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Conserved domains on  [gi|530372328|ref|XP_005265131|]
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golgin subfamily A member 4 isoform X9 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1468-2109 2.55e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.33  E-value: 2.55e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1468 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRfdclKGEMEDDKSKMEKKESNLETELKSQTA 1547
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE----ISRLEQQKQILRERLANLERQLEELEA 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1548 RIMELEDHITQKTIEIESLN---EVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELE 1624
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEeklEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1625 TKKKELEHVNLSVKSKEEELKALEDRLESesaAKLAELKRKAEQKIAAIKKqLLSQMEEKEEQYKKGTEShLSELNTKLQ 1704
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEE---AELKELQAELEELEEELEE-LQEELERLEEALEELREE-LEEAEQALD 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1705 EREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQeEADSQGC------VQKTYEEKIS---------VLQRNLTE 1769
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSG-LSGILGVlselisVDEGYEAAIEaalggrlqaVVVENLNA 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1770 KEKLLQrvGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHED--------------------QSMIGH------LQEEL 1823
Cdd:TIGR02168  558 AKKAIA--FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEgflgvakdlvkfdpklrkalSYLLGGvlvvddLDNAL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1824 EEKNKKYS----------LIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELdsclvrQKEVHR 1893
Cdd:TIGR02168  636 ELAKKLRPgyrivtldgdLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL------RKELEE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1894 VEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQK 1973
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1974 DLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIkETINKAQEVEAELL 2053
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI-ESLAAEIEELEELI 868

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 530372328  2054 ESHQEETNQLLKKIAEKDDDLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKK 2109
Cdd:TIGR02168  869 EELESELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELEELREK 923
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 763-1687 6.50e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.79  E-value: 6.50e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   763 KEHEVSIQRTEKALKdqinQLELLLKERDKHLKEHQAHVENLEA--DIKRSEGELQQASAKLDV--FQSYQSATHEQTKA 838
Cdd:TIGR02168  175 KETERKLERTRENLD----RLEDILNELERQLKSLERQAEKAERykELKAELRELELALLVLRLeeLREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   839 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGN 918
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   919 KEQEQTKqilvekenmILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQEtlkkklld 998
Cdd:TIGR02168  331 KLDELAE---------ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL-------- 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   999 QEAKLKKELENTALELSQkekqfnakmlemaqansagISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE 1078
Cdd:TIGR02168  394 QIASLNNEIERLEARLER-------------------LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1079 ELqEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEegvkqdttlneLQEQLKQKSAHVNSLAQDETKLKAHL 1158
Cdd:TIGR02168  455 EL-ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER-----------LQENLEGFSEGVKALLKNQSGLSGIL 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1159 ----EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEE 1234
Cdd:TIGR02168  523 gvlsELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLG 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1235 LAIQLDICCKKTEALLeaktnelinisssktNAILSRISHCQhrttkvkealliktctvseleaqlrqlteeqntlniSF 1314
Cdd:TIGR02168  603 VAKDLVKFDPKLRKAL---------------SYLLGGVLVVD------------------------------------DL 631

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1315 QQATHQLEEKENQiksmkadiESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSL 1394
Cdd:TIGR02168  632 DNALELAKKLRPG--------YRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1395 SKQLTDLNVQL-QNSISLSEKEAAISSLRKQYDEEKCE---LLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKK 1470
Cdd:TIGR02168  704 RKELEELEEELeQLRKELEELSRQISALRKDLARLEAEveqLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1471 AQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEkkesNLETELKSQTARIM 1550
Cdd:TIGR02168  784 IEEL----EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE----DLEEQIEELSEDIE 855

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1551 ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGE---EKDNRVKEAEEKILTLENQVYSMKAELETKK 1627
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEelrELESKRSELRRELEELREKLAQLELRLEGLE 935

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530372328  1628 KELEHVNLSVKSK----EEELKALEDRLESESAAKLAELKRkAEQKIAAIKKQLLSQMEEKEEQ 1687
Cdd:TIGR02168  936 VRIDNLQERLSEEysltLEEAEALENKIEDDEEEARRRLKR-LENKIKELGPVNLAAIEEYEEL 998
PTZ00121 super family cl31754
MAEBL; Provisional
 337-1019 7.09e-13

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 74.79  E-value: 7.09e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  337 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAknlieqlEQDKGMVIAetkRQMHETLEMKEEEIAQLRSRIKQm 416
Cdd:PTZ00121 1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA-------EDAKRVEIA---RKAEDARKAEEARKAEDAKKAEA- 1180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  417 TTQGEELREQKE--KSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDvMKK 494
Cdd:PTZ00121 1181 ARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRK-FEE 1259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  495 SSEEQIAKLQKLHEKELARKEQELTKKLQTRErefQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK---AILT 571
Cdd:PTZ00121 1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKK---ADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKkadAAKK 1336

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  572 ESENKLRDLQQEAETYRTRILELESSLEKS----LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 647
Cdd:PTZ00121 1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAeaaeKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA 1416

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  648 LWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLE--KLDVKQTELESLSSELSEVLKARHKL 725
Cdd:PTZ00121 1417 KKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEakKADEAKKKAEEAKKADEAKKKAEEAK 1496

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  726 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLE 805
Cdd:PTZ00121 1497 KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  806 ADIKRSEGELQQASAKldvfqsyqsATHEQTKAYEEQLAQLQQKLLDLETERILLTK-QVAEVEAQKKDVCTELDAHKIQ 884
Cdd:PTZ00121 1577 NMALRKAEEAKKAEEA---------RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKK 1647

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  885 VQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQilveKENMILQMREGQKKEIEILTQKLSAKEDSIHILN 964
Cdd:PTZ00121 1648 KAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK----AAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 530372328  965 EEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEK 1019
Cdd:PTZ00121 1724 AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2187-2230 5.86e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


:

Pssm-ID: 197860  Cd Length: 46  Bit Score: 50.68  E-value: 5.86e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 530372328   2187 PTEFEYLRKVLFEYMMGRET--KTMAKVITTVLKFPDDQTQKILER 2230
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 158-474 1.77e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 53.53  E-value: 1.77e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   158 KEQLIQRLRRMERSLSSYRGKYSElvtAYQMLqREKKKLQGILSQSQDKSLRRIAELREELQMDQQ---AKKHLQEEFDA 234
Cdd:TIGR02169  690 LSSLQSELRRIENRLDELSQELSD---ASRKI-GEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQeieNVKSELKELEA 765

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   235 SLEEKDQYISVLQTQVSLLKQRLRNGPMNV------DVLKPLPQLEPQAEVFTKEENPESDGEPVVEDgtSVKTLETLQQ 308
Cdd:TIGR02169  766 RIEELEEDLHKLEEALNDLEARLSHSRIPEiqaelsKLEEEVSRIEARLREIEQKLNRLTLEKEYLEK--EIQELQEQRI 843

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   309 RVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGmvi 388
Cdd:TIGR02169  844 DLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS--- 920

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   389 aetkrQMHETLEMKEEEIAQLRSRIKQMTTQGEE------LREQKEKSERA----------AFEELEKALSTAQKTEEAR 452
Cdd:TIGR02169  921 -----ELKAKLEALEEELSEIEDPKGEDEEIPEEelsledVQAELQRVEEEiralepvnmlAIQEYEEVLKRLDELKEKR 995

                          330       340
                   ....*....|....*....|..
gi 530372328   453 RKLKAEMDEQIKTIEKTSEEER 474
Cdd:TIGR02169  996 AKLEEERKAILERIEEYEKKKR 1017
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1468-2109 2.55e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.33  E-value: 2.55e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1468 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRfdclKGEMEDDKSKMEKKESNLETELKSQTA 1547
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE----ISRLEQQKQILRERLANLERQLEELEA 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1548 RIMELEDHITQKTIEIESLN---EVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELE 1624
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEeklEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1625 TKKKELEHVNLSVKSKEEELKALEDRLESesaAKLAELKRKAEQKIAAIKKqLLSQMEEKEEQYKKGTEShLSELNTKLQ 1704
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEE---AELKELQAELEELEEELEE-LQEELERLEEALEELREE-LEEAEQALD 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1705 EREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQeEADSQGC------VQKTYEEKIS---------VLQRNLTE 1769
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSG-LSGILGVlselisVDEGYEAAIEaalggrlqaVVVENLNA 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1770 KEKLLQrvGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHED--------------------QSMIGH------LQEEL 1823
Cdd:TIGR02168  558 AKKAIA--FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEgflgvakdlvkfdpklrkalSYLLGGvlvvddLDNAL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1824 EEKNKKYS----------LIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELdsclvrQKEVHR 1893
Cdd:TIGR02168  636 ELAKKLRPgyrivtldgdLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL------RKELEE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1894 VEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQK 1973
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1974 DLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIkETINKAQEVEAELL 2053
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI-ESLAAEIEELEELI 868

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 530372328  2054 ESHQEETNQLLKKIAEKDDDLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKK 2109
Cdd:TIGR02168  869 EELESELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELEELREK 923
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 763-1687 6.50e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.79  E-value: 6.50e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   763 KEHEVSIQRTEKALKdqinQLELLLKERDKHLKEHQAHVENLEA--DIKRSEGELQQASAKLDV--FQSYQSATHEQTKA 838
Cdd:TIGR02168  175 KETERKLERTRENLD----RLEDILNELERQLKSLERQAEKAERykELKAELRELELALLVLRLeeLREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   839 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGN 918
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   919 KEQEQTKqilvekenmILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQEtlkkklld 998
Cdd:TIGR02168  331 KLDELAE---------ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL-------- 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   999 QEAKLKKELENTALELSQkekqfnakmlemaqansagISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE 1078
Cdd:TIGR02168  394 QIASLNNEIERLEARLER-------------------LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1079 ELqEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEegvkqdttlneLQEQLKQKSAHVNSLAQDETKLKAHL 1158
Cdd:TIGR02168  455 EL-ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER-----------LQENLEGFSEGVKALLKNQSGLSGIL 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1159 ----EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEE 1234
Cdd:TIGR02168  523 gvlsELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLG 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1235 LAIQLDICCKKTEALLeaktnelinisssktNAILSRISHCQhrttkvkealliktctvseleaqlrqlteeqntlniSF 1314
Cdd:TIGR02168  603 VAKDLVKFDPKLRKAL---------------SYLLGGVLVVD------------------------------------DL 631

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1315 QQATHQLEEKENQiksmkadiESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSL 1394
Cdd:TIGR02168  632 DNALELAKKLRPG--------YRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1395 SKQLTDLNVQL-QNSISLSEKEAAISSLRKQYDEEKCE---LLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKK 1470
Cdd:TIGR02168  704 RKELEELEEELeQLRKELEELSRQISALRKDLARLEAEveqLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1471 AQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEkkesNLETELKSQTARIM 1550
Cdd:TIGR02168  784 IEEL----EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE----DLEEQIEELSEDIE 855

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1551 ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGE---EKDNRVKEAEEKILTLENQVYSMKAELETKK 1627
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEelrELESKRSELRRELEELREKLAQLELRLEGLE 935

