLLLWKNWTLRKRQKIRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPC 81
 
Name Accession Description Interval E-value
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
3068-5018 0e+00

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 1064.24  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3068 VKIKDLMKNITKLTEELRSSIQISNETIHSILEANISHSKVLFSALTVALSG-KCDQEILHLLLTFPKGEKSWIAAEELC 3146
Cdd:TIGR01257  151 IRIRDILKDEEALTLFLMKNIGLSDSVVYLLVNSQVRPEQFAYGVPDLELKDiACSEALLERFIIFSQRRGAQTVRDALC 230
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3147 SLPGSKVYSLIVLLSRNLDV-RAF-IYKTLMPSEANGL-LNSLLDIVSSLSALLAKaqhvFEYLPEFLHTFKIT-ALLET 3222
Cdd:TIGR01257  231 SLSQGTLQWIEDTLYANVDFfKLFhVLPTLLDSRSQGInLRSWGGILSDMSPRIQE----FIHRPSVQDLLWVTrPLLQN 306
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3223 LDFQQVSQNVQARSSAF-------GSFQFVMkmvckdqaSFLSDSNMfinlprvKELLEDDKEK----FNIPEDSTPFCL 3291
Cdd:TIGR01257  307 GGPETFTQLMGILSDLLcgypeggGSRVFSF--------NWYEDNNY-------KAFLGIDSTRkdpiYSYDKRTTSFCN 371
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3292 KLYQEILQLPNGALVWTFLKPILHGKILYTPNTPEINKVIQKANYTFYIVDKLKTLSETLLEMSS----LFQRSGsgQMf 3367
Cdd:TIGR01257  372 ALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARRILKNANSTFEELERVRKLVKAWEEVGPqiwyFFDKST--QM- 448
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3368 NQLQEALRNKFVRNFVENQLH---IDVDKLTEKLQT--YGGLLDEMFNHAGAGRF----RFLGsiLVN-LSSCVALNRFQ 3437
Cdd:TIGR01257  449 TMIRDTLQNPTVKDFINRQLGeegITAEAVLNFLYNgpREKQADDMTNFDWRDIFnitdRFLR--LANqYLECLVLDKFE 526
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3438 ALQSVDILETKAHELLQQNSFLASIIFSNslfdknFRSESVKLPPHVSYTIRTNVLYSVRTDVVKNPSWKFHPQNLPADG 3517
Cdd:TIGR01257  527 SYDDEVQLTQRALSLLEENRFWAGVVFPD------MYPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVED 600
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3518 FKYNYV-FAPLQDMIERAIILVQTgQEALEPAAQTQAAPYPCHTSDLFLNNVGFFFPLIMMLTWMVSVASMVRKLVYEQE 3596
Cdd:TIGR01257  601 FRYIWGgFAYLQDMVEQGITRSQM-QAEPPVGIYLQQMPYPCFVDDSFMIILNRCFPIFMVLAWIYSVSMTVKSIVLEKE 679
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3597 IQIEEYMRMMGVHPVIHFLAWFLENMAVLTISSATLAIVLKTSGIFAHSNTFIVFLFLLDFGMSVVMLSYLLSAFFSQAN 3676
Cdd:TIGR01257  680 LRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGRILHYSDPFILFLFLLAFSTATIMQCFLLSTFFSKAS 759
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3677 TAALCTSLVYMISFLPYIVLLVLHNQLSFVNQTFLCLLSTTAFGQGVFFITFLEGQETGIQWNNMYQA-LEQGGMTFGWV 3755
Cdd:TIGR01257  760 LAAACSGVIYFTLYLPHILCFAWQDRMTADLKTAVSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSpLEGDEFSFLLS 839
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3756 CWMILFDSSLYFLCGWYLSNLIPGTFGLRKPWYFPFTASYWKSVGFLVEKRQYFLSSSLFFFNENFDNKGSSLQNR---E 3832
Cdd:TIGR01257  840 MKMMLLDAALYGLLAWYLDQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTEPLTEEMEDPEHPEGINDsffE 919
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3833 GELEGSAPGVTLVSVTKEYEGH-KAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLS 3911
Cdd:TIGR01257  920 RELPGLVPGVCVKNLVKIFEPSgRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETNLD 999
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3912 RVRMELGVCPQQDILLDNLTVREHLLLFASIKAPQWTKKELhqQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFM 3991
Cdd:TIGR01257 1000 AVRQSLGMCPQHNILFHHLTVAEHILFYAQLKGRSWEEAQL--EMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFV 1077
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3992 GMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPFCLKEAYGQGLRL 4071
Cdd:TIGR01257 1078 GDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTPLFLKNCFGTGFYL 1157
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4072 TLTRQPSVLEAH------------------------DLK-------DMACVTSLIKIYIPQAFLKDSSGSELTYTIP-KD 4119
Cdd:TIGR01257 1158 TLVRKMKNIQSQrggcegtcsctskgfstrcparvdEITpeqvldgDVNELMDLVYHHVPEAKLVECIGQELIFLLPnKN 1237
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4120 TDKACLKGLFQALDENLHQLHLTGYGISDTTLEEVFLMLLQDSNKKSHIALGTESELQN---------------HRPTGH 4184
Cdd:TIGR01257 1238 FKQRAYASLFRELEETLADLGLSSFGISDTPLEEIFLKVTEDADSGSLFAGGAQQKRENanlrhpcsgptekagQTPQAS 1317
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4185 LSGYCGSLARPATVQ--------------GVQLLRAQVAAILARRLRRTLRAGKSTLADLLLPVLFVALAMGLFMVRPLA 4250
Cdd:TIGR01257 1318 HTCSPGQPAAHPEGQpppepedpgvplntGARLILQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIIIPPF 1397
                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4251 TEYPPLRLTPGHYQRAETYF-FSSSGGDNLD-LTRVLLRK--FRDQ--------DLPCAdlnprqkNSSCWRTdPFSHPE 4318
Cdd:TIGR01257 1398 GEYPALTLHPWMYGQQYTFFsMDEPNSEHLEvLADVLLNKpgFGNRclkeewlpEYPCG-------NSTPWKT-PSVSPN 1469
                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4319 ----FQD----------SCGCL---------KCPNRSAS--APYLTNHLGHTLLNLSGFNMEEYLLA--PS--------- 4362
Cdd:TIGR01257 1470 ithlFQKqkwtaahpspSCRCStrekltmlpECPEGAGGlpPPQRTQRSTEILQDLTDRNISDFLVKtyPAlirsslksk 1549
                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4363 ---EKPRLGGWSFGLKIPS-----EA-------GGANGNISKPPTL-------------------AKVWYNQKGFHSLPS 4408
Cdd:TIGR01257 1550 fwvNEQRYGGISIGGKLPAipitgEAlvgflsdLGQMMNVSGGPVTreaskempdflkhletednIKVWFNNKGWHALVS 1629
                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4409 YLNHLNNLILWQHLPPTVDWRQYGITLYSHPYG--GALLNEDKILESIRQCGVALCIVLGFSILSASI------------ 4474
Cdd:TIGR01257 1630 FLNVAHNAILRASLPKDRDPEEYGITVISQPLNltKEQLSEITVLTTSVDAVVAICVIFAMSFVPASFvlyliqervnka 1709
                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4475 -------GSS------------VLFYLVSVCLCVAVIVAFQLTAFTFRKNLAATALLLSLFGYATLPWMYLMSRIFSSSD 4535
Cdd:TIGR01257 1710 khlqfisGVSpttywltnflwdIMNYAVSAGLVVGIFIGFQKKAYTSPENLPALVALLMLYGWAVIPMMYPASFLFDVPS 1789
                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4536 VAFISYVSLNFIFGLCTMLITImprLLAIISKAKNLQNIYDVLKWVFTIFPQFCLGQGLVELCYNQIKYDLTHNFGIDSY 4615
Cdd:TIGR01257 1790 TAYVALSCANLFIGINSSAITF---VLELFENNRTLLRFNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDVYAQFGEEHS 1866
                         1770      1780      1790      1800      1810      1820      1830      1840
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4616 VSPFEMNFLGWIFVQLASQGTV--LLLLRVLLHWDLLRWPrGHSTLQGTVksSKDTDVEKEEKRVFEGRTNGDILVLYNL 4693
Cdd:TIGR01257 1867 ANPFQWDLIGKNLVAMAVEGVVyfLLTLLIQHHFFLSRWI-AEPAKEPIF--DEDDDVAEERQRIISGGNKTDILRLNEL 1943
                         1850      1860      1870      1880      1890      1900      1910      1920
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4694 SKHYRRffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAiirTPMGDAVdLSSAGTAGVLIGYC 4773
Cdd:TIGR01257 1944 TKVYSG--TSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDA---TVAGKSI-LTNISDVHQNMGYC 2017
                         1930      1940      1950      1960      1970      1980      1990      2000
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4774 PQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEP 4853
Cdd:TIGR01257 2018 PQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEP 2097
                         2010      2020      2030      2040      2050      2060      2070      2080
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4854 SSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKNRFGDGYTVKVWLCKEANQ 4933
Cdd:TIGR01257 2098 TTGMDPQARRMLWNTIVSIIREGRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGTIQHLKSKFGDGYIVTMKIKSPKDD 2177
                         2090      2100      2110      2120      2130      2140      2150      2160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4934 HC----TVSDHLKLYFPGIQFKGQHLNLLEYHVPKrwGCLADLFKVIENNKTFLNIKHYSINQTTLEQVFINFASEQQQT 5009
Cdd:TIGR01257 2178 LLpdlnPVEQFFQGNFPGSVQRERHYNMLQFQVSS--SSLARIFQLLISHKDSLLIEEYSVTQTTLDQVFVNFAKQQTET 2255

                   ....*....
gi 767944871  5010 LQSTLDPST 5018
Cdd:TIGR01257 2256 YDLPLHPRA 2264
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
4688-4914 1.38e-94

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 305.97  E-value: 1.38e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYRRFFQniIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmgDAVDLSSAGTAG 4767
Cdd:cd03263     1 LQIRNLTKTYKKGTK--PAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYIN----GYSIRTDRKAAR 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4768 VLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDI 4847
Cdd:cd03263    75 QSLGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSV 154
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4848 LLLDEPSSGMDPCSKRYLWQTImKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIK 4914
Cdd:cd03263   155 LLLDEPTSGLDPASRRAIWDLI-LEVRKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
3842-4058 5.88e-77

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 256.14  E-value: 5.88e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCP 3921
Cdd:COG1131     1 IEVRGLTKRYGDKTAL-DGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEVRRRIGYVP 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QQDILLDNLTVREHLLLFASIKapQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDE 4001
Cdd:COG1131    80 QEPALYPDLTVRENLRFFARLY--GLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDE 157
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4002 PTSGVDPCSRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:COG1131   158 PTSGLDPEARRELWELLRELAaEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTP 215
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
3820-4061 1.77e-41

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 158.07  E-value: 1.77e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3820 NFDNKGSSLQNREGELEGSAPGVT--LVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSG 3897
Cdd:PRK13536   18 PIERKHQGISEAKASIPGSMSTVAidLAGVSKSY-GDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAG 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3898 TIIINGKNLQTDLSRVRMELGVCPQQDILLDNLTVREHLLLFAsiKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALS 3977
Cdd:PRK13536   97 KITVLGVPVPARARLARARIGVVPQFDNLDLEFTVRENLLVFG--RYFGMSTREIEAVIPSLLEFARLESKADARVSDLS 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3978 GGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDIL--LKYReGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCC 4055
Cdd:PRK13536  175 GGMKRRLTLARALINDPQLLILDEPTTGLDPHARHLIWERLrsLLAR-GKTILLTTHFMEEAERLCDRLCVLEAGRKIAE 253

                  ....*.
gi 767944871 4056 GPPFCL 4061
Cdd:PRK13536  254 GRPHAL 259
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
3858-4004 1.06e-33

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 128.92  E-value: 1.06e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3858 VQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQ-TDLSRVRMELGVCPQQDILLDNLTVREHL 3936
Cdd:pfam00005    1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTdDERKSLRKEIGYVFQDPQLFPRLTVRENL 80
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871  3937 LLFASIKApqWTKKELHQQVNQTLQDVDLT----QHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTS 4004
Cdd:pfam00005   81 RLGLLLKG--LSKREKDARAEEALEKLGLGdladRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
3858-4066 1.83e-24

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 113.68  E-value: 1.83e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3858 VQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTI-----IINGKNLQTdlsrvRMELGVCPQQDILLDNLTV 3932
Cdd:NF033858  282 VDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAwlfgqPVDAGDIAT-----RRRVGYMSQAFSLYGELTV 356
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3933 REHLLLFAsiKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRH 4012
Cdd:NF033858  357 RQNLELHA--RLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARD 434
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4013 SLWDIL--LKYREGRTIIFTTHHLDEAEaLSDRVAvLQH-GRLRCCGPPFCLKEAYG 4066
Cdd:NF033858  435 MFWRLLieLSREDGVTIFISTHFMNEAE-RCDRIS-LMHaGRVLASDTPAALVAARG 489
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
4698-4918 1.47e-22

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 107.52  E-value: 1.47e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4698 RRF--FqniIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpMGDAVDlssagtAGVL-----I 4770
Cdd:NF033858  274 MRFgdF---TAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWL---FGQPVD------AGDIatrrrV 341
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4771 GYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLL 4850
Cdd:NF033858  342 GYMSQAFSLYGELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLIL 421
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4851 DEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEaLCTRLAIMVNGsfKCL--GSPQHIKNRFG 4918
Cdd:NF033858  422 DEPTSGVDPVARDMFWRLLIELSREdGVTIFISTHFMNEAE-RCDRISLMHAG--RVLasDTPAALVAARG 489
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
4706-4888 5.91e-22

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 96.53  E-value: 5.91e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGevsltsghaiIRTPMGDAVdlssAGTAGVLIGYCPQQDALDELL-- 4783
Cdd:NF040873    7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAG----------VLRPTSGTV----RRAGGARVAYVPQRSEVPDSLpl 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4784 -------TG-WEHLYYYCSLRGIPRQcipeVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSS 4855
Cdd:NF040873   73 tvrdlvaMGrWARRGLWRRLTRDDRA----AVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTT 148
                         170       180       190
                  ....*....|....*....|....*....|...
gi 767944871 4856 GMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEE 4888
Cdd:NF040873  149 GLDAESRERIIALLAEEHARGATVVVVTHDLEL 181
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
4699-4925 3.54e-19

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 92.88  E-value: 3.54e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4699 RFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTtfKMLNGEVSltsGHAIIRTPMGDAVDLSSAGTAGVLIG-YCPQQD 4777
Cdd:NF000106   21 KHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**R--GALPAHV*---GPDAGRRPWRF*TWCANRRALRRTIG*HRPVR* 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4778 ALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGM 4857
Cdd:NF000106   96 GRRESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGL 175
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4858 DPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKNRFGdGYTVKV 4925
Cdd:NF000106  176 DPRTRNEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVG-GRTLQI 242
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
3928-4052 2.09e-14

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 78.24  E-value: 2.09e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3928 DNLTVREHLLLFAsiKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVD 4007
Cdd:NF000106   99 ESFSGRENLYMIG--R*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLD 176
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 767944871 4008 PCSRHSLWD-ILLKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:NF000106  177 PRTRNEVWDeVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRV 222
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
4690-4918 5.34e-13

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 75.93  E-value: 5.34e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4690 LYNLSKHYRRffqnIIAVQDISLGIPKGECFGLLGVNGAGKSTTFkmlngevSLTSGHAIIRT--------PMGDAVDLS 4761
Cdd:NF033858    4 LEGVSHRYGK----TVALDDVSLDIPAGCMVGLIGPDGVGKSSLL-------SLIAGARKIQQgrvevlggDMADARHRR 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4762 SAGTAgvlIGYCPQQdaldeL-------LTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRK 4834
Cdd:NF033858   73 AVCPR---IAYMPQG-----LgknlyptLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQK 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4835 LSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTI--MKEVREGcAAVLTSHS-MEECEAlCTRLAIMVNGsfKCL--GS 4909
Cdd:NF033858  145 LGLCCALIHDPDLLILDEPTTGVDPLSRRQFWELIdrIRAERPG-MSVLVATAyMEEAER-FDWLVAMDAG--RVLatGT 220

                  ....*....
gi 767944871 4910 PQHIKNRFG 4918
Cdd:NF033858  221 PAELLARTG 229
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
7-82 1.66e-11

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 71.58  E-value: 1.66e-11
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871     7 QFKALLWKNWLCRLRNPVLFLAEFFWPCILFVILTVLRFQEPPRYRDICYLQPRDLPSCGVIPFVQSLLCNTGSRC 82
Cdd:TIGR01257    6 QIQLLLWKNWTLRKRQKIRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPC 81
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
3842-4066 1.80e-11

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 70.92  E-value: 1.80e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIIngknLQTDLSRVRMELGVCP 3921
Cdd:NF033858    2 ARLEGVSHRY-GKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEV----LGGDMADARHRRAVCP 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QqdI----------LLDNLTVREHLLLFA-----SikapqwtKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSL 3986
Cdd:NF033858   77 R--IaympqglgknLYPTLSVFENLDFFGrlfgqD-------AAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGL 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3987 GIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGR---TIIFTTHHLDEAEALsDRVAVLQHGRLRCCGPPFCLKE 4063
Cdd:NF033858  148 CCALIHDPDLLILDEPTTGVDPLSRRQFWELIDRIRAERpgmSVLVATAYMEEAERF-DWLVAMDAGRVLATGTPAELLA 226

                  ...
gi 767944871 4064 AYG 4066
Cdd:NF033858  227 RTG 229
GguA NF040905
sugar ABC transporter ATP-binding protein;
3846-4051 7.98e-09

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 61.73  E-value: 7.98e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3846 SVTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTS--GTIIINGKNLQ-TDLSR--------VR 3914
Cdd:NF040905    6 GITKTFPGVKAL-DDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHGSyeGEILFDGEVCRfKDIRDsealgiviIH 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3915 MELGVCPQqdilldnLTVREHLLL---FASIKAPQWtkKELHQQVNQTLQDVDLtqHQHKQTRALSGGL-KRKLsLGIAf 3990
Cdd:NF040905   85 QELALIPY-------LSIAENIFLgneRAKRGVIDW--NETNRRARELLAKVGL--DESPDTLVTDIGVgKQQL-VEIA- 151
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 3991 MGMSRTV---VLDEPTSGV-DPCSRHsLWDILLKYRE-GRTIIFTTHHLDEAEALSDRVAVLQHGR 4051
Cdd:NF040905  152 KALSKDVkllILDEPTAALnEEDSAA-LLDLLLELKAqGITSIIISHKLNEIRRVADSITVLRDGR 216
GguA NF040905
sugar ABC transporter ATP-binding protein;
4707-4904 2.31e-03

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 44.01  E-value: 2.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGECFGLLGVNGAGKsTTFKMlngevSL--------TSGHAIIRtpmGDAVDLSS------AGTAGV---- 4768
Cdd:NF040905  276 VDDVSLNVRRGEIVGIAGLMGAGR-TELAM-----SVfgrsygrnISGTVFKD---GKEVDVSTvsdaidAGLAYVtedr 346
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4769 ------LIgycpqqDALDELLTGwehlyyyCSLRGI-PRQCIPE-----VAGDLIRRLHLEAHA-DKPVATYSGGTKRKL 4835
Cdd:NF040905  347 kgyglnLI------DDIKRNITL-------ANLGKVsRRGVIDEneeikVAEEYRKKMNIKTPSvFQKVGNLSGGNQQKV 413
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4836 STALALVGKPDILLLDEPSSGMDPCSKrYLWQTIMKE-VREGCAAVLTSHSMEECEALCTRLAIMVNGSF 4904
Cdd:NF040905  414 VLSKWLFTDPDVLILDEPTRGIDVGAK-YEIYTIINElAAEGKGVIVISSELPELLGMCDRIYVMNEGRI 482
 
Name Accession Description Interval E-value
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
3068-5018 0e+00

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 1064.24  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3068 VKIKDLMKNITKLTEELRSSIQISNETIHSILEANISHSKVLFSALTVALSG-KCDQEILHLLLTFPKGEKSWIAAEELC 3146
Cdd:TIGR01257  151 IRIRDILKDEEALTLFLMKNIGLSDSVVYLLVNSQVRPEQFAYGVPDLELKDiACSEALLERFIIFSQRRGAQTVRDALC 230
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3147 SLPGSKVYSLIVLLSRNLDV-RAF-IYKTLMPSEANGL-LNSLLDIVSSLSALLAKaqhvFEYLPEFLHTFKIT-ALLET 3222
Cdd:TIGR01257  231 SLSQGTLQWIEDTLYANVDFfKLFhVLPTLLDSRSQGInLRSWGGILSDMSPRIQE----FIHRPSVQDLLWVTrPLLQN 306
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3223 LDFQQVSQNVQARSSAF-------GSFQFVMkmvckdqaSFLSDSNMfinlprvKELLEDDKEK----FNIPEDSTPFCL 3291
Cdd:TIGR01257  307 GGPETFTQLMGILSDLLcgypeggGSRVFSF--------NWYEDNNY-------KAFLGIDSTRkdpiYSYDKRTTSFCN 371
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3292 KLYQEILQLPNGALVWTFLKPILHGKILYTPNTPEINKVIQKANYTFYIVDKLKTLSETLLEMSS----LFQRSGsgQMf 3367
Cdd:TIGR01257  372 ALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARRILKNANSTFEELERVRKLVKAWEEVGPqiwyFFDKST--QM- 448
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3368 NQLQEALRNKFVRNFVENQLH---IDVDKLTEKLQT--YGGLLDEMFNHAGAGRF----RFLGsiLVN-LSSCVALNRFQ 3437
Cdd:TIGR01257  449 TMIRDTLQNPTVKDFINRQLGeegITAEAVLNFLYNgpREKQADDMTNFDWRDIFnitdRFLR--LANqYLECLVLDKFE 526
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3438 ALQSVDILETKAHELLQQNSFLASIIFSNslfdknFRSESVKLPPHVSYTIRTNVLYSVRTDVVKNPSWKFHPQNLPADG 3517
Cdd:TIGR01257  527 SYDDEVQLTQRALSLLEENRFWAGVVFPD------MYPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVED 600
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3518 FKYNYV-FAPLQDMIERAIILVQTgQEALEPAAQTQAAPYPCHTSDLFLNNVGFFFPLIMMLTWMVSVASMVRKLVYEQE 3596
Cdd:TIGR01257  601 FRYIWGgFAYLQDMVEQGITRSQM-QAEPPVGIYLQQMPYPCFVDDSFMIILNRCFPIFMVLAWIYSVSMTVKSIVLEKE 679
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3597 IQIEEYMRMMGVHPVIHFLAWFLENMAVLTISSATLAIVLKTSGIFAHSNTFIVFLFLLDFGMSVVMLSYLLSAFFSQAN 3676
Cdd:TIGR01257  680 LRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGRILHYSDPFILFLFLLAFSTATIMQCFLLSTFFSKAS 759
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3677 TAALCTSLVYMISFLPYIVLLVLHNQLSFVNQTFLCLLSTTAFGQGVFFITFLEGQETGIQWNNMYQA-LEQGGMTFGWV 3755
Cdd:TIGR01257  760 LAAACSGVIYFTLYLPHILCFAWQDRMTADLKTAVSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSpLEGDEFSFLLS 839
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3756 CWMILFDSSLYFLCGWYLSNLIPGTFGLRKPWYFPFTASYWKSVGFLVEKRQYFLSSSLFFFNENFDNKGSSLQNR---E 3832
Cdd:TIGR01257  840 MKMMLLDAALYGLLAWYLDQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTEPLTEEMEDPEHPEGINDsffE 919
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3833 GELEGSAPGVTLVSVTKEYEGH-KAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLS 3911
Cdd:TIGR01257  920 RELPGLVPGVCVKNLVKIFEPSgRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETNLD 999
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3912 RVRMELGVCPQQDILLDNLTVREHLLLFASIKAPQWTKKELhqQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFM 3991
Cdd:TIGR01257 1000 AVRQSLGMCPQHNILFHHLTVAEHILFYAQLKGRSWEEAQL--EMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFV 1077
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3992 GMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPFCLKEAYGQGLRL 4071
Cdd:TIGR01257 1078 GDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTPLFLKNCFGTGFYL 1157
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4072 TLTRQPSVLEAH------------------------DLK-------DMACVTSLIKIYIPQAFLKDSSGSELTYTIP-KD 4119
Cdd:TIGR01257 1158 TLVRKMKNIQSQrggcegtcsctskgfstrcparvdEITpeqvldgDVNELMDLVYHHVPEAKLVECIGQELIFLLPnKN 1237
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4120 TDKACLKGLFQALDENLHQLHLTGYGISDTTLEEVFLMLLQDSNKKSHIALGTESELQN---------------HRPTGH 4184
Cdd:TIGR01257 1238 FKQRAYASLFRELEETLADLGLSSFGISDTPLEEIFLKVTEDADSGSLFAGGAQQKRENanlrhpcsgptekagQTPQAS 1317
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4185 LSGYCGSLARPATVQ--------------GVQLLRAQVAAILARRLRRTLRAGKSTLADLLLPVLFVALAMGLFMVRPLA 4250
Cdd:TIGR01257 1318 HTCSPGQPAAHPEGQpppepedpgvplntGARLILQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIIIPPF 1397
                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4251 TEYPPLRLTPGHYQRAETYF-FSSSGGDNLD-LTRVLLRK--FRDQ--------DLPCAdlnprqkNSSCWRTdPFSHPE 4318
Cdd:TIGR01257 1398 GEYPALTLHPWMYGQQYTFFsMDEPNSEHLEvLADVLLNKpgFGNRclkeewlpEYPCG-------NSTPWKT-PSVSPN 1469
                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4319 ----FQD----------SCGCL---------KCPNRSAS--APYLTNHLGHTLLNLSGFNMEEYLLA--PS--------- 4362
Cdd:TIGR01257 1470 ithlFQKqkwtaahpspSCRCStrekltmlpECPEGAGGlpPPQRTQRSTEILQDLTDRNISDFLVKtyPAlirsslksk 1549
                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4363 ---EKPRLGGWSFGLKIPS-----EA-------GGANGNISKPPTL-------------------AKVWYNQKGFHSLPS 4408
Cdd:TIGR01257 1550 fwvNEQRYGGISIGGKLPAipitgEAlvgflsdLGQMMNVSGGPVTreaskempdflkhletednIKVWFNNKGWHALVS 1629
                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4409 YLNHLNNLILWQHLPPTVDWRQYGITLYSHPYG--GALLNEDKILESIRQCGVALCIVLGFSILSASI------------ 4474
Cdd:TIGR01257 1630 FLNVAHNAILRASLPKDRDPEEYGITVISQPLNltKEQLSEITVLTTSVDAVVAICVIFAMSFVPASFvlyliqervnka 1709
                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4475 -------GSS------------VLFYLVSVCLCVAVIVAFQLTAFTFRKNLAATALLLSLFGYATLPWMYLMSRIFSSSD 4535
Cdd:TIGR01257 1710 khlqfisGVSpttywltnflwdIMNYAVSAGLVVGIFIGFQKKAYTSPENLPALVALLMLYGWAVIPMMYPASFLFDVPS 1789
                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4536 VAFISYVSLNFIFGLCTMLITImprLLAIISKAKNLQNIYDVLKWVFTIFPQFCLGQGLVELCYNQIKYDLTHNFGIDSY 4615
Cdd:TIGR01257 1790 TAYVALSCANLFIGINSSAITF---VLELFENNRTLLRFNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDVYAQFGEEHS 1866
                         1770      1780      1790      1800      1810      1820      1830      1840
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4616 VSPFEMNFLGWIFVQLASQGTV--LLLLRVLLHWDLLRWPrGHSTLQGTVksSKDTDVEKEEKRVFEGRTNGDILVLYNL 4693
Cdd:TIGR01257 1867 ANPFQWDLIGKNLVAMAVEGVVyfLLTLLIQHHFFLSRWI-AEPAKEPIF--DEDDDVAEERQRIISGGNKTDILRLNEL 1943
                         1850      1860      1870      1880      1890      1900      1910      1920
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4694 SKHYRRffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAiirTPMGDAVdLSSAGTAGVLIGYC 4773
Cdd:TIGR01257 1944 TKVYSG--TSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDA---TVAGKSI-LTNISDVHQNMGYC 2017
                         1930      1940      1950      1960      1970      1980      1990      2000
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4774 PQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEP 4853
Cdd:TIGR01257 2018 PQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEP 2097
                         2010      2020      2030      2040      2050      2060      2070      2080
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4854 SSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKNRFGDGYTVKVWLCKEANQ 4933
Cdd:TIGR01257 2098 TTGMDPQARRMLWNTIVSIIREGRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGTIQHLKSKFGDGYIVTMKIKSPKDD 2177
                         2090      2100      2110      2120      2130      2140      2150      2160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4934 HC----TVSDHLKLYFPGIQFKGQHLNLLEYHVPKrwGCLADLFKVIENNKTFLNIKHYSINQTTLEQVFINFASEQQQT 5009
Cdd:TIGR01257 2178 LLpdlnPVEQFFQGNFPGSVQRERHYNMLQFQVSS--SSLARIFQLLISHKDSLLIEEYSVTQTTLDQVFVNFAKQQTET 2255

                   ....*....
gi 767944871  5010 LQSTLDPST 5018
Cdd:TIGR01257 2256 YDLPLHPRA 2264
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
4688-4914 1.38e-94

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 305.97  E-value: 1.38e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYRRFFQniIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmgDAVDLSSAGTAG 4767
Cdd:cd03263     1 LQIRNLTKTYKKGTK--PAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYIN----GYSIRTDRKAAR 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4768 VLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDI 4847
Cdd:cd03263    75 QSLGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSV 154
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4848 LLLDEPSSGMDPCSKRYLWQTImKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIK 4914
Cdd:cd03263   155 LLLDEPTSGLDPASRRAIWDLI-LEVRKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
3842-4062 5.43e-93

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 301.73  E-value: 5.43e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYE-GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVC 3920
Cdd:cd03263     1 LQIRNLTKTYKkGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAARQSLGYC 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3921 PQQDILLDNLTVREHLLLFASIKAPqwTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLD 4000
Cdd:cd03263    81 PQFDALFDELTVREHLRFYARLKGL--PKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLD 158
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4001 EPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPFCLK 4062
Cdd:cd03263   159 EPTSGLDPASRRAIWDLILEVRKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
3842-4058 5.88e-77

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 256.14  E-value: 5.88e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCP 3921
Cdd:COG1131     1 IEVRGLTKRYGDKTAL-DGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEVRRRIGYVP 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QQDILLDNLTVREHLLLFASIKapQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDE 4001
Cdd:COG1131    80 QEPALYPDLTVRENLRFFARLY--GLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDE 157
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4002 PTSGVDPCSRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:COG1131   158 PTSGLDPEARRELWELLRELAaEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTP 215
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
4692-4917 2.47e-74

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 248.83  E-value: 2.47e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRFfqniIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAII--RTPMGDAVDLSSagtagvL 4769
Cdd:COG1131     5 GLTKRYGDK----TALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVlgEDVARDPAEVRR------R 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4770 IGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILL 4849
Cdd:COG1131    75 IGYVPQEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLI 154
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4850 LDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKNRF 4917
Cdd:COG1131   155 LDEPTSGLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKARL 222
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
3842-4052 3.89e-60

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 205.32  E-value: 3.89e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCP 3921
Cdd:cd03230     1 IEVRNLSKRY-GKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEVKRRIGYLP 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QQDILLDNLTVREHLLlfasikapqwtkkelhqqvnqtlqdvdltqhqhkqtraLSGGLKRKLSLGIAFMGMSRTVVLDE 4001
Cdd:cd03230    80 EEPSLYENLTVRENLK--------------------------------------LSGGMKQRLALAQALLHDPELLILDE 121
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4002 PTSGVDPCSRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:cd03230   122 PTSGLDPESRREFWELLRELKkEGKTILLSSHILEEAERLCDRVAILNNGRI 173
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
3843-4067 9.79e-57

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 198.54  E-value: 9.79e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3843 TLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCPQ 3922
Cdd:COG4555     3 EVENLSKKY-GKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPREARRQIGVLPD 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3923 QDILLDNLTVREHLLLFASIKapQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEP 4002
Cdd:COG4555    82 ERGLYDRLTVRENIRYFAELY--GLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEP 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 4003 TSGVDPCSRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPFCLKEAYGQ 4067
Cdd:COG4555   160 TNGLDVMARRLLREILRALKkEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGE 225
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
4692-4914 9.43e-55

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 191.81  E-value: 9.43e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRFfqniIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpMGDAVdLSSAGTAGVLIG 4771
Cdd:cd03265     5 NLVKKYGDF----EAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATV---AGHDV-VREPREVRRRIG 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4772 YCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLD 4851
Cdd:cd03265    77 IVFQDLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLD 156
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 4852 EPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIK 4914
Cdd:cd03265   157 EPTIGLDPQTRAHVWEYIEKLKEEfGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEELK 220
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
3847-4062 4.97e-54

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 189.89  E-value: 4.97e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCPQQDIL 3926
Cdd:cd03265     6 LVKKYGDFEAV-RGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPREVRRRIGIVFQDLSV 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3927 LDNLTVREHLLLFASIKAPQWtkKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGV 4006
Cdd:cd03265    85 DDELTGWENLYIHARLYGVPG--AERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGL 162
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4007 DPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPFCLK 4062
Cdd:cd03265   163 DPQTRAHVWEYIekLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEELK 220
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
4692-4902 1.52e-51

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 180.67  E-value: 1.52e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRFfqniIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGT-AGVLI 4770
Cdd:cd03230     5 NLSKRYGKK----TALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKV-----LGKDIKKEPEeVKRRI 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4771 GYCPQQDALDELLTGWEHLYYycslrgiprqcipevagdlirrlhleahadkpvatySGGTKRKLSTALALVGKPDILLL 4850
Cdd:cd03230    76 GYLPEEPSLYENLTVRENLKL------------------------------------SGGMKQRLALAQALLHDPELLIL 119
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4851 DEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:cd03230   120 DEPTSGLDPESRREFWELLRELKKEGKTILLSSHILEEAERLCDRVAILNNG 171
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
4692-4919 7.24e-51

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 181.59  E-value: 7.24e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRFFqniiAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAgVL-- 4769
Cdd:COG4555     6 NLSKKYGKVP----ALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILI-----DGEDVRKEPRE-ARrq 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4770 IGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILL 4849
Cdd:COG4555    76 IGVLPDERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLL 155
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4850 LDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKNRFGD 4919
Cdd:COG4555   156 LDEPTNGLDVMARRLLREILRALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGE 225
drrA TIGR01188
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...
3849-4158 2.50e-50

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]


Pssm-ID: 130256 [Multi-domain]  Cd Length: 302  Bit Score: 182.20  E-value: 2.50e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3849 KEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCPQQDILLD 3928
Cdd:TIGR01188    1 KVYGDFKAV-DGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGYDVVREPRKVRRSIGIVPQYASVDE 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3929 NLTVREHLLLFASIKApqWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDP 4008
Cdd:TIGR01188   80 DLTGRENLEMMGRLYG--LPKDEAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDP 157
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4009 CSRHSLWDILLKYRE-GRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPfclkeaygQGLRLTLTRQPSVLEAHDLKD 4087
Cdd:TIGR01188  158 RTRRAIWDYIRALKEeGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTP--------EELKRRLGKDTLESRPRDIQS 229
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4088 MACVTSLIKIYIPQAFLKDSSgseltytIPKDTDKA---------CLKGLFQALDENlhQLHLTGYGISDTTLEEVFLML 4158
Cdd:TIGR01188  230 LKVEVSMLIAELGETGLGLLA-------VTVDSDRIkilvpdgdeTVPEIVEAAIRN--GIRIRSISTERPSLDDVFLKL 300
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
3847-4058 2.23e-47

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 170.98  E-value: 2.23e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL-QTDLSRVRMELGVCPQQ-D 3924
Cdd:COG1122     6 LSFSYPGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDItKKNLRELRRKVGLVFQNpD 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3925 ILLDNLTVREHLLLfasikAPQ---WTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSL-GIAFMGmSRTVVLD 4000
Cdd:COG1122    86 DQLFAPTVEEDVAF-----GPEnlgLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIaGVLAME-PEVLVLD 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 4001 EPTSGVDPCSRHSLWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:COG1122   160 EPTAGLDPRGRRELLELLKRLnKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTP 218
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
3842-4056 2.37e-45

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 164.67  E-value: 2.37e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYeGHKAVVQDLSLTFyRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCP 3921
Cdd:cd03264     1 LQLENLTKRY-GKKRALDGVSLTL-GPGMYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKLRRRIGYLP 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QQDILLDNLTVREHLLLFASIKApqWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDE 4001
Cdd:cd03264    79 QEFGVYPNFTVREFLDYIAWLKG--IPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDE 156
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4002 PTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCG 4056
Cdd:cd03264   157 PTAGLDPEERIRFRNLLSELGEDRIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
3842-4163 9.69e-45

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 166.05  E-value: 9.69e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDlsrVRMELGVCP 3921
Cdd:COG4152     2 LELKGLTKRFGDKTAV-DDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPE---DRRRIGYLP 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QQDILLDNLTVREHLLLFASIKapQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDE 4001
Cdd:COG4152    78 EERGLYPKMKVGEQLVYLARLK--GLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLILDE 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4002 PTSGVDPCSRHSLWDILLKYRE-GRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPFCLKEAYG-QGLRLTLTRQPSV 4079
Cdd:COG4152   156 PFSGLDPVNVELLKDVIRELAAkGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQFGrNTLRLEADGDAGW 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4080 LEAhdlkdmacvtslikiyIPQAFLKDSSGSELTYTIPKDTDKaclKGLFQALdenLHQLHLTGYGISDTTLEEVFLMLL 4159
Cdd:COG4152   236 LRA----------------LPGVTVVEEDGDGAELKLEDGADA---QELLRAL---LARGPVREFEEVRPSLNEIFIEVV 293

                  ....
gi 767944871 4160 QDSN 4163
Cdd:COG4152   294 GEKA 297
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
3847-4053 1.57e-44

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 162.00  E-value: 1.57e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQtDLSRVRMELGVCPQQDIL 3926
Cdd:cd03268     6 LTKTY-GKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQ-KNIEALRRIGALIEAPGF 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3927 LDNLTVREHLLLFAsiKAPQWTKKElhqqVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGV 4006
Cdd:cd03268    84 YPNLTARENLRLLA--RLLGIRKKR----IDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNGL 157
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 767944871 4007 DPCSRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVLQHGRLR 4053
Cdd:cd03268   158 DPDGIKELRELILSLRdQGITVLISSHLLSEIQKVADRIGIINKGKLI 205
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
3847-4058 2.94e-44

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 163.29  E-value: 2.94e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLS---RVRMelGVC--- 3920
Cdd:COG0411    10 LTKRFGGLVAV-DDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDI-TGLPphrIARL--GIArtf 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3921 --PQqdiLLDNLTVREHLLL----------FASIKAPQWTKK---ELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLS 3985
Cdd:COG0411    86 qnPR---LFPELTVLENVLVaaharlgrglLAALLRLPRARReerEARERAEELLERVGLADRADEPAGNLSYGQQRRLE 162
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 3986 LGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYRE--GRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:COG0411   163 IARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDerGITILLIEHDMDLVMGLADRIVVLDFGRVIAEGTP 237
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
3838-4071 4.26e-44

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 162.18  E-value: 4.26e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3838 SAPGVTLVSVTKEYEGHKaVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVrmel 3917
Cdd:COG1121     3 MMPAIELENLTVSYGGRP-VLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRARRRI---- 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3918 GVCPQQDILLDN--LTVREHLL--LFASIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGM 3993
Cdd:COG1121    78 GYVPQRAEVDWDfpITVRDVVLmgRYGRRGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQD 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3994 SRTVVLDEPTSGVDPCSRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVLQHGRLrCCGPP------FCLKEAYG 4066
Cdd:COG1121   158 PDLLLLDEPFAGVDAATEEALYELLRELRrEGKTILVVTHDLGAVREYFDRVLLLNRGLV-AHGPPeevltpENLSRAYG 236

                  ....*
gi 767944871 4067 QGLRL 4071
Cdd:COG1121   237 GPVAL 241
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
4688-4903 1.23e-43

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 159.69  E-value: 1.23e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKhyrrFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPmgDAVDLSSA-GTA 4766
Cdd:cd03268     1 LKTNDLTK----TYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGK--SYQKNIEAlRRI 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4767 GVLIGYcPqqdALDELLTGWEHLYYYCSLRGIPRQCIPEVagdlIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPD 4846
Cdd:cd03268    75 GALIEA-P---GFYPNLTARENLRLLARLLGIRKKRIDEV----LDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPD 146
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4847 ILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGS 4903
Cdd:cd03268   147 LLILDEPTNGLDPDGIKELRELILSLRDQGITVLISSHLLSEIQKVADRIGIINKGK 203
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
3853-4058 1.77e-43

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 160.98  E-value: 1.77e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLSR--VRMELGVCPQQDILLDNL 3930
Cdd:COG1120    12 GGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDL-ASLSRreLARRIAYVPQEPPAPFGL 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3931 TVREHLLL--FASIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDP 4008
Cdd:COG1120    91 TVRELVALgrYPHLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLLLDEPTSHLDL 170
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4009 CSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:COG1120   171 AHQLEVLELLrrLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPP 222
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
3847-4056 2.27e-43

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 158.98  E-value: 2.27e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDlsrVRMELGVCPQQDIL 3926
Cdd:cd03269     6 VTKRF-GRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIA---ARNRIGYLPEERGL 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3927 LDNLTVREHLLLFASIKApqWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGV 4006
Cdd:cd03269    82 YPKMKVIDQLVYLAQLKG--LKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGL 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4007 DPCSRHSLWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCG 4056
Cdd:cd03269   160 DPVNVELLKDVIRELaRAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
4688-4905 1.26e-42

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 156.97  E-value: 1.26e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYRRffqnIIAVQDISLGIPKGeCFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAG 4767
Cdd:cd03264     1 LQLENLTKRYGK----KRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRI-----DGQDVLKQPQKL 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4768 -VLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPD 4846
Cdd:cd03264    71 rRRIGYLPQEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPS 150
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 4847 ILLLDEPSSGMDPcSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFK 4905
Cdd:cd03264   151 ILIVDEPTAGLDP-EERIRFRNLLSELGEDRIVILSTHIVEDVESLCNQVAVLNKGKLV 208
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
3847-4058 2.58e-42

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 156.83  E-value: 2.58e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLS---RVRMELGVCPQQ 3923
Cdd:cd03219     6 LTKRFGGLVAL-DDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDI-TGLPpheIARLGIGRTFQI 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3924 DILLDNLTVREHLLL--------FASIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSR 3995
Cdd:cd03219    84 PRLFPELTVLENVMVaaqartgsGLLLARARREEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALATDPK 163
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 3996 TVVLDEPTSGVDPCSRHSLWDILLKYRE-GRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:cd03219   164 LLLLDEPAAGLNPEETEELAELIRELRErGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTP 227
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
4692-4902 7.47e-42

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 154.83  E-value: 7.47e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGVL-I 4770
Cdd:cd03266     6 ALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATV-----DGFDVVKEPAEARRrL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4771 GYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLL 4850
Cdd:cd03266    81 GFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLL 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4851 DEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:cd03266   161 DEPTTGLDVMATRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRG 212
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
4692-4902 1.54e-41

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 153.59  E-value: 1.54e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRffqnIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIR-TPMGDAvdlssagtAGVLI 4770
Cdd:cd03269     5 NVTKRFGR----VTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDgKPLDIA--------ARNRI 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4771 GYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLL 4850
Cdd:cd03269    73 GYLPEERGLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLIL 152
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4851 DEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:cd03269   153 DEPFSGLDPVNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKG 204
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
3820-4061 1.77e-41

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 158.07  E-value: 1.77e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3820 NFDNKGSSLQNREGELEGSAPGVT--LVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSG 3897
Cdd:PRK13536   18 PIERKHQGISEAKASIPGSMSTVAidLAGVSKSY-GDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAG 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3898 TIIINGKNLQTDLSRVRMELGVCPQQDILLDNLTVREHLLLFAsiKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALS 3977
Cdd:PRK13536   97 KITVLGVPVPARARLARARIGVVPQFDNLDLEFTVRENLLVFG--RYFGMSTREIEAVIPSLLEFARLESKADARVSDLS 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3978 GGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDIL--LKYReGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCC 4055
Cdd:PRK13536  175 GGMKRRLTLARALINDPQLLILDEPTTGLDPHARHLIWERLrsLLAR-GKTILLTTHFMEEAERLCDRLCVLEAGRKIAE 253

                  ....*.
gi 767944871 4056 GPPFCL 4061
Cdd:PRK13536  254 GRPHAL 259
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
3838-4058 1.88e-41

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 154.37  E-value: 1.88e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3838 SAPGVTLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT----DLSRV 3913
Cdd:COG1127     2 SEPMIEVRNLTKSF-GDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGlsekELYEL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3914 RMELGVCPQQDILLDNLTV--------REHLLLfasikapqwTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLs 3985
Cdd:COG1127    81 RRRIGMLFQGGALFDSLTVfenvafplREHTDL---------SEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRV- 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3986 lGIAfmgmsRTVVL-------DEPTSGVDPCSRHSLWDILLKYRE--GRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCG 4056
Cdd:COG1127   151 -ALA-----RALALdpeillyDEPTAGLDPITSAVIDELIRELRDelGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEG 224

                  ..
gi 767944871 4057 PP 4058
Cdd:COG1127   225 TP 226
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
3837-4064 5.42e-41

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 155.73  E-value: 5.42e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3837 GSAPGVTLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRME 3916
Cdd:PRK13537    3 MSVAPIDFRNVEKRY-GDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHARQR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3917 LGVCPQQDILLDNLTVREHLLLFAsiKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRT 3996
Cdd:PRK13537   82 VGVVPQFDNLDPDFTVRENLLVFG--RYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDV 159
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3997 VVLDEPTSGVDPCSRHSLWDIL--LKYReGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPFCLKEA 4064
Cdd:PRK13537  160 LVLDEPTTGLDPQARHLMWERLrsLLAR-GKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALIES 228
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
3842-4047 1.40e-40

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 151.09  E-value: 1.40e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHKA---VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKnlqtDLSRVRMELG 3918
Cdd:cd03293     1 LEVRNVSKTYGGGGGavtALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGE----PVTGPGPDRG 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3919 VCPQQDILLDNLTVREHLLLfaSIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVV 3998
Cdd:cd03293    77 YVFQQDALLPWLTVLDNVAL--GLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLL 154
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767944871 3999 LDEPTSGVDPCSRHSLWDILLK--YREGRTIIFTTHHLDEAEALSDRVAVL 4047
Cdd:cd03293   155 LDEPFSALDALTREQLQEELLDiwRETGKTVLLVTHDIDEAVFLADRVVVL 205
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
3840-4039 5.85e-40

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 148.78  E-value: 5.85e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3840 PGVTLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGV 3919
Cdd:COG4133     1 MMLEAENLSCRR-GERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREDYRRRLAY 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3920 CPQQDILLDNLTVREHLLLFASIKAPQWTkkelHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVL 3999
Cdd:COG4133    80 LGHADGLKPELTVRENLRFWAALYGLRAD----REAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLL 155
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 767944871 4000 DEPTSGVDPCSRHSLWDILLKYRE-GRTIIFTTHHLDEAEA 4039
Cdd:COG4133   156 DEPFTALDAAGVALLAELIAAHLArGGAVLLTTHQPLELAA 196
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
4687-4918 1.17e-39

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 151.41  E-value: 1.17e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYRRFfqniIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTa 4766
Cdd:COG4152     1 MLELKGLTKRFGDK----TAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWD---GEPLDPEDRRR- 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4767 gvlIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPD 4846
Cdd:COG4152    73 ---IGYLPEERGLYPKMKVGEQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPE 149
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4847 ILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKNRFG 4918
Cdd:COG4152   150 LLILDEPFSGLDPVNVELLKDVIRELAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQFG 221
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
3847-4058 1.54e-39

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 148.80  E-value: 1.54e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL----QTDLSRVRMELGVCPQ 3922
Cdd:cd03261     6 LTKSF-GGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDIsglsEAELYRLRRRMGMLFQ 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3923 QDILLDNLTV--------REHLLLfasikapqwTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMS 3994
Cdd:cd03261    85 SGALFDSLTVfenvafplREHTRL---------SEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDP 155
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 3995 RTVVLDEPTSGVDPCSRHSLWDILLKYRE--GRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:cd03261   156 ELLLYDEPTAGLDPIASGVIDDLIRSLKKelGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTP 221
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
3844-4051 3.15e-39