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530372328  1628 KELEHVNLSVKSK----EEELKALEDRLESESAAKLAELKRkAEQKIAAIKKQLLSQMEEKEEQ 1687
Cdd:TIGR02168  936 VRIDNLQERLSEEysltLEEAEALENKIEDDEEEARRRLKR-LENKIKELGPVNLAAIEEYEEL 998
PTZ00121 PTZ00121
MAEBL; Provisional
 337-1019 7.09e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 74.79  E-value: 7.09e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  337 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAknlieqlEQDKGMVIAetkRQMHETLEMKEEEIAQLRSRIKQm 416
Cdd:PTZ00121 1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA-------EDAKRVEIA---RKAEDARKAEEARKAEDAKKAEA- 1180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  417 TTQGEELREQKE--KSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDvMKK 494
Cdd:PTZ00121 1181 ARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRK-FEE 1259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  495 SSEEQIAKLQKLHEKELARKEQELTKKLQTRErefQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK---AILT 571
Cdd:PTZ00121 1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKK---ADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKkadAAKK 1336

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  572 ESENKLRDLQQEAETYRTRILELESSLEKS----LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 647
Cdd:PTZ00121 1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAeaaeKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA 1416

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  648 LWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLE--KLDVKQTELESLSSELSEVLKARHKL 725
Cdd:PTZ00121 1417 KKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEakKADEAKKKAEEAKKADEAKKKAEEAK 1496

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  726 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLE 805
Cdd:PTZ00121 1497 KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  806 ADIKRSEGELQQASAKldvfqsyqsATHEQTKAYEEQLAQLQQKLLDLETERILLTK-QVAEVEAQKKDVCTELDAHKIQ 884
Cdd:PTZ00121 1577 NMALRKAEEAKKAEEA---------RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKK 1647

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  885 VQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQilveKENMILQMREGQKKEIEILTQKLSAKEDSIHILN 964
Cdd:PTZ00121 1648 KAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK----AAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 530372328  965 EEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEK 1019
Cdd:PTZ00121 1724 AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 301-823 7.01e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.12  E-value: 7.01e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  301 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDE----------RLQELEKIKDLHMAEKTKLITQL 370
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEaqaeeyellaELARLEQDIARLEERRRELEERL 318

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  371 RDAKNLIEQLEQDKGMVIAETKRQmHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEE 450
Cdd:COG1196   319 EELEEELAELEEELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  451 ARRKLK--AEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTRERE 528
Cdd:COG1196   398 LAAQLEelEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  529 FQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQ 608
Cdd:COG1196   478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  609 SKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQA 688
Cdd:COG1196   558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  689 HIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS 768
Cdd:COG1196   638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 530372328  769 IQRTEKALKDQinQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLD 823
Cdd:COG1196   718 EEELEEEALEE--QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 309-994 3.47e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.93  E-value: 3.47e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   309 RVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDE-RLQELEKIKDLHMAEKTklitqLRDAKNLIEQLEQDKgMV 387
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEElRLEVSELEEEIEELQKE-----LYALANEISRLEQQK-QI 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   388 IAETKRQMHETLEMKEEEIAQLRSRI-------KQMTTQGEELREQKE------KSERAAFEELEKALSTAQKTEEARRK 454
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELESKLdelaeelAELEEKLEELKEELEsleaelEELEAELEELESRLEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   455 LKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEkELARKEQELtKKLQTREREFQEQMK 534
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA-ELEELEEEL-EELQEELERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   535 VAL----EKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILEL-------ESSLEKSLQ 603
Cdd:TIGR02168  465 ELReeleEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyEAAIEAALG 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   604 EN-------KNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLK------------------- 657
Cdd:TIGR02168  545 GRlqavvveNLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKdlvkfdpklrkalsyllgg 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   658 ----QQYQTEMEKLREKCEQE-----KETLLKDKEIIFQAHiEEMNEKTLEK---LDVKQTELESLSSELSEVLKARHKL 725
Cdd:TIGR02168  625 vlvvDDLDNALELAKKLRPGYrivtlDGDLVRPGGVITGGS-AKTNSSILERrreIEELEEKIEELEEKIAELEKALAEL 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   726 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQ--QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDK---HLKEHQAH 800
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDlaRLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEaeeELAEAEAE 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   801 VENLEADIKRSEGELQQASAKLDVFQSYQSATHE-----QTKAYEEQLAQLQQKLLDLETERIL--LTKQVAEVEAQKKD 873
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAELTLLNEeaanlRERLESLERRIAATERRLEDLEEQIeeLSEDIESLAAEIEE 863

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   874 VCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVyESKLEDGNKEQEQTKQILVEKENMILQMREgqkkEIEILTQKL 953
Cdd:TIGR02168  864 LEELIEELESELEALLNERASLEEALALLRSELEEL-SEELRELESKRSELRRELEELREKLAQLEL----RLEGLEVRI 938

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 530372328   954 SAKEDSihiLNEEYETKFKNQEKKMEKVKQKAKEMQETLKK 994
Cdd:TIGR02168  939 DNLQER---LSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
PTZ00121 PTZ00121
MAEBL; Provisional
 407-1146 5.07e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 68.63  E-value: 5.07e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  407 AQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERiSLQQELSRVKQ 486
Cdd:PTZ00121 1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAED-AKRVEIARKAE 1161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  487 EVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREfqEQMKVALEKSQSEYLKisQEKEQQESLALEELELQK 566
Cdd:PTZ00121 1162 DARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAE--AARKAEEERKAEEARK--AEDAKKAEAVKKAEEAKK 1237

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  567 KAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAvhlEAEKNKHNKEITVMVEKHKTElESLKHQQD 646
Cdd:PTZ00121 1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK---KAEEKKKADEAKKAEEKKKAD-EAKKKAEE 1313

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  647 ALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLE 726
Cdd:PTZ00121 1314 AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  727 EELSVLKDQTDKMKQELEAKMDEQK--NHHQQQVDSIIKEHEVSIQRTEKALKDQInqlelllkeRDKHLKEHQAHVENL 804
Cdd:PTZ00121 1394 DEAKKKAEEDKKKADELKKAAAAKKkaDEAKKKAEEKKKADEAKKKAEEAKKADEA---------KKKAEEAKKAEEAKK 1464

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  805 EADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEV----EAQKKDVCTELDA 880
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAkkaeEAKKADEAKKAEE 1544

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  881 HKiQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSI 960
Cdd:PTZ00121 1545 KK-KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE 1623

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  961 HILNEEYETKFKNQ-EKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDA 1039
Cdd:PTZ00121 1624 ELKKAEEEKKKVEQlKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK 1703

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1040 VSRLETNQKEQIESLTEVHRRELNDVISIWEKKlnQQAEELQEIHEiQLQEKEQEVAELKQKILLFGCEKEEMNKEITWL 1119
Cdd:PTZ00121 1704 AEELKKKEAEEKKKAEELKKAEEENKIKAEEAK--KEAEEDKKKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780

                         730       740
                  ....*....|....*....|....*..
gi 530372328 1120 KEEGVKQDTTLNELQEQLKQKSAHVNS 1146
Cdd:PTZ00121 1781 IEEELDEEDEKRRMEVDKKIKDIFDNF 1807
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 725-1048 6.82e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 6.82e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  725 LEEELSVLKDQTDKMK--QELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVE 802
Cdd:COG1196   198 LERQLEPLERQAEKAEryRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELE 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  803 NLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHK 882
Cdd:COG1196   278 ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  883 IQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVekenmILQMREGQKKEIEILTQKLSAKEDSIHI 962
Cdd:COG1196   358 AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE-----LEEAEEALLERLERLEEELEELEEALAE 432

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  963 LNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSR 1042
Cdd:COG1196   433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512


                  ....*.
gi 530372328 1043 LETNQK 1048
Cdd:COG1196   513 ALLLAG 518
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1469-2108 7.18e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 7.18e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1469 KKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDclkgEMEDDKSKMEKKESNLETELKSQTAR 1548
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE----EAQAEEYELLAELARLEQDIARLEER 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1549 IMELEDHITQKTIEIESLNEVLKNYNQQKD---IEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELET 1625
Cdd:COG1196   311 RRELEERLEELEEELAELEEELEELEEELEeleEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1626 KKKELehvnLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQykkgteSHLSELNTKLQE 1705
Cdd:COG1196   391 ALRAA----AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA------EEEAELEEEEEA 460

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1706 REREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETV 1785
Cdd:COG1196   461 LLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAAL 540

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1786 SSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGH---LQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQK 1862
Cdd:COG1196   541 EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRatfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGD 620

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1863 TLQEKELTCQILEQKIKELDSCLVRQKEVhRVEMEELtskyeklqalqqmdgrnkptelleenteekskshlvqpkllsn 1942
Cdd:COG1196   621 TLLGRTLVAARLEAALRRAVTLAGRLREV-TLEGEGG------------------------------------------- 656

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1943 meaqhNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMRE 2022
Cdd:COG1196   657 -----SAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 2023 FNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEK-------DDDLKRTAKRYEEildareeeMTAK 2095
Cdd:COG1196   732 AEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpvnllaIEEYEELEERYDF--------LSEQ 803

                         650
                  ....*....|...
gi 530372328 2096 VRDLQTQLEELQK 2108
Cdd:COG1196   804 REDLEEARETLEE 816
PTZ00121 PTZ00121
MAEBL; Provisional
 1412-1880 1.04e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.47  E-value: 1.04e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1412 SEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQiQLEL 1491
Cdd:PTZ00121 1286 AEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE-AAEE 1364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1492 KSKEAYEKDEQINLLKEELD---QQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARimeledhitqktieiESLNE 1568
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKADAAKkkaEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAK---------------KKAEE 1429

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1569 VLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQvysMKAELETKKKELEHVNLSVKSKEEELKALE 1648
Cdd:PTZ00121 1430 KKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAK---KKAEEAKKADEAKKKAEEAKKKADEAKKAA 1506

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1649 DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETL 1728
Cdd:PTZ00121 1507 EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEA 1586

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1729 --IVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQ-RNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHA 1805
Cdd:PTZ00121 1587 kkAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEE 1666

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530372328 1806 EAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKE 1880
Cdd:PTZ00121 1667 AKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEE 1741
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 337-1204 7.55e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.53  E-value: 7.55e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   337 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETkrqmheTLEMKEEEIAQLRSRIKQM 416
Cdd:pfam02463  171 KKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEY------LLYLDYLKLNEERIDLLQE 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   417 TTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSS 496
Cdd:pfam02463  245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   497 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKS--QSEYLKISQEKEQQESLALEELELQKKAILTESE 574
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLeqLEEELLAKKKLESERLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   575 NKLRDLQQEAETYRTRILELESSLEKSLQENKnqskdLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQ 654
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEE-----ESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQL 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   655 VLKQQYQTEMEKLREkcEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKD 734
Cdd:pfam02463  480 VKLQEQLELLLSRQK--LEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATA 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   735 QTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGE 814
Cdd:pfam02463  558 DEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   815 LQQASAKLDVFQSYQSATHEQTkayEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEK 894
Cdd:pfam02463  638 KESAKAKESGLRKGVSLEEGLA---EKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKK 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   895 QNSEMEQKVKSLTQVYESKL-EDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKN 973
Cdd:pfam02463  715 LKLEAEELLADRVQEAQDKInEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEE 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   974 QEKKMEKVKQKAKEmqetlKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIES 1053
Cdd:pfam02463  795 KLKAQEEELRALEE-----ELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELL 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1054 LTEVHRRELNDVISIWEKKLNQQAEELQEIHE-IQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNE 1132
Cdd:pfam02463  870 QELLLKEEELEEQKLKDELESKEEKEKEEKKElEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKE 949

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530372328  1133 LQEQLKQKSAHVNSLAQDEtklKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTD 1204
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLA---KEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 321-640 1.12e-08

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 60.52  E-value: 1.12e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   321 KETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQ----LEQDKGMVIAETKRQMH 396
Cdd:pfam17380  281 QKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQermaMERERELERIRQEERKR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   397 ETLEMKEEEIAQLRSRIKQMttqgEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKaemdEQIKTIEKTSEEERIS 476
Cdd:pfam17380  361 ELERIRQEEIAMEISRMREL----ERLQMERQQKNERVRQELEAARKVKILEEERQRKIQ----QQKVEMEQIRAEQEEA 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   477 LQQELSRVKQEVVDVMKKSSEEQIAK---LQKLHEKELARKEQELTKKLQTRER-EFQEQMKVALEKSQSEYLKISQEKE 552
Cdd:pfam17380  433 RQREVRRLEEERAREMERVRLEEQERqqqVERLRQQEEERKRKKLELEKEKRDRkRAEEQRRKILEKELEERKQAMIEEE 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   553 QQESLALEELELQKKAILTESEnklrdlQQEAETYRTRILELESslEKSLQENKNQSKDLAVHLEA-EKNKHNKEITVMV 631
Cdd:pfam17380  513 RKRKLLEKEMEERQKAIYEEER------RREAEEERRKQQEMEE--RRRIQEQMRKATEERSRLEAmEREREMMRQIVES 584


                   ....*....
gi 530372328   632 EKHKTELES 640
Cdd:pfam17380  585 EKARAEYEA 593
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2187-2230 5.86e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 50.68  E-value: 5.86e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 530372328   2187 PTEFEYLRKVLFEYMMGRET--KTMAKVITTVLKFPDDQTQKILER 2230
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 158-474 1.77e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.53  E-value: 1.77e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   158 KEQLIQRLRRMERSLSSYRGKYSElvtAYQMLqREKKKLQGILSQSQDKSLRRIAELREELQMDQQ---AKKHLQEEFDA 234
Cdd:TIGR02169  690 LSSLQSELRRIENRLDELSQELSD---ASRKI-GEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQeieNVKSELKELEA 765

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   235 SLEEKDQYISVLQTQVSLLKQRLRNGPMNV------DVLKPLPQLEPQAEVFTKEENPESDGEPVVEDgtSVKTLETLQQ 308
Cdd:TIGR02169  766 RIEELEEDLHKLEEALNDLEARLSHSRIPEiqaelsKLEEEVSRIEARLREIEQKLNRLTLEKEYLEK--EIQELQEQRI 843

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   309 RVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGmvi 388
Cdd:TIGR02169  844 DLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS--- 920

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   389 aetkrQMHETLEMKEEEIAQLRSRIKQMTTQGEE------LREQKEKSERA----------AFEELEKALSTAQKTEEAR 452
Cdd:TIGR02169  921 -----ELKAKLEALEEELSEIEDPKGEDEEIPEEelsledVQAELQRVEEEiralepvnmlAIQEYEEVLKRLDELKEKR 995

                          330       340
                   ....*....|....*....|..
gi 530372328   453 RKLKAEMDEQIKTIEKTSEEER 474
Cdd:TIGR02169  996 AKLEEERKAILERIEEYEKKKR 1017
mukB PRK04863
chromosome partition protein MukB;
159-426 3.59e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 52.65  E-value: 3.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  159 EQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQS---QDKSL-RRIAELREELQMDQQAKKHLQ----- 229
Cdd:PRK04863  840 RQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLnllADETLaDRVEEIREQLDEAEEAKRFVQqhgna 919

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  230 ----EEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQlepQAEVFTKEENPESDGEpvvEDGTSvktlET 305
Cdd:PRK04863  920 laqlEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQ---RRAHFSYEDAAEMLAK---NSDLN----EK 989

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  306 LQQRVKRQENLLKRCKETIQSHKEQCTL-------LTSEKEALQEQLDERLQELEKI--------KDLHMAEKTKLITQL 370
Cdd:PRK04863  990 LRQRLEQAEQERTRAREQLRQAQAQLAQynqvlasLKSSYDAKRQMLQELKQELQDLgvpadsgaEERARARRDELHARL 1069

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 530372328  371 RDAKNLIEQLEQdkgmviaetkrqmheTLEMKEEEIAQLRSRIKQMTTQGEELREQ 426
Cdd:PRK04863 1070 SANRSRRNQLEK---------------QLTFCEAEMDNLTKKLRKLERDYHEMREQ 1110
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2188-2227 1.37e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 43.88  E-value: 1.37e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 530372328  2188 TEFEYLRKVLFEYMMGRET---KTMAKVITTVLKFPDDQTQKI 2227
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1483-2152 2.53e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.58  E-value: 2.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1483 KELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIE 1562
Cdd:pfam02463  207 KKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEE 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1563 IESLNEVLKNYNQQKDIehkelvqKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEE 1642
Cdd:pfam02463  287 ELKLLAKEEEELKSELL-------KLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1643 ELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQykkgteshlSELNTKLQEREREVHILEEKLKSVES 1722
Cdd:pfam02463  360 ELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEE---------KEAQLLLELARQLEDLLKEEKKEELE 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1723 SQSETLIVPRSAKNVAAyTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKL 1802
Cdd:pfam02463  431 ILEEEEESIELKQGKLT-EEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGL 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1803 EHAEAkqhedQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELD 1882
Cdd:pfam02463  510 KVLLA-----LIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLI 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1883 SCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQ 1962
Cdd:pfam02463  585 PKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEV 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1963 KLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETI 2042
Cdd:pfam02463  665 KASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQK 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  2043 NKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGN 2122
Cdd:pfam02463  745 IDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLI 824

                          650       660       670
                   ....*....|....*....|....*....|
gi 530372328  2123 DNTQLAQKTTLISDSKLKEQEFREQIHNLE 2152
Cdd:pfam02463  825 EQEEKIKEEELEELALELKEEQKLEKLAEE 854
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
139-426 1.51e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 1.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  139 PSDMDSEAEDLVGNSDSLNK-EQLIQRLRRMERSLS---SYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLR-RIAE 213
Cdd:COG4913   220 EPDTFEAADALVEHFDDLERaHEALEDAREQIELLEpirELAERYAAARERLAELEYLRAALRLWFAQRRLELLEaELEE 299

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  214 LREELQMDQQAKKHLQEEFDASLEEKDQyisvlqtqvsLLKQRLRNGpmnVDVLKPLPQLEPQAEvftkeenpesdgepv 293
Cdd:COG4913   300 LRAELARLEAELERLEARLDALREELDE----------LEAQIRGNG---GDRLEQLEREIERLE--------------- 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  294 vedgtsvKTLETLQQRVKRQENLLKRCKETIQSHKEqctlltsEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDA 373
Cdd:COG4913   352 -------RELEERERRRARLEALLAALGLPLPASAE-------EFAALRAEAAALLEALEEELEALEEALAEAEAALRDL 417

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 530372328  374 KNLIEQLEQdkgmviaetkrqmhetlemkeeEIAQLRSRIKQMTTQGEELREQ 426
Cdd:COG4913   418 RRELRELEA----------------------EIASLERRKSNIPARLLALRDA 448
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1468-2109 2.55e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.33  E-value: 2.55e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1468 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRfdclKGEMEDDKSKMEKKESNLETELKSQTA 1547
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE----ISRLEQQKQILRERLANLERQLEELEA 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1548 RIMELEDHITQKTIEIESLN---EVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELE 1624
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEeklEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1625 TKKKELEHVNLSVKSKEEELKALEDRLESesaAKLAELKRKAEQKIAAIKKqLLSQMEEKEEQYKKGTEShLSELNTKLQ 1704
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEE---AELKELQAELEELEEELEE-LQEELERLEEALEELREE-LEEAEQALD 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1705 EREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQeEADSQGC------VQKTYEEKIS---------VLQRNLTE 1769
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSG-LSGILGVlselisVDEGYEAAIEaalggrlqaVVVENLNA 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1770 KEKLLQrvGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHED--------------------QSMIGH------LQEEL 1823
Cdd:TIGR02168  558 AKKAIA--FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEgflgvakdlvkfdpklrkalSYLLGGvlvvddLDNAL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1824 EEKNKKYS----------LIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELdsclvrQKEVHR 1893
Cdd:TIGR02168  636 ELAKKLRPgyrivtldgdLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL------RKELEE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1894 VEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQK 1973
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1974 DLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIkETINKAQEVEAELL 2053
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI-ESLAAEIEELEELI 868

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 530372328  2054 ESHQEETNQLLKKIAEKDDDLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKK 2109
Cdd:TIGR02168  869 EELESELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELEELREK 923
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 763-1687 6.50e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.79  E-value: 6.50e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   763 KEHEVSIQRTEKALKdqinQLELLLKERDKHLKEHQAHVENLEA--DIKRSEGELQQASAKLDV--FQSYQSATHEQTKA 838
Cdd:TIGR02168  175 KETERKLERTRENLD----RLEDILNELERQLKSLERQAEKAERykELKAELRELELALLVLRLeeLREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   839 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGN 918
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   919 KEQEQTKqilvekenmILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQEtlkkklld 998
Cdd:TIGR02168  331 KLDELAE---------ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL-------- 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   999 QEAKLKKELENTALELSQkekqfnakmlemaqansagISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE 1078
Cdd:TIGR02168  394 QIASLNNEIERLEARLER-------------------LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1079 ELqEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEegvkqdttlneLQEQLKQKSAHVNSLAQDETKLKAHL 1158
Cdd:TIGR02168  455 EL-ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER-----------LQENLEGFSEGVKALLKNQSGLSGIL 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1159 ----EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEE 1234
Cdd:TIGR02168  523 gvlsELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLG 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1235 LAIQLDICCKKTEALLeaktnelinisssktNAILSRISHCQhrttkvkealliktctvseleaqlrqlteeqntlniSF 1314
Cdd:TIGR02168  603 VAKDLVKFDPKLRKAL---------------SYLLGGVLVVD------------------------------------DL 631

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1315 QQATHQLEEKENQiksmkadiESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSL 1394
Cdd:TIGR02168  632 DNALELAKKLRPG--------YRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1395 SKQLTDLNVQL-QNSISLSEKEAAISSLRKQYDEEKCE---LLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKK 1470
Cdd:TIGR02168  704 RKELEELEEELeQLRKELEELSRQISALRKDLARLEAEveqLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1471 AQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEkkesNLETELKSQTARIM 1550
Cdd:TIGR02168  784 IEEL----EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE----DLEEQIEELSEDIE 855

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1551 ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGE---EKDNRVKEAEEKILTLENQVYSMKAELETKK 1627
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEelrELESKRSELRRELEELREKLAQLELRLEGLE 935