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 146.84  E-value: 3.15e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3844 LVSVTKEYEGH-KAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL-QTDLSRVRMELGVCP 3921
Cdd:cd03225     2 LKNLSFSYPDGaRPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLtKLSLKELRRKVGLVF 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QQ-DILLDNLTVREHLLLfaSIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLD 4000
Cdd:cd03225    82 QNpDDQFFGPTVEEEVAF--GLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLD 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4001 EPTSGVDPCSRHSLWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVLQHGR 4051
Cdd:cd03225   160 EPTAGLDPAGRRELLELLKKLkAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
3837-4047 3.36e-39

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 148.70  E-value: 3.36e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3837 GSAPGVTLVSVTKEY---EGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKnlqtDLSRV 3913
Cdd:COG1116     3 AAAPALELRGVSKRFptgGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGK----PVTGP 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3914 RMELGVCPQQDILLDNLTVREHLLLfaSIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGM 3993
Cdd:COG1116    79 GPDRGVVFQEPALLPWLTVLDNVAL--GLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALAND 156
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 3994 SRTVVLDEPTSGVDPCSRHSLWDILLKY--REGRTIIFTTHHLDEAEALSDRVAVL 4047
Cdd:COG1116   157 PEVLLMDEPFGALDALTRERLQDELLRLwqETGKTVLFVTHDVDEAVFLADRVVVL 212
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
3847-4047 3.93e-38

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 143.83  E-value: 3.93e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKaVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVrmelGVCPQQ-DI 3925
Cdd:cd03235     5 LTVSYGGHP-VLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKERKRI----GYVPQRrSI 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3926 LLD-NLTVREHLL--LFASIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEP 4002
Cdd:cd03235    80 DRDfPISVRDVVLmgLYGHKGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEP 159
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 767944871 4003 TSGVDPCSRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVL 4047
Cdd:cd03235   160 FAGVDPKTQEDIYELLRELRrEGMTILVVTHDLGLVLEYFDRVLLL 205
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
4698-4911 8.39e-38

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 147.28  E-value: 8.39e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4698 RRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAiirTPMGDAVDlSSAGTAGVLIGYCPQQD 4777
Cdd:PRK13536   48 SKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKI---TVLGVPVP-ARARLARARIGVVPQFD 123
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4778 ALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGM 4857
Cdd:PRK13536  124 NLDLEFTVRENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDEPTTGL 203
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 767944871 4858 DPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQ 4911
Cdd:PRK13536  204 DPHARHLIWERLRSLLARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPH 257
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
3842-4058 1.59e-37

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 143.21  E-value: 1.59e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKN-LQTDLSRVRMELGVC 3920
Cdd:cd03295     1 IEFENVTKRYGGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDiREQDPVELRRKIGYV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3921 PQQDILLDNLTVREHLLLFASIKapQWTKKELHQQVNQTLQDVDL--TQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVV 3998
Cdd:cd03295    81 IQQIGLFPHMTVEENIALVPKLL--KWPKEKIRERADELLALVGLdpAEFADRYPHELSGGQQQRVGVARALAADPPLLL 158
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 3999 LDEPTSGVDPCSRHSLWDILLKYRE--GRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:cd03295   159 MDEPFGALDPITRDQLQEEFKRLQQelGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTP 220
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
4687-4911 1.71e-37

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 145.33  E-value: 1.71e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYrrffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGevsltsghaiIRTPMGDAVDL------ 4760
Cdd:PRK13537    7 PIDFRNVEKRY----GDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLG----------LTHPDAGSISLcgepvp 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4761 SSAGTAGVLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALA 4840
Cdd:PRK13537   73 SRARHARQRVGVVPQFDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARA 152
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4841 LVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQ 4911
Cdd:PRK13537  153 LVNDPDVLVLDEPTTGLDPQARHLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPH 223
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
3842-4056 1.75e-37

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 142.27  E-value: 1.75e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLSRVRMELGVCP 3921
Cdd:cd03259     1 LELKGLSKTY-GSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDV-TGVPPERRNIGMVF 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QQDILLDNLTVREHlLLFAsIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGiafmgmsRTVV--- 3998
Cdd:cd03259    79 QDYALFPHLTVAEN-IAFG-LKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALA-------RALArep 149
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 3999 ----LDEPTSGVDPCSRHSLWDILLKYRE--GRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCG 4056
Cdd:cd03259   150 slllLDEPLSALDAKLREELREELKELQRelGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
3842-4053 6.78e-37

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 140.58  E-value: 6.78e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYE---GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELG 3918
Cdd:cd03266     2 ITADALTKRFRdvkKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEPAEARRRLG 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3919 VCPQQDILLDNLTVREHLLLFASIKAPQwtKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVV 3998
Cdd:cd03266    82 FVSDSTGLYDRLTARENLEYFAGLYGLK--GDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLL 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 3999 LDEPTSGVDPCSRHSLWDILLKYRE-GRTIIFTTHHLDEAEALSDRVAVLQHGRLR 4053
Cdd:cd03266   160 LDEPTTGLDVMATRALREFIRQLRAlGKCILFSTHIMQEVERLCDRVVVLHRGRVV 215
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
3836-4058 1.17e-36

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 148.51  E-value: 1.17e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3836 EGSAPGVTLVSVTKEYEGHKA----VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT--- 3908
Cdd:COG1123   255 AAAEPLLEVRNLSKRYPVRGKggvrAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKlsr 334
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3909 -DLSRVRMELGVCPQ--QDILLDNLTVREHlLLFASIKAPQWTKKELHQQVNQTLQDVDL-TQHQHKQTRALSGGLKRKL 3984
Cdd:COG1123   335 rSLRELRRRVQMVFQdpYSSLNPRMTVGDI-IAEPLRLHGLLSRAERRERVAELLERVGLpPDLADRYPHELSGGQRQRV 413
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 3985 SLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYRE--GRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:COG1123   414 AIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRelGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPT 489
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
3843-4051 1.71e-36

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 136.99  E-value: 1.71e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3843 TLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL-QTDLSRVRMELGVCP 3921
Cdd:cd00267     1 EIENLSFRY-GGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIaKLPLEELRRRIGYVP 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QqdilldnltvrehlllfasikapqwtkkelhqqvnqtlqdvdltqhqhkqtraLSGGLKRKLSLGIAFMGMSRTVVLDE 4001
Cdd:cd00267    80 Q-----------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDE 106
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4002 PTSGVDPCSRHSLWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVLQHGR 4051
Cdd:cd00267   107 PTSGLDPASRERLLELLRELaEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
4683-4913 3.67e-36

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 139.45  E-value: 3.67e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4683 TNGDILVLYNLSKHYRRffqnIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHaiIRtpmgdaVDLSS 4762
Cdd:COG1121     2 MMMPAIELENLTVSYGG----RPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGT--VR------LFGKP 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4763 AGTAGVLIGYCPQQDALDEL--LTGWE----HLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLS 4836
Cdd:COG1121    70 PRRARRRIGYVPQRAEVDWDfpITVRDvvlmGRYGRRGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVL 149
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4837 TALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLaIMVNGSFKCLGSPQHI 4913
Cdd:COG1121   150 LARALAQDPDLLLLDEPFAGVDAATEEALYELLRELRREGKTILVVTHDLGAVREYFDRV-LLLNRGLVAHGPPEEV 225
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
4692-4884 1.36e-35

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 136.45  E-value: 1.36e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHY--RRFFQniiavqDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTAGvL 4769
Cdd:COG4133     7 NLSCRRgeRLLFS------GLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWN---GEPIRDAREDYRR-R 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4770 IGYCPQQDALDELLTGWEHLYYYCSLRGIPRQciPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILL 4849
Cdd:COG4133    77 LAYLGHADGLKPELTVRENLRFWAALYGLRAD--REAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWL 154
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 767944871 4850 LDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSH 4884
Cdd:COG4133   155 LDEPFTALDAAGVALLAELIAAHLARGGAVLLTTH 189
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
3857-4058 2.20e-35

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 136.41  E-value: 2.20e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3857 VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLS---RVRMELGVCPQQDILLDNLTVR 3933
Cdd:cd03224    15 ILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDI-TGLPpheRARAGIGYVPEGRRIFPELTVE 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3934 EHLLLFASIKAPqwtkkelhQQVNQTLQDV-----DLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDP 4008
Cdd:cd03224    94 ENLLLGAYARRR--------AKRKARLERVyelfpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGLAP 165
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4009 CSRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:cd03224   166 KIVEEIFEAIRELRdEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTA 216
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
4706-4913 1.37e-34

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 134.38  E-value: 1.37e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGV--LIGYCPQQ-DA---- 4778
Cdd:COG1122    16 ALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLV-----DGKDITKKNLRELrrKVGLVFQNpDDqlfa 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4779 ---LDELLTGWEHLyyycslrGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSS 4855
Cdd:COG1122    91 ptvEEDVAFGPENL-------GLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLDEPTA 163
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4856 GMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:COG1122   164 GLDPRGRRELLELLKRLNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREV 221
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
3842-4051 2.86e-34

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 131.54  E-value: 2.86e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRV---RMELG 3918
Cdd:cd03229     1 LELKNVSKRY-GQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDELpplRRRIG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3919 VCPQQDILLDNLTVREHLLLfasikapqwtkkelhqqvnqtlqdvdltqhqhkqtrALSGGLKRKLSLGIAFMGMSRTVV 3998
Cdd:cd03229    80 MVFQDFALFPHLTVLENIAL------------------------------------GLSGGQQQRVALARALAMDPDVLL 123
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 3999 LDEPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGR 4051
Cdd:cd03229   124 LDEPTSALDPITRREVRALLksLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
4692-4902 3.31e-34

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 132.59  E-value: 3.31e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRFFQNIIavQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTAGVLIG 4771
Cdd:cd03225     4 NLSFSYPDGARPAL--DDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVD---GKDLTKLSLKELRRKVG 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4772 YCPQQ--------DALDELLTGWEHLyyycslrGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVG 4843
Cdd:cd03225    79 LVFQNpddqffgpTVEEEVAFGLENL-------GLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAM 151
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 4844 KPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:cd03225   152 DPDILLLDEPTAGLDPAGRRELLELLKKLKAEGKTIIIVTHDLDLLLELADRVIVLEDG 210
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
3842-4058 3.54e-34

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 133.44  E-value: 3.54e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHKaVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDL---SRVRMELG 3918
Cdd:cd03218     1 LRAENLSKRYGKRK-VVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDI-TKLpmhKRARLGIG 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3919 VCPQQDILLDNLTVREHLLLFASIKAPqwTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVV 3998
Cdd:cd03218    79 YLPQEASIFRKLTVEENILAVLEIRGL--SKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLL 156
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 3999 LDEPTSGVDPCSRHSLWDILLKYRE-GRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:cd03218   157 LDEPFAGVDPIAVQDIQKIIKILKDrGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTP 217
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
3847-4051 3.99e-34

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 130.97  E-value: 3.99e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEG-HKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT-DLSRVRMELGVCPQQD 3924
Cdd:cd03228     6 VSFSYPGrPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDlDLESLRKNIAYVPQDP 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3925 ILLdNLTVREHLllfasikapqwtkkelhqqvnqtlqdvdltqhqhkqtraLSGGLKRKLSLGIAFMGMSRTVVLDEPTS 4004
Cdd:cd03228    86 FLF-SGTIRENI---------------------------------------LSGGQRQRIAIARALLRDPPILILDEATS 125
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 767944871 4005 GVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEaLSDRVAVLQHGR 4051
Cdd:cd03228   126 ALDPETEALILEALRALAKGKTVIVIAHRLSTIR-DADRIIVLDDGR 171
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
3858-4004 1.06e-33

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 128.92  E-value: 1.06e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3858 VQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQ-TDLSRVRMELGVCPQQDILLDNLTVREHL 3936
Cdd:pfam00005    1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTdDERKSLRKEIGYVFQDPQLFPRLTVRENL 80
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871  3937 LLFASIKApqWTKKELHQQVNQTLQDVDLT----QHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTS 4004
Cdd:pfam00005   81 RLGLLLKG--LSKREKDARAEEALEKLGLGdladRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
3842-4052 1.11e-33

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 131.46  E-value: 1.11e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEG---HKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQ----TDLSRVR 3914
Cdd:cd03255     1 IELKNLSKTYGGggeKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISklseKELAAFR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3915 ME-LGVCPQQDILLDNLTVREHLLL---FASIKapqwtKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAF 3990
Cdd:cd03255    81 RRhIGFVFQSFNLLPDLTALENVELpllLAGVP-----KKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARAL 155
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 3991 MGMSRTVVLDEPTSGVDPCSRHSLWDILLKYRE--GRTIIFTTHHLDEAEaLSDRVAVLQHGRL 4052
Cdd:cd03255   156 ANDPKIILADEPTGNLDSETGKEVMELLRELNKeaGTTIVVVTHDPELAE-YADRIIELRDGKI 218
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
4688-4902 1.24e-33

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 131.10  E-value: 1.24e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYRrffqNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAG 4767
Cdd:cd03259     1 LELKGLSKTYG----SVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILI-----DGRDVTGVPPER 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4768 VLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDI 4847
Cdd:cd03259    72 RNIGMVFQDYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSL 151
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4848 LLLDEPSSGMDPCSKRYLwqtiMKEVRE-----GCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:cd03259   152 LLLDEPLSALDAKLREEL----REELKElqrelGITTIYVTHDQEEALALADRIAVMNEG 207
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
3838-4058 1.29e-33

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 135.61  E-value: 1.29e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3838 SAPGVTLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKnlqtDLSRVRME- 3916
Cdd:COG3842     2 AMPALELENVSKRY-GDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGR----DVTGLPPEk 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3917 --LGVCPQQDILLDNLTVREHLllfA-SIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLgiAfmgm 3993
Cdd:COG3842    77 rnVGMVFQDYALFPHLTVAENV---AfGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVAL--A---- 147
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 3994 sRTVV-------LDEPTSGVDPCSRHSLWDILLKY--REGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:COG3842   148 -RALApeprvllLDEPLSALDAKLREEMREELRRLqrELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTP 220
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
3849-4056 1.35e-33

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 131.24  E-value: 1.35e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3849 KEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGL---HPPTSGTIIINGKNLQTDLsrVRMELGVCPQQDI 3925
Cdd:cd03234    14 KNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRvegGGTTSGQILFNGQPRKPDQ--FQKCVAYVRQDDI 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3926 LLDNLTVREHLLLFASIKAPQWTKKELHQQVNQT--LQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPT 4003
Cdd:cd03234    92 LLPGLTVRETLTYTAILRLPRKSSDAIRKKRVEDvlLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPT 171
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4004 SGVDPCSRHSLWDILLKY-REGRTIIFTTHH-LDEAEALSDRVAVLQHGRLRCCG 4056
Cdd:cd03234   172 SGLDSFTALNLVSTLSQLaRRNRIVILTIHQpRSDLFRLFDRILLLSSGEIVYSG 226
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
3853-4056 2.85e-33

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 128.71  E-value: 2.85e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQtdlsrvrmelgvcpqqdilldnltv 3932
Cdd:cd03214    10 GGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLA------------------------- 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3933 rehlllfasikapQWTKKELHQQ---VNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPC 4009
Cdd:cd03214    65 -------------SLSPKELARKiayVPQALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDIA 131
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 767944871 4010 SRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCG 4056
Cdd:cd03214   132 HQIELLELLrrLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
3838-4067 3.27e-33

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 139.13  E-value: 3.27e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3838 SAPGVTLVSVTKEYEGH-KAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT-DLSRVRM 3915
Cdd:COG4987   330 GGPSLELEDVSFRYPGAgRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDlDEDDLRR 409
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3916 ELGVCPQQDILLDNlTVREHLLLFAsikaPQWTKKELHQqvnqTLQDVDLTQHQHKQT-----------RALSGGLKRKL 3984
Cdd:COG4987   410 RIAVVPQRPHLFDT-TLRENLRLAR----PDATDEELWA----ALERVGLGDWLAALPdgldtwlgeggRRLSGGERRRL 480
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3985 SLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEALsDRVAVLQHGRLRCCGPPFCLKEA 4064
Cdd:COG4987   481 ALARALLRDAPILLLDEPTEGLDAATEQALLADLLEALAGRTVLLITHRLAGLERM-DRILVLEDGRIVEQGTHEELLAQ 559

                  ...
gi 767944871 4065 YGQ 4067
Cdd:COG4987   560 NGR 562
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
3842-4052 7.26e-33

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 129.62  E-value: 7.26e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHK---AVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT----DLSRVR 3914
Cdd:cd03258     2 IELKNVSKVFGDTGgkvTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLlsgkELRKAR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3915 MELGVCPQQDILLDNLTVREHLLLfaSIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKlsLGIA-FMGM 3993
Cdd:cd03258    82 RRIGMIFQHFNLLSSRTVFENVAL--PLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQR--VGIArALAN 157
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 3994 SRTVVL-DEPTSGVDPCSRHSLWDILLKYRE--GRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:cd03258   158 NPKVLLcDEATSALDPETTQSILALLRDINRelGLTIVLITHEMEVVKRICDRVAVMEKGEV 219
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
3837-4058 8.37e-33

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 137.58  E-value: 8.37e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3837 GSAPGVTLVSVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT-DLSRVRM 3915
Cdd:COG4988   332 AGPPSIELEDVSFSYPGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDlDPASWRR 411
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3916 ELGVCPQQDILLdNLTVREHLLLFasikAPQWTKKELHQQVNQTLQDVDLTQHQHK-QT------RALSGGLKRKLSLGI 3988
Cdd:COG4988   412 QIAWVPQNPYLF-AGTIRENLRLG----RPDASDEELEAALEAAGLDEFVAALPDGlDTplgeggRGLSGGQAQRLALAR 486
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3989 AFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAeALSDRVAVLQHGRLRCCGPP 4058
Cdd:COG4988   487 ALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAKGRTVILITHRLALL-AQADRILVLDDGRIVEQGTH 555
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
3853-4058 2.19e-32

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 128.18  E-value: 2.19e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLS---RVRMELGVCPQQDILLDN 3929
Cdd:COG0410    14 GGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDI-TGLPphrIARLGIGYVPEGRRIFPS 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3930 LTVREHLLLFASIKAPQwtkkelhQQVNQTLQDV-----DLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTS 4004
Cdd:COG0410    93 LTVEENLLLGAYARRDR-------AEVRADLERVyelfpRLKERRRQRAGTLSGGEQQMLAIGRALMSRPKLLLLDEPSL 165
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 4005 GVDPCSRHSLWDIL--LKyREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:COG0410   166 GLAPLIVEEIFEIIrrLN-REGVTILLVEQNARFALEIADRAYVLERGRIVLEGTA 220
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
3844-4058 8.65e-32

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 126.14  E-value: 8.65e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3844 LVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHP-----PTSGTIIINGKN---LQTDLSRVRM 3915
Cdd:cd03260     3 LRDLNVYY-GDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDlipgaPDEGEVLLDGKDiydLDVDVLELRR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3916 ELGVCPQQDILLDnLTVREHLLLfasikAPQ----WTKKELHQQVNQTLQDVDLTQ--HQHKQTRALSGGLKRKLSLGIA 3989
Cdd:cd03260    82 RVGMVFQKPNPFP-GSIYDNVAY-----GLRlhgiKLKEELDERVEEALRKAALWDevKDRLHALGLSGGQQQRLCLARA 155
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 3990 FMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:cd03260   156 LANEPEVLLLDEPTSALDPISTAKIEELIAELKKEYTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPT 224
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
4688-4915 3.69e-31

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 124.86  E-value: 3.69e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHyrrfFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSG------HAIIRTPmgdAVDLS 4761
Cdd:cd03219     1 LEVRGLTKR----FGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGsvlfdgEDITGLP---PHEIA 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4762 SAG------TAGVLigycPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEV---AGDLIRRLHLEAHADKPVATYSGGTK 4832
Cdd:cd03219    74 RLGigrtfqIPRLF----PELTVLENVMVAAQARTGSGLLLARARREEREArerAEELLERVGLADLADRPAGELSYGQQ 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4833 RKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQH 4912
Cdd:cd03219   150 RRLEIARALATDPKLLLLDEPAAGLNPEETEELAELIRELRERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDE 229

                  ...
gi 767944871 4913 IKN 4915
Cdd:cd03219   230 VRN 232
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
3842-4052 4.49e-31

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 124.01  E-value: 4.49e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT----DLSRVRMEL 3917
Cdd:COG2884     2 IRFENVSKRYPGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRlkrrEIPYLRRRI 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3918 GVCPqQDI-LLDNLTVREHLLLfaSIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKlsLGIAfmgmsRT 3996
Cdd:COG2884    82 GVVF-QDFrLLPDRTVYENVAL--PLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQR--VAIA-----RA 151
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 3997 VV-------LDEPTSGVDPCSRHSLWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:COG2884   152 LVnrpelllADEPTGNLDPETSWEIMELLEEInRRGTTVLIATHDLELVDRMPKRVLELEDGRL 215
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
4686-4917 1.31e-30

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 123.27  E-value: 1.31e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4686 DILVLYNLSKHYRRF------FQNII------------AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGH 4747
Cdd:COG1134     3 SMIEVENVSKSYRLYhepsrsLKELLlrrrrtrreefwALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGR 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4748 AIIRtpmgdavdlssaGTAGVLIGYcpqQDALDELLTGWEHLYYYCSLRGIPRQ----CIPEV---AGdlirrlhLEAHA 4820
Cdd:COG1134    83 VEVN------------GRVSALLEL---GAGFHPELTGRENIYLNGRLLGLSRKeideKFDEIvefAE-------LGDFI 140
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4821 DKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDP-----CSKRylwqtiMKEVRE-GCAAVLTSHSMEECEALCT 4894
Cdd:COG1134   141 DQPVKTYSSGMRARLAFAVATAVDPDILLVDEVLAVGDAafqkkCLAR------IRELREsGRTVIFVSHSMGAVRRLCD 214
                         250       260
                  ....*....|....*....|...
gi 767944871 4895 RLAIMVNGSFKCLGSPQHIKNRF 4917
Cdd:COG1134   215 RAIWLEKGRLVMDGDPEEVIAAY 237
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
4687-4915 1.32e-30

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 123.61  E-value: 1.32e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHyrrfFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSG--------------HAIIRt 4752
Cdd:COG0411     4 LLEVRGLTKR----FGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGrilfdgrditglppHRIAR- 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4753 pmgdavdlssagtAGV-----LIGYCPQQDALDELLTG---WEHLYYYCSLRGIPRQC-----IPEVAGDLIRRLHLEAH 4819
Cdd:COG0411    79 -------------LGIartfqNPRLFPELTVLENVLVAahaRLGRGLLAALLRLPRARreereARERAEELLERVGLADR 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4820 ADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTImKEVRE--GCAAVLTSHSMEECEALCTRLA 4897
Cdd:COG0411   146 ADEPAGNLSYGQQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELI-RRLRDerGITILLIEHDMDLVMGLADRIV 224
                         250
                  ....*....|....*...
gi 767944871 4898 IMVNGSFKCLGSPQHIKN 4915
Cdd:COG0411   225 VLDFGRVIAEGTPAEVRA 242
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
4692-4902 1.39e-30

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 120.04  E-value: 1.39e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYrrffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTAGVLIG 4771
Cdd:cd00267     4 NLSFRY----GGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILID---GKDIAKLPLEELRRRIG 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4772 YCPQqdaldelltgwehlyyycslrgiprqcipevagdlirrlhleahadkpvatYSGGTKRKLSTALALVGKPDILLLD 4851
Cdd:cd00267    77 YVPQ---------------------------------------------------LSGGQRQRVALARALLLNPDLLLLD 105
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4852 EPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:cd00267   106 EPTSGLDPASRERLLELLRELAEEGRTVIIVTHDPELAELAADRVIVLKDG 156
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
3847-4064 1.83e-30

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 122.68  E-value: 1.83e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT----DLSRVRMELGVCPQ 3922
Cdd:cd03256     6 LSKTYPNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKlkgkALRQLRRQIGMIFQ 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3923 QDILLDNLTVREHLL--------LFASIkaPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMS 3994
Cdd:cd03256    86 QFNLIERLSVLENVLsgrlgrrsTWRSL--FGLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARALMQQP 163
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 3995 RTVVLDEPTSGVDPCSRHSLWDILLKY--REGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPFCLKEA 4064
Cdd:cd03256   164 KLILADEPVASLDPASSRQVMDLLKRInrEEGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAELTDE 235
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
3842-4052 2.26e-30

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 119.84  E-value: 2.26e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVcp 3921
Cdd:cd03216     1 LELRGITKRFGGVKAL-DGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASPRDARRAGI-- 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 qqdilldnLTVrehlllfasikapqwtkkelHQqvnqtlqdvdltqhqhkqtraLSGGLKRKLSLGIAFMGMSRTVVLDE 4001
Cdd:cd03216    78 --------AMV--------------------YQ---------------------LSVGERQMVEIARALARNARLLILDE 108
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 767944871 4002 PTSGVDPCSRHSLWDIL--LKyREGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:cd03216   109 PTAALTPAEVERLFKVIrrLR-AQGVAVIFISHRLDEVFEIADRVTVLRDGRV 160
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
3837-4052 2.40e-30

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 128.99  E-value: 2.40e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3837 GSAPGVTLVSVTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRME 3916
Cdd:COG3845     1 MMPPALELRGITKRFGGVVAN-DDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRSPRDAIA 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3917 LGV--CPQQDILLDNLTVREHLLL-FASIKAPQWTKKELHQQVNQTLQ----DVDLTQHQHKqtraLSGGLKRK------ 3983
Cdd:COG3845    80 LGIgmVHQHFMLVPNLTVAENIVLgLEPTKGGRLDRKAARARIRELSEryglDVDPDAKVED----LSVGEQQRveilka 155
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3984 LSLGiafmgmSRTVVLDEPTSGVDPCSRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:COG3845   156 LYRG------ARILILDEPTAVLTPQEADELFEILRRLAaEGKSIIFITHKLREVMAIADRVTVLRRGKV 219
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
3847-4058 4.09e-30

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 121.67  E-value: 4.09e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLS---RVRMELGVCPQQ 3923
Cdd:COG1137     9 LVKSY-GKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDI-THLPmhkRARLGIGYLPQE 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3924 DILLDNLTVREHLLLFASIKAPqwTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPT 4003
Cdd:COG1137    87 ASIFRKLTVEDNILAVLELRKL--SKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKFILLDEPF 164
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 4004 SGVDPCSRHSLWDILLKYRE-GRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:COG1137   165 AGVDPIAVADIQKIIRHLKErGIGVLITDHNVRETLGICDRAYIISEGKVLAEGTP 220
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
3845-4052 6.42e-30

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 120.69  E-value: 6.42e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3845 VSVT-KEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLSRVRM-----ELG 3918
Cdd:cd03257     7 LSVSfPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDL-LKLSRRLRkirrkEIQ 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3919 VCPQQDIL-LD-NLTVREHL---LLFASIKAPQWTKKElhqQVNQTLQDVDL-TQHQHKQTRALSGGLKRKLSLGIAFMG 3992
Cdd:cd03257    86 MVFQDPMSsLNpRMTIGEQIaepLRIHGKLSKKEARKE---AVLLLLVGVGLpEEVLNRYPHELSGGQRQRVAIARALAL 162
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 3993 MSRTVVLDEPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:cd03257   163 NPKLLIADEPTSALDVSVQAQILDLLkkLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKI 224
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
3853-4058 9.30e-30

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 121.60  E-value: 9.30e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT----DLSRVRME-LGVCPQQDILL 3927
Cdd:cd03294    35 GQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAmsrkELRELRRKkISMVFQSFALL 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3928 DNLTVREHLLLFASIKAPqwTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVD 4007
Cdd:cd03294   115 PHRTVLENVAFGLEVQGV--PRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALD 192
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 767944871 4008 PCSRHSLWDILLKY--REGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:cd03294   193 PLIRREMQDELLRLqaELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTP 245
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
4707-4855 1.19e-29

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 117.36  E-value: 1.19e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4707 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTAGVLIGYCPQQDALDELLTGW 4786
Cdd:pfam00005    1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLD---GQDLTDDERKSLRKEIGYVFQDPQLFPRLTVR 77
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871  4787 EHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPV----ATYSGGTKRKLSTALALVGKPDILLLDEPSS 4855
Cdd:pfam00005   78 ENLRLGLLLKGLSKREKDARAEEALEKLGLGDLADRPVgerpGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
4688-4902 1.32e-29

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 119.94  E-value: 1.32e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYRRFF------------------QNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAI 4749
Cdd:cd03220     1 IELENVSKSYPTYKggssslkklgilgrkgevGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4750 IRtpmGDAVDLSSAGTagvligycpqqdALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSG 4829
Cdd:cd03220    81 VR---GRVSSLLGLGG------------GFNPELTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSS 145
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 4830 GTKRKLSTALALVGKPDILLLDEPSSGMDP-----CSKRylwqtiMKEVREGCAAV-LTSHSMEECEALCTRLAIMVNG 4902
Cdd:cd03220   146 GMKARLAFAIATALEPDILLIDEVLAVGDAafqekCQRR------LRELLKQGKTViLVSHDPSSIKRLCDRALVLEKG 218
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
3853-4077 1.42e-29

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 120.99  E-value: 1.42e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT----DLSRVRmelGVCPQQDILLD 3928
Cdd:COG4559    12 GGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAwspwELARRR---AVLPQHSSLAF 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3929 NLTVREHLLLFASikAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGG------LKRKLS-LGIAFMGMSRTVVLDE 4001
Cdd:COG4559    89 PFTVEEVVALGRA--PHGSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGeqqrvqLARVLAqLWEPVDGGPRWLFLDE 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4002 PTSGVDPCSRHSLWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPF------CLKEAYgqGLRLTLT 4074
Cdd:COG4559   167 PTSALDLAHQHAVLRLARQLaRRGGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPEevltdeLLERVY--GADLRVL 244

                  ...
gi 767944871 4075 RQP 4077
Cdd:COG4559   245 AHP 247
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
3842-4058 2.84e-29

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 119.26  E-value: 2.84e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLSRVRMELGVCP 3921
Cdd:cd03300     1 IELENVSKFY-GGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDI-TNLPPHKRPVNTVF 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QQDILLDNLTVREHLLLFASIKapQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDE 4001
Cdd:cd03300    79 QNYALFPHLTVFENIAFGLRLK--KLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDE 156
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 4002 PTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:cd03300   157 PLGALDLKLRKDMQLELkrLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTP 215
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
3842-4053 3.75e-29

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 118.13  E-value: 3.75e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLSRVRMELGVCP 3921
Cdd:cd03301     1 VELENVTKRFGNVTAL-DDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDV-TDLPPKDRDIAMVF 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QQDILLDNLTVREHLLLfaSIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDE 4001
Cdd:cd03301    79 QNYALYPHMTVYDNIAF--GLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDE 156
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 767944871 4002 PTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLR 4053
Cdd:cd03301   157 PLSNLDAKLRVQMRAELkrLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQ 210
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
4688-4915 4.41e-29

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 118.41  E-value: 4.41e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYRrffqNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSA---G 4764
Cdd:cd03218     1 LRAENLSKRYG----KRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILL-----DGQDITKLpmhK 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4765 TAGVLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGK 4844
Cdd:cd03218    72 RARLGIGYLPQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATN 151
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4845 PDILLLDEPSSGMDPCSKRYLwQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKN 4915
Cdd:cd03218   152 PKFLLLDEPFAGVDPIAVQDI-QKIIKILKDrGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIAA 222
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
3838-4057 6.57e-29

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 124.75  E-value: 6.57e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3838 SAPGVTLVSVTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMEL 3917
Cdd:COG1129     1 AEPLLEMRGISKSFGGVKAL-DGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPRDAQAA 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3918 GV-CPQQDI-LLDNLTVREHLLLFASIKAPQWT-KKELHQQVNQTLQDVDLTQHQHKQTRALSGGLK------RKLSLGi 3988
Cdd:COG1129    80 GIaIIHQELnLVPNLSVAENIFLGREPRRGGLIdWRAMRRRARELLARLGLDIDPDTPVGDLSVAQQqlveiaRALSRD- 158
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 3989 afmgmSRTVVLDEPTSGVDPCSRHSLWDIL--LKyREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGP 4057
Cdd:COG1129   159 -----ARVLILDEPTASLTEREVERLFRIIrrLK-AQGVAIIYISHRLDEVFEIADRVTVLRDGRLVGTGP 223
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
3853-4058 6.60e-29

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 125.02  E-value: 6.60e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPT---SGTIIINGKNLQTDLSRVR-MELGVCPQQ-DILL 3927
Cdd:COG1123    17 GDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLELSEALRgRRIGMVFQDpMTQL 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3928 DNLTVREHLLLfaSIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVD 4007
Cdd:COG1123    97 NPVTVGDQIAE--ALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDLLIADEPTTALD 174
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 767944871 4008 PCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:COG1123   175 VTTQAEILDLLreLQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPP 227
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
4687-4913 7.31e-29

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 118.61  E-value: 7.31e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYRRFfqniIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTA 4766
Cdd:COG1120     1 MLEAENLSVGYGGR----PVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLL-----DGRDLASLSRR 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4767 GV--LIGYCPQQDALDELLTGWE--------HLyyycSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLS 4836
Cdd:COG1120    72 ELarRIAYVPQEPPAPFGLTVRElvalgrypHL----GLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVL 147
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4837 TALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:COG1120   148 IARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARErGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEV 225
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
4692-4899 7.72e-29

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 117.57  E-value: 7.72e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGtagvlIG 4771
Cdd:cd03293     5 NVSKTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVD---GEPVTGPGPD-----RG 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4772 YCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLD 4851
Cdd:cd03293    77 YVFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLD 156
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 767944871 4852 EPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIM 4899
Cdd:cd03293   157 EPFSALDALTREQLQEELLDIWREtGKTVLLVTHDIDEAVFLADRVVVL 205
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
3842-4057 8.79e-29

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 118.26  E-value: 8.79e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGhKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSG-TIIINGKNL-QTDLSRVRMELG- 3918
Cdd:COG1119     4 LELRNVTVRRGG-KTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGnDVRLFGERRgGEDVWELRKRIGl 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3919 VCPQ-QDILLDNLTVREHLL--LFASIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSR 3995
Cdd:COG1119    83 VSPAlQLRFPRDETVLDVVLsgFFDSIGLYREPTDEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLIARALVKDPE 162
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 3996 TVVLDEPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGP 4057
Cdd:COG1119   163 LLILDEPTAGLDLGARELLLALLdkLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGRVVAAGP 226
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
4690-4908 1.26e-28

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 116.48  E-value: 1.26e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4690 LYNLSKHYRRFfqniIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTpmgdavdlSSAGTAGVL 4769
Cdd:cd03235     2 VEDLTVSYGGH----PVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFG--------KPLEKERKR 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4770 IGYCPQQ---------DALDELLTGwehLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALA 4840
Cdd:cd03235    70 IGYVPQRrsidrdfpiSVRDVVLMG---LYGHKGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARA 146
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4841 LVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRlAIMVNGSFKCLG 4908
Cdd:cd03235   147 LVQDPDLLLLDEPFAGVDPKTQEDIYELLRELRREGMTILVVTHDLGLVLEYFDR-VLLLNRTVVASG 213
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
3838-4052 2.48e-28

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 114.96  E-value: 2.48e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3838 SAPGVTLVSVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPP--TSGTIIINGKNLqtDLSRVRM 3915
Cdd:cd03213     5 SFRNLTVTVKSSPSKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGlgVSGEVLINGRPL--DKRSFRK 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3916 ELGVCPQQDILLDNLTVREHLLLFASIkapqwtkkelhqqvnqtlqdvdltqhqhkqtRALSGGLKRKLSLGIAFMGMSR 3995
Cdd:cd03213    83 IIGYVPQDDILHPTLTVRETLMFAAKL-------------------------------RGLSGGERKRVSIALELVSNPS 131
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 3996 TVVLDEPTSGVDPCSRHSLWDILLKYR-EGRTIIFTTHHL-DEAEALSDRVAVLQHGRL 4052
Cdd:cd03213   132 LLFLDEPTSGLDSSSALQVMSLLRRLAdTGRTIICSIHQPsSEIFELFDKLLLLSQGRV 190
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
4692-4925 3.45e-28

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 118.65  E-value: 3.45e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRF-----------------FQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGevsltsghaiIRTPm 4754
Cdd:COG4586     6 NLSKTYRVYekepglkgalkglfrreYREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTG----------ILVP- 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4755 gdavdlsSAGTAGVLiGYCPQQD-----------------------ALD--ELLtgwEHLYyycslrGIPRQCIPEVAGD 4809
Cdd:COG4586    75 -------TSGEVRVL-GYVPFKRrkefarrigvvfgqrsqlwwdlpAIDsfRLL---KAIY------RIPDAEYKKRLDE 137
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4810 LIRRLHLEAHADKPVatysggtkRKLS--------TALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAV 4880
Cdd:COG4586   138 LVELLDLGELLDTPV--------RQLSlgqrmrceLAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRErGTTIL 209
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 767944871 4881 LTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKNRFGDGYTVKV 4925
Cdd:COG4586   210 LTSHDMDDIEALCDRVIVIDHGRIIYDGSLEELKERFGPYKTIVL 254
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
3857-4052 3.58e-28

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 115.90  E-value: 3.58e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3857 VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLSRVRMELGVCPQQDILLDNLTVREHL 3936
Cdd:cd03299    14 KLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDI-TNLPPEKRDISYVPQNYALFPHMTVYKNI 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3937 LLfaSIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWD 4016
Cdd:cd03299    93 AY--GLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKEKLRE 170
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 767944871 4017 ILLKYRE--GRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:cd03299   171 ELKKIRKefGVTVLHVTHDFEEAWALADKVAIMLNGKL 208
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
3847-4050 5.99e-28

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 114.28  E-value: 5.99e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDlSRVRMeLGVCPQ--QD 3924
Cdd:cd03226     5 ISFSYKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAK-ERRKS-IGYVMQdvDY 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3925 ILLDNlTVREHLLLfasikapqwTKKELH---QQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDE 4001
Cdd:cd03226    83 QLFTD-SVREELLL---------GLKELDagnEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDE 152
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 767944871 4002 PTSGVDPCSRHSLWDILLK-YREGRTIIFTTHHLDEAEALSDRVAVLQHG 4050
Cdd:cd03226   153 PTSGLDYKNMERVGELIRElAAQGKAVIVITHDYEFLAKVCDRVLLLANG 202
LPS_export_lptB TIGR04406
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ...
3849-4058 6.20e-28

LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 275199 [Multi-domain]  Cd Length: 239  Bit Score: 115.45  E-value: 6.20e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3849 KEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDL---SRVRMELGVCPQQDI 3925
Cdd:TIGR04406    9 KSY-KKRKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDI-THLpmhERARLGIGYLPQEAS 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3926 LLDNLTVREHLLLFASIKaPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSG 4005
Cdd:TIGR04406   87 IFRKLTVEENIMAVLEIR-KDLDRAEREERLEALLEEFQISHLRDNKAMSLSGGERRRVEIARALATNPKFILLDEPFAG 165
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 767944871  4006 VDPCSRHSLWDILLKYRE-GRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:TIGR04406  166 VDPIAVGDIKKIIKHLKErGIGVLITDHNVRETLDICDRAYIISDGKVLAEGTP 219
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
4695-4902 7.19e-28

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 114.14  E-value: 7.19e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4695 KHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAII----RTPMgDAVDLSSagtagvLI 4770
Cdd:COG4619     4 EGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLdgkpLSAM-PPPEWRR------QV 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4771 GYCPQQDALdelltgW-----EHLYYYCSLRGIPRQciPEVAGDLIRRLHLEAHA-DKPVATYSGGTKRKLSTALALVGK 4844
Cdd:COG4619    77 AYVPQEPAL------WggtvrDNLPFPFQLRERKFD--RERALELLERLGLPPDIlDKPVERLSGGERQRLALIRALLLQ 148
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 4845 PDILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:COG4619   149 PDVLLLDEPTSALDPENTRRVEELLREYLAEeGRAVLWVSHDPEQIERVADRVLTLEAG 207
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
3842-4052 1.03e-27

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 117.87  E-value: 1.03e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHKA---VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT----DLSRVR 3914
Cdd:COG1135     2 IELENLSKTFPTKGGpvtALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTAlserELRAAR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3915 MELGVCPQQDILLDNLTVREhlllfaSIKAP----QWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKlsLGIAf 3990
Cdd:COG1135    82 RKIGMIFQHFNLLSSRTVAE------NVALPleiaGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQR--VGIA- 152
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 3991 mgmsR------TVVL-DEPTSGVDPCSRHSLWDILLKYRE--GRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:COG1135   153 ----RalannpKVLLcDEATSALDPETTRSILDLLKDINRelGLTIVLITHEMDVVRRICDRVAVLENGRI 219
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
3853-4058 1.23e-27

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 115.25  E-value: 1.23e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQ----TDLSRVRmelGVCPQQDILLD 3928
Cdd:PRK13548   13 GGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLAdwspAELARRR---AVLPQHSSLSF 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3929 NLTVREHLLLFASIkapqWT--KKELHQQVNQTLQDVDLTQHQHKQTRALSGG------LKRKLSLGIAFMGMSRTVVLD 4000
Cdd:PRK13548   90 PFTVEEVVAMGRAP----HGlsRAEDDALVAAALAQVDLAHLAGRDYPQLSGGeqqrvqLARVLAQLWEPDGPPRWLLLD 165
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4001 EPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK13548  166 EPTSALDLAHQHHVLRLArqLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTP 225
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
4688-4902 1.37e-27

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 113.74  E-value: 1.37e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAG 4767
Cdd:cd03255     1 IELKNLSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRV-----DGTDISKLSEKE 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4768 VL------IGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALAL 4841
Cdd:cd03255    76 LAafrrrhIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARAL 155
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4842 VGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEEcEALCTRLAIMVNG 4902
Cdd:cd03255   156 ANDPKIILADEPTGNLDSETGKEVMELLRELNKEaGTTIVVVTHDPEL-AEYADRIIELRDG 216
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
3829-4052 1.63e-27

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 114.35  E-value: 1.63e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3829 QNREGELEGSAPGVtlvsVTKEYEgHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIING----K 3904
Cdd:cd03267    13 YSKEPGLIGSLKSL----FKRKYR-EVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGlvpwK 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3905 NLQTDLSRVRMELGvcpQQDILLDNLTVREHLLLFASIKapQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKL 3984
Cdd:cd03267    88 RRKKFLRRIGVVFG---QKTQLWWDLPVIDSFYLLAAIY--DLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRA 162
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3985 SLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGR--TIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:cd03267   163 EIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERgtTVLLTSHYMKDIEALARRVLVIDKGRL 232
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
4687-4913 1.87e-27

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 113.97  E-value: 1.87e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYRRffqnIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSS---- 4762
Cdd:COG1137     3 TLEAENLVKSYGK----RTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFL-----DGEDITHlpmh 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4763 ----AGtagvlIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTA 4838
Cdd:COG1137    74 krarLG-----IGYLPQEASIFRKLTVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIA 148
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 4839 LALVGKPDILLLDEPSSGMDPCSKRYLwQTIMKEVREGCAAVL-TSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:COG1137   149 RALATNPKFILLDEPFAGVDPIAVADI-QKIIRHLKERGIGVLiTDHNVRETLGICDRAYIISEGKVLAEGTPEEI 223
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
4687-4913 2.62e-27

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 120.01  E-value: 2.62e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYRRffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGevsLTSGHAIIR---TPMGDAVDLSSA 4763
Cdd:COG1123     4 LLEVRDLSVRYPG--GDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMG---LLPHGGRISgevLLDGRDLLELSE 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4764 GTAGVLIGYCPQqDALDEL--LTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALAL 4841
Cdd:COG1123    79 ALRGRRIGMVFQ-DPMTQLnpVTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMAL 157
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871 4842 VGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:COG1123   158 ALDPDLLIADEPTTALDVTTQAEILDLLRELQRErGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEI 230
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
3833-4052 4.67e-27

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 121.09  E-value: 4.67e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3833 GELEGSapgVTLVSVTKEYEGH-KAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT-DL 3910
Cdd:COG2274   468 PRLKGD---IELENVSFRYPGDsPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQiDP 544
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3911 SRVRMELGVCPQQDILLdNLTVREHLLLFASiKAPQwtkkelhQQVNQTLQDVDLT----QHQHK-QT------RALSGG 3979
Cdd:COG2274   545 ASLRRQIGVVLQDVFLF-SGTIRENITLGDP-DATD-------EEIIEAARLAGLHdfieALPMGyDTvvgeggSNLSGG 615
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871 3980 LKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLdEAEALSDRVAVLQHGRL 4052
Cdd:COG2274   616 QRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLKGRTVIIIAHRL-STIRLADRIIVLDKGRI 687
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
3845-4052 1.17e-26

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 112.20  E-value: 1.17e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3845 VSVT-KEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSR-----VRMelg 3918
Cdd:COG1124     7 LSVSyGQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKafrrrVQM--- 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3919 VcpQQDIL--LD-NLTVREHLLLFASIKapqwTKKELHQQVNQTLQDVDLTQ-------HQhkqtraLSGGLKRKLSLGI 3988
Cdd:COG1124    84 V--FQDPYasLHpRHTVDRILAEPLRIH----GLPDREERIAELLEQVGLPPsfldrypHQ------LSGGQRQRVAIAR 151
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 3989 AFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYRE--GRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:COG1124   152 ALILEPELLLLDEPTSALDVSVQAEILNLLKDLREerGLTYLFVSHDLAVVAHLCDRVAVMQNGRI 217
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
3869-4053 1.71e-26

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 110.46  E-value: 1.71e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3869 QITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGK-----NLQTDLSRVRMELGVCPQQDILLDNLTVREHLLLFASIK 3943
Cdd:cd03297    24 EVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTvlfdsRKKINLPPQQRKIGLVFQQYALFPHLNVRENLAFGLKRK 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3944 APqwtkKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRhslwDILLKYRE 4023
Cdd:cd03297   104 RN----REDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALR----LQLLPELK 175
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 767944871 4024 GR------TIIFTTHHLDEAEALSDRVAVLQHGRLR 4053
Cdd:cd03297   176 QIkknlniPVIFVTHDLSEAEYLADRIVVMEDGRLQ 211
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
3842-4053 3.29e-26

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 116.70  E-value: 3.29e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHKaVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIInGKNLQtdlsrvrmeLGVCP 3921
Cdd:COG0488   316 LELEGLSKSYGDKT-LLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETVK---------IGYFD 384
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 Q-QDILLDNLTVREHLLLFasikAPQWTKKELHqqvnQTLQDVDLT-QHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVL 3999
Cdd:COG0488   385 QhQEELDPDKTVLDELRDG----APGGTEQEVR----GYLGRFLFSgDDAFKPVGVLSGGEKARLALAKLLLSPPNVLLL 456
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 4000 DEPTSGVDPCSRHSLWDILLKYrEGrTIIFTTHhlDEA--EALSDRVAVLQHGRLR 4053
Cdd:COG0488   457 DEPTNHLDIETLEALEEALDDF-PG-TVLLVSH--DRYflDRVATRILEFEDGGVR 508
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
4687-4917 3.58e-26

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 113.65  E-value: 3.58e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYRRFFqniiAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSsagta 4766
Cdd:COG3842     5 ALELENVSKRYGDVT----ALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILL-----DGRDVT----- 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4767 GVL-----IGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTK-RklsTALA 4840
Cdd:COG3842    71 GLPpekrnVGMVFQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQqR---VALA 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4841 --LVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI---- 4913
Cdd:COG3842   148 raLAPEPRVLLLDEPLSALDAKLREEMREELRRLQRElGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIyerp 227

                  ....
gi 767944871 4914 KNRF 4917
Cdd:COG3842   228 ATRF 231
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
4687-4902 6.63e-26

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 109.13  E-value: 6.63e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTA 4766
Cdd:cd03257     1 LLEVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIF-----DGKDLLKLSRR 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4767 GVL-----IGYCPQ--QDALDELLTGWEHLY--YYCSLRGIPRQCIPEVAGDLIRRLHL-EAHADKPVATYSGGTKRKLS 4836
Cdd:cd03257    76 LRKirrkeIQMVFQdpMSSLNPRMTIGEQIAepLRIHGKLSKKEARKEAVLLLLVGVGLpEEVLNRYPHELSGGQRQRVA 155
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4837 TALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:cd03257   156 IARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEElGLTLLFITHDLGVVAKIADRVAVMYAG 222
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
3858-4050 7.76e-26