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530372328  1628 KELEHVNLSVKSK----EEELKALEDRLESESAAKLAELKRkAEQKIAAIKKQLLSQMEEKEEQ 1687
Cdd:TIGR02168  936 VRIDNLQERLSEEysltLEEAEALENKIEDDEEEARRRLKR-LENKIKELGPVNLAAIEEYEEL 998
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 943-1790 3.56e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.49  E-value: 3.56e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   943 KKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEK------VKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQ 1016
Cdd:TIGR02169  183 EENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKreyegyELLKEKEALERQKEAIERQLASLEEELEKLTEEISE 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1017 KEKQFNAKMLEMAQANsAGISDAVSRLETNQKEQIESLtEVHRRELNDVISIWEKKLNQQAEELQEIhEIQLQEKEQEVA 1096
Cdd:TIGR02169  263 LEKRLEEIEQLLEELN-KKIKDLGEEEQLRVKEKIGEL-EAEIASLERSIAEKERELEDAEERLAKL-EAEIDKLLAEIE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1097 ELKQKIllfgcekEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQ 1176
Cdd:TIGR02169  340 ELEREI-------EEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQ 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1177 EQLVELKMLAEEDKRKVSELTSKLKTTDEEfqslkssheksnksLEDKSLEFKKLSEELaiqldiccKKTEALLEAKTNE 1256
Cdd:TIGR02169  413 EELQRLSEELADLNAAIAGIEAKINELEEE--------------KEDKALEIKKQEWKL--------EQLAADLSKYEQE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1257 LINISSsKTNAILSRISHCQHRttkvkealliktctVSELEAQLRQLTEEQntlnISFQQAThqlEEKENQIKSMKADIE 1336
Cdd:TIGR02169  471 LYDLKE-EYDRVEKELSKLQRE--------------LAEAEAQARASEERV----RGGRAVE---EVLKASIQGVHGTVA 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1337 SLVTEKE----ALQKEGGNQQQAA-----SEKESCITQLKkelSENINAVTLMKEELKEKKVEISSLSKQ---------L 1398
Cdd:TIGR02169  529 QLGSVGEryatAIEVAAGNRLNNVvveddAVAKEAIELLK---RRKAGRATFLPLNKMRDERRDLSILSEdgvigfavdL 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1399 TDLNVQLQNSIS------------------------------LSEKEAAI---SSLRKQYDEEKCELLDQVQDLSFKVDT 1445
Cdd:TIGR02169  606 VEFDPKYEPAFKyvfgdtlvvedieaarrlmgkyrmvtlegeLFEKSGAMtggSRAPRGGILFSRSEPAELQRLRERLEG 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1446 LSKEKISALEQVDdwsnkfsewkkKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEME 1525
Cdd:TIGR02169  686 LKRELSSLQSELR-----------RIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIE 754

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1526 DDKSKM---EKKESNLETELKSQTARIMELEDHITQKTI-EIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNR 1601
Cdd:TIGR02169  755 NVKSELkelEARIEELEEDLHKLEEALNDLEARLSHSRIpEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKE 834

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1602 VKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLEsesaaKLAELKRKAEQKIAAIKKQLlsqm 1681
Cdd:TIGR02169  835 IQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLG-----DLKKERDELEAQLRELERKI---- 905

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1682 EEKEEQYKKgTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQ------------EEADSQ 1749
Cdd:TIGR02169  906 EELEAQIEK-KRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEiralepvnmlaiQEYEEV 984

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|.
gi 530372328  1750 GCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFE 1790
Cdd:TIGR02169  985 LKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFMEAFE 1025
PTZ00121 PTZ00121
MAEBL; Provisional
 337-1019 7.09e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 74.79  E-value: 7.09e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  337 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAknlieqlEQDKGMVIAetkRQMHETLEMKEEEIAQLRSRIKQm 416
Cdd:PTZ00121 1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA-------EDAKRVEIA---RKAEDARKAEEARKAEDAKKAEA- 1180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  417 TTQGEELREQKE--KSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDvMKK 494
Cdd:PTZ00121 1181 ARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRK-FEE 1259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  495 SSEEQIAKLQKLHEKELARKEQELTKKLQTRErefQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK---AILT 571
Cdd:PTZ00121 1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKK---ADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKkadAAKK 1336

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  572 ESENKLRDLQQEAETYRTRILELESSLEKS----LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 647
Cdd:PTZ00121 1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAeaaeKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA 1416

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  648 LWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLE--KLDVKQTELESLSSELSEVLKARHKL 725
Cdd:PTZ00121 1417 KKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEakKADEAKKKAEEAKKADEAKKKAEEAK 1496

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  726 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLE 805
Cdd:PTZ00121 1497 KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  806 ADIKRSEGELQQASAKldvfqsyqsATHEQTKAYEEQLAQLQQKLLDLETERILLTK-QVAEVEAQKKDVCTELDAHKIQ 884
Cdd:PTZ00121 1577 NMALRKAEEAKKAEEA---------RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKK 1647

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  885 VQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQilveKENMILQMREGQKKEIEILTQKLSAKEDSIHILN 964
Cdd:PTZ00121 1648 KAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK----AAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 530372328  965 EEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEK 1019
Cdd:PTZ00121 1724 AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1293-2106 2.33e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.78  E-value: 2.33e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1293 VSELEAQLRQLtEEQNTLNISFQQATHQLEEKenQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSE 1372
Cdd:TIGR02168  195 LNELERQLKSL-ERQAEKAERYKELKAELREL--ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1373 NINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQnsiSLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKIS 1452
Cdd:TIGR02168  272 LRLEVSELEEEIEELQKELYALANEISRLEQQKQ---ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1453 ALEQVDDWSNKFSEWKKKAQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEELdqqnkrfdclkGEMEDDKSKME 1532
Cdd:TIGR02168  349 LKEELESLEAELEELEAELEEL----ESRLEELEEQLETLRSKVAQLELQIASLNNEI-----------ERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1533 KKESNLETELKSQTARIMELEDHITQKTIEieslnevlknynqQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTL 1612
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKELQAELE-------------ELEEELEELQEELERLEEALEELREELEEAEQALDAA 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1613 ENQVYSMKAELETkkkelehvnlsvkskeeeLKALEDRLESESAAKLAELKrkaEQKIAAIKKQLLSQMEEKEEQYKKGT 1692
Cdd:TIGR02168  481 ERELAQLQARLDS------------------LERLQENLEGFSEGVKALLK---NQSGLSGILGVLSELISVDEGYEAAI 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1693 ESHLSE-LNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQR------ 1765
Cdd:TIGR02168  540 EAALGGrLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkals 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1766 ----------------NLTEKEKLLQRVGQEKEETVSSHF-------EMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEE 1822
Cdd:TIGR02168  620 yllggvlvvddldnalELAKKLRPGYRIVTLDGDLVRPGGvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKA 699

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1823 LEEKNKKYSLIVAQHVEKEggknniQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSK 1902
Cdd:TIGR02168  700 LAELRKELEELEEELEQLR------KELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1903 YEKLQALQQMDGRNKPTELLEENTEEKSKSHLvqpkllSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEH 1982
Cdd:TIGR02168  774 EEELAEAEAEIEELEAQIEQLKEELKALREAL------DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1983 QQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQE---- 2058
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKlaql 927

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 530372328  2059 ---------ETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEEL 2106
Cdd:TIGR02168  928 elrleglevRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 301-823 7.01e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.12  E-value: 7.01e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  301 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDE----------RLQELEKIKDLHMAEKTKLITQL 370
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEaqaeeyellaELARLEQDIARLEERRRELEERL 318

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  371 RDAKNLIEQLEQDKGMVIAETKRQmHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEE 450
Cdd:COG1196   319 EELEEELAELEEELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  451 ARRKLK--AEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTRERE 528
Cdd:COG1196   398 LAAQLEelEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  529 FQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQ 608
Cdd:COG1196   478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  609 SKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQA 688
Cdd:COG1196   558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  689 HIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS 768
Cdd:COG1196   638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 530372328  769 IQRTEKALKDQinQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLD 823
Cdd:COG1196   718 EEELEEEALEE--QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 303-587 1.21e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.35  E-value: 1.21e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  303 LETLQQRVKRQENLLKRCKETIQSHKEQctllTSEKEALQEQLDERLQELEKikdlhmaEKTKLITQLRDAKNLIEQLEQ 382
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAE----LAELEAELEELRLELEELEL-------ELEEAQAEEYELLAELARLEQ 302

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  383 DKgMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSEraafEELEKALSTAQKTEEARRKLKAEMDEQ 462
Cdd:COG1196   303 DI-ARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE----EELEEAEAELAEAEEALLEAEAELAEA 377

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  463 IKTIEKTSEEERISLQQELSRVKQ-EVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQ 541
Cdd:COG1196   378 EEELEELAEELLEALRAAAELAAQlEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE 457

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 530372328  542 SEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETY 587
Cdd:COG1196   458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 569-1338 2.91e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.32  E-value: 2.91e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   569 ILTESENKLRDLQQEAET---YRtRILELESSLEKSLQENKNQSkdlavhLEAEKNKHNKEITVMVEKHKtELESLKHQQ 645
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKaerYK-ELKAELRELELALLVLRLEE------LREELEELQEELKEAEEELE-ELTAELQEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   646 DALWTEKlqvlkqqyQTEMEKLREKCEQEKETLLKDKEIIfqAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKL 725
Cdd:TIGR02168  266 EEKLEEL--------RLEVSELEEEIEELQKELYALANEI--SRLEQQKQILRERLANLERQLEELEAQLEELESKLDEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   726 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSiikehevsiQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLE 805
Cdd:TIGR02168  336 AEELAELEEKLEELKEELESLEAELEELEAELEEL---------ESRLEELEEQLETLRSKVAQLELQIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   806 ADIKRSEGELQQASakldvfqsyQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKdvctELDAHKIQV 885
Cdd:TIGR02168  407 ARLERLEDRRERLQ---------QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALE----ELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   886 QDLMQQLEKQNSEMEQKVKSLtqvyESKLEDGNKEQEQTKQILVEKENM---------ILQMREGQKKEIE--------- 947
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSL----ERLQENLEGFSEGVKALLKNQSGLsgilgvlseLISVDEGYEAAIEaalggrlqa 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   948 ILTQKLSAKEDSIHILNEEYETK-----------FKNQEKKMEKVKQKAKEMQetLKKKLLDQEAKLKKELEN------- 1009
Cdd:TIGR02168  550 VVVENLNAAKKAIAFLKQNELGRvtflpldsikgTEIQGNDREILKNIEGFLG--VAKDLVKFDPKLRKALSYllggvlv 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1010 -----TALELSQKEK-QFNAKMLEMAQANSAGISdavsrleTNQKEQIESLTEVHRRELNDVisiwEKKLNQQAEELQEI 1083
Cdd:TIGR02168  628 vddldNALELAKKLRpGYRIVTLDGDLVRPGGVI-------TGGSAKTNSSILERRREIEEL----EEKIEELEEKIAEL 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1084 hEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEV 1163
Cdd:TIGR02168  697 -EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1164 DLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEElaiqldicc 1243
Cdd:TIGR02168  776 ELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ--------- 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1244 KKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALliktctvSELEAQLRQLTEEQNTLNISFQQATHQLEE 1323
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL-------ALLRSELEELSEELRELESKRSELRRELEE 919