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 109.09  E-value: 7.76e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3858 VQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLSRVRMelgVCPQQDILLDNLTVREHLL 3937
Cdd:TIGR01184    1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQI-TEPGPDRM---VVFQNYSLLPWLTVRENIA 76
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3938 LFASIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDI 4017
Cdd:TIGR01184   77 LAVDRVLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEE 156
                          170       180       190
                   ....*....|....*....|....*....|....*
gi 767944871  4018 LLKYRE--GRTIIFTTHHLDEAEALSDRVAVLQHG 4050
Cdd:TIGR01184  157 LMQIWEehRVTVLMVTHDVDEALLLSDRVVMLTNG 191
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
4683-4899 8.85e-26

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 109.79  E-value: 8.85e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4683 TNGDILVLYNLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSS 4762
Cdd:COG1116     3 AAAPALELRGVSKRFPTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVD---GKPVTGPG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4763 AGtagvlIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALV 4842
Cdd:COG1116    80 PD-----RGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALA 154
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4843 GKPDILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIM 4899
Cdd:COG1116   155 NDPEVLLMDEPFGALDALTRERLQDELLRLWQEtGKTVLFVTHDVDEAVFLADRVVVL 212
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
4687-4899 1.00e-25

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 108.68  E-value: 1.00e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYRRFFQN---IIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPmGDAVDLSSA 4763
Cdd:COG4778     4 LLEVENLSKTFTLHLQGgkrLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHD-GGWVDLAQA 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4764 GTAGVL------IGYC-------PQQDALD---ELLTgwehlyyycsLRGIPRQCIPEVAGDLIRRLHL-EAHADKPVAT 4826
Cdd:COG4778    83 SPREILalrrrtIGYVsqflrviPRVSALDvvaEPLL----------ERGVDREEARARARELLARLNLpERLWDLPPAT 152
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871 4827 YSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIM 4899
Cdd:COG4778   153 FSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAIIGIFHDEEVREAVADRVVDV 225
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
4688-4913 1.32e-25

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 108.93  E-value: 1.32e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYRRFFQniiAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIR---TPMGDAVDLSSAg 4764
Cdd:cd03295     1 IEFENVTKRYGGGKK---AVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDgedIREQDPVELRRK- 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4765 tagvlIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAH--ADKPVATYSGGTKRKLSTALALV 4842
Cdd:cd03295    77 -----IGYVIQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLDPAefADRYPHELSGGQQQRVGVARALA 151
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4843 GKPDILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:cd03295   152 ADPPLLLMDEPFGALDPITRDQLQEEFKRLQQElGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEI 223
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
4687-4913 1.37e-25

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 108.83  E-value: 1.37e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHY--RRffqniiAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLSSAG 4764
Cdd:PRK10895    3 TLTAKNLAKAYkgRR------VVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARA 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4765 TAGvlIGYCPQQDALDELLTGWEHLYYYCSLR-GIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVG 4843
Cdd:PRK10895   77 RRG--IGYLPQEASIFRRLSVYDNLMAVLQIRdDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAA 154
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4844 KPDILLLDEPSSGMDPCSKRYLwQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:PRK10895  155 NPKFILLDEPFAGVDPISVIDI-KRIIEHLRDsGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEI 224
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
4687-4922 2.52e-25

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 113.84  E-value: 2.52e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYR-RFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGT 4765
Cdd:COG1123   260 LLEVRNLSKRYPvRGKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILF-----DGKDLTKLSR 334
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4766 AGVL-----IGYCPQ--QDALDELLTGWEHLYYYCSLRGI-PRQCIPEVAGDLIRRLHL-EAHADKPVATYSGGTKRKLS 4836
Cdd:COG1123   335 RSLRelrrrVQMVFQdpYSSLNPRMTVGDIIAEPLRLHGLlSRAERRERVAELLERVGLpPDLADRYPHELSGGQRQRVA 414
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4837 TALALVGKPDILLLDEPSSGMDPCSKRylwqTIMKEVRE-----GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQ 4911
Cdd:COG1123   415 IARALALEPKLLILDEPTSALDVSVQA----QILNLLRDlqrelGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTE 490
                         250
                  ....*....|.
gi 767944871 4912 HIKNRFGDGYT 4922
Cdd:COG1123   491 EVFANPQHPYT 501
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
3842-4052 2.63e-25

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 106.85  E-value: 2.63e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL---QTDLSRVRMELG 3918
Cdd:cd03262     1 IEIKNLHKSF-GDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLtddKKNINELRQKVG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3919 VCPQQDILLDNLTVREHLLLfASIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVV 3998
Cdd:cd03262    80 MVFQQFNLFPHLTVLENITL-APIKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVML 158
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 3999 LDEPTSGVDPCSRHSLWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:cd03262   159 FDEPTSALDPELVGEVLDVMKDLaEEGMTMVVVTHEMGFAREVADRVIFMDDGRI 213
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
4692-4902 3.22e-25

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 107.42  E-value: 3.22e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRF-----------------FQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAII--RT 4752
Cdd:cd03267     5 NLSKSYRVYskepgligslkslfkrkYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVagLV 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4753 PMGDAVDLSSagTAGVLIGycpQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTK 4832
Cdd:cd03267    85 PWKRRKKFLR--RIGVVFG---QKTQLWWDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQR 159
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4833 RKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:cd03267   160 MRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRErGTTVLLTSHYMKDIEALARRVLVIDKG 230
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
4690-4902 4.01e-25

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 107.28  E-value: 4.01e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4690 LYNLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGVL 4769
Cdd:cd03258     4 LKNVSKVFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLV-----DGTDLTLLSGKELR 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4770 -----IGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGK 4844
Cdd:cd03258    79 karrrIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANN 158
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 4845 PDILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:cd03258   159 PKVLLCDEATSALDPETTQSILALLRDINRElGLTIVLITHEMEVVKRICDRVAVMEKG 217
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
3821-4047 4.05e-25

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 113.54  E-value: 4.05e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3821 FDNKGSSLQNREGELEGSAPGVTLVSVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTII 3900
Cdd:TIGR02857  301 LDAAPRPLAGKAPVTAAPASSLEFSGVSVAYPGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIA 380
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3901 INGKNLQT-DLSRVRMELGVCPQQDILLDNlTVREHLLLfasiKAPQWTKKELHQQVNQT-LQDVDLTQHQHKQTRA--- 3975
Cdd:TIGR02857  381 VNGVPLADaDADSWRDQIAWVPQHPFLFAG-TIAENIRL----ARPDASDAEIREALERAgLDEFVAALPQGLDTPIgeg 455
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767944871  3976 ---LSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEALsDRVAVL 4047
Cdd:TIGR02857  456 gagLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQGRTVLLVTHRLALAALA-DRIVVL 529
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
4692-4908 4.09e-25

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 105.21  E-value: 4.09e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRrffQNIIaVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGV--L 4769
Cdd:cd03214     4 NLSVGYG---GRTV-LDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILL-----DGKDLASLSPKELarK 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4770 IGYCPQqdALDelLTGWEHLyyycslrgiprqcipevagdlirrlhleahADKPVATYSGGTKRKLSTALALVGKPDILL 4849
Cdd:cd03214    75 IAYVPQ--ALE--LLGLAHL------------------------------ADRPFNELSGGERQRVLLARALAQEPPILL 120
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4850 LDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLG 4908
Cdd:cd03214   121 LDEPTSHLDIAHQIELLELLRRLARErGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
3847-4052 4.92e-25

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 109.41  E-value: 4.92e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELG-VCPQQDI 3925
Cdd:COG4586    28 FRREYREVEAV-DDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLGYVPFKRRKEFARRIGvVFGQRSQ 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3926 LLDNLTVREHLLLFASI-KAPqwtKKELHQQVNQtLQDV-DLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPT 4003
Cdd:COG4586   107 LWWDLPAIDSFRLLKAIyRIP---DAEYKKRLDE-LVELlDLGELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPT 182
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4004 SGVDPCSRHSLWDILLKY--REGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:COG4586   183 IGLDVVSKEAIREFLKEYnrERGTTILLTSHDMDDIEALCDRVIVIDHGRI 233
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
3855-4052 6.51e-25

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 104.82  E-value: 6.51e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3855 KAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVC-----PQQDILLDN 3929
Cdd:cd03215    13 KGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDAIRAGIAyvpedRKREGLVLD 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3930 LTVREHLLLfasikapqwtkkelhqqvnqtlqdvdltqhqhkqTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPC 4009
Cdd:cd03215    93 LSVAENIAL----------------------------------SSLLSGGNQQKVVLARWLARDPRVLILDEPTRGVDVG 138
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 767944871 4010 SRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:cd03215   139 AKAEIYRLIRELAdAGKAVLLISSELDELLGLCDRILVMYEGRI 182
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
3847-4052 9.48e-25

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 105.57  E-value: 9.48e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLSR-----VRMELGVCP 3921
Cdd:cd03292     6 VTKTYPNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDV-SDLRGraipyLRRKIGVVF 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QQDILLDNLTVREHLLLfaSIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDE 4001
Cdd:cd03292    85 QDFRLLPDRNVYENVAF--ALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADE 162
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4002 PTSGVDPCSRHSLWDILLKYRE-GRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:cd03292   163 PTGNLDPDTTWEIMNLLKKINKaGTTVVVATHAKELVDTTRHRVIALERGKL 214
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
3858-4066 1.83e-24

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 113.68  E-value: 1.83e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3858 VQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTI-----IINGKNLQTdlsrvRMELGVCPQQDILLDNLTV 3932
Cdd:NF033858  282 VDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAwlfgqPVDAGDIAT-----RRRVGYMSQAFSLYGELTV 356
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3933 REHLLLFAsiKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRH 4012
Cdd:NF033858  357 RQNLELHA--RLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARD 434
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4013 SLWDIL--LKYREGRTIIFTTHHLDEAEaLSDRVAvLQH-GRLRCCGPPFCLKEAYG 4066
Cdd:NF033858  435 MFWRLLieLSREDGVTIFISTHFMNEAE-RCDRIS-LMHaGRVLASDTPAALVAARG 489
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
3841-4058 2.06e-24

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 105.11  E-value: 2.06e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3841 GVTLVSVTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLSRVRMELGVC 3920
Cdd:cd03296     2 SIEVRNVSKRFGDFVAL-DDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDA-TDVPVQERNVGFV 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3921 PQQDILLDNLTVREHLLLFASIK--APQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVV 3998
Cdd:cd03296    80 FQHYALFRHMTVFDNVAFGLRVKprSERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLL 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 3999 LDEPTSGVDPCSRHSL--WDILLKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:cd03296   160 LDEPFGALDAKVRKELrrWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTP 221
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
3845-4052 2.42e-24

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 104.11  E-value: 2.42e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3845 VSVTKEYEGHKAVvqDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLSRVRMELGVCPQQD 3924
Cdd:cd03298     3 LDKIRFSYGEQPM--HFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDV-TAAPPADRPVSMLFQEN 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3925 ILLDNLTVREHLLLFASikaPQWTKKELHQQ-VNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPT 4003
Cdd:cd03298    80 NLFAHLTVEQNVGLGLS---PGLKLTAEDRQaIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPF 156
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4004 SGVDPCSRHSLWDILLKYREGR--TIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:cd03298   157 AALDPALRAEMLDLVLDLHAETkmTVLMVTHQPEDAKRLAQRVVFLDNGRI 207
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
4692-4922 3.19e-24

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 104.89  E-value: 3.19e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIR-TPMGDAVDLSSAGTAGVLi 4770
Cdd:COG1124     6 NLSVSYGQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDgRPVTRRRRKAFRRRVQMV- 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4771 gycpQQD---ALDELLTGWEHLYYYCSLRGIPRqcIPEVAGDLIRRLHL-EAHADKPVATYSGGTKRKLSTALALVGKPD 4846
Cdd:COG1124    85 ----FQDpyaSLHPRHTVDRILAEPLRIHGLPD--REERIAELLEQVGLpPSFLDRYPHQLSGGQRQRVAIARALILEPE 158
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4847 ILLLDEPSSGMDPCSKRYLWQTImKEVRE--GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKNRFGDGYT 4922
Cdd:COG1124   159 LLLLDEPTSALDVSVQAEILNLL-KDLREerGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLAGPKHPYT 235
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
3846-4071 3.53e-24

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 104.59  E-value: 3.53e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3846 SVTKEYEGHKaVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINgknlQTDLS------RVRMELGV 3919
Cdd:PRK10895    8 NLAKAYKGRR-VVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIID----DEDISllplhaRARRGIGY 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3920 CPQQDILLDNLTVREHLLLFASIKApQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVL 3999
Cdd:PRK10895   83 LPQEASIFRRLSVYDNLMAVLQIRD-DLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILL 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4000 DEPTSGVDPCSRHSLWDILLKYRE-GRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPFCL------KEAY-GQGLRL 4071
Cdd:PRK10895  162 DEPFAGVDPISVIDIKRIIEHLRDsGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEIlqdehvKRVYlGEDFRL 241
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
4688-4917 5.54e-24

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 103.86  E-value: 5.54e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYRRFfqniIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAG 4767
Cdd:cd03300     1 IELENVSKFYGGF----VALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILL-----DGKDITNLPPHK 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4768 VLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDI 4847
Cdd:cd03300    72 RPVNTVFQNYALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKV 151
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 4848 LLLDEPSSGMDpcskRYLWQTIMKEVRE-----GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI----KNRF 4917
Cdd:cd03300   152 LLLDEPLGALD----LKLRKDMQLELKRlqkelGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIyeepANRF 226
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
3853-4058 5.65e-24

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 104.33  E-value: 5.65e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT----DLSRvrmELGVCPQQDILLD 3928
Cdd:PRK11231   13 GTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMlssrQLAR---RLALLPQHHLTPE 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3929 NLTVREhllLFASIKAPQ---WTK--KELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKlslgiAFMGM-----SRTVV 3998
Cdd:PRK11231   90 GITVRE---LVAYGRSPWlslWGRlsAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQR-----AFLAMvlaqdTPVVL 161
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 3999 LDEPTSGVDPCSRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK11231  162 LDEPTTYLDINHQVELMRLMRELNtQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTP 222
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
3840-4058 6.87e-24

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 107.23  E-value: 6.87e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3840 PGVTLVSVTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKnlqtDLSRV---RME 3916
Cdd:PRK11607   18 PLLEIRNLTKSFDGQHAV-DDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGV----DLSHVppyQRP 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3917 LGVCPQQDILLDNLTVREHLLLfaSIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRT 3996
Cdd:PRK11607   93 INMMFQSYALFPHMTVEQNIAF--GLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKL 170
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 3997 VVLDEPTSGVDPCSR----HSLWDILlkYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK11607  171 LLLDEPMGALDKKLRdrmqLEVVDIL--ERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEP 234
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
4688-4902 1.01e-23

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 101.11  E-value: 1.01e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYrrffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLSSaGTAG 4767
Cdd:cd03229     1 LELKNVSKRY----GQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDEL-PPLR 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4768 VLIGYCPQQDALDELLTGWEHLYYycslrgiprqcipevagdlirRLhleahadkpvatySGGTKRKLSTALALVGKPDI 4847
Cdd:cd03229    76 RRIGMVFQDFALFPHLTVLENIAL---------------------GL-------------SGGQQQRVALARALAMDPDV 121
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4848 LLLDEPSSGMDPCSKRYLwQTIMKEVRE--GCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:cd03229   122 LLLDEPTSALDPITRREV-RALLKSLQAqlGITVVLVTHDLDEAARLADRVVVLRDG 177
COG4674 COG4674
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
3847-4057 1.05e-23

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443710 [Multi-domain]  Cd Length: 250  Bit Score: 103.66  E-value: 1.05e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLS---RVRMelGVCP-- 3921
Cdd:COG4674    16 LTVSFDGFKAL-NDLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRPDSGSVLFGGTDL-TGLDeheIARL--GIGRkf 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QQDILLDNLTVREHLLL--------FASIKApqWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGM 3993
Cdd:COG4674    92 QKPTVFEELTVFENLELalkgdrgvFASLFA--RLTAEERDRIEEVLETIGLTDKADRLAGLLSHGQKQWLEIGMLLAQD 169
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 3994 SRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGP 4057
Cdd:COG4674   170 PKLLLLDEPVAGMTDAETERTAELLKSLAGKHSVVVVEHDMEFVRQIARKVTVLHQGSVLAEGS 233
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
3842-4052 1.61e-23

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 105.65  E-value: 1.61e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHKAVV---QDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL----QTDLSRVR 3914
Cdd:PRK11153    2 IELKNISKVFPQGGRTIhalNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLtalsEKELRKAR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3915 MELGVCPQQDILLDNLTVREHLLLfaSIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKlsLGIAFMGMS 3994
Cdd:PRK11153   82 RQIGMIFQHFNLLSSRTVFDNVAL--PLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQR--VAIARALAS 157
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871 3995 RTVVL--DEPTSGVDPCSRHSLWDiLLK--YRE-GRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:PRK11153  158 NPKVLlcDEATSALDPATTRSILE-LLKdiNRElGLTIVLITHEMDVVKRICDRVAVIDAGRL 219
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
4705-4913 1.84e-23

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 103.49  E-value: 1.84e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4705 IAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGVL------IGYCPQQDA 4778
Cdd:cd03294    38 VGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLI-----DGQDIAAMSRKELRelrrkkISMVFQSFA 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4779 LDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMD 4858
Cdd:cd03294   113 LLPHRTVLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALD 192
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 4859 PCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:cd03294   193 PLIRREMQDELLRLQAElQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEI 248
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
3834-4052 3.27e-23

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 107.94  E-value: 3.27e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3834 ELEGSAPGVTLVSVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT-DLSR 3912
Cdd:COG1132   332 PLPPVRGEIEFENVSFSYPGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDlTLES 411
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3913 VRMELGVCPQQDILLdNLTVREHlLLFASIKAPQwtkkelhQQVNQTLQDVDLTQHQHK-----QTR------ALSGGLK 3981
Cdd:COG1132   412 LRRQIGVVPQDTFLF-SGTIREN-IRYGRPDATD-------EEVEEAAKAAQAHEFIEAlpdgyDTVvgergvNLSGGQR 482
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 3982 RKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEAlSDRVAVLQHGRL 4052
Cdd:COG1132   483 QRIAIARALLKDPPILILDEATSALDTETEALIQEALERLMKGRTTIVIAHRLSTIRN-ADRILVLDDGRI 552
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
3840-4056 5.24e-23

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 106.79  E-value: 5.24e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3840 PGVTLVSVTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELG- 3918
Cdd:PRK09700    4 PYISMAGIGKSFGPVHAL-KSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLAAQLGi 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3919 -VCPQQDILLDNLTVREHLLL-------FASIKAPQWtkKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAF 3990
Cdd:PRK09700   83 gIIYQELSVIDELTVLENLYIgrhltkkVCGVNIIDW--REMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTL 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 3991 MGMSRTVVLDEPTSGVDPCSRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCG 4056
Cdd:PRK09700  161 MLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRkEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSG 227
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
3858-4087 5.35e-23

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 102.62  E-value: 5.35e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3858 VQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqtDLSR-----VRMELGVCPQQ-DILLDNLT 3931
Cdd:PRK13636   22 LKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPI--DYSRkglmkLRESVGMVFQDpDNQLFSAS 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3932 VREHLLLFA-SIKAPqwtKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCS 4010
Cdd:PRK13636  100 VYQDVSFGAvNLKLP---EDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMG 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4011 RHSLWDILLKYRE--GRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP---FCLKEAYgQGLRLTLTRQPSVLEAHDL 4085
Cdd:PRK13636  177 VSEIMKLLVEMQKelGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPkevFAEKEML-RKVNLRLPRIGHLMEILKE 255

                  ..
gi 767944871 4086 KD 4087
Cdd:PRK13636  256 KD 257
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
3853-4056 6.79e-23

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 100.30  E-value: 6.79e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGknlqtdlsRVR--MELGVCpqqdiLLDNL 3930
Cdd:cd03220    33 GEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRG--------RVSslLGLGGG-----FNPEL 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3931 TVREHLLLFASIKApqWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCS 4010
Cdd:cd03220   100 TGRENIYLNGRLLG--LSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVLAVGDAAF 177
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 767944871 4011 RHSLWDILLKYRE-GRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCG 4056
Cdd:cd03220   178 QEKCQRRLRELLKqGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
4688-4916 1.05e-22

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 100.10  E-value: 1.05e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYRRFFqniiaVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAG 4767
Cdd:cd03299     1 LKVENLSKDWKEFK-----LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILL-----NGKDITNLPPEK 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4768 VLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDI 4847
Cdd:cd03299    71 RDISYVPQNYALFPHMTVYKNIAYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKI 150
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4848 LLLDEPSSGMDPCSKRYLwQTIMKEVRE--GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKNR 4916
Cdd:cd03299   151 LLLDEPFSALDVRTKEKL-REELKKIRKefGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKK 220
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
3845-4047 1.07e-22

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 101.09  E-value: 1.07e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3845 VSVTkeYEGHKA---VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSrvrmELGVCP 3921
Cdd:COG4525     9 VSVR--YPGGGQpqpALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTGPGA----DRGVVF 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QQDILLDNLTVREHL---LLFASIKapqwtKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVV 3998
Cdd:COG4525    83 QKDALLPWLNVLDNVafgLRLRGVP-----KAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRFLL 157
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767944871 3999 LDEPTSGVDPCSRHSLWDILLKY--REGRTIIFTTHHLDEAEALSDRVAVL 4047
Cdd:COG4525   158 MDEPFGALDALTREQMQELLLDVwqRTGKGVFLITHSVEEALFLATRLVVM 208
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
3847-4052 1.14e-22

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 99.99  E-value: 1.14e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL-QTDLSRVRMELGVCPQQDI 3925
Cdd:cd03254     8 VNFSYDEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIrDISRKSLRSMIGVVLQDTF 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3926 LLdNLTVREHLLLFASIkapqwTKKELHQQVNQTLQDVDLTQHQHK--QTRA------LSGGLKRKLSLGIAFMGMSRTV 3997
Cdd:cd03254    88 LF-SGTIMENIRLGRPN-----ATDEEVIEAAKEAGAHDFIMKLPNgyDTVLgenggnLSQGERQLLAIARAMLRDPKIL 161
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 3998 VLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEAlSDRVAVLQHGRL 4052
Cdd:cd03254   162 ILDEATSNIDTETEKLIQEALEKLMKGRTSIIIAHRLSTIKN-ADKILVLDDGKI 215
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
4698-4918 1.47e-22

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 107.52  E-value: 1.47e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4698 RRF--FqniIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpMGDAVDlssagtAGVL-----I 4770
Cdd:NF033858  274 MRFgdF---TAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWL---FGQPVD------AGDIatrrrV 341
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4771 GYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLL 4850
Cdd:NF033858  342 GYMSQAFSLYGELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLIL 421
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4851 DEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEaLCTRLAIMVNGsfKCL--GSPQHIKNRFG 4918
Cdd:NF033858  422 DEPTSGVDPVARDMFWRLLIELSREdGVTIFISTHFMNEAE-RCDRISLMHAG--RVLasDTPAALVAARG 489
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
3831-4034 1.54e-22

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 105.52  E-value: 1.54e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3831 REGELEGSAPGVTLVSVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT-D 3909
Cdd:TIGR02868  324 AAGAVGLGKPTLELRDLSAGYPGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSlD 403
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3910 LSRVRMELGVCPQQDILLDNlTVREHLLLfasiKAPQWTKKE---------LHQQVNQTLQDVDLTQHQHkqTRALSGGL 3980
Cdd:TIGR02868  404 QDEVRRRVSVCAQDAHLFDT-TVRENLRL----ARPDATDEElwaalervgLADWLRALPDGLDTVLGEG--GARLSGGE 476
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 767944871  3981 KRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHL 4034
Cdd:TIGR02868  477 RQRLALARALLADAPILLLDEPTEHLDAETADELLEDLLAALSGRTVVLITHHL 530
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
3857-4083 2.95e-22

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 100.08  E-value: 2.95e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3857 VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL---QTDLSRVRMELGVC---PQQDILLDNL 3930
Cdd:PRK13638   16 VLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLdysKRGLLALRQQVATVfqdPEQQIFYTDI 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3931 tvrEHLLLFaSIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCS 4010
Cdd:PRK13638   96 ---DSDIAF-SLRNLGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAG 171
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4011 RHSLWDILLK-YREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP---FCLKEAYGQ-GLrltltRQPSVLEAH 4083
Cdd:PRK13638  172 RTQMIAIIRRiVAQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPgevFACTEAMEQaGL-----TQPWLVKLH 244
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
4687-4913 3.64e-22

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 102.22  E-value: 3.64e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHyrrfFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTA 4766
Cdd:PRK11607   19 LLEIRNLTKS----FDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIML-----DGVDLSHVPPY 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4767 GVLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPD 4846
Cdd:PRK11607   90 QRPINMMFQSYALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPK 169
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4847 ILLLDEPSSGMDpcskRYLWQTIMKEV-----REGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:PRK11607  170 LLLLDEPMGALD----KKLRDRMQLEVvdileRVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEI 237
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
4707-4903 4.38e-22

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 99.00  E-value: 4.38e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAI--------------IRTPMGdavdLSSAGtagvLIGY 4772
Cdd:COG1119    19 LDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNDVrlfgerrggedvweLRKRIG----LVSPA----LQLR 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4773 CPQQD-ALDELLTGwehlyYYCSLrGIPRQCIPE---VAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDIL 4848
Cdd:COG1119    91 FPRDEtVLDVVLSG-----FFDSI-GLYREPTDEqreRARELLELLGLAHLADRPFGTLSQGEQRRVLIARALVKDPELL 164
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 4849 LLDEPSSGMDPCSKRYLWQTIMKEVREG-CAAVLTSHSMEECEALCTRLAIMVNGS 4903
Cdd:COG1119   165 ILDEPTAGLDLGARELLLALLDKLAAEGaPTLVLVTHHVEEIPPGITHVLLLKDGR 220
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
4692-4853 4.55e-22

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 103.99  E-value: 4.55e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHY--RRFFQniiavqDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmgdavdlssagtAGVL 4769
Cdd:COG0488     3 NLSKSFggRPLLD------DVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIP--------------KGLR 62
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4770 IGYCPQ-------QDALDELLTGWEHL------YYYCSLRGIPRQCIPEVAGDLIRRLH------LEAHA---------- 4820
Cdd:COG0488    63 IGYLPQeppldddLTVLDTVLDGDAELraleaeLEELEAKLAEPDEDLERLAELQEEFEalggweAEARAeeilsglgfp 142
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 767944871 4821 ----DKPVATYSGGTKRKLSTALALVGKPDILLLDEP 4853
Cdd:COG0488   143 eedlDRPVSELSGGWRRRVALARALLSEPDLLLLDEP 179
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
3852-4052 5.53e-22

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 96.23  E-value: 5.53e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3852 EGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCPQQDILLDNlT 3931
Cdd:cd03247    12 EQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKALSSLISVLNQRPYLFDT-T 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3932 VREHLllfasikapqwtkkelhqqvnqtlqdvdltqhqhkqTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSR 4011
Cdd:cd03247    91 LRNNL------------------------------------GRRFSGGERQRLALARILLQDAPIVLLDEPTVGLDPITE 134
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 767944871 4012 HSLWDILLKYREGRTIIFTTHHLDEAEALsDRVAVLQHGRL 4052
Cdd:cd03247   135 RQLLSLIFEVLKDKTLIWITHHLTGIEHM-DKILFLENGKI 174
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
4706-4888 5.91e-22

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 96.53  E-value: 5.91e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGevsltsghaiIRTPMGDAVdlssAGTAGVLIGYCPQQDALDELL-- 4783
Cdd:NF040873    7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAG----------VLRPTSGTV----RRAGGARVAYVPQRSEVPDSLpl 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4784 -------TG-WEHLYYYCSLRGIPRQcipeVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSS 4855
Cdd:NF040873   73 tvrdlvaMGrWARRGLWRRLTRDDRA----AVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTT 148
                         170       180       190
                  ....*....|....*....|....*....|...
gi 767944871 4856 GMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEE 4888
Cdd:NF040873  149 GLDAESRERIIALLAEEHARGATVVVVTHDLEL 181
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
4705-4921 8.29e-22

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 101.65  E-value: 8.29e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4705 IAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGVL------IGYCPQQDA 4778
Cdd:PRK10070   42 LGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLI-----DGVDIAKISDAELRevrrkkIAMVFQSFA 116
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4779 LDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMD 4858
Cdd:PRK10070  117 LMPHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALD 196
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 4859 PCSKRYLWQTIMK-EVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKNRFGDGY 4921
Cdd:PRK10070  197 PLIRTEMQDELVKlQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDY 260
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
3842-4052 8.79e-22

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 96.89  E-value: 8.79e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHK-AVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL-QTDLSRVRMELGV 3919
Cdd:cd03245     3 IEFRNVSFSYPNQEiPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIrQLDPADLRRNIGY 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3920 CPqQDILLDNLTVREHLLLFasikAPQWTKKELHQQVNQTLQDVDLTQHQH-------KQTRALSGGLKRKLSLGIAFMG 3992
Cdd:cd03245    83 VP-QDVTLFYGTLRDNITLG----APLADDERILRAAELAGVTDFVNKHPNgldlqigERGRGLSGGQRQAVALARALLN 157
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3993 MSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLdEAEALSDRVAVLQHGRL 4052
Cdd:cd03245   158 DPPILLLDEPTSAMDMNSEERLKERLRQLLGDKTLIIITHRP-SLLDLVDRIIVMDSGRI 216
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
4688-4908 1.03e-21

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 96.55  E-value: 1.03e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKhyrrFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAG 4767
Cdd:cd03301     1 VELENVTK----RFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYI-----GGRDVTDLPPKD 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4768 VLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDI 4847
Cdd:cd03301    72 RDIAMVFQNYALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKV 151
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4848 LLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLG 4908
Cdd:cd03301   152 FLMDEPLSNLDAKLRVQMRAELKRLQQRlGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
4688-4902 1.42e-21

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 96.35  E-value: 1.42e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYRRffqnIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKML-------NGEVSLtSGHAIIRTPmgdAVDL 4760
Cdd:cd03224     1 LEVENLNAGYGK----SQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTImgllpprSGSIRF-DGRDITGLP---PHER 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4761 SSAGtagvlIGYCPQQDAL-------DELLTGWehlyyYCSLRGIPRQCIPEVAG---DLIRRLHleahadKPVATYSGG 4830
Cdd:cd03224    73 ARAG-----IGYVPEGRRIfpeltveENLLLGA-----YARRRAKRKARLERVYElfpRLKERRK------QLAGTLSGG 136
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4831 TKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:cd03224   137 EQQMLAIARALMSRPKLLLLDEPSEGLAPKIVEEIFEAIRELRDEGVTILLVEQNARFALEIADRAYVLERG 208
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
4692-4902 1.90e-21

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 99.38  E-value: 1.90e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGevsL---TSGHAIIrtpmgDAVDLSSAGTAGV 4768
Cdd:COG1135     6 NLSKTFPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINL---LerpTSGSVLV-----DGVDLTALSEREL 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4769 L-----IGYCPQQDALDELLTGWEHLYYycSLR--GIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALAL 4841
Cdd:COG1135    78 RaarrkIGMIFQHFNLLSSRTVAENVAL--PLEiaGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARAL 155
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 4842 VGKPDILLLDEPSSGMDPcskrylwQT------IMKEVRE--GCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:COG1135   156 ANNPKVLLCDEATSALDP-------ETtrsildLLKDINRelGLTIVLITHEMDVVRRICDRVAVLENG 217
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
4692-4905 2.25e-21

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 95.40  E-value: 2.25e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRffqNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGVlIG 4771
Cdd:cd03226     4 NISFSYKK---GTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILL-----NGKPIKAKERRKS-IG 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4772 YCPQqDALDELLTG--WEHLYYycSLRGIPRQciPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILL 4849
Cdd:cd03226    75 YVMQ-DVDYQLFTDsvREELLL--GLKELDAG--NEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLI 149
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 4850 LDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFK 4905
Cdd:cd03226   150 FDEPTSGLDYKNMERVGELIRELAAQGKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
3869-4116 3.63e-21

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 97.07  E-value: 3.63e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3869 QITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTD---LSRVRMELGVCPQQ-DILLDNLTVREHlLLFASIKA 3944
Cdd:PRK13639   29 EMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKYDkksLLEVRKTVGIVFQNpDDQLFAPTVEED-VAFGPLNL 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3945 pQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSL-GIAFMGmSRTVVLDEPTSGVDPCSRHSLWDILLKY-R 4022
Cdd:PRK13639  108 -GLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIaGILAMK-PEIIVLDEPTSGLDPMGASQIMKLLYDLnK 185
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4023 EGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPfclKEAYgqglrltltRQPSVLEAHDLKdMACVTSLIKIYIPqa 4102
Cdd:PRK13639  186 EGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTP---KEVF---------SDIETIRKANLR-LPRVAHLIEILNK-- 250
                         250
                  ....*....|....
gi 767944871 4103 flKDSSGSELTYTI 4116
Cdd:PRK13639  251 --EDNLPIKMGYTI 262
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
3847-4052 4.57e-21

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 100.76  E-value: 4.57e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVC--PQQD 3924
Cdd:PRK11288   10 IGKTFPGVKAL-DDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTTAALAAGVAiiYQEL 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3925 ILLDNLTVREHLLL------FASIKapqwtKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVV 3998
Cdd:PRK11288   89 HLVPEMTVAENLYLgqlphkGGIVN-----RRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNARVIA 163
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 3999 LDEPTSGVDpcSRHS--LWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:PRK11288  164 FDEPTSSLS--AREIeqLFRVIRELRaEGRVILYVSHRMEEIFALCDAITVFKDGRY 218
cbiO PRK13637
energy-coupling factor transporter ATPase;
3855-4058 4.59e-21

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 97.04  E-value: 4.59e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3855 KAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTD----LSRVRMELGVCPQQDilldnl 3930
Cdd:PRK13637   20 KKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDI-TDkkvkLSDIRKKVGLVFQYP------ 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3931 tvrEHLLLFASIK-----APQ---WTKKELHQQVNQTLQDVDLTQHQHKQTRA--LSGGLKRKLSL-GIAFMgMSRTVVL 3999
Cdd:PRK13637   93 ---EYQLFEETIEkdiafGPInlgLSEEEIENRVKRAMNIVGLDYEDYKDKSPfeLSGGQKRRVAIaGVVAM-EPKILIL 168
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 4000 DEPTSGVDPCSRHslwDILLKYRE-----GRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK13637  169 DEPTAGLDPKGRD---EILNKIKElhkeyNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTP 229
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
3851-4052 4.72e-21

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 96.00  E-value: 4.72e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3851 YEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTI---ISMLTGLHP--PTSGTIIINGKNL---QTDLSRVRMELGVCPQ 3922
Cdd:PRK14239   14 YYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLlrsINRMNDLNPevTITGSIVYNGHNIyspRTDTVDLRKEIGMVFQ 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3923 QDilldN---LTVREHLLLFASIKAPQwTKKELHQQVNQTLQDV----DLTQHQHKQTRALSGGLKRKLSLGIAFMGMSR 3995
Cdd:PRK14239   94 QP----NpfpMSIYENVVYGLRLKGIK-DKQVLDEAVEKSLKGAsiwdEVKDRLHDSALGLSGGQQQRVCIARVLATSPK 168
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 3996 TVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:PRK14239  169 IILLDEPTSALDPISAGKIEETLLGLKDDYTMLLVTRSMQQASRISDRTGFFLDGDL 225
cbiO PRK13645
energy-coupling factor transporter ATPase;
3858-4059 5.33e-21

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 96.62  E-value: 5.33e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3858 VQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDL------SRVRMELGVC---PQQDILLD 3928
Cdd:PRK13645   27 LNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIPANLkkikevKRLRKEIGLVfqfPEYQLFQE 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3929 NLtvrEHLLLFASIKAPQwTKKELHQQVNQTLQDVDLTQHQHKQTR-ALSGGLKRKLSL-GIAFMGmSRTVVLDEPTSGV 4006
Cdd:PRK13645  107 TI---EKDIAFGPVNLGE-NKQEAYKKVPELLKLVQLPEDYVKRSPfELSGGQKRRVALaGIIAMD-GNTLVLDEPTGGL 181
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4007 DPCSRHSLWDILLKYRE--GRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPF 4059
Cdd:PRK13645  182 DPKGEEDFINLFERLNKeyKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPF 236
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
4670-4913 5.58e-21

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 100.65  E-value: 5.58e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4670 DVEKEEkrvfEGRTNGDILVLYNLSKHYRRFFQNII-AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHA 4748
Cdd:TIGR03269  266 EVEKEC----EVEVGEPIIKVRNVSKRYISVDRGVVkAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEV 341
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4749 IIRtpMGDA-VDLSSA-----GTAGVLIGYCPQQDALDELLTGWEHLYYYCSLrgiprqcipEVAGDLIRRLHL------ 4816
Cdd:TIGR03269  342 NVR--VGDEwVDMTKPgpdgrGRAKRYIGILHQEYDLYPHRTVLDNLTEAIGL---------ELPDELARMKAVitlkmv 410
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4817 ---EAHA----DKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEE 4888
Cdd:TIGR03269  411 gfdEEKAeeilDKYPDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEmEQTFIIVSHDMDF 490
                          250       260
                   ....*....|....*....|....*
gi 767944871  4889 CEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:TIGR03269  491 VLDVCDRAALMRDGKIVKIGDPEEI 515
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
4692-4915 5.73e-21

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 95.43  E-value: 5.73e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKhyrRFFQNIIaVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGVL-- 4769
Cdd:COG1127    10 NLTK---SFGDRVV-LDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILV-----DGQDITGLSEKELYel 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4770 ---IGYCPQQDALDELLTGWEHLYYYcsLR---GIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVG 4843
Cdd:COG1127    81 rrrIGMLFQGGALFDSLTVFENVAFP--LRehtDLSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALAL 158
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871 4844 KPDILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKN 4915
Cdd:COG1127   159 DPEILLYDEPTAGLDPITSAVIDELIRELRDElGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELLA 231
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
3852-4058 5.93e-21

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 94.87  E-value: 5.93e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3852 EGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT-DLSRVRMELGVCPQQDILLDNl 3930
Cdd:cd03244    14 PNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKiGLHDLRSRISIIPQDPVLFSG- 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3931 TVREHLLLFAsikapQWTKKELHqqvnQTLQDVDLTQHQHKQTRAL-----------SGGLKRKLSLGIAFMGMSRTVVL 3999
Cdd:cd03244    93 TIRSNLDPFG-----EYSDEELW----QALERVGLKEFVESLPGGLdtvveeggenlSVGQRQLLCLARALLRKSKILVL 163
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 4000 DEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDeAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:cd03244   164 DEATASVDPETDALIQKTIREAFKDCTVLTIAHRLD-TIIDSDRILVLDKGRVVEFDSP 221
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
3840-4052 6.58e-21

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 94.95  E-value: 6.58e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3840 PGVTLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL-QTDLSRV-RMEL 3917
Cdd:PRK11614    4 VMLSFDKVSAHY-GKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDItDWQTAKImREAV 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3918 GVCPQQDILLDNLTVREHLLL---FASikapqwtkKELHQQVNQTLQDV--DLTQHQHKQTRALSGGLKRKLSLGIAFMG 3992
Cdd:PRK11614   83 AIVPEGRRVFSRMTVEENLAMggfFAE--------RDQFQERIKWVYELfpRLHERRIQRAGTMSGGEQQMLAIGRALMS 154
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 3993 MSRTVVLDEPTSGVDPCSRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:PRK11614  155 QPRLLLLDEPSLGLAPIIIQQIFDTIEQLReQGMTIFLVEQNANQALKLADRGYVLENGHV 215
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
3840-4063 7.53e-21

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 98.10  E-value: 7.53e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3840 PGVTLVSVTKEYEGhKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLSRVRMELGV 3919
Cdd:PRK09452   13 PLVELRGISKSFDG-KEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDI-THVPAENRHVNT 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3920 CPQQDILLDNLTVREHlLLFAsIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVL 3999
Cdd:PRK09452   91 VFQSYALFPHMTVFEN-VAFG-LRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLL 168
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 4000 DEPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPFCLKE 4063
Cdd:PRK09452  169 DESLSALDYKLRKQMQNELkaLQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYE 234
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
4688-4902 1.37e-20

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 94.17  E-value: 1.37e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYRRFFQniiAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAG 4767
Cdd:cd03256     1 IEVENLSKTYPNGKK---ALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLI-----DGTDINKLKGKA 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4768 VL-----IGY-------CPQQDALDELLTGweHLYYYCSLRGIPRQCIPE---VAGDLIRRLHLEAHADKPVATYSGGTK 4832
Cdd:cd03256    73 LRqlrrqIGMifqqfnlIERLSVLENVLSG--RLGRRSTWRSLFGLFPKEekqRALAALERVGLLDKAYQRADQLSGGQQ 150
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4833 RKLSTALALVGKPDILLLDEPSSGMDPCSKRylwqTIMKEVRE-----GCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:cd03256   151 QRVAIARALMQQPKLILADEPVASLDPASSR----QVMDLLKRinreeGITVIVSLHQVDLAREYADRIVGLKDG 221
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
3855-4058 1.78e-20

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 94.47  E-value: 1.78e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3855 KAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRV-RMELGVCPQQDILLDNLTVR 3933
Cdd:PRK10575   24 RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAfARKVAYLPQQLPAAEGMTVR 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3934 EhllLFASIKAPqWT------KKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVD 4007
Cdd:PRK10575  104 E---LVAIGRYP-WHgalgrfGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALD 179
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 4008 PCsrHSLwDIL-----LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK10575  180 IA--HQV-DVLalvhrLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTP 232
cbiO PRK13644
energy-coupling factor transporter ATPase;
3842-4106 1.81e-20

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 94.67  E-value: 1.81e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQ--TDLSRVRMELGV 3919
Cdd:PRK13644    2 IRLENVSYSYPDGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGdfSKLQGIRKLVGI 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3920 CPQQ-DILLDNLTVREHLLLfasikAPQ---WTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSR 3995
Cdd:PRK13644   82 VFQNpETQFVGRTVEEDLAF-----GPEnlcLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPE 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3996 TVVLDEPTSGVDPCSRHSLWDILLK-YREGRTIIFTTHHLDEAEAlSDRVAVLQHGRLRCCG-PPFCLKEAYGQGLRLTL 4073
Cdd:PRK13644  157 CLIFDEVTSMLDPDSGIAVLERIKKlHEKGKTIVYITHNLEELHD-ADRIIVMDRGKIVLEGePENVLSDVSLQTLGLTP 235
                         250       260       270
                  ....*....|....*....|....*....|....
gi 767944871 4074 trqPSVLE-AHDLKDMACVTSLIKIYIPQAFLKD 4106
Cdd:PRK13644  236 ---PSLIElAENLKMHGVVIPWENTSSPSSFAEE 266
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
3852-4058 2.31e-20

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 94.29  E-value: 2.31e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3852 EGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTD-LSRVRMELGVCPQQDillDN- 3929
Cdd:PRK13632   19 NSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKEnLKEIRKKIGIIFQNP---DNq 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3930 ---LTVREHLLLfaSIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGV 4006
Cdd:PRK13632   96 figATVEDDIAF--GLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDESTSML 173
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 767944871 4007 DPCSRHSLWDILLKYREGR--TIIFTTHHLDEAeALSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK13632  174 DPKGKREIKKIMVDLRKTRkkTLISITHDMDEA-ILADKVIVFSEGKLIAQGKP 226
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
4667-4853 2.55e-20

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 98.60  E-value: 2.55e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4667 KDTDVEKEEKRVF-----EGRTNGDILVLYNLSKHY--RRFFQniiavqDISLGIPKGECFGLLGVNGAGKSTTFKMLNG 4739
Cdd:COG0488   290 EREEPPRRDKTVEirfppPERLGKKVLELEGLSKSYgdKTLLD------DLSLRIDRGDRIGLIGPNGAGKSTLLKLLAG 363
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4740 EVSLTSGHAIIrtpmgdavdlssaGTaGVLIGYCPQ-QDALDELLTGWEHLyyycsLRGIPRQCIPEVAGdlirrlHLEA 4818
Cdd:COG0488   364 ELEPDSGTVKL-------------GE-TVKIGYFDQhQEELDPDKTVLDEL-----RDGAPGGTEQEVRG------YLGR 418
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 767944871 4819 ------HADKPVATYSGGTKRKLSTALALVGKPDILLLDEP 4853
Cdd:COG0488   419 flfsgdDAFKPVGVLSGGEKARLALAKLLLSPPNVLLLDEP 459
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
4688-4902 2.72e-20

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 90.95  E-value: 2.72e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHyrrfFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAgtag 4767
Cdd:cd03216     1 LELRGITKR----FGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVD---GKEVSFASP---- 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4768 vligycpqQDALDelltgwehlyyycslRGIprQCIPEvagdlirrlhleahadkpvatYSGGTKRKLSTALALVGKPDI 4847
Cdd:cd03216    70 --------RDARR---------------AGI--AMVYQ---------------------LSVGERQMVEIARALARNARL 103
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4848 LLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:cd03216   104 LILDEPTAALTPAEVERLFKVIRRLRAQGVAVIFISHRLDEVFEIADRVTVLRDG 158
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
4690-4902 2.93e-20

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 95.64  E-value: 2.93e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4690 LYNLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGVL 4769
Cdd:PRK11153    4 LKNISKVFPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLV-----DGQDLTALSEKELR 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4770 -----IGYCPQqdaldelltgweHLYYYCS------------LRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTK 4832
Cdd:PRK11153   79 karrqIGMIFQ------------HFNLLSSrtvfdnvalpleLAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQK 146
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4833 RKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQtIMKEV-RE-GCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:PRK11153  147 QRVAIARALASNPKVLLCDEATSALDPATTRSILE-LLKDInRElGLTIVLITHEMDVVKRICDRVAVIDAG 217
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
4708-4915 3.03e-20

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 92.95  E-value: 3.03e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4708 QDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGVL-----IGYCPQQDALDEL 4782
Cdd:cd03261    17 KGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLI-----DGEDISGLSEAELYrlrrrMGMLFQSGALFDS 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4783 LTGWEH----LYYYCSLrgiPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMD 4858
Cdd:cd03261    92 LTVFENvafpLREHTRL---SEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLLYDEPTAGLD 168
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4859 PCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKN 4915
Cdd:cd03261   169 PIASGVIDDLIRSLKKElGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELRA 226
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
3847-4052 3.10e-20

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 93.92  E-value: 3.10e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGL---------HPPTSGTIIINGKNLQTDLSRVRMEL 3917
Cdd:PRK09984   10 LAKTFNQHQAL-HAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLitgdksagsHIELLGRTVQREGRLARDIRKSRANT 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3918 GVCPQQDILLDNLTVREHLLLFASIKAP------QWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFM 3991
Cdd:PRK09984   89 GYIFQQFNLVNRLSVLENVLIGALGSTPfwrtcfSWFTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQRVAIARALM 168
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871 3992 GMSRTVVLDEPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:PRK09984  169 QQAKVILADEPIASLDPESARIVMDTLrdINQNDGITVVVTLHQVDYALRYCERIVALRQGHV 231
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
3830-4056 3.21e-20

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 98.74  E-value: 3.21e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3830 NREGELEGSAPGVTLVSVTKEY-EGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT 3908
Cdd:PRK11160  327 PTTSTAAADQVSLTLNNVSFTYpDQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIAD 406
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3909 -DLSRVRMELGVCPQQdILLDNLTVREHLLLfasiKAPQWTKKELHqqvnQTLQDVDLTQH-QHKQT---------RALS 3977
Cdd:PRK11160  407 ySEAALRQAISVVSQR-VHLFSATLRDNLLL----AAPNASDEALI----EVLQQVGLEKLlEDDKGlnawlgeggRQLS 477
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 3978 GGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEALsDRVAVLQHGRLRCCG 4056
Cdd:PRK11160  478 GGEQRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEHAQNKTVLMITHRLTGLEQF-DRICVMDNGQIIEQG 555
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
3872-4058 3.31e-20

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 98.97  E-value: 3.31e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3872 ALLGTNGAGKTTIISMLTGLHPP---TSGTIIINGKNLQTDLSRVRMelGVCPQQDILLDNLTVREHLLLFASIKAP-QW 3947
Cdd:TIGR00955   55 AVMGSSGAGKTTLMNALAFRSPKgvkGSGSVLLNGMPIDAKEMRAIS--AYVQQDDLFIPTLTVREHLMFQAHLRMPrRV 132
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3948 TKKELHQQVNQTLQDVDLTQHQH------KQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKY 4021
Cdd:TIGR00955  133 TKKEKRERVDEVLQALGLRKCANtrigvpGRVKGLSGGERKRLAFASELLTDPPLLFCDEPTSGLDSFMAYSVVQVLKGL 212
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 767944871  4022 -REGRTIIFTTH----HLDEaeaLSDRVAVLQHGRLRCCGPP 4058
Cdd:TIGR00955  213 aQKGKTIICTIHqpssELFE---LFDKIILMAEGRVAYLGSP 251
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
3846-4050 3.65e-20

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 97.81  E-value: 3.65e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3846 SVTKEYEGhKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNlQTDLSRVRM-ELGV--CPQ 3922
Cdd:PRK15439   16 SISKQYSG-VEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNP-CARLTPAKAhQLGIylVPQ 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3923 QDILLDNLTVREHLLLfaSIKAPQWTKKELHQQVNQTLQDVDLtqhqHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEP 4002
Cdd:PRK15439   94 EPLLFPNLSVKENILF--GLPKRQASMQKMKQLLAALGCQLDL----DSSAGSLEVADRQIVEILRGLMRDSRILILDEP 167
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 767944871 4003 TSGVDPCSRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVLQHG 4050
Cdd:PRK15439  168 TASLTPAETERLFSRIRELLaQGVGIVFISHKLPEIRQLADRISVMRDG 216
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
3852-4076 4.51e-20

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 93.65  E-value: 4.51e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3852 EGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL-QTDLSRVRMELGVCPQQ-DILLDN 3929
Cdd:PRK13647   16 DGTKAL-KGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVnAENEKWVRSKVGLVFQDpDDQVFS 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3930 LTVREHLLLfasikAPQ---WTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSL-GIAFMgMSRTVVLDEPTSG 4005
Cdd:PRK13647   95 STVWDDVAF-----GPVnmgLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIaGVLAM-DPDVIVLDEPMAY 168
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4006 VDPCSRHSLWDILLK-YREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPFCL--KEAYGQ-GLRLTLTRQ 4076
Cdd:PRK13647  169 LDPRGQETLMEILDRlHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKSLLtdEDIVEQaGLRLPLVAQ 243
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
3858-4058 5.31e-20

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 96.26  E-value: 5.31e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3858 VQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL----QTDLSRVR-MELGVCPQQDILLDNLTV 3932
Cdd:PRK10070   44 VKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIakisDAELREVRrKKIAMVFQSFALMPHMTV 123
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3933 REHL---LLFASIKAPQWTKKELhqqvnQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPC 4009
Cdd:PRK10070  124 LDNTafgMELAGINAEERREKAL-----DALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPL 198
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4010 SRHSLWDILLKY--REGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK10070  199 IRTEMQDELVKLqaKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTP 249
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
4687-4902 5.83e-20

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 92.03  E-value: 5.83e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTA 4766
Cdd:COG1136     4 LLELRNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLI-----DGQDISSLSER 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4767 GV------LIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALA 4840
Cdd:COG1136    79 ELarlrrrHIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARA 158
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871 4841 LVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSmEECEALCTRLAIMVNG 4902
Cdd:COG1136   159 LVNRPKLILADEPTGNLDSKTGEEVLELLRELNRElGTTIVMVTHD-PELAARADRVIRLRDG 220
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
3842-4067 6.18e-20

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 95.17  E-value: 6.18e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLSrvrmelgvCP 3921
Cdd:PRK11432    7 VVLKNITKRF-GSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDV-THRS--------IQ 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QQDI--LLDNLTVREHLLLFASI----KAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSR 3995
Cdd:PRK11432   77 QRDIcmVFQSYALFPHMSLGENVgyglKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPK 156
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 3996 TVVLDEPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPfclKEAYGQ 4067
Cdd:PRK11432  157 VLLFDEPLSNLDANLRRSMREKIreLQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSP---QELYRQ 227
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
3847-4071 6.91e-20

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 93.16  E-value: 6.91e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKA-VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL-QTDLSRVRMELGVCPQQD 3924
Cdd:PRK13635   11 ISFRYPDAATyALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLsEETVWDVRRQVGMVFQNP 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3925 illDN----LTVREHLLlFA--SIKAPqwtKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSlgIAFMGMSR--T 3996
Cdd:PRK13635   91 ---DNqfvgATVQDDVA-FGleNIGVP---REEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVA--IAGVLALQpdI 161
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 3997 VVLDEPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAeALSDRVAVLQHGRLRCCGPPfclKEAYGQGLRL 4071
Cdd:PRK13635  162 IILDEATSMLDPRGRREVLETVrqLKEQKGITVLSITHDLDEA-AQADRVIVMNKGEILEEGTP---EEIFKSGHML 234
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
4698-4902 7.72e-20

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 91.47  E-value: 7.72e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4698 RRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSL-----TSGHAIIrtpmgDAVDLSSAGTAGVL--- 4769
Cdd:cd03260     7 NVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLipgapDEGEVLL-----DGKDIYDLDVDVLElrr 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4770 -IGYCPQQDALDELlTGWEHLYYYCSLRGI-PRQCIPEVAGDLIRRLHL-EAHADKPVATY-SGGTKRKLSTALALVGKP 4845
Cdd:cd03260    82 rVGMVFQKPNPFPG-SIYDNVAYGLRLHGIkLKEELDERVEEALRKAALwDEVKDRLHALGlSGGQQQRLCLARALANEP 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4846 DILLLDEPSSGMDPCSKRYLWQTIMkEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:cd03260   161 EVLLLDEPTSALDPISTAKIEELIA-ELKKEYTIVIVTHNMQQAARVADRTAFLLNG 216
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
3858-4051 8.49e-20

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 92.36  E-value: 8.49e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3858 VQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCPQ-QDI-LLDNLTVREH 3935
Cdd:PRK11300   21 VNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIARMGVVRTfQHVrLFREMTVIEN 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3936 LL----------LFAS-IKAPQWTKKELH--QQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEP 4002
Cdd:PRK11300  101 LLvaqhqqlktgLFSGlLKTPAFRRAESEalDRAATWLERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILMLDEP 180
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4003 TSGVDPCSRHSLWDILLKYRE--GRTIIFTTHHLDEAEALSDRVAVLQHGR 4051
Cdd:PRK11300  181 AAGLNPKETKELDELIAELRNehNVTVLLIEHDMKLVMGISDRIYVVNQGT 231
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
3846-4058 8.74e-20

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 92.08  E-value: 8.74e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3846 SVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIING---KNLQTDLSRVRMELGVCPQ 3922
Cdd:PRK09493    6 NVSKHF-GPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGlkvNDPKVDERLIRQEAGMVFQ 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3923 QDILLDNLTVREHLLlFASIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEP 4002
Cdd:PRK09493   85 QFYLFPHLTALENVM-FGPLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLFDEP 163
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4003 TSGVDPCSRHSLWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK09493  164 TSALDPELRHEVLKVMQDLaEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDP 220
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
4705-4903 1.36e-19

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 90.79  E-value: 1.36e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4705 IAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEV---SLTSGHAIIRtpmGDAvdlSSAGTAGVLIGYCPQQDALDE 4781
Cdd:cd03234    21 RILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVeggGTTSGQILFN---GQP---RKPDQFQKCVAYVRQDDILLP 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4782 LLTGWEHLYYYCSLRGiPR-----QCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSG 4856
Cdd:cd03234    95 GLTVRETLTYTAILRL-PRkssdaIRKKRVEDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSG 173
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 767944871 4857 MDPCSKRYLWQTIMKEVREGCAAVLTSHS-MEECEALCTRLAIMVNGS 4903
Cdd:cd03234   174 LDSFTALNLVSTLSQLARRNRIVILTIHQpRSDLFRLFDRILLLSSGE 221
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
3860-4087 2.77e-19

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 93.25  E-value: 2.77e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3860 DLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT-----DLSRVRMELGVCPQQDILLDNLTVRE 3934
Cdd:TIGR02142   15 DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDsrkgiFLPPEKRRIGYVFQEARLFPHLSVRG 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3935 HLLLFASIKAPQWTKKELhQQVNQTLQDVDLTQhqhKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSL 4014
Cdd:TIGR02142   95 NLRYGMKRARPSERRISF-ERVIELLGIGHLLG---RLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEI 170
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4015 WDILLKYRE--GRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPfclKEAYGQGLRLTLTRQP------SVLEAHDLK 4086
Cdd:TIGR02142  171 LPYLERLHAefGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPI---AEVWASPDLPWLAREDqgslieGVVAEHDQH 247

                   .
gi 767944871  4087 D 4087
Cdd:TIGR02142  248 Y 248
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
3843-4058 2.91e-19

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 90.53  E-value: 2.91e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3843 TLVSVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGknlqtdlsRVR--MELGVc 3920
Cdd:COG1134    27 LLLRRRRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNG--------RVSalLELGA- 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3921 pqqdILLDNLTVREHLLLFASIkapqwtkkeL---HQQVNQTLQDV----DLTQHQHKQTRALSGGLKRKLSLGIAFMgm 3993
Cdd:COG1134    98 ----GFHPELTGRENIYLNGRL---------LglsRKEIDEKFDEIvefaELGDFIDQPVKTYSSGMRARLAFAVATA-- 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3994 srtvvldeptsgVDPcsrhslwDILL----------------------KYREGRTIIFTTHHLDEAEALSDRVAVLQHGR 4051
Cdd:COG1134   163 ------------VDP-------DILLvdevlavgdaafqkkclarireLRESGRTVIFVSHSMGAVRRLCDRAIWLEKGR 223

                  ....*..
gi 767944871 4052 LRCCGPP 4058
Cdd:COG1134   224 LVMDGDP 230
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
4699-4925 3.54e-19

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 92.88  E-value: 3.54e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4699 RFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTtfKMLNGEVSltsGHAIIRTPMGDAVDLSSAGTAGVLIG-YCPQQD 4777
Cdd:NF000106   21 KHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**R--GALPAHV*---GPDAGRRPWRF*TWCANRRALRRTIG*HRPVR* 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4778 ALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGM 4857
Cdd:NF000106   96 GRRESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGL 175
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4858 DPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKNRFGdGYTVKV 4925
Cdd:NF000106  176 DPRTRNEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVG-GRTLQI 242
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
3842-4051 4.06e-19

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 89.60  E-value: 4.06e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHK-AVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT-DLSRVRMELGV 3919
Cdd:cd03251     1 VEFKNVTFRYPGDGpPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDyTLASLRRQIGL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3920 CpQQDILLDNLTVREHLllfaSIKAPQWTKKE---------LHQQVNQTLQDVDlTQHQHKQTRaLSGGLKRKLSLGIAF 3990
Cdd:cd03251    81 V-SQDVFLFNDTVAENI----AYGRPGATREEveeaaraanAHEFIMELPEGYD-TVIGERGVK-LSGGQRQRIAIARAL 153
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 3991 MGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEAlSDRVAVLQHGR 4051
Cdd:cd03251   154 LKDPPILILDEATSALDTESERLVQAALERLMKNRTTFVIAHRLSTIEN-ADRIVVLEDGK 213
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
4688-4899 4.49e-19

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 90.31  E-value: 4.49e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTAG 4767
Cdd:COG4525     4 LTVRHVSVRYPGGGQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLD---GVPVTGPGADRGV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4768 VLigycpQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDI 4847
Cdd:COG4525    81 VF-----QKDALLPWLNVLDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRF 155
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 767944871 4848 LLLDEPSSGMDPCSKRYLwQTIMKEV--REGCAAVLTSHSMEECEALCTRLAIM 4899
Cdd:COG4525   156 LLMDEPFGALDALTREQM-QELLLDVwqRTGKGVFLITHSVEEALFLATRLVVM 208
cbiO PRK13643
energy-coupling factor transporter ATPase;
3860-4058 5.00e-19

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 90.95  E-value: 5.00e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3860 DLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGT-----IIINGKNLQTDLSRVRMELGVC---PQQDILldnlt 3931
Cdd:PRK13643   24 DIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKvtvgdIVVSSTSKQKEIKPVRKKVGVVfqfPESQLF----- 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3932 vrEHLLLFASIKAPQ---WTKKELHQQVNQTLQDVDLTQH-QHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVD 4007
Cdd:PRK13643   99 --EETVLKDVAFGPQnfgIPKEKAEKIAAEKLEMVGLADEfWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLD 176
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4008 PCSRHSLWDILLK-YREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK13643  177 PKARIEMMQLFESiHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTP 228
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
3852-4052 6.85e-19

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 87.27  E-value: 6.85e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3852 EGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL-QTDLSRVRMELGVCPQQDILLDNl 3930
Cdd:cd03246    12 GAEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADIsQWDPNELGDHVGYLPQDDELFSG- 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3931 TVREHLLlfasikapqwtkkelhqqvnqtlqdvdltqhqhkqtralSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCS 4010
Cdd:cd03246    91 SIAENIL---------------------------------------SGGQRQRLGLARALYGNPRILVLDEPNSHLDVEG 131
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 767944871 4011 RHSLWDIL--LKYReGRTIIFTTHHLdEAEALSDRVAVLQHGRL 4052
Cdd:cd03246   132 ERALNQAIaaLKAA-GATRIVIAHRP-ETLASADRILVLEDGRV 173
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
3835-4058 9.01e-19

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 89.81  E-value: 9.01e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3835 LEGSAPGVTLVSVTKEYEGHKA-VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL-QTDLSR 3912
Cdd:PRK13648    1 MEDKNSIIVFKNVSFQYQSDASfTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAItDDNFEK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3913 VRMELGVCPQQ------------DIL--LDNLTVrehlllfasikapqwTKKELHQQVNQTLQDVDLTQHQHKQTRALSG 3978
Cdd:PRK13648   81 LRKHIGIVFQNpdnqfvgsivkyDVAfgLENHAV---------------PYDEMHRRVSEALKQVDMLERADYEPNALSG 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3979 GLKRKLSL-GIAFMGMSrTVVLDEPTSGVDPCSRHSLWDILLKYREGR--TIIFTTHHLDEAeALSDRVAVLQHGRLRCC 4055
Cdd:PRK13648  146 GQKQRVAIaGVLALNPS-VIILDEATSMLDPDARQNLLDLVRKVKSEHniTIISITHDLSEA-MEADHVIVMNKGTVYKE 223

                  ...
gi 767944871 4056 GPP 4058
Cdd:PRK13648  224 GTP 226
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
4695-4915 1.03e-18

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 93.31  E-value: 1.03e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4695 KHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLSSAGTAGVLIGYcp 4774
Cdd:PRK09700    9 AGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLAAQLGIGIIY-- 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4775 QQDALDELLTGWEHLYY-------YCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDI 4847
Cdd:PRK09700   87 QELSVIDELTVLENLYIgrhltkkVCGVNIIDWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDAKV 166
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 4848 LLLDEPSSGMDPCSKRYLWqTIMKEVR-EGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKN 4915
Cdd:PRK09700  167 IIMDEPTSSLTNKEVDYLF-LIMNQLRkEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVSDVSN 234
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
3847-4052 1.10e-18

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 88.44  E-value: 1.10e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL-QTDLSRVRMELGVCPqQDI 3925
Cdd:cd03253     6 VTFAYDPGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIrEVTLDSLRRAIGVVP-QDT 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3926 LLDNLTVREHLL---LFAS----IKAPQwtKKELHQQVNQTLQDVDlTQHQHKQTRaLSGGLKRKLSLGIAFMGMSRTVV 3998
Cdd:cd03253    85 VLFNDTIGYNIRygrPDATdeevIEAAK--AAQIHDKIMRFPDGYD-TIVGERGLK-LSGGEKQRVAIARAILKNPPILL 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 767944871 3999 LDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAeALSDRVAVLQHGRL 4052
Cdd:cd03253   161 LDEATSALDTHTEREIQAALRDVSKGRTTIVIAHRLSTI-VNADKIIVLKDGRI 213
cbiO PRK13640
energy-coupling factor transporter ATPase;
3855-4058 1.32e-18

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 89.47  E-value: 1.32e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3855 KAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTS---GTIIINGKNLQTD-LSRVRMELGVCPQQDillDN- 3929
Cdd:PRK13640   20 KPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDnpnSKITVDGITLTAKtVWDIREKVGIVFQNP---DNq 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3930 ---LTVREHLLLfaSIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSL-GIAFMGmSRTVVLDEPTSG 4005
Cdd:PRK13640   97 fvgATVGDDVAF--GLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIaGILAVE-PKIIILDESTSM 173
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4006 VDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEaLSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK13640  174 LDPAGKEQILKLIrkLKKKNNLTVISITHDIDEAN-MADQVLVLDDGKLLAQGSP 227
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
3847-4058 1.40e-18

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 89.48  E-value: 1.40e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL-QTDLSRVRMELGVCPQQ-D 3924
Cdd:PRK13652    9 LCYSYSGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPItKENIREVRKFVGLVFQNpD 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3925 ILLDNLTVrEHLLLFASIKAPQWTKKELHqQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSL-GIAFMgMSRTVVLDEPT 4003
Cdd:PRK13652   89 DQIFSPTV-EQDIAFGPINLGLDEETVAH-RVSSALHMLGLEELRDRVPHHLSGGEKKRVAIaGVIAM-EPQVLVLDEPT 165
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4004 SGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK13652  166 AGLDPQGVKELIDFLndLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTV 222
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
3857-4052 1.66e-18

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 93.65  E-value: 1.66e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3857 VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT-DLSRVRMELGVCPQQDILLDNlTVREH 3935
Cdd:TIGR01193  489 ILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDiDRHTLRQFINYLPQEPYIFSG-SILEN 567
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3936 LLLFASikaPQWTKKELHQQVNQTLQDVDLTQ-HQHKQTR------ALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDP 4008
Cdd:TIGR01193  568 LLLGAK---ENVSQDEIWAACEIAEIKDDIENmPLGYQTElseegsSISGGQKQRIALARALLTDSKVLILDESTSNLDT 644
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 767944871  4009 CSRHSLWDILLKYREgRTIIFTTHHLDEAEaLSDRVAVLQHGRL 4052
Cdd:TIGR01193  645 ITEKKIVNNLLNLQD-KTIIFVAHRLSVAK-QSDKIIVLDHGKI 686
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
3854-4050 2.29e-18

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 88.31  E-value: 2.29e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3854 HKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQ-TDLS----RVRM-----ELGVCPQQ 3923
Cdd:PRK15112   25 TVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHfGDYSyrsqRIRMifqdpSTSLNPRQ 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3924 DI--LLDnltvrEHLLLFASIKAPqwtkkELHQQVNQTLQDVDL-TQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLD 4000
Cdd:PRK15112  105 RIsqILD-----FPLRLNTDLEPE-----QREKQIIETLRQVGLlPDHASYYPHMLAPGQKQRLGLARALILRPKVIIAD 174
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4001 EPTSGVDPCSRHSLWDILLKYREGRTI--IFTTHHLDEAEALSDRVAVLQHG 4050
Cdd:PRK15112  175 EALASLDMSMRSQLINLMLELQEKQGIsyIYVTQHLGMMKHISDQVLVMHQG 226
cbiO PRK13641
energy-coupling factor transporter ATPase;
3860-4052 2.38e-18

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 88.73  E-value: 2.38e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3860 DLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGK--NLQT---DLSRVRMELGVCPQ--QDILLDNlTV 3932
Cdd:PRK13641   25 NISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYhiTPETgnkNLKKLRKKVSLVFQfpEAQLFEN-TV 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3933 REHLLL----F------ASIKAPQWTKKelhqqvnqtlqdVDL-TQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDE 4001
Cdd:PRK13641  104 LKDVEFgpknFgfsedeAKEKALKWLKK------------VGLsEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDE 171
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4002 PTSGVDPCSRHSLWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:PRK13641  172 PAAGLDPEGRKEMMQLFKDYqKAGHTVILVTHNMDDVAEYADDVLVLEHGKL 223
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
3842-4056 2.60e-18

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 87.54  E-value: 2.60e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHKAVV-QDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT-DLSRVRMELGV 3919
Cdd:cd03252     1 ITFEHVRFRYKPDGPVIlDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALaDPAWLRRQVGV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3920 CPQQDILLdNLTVREHLLL------------FASIKAPQWTKKELHQQVNQTLQDvdltqhqhkQTRALSGGLKRKLSLG 3987
Cdd:cd03252    81 VLQENVLF-NRSIRDNIALadpgmsmervieAAKLAGAHDFISELPEGYDTIVGE---------QGAGLSGGQRQRIAIA 150
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 3988 IAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEAlSDRVAVLQHGRLRCCG 4056
Cdd:cd03252   151 RALIHNPRILIFDEATSALDYESEHAIMRNMHDICAGRTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQG 218
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
3847-4052 2.84e-18

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 89.34  E-value: 2.84e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVVQ---DLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPP---TSGTIIINGKNLqTDLSRVRM----- 3915
Cdd:COG0444     7 LKVYFPTRRGVVKavdGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGEDL-LKLSEKELrkirg 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3916 -ELGVCPQ------------QDILLDnlTVREHLLLfasikapqwTKKELHQQVNQTLQDVDLTQ---------HQhkqt 3973
Cdd:COG0444    86 rEIQMIFQdpmtslnpvmtvGDQIAE--PLRIHGGL---------SKAEARERAIELLERVGLPDperrldrypHE---- 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3974 raLSGGLKRKLslGIAfMGMS---RTVVLDEPTSGVDPCSRHSLWDILLKYRE--GRTIIFTTHHLDEAEALSDRVAVLQ 4048
Cdd:COG0444   151 --LSGGMRQRV--MIA-RALAlepKLLIADEPTTALDVTIQAQILNLLKDLQRelGLAILFITHDLGVVAEIADRVAVMY 225

                  ....
gi 767944871 4049 HGRL 4052
Cdd:COG0444   226 AGRI 229
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
3853-4052 3.29e-18

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 91.62  E-value: 3.29e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGV--CP----QQDIL 3926
Cdd:COG1129   263 SVGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRSPRDAIRAGIayVPedrkGEGLV 342
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3927 LDnLTVREHLLLfASIKAPQW----TKKELHQQVNQTLQDVDL-TQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDE 4001
Cdd:COG1129   343 LD-LSIRENITL-ASLDRLSRggllDRRRERALAEEYIKRLRIkTPSPEQPVGNLSGGNQQKVVLAKWLATDPKVLILDE 420
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4002 PTSGVDPCSRHSLWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:COG1129   421 PTRGIDVGAKAEIYRLIRELaAEGKAVIVISSELPELLGLSDRILVMREGRI 472
cbiO PRK13649
energy-coupling factor transporter ATPase;
3841-4058 4.58e-18

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 87.88  E-value: 4.58e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3841 GVTLVSVTKEYEG----HKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT-----DLS 3911
Cdd:PRK13649    2 GINLQNVSYTYQAgtpfEGRALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITStsknkDIK 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3912 RVRMELGVCPQ--QDILLDNlTVREHLLLfasikAPQ---WTKKELHQQVNQTLQDVDLTQHQ-HKQTRALSGGLKRKLS 3985
Cdd:PRK13649   82 QIRKKVGLVFQfpESQLFEE-TVLKDVAF-----GPQnfgVSQEEAEALAREKLALVGISESLfEKNPFELSGGQMRRVA 155
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 3986 L-GIAFMGMSrTVVLDEPTSGVDPCSRHSLWDILLK-YREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK13649  156 IaGILAMEPK-ILVLDEPTAGLDPKGRKELMTLFKKlHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKP 229
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
4707-4902 5.75e-18

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 85.30  E-value: 5.75e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSL--TSGHAIIRTPMGDAVDLSSagtagvLIGYCPQQDALDELLT 4784
Cdd:cd03213    25 LKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGlgVSGEVLINGRPLDKRSFRK------IIGYVPQDDILHPTLT 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4785 GWEHLYYYCSLRGIprqcipevagdlirrlhleahadkpvatySGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRY 4864
Cdd:cd03213    99 VRETLMFAAKLRGL-----------------------------SGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQ 149
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 767944871 4865 LWQTIMKEVREGCAAVLTSHS-MEECEALCTRLAIMVNG 4902
Cdd:cd03213   150 VMSLLRRLADTGRTIICSIHQpSSEIFELFDKLLLLSQG 188
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
4687-4887 6.79e-18

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 85.87  E-value: 6.79e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYRrffQNIIAVQDISLGIPKGE-CFgLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGT 4765
Cdd:COG2884     1 MIRFENVSKRYP---GGREALSDVSLEIEKGEfVF-LTGPSGAGKSTLLKLLYGEERPTSGQVLV-----NGQDLSRLKR 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4766 AGVL-----IGYCPqQDA--LDElLTGWEHLYYycSLR--GIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLS 4836
Cdd:COG2884    72 REIPylrrrIGVVF-QDFrlLPD-RTVYENVAL--PLRvtGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVA 147
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4837 TALALVGKPDILLLDEPSSGMDPCSKRYLWQtIMKEV-REGCAAVLTSHSME 4887
Cdd:COG2884   148 IARALVNRPELLLADEPTGNLDPETSWEIME-LLEEInRRGTTVLIATHDLE 198
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
3831-4058 7.12e-18

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 91.02  E-value: 7.12e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3831 REGELEGSAPGVTLVSVTKEY----EGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL 3906
Cdd:TIGR03269  269 KECEVEVGEPIIKVRNVSKRYisvdRGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRVGDE 348
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3907 QTDLS--------RVRMELGVCPQQDILLDNLTVREHLLLFASIKAPqwtkKEL-HQQVNQTLQDVDLTQHQ-----HKQ 3972
Cdd:TIGR03269  349 WVDMTkpgpdgrgRAKRYIGILHQEYDLYPHRTVLDNLTEAIGLELP----DELaRMKAVITLKMVGFDEEKaeeilDKY 424
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3973 TRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYRE--GRTIIFTTHHLDEAEALSDRVAVLQHG 4050
Cdd:TIGR03269  425 PDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREemEQTFIIVSHDMDFVLDVCDRAALMRDG 504

                   ....*...
gi 767944871  4051 RLRCCGPP 4058
Cdd:TIGR03269  505 KIVKIGDP 512
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
3838-4057 8.05e-18

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 86.86  E-value: 8.05e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3838 SAPGVTLVSVTKEYE-GHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRme 3916
Cdd:PRK15056    3 QQAGIVVNDVTVTWRnGHTAL-RDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQALQKNL-- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3917 LGVCPQQD-------ILLDNLTVREHLLLFASIKAPqwtKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIA 3989
Cdd:PRK15056   80 VAYVPQSEevdwsfpVLVEDVVMMGRYGHMGWLRRA---KKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARA 156
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 3990 FMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDrVAVLQHGRLRCCGP 4057
Cdd:PRK15056  157 IAQQGQVILLDEPFTGVDVKTEARIISLLRELRdEGKTMLVSTHNLGSVTEFCD-YTVMVKGTVLASGP 224
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
4709-4903 8.31e-18

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 85.42  E-value: 8.31e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4709 DISLGIPkGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIR-TPMGDA---VDLSSAGTAgvlIGYCPQQDALDELLT 4784
Cdd:cd03297    16 KIDFDLN-EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNgTVLFDSrkkINLPPQQRK---IGLVFQQYALFPHLN 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4785 GWEHLYYycSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDpcskRY 4864
Cdd:cd03297    92 VRENLAF--GLKRKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALD----RA 165
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 767944871 4865 LWQTIMKEVRE-----GCAAVLTSHSMEECEALCTRLAIMVNGS 4903
Cdd:cd03297   166 LRLQLLPELKQikknlNIPVIFVTHDLSEAEYLADRIVVMEDGR 209
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
3853-4041 9.86e-18

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 84.72  E-value: 9.86e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGknlqTDLSRVRMElgvcPQQDIL----LD 3928
Cdd:TIGR01189   11 GERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNG----TPLAEQRDE----PHENILylghLP 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3929 ----NLTVREHLLLFASIKAPQwtkkelHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTS 4004
Cdd:TIGR01189   83 glkpELSALENLHFWAAIHGGA------QRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTT 156
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 767944871  4005 GVDPCSRHSLWDILLKYRE-GRTIIFTTHH---LDEAEALS 4041
Cdd:TIGR01189  157 ALDKAGVALLAGLLRAHLArGGIVLLTTHQdlgLVEARELR 197
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
3854-4052 1.54e-17

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 84.83  E-value: 1.54e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3854 HKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL-QTDLSRVRMELGVCPQQDILL----- 3927
Cdd:cd03248    26 DTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPIsQYEHKYLHSKVSLVGQEPVLFarslq 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3928 DNLTVREHLLLFASIKAPQwTKKELHQQVNQTLQDVDlTQHQHKQTRaLSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVD 4007
Cdd:cd03248   106 DNIAYGLQSCSFECVKEAA-QKAHAHSFISELASGYD-TEVGEKGSQ-LSGGQKQRVAIARALIRNPQVLILDEATSALD 182
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 767944871 4008 PCSRHSLWDILLKYREGRTIIFTTHHLDEAEAlSDRVAVLQHGRL 4052
Cdd:cd03248   183 AESEQQVQQALYDWPERRTVLVIAHRLSTVER-ADQILVLDGGRI 226
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
3853-4033 1.56e-17

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 84.08  E-value: 1.56e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCPQQDILLDNLTV 3932
Cdd:cd03231    11 DGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSIARGLLYLGHAPGIKTTLSV 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3933 REHLLLFASIKApqwtkkelHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRH 4012
Cdd:cd03231    91 LENLRFWHADHS--------DEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVA 162
                         170       180
                  ....*....|....*....|..
gi 767944871 4013 SLWDILLKYRE-GRTIIFTTHH 4033
Cdd:cd03231   163 RFAEAMAGHCArGGMVVLTTHQ 184
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
4687-4902 1.84e-17

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 89.32  E-value: 1.84e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHyrrfFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTA 4766
Cdd:COG3845     5 ALELRGITKR----FGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILID---GKPVRIRSPRDA 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4767 ---GvlIGYCPQQDALDELLTGWEHLYYycSLRGIPRQCIP-----EVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTA 4838
Cdd:COG3845    78 ialG--IGMVHQHFMLVPNLTVAENIVL--GLEPTKGGRLDrkaarARIRELSERYGLDVDPDAKVEDLSVGEQQRVEIL 153
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 4839 LALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:COG3845   154 KALYRGARILILDEPTAVLTPQEADELFEILRRLAAEGKSIIFITHKLREVMAIADRVTVLRRG 217
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
4687-4904 1.99e-17

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 89.31  E-value: 1.99e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHyrrfFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSS---A 4763
Cdd:COG1129     4 LLEMRGISKS----FGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLD---GEPVRFRSprdA 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4764 GTAGVLIGYcpQQDALDELLTGWEHLY---YYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALA 4840
Cdd:COG1129    77 QAAGIAIIH--QELNLVPNLSVAENIFlgrEPRRGGLIDWRAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARA 154
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4841 LVGKPDILLLDEPSSGMDPCSKRYLWQtIMKEVR-EGCAAVLTSHSMEECEALCTRLAIMVNGSF 4904
Cdd:COG1129   155 LSRDARVLILDEPTASLTEREVERLFR-IIRRLKaQGVAIIYISHRLDEVFEIADRVTVLRDGRL 218
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
4692-4911 2.66e-17

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 84.76  E-value: 2.66e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHyrrfFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAII--RTPMGDAVDL----SSAGT 4765
Cdd:PRK09493    6 NVSKH----FGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVdgLKVNDPKVDErlirQEAGM 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4766 AGVLIGYCPQQDALDELLTGWEHLyyycslRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKP 4845
Cdd:PRK09493   82 VFQQFYLFPHLTALENVMFGPLRV------RGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKP 155
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4846 DILLLDEPSSGMDPcSKRYLWQTIMKEV-REGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQ 4911
Cdd:PRK09493  156 KLMLFDEPTSALDP-ELRHEVLKVMQDLaEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQ 221
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
3841-4061 2.90e-17

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 87.39  E-value: 2.90e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3841 GVTLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQtDLSRVRMELGVC 3920
Cdd:PRK11000    3 SVTLRNVTKAY-GDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMN-DVPPAERGVGMV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3921 PQQDILLDNLTVREHL---LLFASIKapqwtKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTV 3997
Cdd:PRK11000   81 FQSYALYPHLSVAENMsfgLKLAGAK-----KEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVF 155
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 3998 VLDEPTSGVDPCSRHSL-WDIL-LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPFCL 4061
Cdd:PRK11000  156 LLDEPLSNLDAALRVQMrIEISrLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLEL 221
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
3853-4083 2.97e-17

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 85.24  E-value: 2.97e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL-QTDLS---RVRMELGVCPQQDILLD 3928
Cdd:TIGR02769   22 QRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLyQLDRKqrrAFRRDVQLVFQDSPSAV 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3929 N--LTVREhlllfaSIKAP-----QWTKKELHQQVNQTLQDVDL-TQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLD 4000
Cdd:TIGR02769  102 NprMTVRQ------IIGEPlrhltSLDESEQKARIAELLDMVGLrSEDADKLPRQLSGGQLQRINIARALAVKPKLIVLD 175
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4001 EPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRL---RCCGPPFCLKEAYGQGLrltltr 4075
Cdd:TIGR02769  176 EAVSNLDMVLQAVILELLrkLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIveeCDVAQLLSFKHPAGRNL------ 249

                   ....*...
gi 767944871  4076 QPSVLEAH 4083
Cdd:TIGR02769  250 QSAVLPEH 257
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
4688-4917 3.36e-17

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 86.74  E-value: 3.36e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYRRFfqniIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLS---SAG 4764
Cdd:COG1118     3 IEVRNISKRFGSF----TLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVL-----NGRDLFtnlPPR 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4765 TAGVliGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGK 4844
Cdd:COG1118    74 ERRV--GFVFQHYALFPHMTVAENIAFGLRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVE 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4845 PDILLLDEPSSGMDPcskrYLWQTIMKEVRE-----GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI----KN 4915
Cdd:COG1118   152 PEVLLLDEPFGALDA----KVRKELRRWLRRlhdelGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVydrpAT 227

                  ..
gi 767944871 4916 RF 4917
Cdd:COG1118   228 PF 229
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
4706-4902 4.06e-17

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 82.48  E-value: 4.06e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTA---GvlIGYCPQqDALDEL 4782
Cdd:cd03215    15 AVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLD---GKPVTRRSPRDAiraG--IAYVPE-DRKREG 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4783 LtgwehlyyycslrgIPRQCIPEvagDLIRRLHLeahadkpvatySGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSK 4862
Cdd:cd03215    89 L--------------VLDLSVAE---NIALSSLL-----------SGGNQQKVVLARWLARDPRVLILDEPTRGVDVGAK 140
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 767944871 4863 RYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:cd03215   141 AEIYRLIRELADAGKAVLLISSELDELLGLCDRILVMYEG 180
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
4688-4902 4.16e-17

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 82.05  E-value: 4.16e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYRRFFQNIIavQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAG 4767
Cdd:cd03228     1 IEFKNVSFSYPGRPKPVL--KDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILI-----DGVDLRDLDLES 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4768 V--LIGYCPQQDAL------DELLtgwehlyyycslrgiprqcipevagdlirrlhleahadkpvatySGGTKRKLSTAL 4839
Cdd:cd03228    74 LrkNIAYVPQDPFLfsgtirENIL--------------------------------------------SGGQRQRIAIAR 109
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871 4840 ALVGKPDILLLDEPSSGMDPCSKRYLWQTImKEVREGCAAVLTSHSMEECEaLCTRLAIMVNG 4902
Cdd:cd03228   110 ALLRDPPILILDEATSALDPETEALILEAL-RALAKGKTVIVIAHRLSTIR-DADRIIVLDDG 170
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
3857-4051 4.34e-17

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 84.13  E-value: 4.34e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3857 VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT-DLSRVRMELGVCPQQDILLDNlTVREH 3935
Cdd:cd03249    18 ILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDlNLRWLRSQIGLVSQEPVLFDG-TIAEN 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3936 lLLFASIKAPQWTKKELHQQVN-----QTLQDVDLTQHQHKQTRaLSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCS 4010
Cdd:cd03249    97 -IRYGKPDATDEEVEEAAKKANihdfiMSLPDGYDTLVGERGSQ-LSGGQKQRIAIARALLRNPKILLLDEATSALDAES 174
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 767944871 4011 RHSLWDILLKYREGRTIIFTTHHLDEAEAlSDRVAVLQHGR 4051
Cdd:cd03249   175 EKLVQEALDRAMKGRTTIVIAHRLSTIRN-ADLIAVLQNGQ 214
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
3853-4040 4.83e-17

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 83.00  E-value: 4.83e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRME-LGvcpQQDILLDNLT 3931
Cdd:PRK13539   13 GGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAEACHyLG---HRNAMKPALT 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3932 VREHLLLFASIKAPqwtkKELHqqVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLgiAFMGMSRTVV--LDEPTSGVDPC 4009
Cdd:PRK13539   90 VAENLEFWAAFLGG----EELD--IAAALEAVGLAPLAHLPFGYLSAGQKRRVAL--ARLLVSNRPIwiLDEPTAALDAA 161
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 767944871 4010 SRHSLWDILLKYRE-GRTIIFTTHH---LDEAEAL 4040
Cdd:PRK13539  162 AVALFAELIRAHLAqGGIVIAATHIplgLPGAREL 196
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
3849-4052 5.05e-17

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 83.71  E-value: 5.05e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3849 KEY-EG--HKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRM-----ELGVC 3920
Cdd:PRK11629   13 KRYqEGsvQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAelrnqKLGFI 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3921 PQQDILLDNLTVREHL---LLFASIKapqwtKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTV 3997
Cdd:PRK11629   93 YQFHHLLPDFTALENVampLLIGKKK-----PAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLV 167
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 3998 VLDEPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAvLQHGRL 4052
Cdd:PRK11629  168 LADEPTGNLDARNADSIFQLLgeLNRLQGTAFLVVTHDLQLAKRMSRQLE-MRDGRL 223
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
4707-4902 6.43e-17

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 83.28  E-value: 6.43e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4707 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTAGVLIGYcpqqdALDELLTGW 4786
Cdd:TIGR01184    1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILE---GKQITEPGPDRMVVFQNY-----SLLPWLTVR 72
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4787 EHLYYY--CSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRY 4864
Cdd:TIGR01184   73 ENIALAvdRVLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGN 152
                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 767944871  4865 LWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:TIGR01184  153 LQEELMQIWEEhRVTVLMVTHDVDEALLLSDRVVMLTNG 191
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
3853-4057 6.51e-17

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 83.81  E-value: 6.51e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGL-----HPPTSGTIIINGKNL-QTDLSRVRMELGVCPQQDIL 3926
Cdd:PRK14247   14 GQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLielypEARVSGEVYLDGQDIfKMDVIELRRRVQMVFQIPNP 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3927 LDNLTVREHLLLFASIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRA----LSGGLKRKLSLGIAFMGMSRTVVLDEP 4002
Cdd:PRK14247   94 IPNLSIFENVALGLKLNRLVKSKKELQERVRWALEKAQLWDEVKDRLDApagkLSGGQQQRLCIARALAFQPEVLLADEP 173
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4003 TSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGP 4057
Cdd:PRK14247  174 TANLDPENTAKIESLFLELKKDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGP 228
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
3855-4086 6.84e-17

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 84.37  E-value: 6.84e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3855 KAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIING--KNLQTDLSRVRMELGVCPQQDillDN--- 3929
Cdd:PRK13633   23 KLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGldTSDEENLWDIRNKAGMVFQNP---DNqiv 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3930 LTVREHLLLFA--SIKAPQwtkKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSL-GIAFMgMSRTVVLDEPTSGV 4006
Cdd:PRK13633  100 ATIVEEDVAFGpeNLGIPP---EEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIaGILAM-RPECIIFDEPTAML 175
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4007 DPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAeALSDRVAVLQHGRLRCCGPPfclKEAYGQ-------GLRLtltrqP 4077
Cdd:PRK13633  176 DPSGRREVVNTIkeLNKKYGITIILITHYMEEA-VEADRIIVMDSGKVVMEGTP---KEIFKEvemmkkiGLDV-----P 246
                         250
                  ....*....|
gi 767944871 4078 SVLE-AHDLK 4086
Cdd:PRK13633  247 QVTElAYELK 256
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
4692-4913 6.89e-17

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 83.54  E-value: 6.89e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRFfqniIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGVLIG 4771
Cdd:cd03296     7 NVSKRFGDF----VALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILF-----GGEDATDVPVQERNVG 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4772 YCPQQDALDELLTGWEHLYYycSLRGIPRQCIP------EVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKP 4845
Cdd:cd03296    78 FVFQHYALFRHMTVFDNVAF--GLRVKPRSERPpeaeirAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEP 155
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4846 DILLLDEPSSGMDPCSKRYLwQTIMKEVRE--GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:cd03296   156 KVLLLDEPFGALDAKVRKEL-RRWLRRLHDelHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEV 224
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
3860-4058 6.94e-17

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 84.69  E-value: 6.94e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3860 DLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTI------IINGKNlQTDLSRVRMELGVCPQqdilldnltVR 3933
Cdd:PRK13634   25 DVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVtigervITAGKK-NKKLKPLRKKVGIVFQ---------FP 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3934 EHLLLFASIK-----APQ---WTKKELHQQVNQTLQDVDLTQH-QHKQTRALSGGLKRKLSlgIA-FMGMSRTV-VLDEP 4002
Cdd:PRK13634   95 EHQLFEETVEkdicfGPMnfgVSEEDAKQKAREMIELVGLPEElLARSPFELSGGQMRRVA--IAgVLAMEPEVlVLDEP 172
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4003 TSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK13634  173 TAGLDPKGRKEMMEMFykLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTP 230
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
4688-4917 7.09e-17

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 85.90  E-value: 7.09e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYrrffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmGDAV--DLSSA-- 4763
Cdd:COG3839     4 LELENVSKSY----GGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILI----GGRDvtDLPPKdr 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4764 GtagvlIGYCPQQDALdelltgWEHL--Y----YYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLST 4837
Cdd:COG3839    76 N-----IAMVFQSYAL------YPHMtvYeniaFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVAL 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4838 ALALVGKPDILLLDEPSSGMDPCSKrylWQT---IMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:COG3839   145 GRALVREPKVFLLDEPLSNLDAKLR---VEMraeIKRLHRRlGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEEL 221

                  ....*...
gi 767944871 4914 ----KNRF 4917
Cdd:COG3839   222 ydrpANLF 229
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
3839-4058 1.08e-16

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 86.05  E-value: 1.08e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3839 APGVTLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQ-TDLSRVRMEL 3917
Cdd:PRK09536    1 MPMIDVSDLSVEF-GDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEaLSARAASRRV 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3918 GVCPQQDILLDNLTVRE--------HLLLFASikapqWTKKElHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIA 3989
Cdd:PRK09536   80 ASVPQDTSLSFEFDVRQvvemgrtpHRSRFDT-----WTETD-RAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARA 153
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 3990 FMGMSRTVVLDEPTSGVDpcSRHSLWDILLKYR---EGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK09536  154 LAQATPVLLLDEPTASLD--INHQVRTLELVRRlvdDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPP 223
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
4675-4917 1.12e-16

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 85.38  E-value: 1.12e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4675 EKRVFEGRTNGDILVLYNLSKHYrrffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpm 4754
Cdd:PRK09452    2 KKLNKQPSSLSPLVELRGISKSF----DGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIML---- 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4755 gDAVDLSSAGTAGVLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRK 4834
Cdd:PRK09452   74 -DGQDITHVPAENRHVNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQR 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4835 LSTALALVGKPDILLLDEPSSGMDpcskrY-LWQTIMKEVRE-----GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLG 4908
Cdd:PRK09452  153 VAIARAVVNKPKVLLLDESLSALD-----YkLRKQMQNELKAlqrklGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDG 227
                         250
                  ....*....|...
gi 767944871 4909 SPQHI----KNRF 4917
Cdd:PRK09452  228 TPREIyeepKNLF 240
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
4706-4913 1.29e-16

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 83.74  E-value: 1.29e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHaIIRTpmGDAVDLSSAG------TAGVLIgycpqQDAL 4779
Cdd:PRK13636   21 ALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGR-ILFD--GKPIDYSRKGlmklreSVGMVF-----QDPD 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4780 DELLTG--WEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGM 4857
Cdd:PRK13636   93 NQLFSAsvYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGL 172
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4858 DPCSKrylwQTIMKEVRE-----GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:PRK13636  173 DPMGV----SEIMKLLVEmqkelGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEV 229
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
3849-4058 1.36e-16

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 85.14  E-value: 1.36e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3849 KEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKnlqtDLSRVRM---ELGVCPQQDI 3925
Cdd:PRK10851    9 KKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGT----DVSRLHArdrKVGFVFQHYA 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3926 LLDNLTVREHLLLFASI----KAPqwTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDE 4001
Cdd:PRK10851   85 LFRHMTVFDNIAFGLTVlprrERP--NAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLDE 162
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871 4002 PTSGVDPCSRHSLWDIL------LKYregrTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK10851  163 PFGALDAQVRKELRRWLrqlheeLKF----TSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTP 221
cbiO PRK13646
energy-coupling factor transporter ATPase;
3851-4072 1.55e-16

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 83.68  E-value: 1.55e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3851 YEgHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIING-----KNLQTDLSRVRMELGVC---PQ 3922
Cdd:PRK13646   18 YE-HQAI-HDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDitithKTKDKYIRPVRKRIGMVfqfPE 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3923 QDILLDNLtvrEHLLLFASiKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTR-ALSGGLKRKLSLgIAFMGMS-RTVVLD 4000
Cdd:PRK13646   96 SQLFEDTV---EREIIFGP-KNFKMNLDEVKNYAHRLLMDLGFSRDVMSQSPfQMSGGQMRKIAI-VSILAMNpDIIVLD 170
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 4001 EPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPfclKEAYGQGLRLT 4072
Cdd:PRK13646  171 EPTAGLDPQSKRQVMRLLksLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSP---KELFKDKKKLA 241
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
4703-4902 1.64e-16

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 82.34  E-value: 1.64e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4703 NIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGT-----AGvlIGYCPQQD 4777
Cdd:COG0410    15 GIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRF-----DGEDITGLPPhriarLG--IGYVPEGR 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4778 ALDELLTGWEHL---YYYCSLRGIPRQCIPEVAG---DLIRRLHLEAhadkpvATYSGGTKRKLSTALALVGKPDILLLD 4851
Cdd:COG0410    88 RIFPSLTVEENLllgAYARRDRAEVRADLERVYElfpRLKERRRQRA------GTLSGGEQQMLAIGRALMSRPKLLLLD 161
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 767944871 4852 EPSSGMDPcskRY---LWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:COG0410   162 EPSLGLAP---LIveeIFEIIRRLNREGVTILLVEQNARFALEIADRAYVLERG 212
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
4706-4902 1.74e-16

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 82.37  E-value: 1.74e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpMGDAVDLSSAGTAGVL------IGYCPQQDAL 4779
Cdd:PRK11124   17 ALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNI---AGNHFDFSKTPSDKAIrelrrnVGMVFQQYNL 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4780 delltgWEHLYYY-------CSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDE 4852
Cdd:PRK11124   94 ------WPHLTVQqnlieapCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDE 167
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 767944871 4853 PSSGMDPcskRYLWQ--TIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:PRK11124  168 PTAALDP---EITAQivSIIRELAEtGITQVIVTHEVEVARKTASRVVYMENG 217
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
3841-4052 1.89e-16

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 82.37  E-value: 1.89e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3841 GVTLVSVTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGK--NLQTDLS-----RV 3913
Cdd:COG4161     2 SIQLKNINCFYGSHQAL-FDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHqfDFSQKPSekairLL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3914 RMELGVCPQQDILLDNLTVREHLllfasIKAPQW----TKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIA 3989
Cdd:COG4161    81 RQKVGMVFQQYNLWPHLTVMENL-----IEAPCKvlglSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARA 155
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 3990 FMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYRE-GRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:COG4161   156 LMMEPQVLLFDEPTAALDPEITAQVVEIIRELSQtGITQVIVTHEVEFARKVASQVVYMEKGRI 219
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
3839-4052 1.95e-16

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 86.23  E-value: 1.95e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3839 APGVTLVSV----TKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLS-RV 3913
Cdd:COG3845   252 EPGEVVLEVenlsVRDDRGVPAL-KDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDI-TGLSpRE 329
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3914 RMELGVC-----PQQDILLDNLTVREHLLLfASIKAPQWTK------KELHQQVNQTLQDVDL-TQHQHKQTRALSGGLK 3981
Cdd:COG3845   330 RRRLGVAyipedRLGRGLVPDMSVAENLIL-GRYRRPPFSRggfldrKAIRAFAEELIEEFDVrTPGPDTPARSLSGGNQ 408
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 3982 RKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:COG3845   409 QKVILARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRdAGAAVLLISEDLDEILALSDRIAVMYEGRI 480
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
4706-4924 2.07e-16