                          810
                   ....*....|....*
gi 530372328  1324 KENQIKSMKADIESL 1338
Cdd:TIGR02168  920 LREKLAQLELRLEGL 934
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 309-994 3.47e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.93  E-value: 3.47e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   309 RVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDE-RLQELEKIKDLHMAEKTklitqLRDAKNLIEQLEQDKgMV 387
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEElRLEVSELEEEIEELQKE-----LYALANEISRLEQQK-QI 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   388 IAETKRQMHETLEMKEEEIAQLRSRI-------KQMTTQGEELREQKE------KSERAAFEELEKALSTAQKTEEARRK 454
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELESKLdelaeelAELEEKLEELKEELEsleaelEELEAELEELESRLEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   455 LKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEkELARKEQELtKKLQTREREFQEQMK 534
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA-ELEELEEEL-EELQEELERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   535 VAL----EKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILEL-------ESSLEKSLQ 603
Cdd:TIGR02168  465 ELReeleEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyEAAIEAALG 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   604 EN-------KNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLK------------------- 657
Cdd:TIGR02168  545 GRlqavvveNLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKdlvkfdpklrkalsyllgg 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   658 ----QQYQTEMEKLREKCEQE-----KETLLKDKEIIFQAHiEEMNEKTLEK---LDVKQTELESLSSELSEVLKARHKL 725
Cdd:TIGR02168  625 vlvvDDLDNALELAKKLRPGYrivtlDGDLVRPGGVITGGS-AKTNSSILERrreIEELEEKIEELEEKIAELEKALAEL 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   726 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQ--QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDK---HLKEHQAH 800
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDlaRLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEaeeELAEAEAE 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   801 VENLEADIKRSEGELQQASAKLDVFQSYQSATHE-----QTKAYEEQLAQLQQKLLDLETERIL--LTKQVAEVEAQKKD 873
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAELTLLNEeaanlRERLESLERRIAATERRLEDLEEQIeeLSEDIESLAAEIEE 863

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   874 VCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVyESKLEDGNKEQEQTKQILVEKENMILQMREgqkkEIEILTQKL 953
Cdd:TIGR02168  864 LEELIEELESELEALLNERASLEEALALLRSELEEL-SEELRELESKRSELRRELEELREKLAQLEL----RLEGLEVRI 938

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 530372328   954 SAKEDSihiLNEEYETKFKNQEKKMEKVKQKAKEMQETLKK 994
Cdd:TIGR02168  939 DNLQER---LSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
PTZ00121 PTZ00121
MAEBL; Provisional
 407-1146 5.07e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 68.63  E-value: 5.07e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  407 AQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERiSLQQELSRVKQ 486
Cdd:PTZ00121 1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAED-AKRVEIARKAE 1161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  487 EVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREfqEQMKVALEKSQSEYLKisQEKEQQESLALEELELQK 566
Cdd:PTZ00121 1162 DARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAE--AARKAEEERKAEEARK--AEDAKKAEAVKKAEEAKK 1237

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  567 KAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAvhlEAEKNKHNKEITVMVEKHKTElESLKHQQD 646
Cdd:PTZ00121 1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK---KAEEKKKADEAKKAEEKKKAD-EAKKKAEE 1313

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  647 ALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLE 726
Cdd:PTZ00121 1314 AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  727 EELSVLKDQTDKMKQELEAKMDEQK--NHHQQQVDSIIKEHEVSIQRTEKALKDQInqlelllkeRDKHLKEHQAHVENL 804
Cdd:PTZ00121 1394 DEAKKKAEEDKKKADELKKAAAAKKkaDEAKKKAEEKKKADEAKKKAEEAKKADEA---------KKKAEEAKKAEEAKK 1464

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  805 EADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEV----EAQKKDVCTELDA 880
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAkkaeEAKKADEAKKAEE 1544

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  881 HKiQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSI 960
Cdd:PTZ00121 1545 KK-KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE 1623

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  961 HILNEEYETKFKNQ-EKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDA 1039
Cdd:PTZ00121 1624 ELKKAEEEKKKVEQlKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK 1703

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1040 VSRLETNQKEQIESLTEVHRRELNDVISIWEKKlnQQAEELQEIHEiQLQEKEQEVAELKQKILLFGCEKEEMNKEITWL 1119
Cdd:PTZ00121 1704 AEELKKKEAEEKKKAEELKKAEEENKIKAEEAK--KEAEEDKKKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780

                         730       740
                  ....*....|....*....|....*..
gi 530372328 1120 KEEGVKQDTTLNELQEQLKQKSAHVNS 1146
Cdd:PTZ00121 1781 IEEELDEEDEKRRMEVDKKIKDIFDNF 1807
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 340-659 5.12e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.42  E-value: 5.12e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  340 ALQEQLDERLQELEKIKDLHM-AEKTKLITQLRDAKNLIEQLEqdkgmviaetkrqmhETLEMKEEEIAQLRSRIKQMTT 418
Cdd:COG1196   217 ELKEELKELEAELLLLKLRELeAELEELEAELEELEAELEELE---------------AELAELEAELEELRLELEELEL 281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  419 QGEELREQkEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIektsEEERISLQQELSRVKQEVVDVMKK--SS 496
Cdd:COG1196   282 ELEEAQAE-EYELLAELARLEQDIARLEERRRELEERLEELEEELAEL----EEELEELEEELEELEEELEEAEEEleEA 356

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  497 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENK 576
Cdd:COG1196   357 EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  577 LRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVL 656
Cdd:COG1196   437 EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLL 516


                  ...
gi 530372328  657 KQQ 659
Cdd:COG1196   517 AGL 519
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 725-1048 6.82e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 6.82e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  725 LEEELSVLKDQTDKMK--QELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVE 802
Cdd:COG1196   198 LERQLEPLERQAEKAEryRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELE 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  803 NLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHK 882
Cdd:COG1196   278 ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  883 IQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVekenmILQMREGQKKEIEILTQKLSAKEDSIHI 962
Cdd:COG1196   358 AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE-----LEEAEEALLERLERLEEELEELEEALAE 432

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  963 LNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSR 1042
Cdd:COG1196   433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512


                  ....*.
gi 530372328 1043 LETNQK 1048
Cdd:COG1196   513 ALLLAG 518
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1469-2108 7.18e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 7.18e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1469 KKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDclkgEMEDDKSKMEKKESNLETELKSQTAR 1548
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE----EAQAEEYELLAELARLEQDIARLEER 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1549 IMELEDHITQKTIEIESLNEVLKNYNQQKD---IEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELET 1625
Cdd:COG1196   311 RRELEERLEELEEELAELEEELEELEEELEeleEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1626 KKKELehvnLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQykkgteSHLSELNTKLQE 1705
Cdd:COG1196   391 ALRAA----AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA------EEEAELEEEEEA 460

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1706 REREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETV 1785
Cdd:COG1196   461 LLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAAL 540

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1786 SSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGH---LQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQK 1862
Cdd:COG1196   541 EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRatfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGD 620

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1863 TLQEKELTCQILEQKIKELDSCLVRQKEVhRVEMEELtskyeklqalqqmdgrnkptelleenteekskshlvqpkllsn 1942
Cdd:COG1196   621 TLLGRTLVAARLEAALRRAVTLAGRLREV-TLEGEGG------------------------------------------- 656

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1943 meaqhNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMRE 2022
Cdd:COG1196   657 -----SAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 2023 FNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEK-------DDDLKRTAKRYEEildareeeMTAK 2095
Cdd:COG1196   732 AEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpvnllaIEEYEELEERYDF--------LSEQ 803

                         650
                  ....*....|...
gi 530372328 2096 VRDLQTQLEELQK 2108
Cdd:COG1196   804 REDLEEARETLEE 816
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1071-1866 7.42e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 7.42e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1071 KKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQK---------- 1140
Cdd:TIGR02168  203 KSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELrlevseleee 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1141 ----SAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEK 1216
Cdd:TIGR02168  283 ieelQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEE 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1217 SNKSLEDKSLEFKKLSEE-----------------LAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRT 1279
Cdd:TIGR02168  363 LEAELEELESRLEELEEQletlrskvaqlelqiasLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAEL 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1280 TKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEK 1359
Cdd:TIGR02168  443 EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGIL 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1360 ESCITQLKKE----------LSENINAVTLmkEELKEKKVEISSLSKQL--------------TDLNVQLQNSISLSEKE 1415
Cdd:TIGR02168  523 GVLSELISVDegyeaaieaaLGGRLQAVVV--ENLNAAKKAIAFLKQNElgrvtflpldsikgTEIQGNDREILKNIEGF 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1416 AAISSLRKQYDEEKCELLDQVQDLSFKVDTLsKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLElKSKE 1495
Cdd:TIGR02168  601 LGVAKDLVKFDPKLRKALSYLLGGVLVVDDL-DNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILE-RRRE 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1496 AYEKDEQINLLKEELDQQNKRFDCLKGE---MEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKN 1572
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAELRKEleeLEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1573 YNQQKDIEHKELVQKLQHFQELGEEKdnrvKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLE 1652
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEI----EELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIA 834

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1653 S--ESAAKLAELKRKAEQKIAAIKKQlLSQMEEKEEQYKKGTESHL---SELNTKLQEREREVHILEEKLKSVES--SQS 1725
Cdd:TIGR02168  835 AteRRLEDLEEQIEELSEDIESLAAE-IEELEELIEELESELEALLnerASLEEALALLRSELEELSEELRELESkrSEL 913

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1726 ETLIVPRSAKNVAAYTEQEEAdsqgcvqktyEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEmrcQYQERLIKLEHA 1805
Cdd:TIGR02168  914 RRELEELREKLAQLELRLEGL----------EVRIDNLQERLSEEYSLTLEEAEALENKIEDDEE---EARRRLKRLENK 980

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530372328  1806 EAKqhedqsmIGHLQ----EELEEKNKKYSLIVAQHVEKEGGKNNIQ---------AKQNLENVFDDVQKTLQE 1866
Cdd:TIGR02168  981 IKE-------LGPVNlaaiEEYEELKERYDFLTAQKEDLTEAKETLEeaieeidreARERFKDTFDQVNENFQR 1047
PTZ00121 PTZ00121
MAEBL; Provisional
 1412-1880 1.04e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.47  E-value: 1.04e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1412 SEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQiQLEL 1491
Cdd:PTZ00121 1286 AEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE-AAEE 1364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1492 KSKEAYEKDEQINLLKEELD---QQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARimeledhitqktieiESLNE 1568
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKADAAKkkaEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAK---------------KKAEE 1429

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1569 VLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQvysMKAELETKKKELEHVNLSVKSKEEELKALE 1648
Cdd:PTZ00121 1430 KKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAK---KKAEEAKKADEAKKKAEEAKKKADEAKKAA 1506

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1649 DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETL 1728
Cdd:PTZ00121 1507 EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEA 1586

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1729 --IVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQ-RNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHA 1805
Cdd:PTZ00121 1587 kkAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEE 1666

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530372328 1806 EAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKE 1880
Cdd:PTZ00121 1667 AKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEE 1741
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1483-2108 1.10e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.10e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1483 KELQIQLELKSKEAYEKdeQINLLKEELDQQNKRFDclkgEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIE 1562
Cdd:COG1196   216 RELKEELKELEAELLLL--KLRELEAELEELEAELE----ELEAELEELEAELAELEAELEELRLELEELELELEEAQAE 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1563 IESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDN---RVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKS 1639
Cdd:COG1196   290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAEleeELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1640 KEEELKALEDRLESESAAKLAELKRKAEQkiaaikKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKS 1719
Cdd:COG1196   370 AEAELAEAEEELEELAEELLEALRAAAEL------AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1720 VESSQSETLivprsaknvAAYTEQEEAdsqgcvqktyEEKISVLQRNLTEKEKLLQRVGQEKEETVSshfemrcqyqeRL 1799
Cdd:COG1196   444 LEEAAEEEA---------ELEEEEEAL----------LELLAELLEEAALLEAALAELLEELAEAAA-----------RL 493