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 82.82  E-value: 2.07e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAG------TAGVLIgycpqQDAL 4779
Cdd:PRK13639   17 ALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIK---GEPIKYDKKSllevrkTVGIVF-----QNPD 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4780 DELL--TGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGM 4857
Cdd:PRK13639   89 DQLFapTVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGL 168
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4858 DPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIknrFGDGYTVK 4924
Cdd:PRK13639  169 DPMGASQIMKLLYDLNKEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEV---FSDIETIR 232
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
3829-4057 2.60e-16

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 82.84  E-value: 2.60e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3829 QNREGELEGSAPGVTLVSVTKEYEGhKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSG-----TIIING 3903
Cdd:PRK14271    9 QSGAADVDAAAPAMAAVNLTLGFAG-KTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGyrysgDVLLGG 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3904 KNL--QTDLSRVRMELGVCPQQD-----ILLDNLT--VREHLLL----FASIKAPQWTKKELHQQVNQTLQDVDLTqhqh 3970
Cdd:PRK14271   88 RSIfnYRDVLEFRRRVGMLFQRPnpfpmSIMDNVLagVRAHKLVprkeFRGVAQARLTEVGLWDAVKDRLSDSPFR---- 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3971 kqtraLSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEALSDRVAVLQHG 4050
Cdd:PRK14271  164 -----LSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADRLTVIIVTHNLAQAARISDRAALFFDG 238

                  ....*..
gi 767944871 4051 RLRCCGP 4057
Cdd:PRK14271  239 RLVEEGP 245
cbiO PRK13637
energy-coupling factor transporter ATPase;
4706-4910 3.64e-16

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 82.40  E-value: 3.64e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGT--------AGVLIGYcPQQD 4777
Cdd:PRK13637   22 ALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIII-----DGVDITDKKVklsdirkkVGLVFQY-PEYQ 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4778 ALDEllTGWEHLYYYCSLRGIPRQCIPEVAGDLIR--RLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSS 4855
Cdd:PRK13637   96 LFEE--TIEKDIAFGPINLGLSEEEIENRVKRAMNivGLDYEDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTA 173
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4856 GMDPCSKrylwQTIMKEVRE-----GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSP 4910
Cdd:PRK13637  174 GLDPKGR----DEILNKIKElhkeyNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTP 229
cbiO PRK13650
energy-coupling factor transporter ATPase;
3858-4071 4.01e-16

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 82.09  E-value: 4.01e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3858 VQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTD-LSRVRMELGVCPQQDillDN----LTV 3932
Cdd:PRK13650   23 LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEEnVWDIRHKIGMVFQNP---DNqfvgATV 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3933 REHLLLFASIKApqWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRH 4012
Cdd:PRK13650  100 EDDVAFGLENKG--IPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRL 177
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4013 SLWDILLKYRE--GRTIIFTTHHLDEAeALSDRVAVLQHGRLRCCGPPfclKEAYGQGLRL 4071
Cdd:PRK13650  178 ELIKTIKGIRDdyQMTVISITHDLDEV-ALSDRVLVMKNGQVESTSTP---RELFSRGNDL 234
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
4668-4884 4.49e-16

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 85.66  E-value: 4.49e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4668 DTDVEKEE--KRVFEGRTNGDIlVLYNLSKHYRRffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTS 4745
Cdd:COG2274   453 DLPPEREEgrSKLSLPRLKGDI-ELENVSFRYPG--DSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTS 529
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4746 GHAIIrtpmgDAVDLSSAGTAGV--LIGYCPQQdalDELLTGwehlyyycSLR--------GIP----RQCIpEVAG--D 4809
Cdd:COG2274   530 GRILI-----DGIDLRQIDPASLrrQIGVVLQD---VFLFSG--------TIRenitlgdpDATdeeiIEAA-RLAGlhD 592
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4810 LIRRL------HLEAHAdkpvATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTImKEVREGCAAVLTS 4883
Cdd:COG2274   593 FIEALpmgydtVVGEGG----SNLSGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENL-RRLLKGRTVIIIA 667

                  .
gi 767944871 4884 H 4884
Cdd:COG2274   668 H 668
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
4706-4913 4.51e-16

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 81.99  E-value: 4.51e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGhaIIRTpmgDAVDLSSAGTAGV--LIGYCPQQ------- 4776
Cdd:PRK13635   22 ALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAG--TITV---GGMVLSEETVWDVrrQVGMVFQNpdnqfvg 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4777 -DALDELLTGWEHlyyycslRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSS 4855
Cdd:PRK13635   97 aTVQDDVAFGLEN-------IGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATS 169
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 4856 GMDPCSKRYLWQTIMKEVREGCAAVLT-SHSMEECeALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:PRK13635  170 MLDPRGRREVLETVRQLKEQKGITVLSiTHDLDEA-AQADRVIVMNKGEILEEGTPEEI 227
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
3846-4052 5.41e-16

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 80.83  E-value: 5.41e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3846 SVTKEYEGHKAVVqDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIIngKNLQTDLSR---------VRME 3916
Cdd:PRK11124    7 GINCFYGAHQALF-DITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNI--AGNHFDFSKtpsdkaireLRRN 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3917 LGVCPQQDILLDNLTVREHLllfasIKAP----QWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMg 3992
Cdd:PRK11124   84 VGMVFQQYNLWPHLTVQQNL-----IEAPcrvlGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALM- 157
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 3993 MSRTVVL-DEPTSGVDPCSRHSLWDILLKYRE-GRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:PRK11124  158 MEPQVLLfDEPTAALDPEITAQIVSIIRELAEtGITQVIVTHEVEVARKTASRVVYMENGHI 219
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
3827-4052 6.72e-16

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 85.01  E-value: 6.72e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3827 SLQNREGElegsapgVTLVSVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL 3906
Cdd:PRK13657  327 DLGRVKGA-------VEFDDVSFSYDNSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDI 399
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3907 QT-DLSRVRMELGVCpQQDILLDNLTVREHLllfaSIKAPQWTKKELHQ--QVNQTLqDVDLTQHQHKQT------RALS 3977
Cdd:PRK13657  400 RTvTRASLRRNIAVV-FQDAGLFNRSIEDNI----RVGRPDATDEEMRAaaERAQAH-DFIERKPDGYDTvvgergRQLS 473
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 3978 GGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDE-AEAlsDRVAVLQHGRL 4052
Cdd:PRK13657  474 GGERQRLAIARALLKDPPILILDEATSALDVETEAKVKAALDELMKGRTTFIIAHRLSTvRNA--DRILVFDNGRV 547
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
3857-4051 7.00e-16

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 79.44  E-value: 7.00e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3857 VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKnlqtdlsrvrmeLGVCPQQDILLdNLTVREHl 3936
Cdd:cd03250    20 TLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS------------IAYVSQEPWIQ-NGTIREN- 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3937 LLFASIKAPQWTKKELH----QQVNQTLQDVDLTQHQHKQTrALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRH 4012
Cdd:cd03250    86 ILFGKPFDEERYEKVIKacalEPDLEILPDGDLTEIGEKGI-NLSGGQKQRISLARAVYSDADIYLLDDPLSAVDAHVGR 164
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 767944871 4013 SLWD--ILLKYREGRTIIFTTHHLdeaEALS--DRVAVLQHGR 4051
Cdd:cd03250   165 HIFEncILGLLLNNKTRILVTHQL---QLLPhaDQIVVLDNGR 204
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
3851-4052 7.55e-16

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 80.85  E-value: 7.55e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3851 YEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHP--P---TSGTIIINGKNL---QTDLSRVRMELGVCPQ 3922
Cdd:COG1117    20 YYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMNDliPgarVEGEILLDGEDIydpDVDVVELRRRVGMVFQ 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3923 QDILL-----DNLT--VREHlllfaSIKapqwTKKELHQQVNQTLQDVDL---TQHQ-HKQTRALSGGLKRKLSlgIAfm 3991
Cdd:COG1117   100 KPNPFpksiyDNVAygLRLH-----GIK----SKSELDEIVEESLRKAALwdeVKDRlKKSALGLSGGQQQRLC--IA-- 166
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 3992 gmsRT------VVL-DEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:COG1117   167 ---RAlavepeVLLmDEPTSALDPISTAKIEELILELKKDYTIVIVTHNMQQAARVSDYTAFFYLGEL 231
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
4707-4902 1.02e-15

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 78.03  E-value: 1.02e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTA--GVLIGYCPQQdalDELLT 4784
Cdd:cd03246    18 LRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRL-----DGADISQWDPNelGDHVGYLPQD---DELFS 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4785 GwehlyyycSLRgiprqcipevagDLIrrlhleahadkpvatYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRY 4864
Cdd:cd03246    90 G--------SIA------------ENI---------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERA 134
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 767944871 4865 LWQTI--MKEvrEGCAAVLTSHSMEECEAlCTRLAIMVNG 4902
Cdd:cd03246   135 LNQAIaaLKA--AGATRIVIAHRPETLAS-ADRILVLEDG 171
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
3843-4037 1.04e-15

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 80.51  E-value: 1.04e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3843 TLVSVTKEYEGhKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSrvrmELGVCPQ 3922
Cdd:PRK11248    3 QISHLYADYGG-KPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGA----ERGVVFQ 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3923 QDILLDNLTVREHL---LLFASIkapqwTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVL 3999
Cdd:PRK11248   78 NEGLLPWRNVQDNVafgLQLAGV-----EKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLL 152
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 767944871 4000 DEPTSGVDPCSRHSLWDILLK--YREGRTIIFTTHHLDEA 4037
Cdd:PRK11248  153 DEPFGALDAFTREQMQTLLLKlwQETGKQVLLITHDIEEA 192
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
3869-4032 1.18e-15

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 78.44  E-value: 1.18e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3869 QITALLGTNGAGKTTIISML-----TGLhppTSGTIIINGKNLQTDLSRvrmELGVCPQQDILLDNLTVREHLLLFASIk 3943
Cdd:cd03232    34 TLTALMGESGAGKTTLLDVLagrktAGV---ITGEILINGRPLDKNFQR---STGYVEQQDVHSPNLTVREALRFSALL- 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3944 apqwtkkelhqqvnqtlqdvdltqhqhkqtRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKY-R 4022
Cdd:cd03232   107 ------------------------------RGLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQAAYNIVRFLKKLaD 156
                         170
                  ....*....|
gi 767944871 4023 EGRTIIFTTH 4032
Cdd:cd03232   157 SGQAILCTIH 166
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
3855-4068 1.34e-15

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 78.72  E-value: 1.34e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3855 KAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGlHP---PTSGTIIINGKNLqTDLS---RVRMELGVCPQQDILLD 3928
Cdd:cd03217    13 KEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMG-HPkyeVTEGEILFKGEDI-TDLPpeeRARLGIFLAFQYPPEIP 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3929 NLTVREHLllfasikapqwtkkelhQQVNQTlqdvdltqhqhkqtraLSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDP 4008
Cdd:cd03217    91 GVKNADFL-----------------RYVNEG----------------FSGGEKKRNEILQLLLLEPDLAILDEPDSGLDI 137
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4009 CSRHSLWDILLKYR-EGRTIIFTTHHLDEAEAL-SDRVAVLQHGRLRCCGPPFCLKEAYGQG 4068
Cdd:cd03217   138 DALRLVAEVINKLReEGKSVLIITHYQRLLDYIkPDRVHVLYDGRIVKSGDKELALEIEKKG 199
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
4706-4903 1.45e-15

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 80.31  E-value: 1.45e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGH-AIIRTPMGDAVDLSsagtagvLIGYCPQQDALD---- 4780
Cdd:PRK15056   22 ALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKiSILGQPTRQALQKN-------LVAYVPQSEEVDwsfp 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4781 ------ELLTGWEHLYYycsLRgIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPS 4854
Cdd:PRK15056   95 vlvedvVMMGRYGHMGW---LR-RAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPF 170
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 767944871 4855 SGMDPCSKRYLWqTIMKEVR-EGCAAVLTSHSMEECEALCTrLAIMVNGS 4903
Cdd:PRK15056  171 TGVDVKTEARII-SLLRELRdEGKTMLVSTHNLGSVTEFCD-YTVMVKGT 218
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
3855-4056 1.56e-15

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 84.00  E-value: 1.56e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3855 KAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL-QTDLSRVRMELGVCpQQDILLDNLTVR 3933
Cdd:TIGR00958  494 VPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLvQYDHHYLHRQVALV-GQEPVLFSGSVR 572
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3934 EHL---LLFASIKAPQWTKKE--LHQQVNQTLQDVDLTQHQHKQTraLSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDP 4008
Cdd:TIGR00958  573 ENIaygLTDTPDEEIMAAAKAanAHDFIMEFPNGYDTEVGEKGSQ--LSGGQKQRIAIARALVRKPRVLILDEATSALDA 650
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 767944871  4009 CSRHSLWDilLKYREGRTIIFTTHHLDEAEAlSDRVAVLQHGRLRCCG 4056
Cdd:TIGR00958  651 ECEQLLQE--SRSRASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMG 695
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
3849-4058 1.62e-15

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 80.01  E-value: 1.62e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3849 KEYEGHKaVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL--------------QTDLSRVR 3914
Cdd:PRK10619   13 KRYGEHE-VLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTInlvrdkdgqlkvadKNQLRLLR 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3915 MELGVCPQQDILLDNLTVREHLLLfASIKAPQWTKKELHQQVNQTLQDVDLTQH-QHKQTRALSGGLKRKLSLGIAFMGM 3993
Cdd:PRK10619   92 TRLTMVFQHFNLWSHMTVLENVME-APIQVLGLSKQEARERAVKYLAKVGIDERaQGKYPVHLSGGQQQRVSIARALAME 170
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 3994 SRTVVLDEPTSGVDPCSRHSLWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK10619  171 PEVLLFDEPTSALDPELVGEVLRIMQQLaEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAP 236
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
3838-4056 1.94e-15

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 79.71  E-value: 1.94e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3838 SAPGVTLVSVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL-------QTDL 3910
Cdd:PRK14246    6 SAEDVFNISRLYLYINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLyfgkdifQIDA 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3911 SRVRMELGVCPQQDILLDNLTVREHL---LLFASIKapqwTKKELHQQVNQTLQDVDLTQHQHKQTRA----LSGGLKRK 3983
Cdd:PRK14246   86 IKLRKEVGMVFQQPNPFPHLSIYDNIaypLKSHGIK----EKREIKKIVEECLRKVGLWKEVYDRLNSpasqLSGGQQQR 161
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871 3984 LSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCG 4056
Cdd:PRK14246  162 LTIARALALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWG 234
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
4690-4923 2.11e-15

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 79.71  E-value: 2.11e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4690 LYNLSKHYRrFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLN-------------GEVsLTSGHAIIRTpmgD 4756
Cdd:PRK14246   10 VFNISRLYL-YINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNrlieiydskikvdGKV-LYFGKDIFQI---D 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4757 AVDLSSAgtagvlIGYCPQQDALDELLTGWEHLYYYCSLRGIP-RQCIPEVAGDLIRRLHL--EAH--ADKPVATYSGGT 4831
Cdd:PRK14246   85 AIKLRKE------VGMVFQQPNPFPHLSIYDNIAYPLKSHGIKeKREIKKIVEECLRKVGLwkEVYdrLNSPASQLSGGQ 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4832 KRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLwQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQ 4911
Cdd:PRK14246  159 QQRLTIARALALKPKVLLMDEPTSMIDIVNSQAI-EKLITELKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSN 237
                         250
                  ....*....|....*.
gi 767944871 4912 HI----KNRFGDGYTV 4923
Cdd:PRK14246  238 EIftspKNELTEKYVI 253
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
3842-4052 2.29e-15

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 79.34  E-value: 2.29e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINgknlQTDLSRVRMELGVCP 3921
Cdd:PRK11247   13 LLLNAVSKRY-GERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAG----TAPLAEAREDTRLMF 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QQDILL------DN--LTVREHlllfasikapqWTKKELhqqvnQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGM 3993
Cdd:PRK11247   88 QDARLLpwkkviDNvgLGLKGQ-----------WRDAAL-----QALAAVGLADRANEWPAALSGGQKQRVALARALIHR 151
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 3994 SRTVVLDEPTSGVDPCSR-------HSLWDillkyREGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:PRK11247  152 PGLLLLDEPLGALDALTRiemqdliESLWQ-----QHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
4709-4916 2.34e-15

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 81.31  E-value: 2.34e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4709 DISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGVL------IGYCPQQDALDEL 4782
Cdd:TIGR02142   15 DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVL-----NGRTLFDSRKGIFLppekrrIGYVFQEARLFPH 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4783 LTGWEHLYY-YCSLRGIPRQCIPEvagDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCS 4861
Cdd:TIGR02142   90 LSVRGNLRYgMKRARPSERRISFE---RVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPR 166
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871  4862 KR----YLwQTIMKEVREGCaaVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKNR 4916
Cdd:TIGR02142  167 KYeilpYL-ERLHAEFGIPI--LYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWAS 222
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
4702-4902 3.10e-15

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 78.02  E-value: 3.10e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4702 QNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAgVL---IGYCPQQDA 4778
Cdd:cd03245    15 QEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLL-----DGTDIRQLDPA-DLrrnIGYVPQDVT 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4779 LdelltgwehlyYYCSLR-----GIP---RQCIPEVA-----GDLIRRlhleaHA---DKPV----ATYSGGTKRKLSTA 4838
Cdd:cd03245    89 L-----------FYGTLRdnitlGAPladDERILRAAelagvTDFVNK-----HPnglDLQIgergRGLSGGQRQAVALA 152
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 4839 LALVGKPDILLLDEPSSGMDPCSKRYLWQTiMKEVREGCAAVLTSH--SMEEceaLCTRLAIMVNG 4902
Cdd:cd03245   153 RALLNDPPILLLDEPTSAMDMNSEERLKER-LRQLLGDKTLIIITHrpSLLD---LVDRIIVMDSG 214
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
4692-4915 3.89e-15

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 78.88  E-value: 3.89e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRFFQNiiAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGV--L 4769
Cdd:PRK13632   12 NVSFSYPNSENN--ALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKI-----DGITISKENLKEIrkK 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4770 IGYCPQQ--------DALDELLTGWEHlyyycslRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALAL 4841
Cdd:PRK13632   85 IGIIFQNpdnqfigaTVEDDIAFGLEN-------KKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVL 157
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 4842 VGKPDILLLDEPSSGMDPCSKRYLWQtIMKEVREGCAAVLTS--HSMEECeALCTRLAIMVNGSFKCLGSPQHIKN 4915
Cdd:PRK13632  158 ALNPEIIIFDESTSMLDPKGKREIKK-IMVDLRKTRKKTLISitHDMDEA-ILADKVIVFSEGKLIAQGKPKEILN 231
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
4702-4913 4.82e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 78.98  E-value: 4.82e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4702 QNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAG-------TAGVLIgycp 4774
Cdd:PRK13633   21 TEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYV-----DGLDTSDEEnlwdirnKAGMVF---- 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4775 qQDALDELLT---------GWEHLyyycslrGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKP 4845
Cdd:PRK13633   92 -QNPDNQIVAtiveedvafGPENL-------GIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRP 163
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 4846 DILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECeALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:PRK13633  164 ECIIFDEPTAMLDPSGRREVVNTIKELNKKyGITIILITHYMEEA-VEADRIIVMDSGKVVMEGTPKEI 231
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
4706-4902 5.02e-15

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 81.60  E-value: 5.02e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTA---GvlIGYCP---QQDAL 4779
Cdd:COG1129   267 VVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLD---GKPVRIRSPRDAiraG--IAYVPedrKGEGL 341
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4780 DELLTGWE-----HLYYYCSLRGIPRQCIPEVAGDLIRRLHLEA-HADKPVATYSGGTKRKLSTALALVGKPDILLLDEP 4853
Cdd:COG1129   342 VLDLSIREnitlaSLDRLSRGGLLDRRRERALAEEYIKRLRIKTpSPEQPVGNLSGGNQQKVVLAKWLATDPKVLILDEP 421
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 767944871 4854 SSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:COG1129   422 TRGIDVGAKAEIYRLIRELAAEGKAVIVISSELPELLGLSDRILVMREG 470
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
3853-4058 5.75e-15

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 78.49  E-value: 5.75e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSR-VRMELGVCPQQDILLDNLT 3931
Cdd:PRK10253   18 GKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKeVARRIGLLAQNATTPGDIT 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3932 VREhllLFASIKAP------QWtKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSG 4005
Cdd:PRK10253   98 VQE---LVARGRYPhqplftRW-RKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTW 173
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4006 VDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK10253  174 LDISHQIDLLELLseLNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAP 228
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
3842-4058 6.23e-15

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 77.85  E-value: 6.23e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKnlqtdlsrvrMELGVCP 3921
Cdd:PRK09544    5 VSLENVSVSF-GQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGK----------LRIGYVP 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QQdILLDN---LTVREHLLLFASIKA----PQWTKKELHQQVNQTLQDvdltqhqhkqtraLSGGLKRKLSLGIAFMGMS 3994
Cdd:PRK09544   74 QK-LYLDTtlpLTVNRFLRLRPGTKKedilPALKRVQAGHLIDAPMQK-------------LSGGETQRVLLARALLNRP 139
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 3995 RTVVLDEPTSGVDPCSRHSLWDILLKYRE--GRTIIFTTHHLDEAEALSDRVAVLQHgRLRCCGPP 4058
Cdd:PRK09544  140 QLLVLDEPTQGVDVNGQVALYDLIDQLRRelDCAVLMVSHDLHLVMAKTDEVLCLNH-HICCSGTP 204
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
4707-4913 6.70e-15

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 80.27  E-value: 6.70e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTAGVLIGYCPQQDALDELLTGW 4786
Cdd:PRK09536   19 LDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVA---GDDVEALSARAASRRVASVPQDTSLSFEFDVR 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4787 E--------HLYYYCSLRGIPRQCIPEVagdlIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMD 4858
Cdd:PRK09536   96 QvvemgrtpHRSRFDTWTETDRAAVERA----MERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTASLD 171
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4859 PCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:PRK09536  172 INHQVRTLELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADV 226
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
3847-4053 6.91e-15

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 81.26  E-value: 6.91e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGknlqtdlsrvRMELGVCPQQDIL 3926
Cdd:COG0488     4 LSKSF-GGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPK----------GLRIGYLPQEPPL 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3927 LDNLTVREHLL-----------------------------------LFASIKApqWtkkELHQQVNQTLQDVDLTQHQH- 3970
Cdd:COG0488    73 DDDLTVLDTVLdgdaelraleaeleeleaklaepdedlerlaelqeEFEALGG--W---EAEARAEEILSGLGFPEEDLd 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3971 KQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYReGrTIIFTTH--H-LDeaeALSDRVAVL 4047
Cdd:COG0488   148 RPVSELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLESIEWLEEFLKNYP-G-TVLVVSHdrYfLD---RVATRILEL 222

                  ....*.
gi 767944871 4048 QHGRLR 4053
Cdd:COG0488   223 DRGKLT 228
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
3844-4052 8.57e-15

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 81.69  E-value: 8.57e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3844 LVSVTKEY---EGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT----DLSRVRME 3916
Cdd:PRK10535    7 LKDIRRSYpsgEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATldadALAQLRRE 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3917 -LGVCPQQDILLDNLTVREHL---LLFASIKapqwtKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMG 3992
Cdd:PRK10535   87 hFGFIFQRYHLLSHLTAAQNVevpAVYAGLE-----RKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMN 161
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 3993 MSRTVVLDEPTSGVDPCSRHSLWDILLKYRE-GRTIIFTTHHLDEAeALSDRVAVLQHGRL 4052
Cdd:PRK10535  162 GGQVILADEPTGALDSHSGEEVMAILHQLRDrGHTVIIVTHDPQVA-AQAERVIEIRDGEI 221
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
3847-4052 9.07e-15

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 78.59  E-value: 9.07e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEG----HKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVcpq 3922
Cdd:PRK13651    8 IVKIFNKklptELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWIFKDEKNKKKTKEKEKVL--- 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3923 QDILLDNLTVR-------------------EHLLLFASIK-----APQ---WTKKELHQQVNQTLQDVDLTQ-HQHKQTR 3974
Cdd:PRK13651   85 EKLVIQKTRFKkikkikeirrrvgvvfqfaEYQLFEQTIEkdiifGPVsmgVSKEEAKKRAAKYIELVGLDEsYLQRSPF 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3975 ALSGGLKRKLSL-GIAFMGmSRTVVLDEPTSGVDPCSRHSLWDILLK-YREGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:PRK13651  165 ELSGGQKRRVALaGILAME-PDFLVFDEPTAGLDPQGVKEILEIFDNlNKQGKTIILVTHDLDNVLEWTKRTIFFKDGKI 243
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
3844-4050 1.24e-14

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 80.43  E-value: 1.24e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3844 LVSVTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRME--LGVCP 3921
Cdd:PRK10762    7 LKGIDKAFPGVKAL-SGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFNGPKSSQEagIGIIH 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QQDILLDNLTVREHLLL-------FASIkapQWtkKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMS 3994
Cdd:PRK10762   86 QELNLIPQLTIAENIFLgrefvnrFGRI---DW--KKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFES 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 3995 RTVVLDEPTSGVDPCSRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVLQHG 4050
Cdd:PRK10762  161 KVIIMDEPTDALTDTETESLFRVIRELKsQGRGIVYISHRLKEIFEICDDVTVFRDG 217
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
4697-4887 1.32e-14

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 75.91  E-value: 1.32e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4697 YRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSS-AGTAGVL----IG 4771
Cdd:cd03292     7 TKTYPNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRV-----NGQDVSDlRGRAIPYlrrkIG 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4772 YCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLD 4851
Cdd:cd03292    82 VVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIAD 161
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 767944871 4852 EPSSGMDPcskRYLWQ--TIMKEVRE-GCAAVLTSHSME 4887
Cdd:cd03292   162 EPTGNLDP---DTTWEimNLLKKINKaGTTVVVATHAKE 197
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
3842-4057 1.38e-14

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 77.10  E-value: 1.38e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHkAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTI------IINGKNL---QTDLSR 3912
Cdd:PRK11264    4 IEVKNLVKKFHGQ-TVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIrvgditIDTARSLsqqKGLIRQ 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3913 VRMELGVCPQQDILLDNLTVREHLllfasIKAPQWTKKELHQQV----NQTLQDVDLTQHQHKQTRALSGGLKRKLSLGI 3988
Cdd:PRK11264   83 LRQHVGFVFQNFNLFPHRTVLENI-----IEGPVIVKGEPKEEAtaraRELLAKVGLAGKETSYPRRLSGGQQQRVAIAR 157
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 3989 AfMGMSRTVVL-DEPTSGVDPcsrHSLWDILLKYR----EGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGP 4057
Cdd:PRK11264  158 A-LAMRPEVILfDEPTSALDP---ELVGEVLNTIRqlaqEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGP 227
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
4687-4902 1.51e-14

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 76.46  E-value: 1.51e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYRRffqnIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTA 4766
Cdd:PRK11614    5 MLSFDKVSAHYGK----IQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVF-----DGKDITDWQTA 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4767 GVL---IGYCPQQDALDELLTGWEHLYY--YCSLRGIPRQCIPEVAgDLIRRLHLEAHadKPVATYSGGTKRKLSTALAL 4841
Cdd:PRK11614   76 KIMreaVAIVPEGRRVFSRMTVEENLAMggFFAERDQFQERIKWVY-ELFPRLHERRI--QRAGTMSGGEQQMLAIGRAL 152
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4842 VGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:PRK11614  153 MSQPRLLLLDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENG 213
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
3869-4050 1.76e-14

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 81.31  E-value: 1.76e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3869 QITALLGTNGAGKTTIISML-----TGLhpPTSGTIIINGKNLQTDLSRVrmeLGVCPQQDILLDNLTVREHLLLFASIK 3943
Cdd:TIGR00956  790 TLTALMGASGAGKTTLLNVLaervtTGV--ITGGDRLVNGRPLDSSFQRS---IGYVQQQDLHLPTSTVRESLRFSAYLR 864
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3944 APQ-WTKKELHQQVNQTLQDVDLTQHQHkqtrALSG----GL----KRKLSLGIAFMGMSRTVV-LDEPTSGVDpcSRhS 4013
Cdd:TIGR00956  865 QPKsVSKSEKMEYVEEVIKLLEMESYAD----AVVGvpgeGLnveqRKRLTIGVELVAKPKLLLfLDEPTSGLD--SQ-T 937
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 767944871  4014 LWDILLKYRE----GRTIIFTTHH-----LDEAealsDRVAVLQHG 4050
Cdd:TIGR00956  938 AWSICKLMRKladhGQAILCTIHQpsailFEEF----DRLLLLQKG 979
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
3853-4070 1.80e-14

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 77.03  E-value: 1.80e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLSRVRME-------------LG- 3918
Cdd:PRK10419   23 QHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPL-AKLNRAQRKafrrdiqmvfqdsISa 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3919 VCPQQDIlldNLTVRE---HLLlfasikapQWTKKELHQQVNQTLQDVDLT-QHQHKQTRALSGGLKRKLSLGIAFMGMS 3994
Cdd:PRK10419  102 VNPRKTV---REIIREplrHLL--------SLDKAERLARASEMLRAVDLDdSVLDKRPPQLSGGQLQRVCLARALAVEP 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3995 RTVVLDEPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRL---RCCGPPFCLKEAYGQGL 4069
Cdd:PRK10419  171 KLLILDEAVSNLDLVLQAGVIRLLkkLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIvetQPVGDKLTFSSPAGRVL 250

                  .
gi 767944871 4070 R 4070
Cdd:PRK10419  251 Q 251
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
3928-4052 2.09e-14

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 78.24  E-value: 2.09e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3928 DNLTVREHLLLFAsiKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVD 4007
Cdd:NF000106   99 ESFSGRENLYMIG--R*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLD 176
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 767944871 4008 PCSRHSLWD-ILLKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:NF000106  177 PRTRNEVWDeVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRV 222
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
3840-4053 2.13e-14

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 76.61  E-value: 2.13e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3840 PGVTLVSVTKEYEGHKaVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTS-----GTIIINGKNL---QTDLS 3911
Cdd:PRK14258    6 PAIKVNNLSFYYDTQK-ILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESevrveGRVEFFNQNIyerRVNLN 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3912 RVRMELG-VCPQQDI----LLDNLTVrehlllfaSIKAPQWTKK-ELHQQVNQTLQDVDL---TQHQ-HKQTRALSGGLK 3981
Cdd:PRK14258   85 RLRRQVSmVHPKPNLfpmsVYDNVAY--------GVKIVGWRPKlEIDDIVESALKDADLwdeIKHKiHKSALDLSGGQQ 156
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 3982 RKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLR 4053
Cdd:PRK14258  157 QRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIqsLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGNENR 230
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
4692-4886 2.15e-14

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 75.26  E-value: 2.15e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRFfqniIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTAGVL-- 4769
Cdd:cd03262     5 NLHKSFGDF----HVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIID---GLKLTDDKKNINELRqk 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4770 IGYCPQQDALDELLTGWEHlyyyCSL-----RGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGK 4844
Cdd:cd03262    78 VGMVFQQFNLFPHLTVLEN----ITLapikvKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMN 153
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 767944871 4845 PDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSM 4886
Cdd:cd03262   154 PKVMLFDEPTSALDPELVGEVLDVMKDLAEEGMTMVVVTHEM 195
cbiO PRK13644
energy-coupling factor transporter ATPase;
4706-4913 2.25e-14

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 76.95  E-value: 2.25e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPmgDAVDLSSAGTAGVLIGYCPQ--------QD 4777
Cdd:PRK13644   17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGI--DTGDFSKLQGIRKLVGIVFQnpetqfvgRT 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4778 ALDELLTGWEHLyyycslrgiprqCIPEVAgdlIRRL--------HLEAHADKPVATYSGGTKRKLSTALALVGKPDILL 4849
Cdd:PRK13644   95 VEEDLAFGPENL------------CLPPIE---IRKRvdralaeiGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLI 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 4850 LDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEAlCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:PRK13644  160 FDEVTSMLDPDSGIAVLERIKKLHEKGKTIVYITHNLEELHD-ADRIIVMDRGKIVLEGEPENV 222
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
3853-4042 2.40e-14

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 76.73  E-value: 2.40e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTdLSR-----VRMELGVCPQQDILL 3927
Cdd:PRK11831   18 GNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPA-MSRsrlytVRKRMSMLFQSGALF 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3928 DNLTV--------REHLLLFASIkapqwtkkeLHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVL 3999
Cdd:PRK11831   97 TDMNVfdnvayplREHTQLPAPL---------LHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMF 167
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 767944871 4000 DEPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSD 4042
Cdd:PRK11831  168 DEPFVGQDPITMGVLVKLIseLNSALGVTCVVVSHDVPEVLSIAD 212
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
4699-4913 2.49e-14

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 78.20  E-value: 2.49e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4699 RFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHaiIRTpmgDAVDLSSAGTAGVLIGYCPQQDA 4778
Cdd:PRK10851   10 KSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGH--IRF---HGTDVSRLHARDRKVGFVFQHYA 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4779 LDELLTGWEHLYYycSLRGIPRQCIPEVAG------DLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDE 4852
Cdd:PRK10851   85 LFRHMTVFDNIAF--GLTVLPRRERPNAAAikakvtQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLDE 162
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4853 PSSGMDPCSKRYL--WqtiMKEVREGC--AAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:PRK10851  163 PFGALDAQVRKELrrW---LRQLHEELkfTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQV 224
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
4692-4908 2.87e-14

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 76.39  E-value: 2.87e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRFFQN----------------IIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGhaiirtpmg 4755
Cdd:PRK13546    9 NVTKEYRIYRTNkermkdalipkhknktFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVG--------- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4756 davDLSSAGTAGVLigycPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKL 4835
Cdd:PRK13546   80 ---KVDRNGEVSVI----AISAGLSGQLTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKL 152
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871 4836 STALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLG 4908
Cdd:PRK13546  153 GFSINITVNPDILVIDEALSVGDQTFAQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYG 225
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
4683-4911 3.59e-14

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 77.45  E-value: 3.59e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4683 TNGDILVLYNLSKhyrRFFQNIIaVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSS 4762
Cdd:PRK11432    2 TQKNFVVLKNITK---RFGSNTV-IDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFID---GEDVTHRS 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4763 AGTAGVLIGYcpQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALV 4842
Cdd:PRK11432   75 IQQRDICMVF--QSYALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALI 152
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4843 GKPDILLLDEPSSGMDPCSKRYLWQTImKEVRE--GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQ 4911
Cdd:PRK11432  153 LKPKVLLFDEPLSNLDANLRRSMREKI-RELQQqfNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQ 222
cbiO PRK13650
energy-coupling factor transporter ATPase;
4686-4919 4.15e-14

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 76.31  E-value: 4.15e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4686 DILVLYNLSKHYRRFfQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGT 4765
Cdd:PRK13650    3 NIIEVKNLTFKYKED-QEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIID---GDLLTEENVWD 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4766 AGVLIGYCPQQ--------DALDELLTGWEHlyyycslRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLST 4837
Cdd:PRK13650   79 IRHKIGMVFQNpdnqfvgaTVEDDVAFGLEN-------KGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAI 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4838 ALALVGKPDILLLDEPSSGMDPCSKRYLWQTImKEVRE--GCAAVLTSHSMEECeALCTRLAIMVNGSFKCLGSPQHIKN 4915
Cdd:PRK13650  152 AGAVAMRPKIIILDEATSMLDPEGRLELIKTI-KGIRDdyQMTVISITHDLDEV-ALSDRVLVMKNGQVESTSTPRELFS 229

                  ....
gi 767944871 4916 RFGD 4919
Cdd:PRK13650  230 RGND 233
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
3851-4057 5.96e-14

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 75.26  E-value: 5.96e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3851 YEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTII---SMLTGLHPPT--SGTIIINGKNL---QTDLSRVRMELGVCPQ 3922
Cdd:PRK14267   13 YYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLrtfNRLLELNEEArvEGEVRLFGRNIyspDVDPIEVRREVGMVFQ 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3923 QDILLDNLTVREHLLLFASIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTR----ALSGGLKRKLSLGIAFMGMSRTVV 3998
Cdd:PRK14267   93 YPNPFPHLTIYDNVAIGVKLNGLVKSKKELDERVEWALKKAALWDEVKDRLNdypsNLSGGQRQRLVIARALAMKPKILL 172
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 3999 LDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGP 4057
Cdd:PRK14267  173 MDEPTANIDPVGTAKIEELLFELKKEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGP 231
ABC2_membrane_3 pfam12698
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter ...
3527-3728 6.63e-14

ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter family pfam01061.


Pssm-ID: 463674 [Multi-domain]  Cd Length: 345  Bit Score: 76.66  E-value: 6.63e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3527 LQDMIERAIILVQTGQEALEPAAQTQAAPYPCHTSDLF---LNNVGFFFPLIMMLTWMVSVASMVRKLVYEQEIQIEEYM 3603
Cdd:pfam12698  116 ILNALQSLLQQLNASALVLLLEALSTSAPIPVESTPLFnpqSGYAYYLVGLILMIIILIGAAIIAVSIVEEKESRIKERL 195
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3604 RMMGVHPVIHFLAWFLENMAVLTISSATLAIVLKTSGIFAHSNTFIVFLFLLdFGMSVVMLSYLLSAFFSQAnTAALCTS 3683
Cdd:pfam12698  196 LVSGVSPLQYWLGKILGDFLVGLLQLLIILLLLFGIGIPFGNLGLLLLLFLL-YGLAYIALGYLLGSLFKNS-EDAQSII 273
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 767944871  3684 LVYMISFLPYIVLLVLHNQLSFVNQTFLCLLSTTAFGQGVFFITF 3728
Cdd:pfam12698  274 GIVILLLSGFFGGLFPLEDPPSFLQWIFSIIPFFSPIDGLLRLIY 318
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
3860-4052 7.62e-14

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 77.78  E-value: 7.62e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3860 DLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVC--P---QQDIL-LD----- 3928
Cdd:PRK15439  281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQRLARGLVylPedrQSSGLyLDaplaw 360
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3929 ---NLTVREhLLLFASIKAPQWTKKELHQQVNQTLQDVDltqhqhKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSG 4005
Cdd:PRK15439  361 nvcALTHNR-RGFWIKPARENAVLERYRRALNIKFNHAE------QAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRG 433
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 767944871 4006 VDPCSRHSLWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:PRK15439  434 VDVSARNDIYQLIRSIaAQNVAVLFISSDLEEIEQMADRVLVMHQGEI 481
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
3843-4051 8.45e-14

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 77.66  E-value: 8.45e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3843 TLVSVTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHP--PTSGTIIINGKNLQTDLSRVRMELGVC 3920
Cdd:PRK13549    7 EMKNITKTFGGVKAL-DNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPhgTYEGEIIFEGEELQASNIRDTERAGIA 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3921 --PQQDILLDNLTVREHLLLFAsikapQWTKK------ELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMG 3992
Cdd:PRK13549   86 iiHQELALVKELSVLENIFLGN-----EITPGgimdydAMYLRAQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKALNK 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 3993 MSRTVVLDEPTSGVDPCSRHSLWDIL--LKyREGRTIIFTTHHLDEAEALSDRVAVLQHGR 4051
Cdd:PRK13549  161 QARLLILDEPTASLTESETAVLLDIIrdLK-AHGIACIYISHKLNEVKAISDTICVIRDGR 220
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
4687-4902 1.01e-13

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 74.84  E-value: 1.01e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4687 ILVLYNLSKHYR-----RFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmgdAVDLS 4761
Cdd:TIGR02769    2 LLEVRDVTHTYRtgglfGAKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFR-----GQDLY 76
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4762 SAGTAG---------VLIGYCPQ----QDALDELLTgwEHLYYYCSLRGIPRQcipEVAGDLIRRLHLEA-HADKPVATY 4827
Cdd:TIGR02769   77 QLDRKQrrafrrdvqLVFQDSPSavnpRMTVRQIIG--EPLRHLTSLDESEQK---ARIAELLDMVGLRSeDADKLPRQL 151
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4828 SGGTKRKLSTALALVGKPDILLLDEPSSGMDpcskRYLWQTIMKEVRE-----GCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:TIGR02769  152 SGGQLQRINIARALAVKPKLIVLDEAVSNLD----MVLQAVILELLRKlqqafGTAYLFITHDLRLVQSFCQRVAVMDKG 227
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
3857-4059 1.20e-13

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 75.66  E-value: 1.20e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3857 VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTI----IINGKNLQT-------------DLSRVRMELGV 3919
Cdd:PRK13631   41 ALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIqvgdIYIGDKKNNhelitnpyskkikNFKELRRRVSM 120
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3920 C---PQQDILLDNLtvrEHLLLFASIKAPQwTKKELHQQVNQTLQDVDL-TQHQHKQTRALSGGLKRKLSLGIAFMGMSR 3995
Cdd:PRK13631  121 VfqfPEYQLFKDTI---EKDIMFGPVALGV-KKSEAKKLAKFYLNKMGLdDSYLERSPFGLSGGQKRRVAIAGILAIQPE 196
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 3996 TVVLDEPTSGVDPCSRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPPF 4059
Cdd:PRK13631  197 ILIFDEPTAGLDPKGEHEMMQLILDAKaNNKTVFVITHTMEHVLEVADEVIVMDKGKILKTGTPY 261
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
3842-4051 1.26e-13

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 71.33  E-value: 1.26e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGHKaVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKnlqtdlsrvrMELGVCP 3921
Cdd:cd03221     1 IELENLSKTYGGKL-LLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGST----------VKIGYFE 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QqdilldnltvrehlllfasikapqwtkkelhqqvnqtlqdvdltqhqhkqtraLSGGLKRKLSLGIAFMGMSRTVVLDE 4001
Cdd:cd03221    70 Q-----------------------------------------------------LSGGEKMRLALAKLLLENPNLLLLDE 96
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4002 PTSGVDPCSRHSLWDILLKYRegRTIIFTTHhlDEA--EALSDRVAVLQHGR 4051
Cdd:cd03221    97 PTNHLDLESIEALEEALKEYP--GTVILVSH--DRYflDQVATKIIELEDGK 144
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
4687-4899 1.81e-13

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 75.09  E-value: 1.81e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNG---EVSLTSGHAIIrtpmgDAVDLSSA 4763
Cdd:COG0444     1 LLEVRNLKVYFPTRRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGllpPPGITSGEILF-----DGEDLLKL 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4764 GTA------GVLIGYCPQ--QDALDELLTGWEHLYYycSLR---GIPRQCIPEVAGDLIRRLHL---EAHADKpvatY-- 4827
Cdd:COG0444    76 SEKelrkirGREIQMIFQdpMTSLNPVMTVGDQIAE--PLRihgGLSKAEARERAIELLERVGLpdpERRLDR----Yph 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4828 --SGGTKRKLSTALALVGKPDILLLDEPSSGMDPcskrylwqTI-------MKEVRE--GCAAVLTSHSMEECEALCTRL 4896
Cdd:COG0444   150 elSGGMRQRVMIARALALEPKLLIADEPTTALDV--------TIqaqilnlLKDLQRelGLAILFITHDLGVVAEIADRV 221

                  ...
gi 767944871 4897 AIM 4899
Cdd:COG0444   222 AVM 224
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
3842-4051 1.85e-13

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 76.79  E-value: 1.85e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3842 VTLVSVTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHP--PTSGTIIINGKNLQTDLSRVRMELGV 3919
Cdd:TIGR02633    2 LEMKGIVKTFGGVKAL-DGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPhgTWDGEIYWSGSPLKASNIRDTERAGI 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3920 C--PQQDILLDNLTVREHLLLFASIKAP--QWTKKELHQQVNQTLQDVDLT-QHQHKQTRALSGGLKRKLSLGIAFMGMS 3994
Cdd:TIGR02633   81 ViiHQELTLVPELSVAENIFLGNEITLPggRMAYNAMYLRAKNLLRELQLDaDNVTRPVGDYGGGQQQLVEIAKALNKQA 160
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871  3995 RTVVLDEPTSGVDPCSRHSLWDIL--LKyREGRTIIFTTHHLDEAEALSDRVAVLQHGR 4051
Cdd:TIGR02633  161 RLLILDEPSSSLTEKETEILLDIIrdLK-AHGVACVYISHKLNEVKAVCDTICVIRDGQ 218
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
3858-4052 2.34e-13

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 76.20  E-value: 2.34e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3858 VQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTdlsrvrmelgVCPQQ-------------- 3923
Cdd:PRK10762  268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVT----------RSPQDglangivyisedrk 337
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3924 -DILLDNLTVREHLLLFASIKAPQWTKKELHQQVNQTLQD-VDL----TQHQHKQTRALSGGLKRKLSLGIAFMGMSRTV 3997
Cdd:PRK10762  338 rDGLVLGMSVKENMSLTALRYFSRAGGSLKHADEQQAVSDfIRLfnikTPSMEQAIGLLSGGNQQKVAIARGLMTRPKVL 417
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 3998 VLDEPTSGVDPCSRHSLWDILLKYR-EGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:PRK10762  418 ILDEPTRGVDVGAKKEIYQLINQFKaEGLSIILVSSEMPEVLGMSDRILVMHEGRI 473
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
3861-4066 2.82e-13

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 73.04  E-value: 2.82e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3861 LSLTFYRDQITALLGTNGAGKTTIISMLTGLhPPTSGTIIINGKNLQT----DLSRVRMELGvcpQQDILLDNLTVREHL 3936
Cdd:PRK03695   15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGL-LPGSGSIQFAGQPLEAwsaaELARHRAYLS---QQQTPPFAMPVFQYL 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3937 LLFASIKAPqwtKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTV-------VLDEPTSGVDpC 4009
Cdd:PRK03695   91 TLHQPDKTR---TEAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVVLQVWPDInpagqllLLDEPMNSLD-V 166
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4010 SRHSLWDILLKY--REGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGP------PFCLKEAYG 4066
Cdd:PRK03695  167 AQQAALDRLLSElcQQGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRrdevltPENLAQVFG 231
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
3853-4051 2.97e-13

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 76.26  E-value: 2.97e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPpTSGTIIINGKNLQT----DLSRVRMELGVCPQ------ 3922
Cdd:COG4172   297 GHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLIP-SEGEIRFDGQDLDGlsrrALRPLRRRMQVVFQdpfgsl 375
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3923 ------QDIlldnltVREHLLlfasIKAPQWTKKELHQQVNQTLQDVDLT-QHQHKQTRALSGG------------LKRK 3983
Cdd:COG4172   376 sprmtvGQI------IAEGLR----VHGPGLSAAERRARVAEALEEVGLDpAARHRYPHEFSGGqrqriaiaraliLEPK 445
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3984 LslgiafmgmsrtVVLDEPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGR 4051
Cdd:COG4172   446 L------------LVLDEPTSALDVSVQAQILDLLrdLQREHGLAYLFISHDLAVVRALAHRVMVMKDGK 503
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
4687-4902 4.08e-13

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 72.81  E-value: 4.08e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYrrffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAiirTPMGDAVDLSSAgTA 4766
Cdd:PRK11248    1 MLQISHLYADY----GGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSI---TLDGKPVEGPGA-ER 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4767 GVLI---GYCPQQDALDELLTGWEhlyyycsLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVG 4843
Cdd:PRK11248   73 GVVFqneGLLPWRNVQDNVAFGLQ-------LAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAA 145
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4844 KPDILLLDEPSSGMDPCSKRYLwQTIMKEV--REGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:PRK11248  146 NPQLLLLDEPFGALDAFTREQM-QTLLLKLwqETGKQVLLITHDIEEAVFMATELVLLSPG 205
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
4706-4918 4.48e-13

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 75.57  E-value: 4.48e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGV--LIGYCPQQ------- 4776
Cdd:COG4987   350 VLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITL-----GGVDLRDLDEDDLrrRIAVVPQRphlfdtt 424
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4777 ----------DALDELLtgWEHLyyycslrgiprqcipEVAG--DLIRRL------HLEAHAdkpvATYSGGTKRKLSTA 4838
Cdd:COG4987   425 lrenlrlarpDATDEEL--WAAL---------------ERVGlgDWLAALpdgldtWLGEGG----RRLSGGERRRLALA 483
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4839 LALVGKPDILLLDEPSSGMDPCSKRYLWQTIMkEVREGCAAVLTSHSMEECEAlCTRLAIMVNGSFKCLGSPQHIKNRFG 4918
Cdd:COG4987   484 RALLRDAPILLLDEPTEGLDAATEQALLADLL-EALAGRTVLLITHRLAGLER-MDRILVLEDGRIVEQGTHEELLAQNG 561
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
4706-4902 5.28e-13

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 71.97  E-value: 5.28e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLSSAGTAGVL---IGYCPQQDALdel 4782
Cdd:COG4161    17 ALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFDFSQKPSEKAIRLLrqkVGMVFQQYNL--- 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4783 ltgWEHLYYY-------CSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSS 4855
Cdd:COG4161    94 ---WPHLTVMenlieapCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTA 170
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4856 GMDPcskrylwqTIMKEVRE--------GCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:COG4161   171 ALDP--------EITAQVVEiirelsqtGITQVIVTHEVEFARKVASQVVYMEKG 217
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
4690-4918 5.34e-13