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1800 IKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENvfDDVQKTLQEKELTCQILEQKIK 1879
Cdd:COG1196   494 LLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ--NIVVEDDEVAAAAIEYLKAAKA 571

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1880 ELDSCLVRQKEVHRVEMEELTSKYEKLQA--LQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGA 1957
Cdd:COG1196   572 GRATFLPLDKIRARAALAAALARGAIGAAvdLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTL 651

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1958 EREKQKLGKEIVRLQ-KDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEM 2036
Cdd:COG1196   652 EGEGGSAGGSLTGGSrRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530372328 2037 TIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEI----LDAREE--EMTAKVRDLQTQLEELQK 2108
Cdd:COG1196   732 AEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpvnLLAIEEyeELEERYDFLSEQREDLEE 809
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 339-955 1.17e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.17e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  339 EALQEQLDERLQELEKikdlhMAEKTklitqlRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTT 418
Cdd:COG1196   192 EDILGELERQLEPLER-----QAEKA------ERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEA 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  419 QGEELREQKEKsERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTS---EEERISLQQELSRVKQEVVDVmkKS 495
Cdd:COG1196   261 ELAELEAELEE-LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRrelEERLEELEEELAELEEELEEL--EE 337

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  496 SEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEksqseylkisQEKEQQESLALEELELQKKAILTESEN 575
Cdd:COG1196   338 ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEE----------LEELAEELLEALRAAAELAAQLEELEE 407

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  576 KLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAvHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQV 655
Cdd:COG1196   408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALE-EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  656 LKQQYQTEMEKlrekcEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKAR-HKLEEELSVLKD 734
Cdd:COG1196   487 AEAAARLLLLL-----EAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALqNIVVEDDEVAAA 561

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  735 QTDKMKQELEAKMDEqknhhqQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGE 814
Cdd:COG1196   562 AIEYLKAAKAGRATF------LPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  815 LQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEK 894
Cdd:COG1196   636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE 715

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530372328  895 QNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQM--REGQKKEIEILTQKLSA 955
Cdd:COG1196   716 RLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPpdLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1026-1911 1.34e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.00  E-value: 1.34e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1026 LEMAQANSAGISDAVSRLETN------QKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEiQLQEKEQEVAELK 1099
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlkslerQAEKAERYKELKAELRELELALLVLRLEELREELEELQE-ELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1100 QKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQL 1179
Cdd:TIGR02168  260 AELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1180 VELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQldicckktealleakTNELIN 1259
Cdd:TIGR02168  340 AELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL---------------NNEIER 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1260 ISSSktnaiLSRISHCQHRTTKVKEALLIKTctvseLEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLv 1339
Cdd:TIGR02168  405 LEAR-----LERLEDRRERLQQEIEELLKKL-----EEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA- 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1340 teKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEElkekkveisslsKQLTDLNVQLQNSISLSEK-EAAI 1418
Cdd:TIGR02168  474 --EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ------------SGLSGILGVLSELISVDEGyEAAI 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1419 SSLrkqydeekceLLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYE 1498
Cdd:TIGR02168  540 EAA----------LGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVK 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1499 KDEQINLLKEELDQQNKRFDCLKGEMEDDKSKmekkesnletelkSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKD 1578
Cdd:TIGR02168  610 FDPKLRKALSYLLGGVLVVDDLDNALELAKKL-------------RPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERR 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1579 IEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESaak 1658
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLS--- 753

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1659 lAELKRKAEQkiaaikKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETlivprsaknva 1738
Cdd:TIGR02168  754 -KELTELEAE------IEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL----------- 815

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1739 ayteQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGH 1818
Cdd:TIGR02168  816 ----NEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL 891

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1819 LQEELEEKNKKyslivaqhvEKEGGKNNIQAKQNLENvfddVQKTLQEKELTCQILEQKIKELdscLVRQKEVHRVEMEE 1898
Cdd:TIGR02168  892 LRSELEELSEE---------LRELESKRSELRRELEE----LREKLAQLELRLEGLEVRIDNL---QERLSEEYSLTLEE 955

                          890
                   ....*....|...
gi 530372328  1899 LTSKYEKLQALQQ 1911
Cdd:TIGR02168  956 AEALENKIEDDEE 968
PTZ00121 PTZ00121
MAEBL; Provisional
 278-805 1.59e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.09  E-value: 1.59e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  278 EVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKET---IQSHKEQCTLLTSEKEALQEQLDERLQELEK 354
Cdd:PTZ00121 1282 ELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAkkkADAAKKKAEEAKKAAEAAKAEAEAAADEAEA 1361

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  355 IKDLHMAEKTKLITQLRDAKNLIEQLEQDKGmviAETKRQMHETLEMKEEEIAQLRSRIKQmttqGEELREQKEKSERAa 434
Cdd:PTZ00121 1362 AEEKAEAAEKKKEEAKKKADAAKKKAEEKKK---ADEAKKKAEEDKKKADELKKAAAAKKK----ADEAKKKAEEKKKA- 1433

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  435 fEELEKALSTAQKTEEARRKlkAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARK 514
Cdd:PTZ00121 1434 -DEAKKKAEEAKKADEAKKK--AEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK 1510

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  515 EQELTKKLQTR----------EREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEA 584
Cdd:PTZ00121 1511 KADEAKKAEEAkkadeakkaeEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE 1590

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  585 ETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEM 664
Cdd:PTZ00121 1591 EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA 1670

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  665 EKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSvLKDQTDKMKQELE 744
Cdd:PTZ00121 1671 EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAK-KEAEEDKKKAEEA 1749

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530372328  745 AKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQL-ELLLKERDKHLKEHQAHVENLE 805
Cdd:PTZ00121 1750 KKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEdEKRRMEVDKKIKDIFDNFANII 1811
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 333-631 1.95e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.50  E-value: 1.95e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  333 LLTSEKEALQEQLDERLQELEKIkDLHMAEKTKLITQLRDAKNLIEQLEQDKGmviaETKRQMHETLEMKEEEIAQLRSR 412
Cdd:COG1196   236 ELEAELEELEAELEELEAELEEL-EAELAELEAELEELRLELEELELELEEAQ----AEEYELLAELARLEQDIARLEER 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  413 IKQMTTQGEELREQKEKSERAAfEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVM 492
Cdd:COG1196   311 RRELEERLEELEEELAELEEEL-EELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  493 KKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEylKISQEKEQQESLALEELELQKKAILTE 572
Cdd:COG1196   390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE--EEALEEAAEEEAELEEEEEALLELLAE 467

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 530372328  573 SENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMV 631
Cdd:COG1196   468 LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV 526
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 390-1009 1.95e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.50  E-value: 1.95e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  390 ETKRQMHETlemkEEEIAQLRSRIKQMTTQGEELREQKEKSERAAfeELEKALSTAQKTEEARRKLKAEMDEQIKTIEKT 469
Cdd:COG1196   176 EAERKLEAT----EENLERLEDILGELERQLEPLERQAEKAERYR--ELKEELKELEAELLLLKLRELEAELEELEAELE 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  470 SEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTkklQTREREFQEQMKVALEKSQSEyLKISQ 549
Cdd:COG1196   250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR---LEQDIARLEERRRELEERLEE-LEEEL 325

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  550 EKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEitv 629
Cdd:COG1196   326 AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL--- 402

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  630 mvEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEiifQAHIEEMNEKTLEKLDVKQTELE 709
Cdd:COG1196   403 --EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL---EEEEEALLELLAELLEEAALLEA 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  710 SLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSII----KEHEVSIQRTEKALKDQINQLEL 785
Cdd:COG1196   478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaAYEAALEAALAAALQNIVVEDDE 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  786 LLKERDKHLKEHQAH-VENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQV 864
Cdd:COG1196   558 VAAAAIEYLKAAKAGrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  865 AEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKK 944
Cdd:COG1196   638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530372328  945 EIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLldqeAKLKKELEN 1009
Cdd:COG1196   718 EEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL----ERLEREIEA 778
PTZ00121 PTZ00121
MAEBL; Provisional
 1449-2150 3.07e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 65.93  E-value: 3.07e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1449 EKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDK 1528
Cdd:PTZ00121 1224 KKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKK 1303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1529 SKMEKK---ESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEA 1605
Cdd:PTZ00121 1304 ADEAKKkaeEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAA 1383

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1606 EEKILTLENQVYSMKAELETKKK---------ELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAikkq 1676
Cdd:PTZ00121 1384 KKKAEEKKKADEAKKKAEEDKKKadelkkaaaAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKA---- 1459

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1677 llsqmeekEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTY 1756
Cdd:PTZ00121 1460 --------EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE 1531

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1757 EEKISVLQRNLTEKEKLLQrvgQEKEETVSSHFEMRCQYQERliklehaeaKQHEDQSMIGHLQEELEEKNKKYSLIVAQ 1836
Cdd:PTZ00121 1532 EAKKADEAKKAEEKKKADE---LKKAEELKKAEEKKKAEEAK---------KAEEDKNMALRKAEEAKKAEEARIEEVMK 1599

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1837 HVEKEGGKNNIQAKQNLENVF--DDVQKTLQEKELTCQILEQKIKEldsclVRQKEVHRVEMEELTSKYEKLQALQQMDG 1914
Cdd:PTZ00121 1600 LYEEEKKMKAEEAKKAEEAKIkaEELKKAEEEKKKVEQLKKKEAEE-----KKKAEELKKAEEENKIKAAEEAKKAEEDK 1674

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1915 RNKPTELLEENTEEKSKSHLVQpkllsnmeaqhndlEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEyd 1994
Cdd:PTZ00121 1675 KKAEEAKKAEEDEKKAAEALKK--------------EAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE-- 1738

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1995 qEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDL 2074
Cdd:PTZ00121 1739 -AEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEG 1817

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530372328 2075 KRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNTQLAQKTTLISD--SKLKEQEFREQIHN 2150
Cdd:PTZ00121 1818 NLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDdeEEIEEADEIEKIDK 1895
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 310-1102 3.14e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 3.14e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   310 VKRQENLLKRCKETIQSHKE--------QCTLLTSEKEALQEQLDERLQELEKikdlhmaektkLITQLRDAKNLIEQLE 381
Cdd:TIGR02168  198 LERQLKSLERQAEKAERYKElkaelrelELALLVLRLEELREELEELQEELKE-----------AEEELEELTAELQELE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   382 QDkgmvIAETKRQMHEtlemKEEEIAQLRSRIKQMTTQGEELREQKE--KSERAAFEELEKALSTAQKTEEARRKLKAEM 459
Cdd:TIGR02168  267 EK----LEELRLEVSE----LEEEIEELQKELYALANEISRLEQQKQilRERLANLERQLEELEAQLEELESKLDELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   460 DEQIKTIEKTSEEERISLQQELSRVKQEVVDvmkksSEEQIAKLQKLHEKelARKEQELTKKLQTREREFQEQMKVALEK 539
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEE-----LESRLEELEEQLET--LRSKVAQLELQIASLNNEIERLEARLER 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   540 SQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLavhleAE 619
Cdd:TIGR02168  412 LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEREL-----AQ 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   620 KNKHNKEITVMVEKHKTELESLKHQQDALWTEK--LQVLKQQYQTEmeklrEKCEQEKETLL---------KDKEIIFQA 688
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKALLKNQSGLSgiLGVLSELISVD-----EGYEAAIEAALggrlqavvvENLNAAKKA 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   689 hIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQ----------------ELEAKMDEQKN 752
Cdd:TIGR02168  562 -IAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllggvlvvdDLDNALELAKK 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   753 HHQQ----------------------QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHqahvENLEADIKR 810
Cdd:TIGR02168  641 LRPGyrivtldgdlvrpggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL----EELEEELEQ 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   811 SEGELQQASAKLdvfqsyqSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQ 890
Cdd:TIGR02168  717 LRKELEELSRQI-------SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   891 QLEKQNSEMEQKVKSLtqvyeSKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETK 970
Cdd:TIGR02168  790 QIEQLKEELKALREAL-----DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   971 FKNQEKKMEKVK--QKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSagisdAVSRLETNQK 1048
Cdd:TIGR02168  865 EELIEELESELEalLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLEL-----RLEGLEVRID 939

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....
gi 530372328  1049 EQIESLTEVHRRELndvisiwekklnQQAEELQEIHEIQLQEKEQEVAELKQKI 1102
Cdd:TIGR02168  940 NLQERLSEEYSLTL------------EEAEALENKIEDDEEEARRRLKRLENKI 981
PTZ00121 PTZ00121
MAEBL; Provisional
 338-1065 7.48e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.78  E-value: 7.48e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  338 KEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNL--IEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQ 415
Cdd:PTZ00121 1173 EDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEErkAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNE 1252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  416 MTTQGEELREQKEKSERAAF--------EELEKAlSTAQKTEEARrklKAEMDEQIKTIEKTSEEERislqqELSRVKQE 487
Cdd:PTZ00121 1253 EIRKFEEARMAHFARRQAAIkaeearkaDELKKA-EEKKKADEAK---KAEEKKKADEAKKKAEEAK-----KADEAKKK 1323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  488 VVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKlqtrEREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK 567
Cdd:PTZ00121 1324 AEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAD----EAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKK 1399

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  568 AiltESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKdlavhleAEKNKHNKEITVMVEKHKTELESLKHQQDA 647
Cdd:PTZ00121 1400 A---EEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKK-------AEEAKKADEAKKKAEEAKKAEEAKKKAEEA 1469

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  648 LWTEKLQVlKQQYQTEMEKLREKCEQEKEtllKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEE 727
Cdd:PTZ00121 1470 KKADEAKK-KAEEAKKADEAKKKAEEAKK---KADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEK 1545

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  728 ELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKehQAHVENLEAD 807
Cdd:PTZ00121 1546 KKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAK--KAEEAKIKAE 1623

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  808 IKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQV--AEVEAQKKDVCTELDAHKIQV 885
Cdd:PTZ00121 1624 ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAkkAEEDEKKAAEALKKEAEEAKK 1703

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  886 QDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEkenmiLQMREGQKKEIEILTQKLSAKEDSIHI--- 962
Cdd:PTZ00121 1704 AEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEE-----AKKDEEEKKKIAHLKKEEEKKAEEIRKeke 1778

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  963 ------LNEEYETKFKNQEKKMEKVKQKAKEMQE---------TLKKKLLDQEAKLKKELENTALELSQKEKQ--FNAKM 1025
Cdd:PTZ00121 1779 avieeeLDEEDEKRRMEVDKKIKDIFDNFANIIEggkegnlviNDSKEMEDSAIKEVADSKNMQLEEADAFEKhkFNKNN 1858

                         730       740       750       760
                  ....*....|....*....|....*....|....*....|
gi 530372328 1026 LEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDV 1065
Cdd:PTZ00121 1859 ENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDI 1898
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 732-1526 8.22e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.69  E-value: 8.22e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   732 LKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHE---VSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADI 808
Cdd:TIGR02168  218 LKAELRELELALLVLRLEELREELEELQEELKEAEeelEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   809 KRSEGELQQASAKLDvfqsyqsATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDL 888
Cdd:TIGR02168  298 SRLEQQKQILRERLA-------NLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEEL 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   889 MQQLEKQNSEMEQKVKSLTQVYEsKLEDGNKEQE----QTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILN 964
Cdd:TIGR02168  371 ESRLEELEEQLETLRSKVAQLEL-QIASLNNEIErleaRLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   965 EEYETKFKNQEKKMEKVKQKAKEMQETLkKKLLDQEAKLKKELENTALELSQKEK-QFNAKMLEMAQANSAGISDAVSRL 1043
Cdd:TIGR02168  450 EELQEELERLEEALEELREELEEAEQAL-DAAERELAQLQARLDSLERLQENLEGfSEGVKALLKNQSGLSGILGVLSEL 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1044 ETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE-------------ELQEIHEIQLQEKEQEVAELKQKILLFGCEKE 1110
Cdd:TIGR02168  529 ISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAflkqnelgrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLV 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1111 EMNKEIT-----WLkeEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHleklEVDLNKSLKENTFLQEQLVELKML 1185
Cdd:TIGR02168  609 KFDPKLRkalsyLL--GGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPG----GVITGGSAKTNSSILERRREIEEL 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1186 AEEDKR---KVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLdiccKKTEALLEAKTNELINISS 1262
Cdd:TIGR02168  683 EEKIEEleeKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLE----AEVEQLEERIAQLSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1263 SktnailsrishcQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEK 1342
Cdd:TIGR02168  759 L------------EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1343 EALQKEGGNQQQAASEkescITQLKKELSENINAVTLmkeelkekkvEISSLSKQLTDLNVQLQ-NSISLSEKEAAISSL 1421
Cdd:TIGR02168  827 ESLERRIAATERRLED----LEEQIEELSEDIESLAA----------EIEELEELIEELESELEaLLNERASLEEALALL 892

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1422 RKQYDeekcELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKA---QSRFTQHQNTVKELQIQLELKSKEAYE 1498
Cdd:TIGR02168  893 RSELE----ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIdnlQERLSEEYSLTLEEAEALENKIEDDEE 968

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 530372328  1499 K-DEQINLLK--------------EELDQQNKRFDCLKGEMED 1526
Cdd:TIGR02168  969 EaRRRLKRLEnkikelgpvnlaaiEEYEELKERYDFLTAQKED 1011
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 762-1509 7.17e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.24  E-value: 7.17e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   762 IKEHEVSIQRTEK---ALKDQINQLELLLKERDKHLKEHQAHVENLEADIKR-SEGELQQASAKLDVFQSYQSATHEQTK 837
Cdd:TIGR02169  232 KEALERQKEAIERqlaSLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDlGEEEQLRVKEKIGELEAEIASLERSIA 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   838 AYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSL------TQVYE 911
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFaetrdeLKDYR 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   912 SKLEDGNKEQEQTKQILVEKENMILQMREgqkkEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQkAKEMQET 991
Cdd:TIGR02169  392 EKLEKLKREINELKRELDRLQEELQRLSE----ELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQ-LAADLSK 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   992 LKKKLLDQEA---KLKKELENTALELSQKEKQ---------FNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHR 1059
Cdd:TIGR02169  467 YEQELYDLKEeydRVEKELSKLQRELAEAEAQaraseervrGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAG 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1060 RELNDVISIWEKKLNQQAEELQE----------IHEIQLQEKEQEVAELKQKIL----LFGCEKEEMNKEITWLKEEGVK 1125
Cdd:TIGR02169  547 NRLNNVVVEDDAVAKEAIELLKRrkagratflpLNKMRDERRDLSILSEDGVIGfavdLVEFDPKYEPAFKYVFGDTLVV 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1126 QDTT----------LNELQEQLKQKSAHV-------NSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEE 1188
Cdd:TIGR02169  627 EDIEaarrlmgkyrMVTLEGELFEKSGAMtggsrapRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDE 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1189 DKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELA---IQLDICCKKTEALLEAKTNELINISSSKT 1265
Cdd:TIGR02169  707 LSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEnvkSELKELEARIEELEEDLHKLEEALNDLEA 786

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1266 NAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEAL 1345
Cdd:TIGR02169  787 RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEEL 866

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1346 QKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNsisLSEKEAAISSLRKQY 1425
Cdd:TIGR02169  867 EEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEA---LEEELSEIEDPKGED 943

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1426 DEEKCELLDqVQDLSFKVDTLsKEKISALEQVDdwsNKFSEWKKKAQSRFtqhqNTVKELQIQLELKSKEAYEKDEQINL 1505
Cdd:TIGR02169  944 EEIPEEELS-LEDVQAELQRV-EEEIRALEPVN---MLAIQEYEEVLKRL----DELKEKRAKLEEERKAILERIEEYEK 1014


                   ....
gi 530372328  1506 LKEE 1509
Cdd:TIGR02169 1015 KKRE 1018
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 337-1204 7.55e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.53  E-value: 7.55e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   337 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETkrqmheTLEMKEEEIAQLRSRIKQM 416
Cdd:pfam02463  171 KKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEY------LLYLDYLKLNEERIDLLQE 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   417 TTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSS 496
Cdd:pfam02463  245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   497 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKS--QSEYLKISQEKEQQESLALEELELQKKAILTESE 574
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLeqLEEELLAKKKLESERLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   575 NKLRDLQQEAETYRTRILELESSLEKSLQENKnqskdLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQ 654
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEE-----ESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQL 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   655 VLKQQYQTEMEKLREkcEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKD 734
Cdd:pfam02463  480 VKLQEQLELLLSRQK--LEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATA 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   735 QTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGE 814
Cdd:pfam02463  558 DEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   815 LQQASAKLDVFQSYQSATHEQTkayEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEK 894
Cdd:pfam02463  638 KESAKAKESGLRKGVSLEEGLA---EKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKK 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   895 QNSEMEQKVKSLTQVYESKL-EDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKN 973
Cdd:pfam02463  715 LKLEAEELLADRVQEAQDKInEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEE 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   974 QEKKMEKVKQKAKEmqetlKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIES 1053
Cdd:pfam02463  795 KLKAQEEELRALEE-----ELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELL 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1054 LTEVHRRELNDVISIWEKKLNQQAEELQEIHE-IQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNE 1132
Cdd:pfam02463  870 QELLLKEEELEEQKLKDELESKEEKEKEEKKElEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKE 949

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530372328  1133 LQEQLKQKSAHVNSLAQDEtklKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTD 1204
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLA---KEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1466-2105 9.33e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.85  E-value: 9.33e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1466 EWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKgEMEDDKSKMEKKESNLETELKSQ 1545
Cdd:PRK03918  179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELE-ELKEEIEELEKELESLEGSKRKL 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1546 TARIMELEDHITQKTIEIESLNEVLKNYNQQKdiEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELET 1625
Cdd:PRK03918  258 EEKIRELEERIEELKKEIEELEEKVKELKELK--EKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEE 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1626 KKKELEHVNLSVKSKEEELKALEDRLES-ESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQ 1704
Cdd:PRK03918  336 KEERLEELKKKLKELEKRLEELEERHELyEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIG 415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1705 EREREVHILEEKLKSVESSQSETLIVPRSaknvaaYTEQEEADsqgcVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEEt 1784
Cdd:PRK03918  416 ELKKEIKELKKAIEELKKAKGKCPVCGRE------LTEEHRKE----LLEEYTAELKRIEKELKEIEEKERKLRKELRE- 484