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 75.93  E-value: 5.34e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4690 LYNLSKHYRRffqnIIAVQDISLGIPKGECFGLLGVNGAGKSTTFkmlngevSLTSGHAIIRT--------PMGDAVDLS 4761
Cdd:NF033858    4 LEGVSHRYGK----TVALDDVSLDIPAGCMVGLIGPDGVGKSSLL-------SLIAGARKIQQgrvevlggDMADARHRR 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4762 SAGTAgvlIGYCPQQdaldeL-------LTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRK 4834
Cdd:NF033858   73 AVCPR---IAYMPQG-----LgknlyptLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQK 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4835 LSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTI--MKEVREGcAAVLTSHS-MEECEAlCTRLAIMVNGsfKCL--GS 4909
Cdd:NF033858  145 LGLCCALIHDPDLLILDEPTTGVDPLSRRQFWELIdrIRAERPG-MSVLVATAyMEEAER-FDWLVAMDAG--RVLatGT 220

                  ....*....
gi 767944871 4910 PQHIKNRFG 4918
Cdd:NF033858  221 PAELLARTG 229
cbiO PRK13642
energy-coupling factor transporter ATPase;
3850-4052 5.96e-13

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 72.82  E-value: 5.96e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3850 EYEGHKAVVQ--DLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTD-LSRVRMELGVCPQQ-DI 3925
Cdd:PRK13642   13 KYEKESDVNQlnGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAEnVWNLRRKIGMVFQNpDN 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3926 LLDNLTVREHLLLfaSIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSG 4005
Cdd:PRK13642   93 QFVGATVEDDVAF--GMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSM 170
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 767944871 4006 VDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAeALSDRVAVLQHGRL 4052
Cdd:PRK13642  171 LDPTGRQEIMRVIheIKEKYQLTVLSITHDLDEA-ASSDRILVMKAGEI 218
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
4687-4902 6.51e-13

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 72.27  E-value: 6.51e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYrrffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLSSAGTA 4766
Cdd:PRK11701    6 LLSVRGLTKLY----GPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQLRDLYALSEA 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4767 ----------GVLigycpQQDALDEL---------------LTGWEHlyyYCSLRgiprqcipEVAGDLIRRLHLEAHA- 4820
Cdd:PRK11701   82 errrllrtewGFV-----HQHPRDGLrmqvsaggnigerlmAVGARH---YGDIR--------ATAGDWLERVEIDAARi 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4821 -DKPvATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAI 4898
Cdd:PRK11701  146 dDLP-TTFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRElGLAVVIVTHDLAVARLLAHRLLV 224

                  ....
gi 767944871 4899 MVNG 4902
Cdd:PRK11701  225 MKQG 228
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
3847-4052 7.80e-13

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 75.14  E-value: 7.80e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3847 VTKEYEGH-KAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT-DLSRVRMELGVCPQQD 3924
Cdd:TIGR02203  336 VTFRYPGRdRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADyTLASLRRQVALVSQDV 415
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3925 ILLDNlTVREHLLLFASIKAPQwtkkelhQQVNQTLQDVDLTQ---------HQHKQTRA--LSGGLKRKLSLGIAFMGM 3993
Cdd:TIGR02203  416 VLFND-TIANNIAYGRTEQADR-------AEIERALAAAYAQDfvdklplglDTPIGENGvlLSGGQRQRLAIARALLKD 487
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871  3994 SRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEAlSDRVAVLQHGRL 4052
Cdd:TIGR02203  488 APILILDEATSALDNESERLVQAALERLMQGRTTLVIAHRLSTIEK-ADRIVVMDDGRI 545
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
4709-4913 8.10e-13

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 73.60  E-value: 8.10e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4709 DISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHaiIRtpMGDAVDLSSAgtAGV-------LIGYCPQQDALDE 4781
Cdd:COG4148    17 DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGR--IR--LGGEVLQDSA--RGIflpphrrRIGYVFQEARLFP 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4782 LLTGWEHLYYycSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCS 4861
Cdd:COG4148    91 HLSVRGNLLY--GRKRAPRAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLAR 168
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 4862 KR----YLwQTIMKEVRegCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:COG4148   169 KAeilpYL-ERLRDELD--IPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEV 221
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
4708-4884 1.02e-12

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 69.96  E-value: 1.02e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4708 QDISLGIPKGECFGLLGVNGAGKSTTFKMLNG--EVSLTSGHAIIRtpmGDAVDLSSAGTagvlIGYCPQQDALDELLTG 4785
Cdd:cd03232    24 NNISGYVKPGTLTALMGESGAGKTTLLDVLAGrkTAGVITGEILIN---GRPLDKNFQRS----TGYVEQQDVHSPNLTV 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4786 WEHLYYYCSLRGIprqcipevagdlirrlhleahadkpvatySGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYL 4865
Cdd:cd03232    97 REALRFSALLRGL-----------------------------SVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQAAYNI 147
                         170
                  ....*....|....*....
gi 767944871 4866 WQTIMKEVREGCAAVLTSH 4884
Cdd:cd03232   148 VRFLKKLADSGQAILCTIH 166
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
4701-4915 1.30e-12

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 71.17  E-value: 1.30e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4701 FQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVD-LSSAGTA--GVL-----IGY 4772
Cdd:PRK11300   15 FGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLR---GQHIEgLPGHQIArmGVVrtfqhVRL 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4773 CPQQDALDELL--------TGWEH-LYYYCSLRGIPRQCIpEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVG 4843
Cdd:PRK11300   92 FREMTVIENLLvaqhqqlkTGLFSgLLKTPAFRRAESEAL-DRAATWLERVGLLEHANRQAGNLAYGQQRRLEIARCMVT 170
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871 4844 KPDILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKN 4915
Cdd:PRK11300  171 QPEILMLDEPAAGLNPKETKELDELIAELRNEhNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEIRN 243
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
3872-4058 1.64e-12

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 70.38  E-value: 1.64e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3872 ALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNlQTDLSRVRMELGVCPQQDILLDNLTVREH--LLLFASIK--APQw 3947
Cdd:PRK10771   29 AILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQD-HTTTPPSRRPVSMLFQENNLFSHLTVAQNigLGLNPGLKlnAAQ- 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3948 tkkelHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGR-- 4025
Cdd:PRK10771  107 -----REKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSQVCQERql 181
                         170       180       190
                  ....*....|....*....|....*....|...
gi 767944871 4026 TIIFTTHHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK10771  182 TLLMVSHSLEDAARIAPRSLVVADGRIAWDGPT 214
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
4707-4881 1.79e-12

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 70.91  E-value: 1.79e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSS------AGTAGVLigycPQQDALD 4780
Cdd:COG4559    17 LDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRL-----NGRPLAAwspwelARRRAVL----PQHSSLA 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4781 ELLTGWE--------HLYYYCSLRGIPRQCIpEVAGdlirrlhLEAHADKPVATYSGGTKRK--LSTALALV-----GKP 4845
Cdd:COG4559    88 FPFTVEEvvalgrapHGSSAAQDRQIVREAL-ALVG-------LAHLAGRSYQTLSGGEQQRvqLARVLAQLwepvdGGP 159
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 767944871 4846 DILLLDEPSSGMDPcskrYLWQTIMKEVR----EGCA--AVL 4881
Cdd:COG4559   160 RWLFLDEPTSALDL----AHQHAVLRLARqlarRGGGvvAVL 197
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
4701-4921 1.90e-12

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 70.81  E-value: 1.90e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4701 FQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTS---------GHAIIRT-PMGDAVDLSSAGTagvli 4770
Cdd:PRK09984   14 FNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKsagshiellGRTVQREgRLARDIRKSRANT----- 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4771 GYCPQQDALDELLTGWEHLYYyCSLRGIP--RQCI-------PEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALAL 4841
Cdd:PRK09984   89 GYIFQQFNLVNRLSVLENVLI-GALGSTPfwRTCFswftreqKQRALQALTRVGMVHFAHQRVSTLSGGQQQRVAIARAL 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4842 VGKPDILLLDEPSSGMDPCSKRYLWQTIMK-EVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKN-RFGD 4919
Cdd:PRK09984  168 MQQAKVILADEPIASLDPESARIVMDTLRDiNQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQQFDNeRFDH 247

                  ..
gi 767944871 4920 GY 4921
Cdd:PRK09984  248 LY 249
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
3855-4052 2.02e-12

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 73.41  E-value: 2.02e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3855 KAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGV--CP----QQDIL-- 3926
Cdd:PRK11288  266 PGLREPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRDAIRAGImlCPedrkAEGIIpv 345
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3927 ---LDNLTV--REHLLLFASIKAPQWTKKELHQQVnqtlQDVDL-TQHQHKQTRALSGG------LKRKLSLGIafmgms 3994
Cdd:PRK11288  346 hsvADNINIsaRRHHLRAGCLINNRWEAENADRFI----RSLNIkTPSREQLIMNLSGGnqqkaiLGRWLSEDM------ 415
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 3995 RTVVLDEPTSGVDPCSRHSLWDILLKYRE-GRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:PRK11288  416 KVILLDEPTRGIDVGAKHEIYNVIYELAAqGVAVLFVSSDLPEVLGVADRIVVMREGRI 474
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
3856-4053 2.23e-12

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 69.81  E-value: 2.23e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3856 AVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMEL-----GVCPQQDILLDNL 3930
Cdd:PRK10584   24 SILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARAKLrakhvGFVFQSFMLIPTL 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3931 TVREHLLLFASIKAPqwTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCS 4010
Cdd:PRK10584  104 NALENVELPALLRGE--SSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQT 181
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 767944871 4011 RHSLWDIL--LKYREGRTIIFTTHHLDEAeALSDRVAVLQHGRLR 4053
Cdd:PRK10584  182 GDKIADLLfsLNREHGTTLILVTHDLQLA-ARCDRRLRLVNGQLQ 225
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
4706-4916 2.31e-12

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 70.92  E-value: 2.31e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGeVSLTSGHAIirTPMGDAVDLSSA----GTAGVLIgycpqQDALDE 4781
Cdd:PRK13647   20 ALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNG-IYLPQRGRV--KVMGREVNAENEkwvrSKVGLVF-----QDPDDQ 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4782 LL--TGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDP 4859
Cdd:PRK13647   92 VFssTVWDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDP 171
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4860 CSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKNR 4916
Cdd:PRK13647  172 RGQETLMEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKSLLTDE 228
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
4695-4916 2.54e-12

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 72.94  E-value: 2.54e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4695 KHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNG--EVSLTSGHAIIRTPMGDAVDLSSAGTAGVLIGY 4772
Cdd:TIGR02633    5 KGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGvyPHGTWDGEIYWSGSPLKASNIRDTERAGIVIIH 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4773 cpQQDALDELLTGWEHLY--YYCSLRGiPRQCIPEV---AGDLIRRLHLEAHAD-KPVATYSGGTKRKLSTALALVGKPD 4846
Cdd:TIGR02633   85 --QELTLVPELSVAENIFlgNEITLPG-GRMAYNAMylrAKNLLRELQLDADNVtRPVGDYGGGQQQLVEIAKALNKQAR 161
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4847 ILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGsfkclgspQHIKNR 4916
Cdd:TIGR02633  162 LLILDEPSSSLTEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDG--------QHVATK 223
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
4692-4913 2.80e-12

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 70.60  E-value: 2.80e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRrffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTAGVLIG 4771
Cdd:PRK13652    8 DLCYSYS---GSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIR---GEPITKENIREVRKFVG 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4772 YCPQQ--DALDELLTGWEHLYYYCSLrGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILL 4849
Cdd:PRK13652   82 LVFQNpdDQIFSPTVEQDIAFGPINL-GLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLV 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4850 LDEPSSGMDPCSKRYLWQTIMK-EVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:PRK13652  161 LDEPTAGLDPQGVKELIDFLNDlPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEI 225
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
4709-4911 3.34e-12

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 69.76  E-value: 3.34e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4709 DISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGhAIIRTPmgdavdlssagtaGVLIGYCPQQDALDELLTgwEH 4788
Cdd:PRK09544   22 DVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEG-VIKRNG-------------KLRIGYVPQKLYLDTTLP--LT 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4789 LYYYCSLR-GIPRQCIpevaGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQ 4867
Cdd:PRK09544   86 VNRFLRLRpGTKKEDI----LPALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALYD 161
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 767944871 4868 TIMKEVRE-GCAAVLTSHSM-----EECEALCtrlaimVNGSFKCLGSPQ 4911
Cdd:PRK09544  162 LIDQLRRElDCAVLMVSHDLhlvmaKTDEVLC------LNHHICCSGTPE 205
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
4688-4904 4.96e-12

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 72.25  E-value: 4.96e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHyrrfFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAG--- 4764
Cdd:PRK11288    5 LSFDGIGKT----FPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILID---GQEMRFASTTaal 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4765 TAGVLIGYcpQQDALDELLTGWEHLYyycsLRGIP-------RQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLST 4837
Cdd:PRK11288   78 AAGVAIIY--QELHLVPEMTVAENLY----LGQLPhkggivnRRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEI 151
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4838 ALALVGKPDILLLDEPSSGMdpcSKRYLWQ--TIMKEVR-EGCAAVLTSHSMEECEALCTRLAIMVNGSF 4904
Cdd:PRK11288  152 AKALARNARVIAFDEPTSSL---SAREIEQlfRVIRELRaEGRVILYVSHRMEEIFALCDAITVFKDGRY 218
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
4707-4911 5.39e-12

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 69.42  E-value: 5.39e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSS------AGTAGVLigycPQQDALD 4780
Cdd:PRK13548   18 LDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRL-----NGRPLADwspaelARRRAVL----PQHSSLS 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4781 ---------EL-LTGWehlyyycSLRGIPRQCIPEVAgdlIRRLHLEAHADKPVATYSGGTKRKLSTALALV------GK 4844
Cdd:PRK13548   89 fpftveevvAMgRAPH-------GLSRAEDDALVAAA---LAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAqlwepdGP 158
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 4845 PDILLLDEPSSGMDPcskrYLWQTIMKEVRE-----GCA--AVLtsHSMEECEALCTRLAIMVNGSFKCLGSPQ 4911
Cdd:PRK13548  159 PRWLLLDEPTSALDL----AHQHHVLRLARQlaherGLAviVVL--HDLNLAARYADRIVLLHQGRLVADGTPA 226
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
3855-4057 8.25e-12

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 71.70  E-value: 8.25e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3855 KAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL----QTDLSRVrmeLGVCPQqDILLDNL 3930
Cdd:COG4618   345 RPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLsqwdREELGRH---IGYLPQ-DVELFDG 420
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3931 TVREHLLLFAS------IKAPQwtkkelhqqvnqtLQDV-DLTQHQHK--QTR------ALSGGLKRKLSLGIAFMGMSR 3995
Cdd:COG4618   421 TIAENIARFGDadpekvVAAAK-------------LAGVhEMILRLPDgyDTRigeggaRLSGGQRQRIGLARALYGDPR 487
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871 3996 TVVLDEPTSGVDPCSRHSLWDILLKYRE-GRTIIFTTHHLdEAEALSDRVAVLQHGRLRCCGP 4057
Cdd:COG4618   488 LVVLDEPNSNLDDEGEAALAAAIRALKArGATVVVITHRP-SLLAAVDKLLVLRDGRVQAFGP 549
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
3847-4051 9.35e-12

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 71.30  E-value: 9.35e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKN---------LQTDLSRVRMEL 3917
Cdd:PRK10982    4 ISKSFPGVKAL-DNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEidfksskeaLENGISMVHQEL 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3918 GVCPQQDIlLDNLTVREHLLlfasiKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTV 3997
Cdd:PRK10982   83 NLVLQRSV-MDNMWLGRYPT-----KGMFVDQDKMYRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIV 156
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 3998 VLDEPTSGVDPCSRHSLWDILLKYRE-GRTIIFTTHHLDEAEALSDRVAVLQHGR 4051
Cdd:PRK10982  157 IMDEPTSSLTEKEVNHLFTIIRKLKErGCGIVYISHKMEEIFQLCDEITILRDGQ 211
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
4706-4919 1.00e-11

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 71.46  E-value: 1.00e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGevsltsghaiIRTPMGDAVDLSSAGTAgVLIGycpqqDALDELLTG 4785
Cdd:PRK13545   39 ALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAG----------VTMPNKGTVDIKGSAAL-IAIS-----SGLNGQLTG 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4786 WEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEP-SSGMDPCSKRY 4864
Cdd:PRK13545  103 IENIELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEAlSVGDQTFTKKC 182
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 4865 LWQtiMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIKNRFGD 4919
Cdd:PRK13545  183 LDK--MNEFKEqGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVVDHYDE 236
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
4687-4902 1.19e-11

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 68.26  E-value: 1.19e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYRRffqnIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKM------LNGEVSLT-----SGHAIIrTPMG 4755
Cdd:PRK14239    5 ILQVSDLSVYYNK----KKALNSVSLDFYPNEITALIGPSGSGKSTLLRSinrmndLNPEVTITgsivyNGHNIY-SPRT 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4756 DAVDLSSAgtagvlIGYCPQQDALDELlTGWEHLYYYCSLRGIP-RQCIPEVAGDLIR----------RLHLEAHAdkpv 4824
Cdd:PRK14239   80 DTVDLRKE------IGMVFQQPNPFPM-SIYENVVYGLRLKGIKdKQVLDEAVEKSLKgasiwdevkdRLHDSALG---- 148
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4825 atYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMkEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:PRK14239  149 --LSGGQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLL-GLKDDYTMLLVTRSMQQASRISDRTGFFLDG 223
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
4693-4896 1.57e-11

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 67.18  E-value: 1.57e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4693 LSKHYRRFFQNIIAV-QDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLSSagtagvLIG 4771
Cdd:PRK13543   12 LAAHALAFSRNEEPVfGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGDRSR------FMA 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4772 YCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPevaGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLD 4851
Cdd:PRK13543   86 YLGHLPGLKADLSTLENLHFLCGLHGRRAKQMP---GSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLD 162
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 767944871 4852 EPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRL 4896
Cdd:PRK13543  163 EPYANLDLEGITLVNRMISAHLRGGGAALVTTHGAYAAPPVRTRM 207
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
7-82 1.66e-11

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 71.58  E-value: 1.66e-11
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871     7 QFKALLWKNWLCRLRNPVLFLAEFFWPCILFVILTVLRFQEPPRYRDICYLQPRDLPSCGVIPFVQSLLCNTGSRC 82
Cdd:TIGR01257    6 QIQLLLWKNWTLRKRQKIRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPC 81
PLN03211 PLN03211
ABC transporter G-25; Provisional
3869-4051 1.72e-11

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 70.68  E-value: 1.72e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3869 QITALLGTNGAGKTTIISMLTG-LHPPT-SGTIIINGKNLQTDLSRvrmELGVCPQQDILLDNLTVREHLLLFASIKAPQ 3946
Cdd:PLN03211   95 EILAVLGPSGSGKSTLLNALAGrIQGNNfTGTILANNRKPTKQILK---RTGFVTQDDILYPHLTVRETLVFCSLLRLPK 171
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3947 -WTKKELHQQVNQTLQDVDLTQHQHKQT-----RALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLK 4020
Cdd:PLN03211  172 sLTKQEKILVAESVISELGLTKCENTIIgnsfiRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRLVLTLGS 251
                         170       180       190
                  ....*....|....*....|....*....|...
gi 767944871 4021 Y-REGRTIIFTTHH-LDEAEALSDRVAVLQHGR 4051
Cdd:PLN03211  252 LaQKGKTIVTSMHQpSSRVYQMFDSVLVLSEGR 284
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
3842-4066 1.80e-11

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 70.92  E-value: 1.80e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIIngknLQTDLSRVRMELGVCP 3921
Cdd:NF033858    2 ARLEGVSHRY-GKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEV----LGGDMADARHRRAVCP 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 QqdI----------LLDNLTVREHLLLFA-----SikapqwtKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSL 3986
Cdd:NF033858   77 R--IaympqglgknLYPTLSVFENLDFFGrlfgqD-------AAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGL 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3987 GIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGR---TIIFTTHHLDEAEALsDRVAVLQHGRLRCCGPPFCLKE 4063
Cdd:NF033858  148 CCALIHDPDLLILDEPTTGVDPLSRRQFWELIDRIRAERpgmSVLVATAYMEEAERF-DWLVAMDAGRVLATGTPAELLA 226

                  ...
gi 767944871 4064 AYG 4066
Cdd:NF033858  227 RTG 229
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
3853-4048 2.22e-11

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 67.05  E-value: 2.22e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTdLS--RVRMELGVCPQQDILLDNl 3930
Cdd:PRK10247   18 GDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDIST-LKpeIYRQQVSYCAQTPTLFGD- 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3931 TVREHLLLFASI--KAPQwtkkelHQQVNQTLQDVDLTQHQ-HKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVD 4007
Cdd:PRK10247   96 TVYDNLIFPWQIrnQQPD------PAIFLDDLERFALPDTIlTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITSALD 169
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 767944871 4008 PCSRHSLWDILLKYREGRTI--IFTTHHLDEAEAlSDRVAVLQ 4048
Cdd:PRK10247  170 ESNKHNVNEIIHRYVREQNIavLWVTHDKDEINH-ADKVITLQ 211
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
3847-4051 2.73e-11

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 70.13  E-value: 2.73e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTdLSRVRMELGVC-PQQD- 3924
Cdd:PRK10790  346 VSFAYRDDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSS-LSHSVLRQGVAmVQQDp 424
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3925 -ILLDNltvrehllLFASIKAPQWTKKELHQQVNQTLQDVDLTQ------HQH--KQTRALSGGLKRKLSLGIAFMGMSR 3995
Cdd:PRK10790  425 vVLADT--------FLANVTLGRDISEEQVWQALETVQLAELARslpdglYTPlgEQGNNLSVGQKQLLALARVLVQTPQ 496
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 3996 TVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDE-AEAlsDRVAVLQHGR 4051
Cdd:PRK10790  497 ILILDEATANIDSGTEQAIQQALAAVREHTTLVVIAHRLSTiVEA--DTILVLHRGQ 551
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
3851-4052 3.01e-11

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 69.87  E-value: 3.01e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3851 YEGhKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTsGTIIINGKNL-QTDLSRVRMELGVCPQQDILLDN 3929
Cdd:PRK11174  360 PDG-KTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGFLPYQ-GSLKINGIELrELDPESWRKHLSWVGQNPQLPHG 437
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3930 lTVREHLLLfASIKAPQwtkkelhQQVNQTLQDVDLTQHQHK-----------QTRALSGGLKRKLSLGIAFMGMSRTVV 3998
Cdd:PRK11174  438 -TLRDNVLL-GNPDASD-------EQLQQALENAWVSEFLPLlpqgldtpigdQAAGLSVGQAQRLALARALLQPCQLLL 508
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 767944871 3999 LDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEALsDRVAVLQHGRL 4052
Cdd:PRK11174  509 LDEPTASLDAHSEQLVMQALNAASRRQTTLMVTHQLEDLAQW-DQIWVMQDGQI 561
cbiO PRK13643
energy-coupling factor transporter ATPase;
4706-4913 3.50e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 67.45  E-value: 3.50e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGhaIIRtpMGDAVDLSSAGT---------AGVLIGYcPQQ 4776
Cdd:PRK13643   21 ALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEG--KVT--VGDIVVSSTSKQkeikpvrkkVGVVFQF-PES 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4777 DALDEllTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHA-DKPVATYSGGTKRKLSTALALVGKPDILLLDEPSS 4855
Cdd:PRK13643   96 QLFEE--TVLKDVAFGPQNFGIPKEKAEKIAAEKLEMVGLADEFwEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTA 173
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4856 GMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:PRK13643  174 GLDPKARIEMMQLFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDV 231
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
4688-4858 3.51e-11

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 64.01  E-value: 3.51e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYrrffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGhaIIRTPmgdavdlssagtAG 4767
Cdd:cd03221     1 IELENLSKTY----GGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEG--IVTWG------------ST 62
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4768 VLIGYCPQqdaldelltgwehlyyycslrgiprqcipevagdlirrlhleahadkpvatYSGGTKRKLSTALALVGKPDI 4847
Cdd:cd03221    63 VKIGYFEQ---------------------------------------------------LSGGEKMRLALAKLLLENPNL 91
                         170
                  ....*....|.
gi 767944871 4848 LLLDEPSSGMD 4858
Cdd:cd03221    92 LLLDEPTNHLD 102
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
4701-4913 3.52e-11

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 67.34  E-value: 3.52e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4701 FQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTAGVligycPQQDAld 4780
Cdd:PRK13638   11 YQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQ---GKPLDYSKRGLLAL-----RQQVA-- 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4781 ELLTGWEHLYYYC--------SLR--GIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLL 4850
Cdd:PRK13638   81 TVFQDPEQQIFYTdidsdiafSLRnlGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLL 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871 4851 DEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:PRK13638  161 DEPTAGLDPAGRTQMIAIIRRIVAQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEV 223
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
4687-4913 3.78e-11

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 66.96  E-value: 3.78e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYrrffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTA 4766
Cdd:PRK11231    2 TLRTENLTVGY----GTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLG---DKPISMLSSRQL 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4767 GVLIGYCPQQDALDELLTGWEHLYY----YCSLRGipR-----QCIPEVAgdlIRRLHLEAHADKPVATYSGGTKRKLST 4837
Cdd:PRK11231   75 ARRLALLPQHHLTPEGITVRELVAYgrspWLSLWG--RlsaedNARVNQA---MEQTRINHLADRRLTDLSGGQRQRAFL 149
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4838 ALALVGKPDILLLDEPSSGMDpCSKRYLWQTIMKEVR-EGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:PRK11231  150 AMVLAQDTPVVLLDEPTTYLD-INHQVELMRLMRELNtQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEV 225
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
3851-4045 4.25e-11

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 66.73  E-value: 4.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3851 YEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTII---SMLTGLHPP--TSGTIIINGKNL---QTDLSRVRMELGVCPQ 3922
Cdd:PRK14243   19 YYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILrcfNRLNDLIPGfrVEGKVTFHGKNLyapDVDPVEVRRRIGMVFQ 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3923 QDILLDNlTVREHLLLFASIKAPQWTKKELhqqVNQTLQDV---DLTQHQHKQT-RALSGGLKRKLSLGIAFMGMSRTVV 3998
Cdd:PRK14243   99 KPNPFPK-SIYDNIAYGARINGYKGDMDEL---VERSLRQAalwDEVKDKLKQSgLSLSGGQQQRLCIARAIAVQPEVIL 174
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 767944871 3999 LDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEALSDRVA 4045
Cdd:PRK14243  175 MDEPCSALDPISTLRIEELMHELKEQYTIIIVTHNMQQAARVSDMTA 221
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
4706-4887 4.26e-11

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 69.40  E-value: 4.26e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGV--LIGYCPQQDAldeLL 4783
Cdd:COG4988   352 ALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILI-----NGVDLSDLDPASWrrQIAWVPQNPY---LF 423
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4784 TGwehlyyycSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATY---------------SGGTKRKLSTALALVGKPDIL 4848
Cdd:COG4988   424 AG--------TIRENLRLGRPDASDEELEAALEAAGLDEFVAALpdgldtplgeggrglSGGQAQRLALARALLRDAPLL 495
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 767944871 4849 LLDEPSSGMDPCSKRYLWQTImKEVREGCAAVLTSHSME 4887
Cdd:COG4988   496 LLDEPTAHLDAETEAEILQAL-RRLAKGRTVILITHRLA 533
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
4710-4884 5.69e-11

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 65.21  E-value: 5.69e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4710 ISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHaIIRTPMGDAVDLSSAGTAGVLIGYcpqQDALDELLTGWEHL 4789
Cdd:cd03231    19 LSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGR-VLLNGGPLDFQRDSIARGLLYLGH---APGIKTTLSVLENL 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4790 YYYCSLrgiprqCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTI 4869
Cdd:cd03231    95 RFWHAD------HSDEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAM 168
                         170
                  ....*....|....*
gi 767944871 4870 MKEVREGCAAVLTSH 4884
Cdd:cd03231   169 AGHCARGGMVVLTTH 183
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
4709-4858 7.31e-11

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 68.42  E-value: 7.31e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4709 DISLGIPKGECFGLLGVNGAGKSTTFKMLNGevsltsghaiirtpmgdaVDLSSAGTA----GVLIGYCPQQDALDELLT 4784
Cdd:TIGR03719   23 DISLSFFPGAKIGVLGLNGAGKSTLLRIMAG------------------VDKDFNGEArpqpGIKVGYLPQEPQLDPTKT 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4785 GWEHLYYYCS--LRGIPR-------------------------QCIPEVAG--DLIRRLHLEAHA------DKPVATYSG 4829
Cdd:TIGR03719   85 VRENVEEGVAeiKDALDRfneisakyaepdadfdklaaeqaelQEIIDAADawDLDSQLEIAMDAlrcppwDADVTKLSG 164
                          170       180
                   ....*....|....*....|....*....
gi 767944871  4830 GTKRKLSTALALVGKPDILLLDEPSSGMD 4858
Cdd:TIGR03719  165 GERRRVALCRLLLSKPDMLLLDEPTNHLD 193
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
3853-4048 7.43e-11

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 64.83  E-value: 7.43e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKnlqtDLSRVRMELgvcpQQDILL----- 3927
Cdd:PRK13538   12 DERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGE----PIRRQRDEY----HQDLLYlghqp 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3928 ---DNLTVREHLLLFASIKAPQWTkkelhQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLgiAFMGMSRTV--VLDEP 4002
Cdd:PRK13538   84 gikTELTALENLRFYQRLHGPGDD-----EALWEALAQVGLAGFEDVPVRQLSAGQQRRVAL--ARLWLTRAPlwILDEP 156
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4003 -----TSGVDPCSRHslwdILLKYREGRTIIFTTHHldEAEALSDRVAVLQ 4048
Cdd:PRK13538  157 ftaidKQGVARLEAL----LAQHAEQGGMVILTTHQ--DLPVASDKVRKLR 201
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
4675-4858 7.47e-11

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 68.68  E-value: 7.47e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4675 EKRVFEGRTNGDILVLY-NLSKHYRRFfqniiaVQDISLG-IPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGhaiirt 4752
Cdd:PRK13409  327 EERPPRDESERETLVEYpDLTKKLGDF------SLEVEGGeIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEG------ 394
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4753 pmgdAVDLSsagtagVLIGYCPQ----------QDALDELLTGWEHLYYYcslrgiprqcipevaGDLIRRLHLEAHADK 4822
Cdd:PRK13409  395 ----EVDPE------LKISYKPQyikpdydgtvEDLLRSITDDLGSSYYK---------------SEIIKPLQLERLLDK 449
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 767944871 4823 PVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMD 4858
Cdd:PRK13409  450 NVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLD 485
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
4707-4905 1.00e-10

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 67.93  E-value: 1.00e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4707 VQDISLGIPKGECFGLLGVNGAGKSTTFKML--------NGEVSLTSGHAIIRTPMgDAVdlsSAGTAGV-----LIGYC 4773
Cdd:TIGR02633  276 VDDVSFSLRRGEILGVAGLVGAGRTELVQALfgaypgkfEGNVFINGKPVDIRNPA-QAI---RAGIAMVpedrkRHGIV 351
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4774 PQQdALDELLTgWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLE-AHADKPVATYSGGTKRKLSTALALVGKPDILLLDE 4852
Cdd:TIGR02633  352 PIL-GVGKNIT-LSVLKSFCFKMRIDAAAELQIIGSAIQRLKVKtASPFLPIGRLSGGNQQKAVLAKMLLTNPRVLILDE 429
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 767944871  4853 PSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFK 4905
Cdd:TIGR02633  430 PTRGVDVGAKYEIYKLINQLAQEGVAIIVVSSELAEVLGLSDRVLVIGEGKLK 482
hmuV PRK13547
heme ABC transporter ATP-binding protein;
3854-4058 1.02e-10

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 66.00  E-value: 1.02e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3854 HKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPT--------SGTIIINGKNL-QTDLSRVRMELGVCPQQD 3924
Cdd:PRK13547   13 HRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGgaprgarvTGDVTLNGEPLaAIDAPRLARLRAVLPQAA 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3925 ILLDNLTVREHLLL--FASIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGG-LKR--------KLSLGIAFMGM 3993
Cdd:PRK13547   93 QPAFAFSAREIVLLgrYPHARRAGALTHRDGEIAWQALALAGATALVGRDVTTLSGGeLARvqfarvlaQLWPPHDAAQP 172
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 3994 SRTVVLDEPTSGVDPCSRHSLWDILLKY-REGRTIIFT-THHLDEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:PRK13547  173 PRYLLLDEPTAALDLAHQHRLLDTVRRLaRDWNLGVLAiVHDPNLAARHADRIAMLADGAIVAHGAP 239
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
3854-4053 1.28e-10

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 67.54  E-value: 1.28e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3854 HKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPT-SGTIIINGK--NLQTDLSRVRMELGVCPQ---QDILL 3927
Cdd:TIGR02633  272 HRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPGKfEGNVFINGKpvDIRNPAQAIRAGIAMVPEdrkRHGIV 351
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3928 DNLTVREHLLL-----FASIKAPQWTKKElhQQVNQTLQDVDL-TQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDE 4001
Cdd:TIGR02633  352 PILGVGKNITLsvlksFCFKMRIDAAAEL--QIIGSAIQRLKVkTASPFLPIGRLSGGNQQKAVLAKMLLTNPRVLILDE 429
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 767944871  4002 PTSGVDPCSRHSLWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVLQHGRLR 4053
Cdd:TIGR02633  430 PTRGVDVGAKYEIYKLINQLaQEGVAIIVVSSELAEVLGLSDRVLVIGEGKLK 482
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
4684-4887 1.75e-10

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 64.45  E-value: 1.75e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4684 NGDILVLYNLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIR-TPMGDavdLSS 4762
Cdd:PRK11629    2 NKILLQCDNLCKRYQEGSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNgQPMSK---LSS 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4763 AGTAGVL---IGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTAL 4839
Cdd:PRK11629   79 AAKAELRnqkLGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIAR 158
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 767944871 4840 ALVGKPDILLLDEPSSGMDPCSKRYLWQTIMK-EVREGCAAVLTSHSME 4887
Cdd:PRK11629  159 ALVNNPRLVLADEPTGNLDARNADSIFQLLGElNRLQGTAFLVVTHDLQ 207
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
3847-4052 1.77e-10

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 64.13  E-value: 1.77e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSR----VRMELGVCPQ 3922
Cdd:PRK10908    7 VSKAYLGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNRevpfLRRQIGMIFQ 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3923 QDILLDNLTVREHLLLFASIKAPqwTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEP 4002
Cdd:PRK10908   87 DHHLLMDRTVYDNVAIPLIIAGA--SGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLADEP 164
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4003 TSGVDPCSRHSLWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:PRK10908  165 TGNLDDALSEGILRLFEEFnRVGVTVLMATHDIGLISRRSYRMLTLSDGHL 215
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
4717-4884 1.85e-10

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 67.83  E-value: 1.85e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4717 GECFGLLGVNGAGKSTTFKMLNGEVS---LTSGhaiIRTPMGDAVDLSSAGTagvlIGYCPQQDALDELLTGWEHLYYYC 4793
Cdd:TIGR00956  789 GTLTALMGASGAGKTTLLNVLAERVTtgvITGG---DRLVNGRPLDSSFQRS----IGYVQQQDLHLPTSTVRESLRFSA 861
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4794 SLR---GIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGG----TKRKLSTALALVGKPDILL-LDEPSSGMDPCSKRYL 4865
Cdd:TIGR00956  862 YLRqpkSVSKSEKMEYVEEVIKLLEMESYADAVVGVPGEGlnveQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSI 941
                          170
                   ....*....|....*....
gi 767944871  4866 WQTIMKEVREGCAAVLTSH 4884
Cdd:TIGR00956  942 CKLMRKLADHGQAILCTIH 960
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
4687-4859 1.91e-10

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 64.24  E-value: 1.91e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYRRFfqniIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTA 4766
Cdd:COG1126     1 MIEIENLHKSFGDL----EVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVD---GEDLTDSKKDIN 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4767 GVL--IGYCPQQ-------DALDELLTGWEHLyyycslRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLST 4837
Cdd:COG1126    74 KLRrkVGMVFQQfnlfphlTVLENVTLAPIKV------KKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAI 147
                         170       180
                  ....*....|....*....|..
gi 767944871 4838 ALALVGKPDILLLDEPSSGMDP 4859
Cdd:COG1126   148 ARALAMEPKVMLFDEPTSALDP 169
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
4687-4902 2.07e-10

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 64.72  E-value: 2.07e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKhyrRFFQN----IIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSS 4762
Cdd:COG1101     1 MLELKNLSK---TFNPGtvneKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILI-----DGKDVTK 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4763 ------AGTAG-V----LIGYCPQqdaldelLTGWEHLyyycSL-----------RGIPRQCIPEVAgDLIRRLH--LEA 4818
Cdd:COG1101    73 lpeykrAKYIGrVfqdpMMGTAPS-------MTIEENL----ALayrrgkrrglrRGLTKKRRELFR-ELLATLGlgLEN 140
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4819 HADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLA 4897
Cdd:COG1101   141 RLDTKVGLLSGGQRQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEEnNLTTLMVTHNMEQALDYGNRLI 220

                  ....*
gi 767944871 4898 IMVNG 4902
Cdd:COG1101   221 MMHEG 225
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
3842-4053 2.10e-10

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 64.84  E-value: 2.10e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYE---------------GHKA----VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIIN 3902
Cdd:PRK13546    5 VNIKNVTKEYRiyrtnkermkdalipKHKNktffALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRN 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3903 GknlqtDLSRVRMELGVCPQQdILLDNLTVREHLLLFasikapqwTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKR 3982
Cdd:PRK13546   85 G-----EVSVIAISAGLSGQL-TGIENIEFKMLCMGF--------KRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRA 150
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 3983 KLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYRE-GRTIIFTTHHLDEAEALSDRVAVLQHGRLR 4053
Cdd:PRK13546  151 KLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKIYEFKEqNKTIFFVSHNLGQVRQFCTKIAWIEGGKLK 222
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
3854-4053 2.23e-10

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 66.88  E-value: 2.23e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3854 HKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHP-PTSGTIIINGKNLQTDLSRVRMELGVC------PQQDIL 3926
Cdd:PRK13549  274 HIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPgRWEGEIFIDGKPVKIRNPQQAIAQGIAmvpedrKRDGIV 353
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3927 LDnLTVREHLLLfASIKapQWTK-------KELHQqVNQTLQDVDL-TQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVV 3998
Cdd:PRK13549  354 PV-MGVGKNITL-AALD--RFTGgsriddaAELKT-ILESIQRLKVkTASPELAIARLSGGNQQKAVLAKCLLLNPKILI 428
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 3999 LDEPTSGVDPCSRHSLWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVLQHGRLR 4053
Cdd:PRK13549  429 LDEPTRGIDVGAKYEIYKLINQLvQQGVAIIVISSELPEVLGLSDRVLVMHEGKLK 484
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
4707-4902 2.55e-10

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 66.57  E-value: 2.55e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGECFGLLGVNGAGKSTTFKML-------NGEVSLtSGHAI-IRTPMgDAVDlssAGTA---------GVL 4769
Cdd:PRK10762  268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLygalprtSGYVTL-DGHEVvTRSPQ-DGLA---NGIVyisedrkrdGLV 342
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4770 IGYCPQQD----ALDELLTGWehlyyyCSLRGIPRQcipEVAGDLIRRLHLEA-HADKPVATYSGGTKRKLSTALALVGK 4844
Cdd:PRK10762  343 LGMSVKENmsltALRYFSRAG------GSLKHADEQ---QAVSDFIRLFNIKTpSMEQAIGLLSGGNQQKVAIARGLMTR 413
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4845 PDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:PRK10762  414 PKVLILDEPTRGVDVGAKKEIYQLINQFKAEGLSIILVSSEMPEVLGMSDRILVMHEG 471
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
4712-4858 2.67e-10

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 66.90  E-value: 2.67e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4712 LGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAII--------------RTPMGDAVDLSSAGTAGV--------L 4769
Cdd:PRK11147   24 LHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYeqdlivarlqqdppRNVEGTVYDFVAEGIEEQaeylkryhD 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4770 IGYCPQQDALDELLTGWEHLyyycslrgiprQCIPEVAG---------DLIRRLHLEAhaDKPVATYSGGTKRKLSTALA 4840
Cdd:PRK11147  104 ISHLVETDPSEKNLNELAKL-----------QEQLDHHNlwqlenrinEVLAQLGLDP--DAALSSLSGGWLRKAALGRA 170
                         170
                  ....*....|....*...
gi 767944871 4841 LVGKPDILLLDEPSSGMD 4858
Cdd:PRK11147  171 LVSNPDVLLLDEPTNHLD 188
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
4701-4917 2.81e-10

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 66.75  E-value: 2.81e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4701 FQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNG--EVSLTSGHAIIRTPM------------------------ 4754
Cdd:TIGR03269   10 FDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGmdQYEPTSGRIIYHVALcekcgyverpskvgepcpvcggtl 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4755 ----GDAVDLSSAGTAGV-------------LIGycpQQDALDELLTGWEHLYYycslrgiPRQCIPEVAGDLIRRLHLE 4817
Cdd:TIGR03269   90 epeeVDFWNLSDKLRRRIrkriaimlqrtfaLYG---DDTVLDNVLEALEEIGY-------EGKEAVGRAVDLIEMVQLS 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4818 AHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRL 4896
Cdd:TIGR03269  160 HRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKAsGISMVLTSHWPEVIEDLSDKA 239
                          250       260
                   ....*....|....*....|.
gi 767944871  4897 AIMVNGSFKCLGSPQHIKNRF 4917
Cdd:TIGR03269  240 IWLENGEIKEEGTPDEVVAVF 260
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
4709-4902 2.84e-10

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 63.28  E-value: 2.84e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4709 DISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGVLIGYCPQQDALDELLTGWEH 4788
Cdd:cd03298    16 HFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLI-----NGVDVTAAPPADRPVSMLFQENNLFAHLTVEQN 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4789 LYYYCS----LRGIPRQCIPEVAGdlirRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRY 4864
Cdd:cd03298    91 VGLGLSpglkLTAEDRQAIEVALA----RVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAE 166
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 767944871 4865 LWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:cd03298   167 MLDLVLDLHAEtKMTVLMVTHQPEDAKRLAQRVVFLDNG 205
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
4706-4886 2.97e-10

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 63.66  E-value: 2.97e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGV--LIGYCPQQDAL---- 4779
Cdd:cd03252    17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLV-----DGHDLALADPAWLrrQVGVVLQENVLfnrs 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4780 --DELLTGWEhlyyycslrGIPRQCIPEVAG-----DLIRRLHL--EAHADKPVATYSGGTKRKLSTALALVGKPDILLL 4850
Cdd:cd03252    92 irDNIALADP---------GMSMERVIEAAKlagahDFISELPEgyDTIVGEQGAGLSGGQRQRIAIARALIHNPRILIF 162
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 767944871 4851 DEPSSGMDPCSKRYLWQTiMKEVREGCAAVLTSHSM 4886
Cdd:cd03252   163 DEATSALDYESEHAIMRN-MHDICAGRTVIIIAHRL 197
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
3863-4008 3.12e-10

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 63.33  E-value: 3.12e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3863 LTFYRDQITALL--GTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT-DLSRVRMELGVCP--QQDI-LLDNLtvreHL 3936
Cdd:PRK13543   30 LDFHVDAGEALLvqGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRgDRSRFMAYLGHLPglKADLsTLENL----HF 105
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 3937 LLFASIKAPQwtkkelhQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDP 4008
Cdd:PRK13543  106 LCGLHGRRAK-------QMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDL 170
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
4707-4884 3.34e-10

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 66.50  E-value: 3.34e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4707 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmGDAVDLssagtagvliGYCPQQ-DALDELLTG 4785
Cdd:TIGR03719  338 IDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI----GETVKL----------AYVDQSrDALDPNKTV 403
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4786 WEhlyyycslrgiprqcipEVAG--DLIR--------RLHLEAH----AD--KPVATYSGGTKRKLSTALALVGKPDILL 4849
Cdd:TIGR03719  404 WE-----------------EISGglDIIKlgkreipsRAYVGRFnfkgSDqqKKVGQLSGGERNRVHLAKTLKSGGNVLL 466
                          170       180       190
                   ....*....|....*....|....*....|....*
gi 767944871  4850 LDEPSSGMDPCSKRYLWQTImkEVREGCAAVLtSH 4884
Cdd:TIGR03719  467 LDEPTNDLDVETLRALEEAL--LNFAGCAVVI-SH 498
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
3857-4058 3.37e-10

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 63.20  E-value: 3.37e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3857 VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT-DLSRVRMELGVCPQQDILLDNlTVREH 3935
Cdd:cd03369    23 VLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTiPLEDLRSSLTIIPQDPTLFSG-TIRSN 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3936 LLLFAsikapQWTKKELHQQVNQTLQDVDLTQHQhkqtralsgglKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLW 4015
Cdd:cd03369   102 LDPFD-----EYSDEEIYGALRVSEGGLNLSQGQ-----------RQLLCLARALLKRPRVLVLDEATASIDYATDALIQ 165
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 767944871 4016 DILLKYREGRTIIFTTHHLdEAEALSDRVAVLQHGRLRCCGPP 4058
Cdd:cd03369   166 KTIREEFTNSTILTIAHRL-RTIIDYDKILVMDAGEVKEYDHP 207
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
3858-4052 5.98e-10

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 65.58  E-value: 5.98e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3858 VQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL--QTDLSRVRMELGVCPQ---QDILLDNLTV 3932
Cdd:PRK09700  279 VRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDIspRSPLDAVKKGMAYITEsrrDNGFFPNFSI 358
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3933 REHLLLFASIKAPQW-------TKKELHQQVNQTLQDVDLTQHQHKQT-RALSGGLKRKLSLGIAFMGMSRTVVLDEPTS 4004
Cdd:PRK09700  359 AQNMAISRSLKDGGYkgamglfHEVDEQRTAENQRELLALKCHSVNQNiTELSGGNQQKVLISKWLCCCPEVIIFDEPTR 438
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 767944871 4005 GVDPCSRHSLWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:PRK09700  439 GIDVGAKAEIYKVMRQLaDDGKVILMVSSELPEIITVCDRIAVFCEGRL 487
cbiO PRK13640
energy-coupling factor transporter ATPase;
4706-4913 9.01e-10

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 63.28  E-value: 9.01e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNG---------------EVSLTSGHAI-IRTPMGDAVDLSSAGTAGVL 4769
Cdd:PRK13640   22 ALNDISFSIPRGSWTALIGHNGSGKSTISKLINGlllpddnpnskitvdGITLTAKTVWdIREKVGIVFQNPDNQFVGAT 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4770 IGycpqqdalDELLTGWEHlyyycslRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILL 4849
Cdd:PRK13640  102 VG--------DDVAFGLEN-------RAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIII 166
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4850 LDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLT-SHSMEECEaLCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:PRK13640  167 LDESTSMLDPAGKEQILKLIRKLKKKNNLTVISiTHDIDEAN-MADQVLVLDDGKLLAQGSPVEI 230
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
4688-4885 9.15e-10

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 65.07  E-value: 9.15e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4688 LVLYNLSKHYRrffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAG 4767
Cdd:TIGR02868  335 LELRDLSAGYP---GAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTL-----DGVPVSSLDQDE 406
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4768 V--LIGYCPQqDAldelltgweHLYYyCSLRGIPRQCIPEVAGD----LIRRLHLEAH-------ADKPV----ATYSGG 4830
Cdd:TIGR02868  407 VrrRVSVCAQ-DA---------HLFD-TTVRENLRLARPDATDEelwaALERVGLADWlralpdgLDTVLgeggARLSGG 475
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 767944871  4831 TKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKeVREGCAAVLTSHS 4885
Cdd:TIGR02868  476 ERQRLALARALLADAPILLLDEPTEHLDAETADELLEDLLA-ALSGRTVVLITHH 529
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
4707-4917 9.53e-10

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 65.15  E-value: 9.53e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHaiIRTpmgDAVDLS--SAGTAGVLIGYCPQQDaldELLT 4784
Cdd:COG4618   348 LRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGS--VRL---DGADLSqwDREELGRHIGYLPQDV---ELFD 419
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4785 GwehlyyycSLR-GIPR--QCIPE-------VAG--DLIRRL------HLEAHAdkpvATYSGGTKRKLSTALALVGKPD 4846
Cdd:COG4618   420 G--------TIAeNIARfgDADPEkvvaaakLAGvhEMILRLpdgydtRIGEGG----ARLSGGQRQRIGLARALYGDPR 487
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4847 ILLLDEPSSGMDPCSKRYLWQTI--MKEvrEGCAAVLTSHSMeecEAL--CTRLAIMVNGSFKCLGSPQHIKNRF 4917
Cdd:COG4618   488 LVVLDEPNSNLDDEGEAALAAAIraLKA--RGATVVVITHRP---SLLaaVDKLLVLRDGRVQAFGPRDEVLARL 557
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
4708-4885 1.03e-09

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 61.43  E-value: 1.03e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4708 QDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTAGVLIGYcpqQDALDELLTGWE 4787
Cdd:PRK13539   19 SGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLD---GGDIDDPDVAEACHYLGH---RNAMKPALTVAE 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4788 HLYYYCSLRGIPRQCIPEVagdlIRRLHLEAHADKPVATYSGGTKRKLSTA-LALVGKPdILLLDEPSSGMDPCSKRYLW 4866
Cdd:PRK13539   93 NLEFWAAFLGGEELDIAAA----LEAVGLAPLAHLPFGYLSAGQKRRVALArLLVSNRP-IWILDEPTAALDAAAVALFA 167
                         170
                  ....*....|....*....
gi 767944871 4867 QTIMKEVREGCAAVLTSHS 4885
Cdd:PRK13539  168 ELIRAHLAQGGIVIAATHI 186
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
4714-4858 1.08e-09

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 62.43  E-value: 1.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4714 IPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGhaiirtpmgdavdlsSAGTAGVLIGYCPQQDALDELLTGWEHLYYYC 4793
Cdd:cd03237    22 ISESEVIGILGPNGIGKTTFIKMLAGVLKPDEG---------------DIEIELDTVSYKPQYIKADYEGTVRDLLSSIT 86
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4794 SLRGIPRQCIPEVagdlIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMD 4858
Cdd:cd03237    87 KDFYTHPYFKTEI----AKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLD 147
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
3852-4057 1.32e-09

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 62.41  E-value: 1.32e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3852 EGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPP----TSGTIIINGKNLQTDLSRVRMELGVcpqqdilL 3927
Cdd:PRK10418   13 QAAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPAgvrqTAGRVLLDGKPVAPCALRGRKIATI-------M 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3928 DN--------LTVREHLL--LFASIKAPQwtkkelHQQVNQTLQDVDLTQHQhkqtRAL-------SGGLKRKLSLGIAF 3990
Cdd:PRK10418   86 QNprsafnplHTMHTHARetCLALGKPAD------DATLTAALEAVGLENAA----RVLklypfemSGGMLQRMMIALAL 155
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 3991 MGMSRTVVLDEPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGRLRCCGP 4057
Cdd:PRK10418  156 LCEAPFIIADEPTTDLDVVAQARILDLLesIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGD 224
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
4701-4893 1.32e-09

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 64.18  E-value: 1.32e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4701 FQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNG--EVSLTSGHAIIRTPMGDAVDLSSAGTAGVLIGYcpQQDA 4778
Cdd:PRK13549   15 FGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGvyPHGTYEGEIIFEGEELQASNIRDTERAGIAIIH--QELA 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4779 LDELLTGWEHLYYYCSLRGIPRQCIPEV---AGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSS 4855
Cdd:PRK13549   93 LVKELSVLENIFLGNEITPGGIMDYDAMylrAQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKALNKQARLLILDEPTA 172
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 767944871 4856 GMDPCSKRYLWqTIMKEVRE-GCAAVLTSHSMEECEALC 4893
Cdd:PRK13549  173 SLTESETAVLL-DIIRDLKAhGIACIYISHKLNEVKAIS 210
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
3853-4050 1.65e-09

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 63.96  E-value: 1.65e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTiismlTGLH----PPTSGTIIINGKNLQTdLSR-----VRMELGVCPQ- 3922
Cdd:PRK15134  297 DHNVVVKNISFTLRPGETLGLVGESGSGKST-----TGLAllrlINSQGEIWFDGQPLHN-LNRrqllpVRHRIQVVFQd 370
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3923 -----------QDILLDNLTVREhlllfasikaPQWTKKELHQQVNQTLQDVDL-TQHQHKQTRALSGGLKRKLSLGIAF 3990
Cdd:PRK15134  371 pnsslnprlnvLQIIEEGLRVHQ----------PTLSAAQREQQVIAVMEEVGLdPETRHRYPAEFSGGQRQRIAIARAL 440
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 3991 MGMSRTVVLDEPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHG 4050
Cdd:PRK15134  441 ILKPSLIILDEPTSSLDKTVQAQILALLksLQQKHQLAYLFISHDLHVVRALCHQVIVLRQG 502
cbiO PRK13646
energy-coupling factor transporter ATPase;
4706-4926 1.86e-09

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 62.10  E-value: 1.86e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHA-----IIRTPMGDAVDLSSAGTAGVLIGYCPQQ---D 4777
Cdd:PRK13646   22 AIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVtvddiTITHKTKDKYIRPVRKRIGMVFQFPESQlfeD 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4778 ALD-ELLTGWEHLyyycslrGIPRQCIPEVAGDLIRRLHLEAHA-DKPVATYSGGTKRKLSTALALVGKPDILLLDEPSS 4855
Cdd:PRK13646  102 TVErEIIFGPKNF-------KMNLDEVKNYAHRLLMDLGFSRDVmSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTA 174
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4856 GMDPCSKRYLWQTIMK-EVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPqhiKNRFGDGYTVKVW 4926
Cdd:PRK13646  175 GLDPQSKRQVMRLLKSlQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSP---KELFKDKKKLADW 243
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
4708-4902 1.95e-09

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 63.78  E-value: 1.95e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4708 QDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAG---TAGVLIgyCPQ---QDALDE 4781
Cdd:PRK11288  270 EPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLD---GKPIDIRSPRdaiRAGIML--CPEdrkAEGIIP 344
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4782 LLTGWEHLYYYCSLRGIPRQCI------PEVAGDLIRRLHLE-AHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPS 4854
Cdd:PRK11288  345 VHSVADNINISARRHHLRAGCLinnrweAENADRFIRSLNIKtPSREQLIMNLSGGNQQKAILGRWLSEDMKVILLDEPT 424
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 767944871 4855 SGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:PRK11288  425 RGIDVGAKHEIYNVIYELAAQGVAVLFVSSDLPEVLGVADRIVVMREG 472
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
3842-4058 2.00e-09

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 63.67  E-value: 2.00e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3842 VTLVSVTKEYEGhKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGL--HPPTSGTIIIN----------------- 3902
Cdd:TIGR03269    1 IEVKNLTKKFDG-KEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMdqYEPTSGRIIYHvalcekcgyverpskvg 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3903 ------GKNLQT------DLS-----RVRMELGVCPQQDI-LLDNLTVREHLllfasIKAPQWTKKELHQQVNQTLQDVD 3964
Cdd:TIGR03269   80 epcpvcGGTLEPeevdfwNLSdklrrRIRKRIAIMLQRTFaLYGDDTVLDNV-----LEALEEIGYEGKEAVGRAVDLIE 154
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3965 LTQHQHKQT---RALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLK--YREGRTIIFTTHHLDEAEA 4039
Cdd:TIGR03269  155 MVQLSHRIThiaRDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEavKASGISMVLTSHWPEVIED 234
                          250
                   ....*....|....*....
gi 767944871  4040 LSDRVAVLQHGRLRCCGPP 4058
Cdd:TIGR03269  235 LSDKAIWLENGEIKEEGTP 253
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
4706-4887 2.03e-09

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 63.84  E-value: 2.03e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGVL--IGYCPQQDALdell 4783
Cdd:TIGR02857  337 ALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAV-----NGVPLADADADSWRdqIAWVPQHPFL---- 407
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4784 tgwehlyYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVAT---------------YSGGTKRKLSTALALVGKPDIL 4848
Cdd:TIGR02857  408 -------FAGTIAENIRLARPDASDAEIREALERAGLDEFVAAlpqgldtpigeggagLSGGQAQRLALARAFLRDAPLL 480
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 767944871  4849 LLDEPSSGMDPCSKrylwQTIMKEVRE---GCAAVLTSHSME 4887
Cdd:TIGR02857  481 LLDEPTAHLDAETE----AEVLEALRAlaqGRTVLLVTHRLA 518
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
4698-4884 2.03e-09

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 60.59  E-value: 2.03e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4698 RRFFQNIiavqdiSLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTAGVLIgYCPQQD 4777
Cdd:PRK13538   14 RILFSGL------SFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQ---GEPIRRQRDEYHQDLL-YLGHQP 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4778 ALDELLTGWEHLYYYCSLRGIPRQcipEVAGDLIRRLHLEAHADKPVATYSGGTKRKlsTALA--LVGKPDILLLDEPSS 4855
Cdd:PRK13538   84 GIKTELTALENLRFYQRLHGPGDD---EALWEALAQVGLAGFEDVPVRQLSAGQQRR--VALArlWLTRAPLWILDEPFT 158
                         170       180
                  ....*....|....*....|....*....
gi 767944871 4856 GMDPCSKRYLWQTIMKEVREGCAAVLTSH 4884
Cdd:PRK13538  159 AIDKQGVARLEALLAQHAEQGGMVILTTH 187
cbiO PRK13641
energy-coupling factor transporter ATPase;
4709-4957 2.35e-09

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 62.15  E-value: 2.35e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4709 DISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIR----TPMGDAVDLSSAGTAGVLIGYCPQQDALDEllT 4784
Cdd:PRK13641   25 NISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAgyhiTPETGNKNLKKLRKKVSLVFQFPEAQLFEN--T 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4785 GWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHL-EAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKR 4863
Cdd:PRK13641  103 VLKDVEFGPKNFGFSEDEAKEKALKWLKKVGLsEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEGRK 182
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4864 YLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHIknrFGDgytvKVWLCKEANQHCTVSDHL-K 4942
Cdd:PRK13641  183 EMMQLFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEI---FSD----KEWLKKHYLDEPATSRFAsK 255
                         250
                  ....*....|....*
gi 767944871 4943 LYFPGIQFKGQHLNL 4957
Cdd:PRK13641  256 LEKGGFKFSEMPLTI 270
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
3857-4051 2.48e-09

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 60.91  E-value: 2.48e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3857 VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRvrmelgvCPQQDILldnlTVREHL 3936
Cdd:COG4778    26 VLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDGGWVDLAQ-------ASPREIL----ALRRRT 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3937 LLFAS-----IkaPQWTKKELhqqVNQTLQDVDLTQHQ-HKQTRAL------------------SGGLKRKLSLGIAFMG 3992
Cdd:COG4778    95 IGYVSqflrvI--PRVSALDV---VAEPLLERGVDREEaRARARELlarlnlperlwdlppatfSGGEQQRVNIARGFIA 169
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3993 MSRTVVLDEPTSGVDPCSRHSLWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVLQHGR 4051
Cdd:COG4778   170 DPPLLLLDEPTASLDAANRAVVVELIEEAkARGTAIIGIFHDEEVREAVADRVVDVTPFS 229
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
4709-4902 3.03e-09

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 63.15  E-value: 3.03e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4709 DISLGIPKGECFGLLGVNGAGKSTTFKMLNGevsltsghaiIRTPMGDAV-----DLSSAGTAGVL---IGYCP---QQD 4777
Cdd:PRK15439  281 NISLEVRAGEILGLAGVVGAGRTELAETLYG----------LRPARGGRImlngkEINALSTAQRLargLVYLPedrQSS 350
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4778 AL--DELLTgWEHLYYYCSLRGIPRQCIPEVAgdLIRRLHLE-----AHADKPVATYSGGTKRKLSTALALVGKPDILLL 4850
Cdd:PRK15439  351 GLylDAPLA-WNVCALTHNRRGFWIKPARENA--VLERYRRAlnikfNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIV 427
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4851 DEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:PRK15439  428 DEPTRGVDVSARNDIYQLIRSIAAQNVAVLFISSDLEEIEQMADRVLVMHQG 479
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
4705-4913 3.09e-09

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 61.57  E-value: 3.09e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4705 IAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmGDAVdlSSAGT-----------AGVLIGYc 4773
Cdd:PRK13634   21 RALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTI----GERV--ITAGKknkklkplrkkVGIVFQF- 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4774 PQQDALDEllTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHL-EAHADKPVATYSGGTKRKLSTALALVGKPDILLLDE 4852
Cdd:PRK13634   94 PEHQLFEE--TVEKDICFGPMNFGVSEEDAKQKAREMIELVGLpEELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDE 171
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4853 PSSGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:PRK13634  172 PTAGLDPKGRKEMMEMFYKLHKEkGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREI 233
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
3838-4051 3.41e-09

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 61.10  E-value: 3.41e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3838 SAPGVTLVSVTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKN-LQTDLSR---- 3912
Cdd:PRK11701    3 DQPLLSVRGLTKLY-GPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDgQLRDLYAlsea 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3913 -----VRMELGVCPQQDilLDNL--------TVREHLLL-----FASI--KAPQWtkkelhqqvnqtLQDVDLTQHQ-HK 3971
Cdd:PRK11701   82 errrlLRTEWGFVHQHP--RDGLrmqvsaggNIGERLMAvgarhYGDIraTAGDW------------LERVEIDAARiDD 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3972 QTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQH 4049
Cdd:PRK11701  148 LPTTFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLrgLVRELGLAVVIVTHDLAVARLLAHRLLVMKQ 227

                  ..
gi 767944871 4050 GR 4051
Cdd:PRK11701  228 GR 229
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
4708-4903 3.83e-09

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 59.79  E-value: 3.83e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4708 QDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHaiirtpmgdavdLSSAGTagvlIGYCPQQDAL------DE 4781
Cdd:cd03250    22 KDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGS------------VSVPGS----IAYVSQEPWIqngtirEN 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4782 LLTG--WEHLYYYCSLRgiprqcipevAGDLIRRLHLEAHADKPV-----ATYSGGTKRKLSTALALVGKPDILLLDEPS 4854
Cdd:cd03250    86 ILFGkpFDEERYEKVIK----------ACALEPDLEILPDGDLTEigekgINLSGGQKQRISLARAVYSDADIYLLDDPL 155
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 767944871 4855 SGMDPCSKRYLWQT-IMKEVREGCAAVLTSHSMEECEAlCTRLAIMVNGS 4903
Cdd:cd03250   156 SAVDAHVGRHIFENcILGLLLNNKTRILVTHQLQLLPH-ADQIVVLDNGR 204
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
4698-4885 4.08e-09

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 60.63  E-value: 4.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4698 RRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLN------------GEVSLTSGHaiIRTPMGDAVDLSSAgt 4765
Cdd:PRK14267   11 RVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNrllelneearveGEVRLFGRN--IYSPDVDPIEVRRE-- 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4766 agvlIGYCPQQDALDELLTGWEHLYYYCSLRGI--PRQCIPEVAGDLIRRLHL-----EAHADKPvATYSGGTKRKLSTA 4838
Cdd:PRK14267   87 ----VGMVFQYPNPFPHLTIYDNVAIGVKLNGLvkSKKELDERVEWALKKAALwdevkDRLNDYP-SNLSGGQRQRLVIA 161
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 767944871 4839 LALVGKPDILLLDEPSSGMDPCSKRYLwQTIMKEVREGCAAVLTSHS 4885
Cdd:PRK14267  162 RALAMKPKILLMDEPTANIDPVGTAKI-EELLFELKKEYTIVLVTHS 207
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
3854-4052 4.22e-09

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 62.81  E-value: 4.22e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3854 HKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL-QTDLSRVRMELGVCPQQDILLDNlTV 3932
Cdd:PRK10789  327 DHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLtKLQLDSWRSRLAVVSQTPFLFSD-TV 405
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3933 REHLLLfasiKAPQWTKKELHQQVN-QTLQDVDLTQHQHKQTRA------LSGGLKRKLSLGIAFMGMSRTVVLDEPTSG 4005
Cdd:PRK10789  406 ANNIAL----GRPDATQQEIEHVARlASVHDDILRLPQGYDTEVgergvmLSGGQKQRISIARALLLNAEILILDDALSA 481
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 767944871 4006 VDPCSRHSLWDILLKYREGRTIIFTTHHLdEAEALSDRVAVLQHGRL 4052
Cdd:PRK10789  482 VDGRTEHQILHNLRQWGEGRTVIISAHRL-SALTEASEILVMQHGHI 527
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
4675-4858 4.97e-09

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 62.88  E-value: 4.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4675 EKRVFEGRTNGDILVLY-NLSKHYRRFfqniiaVQDISLG-IPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGhaiirt 4752
Cdd:COG1245   328 EVHAPRREKEEETLVEYpDLTKSYGGF------SLEVEGGeIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEG------ 395
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4753 pmgdAVDLssagtaGVLIGYCPQ----------QDALDELLTG-WEHLYYYcslrgiprqcipevaGDLIRRLHLEAHAD 4821
Cdd:COG1245   396 ----EVDE------DLKISYKPQyispdydgtvEEFLRSANTDdFGSSYYK---------------TEIIKPLGLEKLLD 450
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 767944871 4822 KPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMD 4858
Cdd:COG1245   451 KNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLD 487
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
4707-4891 6.18e-09

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 59.42  E-value: 6.18e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSL---TSGHAIIrtpmgDAVDLSSAGTAGVLIGYCPQQDALDELL 4783
Cdd:COG4136    17 LAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPafsASGEVLL-----NGRRLTALPAEQRRIGILFQDDLLFPHL 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4784 TGWEHLYYycSL-RGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSK 4862
Cdd:COG4136    92 SVGENLAF--ALpPTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLDAALR 169
                         170       180       190
                  ....*....|....*....|....*....|
gi 767944871 4863 RYLWQTIMKEVRE-GCAAVLTSHSMEECEA 4891
Cdd:COG4136   170 AQFREFVFEQIRQrGIPALLVTHDEEDAPA 199
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
4688-4905 7.71e-09

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 58.48  E-value: 7.71e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYRRffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTA- 4766
Cdd:cd03247     1 LSINNVSFSYPE--QEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITL-----DGVPVSDLEKAl 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4767 GVLIGYCPQQDALdelltgwehlyYYCSLRGiprqcipevagDLIRRLhleahadkpvatySGGTKRKLSTALALVGKPD 4846
Cdd:cd03247    74 SSLISVLNQRPYL-----------FDTTLRN-----------NLGRRF-------------SGGERQRLALARILLQDAP 118
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4847 ILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSH--SMEECEALCtrlaIMVNGSFK 4905
Cdd:cd03247   119 IVLLDEPTVGLDPITERQLLSLIFEVLKDKTLIWITHHltGIEHMDKIL----FLENGKII 175
GguA NF040905
sugar ABC transporter ATP-binding protein;
3846-4051 7.98e-09

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 61.73  E-value: 7.98e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3846 SVTKEYEGHKAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTS--GTIIINGKNLQ-TDLSR--------VR 3914
Cdd:NF040905    6 GITKTFPGVKAL-DDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHGSyeGEILFDGEVCRfKDIRDsealgiviIH 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3915 MELGVCPQqdilldnLTVREHLLL---FASIKAPQWtkKELHQQVNQTLQDVDLtqHQHKQTRALSGGL-KRKLsLGIAf 3990
Cdd:NF040905   85 QELALIPY-------LSIAENIFLgneRAKRGVIDW--NETNRRARELLAKVGL--DESPDTLVTDIGVgKQQL-VEIA- 151
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 3991 MGMSRTV---VLDEPTSGV-DPCSRHsLWDILLKYRE-GRTIIFTTHHLDEAEALSDRVAVLQHGR 4051
Cdd:NF040905  152 KALSKDVkllILDEPTAALnEEDSAA-LLDLLLELKAqGITSIIISHKLNEIRRVADSITVLRDGR 216
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
3870-4082 8.40e-09

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 61.04  E-value: 8.40e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3870 ITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqtdlsrVRMELGVC--PQ--------QDI-LLDNLTVREHLLL 3938
Cdd:PRK11144   26 ITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVL------FDAEKGIClpPEkrrigyvfQDArLFPHYKVRGNLRY 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3939 fasikapqWTKKELHQQVNQTlqdVDLTQHQHKQTR---ALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVD-PCSRHsl 4014
Cdd:PRK11144  100 --------GMAKSMVAQFDKI---VALLGIEPLLDRypgSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDlPRKRE-- 166
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4015 wdiLLKY-----REGRT-IIFTTHHLDEAEALSDRVAVLQHGRLRCCGPpfcLKEAYG-QGLR--LTLTRQPSVLEA 4082
Cdd:PRK11144  167 ---LLPYlerlaREINIpILYVSHSLDEILRLADRVVVLEQGKVKAFGP---LEEVWAsSAMRpwLPKEEQSSILKV 237
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
4707-4910 9.15e-09

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 58.69  E-value: 9.15e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNG--EVSLTSGHaiIRTPMGDAVDLSsagtagvligycPQQDALDELLT 4784
Cdd:cd03217    16 LKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGhpKYEVTEGE--ILFKGEDITDLP------------PEERARLGIFL 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4785 GWEHlyyycslrgiPrqciPEVAG----DLIRRLHleahadkpvATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPC 4860
Cdd:cd03217    82 AFQY----------P----PEIPGvknaDFLRYVN---------EGFSGGEKKRNEILQLLLLEPDLAILDEPDSGLDID 138
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4861 SKRYLWQTIMKEVREGCAAVLTSHSMEECEAL-CTRLAIMVNGSFKCLGSP 4910
Cdd:cd03217   139 ALRLVAEVINKLREEGKSVLIITHYQRLLDYIkPDRVHVLYDGRIVKSGDK 189
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
3852-4066 1.05e-08

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 62.27  E-value: 1.05e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3852 EGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNL-QTDLSRVRMELGVCPQQDILLDNl 3930
Cdd:TIGR00957 1296 EDLDLVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIaKIGLHDLRFKITIIPQDPVLFSG- 1374
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3931 TVREHLLLFASIKAPQ-WTKKEL-HQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDP 4008
Cdd:TIGR00957 1375 SLRMNLDPFSQYSDEEvWWALELaHLKTFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDL 1454
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871  4009 CSRHSLWDILLKYREGRTIIFTTHHLDEAEALSdRVAVLQHGRLRCCGPPFCLKEAYG 4066
Cdd:TIGR00957 1455 ETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYT-RVIVLDKGEVAEFGAPSNLLQQRG 1511
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
3857-4033 1.09e-08

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 58.42  E-value: 1.09e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3857 VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCPQQDILLDNLTVREHL 3936
Cdd:PRK13540   16 LLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKKDLCTYQKQLCFVGHRSGINPYLTLRENC 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3937 LLfasikapqwtkkELH-----QQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSR 4011
Cdd:PRK13540   96 LY------------DIHfspgaVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSL 163
                         170       180
                  ....*....|....*....|...
gi 767944871 4012 HSLWDILLKYR-EGRTIIFTTHH 4033
Cdd:PRK13540  164 LTIITKIQEHRaKGGAVLLTSHQ 186
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
4706-4902 1.55e-08

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 60.81  E-value: 1.55e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGVL---IGYCP---QQDAL 4779
Cdd:COG3845   273 ALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRL-----DGEDITGLSPRERRrlgVAYIPedrLGRGL 347
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4780 DELLTGWEHLyyycSLRGIPRQciPEVAGDLIRRLHLEAHADK--------------PVATYSGGTKRKLSTALALVGKP 4845
Cdd:COG3845   348 VPDMSVAENL----ILGRYRRP--PFSRGGFLDRKAIRAFAEElieefdvrtpgpdtPARSLSGGNQQKVILARELSRDP 421
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4846 DILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:COG3845   422 KLLIAAQPTRGLDVGAIEFIHQRLLELRDAGAAVLLISEDLDEILALSDRIAVMYEG 478
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
4692-4902 1.77e-08

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 58.93  E-value: 1.77e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYR-----RFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIR-TPMGDavdLSSAGT 4765
Cdd:PRK10419    8 GLSHHYAhgglsGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRgEPLAK---LNRAQR 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4766 AG-------VLigycpqQDALDEL----LTGW---EHLYYYCSLRGIPRQcipEVAGDLIRRLHL-EAHADKPVATYSGG 4830
Cdd:PRK10419   85 KAfrrdiqmVF------QDSISAVnprkTVREiirEPLRHLLSLDKAERL---ARASEMLRAVDLdDSVLDKRPPQLSGG 155
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4831 TKRKLSTALALVGKPDILLLDEPSSGMDpcskRYLWQTI---MKEVRE--GCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:PRK10419  156 QLQRVCLARALAVEPKLLILDEAVSNLD----LVLQAGVirlLKKLQQqfGTACLFITHDLRLVERFCQRVMVMDNG 228
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
4707-4888 2.40e-08

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 57.80  E-value: 2.40e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGEcFGLL-GVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmGDAVDLSSAGTAGVLIGYCPQQDAL------ 4779
Cdd:PRK10247   23 LNNISFSLRAGE-FKLItGPSGCGKSTLLKIVASLISPTSGTLLFE---GEDISTLKPEIYRQQVSYCAQTPTLfgdtvy 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4780 DELLTGWEhlyyycsLRGIPRQciPEVAGDLIRRLHLEAHA-DKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMD 4858
Cdd:PRK10247   99 DNLIFPWQ-------IRNQQPD--PAIFLDDLERFALPDTIlTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITSALD 169
                         170       180       190
                  ....*....|....*....|....*....|.
gi 767944871 4859 PCSKRYLWQTIMKEVREGCAAVL-TSHSMEE 4888
Cdd:PRK10247  170 ESNKHNVNEIIHRYVREQNIAVLwVTHDKDE 200
PLN03073 PLN03073
ABC transporter F family; Provisional
4704-4858 2.45e-08

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 60.64  E-value: 2.45e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4704 IIAVQDISLGIPKGEC------FGL--------LGVNGAGKSTTFKMLNGEVSLTSGhAIIRTPMgdavdlssagtagVL 4769
Cdd:PLN03073  508 IISFSDASFGYPGGPLlfknlnFGIdldsriamVGPNGIGKSTILKLISGELQPSSG-TVFRSAK-------------VR 573
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4770 IGYCPQQ--DALDelLTGWEHLYYYCSLRGIPRQCIpevagdlirRLHLEAH------ADKPVATYSGGTKRKLSTALAL 4841
Cdd:PLN03073  574 MAVFSQHhvDGLD--LSSNPLLYMMRCFPGVPEQKL---------RAHLGSFgvtgnlALQPMYTLSGGQKSRVAFAKIT 642
                         170
                  ....*....|....*..
gi 767944871 4842 VGKPDILLLDEPSSGMD 4858
Cdd:PLN03073  643 FKKPHILLLDEPSNHLD 659
cbiO PRK13649
energy-coupling factor transporter ATPase;
4706-4913 3.31e-08

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 58.22  E-value: 3.31e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIR----TPMGDAVDLSSAGTAGVLIGYCPQQDALDE 4781
Cdd:PRK13649   22 ALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDdtliTSTSKNKDIKQIRKKVGLVFQFPESQLFEE 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4782 llTGWEHLYYYCSLRGIPrqciPEVAGDLIR-RLHL----EAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSG 4856
Cdd:PRK13649  102 --TVLKDVAFGPQNFGVS----QEEAEALAReKLALvgisESLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAG 175
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4857 MDPCSKRYLwQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:PRK13649  176 LDPKGRKEL-MTLFKKLHQsGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDI 232
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
4709-4853 3.97e-08

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 59.75  E-value: 3.97e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4709 DISLGIPKGECFGLLGVNGAGKSTTFKMLNGevsltsghaiirtpmgdaVDLSSAGTA----GVLIGYCPQQDALDELLT 4784
Cdd:PRK11819   25 DISLSFFPGAKIGVLGLNGAGKSTLLRIMAG------------------VDKEFEGEArpapGIKVGYLPQEPQLDPEKT 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4785 gwehlyyycsLRGIPRQCIPEV---------------------------------------AGDLIRRLHLEAHA----- 4820
Cdd:PRK11819   87 ----------VRENVEEGVAEVkaaldrfneiyaayaepdadfdalaaeqgelqeiidaadAWDLDSQLEIAMDAlrcpp 156
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 767944871 4821 -DKPVATYSGGTKRKLstALA--LVGKPDILLLDEP 4853
Cdd:PRK11819  157 wDAKVTKLSGGERRRV--ALCrlLLEKPDMLLLDEP 190
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
4707-4905 4.09e-08

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 59.56  E-value: 4.09e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGECFGLLGVNGAGKSTTFKML--------NGEVSLTSGHAIIRTPMgDAVDlssAGTAGV-----LIGYC 4773
Cdd:PRK13549  278 VDDVSFSLRRGEILGIAGLVGAGRTELVQCLfgaypgrwEGEIFIDGKPVKIRNPQ-QAIA---QGIAMVpedrkRDGIV 353
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4774 PQQD--------ALDELlTGWEHLYYYCSLRGIPRQcipevagdlIRRLHLE-AHADKPVATYSGGTKRKLSTALALVGK 4844
Cdd:PRK13549  354 PVMGvgknitlaALDRF-TGGSRIDDAAELKTILES---------IQRLKVKtASPELAIARLSGGNQQKAVLAKCLLLN 423
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4845 PDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFK 4905
Cdd:PRK13549  424 PKILILDEPTRGIDVGAKYEIYKLINQLVQQGVAIIVISSELPEVLGLSDRVLVMHEGKLK 484
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
3842-4035 4.13e-08

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 60.31  E-value: 4.13e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3842 VTLVSVTKEY-EGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLhPPTSGTIIINGKNLQT-DLSRVRMELGV 3919
Cdd:TIGR01271 1218 MDVQGLTAKYtEAGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRL-LSTEGEIQIDGVSWNSvTLQTWRKAFGV 1296
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3920 CPQQDILLDNlTVREHLLLFAsikapQWTKKELHQQVNQTLQDVDLTQHQHKQT-------RALSGGLKRKLSLGIAFMG 3992
Cdd:TIGR01271 1297 IPQKVFIFSG-TFRKNLDPYE-----QWSDEEIWKVAEEVGLKSVIEQFPDKLDfvlvdggYVLSNGHKQLMCLARSILS 1370
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 767944871  3993 MSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLD 4035
Cdd:TIGR01271 1371 KAKILLLDEPSAHLDPVTLQIIRKTLKQSFSNCTVILSEHRVE 1413
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
4692-4858 4.55e-08

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 59.36  E-value: 4.55e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHY--RrffqniIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmGDAVDLSsagtagvl 4769
Cdd:PRK11819  329 NLSKSFgdR------LLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI----GETVKLA-------- 390
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4770 igYCPQQ-DALDELLTGWEhlyyycslrgiprqcipEVAG--DLIR--------RLHLEAH----AD--KPVATYSGGTK 4832
Cdd:PRK11819  391 --YVDQSrDALDPNKTVWE-----------------EISGglDIIKvgnreipsRAYVGRFnfkgGDqqKKVGVLSGGER 451
                         170       180
                  ....*....|....*....|....*.
gi 767944871 4833 RKLSTALALVGKPDILLLDEPSSGMD 4858
Cdd:PRK11819  452 NRLHLAKTLKQGGNVLLLDEPTNDLD 477
PLN03140 PLN03140
ABC transporter G family member; Provisional
3870-4057 5.68e-08

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 59.86  E-value: 5.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3870 ITALLGTNGAGKTTIISMLTGLHPP--TSGTIIING--KNLQTdLSRVRmelGVCPQQDILLDNLTVREHLLLFASIKAP 3945
Cdd:PLN03140  908 LTALMGVSGAGKTTLMDVLAGRKTGgyIEGDIRISGfpKKQET-FARIS---GYCEQNDIHSPQVTVRESLIYSAFLRLP 983
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3946 -QWTKKELHQQVNQTLQDVDLTQHQHK-----QTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDpcSRHSLwdILL 4019
Cdd:PLN03140  984 kEVSKEEKMMFVDEVMELVELDNLKDAivglpGVTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLD--ARAAA--IVM 1059
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 767944871 4020 K-----YREGRTIIFTTHH--LDEAEALSDRVAVLQHGRLRCCGP 4057
Cdd:PLN03140 1060 RtvrntVDTGRTVVCTIHQpsIDIFEAFDELLLMKRGGQVIYSGP 1104
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
3852-4050 6.07e-08

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 56.51  E-value: 6.07e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3852 EGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSgtiiingknlqtDLSRVRMELGVCPQQDILLDnlt 3931
Cdd:COG2401    40 VVERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKGTP------------VAGCVDVPDNQFGREASLID--- 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3932 vreHLLLFASIKApqwtKKELHQQVNqtLQDVDLTQhqhKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDP--- 4008
Cdd:COG2401   105 ---AIGRKGDFKD----AVELLNAVG--LSDAVLWL---RRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRqta 172
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 767944871 4009 --CSR--HSLWDillkyREGRTIIFTTHHLDEAEALS-DRVAVLQHG 4050
Cdd:COG2401   173 krVARnlQKLAR-----RAGITLVVATHHYDVIDDLQpDLLIFVGYG 214
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
3842-4032 6.17e-08

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 59.14  E-value: 6.17e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEYEGhKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNlqtdlsrvrmELGVCP 3921
Cdd:PRK15064  320 LEVENLTKGFDN-GPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWSENA----------NIGYYA 388
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3922 Q--QDILLDNLTVREHLllfasikaPQWTK-KELHQQVNQTLQDVDLTQHQ-HKQTRALSGGLKRKLSLGIAFMGMSRTV 3997
Cdd:PRK15064  389 QdhAYDFENDLTLFDWM--------SQWRQeGDDEQAVRGTLGRLLFSQDDiKKSVKVLSGGEKGRMLFGKLMMQKPNVL 460
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 767944871 3998 VLDEPTSGVDPCSRHSLWDILLKYrEGrTIIFTTH 4032
Cdd:PRK15064  461 VMDEPTNHMDMESIESLNMALEKY-EG-TLIFVSH 493
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
4683-4902 7.54e-08

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 56.99  E-value: 7.54e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4683 TNGDILVLYNLSKHYRrffQNIIaVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAII-RTPMGDAVDLS 4761
Cdd:PRK11247    8 NQGTPLLLNAVSKRYG---ERTV-LNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAgTAPLAEAREDT 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4762 SA--GTAGVLigycPQQDALDELLTGwehlyyycsLRGIPRqcipEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTAL 4839
Cdd:PRK11247   84 RLmfQDARLL----PWKKVIDNVGLG---------LKGQWR----DAALQALAAVGLADRANEWPAALSGGQKQRVALAR 146
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4840 ALVGKPDILLLDEPSSGMDPCSK-------RYLWQtimkevREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:PRK11247  147 ALIHRPGLLLLDEPLGALDALTRiemqdliESLWQ------QHGFTVLLVTHDVSEAVAMADRVLLIEEG 210
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
4692-4888 8.38e-08

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 57.10  E-value: 8.38e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRFfqniIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLN----------GEVSLTSGHAIIRTPMGDAVDLS 4761
Cdd:PRK14243   15 NLNVYYGSF----LAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNrlndlipgfrVEGKVTFHGKNLYAPDVDPVEVR 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4762 SagTAGVL--------------IGYCPQ----QDALDELLTgwehlyyycslRGIPRQCIPEVAGDLIRRLHLeahadkp 4823
Cdd:PRK14243   91 R--RIGMVfqkpnpfpksiydnIAYGARingyKGDMDELVE-----------RSLRQAALWDEVKDKLKQSGL------- 150
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 4824 vaTYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLwQTIMKEVREGCAAVLTSHSMEE 4888
Cdd:PRK14243  151 --SLSGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRI-EELMHELKEQYTIIIVTHNMQQ 212
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
3841-4051 8.54e-08

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 57.93  E-value: 8.54e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3841 GVTLVSVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKnlqtdlsRV-RMElgv 3919
Cdd:PRK11650    3 GLKLQAVRKSYDGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGR-------VVnELE--- 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3920 cP-QQDI--------LLDNLTVREHLllfA-SIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSlgia 3989
Cdd:PRK11650   73 -PaDRDIamvfqnyaLYPHMSVRENM---AyGLKIRGMPKAEIEERVAEAARILELEPLLDRKPRELSGGQRQRVA---- 144
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871 3990 fmgMSRTVV-------LDEPTSGVDPCSR-HSLWDIL-LKYREGRTIIFTTHhlDEAEA--LSDRVAVLQHGR 4051
Cdd:PRK11650  145 ---MGRAIVrepavflFDEPLSNLDAKLRvQMRLEIQrLHRRLKTTSLYVTH--DQVEAmtLADRVVVMNGGV 212
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
3830-4034 8.64e-08

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 59.27  E-value: 8.64e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3830 NREGELEGSAPGVTLVSVTK--------EYEGHKAV--VQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTI 3899
Cdd:PTZ00265  363 NRKPLVENNDDGKKLKDIKKiqfknvrfHYDTRKDVeiYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDI 442
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3900 IIN-GKNLQ-TDLSRVRMELGVCPQQDILLDNLTVREHLLLFASIKAPQWTKKELHQQVN-------------------- 3957
Cdd:PTZ00265  443 IINdSHNLKdINLKWWRSKIGVVSQDPLLFSNSIKNNIKYSLYSLKDLEALSNYYNEDGNdsqenknkrnscrakcagdl 522
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3958 -------------------QTLQDVDLTQHQHK--------------------QTRALSGGLKRKLSLGIAFMGMSRTVV 3998
Cdd:PTZ00265  523 ndmsnttdsneliemrknyQTIKDSEVVDVSKKvlihdfvsalpdkyetlvgsNASKLSGGQKQRISIARAIIRNPKILI 602
                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 767944871 3999 LDEPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHL 4034
Cdd:PTZ00265  603 LDEATSSLDNKSEYLVQKTInnLKGNENRITIIIAHRL 640
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
4717-4912 1.05e-07

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 58.52  E-value: 1.05e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4717 GECFGLLGVNGAGKST-----TFKMLNG-EVS---LTSGHAIIRTPMGdavdlssagtagVLIGYCPQQDALDELLTGWE 4787
Cdd:TIGR00955   51 GELLAVMGSSGAGKTTlmnalAFRSPKGvKGSgsvLLNGMPIDAKEMR------------AISAYVQQDDLFIPTLTVRE 118
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4788 HLYYYCSLRgIPRQCIPEV----AGDLIRRLHLEAHAD------KPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGM 4857
Cdd:TIGR00955  119 HLMFQAHLR-MPRRVTKKEkrerVDEVLQALGLRKCANtrigvpGRVKGLSGGERKRLAFASELLTDPPLLFCDEPTSGL 197
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871  4858 DPCSKRYLWQTIMKEVREGCAAVLTSH--SMEECEaLCTRLAIMVNGSFKCLGSPQH 4912
Cdd:TIGR00955  198 DSFMAYSVVQVLKGLAQKGKTIICTIHqpSSELFE-LFDKIILMAEGRVAYLGSPDQ 253
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
4688-4902 1.15e-07

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 55.92  E-value: 1.15e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYRRFFQNIiavqdiSLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTA- 4766
Cdd:COG3840     2 LRLDDLTYRYGDFPLRF------DLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILW-----NGQDLTALPPAe 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4767 -GVLIGYcpQQDALDELLTGWEHLYY----YCSLRGIPRQCIPEVAgdliRRLHLEAHADKPVATYSGGTKRKLSTALAL 4841
Cdd:COG3840    71 rPVSMLF--QENNLFPHLTVAQNIGLglrpGLKLTAEQRAQVEQAL----ERVGLAGLLDRLPGQLSGGQRQRVALARCL 144
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 4842 VGKPDILLLDEPSSGMDPCskryLWQTIMKEVREGCAA-----VLTSHSMEECEALCTRLAIMVNG 4902
Cdd:COG3840   145 VRKRPILLLDEPFSALDPA----LRQEMLDLVDELCRErgltvLMVTHDPEDAARIADRVLLVADG 206
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
4688-4858 1.43e-07

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 57.98  E-value: 1.43e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHY--RRFFQNIiavqdiSLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGhaiirtpmgdAVDLSSAGT 4765
Cdd:PRK15064  320 LEVENLTKGFdnGPLFKNL------NLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSG----------TVKWSENAN 383
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4766 agvlIGYCPQQDA----LDELLTGWEHLYyycslrGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTK-RKLSTALA 4840
Cdd:PRK15064  384 ----IGYYAQDHAydfeNDLTLFDWMSQW------RQEGDDEQAVRGTLGRLLFSQDDIKKSVKVLSGGEKgRMLFGKLM 453
                         170
                  ....*....|....*...
gi 767944871 4841 LvGKPDILLLDEPSSGMD 4858
Cdd:PRK15064  454 M-QKPNVLVMDEPTNHMD 470
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
3837-4051 1.50e-07

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 54.96  E-value: 1.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3837 GSAPGVTLVSVTKEYEGHKA-VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPT---SGTIIINGKNLQTDLSR 3912
Cdd:cd03233     1 ASTLSWRNISFTTGKGRSKIpILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYKEFAEK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3913 VRMELGVCPQQDILLDNLTVREhLLLFAsikapqwtkkeLHQQVNQTLqdvdltqhqhkqtRALSGGLKRKLSLGIAFMG 3992
Cdd:cd03233    81 YPGEIIYVSEEDVHFPTLTVRE-TLDFA-----------LRCKGNEFV-------------RGISGGERKRVSIAEALVS 135
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 3993 MSRTVVLDEPTSGVDPCSRHslwDILLKYRE-----GRTIIFTTHHL-DEAEALSDRVAVLQHGR 4051
Cdd:cd03233   136 RASVLCWDNSTRGLDSSTAL---EILKCIRTmadvlKTTTFVSLYQAsDEIYDLFDKVLVLYEGR 197
PLN03232 PLN03232
ABC transporter C family member; Provisional
3840-4053 2.00e-07

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 58.06  E-value: 2.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3840 PGVTLVSVTKEY-----EGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIIngknlqtdlsrVR 3914
Cdd:PLN03232  610 PGAPAISIKNGYfswdsKTSKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHAETSSVV-----------IR 678
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3915 MELGVCPQQDILLdNLTVREHLLlFASIKAPQWTKKELHQQVNQTLQDV----DLTQHQHKQTRaLSGGLKRKLSLGIAF 3990
Cdd:PLN03232  679 GSVAYVPQVSWIF-NATVRENIL-FGSDFESERYWRAIDVTALQHDLDLlpgrDLTEIGERGVN-ISGGQKQRVSMARAV 755
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 3991 MGMSRTVVLDEPTSGVDPCSRHSLWDILLKYR-EGRTIIFTTHHLdEAEALSDRVAVLQHGRLR 4053
Cdd:PLN03232  756 YSNSDIYIFDDPLSALDAHVAHQVFDSCMKDElKGKTRVLVTNQL-HFLPLMDRIILVSEGMIK 818
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
3847-3901 2.33e-07

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 57.25  E-value: 2.33e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 767944871  3847 VTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIII 3901
Cdd:TIGR03719  328 LTKAF-GDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI 381
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
3847-4052 4.04e-07

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 56.57  E-value: 4.04e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEG-HKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQT-DLSRVRMELGVCPQQd 3924
Cdd:PRK11176  347 VTFTYPGkEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDyTLASLRNQVALVSQN- 425
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3925 ILLDNLTVREHLllfASIKAPQWTKKELHQQ---------VNQTLQDVDLTQHQHKQTraLSGGLKRKLSLGIAFMGMSR 3995
Cdd:PRK11176  426 VHLFNDTIANNI---AYARTEQYSREQIEEAarmayamdfINKMDNGLDTVIGENGVL--LSGGQRQRIAIARALLRDSP 500
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 3996 TVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLDEAEAlSDRVAVLQHGRL 4052
Cdd:PRK11176  501 ILILDEATSALDTESERAIQAALDELQKNRTSLVIAHRLSTIEK-ADEILVVEDGEI 556
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
4687-4884 4.16e-07

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 56.66  E-value: 4.16e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGhaIIRTPMGDAVDLSSAGTA 4766
Cdd:PRK10535    4 LLELKDIRRSYPSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSG--TYRVAGQDVATLDADALA 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4767 GVL---IGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVG 4843
Cdd:PRK10535   82 QLRrehFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMN 161
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 767944871 4844 KPDILLLDEPSSGMDPCSKRYLwQTIMKEVRE-GCAAVLTSH 4884
Cdd:PRK10535  162 GGQVILADEPTGALDSHSGEEV-MAILHQLRDrGHTVIIVTH 202
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
4703-4858 4.52e-07

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 54.47  E-value: 4.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4703 NIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGV--LIGYCPQQDALd 4780
Cdd:cd03249    15 DVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILL-----DGVDIRDLNLRWLrsQIGLVSQEPVL- 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4781 elltgwehlyYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATY---------------SGGTKRKLSTALALVGKP 4845
Cdd:cd03249    89 ----------FDGTIAENIRYGKPDATDEEVEEAAKKANIHDFIMSLpdgydtlvgergsqlSGGQKQRIAIARALLRNP 158
                         170
                  ....*....|...
gi 767944871 4846 DILLLDEPSSGMD 4858
Cdd:cd03249   159 KILLLDEATSALD 171
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
4707-4902 4.92e-07

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 54.32  E-value: 4.92e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGECFGLLGVNGAGKSTT----FKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGVLIGYCPQ--QDALD 4780
Cdd:PRK10418   19 VHGVSLTLQRGRVLALVGGSGSGKSLTcaaaLGILPAGVRQTAGRVLL-----DGKPVAPCALRGRKIATIMQnpRSAFN 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4781 ELLTGWEHLYYYCSLRGIPR------QCIPEVAGDLIRRLhLEAHADKpvatYSGGTKRKLSTALALVGKPDILLLDEPS 4854
Cdd:PRK10418   94 PLHTMHTHARETCLALGKPAddatltAALEAVGLENAARV-LKLYPFE----MSGGMLQRMMIALALLCEAPFIIADEPT 168
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 767944871 4855 SGMDPCSKRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:PRK10418  169 TDLDVVAQARILDLLESIVQKrALGMLLVTHDMGVVARLADDVAVMSHG 217
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
4686-4858 5.42e-07

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 54.01  E-value: 5.42e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4686 DILVLYNLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKML-------NGEVSLTsGHAIIRTPMGDAV 4758
Cdd:PRK10584    5 NIVEVHHLKKSVGQGEHELSILTGVELVVKRGETIALIGESGSGKSTLLAILaglddgsSGEVSLV-GQPLHQMDEEARA 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4759 DLSSAGtagvlIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTA 4838
Cdd:PRK10584   84 KLRAKH-----VGFVFQSFMLIPTLNALENVELPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALA 158
                         170       180
                  ....*....|....*....|
gi 767944871 4839 LALVGKPDILLLDEPSSGMD 4858
Cdd:PRK10584  159 RAFNGRPDVLFADEPTGNLD 178
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
3857-4051 6.31e-07

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 55.87  E-value: 6.31e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3857 VVQDLSLTFYRDQITALLGTNGAGKT-TIISMLTGLHPP----TSGTIIINGKNL-----QTdLSRVR-MELGVCPQQDI 3925
Cdd:PRK15134   24 VVNDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPpvvyPSGDIRFHGESLlhaseQT-LRGVRgNKIAMIFQEPM 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3926 L----LDNL--TVREHLLLFASIKapqwtKKELHQQVNQTLQDVDLTQ---------HQhkqtraLSGGLKRKLSLGIAF 3990
Cdd:PRK15134  103 VslnpLHTLekQLYEVLSLHRGMR-----REAARGEILNCLDRVGIRQaakrltdypHQ------LSGGERQRVMIAMAL 171
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871 3991 MGMSRTVVLDEPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGR 4051
Cdd:PRK15134  172 LTRPELLIADEPTTALDVSVQAQILQLLreLQQELNMGLLFITHNLSIVRKLADRVAVMQNGR 234
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
3861-4053 7.27e-07

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 55.57  E-value: 7.27e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3861 LSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKnlqtdlsrvrmelgvcpqqdiLLDNLTVREHLLLFA 3940
Cdd:COG4615   351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQ---------------------PVTADNREAYRQLFS 409
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3941 SI--------KAPQWTKKELHQQVNQTLQDVDLtqhQHK--------QTRALSGGLKRKLSLGIAFMgMSRTV-VLDEPT 4003
Cdd:COG4615   410 AVfsdfhlfdRLLGLDGEADPARARELLERLEL---DHKvsvedgrfSTTDLSQGQRKRLALLVALL-EDRPIlVFDEWA 485
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 767944871 4004 SGVDPCSRHSLW-DIL--LKyREGRTIIFTTHhlDEAE-ALSDRVAVLQHGRLR 4053
Cdd:COG4615   486 ADQDPEFRRVFYtELLpeLK-ARGKTVIAISH--DDRYfDLADRVLKMDYGKLV 536
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
4707-4913 8.47e-07

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 54.02  E-value: 8.47e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAII-RTPMGdavDLSSAGTAGVlIGYCPQQDALDELLTG 4785
Cdd:PRK10575   27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLdAQPLE---SWSSKAFARK-VAYLPQQLPAAEGMTV 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4786 WEHL----YYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCS 4861
Cdd:PRK10575  103 RELVaigrYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAH 182
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 767944871 4862 KRYLWQTIMKEVRE-GCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI 4913
Cdd:PRK10575  183 QVDVLALVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEL 235
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
4828-4913 9.03e-07

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 54.47  E-value: 9.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4828 SGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCL 4907
Cdd:PRK13631  178 SGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKGKILKT 257

                  ....*.
gi 767944871 4908 GSPQHI 4913
Cdd:PRK13631  258 GTPYEI 263
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
4706-4884 1.03e-06

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 55.17  E-value: 1.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4706 AVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGV--LIGYCPQqDALdeLL 4783
Cdd:COG1132   355 VLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILI-----DGVDIRDLTLESLrrQIGVVPQ-DTF--LF 426
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4784 TGwehlyyycSLR-----GIPRQCIPEV--------AGDLIRRLH--LEAHADKPVATYSGGTKRKLSTALALVGKPDIL 4848
Cdd:COG1132   427 SG--------TIReniryGRPDATDEEVeeaakaaqAHEFIEALPdgYDTVVGERGVNLSGGQRQRIAIARALLKDPPIL 498
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 767944871 4849 LLDEPSSGMDPCSKRYLWQTiMKEVREGCAAVLTSH 4884
Cdd:COG1132   499 ILDEATSALDTETEALIQEA-LERLMKGRTTIVIAH 533
PTZ00243 PTZ00243
ABC transporter; Provisional
3818-4056 1.15e-06

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 55.56  E-value: 1.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3818 NENFDNKGSSLQNREGELEGSAPGVTLVSVTKEYEGH-KAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTS 3896
Cdd:PTZ00243  635 SRHIVEGGTGGGHEATPTSERSAKTPKMKTDDFFELEpKVLLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISE 714
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3897 GtiiingknlqtdlsRVRME--LGVCPQQDILLdNLTVREHLLLFASIKApqwtkKELHQQVNQTLQDVDLTQ------- 3967
Cdd:PTZ00243  715 G--------------RVWAErsIAYVPQQAWIM-NATVRGNILFFDEEDA-----ARLADAVRVSQLEADLAQlggglet 774
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3968 HQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDP-CSRHSLWDILLKYREGRTIIFTTHHLdEAEALSDRVAV 4046
Cdd:PTZ00243  775 EIGEKGVNLSGGQKARVSLARAVYANRDVYLLDDPLSALDAhVGERVVEECFLGALAGKTRVLATHQV-HVVPRADYVVA 853
                         250
                  ....*....|
gi 767944871 4047 LQHGRLRCCG 4056
Cdd:PTZ00243  854 LGDGRVEFSG 863
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
4685-4858 1.43e-06

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 52.26  E-value: 1.43e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4685 GDILVLYNLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLT------------SGHAIIRT 4752
Cdd:cd03233     1 ASTLSWRNISFTTGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvegdihyngiPYKEFAEK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4753 PMGDAVdlssagtagvligYCPQQDALDELLTGWEHLYYYCSLRGiprqcipevaGDLIRRLhleahadkpvatySGGTK 4832
Cdd:cd03233    81 YPGEII-------------YVSEEDVHFPTLTVRETLDFALRCKG----------NEFVRGI-------------SGGER 124
                         170       180
                  ....*....|....*....|....*.
gi 767944871 4833 RKLSTALALVGKPDILLLDEPSSGMD 4858
Cdd:cd03233   125 KRVSIAEALVSRASVLCWDNSTRGLD 150
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
3847-3901 1.47e-06

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 54.74  E-value: 1.47e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767944871 3847 VTKEYeGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIII 3901
Cdd:PRK11819  330 LSKSF-GDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI 383
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
4690-4921 1.48e-06

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 53.88  E-value: 1.48e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4690 LYNLSKHYrrffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAII-RTPMGDaVDLSSAGtagv 4768
Cdd:PRK11000    6 LRNVTKAY----GDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIgEKRMND-VPPAERG---- 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4769 lIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDIL 4848
Cdd:PRK11000   77 -VGMVFQSYALYPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVF 155
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871 4849 LLDEPSSGMDPCSKRYLWQTIMK-EVREGCAAVLTSHSMEECEALCTRLAIMVNGSFKCLGSPQHI----KNRFGDGY 4921
Cdd:PRK11000  156 LLDEPLSNLDAALRVQMRIEISRlHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELyhypANRFVAGF 233
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
3858-4052 1.57e-06

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 54.35  E-value: 1.57e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3858 VQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTD------------LSRVRMELGVCPQQDI 3925
Cdd:PRK10982  264 IRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHnaneainhgfalVTEERRSTGIYAYLDI 343
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3926 LLDNL--TVREH-----LLLFASIKA-PQWTKKELHQQvnqtlqdvdlTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTV 3997
Cdd:PRK10982  344 GFNSLisNIRNYknkvgLLDNSRMKSdTQWVIDSMRVK----------TPGHRTQIGSLSGGNQQKVIIGRWLLTQPEIL 413
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871 3998 VLDEPTSGVDPCSRHSLWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVLQHGRL 4052
Cdd:PRK10982  414 MLDEPTRGIDVGAKFEIYQLIAELaKKDKGIIIISSEMPELLGITDRILVMSNGLV 469
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
4708-4884 1.67e-06

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 52.62  E-value: 1.67e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4708 QDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLSSAGTAgvlIGYCPQqdalDELL---T 4784
Cdd:cd03253    18 KDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTLDSLRRA---IGVVPQ----DTVLfndT 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4785 GWEHLYYYCslrgiprqciPEVAGDLIRRLHLEAHADKPVATY---------------SGGTKRKLSTALALVGKPDILL 4849
Cdd:cd03253    91 IGYNIRYGR----------PDATDEEVIEAAKAAQIHDKIMRFpdgydtivgerglklSGGEKQRVAIARAILKNPPILL 160
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 767944871 4850 LDEPSSGMDPCSKRYLWQTIMKeVREGCAAVLTSH 4884
Cdd:cd03253   161 LDEATSALDTHTEREIQAALRD-VSKGRTTIVIAH 194
PLN03211 PLN03211
ABC transporter G-25; Provisional
4717-4884 2.04e-06

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 54.12  E-value: 2.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4717 GECFGLLGVNGAGKSTTFKMLNGEVSltsGHAIIRTPMGDAVDLssagTAGVL--IGYCPQQDALDELLTGWEHLYYyCS 4794
Cdd:PLN03211   94 GEILAVLGPSGSGKSTLLNALAGRIQ---GNNFTGTILANNRKP----TKQILkrTGFVTQDDILYPHLTVRETLVF-CS 165
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4795 LRGIP----RQCIPEVAGDLIRRLHLEAHADKPVAT-----YSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYL 4865
Cdd:PLN03211  166 LLRLPksltKQEKILVAESVISELGLTKCENTIIGNsfirgISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRL 245
                         170
                  ....*....|....*....
gi 767944871 4866 WQTIMKEVREGCAAVLTSH 4884
Cdd:PLN03211  246 VLTLGSLAQKGKTIVTSMH 264
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
4659-4903 2.04e-06

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 54.02  E-value: 2.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4659 LQGTVKSSKDTDVEKEEKRVFEGRtngdilvlyNLSKHYRRffqniiAVQDISLGIPKGECFGLLGVNGAGKSTTF---- 4734
Cdd:PRK09700  246 LQNRFNAMKENVSNLAHETVFEVR---------NVTSRDRK------KVRDISFSVCRGEILGFAGLVGSGRTELMnclf 310
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4735 ---KMLNGEVSLTSGHAIIRTPMgDAVdlsSAGTAGVL-----IGYCP-----QQDALDELL--TGWEHLYYYCSLRgiP 4799
Cdd:PRK09700  311 gvdKRAGGEIRLNGKDISPRSPL-DAV---KKGMAYITesrrdNGFFPnfsiaQNMAISRSLkdGGYKGAMGLFHEV--D 384
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4800 RQCIPEVAGDLirrLHLEAHA-DKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCA 4878
Cdd:PRK09700  385 EQRTAENQREL---LALKCHSvNQNITELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADDGKV 461
                         250       260
                  ....*....|....*....|....*
gi 767944871 4879 AVLTSHSMEECEALCTRLAIMVNGS 4903
Cdd:PRK09700  462 ILMVSSELPEIITVCDRIAVFCEGR 486
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
3842-4053 3.50e-06

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 52.16  E-value: 3.50e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3842 VTLVSVTKEY-EGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLhPPTSGTIIINGKNLQT-DLSRVRMELGV 3919
Cdd:cd03289     3 MTVKDLTAKYtEGGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRL-LNTEGDIQIDGVSWNSvPLQKWRKAFGV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3920 CPQQdILLDNLTVREHLLLFAsikapQWTKKELHQQVNQTLQDVDLTQHQHKQT-------RALSGGLKRKLSLGIAFMG 3992
Cdd:cd03289    82 IPQK-VFIFSGTFRKNLDPYG-----KWSDEEIWKVAEEVGLKSVIEQFPGQLDfvlvdggCVLSHGHKQLMCLARSVLS 155
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871 3993 MSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHLdEAEALSDRVAVLQHGRLR 4053
Cdd:cd03289   156 KAKILLLDEPSAHLDPITYQVIRKTLKQAFADCTVILSEHRI-EAMLECQRFLVIEENKVR 215
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
4707-4872 5.03e-06

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 52.89  E-value: 5.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGEcfGLL--GVNGAGKSTTFKMLNGevsL-TSGHAIIRTPMGdavdlssagtAGVLigYCPQ-----QDA 4778
Cdd:COG4178   379 LEDLSLSLKPGE--RLLitGPSGSGKSTLLRAIAG---LwPYGSGRIARPAG----------ARVL--FLPQrpylpLGT 441
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4779 LDELLTgwehlyYYCSLRGIPRQcipEVA--------GDLIRRLHLEAHADKpvaTYSGGTKRKLSTALALVGKPDILLL 4850
Cdd:COG4178   442 LREALL------YPATAEAFSDA---ELRealeavglGHLAERLDEEADWDQ---VLSLGEQQRLAFARLLLHKPDWLFL 509
                         170       180
                  ....*....|....*....|..
gi 767944871 4851 DEPSSGMDPCSKRYLWQTIMKE 4872
Cdd:COG4178   510 DEATSALDEENEAALYQLLREE 531
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
4817-4913 5.45e-06

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 51.51  E-value: 5.45e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4817 EAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRL 4896
Cdd:PRK10619  143 ERAQGKYPVHLSGGQQQRVSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHV 222
                          90
                  ....*....|....*..
gi 767944871 4897 AIMVNGSFKCLGSPQHI 4913
Cdd:PRK10619  223 IFLHQGKIEEEGAPEQL 239
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
4710-4916 5.72e-06

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 51.29  E-value: 5.72e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4710 ISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHaiIRtpMGD-AVDLS-SAGTAGVLI-------GYC------- 4773
Cdd:PRK11264   22 IDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGT--IR--VGDiTIDTArSLSQQKGLIrqlrqhvGFVfqnfnlf 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4774 PQQDALDELLTGwehlyyYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEP 4853
Cdd:PRK11264   98 PHRTVLENIIEG------PVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMRPEVILFDEP 171
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4854 SSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRL------AIMVNGSFKCL-GSPQHIKNR 4916
Cdd:PRK11264  172 TSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAifmdqgRIVEQGPAKALfADPQQPRTR 241
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
3855-4051 6.00e-06

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 52.02  E-value: 6.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3855 KAVvQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLqTDLSRVRMELGVCPQQDILLDNLTVRE 3934
Cdd:PRK15079   35 KAV-DGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDL-LGMKDDEWRAVRSDIQMIFQDPLASLN 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3935 HLLLFASIKA-------PQWTKKELHQQVNQTLQDVDL-----TQHQHKqtraLSGGLKRKLSLGIAFMGMSRTVVLDEP 4002
Cdd:PRK15079  113 PRMTIGEIIAeplrtyhPKLSRQEVKDRVKAMMLKVGLlpnliNRYPHE----FSGGQCQRIGIARALILEPKLIICDEP 188
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767944871 4003 TSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGR 4051
Cdd:PRK15079  189 VSALDVSIQAQVVNLLqqLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGH 239
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
4809-4909 6.10e-06

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 52.18  E-value: 6.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4809 DLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKR----YLwQTIMKEVRegCAAVLTSH 4884
Cdd:PRK11144  111 KIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRellpYL-ERLAREIN--IPILYVSH 187
                          90       100
                  ....*....|....*....|....*
gi 767944871 4885 SMEECEALCTRLAIMVNGSFKCLGS 4909
Cdd:PRK11144  188 SLDEILRLADRVVVLEQGKVKAFGP 212
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
3856-4034 7.30e-06

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 50.41  E-value: 7.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3856 AVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKN-----LQTDLSRVRMELGVCPQQDILLdNL 3930
Cdd:cd03290    15 ATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNesepsFEATRSRNRYSVAYAAQKPWLL-NA 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3931 TVREHLLLFASIKapqwtkKELHQQVNQ--TLQ-DVDLTQHQhKQTRA------LSGGLKRKLSLGIAFMGMSRTVVLDE 4001
Cdd:cd03290    94 TVEENITFGSPFN------KQRYKAVTDacSLQpDIDLLPFG-DQTEIgerginLSGGQRQRICVARALYQNTNIVFLDD 166
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 767944871 4002 PTSGVD-PCSRHSLWDILLKY--REGRTIIFTTHHL 4034
Cdd:cd03290   167 PFSALDiHLSDHLMQEGILKFlqDDKRTLVLVTHKL 202
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
4668-4858 8.09e-06

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 52.43  E-value: 8.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4668 DTDVEKEEKRVFEGRTNGDIlVLYNLSKHYRrFFQNIIavQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGH 4747
Cdd:TIGR01193  455 DSEFINKKKRTELNNLNGDI-VINDVSYSYG-YGSNIL--SDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGE 530
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4748 AIIRtpmGDAVDLSSAGTAGVLIGYCPQQ------DALDELLTGWEHlyyYCSLRGIPRQC-IPEVAGDlIRRLHLEAHA 4820
Cdd:TIGR01193  531 ILLN---GFSLKDIDRHTLRQFINYLPQEpyifsgSILENLLLGAKE---NVSQDEIWAACeIAEIKDD-IENMPLGYQT 603
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 767944871  4821 DKPV--ATYSGGTKRKLSTALALVGKPDILLLDEPSSGMD 4858
Cdd:TIGR01193  604 ELSEegSSISGGQKQRIALARALLTDSKVLILDESTSNLD 643
ABC2_membrane_3 pfam12698
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter ...
4446-4612 9.39e-06

ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter family pfam01061.


Pssm-ID: 463674 [Multi-domain]  Cd Length: 345  Bit Score: 51.24  E-value: 9.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4446 NEDKILESIRQCGVALcivlgFSILSASIGSSVLFYLVSVCLCVAVIVAFQLTAFtfrkNLAATALLLSLFGYATLPWMY 4525
Cdd:pfam12698  187 KESRIKERLLVSGVSP-----LQYWLGKILGDFLVGLLQLLIILLLLFGIGIPFG----NLGLLLLLFLLYGLAYIALGY 257
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4526 LMSRIFSSSDVAFISYVSLNFIFGLCTMLITIMPrllaiiskaknlqNIYDVLKWVFTIFPQFCLGQGLVELCYNQIKYD 4605
Cdd:pfam12698  258 LLGSLFKNSEDAQSIIGIVILLLSGFFGGLFPLE-------------DPPSFLQWIFSIIPFFSPIDGLLRLIYGDSLWE 324

                   ....*..
gi 767944871  4606 LTHNFGI 4612
Cdd:pfam12698  325 IAPSLII 331
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
4701-4932 9.87e-06

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 50.86  E-value: 9.87e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4701 FQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIirtpMGDAV--DLSSAGTAGVL-----IGYC 4773
Cdd:PRK14271   31 FAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGYRY----SGDVLlgGRSIFNYRDVLefrrrVGML 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4774 PQQ------DALDELLTG--WEHLYYYCSLRGIPRQCIPEVA-GDLIR-RLhleahADKPVaTYSGGTKRKLSTALALVG 4843
Cdd:PRK14271  107 FQRpnpfpmSIMDNVLAGvrAHKLVPRKEFRGVAQARLTEVGlWDAVKdRL-----SDSPF-RLSGGQQQLLCLARTLAV 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4844 KPDILLLDEPSSGMDPCSKRYLwQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNGSF-------KCLGSPQHIKN- 4915
Cdd:PRK14271  181 NPEVLLLDEPTSALDPTTTEKI-EEFIRSLADRLTVIIVTHNLAQAARISDRAALFFDGRLveegpteQLFSSPKHAETa 259
                         250
                  ....*....|....*..
gi 767944871 4916 RFGDGYTVKVWLCKEAN 4932
Cdd:PRK14271  260 RYVAGLSGDVKDAKRGN 276
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
4823-4902 1.01e-05

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 51.65  E-value: 1.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4823 PVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:PRK10982  388 QIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDKGIIIISSEMPELLGITDRILVMSNG 467
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
3847-4053 1.09e-05

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 51.90  E-value: 1.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3847 VTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKnlqtdlsrvrmelgvcpqqdiL 3926
Cdd:PRK10522  328 VTFAYQDNGFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGK---------------------P 386
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3927 LDNLTVREHLLLFASI------------KAPQWTKKELHQQVNQTLQDVDLTQHQHKQ--TRALSGGLKRKLSLGIAFMG 3992
Cdd:PRK10522  387 VTAEQPEDYRKLFSAVftdfhlfdqllgPEGKPANPALVEKWLERLKMAHKLELEDGRisNLKLSKGQKKRLALLLALAE 466
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871 3993 MSRTVVLDEPTSGVDPCSRHSLWDILLKY-RE-GRTIIFTTHHlDEAEALSDRVAVLQHGRLR 4053
Cdd:PRK10522  467 ERDILLLDEWAADQDPHFRREFYQVLLPLlQEmGKTIFAISHD-DHYFIHADRLLEMRNGQLS 528
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
4692-4902 1.39e-05

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 51.27  E-value: 1.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHyrrfFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpMGDAVDLSSAGTA---GV 4768
Cdd:PRK10982    3 NISKS----FPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILF---QGKEIDFKSSKEAlenGI 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4769 L-----IGYCPQQDALDEL------LTGW--EHLYYYCSLRGIprqcipevagdlIRRLHLEAHADKPVATYSGGTKRKL 4835
Cdd:PRK10982   76 SmvhqeLNLVLQRSVMDNMwlgrypTKGMfvDQDKMYRDTKAI------------FDELDIDIDPRAKVATLSVSQMQMI 143
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767944871 4836 STALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVNG 4902
Cdd:PRK10982  144 EIAKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEITILRDG 210
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
4657-4890 1.65e-05

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 51.83  E-value: 1.65e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4657 STLQGTVKSSKDTD-VEKEEKRVFE------------GRTN----GDILVLYNlsKHYRRFF--------QNIIA----- 4706
Cdd:TIGR01271 1153 STLQWAVNSSIDVDgLMRSVSRVFKfidlpqeeprpsGGGGkyqlSTVLVIEN--PHAQKCWpsggqmdvQGLTAkytea 1230
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4707 ----VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSlTSGHAIIRTPMGDAVDLSSAGTAgvlIGYCPQQDALdel 4782
Cdd:TIGR01271 1231 gravLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS-TEGEIQIDGVSWNSVTLQTWRKA---FGVIPQKVFI--- 1303
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4783 LTGwehlYYYCSLRGIPR---QCIPEVAGDLIRRLHLEAHADK-------PVATYSGGTKRKLSTALALVGKPDILLLDE 4852
Cdd:TIGR01271 1304 FSG----TFRKNLDPYEQwsdEEIWKVAEEVGLKSVIEQFPDKldfvlvdGGYVLSNGHKQLMCLARSILSKAKILLLDE 1379
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 767944871  4853 PSSGMDPCSKRYLWQTiMKEVREGCAAVLTSHSME---ECE 4890
Cdd:TIGR01271 1380 PSAHLDPVTLQIIRKT-LKQSFSNCTVILSEHRVEallECQ 1419
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
4701-4884 1.89e-05

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 49.53  E-value: 1.89e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4701 FQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLN------------GEVSLtSGHAIIRtpmgdaVDLSSAGTAGV 4768
Cdd:PRK14247   13 FGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNrlielypearvsGEVYL-DGQDIFK------MDVIELRRRVQ 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4769 LIGYCPQQDALdelLTGWEHLYYYCSLRGI--PRQCIPEVAGDLIRRLHL----EAHADKPVATYSGGTKRKLSTALALV 4842
Cdd:PRK14247   86 MVFQIPNPIPN---LSIFENVALGLKLNRLvkSKKELQERVRWALEKAQLwdevKDRLDAPAGKLSGGQQQRLCIARALA 162
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 767944871 4843 GKPDILLLDEPSSGMDPCSKRYLwQTIMKEVREGCAAVLTSH 4884
Cdd:PRK14247  163 FQPEVLLADEPTANLDPENTAKI-ESLFLELKKDMTIVLVTH 203
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
4707-4884 2.67e-05

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 49.07  E-value: 2.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGevsLTSGHAIIR---TPMGDAvdlsSAGTAGVLIGYCPQQDALDELL 4783
Cdd:COG4138    12 LGPISAQVNAGELIHLIGPNGAGKSTLLARMAG---LLPGQGEILlngRPLSDW----SAAELARHRAYLSQQQSPPFAM 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4784 TGWEHLYYYCSlRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGT-KRKLSTALALVGKPDI------LLLDEPSSG 4856
Cdd:COG4138    85 PVFQYLALHQP-AGASSEAVEQLLAQLAEALGLEDKLSRPLTQLSGGEwQRVRLAAVLLQVWPTInpegqlLLLDEPMNS 163
                         170       180
                  ....*....|....*....|....*...
gi 767944871 4857 MDPCSKRYLWQTIMKEVREGCAAVLTSH 4884
Cdd:COG4138   164 LDVAQQAALDRLLRELCQQGITVVMSSH 191
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
4711-4902 2.69e-05

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 48.81  E-value: 2.69e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4711 SLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmgDAVDLSSAGTAGVLIGYCPQQDALDELLTGWEH-- 4788
Cdd:PRK10771   19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTL-----NGQDHTTTPPSRRPVSMLFQENNLFSHLTVAQNig 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4789 LYYYCSLRGIPRQciPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCskryLWQT 4868
Cdd:PRK10771   94 LGLNPGLKLNAAQ--REKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPA----LRQE 167
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 767944871 4869 IMKEVREGCAA-----VLTSHSMEECEALCTRLAIMVNG 4902
Cdd:PRK10771  168 MLTLVSQVCQErqltlLMVSHSLEDAARIAPRSLVVADG 206
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
3843-4032 2.84e-05

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 50.32  E-value: 2.84e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3843 TLVSVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIingknLQTDLSrvrmeLGVCPQ 3922
Cdd:TIGR03719    6 TMNRVSKVVPPKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEAR-----PQPGIK-----VGYLPQ 75
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3923 QDILLDNLTVREHLLL-FASIKAPQWTKKELHQQVNQ-------------TLQD----VDLTQHQHKQTRA--------- 3975
Cdd:TIGR03719   76 EPQLDPTKTVRENVEEgVAEIKDALDRFNEISAKYAEpdadfdklaaeqaELQEiidaADAWDLDSQLEIAmdalrcppw 155
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767944871  3976 ------LSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYrEGrTIIFTTH 4032
Cdd:TIGR03719  156 dadvtkLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLERHLQEY-PG-TVVAVTH 216
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
4828-4888 3.90e-05

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 48.88  E-value: 3.90e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767944871 4828 SGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMK-EVREGCAAVLTSHSMEE 4888
Cdd:PRK14258  152 SGGQQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSlRLRSELTMVIVSHNLHQ 213
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
4687-4926 4.16e-05

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 48.63  E-value: 4.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4687 ILVLYNLSKHYRR---FF--QNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRtpmgdavdls 4761
Cdd:PRK15112    4 LLEVRNLSKTFRYrtgWFrrQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLID---------- 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4762 sagtagvligycpqqdalDELLTGWEHLYYYCSLRGI---------PRQCIPEVAgDLIRRLH----------------- 4815
Cdd:PRK15112   74 ------------------DHPLHFGDYSYRSQRIRMIfqdpstslnPRQRISQIL-DFPLRLNtdlepeqrekqiietlr 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4816 ----LEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDpCSKRYLWQTIMKEVRE--GCAAVLTSHSMEEC 4889
Cdd:PRK15112  135 qvglLPDHASYYPHMLAPGQKQRLGLARALILRPKVIIADEALASLD-MSMRSQLINLMLELQEkqGISYIYVTQHLGMM 213
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 767944871 4890 EALCTRLAIMVNG-------SFKCLGSPQH------IKNRFGDGYTVKVW 4926
Cdd:PRK15112  214 KHISDQVLVMHQGevvergsTADVLASPLHeltkrlIAGHFGEALTADAW 263
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
4707-4885 5.31e-05

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 46.76  E-value: 5.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHaIIRTPMGDAVDLSSAGtagvligYCPQQDALDELLTGW 4786
Cdd:cd03223    17 LKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGR-IGMPEGEDLLFLPQRP-------YLPLGTLREQLIYPW 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4787 EHlyyycslrgiprqcipevagdlirrlhleahadkpvaTYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLW 4866
Cdd:cd03223    89 DD-------------------------------------VLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDRLY 131
                         170       180
                  ....*....|....*....|
gi 767944871 4867 QTImkevREGCAAVLT-SHS 4885
Cdd:cd03223   132 QLL----KELGITVISvGHR 147
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
4692-4753 5.88e-05

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 48.16  E-value: 5.88e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 4692 NLSKHYrrffQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKML-------NGEVSLtSGHAIIRTP 4753
Cdd:COG4604     6 NVSKRY----GGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMIsrllppdSGEVLV-DGLDVATTP 69
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
4688-4858 6.70e-05

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 48.69  E-value: 6.70e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4688 LVLYNLSKHYRRFFQniiAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIrtpmGDAV--DLSSA-- 4763
Cdd:PRK11650    4 LKLQAVRKSYDGKTQ---VIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWI----GGRVvnELEPAdr 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4764 GTAGVLIGYcpqqdALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHAD-KPvATYSGGTKRKLSTALALV 4842
Cdd:PRK11650   77 DIAMVFQNY-----ALYPHMSVRENMAYGLKIRGMPKAEIEERVAEAARILELEPLLDrKP-RELSGGQRQRVAMGRAIV 150
                         170
                  ....*....|....*.
gi 767944871 4843 GKPDILLLDEPSSGMD 4858
Cdd:PRK11650  151 REPAVFLFDEPLSNLD 166
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
4710-4918 6.80e-05

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 49.56  E-value: 6.80e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4710 ISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPmgdavdlssagtagvlIGYCPQQdALDELLTGWEHL 4789
Cdd:TIGR00957  657 ITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGS----------------VAYVPQQ-AWIQNDSLRENI 719
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  4790 YYYCSLRGIPRQCIPEvAGDLIRRLHLEAHADKPV-----ATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRY 4864
Cdd:TIGR00957  720 LFGKALNEKYYQQVLE-ACALLPDLEILPSGDRTEigekgVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKH 798
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 767944871  4865 LWQTIM--KEVREGCAAVLTSHSMEECEALcTRLAIMVNGSFKCLGSPQHIKNRFG 4918
Cdd:TIGR00957  799 IFEHVIgpEGVLKNKTRILVTHGISYLPQV-DVIIVMSGGKISEMGSYQELLQRDG 853
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
3860-4032 8.25e-05

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 46.79  E-value: 8.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3860 DLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIIngKNLQTD------LSRVRMELGvcpqqdiLLDNLTVR 3933
Cdd:PRK13541   18 DLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYY--KNCNINniakpyCTYIGHNLG-------LKLEMTVF 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3934 EHLLLFASIKAPQWTkkelhqqVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHS 4013
Cdd:PRK13541   89 ENLKFWSEIYNSAET-------LYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENRDL 161
                         170       180
                  ....*....|....*....|
gi 767944871 4014 LWD-ILLKYREGRTIIFTTH 4032
Cdd:PRK13541  162 LNNlIVMKANSGGIVLLSSH 181
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
4711-4901 1.16e-04

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 48.47  E-value: 1.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4711 SLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHaiirtpmgdavdLSSAGTAGVLIGYCPQQDALDE--------L 4782
Cdd:PRK10938   23 SLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGE------------RQSQFSHITRLSFEQLQKLVSDewqrnntdM 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4783 LTGWEHLYYYCSlrgipRQCI------PEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSG 4856
Cdd:PRK10938   91 LSPGEDDTGRTT-----AEIIqdevkdPARCEQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDG 165
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 767944871 4857 MDPCSKRYLWQTIMKEVREGCAAVLTSHSMEECEALCTRLAIMVN 4901
Cdd:PRK10938  166 LDVASRQQLAELLASLHQSGITLVLVLNRFDEIPDFVQFAGVLAD 210
PLN03140 PLN03140
ABC transporter G family member; Provisional
4722-4884 1.34e-04

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 48.69  E-value: 1.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4722 LLGVNGAGKSTTFKMLNGEVslTSGHAiirtpMGDaVDLS----SAGTAGVLIGYCPQQDALDELLTGWEHLYYYCSLRg 4797
Cdd:PLN03140  911 LMGVSGAGKTTLMDVLAGRK--TGGYI-----EGD-IRISgfpkKQETFARISGYCEQNDIHSPQVTVRESLIYSAFLR- 981
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4798 IPRQCIPE----VAGDLIRRLHLEAHADKPVAT-----YSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQT 4868
Cdd:PLN03140  982 LPKEVSKEekmmFVDEVMELVELDNLKDAIVGLpgvtgLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRT 1061
                         170
                  ....*....|....*.
gi 767944871 4869 IMKEVREGCAAVLTSH 4884
Cdd:PLN03140 1062 VRNTVDTGRTVVCTIH 1077
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
3869-4007 1.63e-04

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 48.18  E-value: 1.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3869 QITALLGTNGAGKTT----IISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCPQQDILLDNLTVREHLLLFASIKA 3944
Cdd:TIGR00956   88 ELTVVLGRPGSGCSTllktIASNTDGFHIGVEGVITYDGITPEEIKKHYRGDVVYNAETDVHFPHLTVGETLDFAARCKT 167
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871  3945 PQWTKKELHQQV-NQTLQDVDLTQHQHKQT----------RALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVD 4007
Cdd:TIGR00956  168 PQNRPDGVSREEyAKHIADVYMATYGLSHTrntkvgndfvRGVSGGERKRVSIAEASLGGAKIQCWDNATRGLD 241
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
4692-4886 1.87e-04

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 46.57  E-value: 1.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHYRRFfqniIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAI----------IRTPMGDAVDLS 4761
Cdd:COG1117    16 NLNVYYGDK----QALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMNDLIPGARVegeilldgedIYDPDVDVVELR 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4762 SAgtagvlIGYCPQQ------------------------DALDEL----LTG---WEhlyyycslrgiprqcipEVAgDl 4810
Cdd:COG1117    92 RR------VGMVFQKpnpfpksiydnvayglrlhgikskSELDEIveesLRKaalWD-----------------EVK-D- 146
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 4811 irRLHleahadKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKrylwQTI---MKEVREGCAAVLTSHSM 4886
Cdd:COG1117   147 --RLK------KSALGLSGGQQQRLCIARALAVEPEVLLMDEPTSALDPIST----AKIeelILELKKDYTIVIVTHNM 213
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
3873-4034 1.93e-04

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 47.86  E-value: 1.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3873 LLGTNGAGKTTIISMLTGLHPPTSGTIiingknlqtDLSRvRMELGVCPQQDilLDNLTVREHLLLFASIKAPQwtkkEL 3952
Cdd:PRK10636  343 LLGRNGAGKSTLIKLLAGELAPVSGEI---------GLAK-GIKLGYFAQHQ--LEFLRADESPLQHLARLAPQ----EL 406
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3953 HQQVNQTLQDVDLTQHQ-HKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTT 4031
Cdd:PRK10636  407 EQKLRDYLGGFGFQGDKvTEETRRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGALVVVSHD 486

                  ...
gi 767944871 4032 HHL 4034
Cdd:PRK10636  487 RHL 489
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
3855-4007 1.99e-04

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 47.64  E-value: 1.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3855 KAVVQDLSLTFYR-DQItALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGvcPQQDIlLDNLT-- 3931
Cdd:PRK11147  332 KQLVKDFSAQVQRgDKI-ALIGPNGCGKTTLLKLMLGQLQADSGRIHCGTKLEVAYFDQHRAELD--PEKTV-MDNLAeg 407
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3932 --------VREHLLLFasikapqwtkkelhqqvnqtLQDVdLTQHQHKQT--RALSGGLKRKLSLGIAFMGMSRTVVLDE 4001
Cdd:PRK11147  408 kqevmvngRPRHVLGY--------------------LQDF-LFHPKRAMTpvKALSGGERNRLLLARLFLKPSNLLILDE 466

                  ....*.
gi 767944871 4002 PTSGVD 4007
Cdd:PRK11147  467 PTNDLD 472
AAA_21 pfam13304
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...
4823-4887 3.42e-04

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.


Pssm-ID: 433102 [Multi-domain]  Cd Length: 303  Bit Score: 46.23  E-value: 3.42e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767944871  4823 PVATYSGGTKRKLSTALAL---VGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVLTSHSME 4887
Cdd:pfam13304  233 PAFELSDGTKRLLALLAALlsaLPKGGLLLIDEPESGLHPKLLRRLLELLKELSRNGAQLILTTHSPL 300
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
4717-4884 3.70e-04

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 45.69  E-value: 3.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4717 GECFGLLGVNGAGKSTTFKMLNGevsLTSGHAIIRTpMGDAVDLSSAGTAGVLIGYCPQQDALDELLTGWEHLYYYCSlR 4796
Cdd:PRK03695   22 GEILHLVGPNGAGKSTLLARMAG---LLPGSGSIQF-AGQPLEAWSAAELARHRAYLSQQQTPPFAMPVFQYLTLHQP-D 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4797 GIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGT-KRKLSTALALVGKPDI------LLLDEPSSGMDPCSKRYLWQTI 4869
Cdd:PRK03695   97 KTRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEwQRVRLAAVVLQVWPDInpagqlLLLDEPMNSLDVAQQAALDRLL 176
                         170
                  ....*....|....*
gi 767944871 4870 MKEVREGCAAVLTSH 4884
Cdd:PRK03695  177 SELCQQGIAVVMSSH 191
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
3843-3934 6.04e-04

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 46.27  E-value: 6.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3843 TLVSVTKEYEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIingknLQTDLSrvrmeLGVCPQ 3922
Cdd:PRK11819    8 TMNRVSKVVPPKKQILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEAR-----PAPGIK-----VGYLPQ 77
                          90
                  ....*....|..
gi 767944871 3923 QDILLDNLTVRE 3934
Cdd:PRK11819   78 EPQLDPEKTVRE 89
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
4717-4888 6.16e-04

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 46.16  E-value: 6.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4717 GECFGLLGVNGAGKSTTFKMLNGEvsltsgHaiirtPMGDAVDLssagtagVLIGycpQQDALDEllTGWE--------- 4787
Cdd:PRK10938  286 GEHWQIVGPNGAGKSTLLSLITGD------H-----PQGYSNDL-------TLFG---RRRGSGE--TIWDikkhigyvs 342
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4788 ---HLYYY--CSLR-----------GIpRQCIPE----VAGDLIRRLHLEAH-ADKPVATYSGGTKRKLSTALALVGKPD 4846
Cdd:PRK10938  343 sslHLDYRvsTSVRnvilsgffdsiGI-YQAVSDrqqkLAQQWLDILGIDKRtADAPFHSLSWGQQRLALIVRALVKHPT 421
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 767944871 4847 ILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVL-TSHSMEE 4888
Cdd:PRK10938  422 LLILDEPLQGLDPLNRQLVRRFVDVLISEGETQLLfVSHHAED 464
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
4692-4902 6.72e-04

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 45.83  E-value: 6.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4692 NLSKHY---RRFFQN----IIAVQDISLGIPKGECFGLLGVNGAGKSTTfkmlngevsltsGHAIIRTpmgdavdLSSAG 4764
Cdd:COG4172   280 DLKVWFpikRGLFRRtvghVKAVDGVSLTLRRGETLGLVGESGSGKSTL------------GLALLRL-------IPSEG 340
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4765 TAgVLIGycpqQDaLDElLTGWEHLYY-----------YCSLRgiPRQCIpevaGDLIR---RLH--------------- 4815
Cdd:COG4172   341 EI-RFDG----QD-LDG-LSRRALRPLrrrmqvvfqdpFGSLS--PRMTV----GQIIAeglRVHgpglsaaerrarvae 407
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4816 -LE------AHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDpcskrylwQTIMKEV---------REGCAA 4879
Cdd:COG4172   408 aLEevgldpAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALD--------VSVQAQIldllrdlqrEHGLAY 479
                         250       260
                  ....*....|....*....|...
gi 767944871 4880 VLTSHSMEECEALCTRLAIMVNG 4902
Cdd:COG4172   480 LFISHDLAVVRALAHRVMVMKDG 502
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
3853-4038 6.83e-04

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 43.50  E-value: 6.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3853 GHKAVVQDLSLTFYRDQITALLGTNGAGKTTIIsmltglhpptsgtiiingknlqtdlsrvrmelgvcpqQDILLdnltv 3932
Cdd:cd03227     6 RFPSYFVPNDVTFGEGSLTIITGPNGSGKSTIL-------------------------------------DAIGL----- 43
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3933 rehLLLFASikAPQWTKKELHQQVNQTLQDVDLTQHQHKqtraLSGGLKRKLSLGIAFMGMSR----TVVLDEPTSGVDP 4008
Cdd:cd03227    44 ---ALGGAQ--SATRRRSGVKAGCIVAAVSAELIFTRLQ----LSGGEKELSALALILALASLkprpLYILDEIDRGLDP 114
                         170       180       190
                  ....*....|....*....|....*....|.
gi 767944871 4009 CSRHSLWDILLKYR-EGRTIIFTTHHLDEAE 4038
Cdd:cd03227   115 RDGQALAEAILEHLvKGAQVIVITHLPELAE 145
PLN03232 PLN03232
ABC transporter C family member; Provisional
3857-4007 1.11e-03

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 45.74  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3857 VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQ----TDLSRVrmeLGVCPQQDILLDNlTV 3932
Cdd:PLN03232 1251 VLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAkfglTDLRRV---LSIIPQSPVLFSG-TV 1326
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3933 REHLLLFASIK-APQWtkKELHQQvnqTLQDV------DLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSG 4005
Cdd:PLN03232 1327 RFNIDPFSEHNdADLW--EALERA---HIKDVidrnpfGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDEATAS 1401

                  ..
gi 767944871 4006 VD 4007
Cdd:PLN03232 1402 VD 1403
PLN03130 PLN03130
ABC transporter C family member; Provisional
3872-4007 1.71e-03

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 45.11  E-value: 1.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3872 ALLGTNGAGKTTIISMLTGLHPPTSGTIIIngknlqtdlsrVRMELGVCPQQDILLdNLTVREHLLLFASIKAPQWTK-- 3949
Cdd:PLN03130  647 AIVGSTGEGKTSLISAMLGELPPRSDASVV-----------IRGTVAYVPQVSWIF-NATVRDNILFGSPFDPERYERai 714
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3950 --KELHQQVnQTLQDVDLTQHQHKQTRaLSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVD 4007
Cdd:PLN03130  715 dvTALQHDL-DLLPGGDLTEIGERGVN-ISGGQKQRVSMARAVYSNSDVYIFDDPLSALD 772
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
4714-4858 1.96e-03

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 44.39  E-value: 1.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4714 IPKGECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAII-----------RTPMgdavdLSSAGTAGVLIGYCPQQDALDEL 4782
Cdd:PRK10636   24 INPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFpgnwqlawvnqETPA-----LPQPALEYVIDGDREYRQLEAQL 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4783 LTGWEH------LYYYCSLRGIPRQCIPEVAGDLIRRLHL-EAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSS 4855
Cdd:PRK10636   99 HDANERndghaiATIHGKLDAIDAWTIRSRAASLLHGLGFsNEQLERPVSDFSGGWRMRLNLAQALICRSDLLLLDEPTN 178

                  ...
gi 767944871 4856 GMD 4858
Cdd:PRK10636  179 HLD 181
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
4797-4859 2.27e-03

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 43.54  E-value: 2.27e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767944871 4797 GIPRQCIPEVAGDLIRRLHL-EAHADKPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDP 4859
Cdd:PRK13651  135 GVSKEEAKKRAAKYIELVGLdESYLQRSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDP 198
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
3869-4047 2.29e-03

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 43.12  E-value: 2.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3869 QITALLGTNGAGKTTIISMLTGLHPPTSG---------TIIIN--GKNLQTDLSRVR---MELGVCPQQ-DILLDNLTVR 3933
Cdd:cd03236    27 QVLGLVGPNGIGKSTALKILAGKLKPNLGkfddppdwdEILDEfrGSELQNYFTKLLegdVKVIVKPQYvDLIPKAVKGK 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3934 EHLLLfasikapqwTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHS 4013
Cdd:cd03236   107 VGELL---------KKKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQRLN 177
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 767944871 4014 LWDILLKY-REGRTIIFTTHHLDEAEALSDRVAVL 4047
Cdd:cd03236   178 AARLIRELaEDDNYVLVVEHDLAVLDYLSDYIHCL 212
GguA NF040905
sugar ABC transporter ATP-binding protein;
4707-4904 2.31e-03

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 44.01  E-value: 2.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4707 VQDISLGIPKGECFGLLGVNGAGKsTTFKMlngevSL--------TSGHAIIRtpmGDAVDLSS------AGTAGV---- 4768
Cdd:NF040905  276 VDDVSLNVRRGEIVGIAGLMGAGR-TELAM-----SVfgrsygrnISGTVFKD---GKEVDVSTvsdaidAGLAYVtedr 346
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4769 ------LIgycpqqDALDELLTGwehlyyyCSLRGI-PRQCIPE-----VAGDLIRRLHLEAHA-DKPVATYSGGTKRKL 4835
Cdd:NF040905  347 kgyglnLI------DDIKRNITL-------ANLGKVsRRGVIDEneeikVAEEYRKKMNIKTPSvFQKVGNLSGGNQQKV 413
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4836 STALALVGKPDILLLDEPSSGMDPCSKrYLWQTIMKE-VREGCAAVLTSHSMEECEALCTRLAIMVNGSF 4904
Cdd:NF040905  414 VLSKWLFTDPDVLILDEPTRGIDVGAK-YEIYTIINElAAEGKGVIVISSELPELLGMCDRIYVMNEGRI 482
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
4825-4922 2.41e-03

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 44.31  E-value: 2.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4825 ATYSGGTKRKLSTALALVGKPDILLLDEPSSGMD-PCSKRYLwqTIMKEVRE--GCAAVLTSHSMEECEALCTRLAIMVN 4901
Cdd:PRK15134  424 AEFSGGQRQRIAIARALILKPSLIILDEPTSSLDkTVQAQIL--ALLKSLQQkhQLAYLFISHDLHVVRALCHQVIVLRQ 501
                          90       100
                  ....*....|....*....|.
gi 767944871 4902 GSFKCLGSPQHIKNRFGDGYT 4922
Cdd:PRK15134  502 GEVVEQGDCERVFAAPQQEYT 522
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
3857-4050 4.33e-03

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 43.75  E-value: 4.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3857 VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKnlqtdlsrvrmeLGVCPQQDILLDNlTVREHL 3936
Cdd:TIGR01271  441 VLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGR------------ISFSPQTSWIMPG-TIKDNI 507
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871  3937 LLFASIKAPQWTkkelhQQVNQTLQDVDLTQHQHKQTR-------ALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPC 4009
Cdd:TIGR01271  508 IFGLSYDEYRYT-----SVIKACQLEEDIALFPEKDKTvlgeggiTLSGGQRARISLARAVYKDADLYLLDSPFTHLDVV 582
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 767944871  4010 SRHSLWD-ILLKYREGRTIIFTTHHLDEAEAlSDRVAVLQHG 4050
Cdd:TIGR01271  583 TEKEIFEsCLCKLMSNKTRILVTSKLEHLKK-ADKILLLHEG 623
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
4828-4915 5.05e-03

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 42.53  E-value: 5.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 4828 SGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTiMKEVREGCAAVLTSHSMeecEAL--CTRLAIMVNGSFK 4905
Cdd:cd03289   140 SHGHKQLMCLARSVLSKAKILLLDEPSAHLDPITYQVIRKT-LKQAFADCTVILSEHRI---EAMleCQRFLVIEENKVR 215
                          90
                  ....*....|
gi 767944871 4906 CLGSPQHIKN 4915
Cdd:cd03289   216 QYDSIQKLLN 225
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
3857-4050 5.26e-03

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 42.54  E-value: 5.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3857 VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKnlqtdlsrvrmeLGVCPQQDILLDNlTVREHL 3936
Cdd:cd03291    52 VLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGR------------ISFSSQFSWIMPG-TIKENI 118
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3937 LLFAS---------IKAPQWTKK--ELHQQVNQTLQDVDLTqhqhkqtraLSGGLKRKLSLGIAFMGMSRTVVLDEPTSG 4005
Cdd:cd03291   119 IFGVSydeyryksvVKACQLEEDitKFPEKDNTVLGEGGIT---------LSGGQRARISLARAVYKDADLYLLDSPFGY 189
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 767944871 4006 VDPCSRHSLWD-ILLKYREGRTIIFTTHHLDEAEAlSDRVAVLQHG 4050
Cdd:cd03291   190 LDVFTEKEIFEsCVCKLMANKTRILVTSKMEHLKK-ADKILILHEG 234
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
3856-4051 5.34e-03

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 42.92  E-value: 5.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3856 AVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTI--------------IINGKNLQTDLSRVR-MELGVC 3920
Cdd:PRK10261   30 AAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVqcdkmllrrrsrqvIELSEQSAAQMRHVRgADMAMI 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3921 PQQDILLDN--LTVREHLLlfASIKAPQ-WTKKELHQQVNQTLQDVDLTQHQHKQTR---ALSGGLKRKLSLGIAFMGMS 3994
Cdd:PRK10261  110 FQEPMTSLNpvFTVGEQIA--ESIRLHQgASREEAMVEAKRMLDQVRIPEAQTILSRyphQLSGGMRQRVMIAMALSCRP 187
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767944871 3995 RTVVLDEPTSGVDPCSRHSLWDIL--LKYREGRTIIFTTHHLDEAEALSDRVAVLQHGR 4051
Cdd:PRK10261  188 AVLIADEPTTALDVTIQAQILQLIkvLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGE 246
PLN03073 PLN03073
ABC transporter F family; Provisional
3840-4050 5.53e-03

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 43.31  E-value: 5.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3840 PGVTLVSVTKE---YEGHKAVVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKnlqtdlsrVRMe 3916
Cdd:PLN03073  504 PGPPIISFSDAsfgYPGGPLLFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVFRSAK--------VRM- 574
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3917 lGVCPQQDIllDNLTVREHLLLFASIKAPqwtkKELHQQVNQTLQDVDLTQHQHKQTR-ALSGGLKRKLSLGIAFMGMSR 3995
Cdd:PLN03073  575 -AVFSQHHV--DGLDLSSNPLLYMMRCFP----GVPEQKLRAHLGSFGVTGNLALQPMyTLSGGQKSRVAFAKITFKKPH 647
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767944871 3996 TVVLDEPTSGVDPCSRHSLWDILLKYREGRTIIFTTHHL-----DEAEALSDRVAVLQHG 4050
Cdd:PLN03073  648 ILLLDEPSNHLDLDAVEALIQGLVLFQGGVLMVSHDEHLisgsvDELWVVSEGKVTPFHG 707
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
4828-4870 6.38e-03

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 43.09  E-value: 6.38e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 767944871 4828 SGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIM 4870
Cdd:PTZ00265 1360 SGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIV 1402
AAA_21 pfam13304
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...
3976-4032 7.03e-03

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.


Pssm-ID: 433102 [Multi-domain]  Cd Length: 303  Bit Score: 41.99  E-value: 7.03e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767944871  3976 LSGGLKRKLSLGIAFMGM---SRTVVLDEPTSGVDPCSRHSLWDILLKYREGRT-IIFTTH 4032
Cdd:pfam13304  237 LSDGTKRLLALLAALLSAlpkGGLLLIDEPESGLHPKLLRRLLELLKELSRNGAqLILTTH 297
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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