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1785 vsshFEMRCQYQERLIKL-EHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGG----KNNIQAKQNLENVFDD 1859
Cdd:PRK03918  485 ----LEKVLKKESELIKLkELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEikslKKELEKLEELKKKLAE 560

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1860 VQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLqalqqmdgrnkptelleenteekskshlvqpkl 1939
Cdd:PRK03918  561 LEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLEL--------------------------------- 607

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1940 lSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEhqqeLEILKKEYDQEREEKIKQEQEDLELKHNSTLKQL 2019
Cdd:PRK03918  608 -KDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKE----LEELEKKYSEEEYEELREEYLELSRELAGLRAEL 682

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 2020 mrefntqlaqkeqelemtiketinkaqeveaELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDARE--EEMTAKVR 2097
Cdd:PRK03918  683 -------------------------------EELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALErvEELREKVK 731


                  ....*...
gi 530372328 2098 DLQTQLEE 2105
Cdd:PRK03918  732 KYKALLKE 739
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1940-2160 9.68e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.72  E-value: 9.68e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1940 LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQL 2019
Cdd:COG1196   269 LEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEE 348

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 2020 MREFNTQLAQKEQELEMTIKETINKAQEVEAElLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDL 2099
Cdd:COG1196   349 AEEELEEAEAELAEAEEALLEAEAELAEAEEE-LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530372328 2100 QTQLEELQKKYQQKLEQEENPGNDNTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEK 2160
Cdd:COG1196   428 EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 321-640 1.12e-08

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 60.52  E-value: 1.12e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   321 KETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQ----LEQDKGMVIAETKRQMH 396
Cdd:pfam17380  281 QKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQermaMERERELERIRQEERKR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   397 ETLEMKEEEIAQLRSRIKQMttqgEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKaemdEQIKTIEKTSEEERIS 476
Cdd:pfam17380  361 ELERIRQEEIAMEISRMREL----ERLQMERQQKNERVRQELEAARKVKILEEERQRKIQ----QQKVEMEQIRAEQEEA 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   477 LQQELSRVKQEVVDVMKKSSEEQIAK---LQKLHEKELARKEQELTKKLQTRER-EFQEQMKVALEKSQSEYLKISQEKE 552
Cdd:pfam17380  433 RQREVRRLEEERAREMERVRLEEQERqqqVERLRQQEEERKRKKLELEKEKRDRkRAEEQRRKILEKELEERKQAMIEEE 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   553 QQESLALEELELQKKAILTESEnklrdlQQEAETYRTRILELESslEKSLQENKNQSKDLAVHLEA-EKNKHNKEITVMV 631
Cdd:pfam17380  513 RKRKLLEKEMEERQKAIYEEER------RREAEEERRKQQEMEE--RRRIQEQMRKATEERSRLEAmEREREMMRQIVES 584


                   ....*....
gi 530372328   632 EKHKTELES 640
Cdd:pfam17380  585 EKARAEYEA 593
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 877-1705 1.63e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.08  E-value: 1.63e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   877 ELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYEsKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAK 956
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQLE-RLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   957 EDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQAnSAGI 1036
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDA-EERL 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1037 SDAVSRLEtNQKEQIESLTE------VHRRELNDVISIWEKKLNQQAEELQEIhEIQLQEKEQEVAELKQKILLFGCEKE 1110
Cdd:TIGR02169  325 AKLEAEID-KLLAEIEELEReieeerKRRDKLTEEYAELKEELEDLRAELEEV-DKEFAETRDELKDYREKLEKLKREIN 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1111 EMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLnkslkentflqEQLVELKMLAEEDK 1190
Cdd:TIGR02169  403 ELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKL-----------EQLAADLSKYEQEL 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1191 RKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAI-- 1268
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLnn 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1269 ----------------------------LSRISHCQHRTTKVKEALLI----------------------KTCTVSELEA 1298
Cdd:TIGR02169  552 vvveddavakeaiellkrrkagratflpLNKMRDERRDLSILSEDGVIgfavdlvefdpkyepafkyvfgDTLVVEDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1299 ------QLRQLTEEQNTL----------NISFQQATHQLEEKEnQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESC 1362
Cdd:TIGR02169  632 arrlmgKYRMVTLEGELFeksgamtggsRAPRGGILFSRSEPA-ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1363 ITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSIS--------LSEKEAAISSLRKQ----YDEEKC 1430
Cdd:TIGR02169  711 LSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSelkelearIEELEEDLHKLEEAlndlEARLSH 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1431 ELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEEL 1510
Cdd:TIGR02169  791 SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKE----IQELQEQRIDLKEQIKSIEKEIENLNGKKEEL 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1511 DQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDiehkelvqklqh 1590
Cdd:TIGR02169  867 EEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELS------------ 934

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1591 fqELGEEKDNRVKEAEEkILTLEnQVYSMKAELETKKKELEHVNlsvkskeeeLKALEDRleSESAAKLAELKRKaEQKI 1670
Cdd:TIGR02169  935 --EIEDPKGEDEEIPEE-ELSLE-DVQAELQRVEEEIRALEPVN---------MLAIQEY--EEVLKRLDELKEK-RAKL 998

                          890       900       910
                   ....*....|....*....|....*....|....*
gi 530372328  1671 AAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQE 1705
Cdd:TIGR02169  999 EEERKAILERIEEYEKKKREVFMEAFEAINENFNE 1033
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 699-1372 2.97e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 2.97e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   699 EKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQvdSIIKEHEVSIQRTEKALKD 778
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI--SRLEQQKQILRERLANLER 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   779 QINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERI 858
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   859 LLTKQVAEVEAQKKD-------------------VCTELDAHKIQVQDLMQQLEK---QNSEMEQKVKSLTQVYESKLE- 915
Cdd:TIGR02168  397 SLNNEIERLEARLERledrrerlqqeieellkklEEAELKELQAELEELEEELEElqeELERLEEALEELREELEEAEQa 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   916 -DGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKfKNQEKKMEKV------------K 982
Cdd:TIGR02168  477 lDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVD-EGYEAAIEAAlggrlqavvvenL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   983 QKAKEMQETLKKKLLDQEAKL------KKELENTALELSQKEKQFNAKMLEMAQANSAgISDAVS------RLETNQKEQ 1050
Cdd:TIGR02168  556 NAAKKAIAFLKQNELGRVTFLpldsikGTEIQGNDREILKNIEGFLGVAKDLVKFDPK-LRKALSyllggvLVVDDLDNA 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1051 IESLTEVHRRE----LNDVISIWEKKLNQQAEElqeiHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEgvkq 1126
Cdd:TIGR02168  635 LELAKKLRPGYrivtLDGDLVRPGGVITGGSAK----TNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE---- 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1127 dttLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEE 1206
Cdd:TIGR02168  707 ---LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1207 FQSLKSSHEKSNKSLEDKSLEFKKLSEELaiqldicckktealleAKTNELINISSSKTNAILSRISHCQHRTTKVKEAL 1286
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAEL----------------TLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1287 LIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQL 1366
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL 927


                   ....*.
gi 530372328  1367 KKELSE 1372
Cdd:TIGR02168  928 ELRLEG 933
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 673-1210 3.77e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.79  E-value: 3.77e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  673 QEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQtelESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKmDEQKN 752
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELEELEAEL---EELEAELEELEAELAELEAELEELRLELEELELELEEA-QAEEY 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  753 HHQQQVDSIIKEHEVSIQRtEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSAT 832
Cdd:COG1196   292 ELLAELARLEQDIARLEER-RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  833 HEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYES 912
Cdd:COG1196   371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  913 KLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEIltQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKE----- 987
Cdd:COG1196   451 EAELEEEEEALLELLAELLEEAALLEAALAELLEEL--AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAgavav 528

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  988 ------------------------MQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGI----SDA 1039
Cdd:COG1196   529 ligveaayeaaleaalaaalqnivVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVdlvaSDL 608

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1040 VSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWL 1119
Cdd:COG1196   609 READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1120 KEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSK 1199
Cdd:COG1196   689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768

                         570
                  ....*....|.
gi 530372328 1200 LKTTDEEFQSL 1210
Cdd:COG1196   769 LERLEREIEAL 779
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2187-2230 5.86e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 50.68  E-value: 5.86e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 530372328   2187 PTEFEYLRKVLFEYMMGRET--KTMAKVITTVLKFPDDQTQKILER 2230
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 309-702 7.38e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.14  E-value: 7.38e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   309 RVKRQENLLKRCKEtIQSHKEQCTLLTSEKEALQEQLDE---RLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKG 385
Cdd:TIGR02168  665 SAKTNSSILERRRE-IEELEEKIEELEEKIAELEKALAElrkELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE 743

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   386 MViAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSEraafEELEKALSTAQKTEEARRKLKAEM-DEQIK 464
Cdd:TIGR02168  744 QL-EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELE----AQIEQLKEELKALREALDELRAELtLLNEE 818

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   465 TIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEkelarkeqeltkKLQTREREFQEQMKVALEKSQSEY 544
Cdd:TIGR02168  819 AANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE------------ELEELIEELESELEALLNERASLE 886

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   545 LKISQEKEQQESLALEELELQKKAilTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHN 624
Cdd:TIGR02168  887 EALALLRSELEELSEELRELESKR--SELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIE 964

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530372328   625 KEItvmvEKHKTELESLKHQQDALWTEKLQVLkQQYQTEMEKLREKcEQEKETLLKDKEIIFQAhIEEMNEKTLEKLD 702
Cdd:TIGR02168  965 DDE----EEARRRLKRLENKIKELGPVNLAAI-EEYEELKERYDFL-TAQKEDLTEAKETLEEA-IEEIDREARERFK 1035
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1575-2157 1.23e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.25  E-value: 1.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1575 QQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESE 1654
Cdd:COG1196   221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1655 SAAK--LAELKRKAEQKIAAIKKQLLSQMEEKEEQykkgtESHLSELNTKLQEREREVHILEEKLKSVESSQSETL--IV 1730
Cdd:COG1196   301 EQDIarLEERRRELEERLEELEEELAELEEELEEL-----EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEaeLA 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1731 PRSAKNVAAYTEQEEADSQgcvQKTYEEKISVLQRNLTEKEKLLQRVGQEKEEtvsshfemrcQYQERLIKLEHAEAKQH 1810
Cdd:COG1196   376 EAEEELEELAEELLEALRA---AAELAAQLEELEEAEEALLERLERLEEELEE----------LEEALAELEEEEEEEEE 442

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1811 EDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDScLVRQKE 1890
Cdd:COG1196   443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALL-LAGLRG 521

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1891 VHRVEMEELTSKYEKLQALQQMDGRnkptelleenteekskshLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVR 1970
Cdd:COG1196   522 LAGAVAVLIGVEAAYEAALEAALAA------------------ALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR 583

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1971 LQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEA 2050
Cdd:COG1196   584 ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 2051 ELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNTQLAQK 2130
Cdd:COG1196   664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743

                         570       580       590
                  ....*....|....*....|....*....|....*
gi 530372328 2131 TTLIS--------DSKLKEQEFREQIHNLEDRLKK 2157
Cdd:COG1196   744 EEELLeeealeelPEPPDLEELERELERLEREIEA 778
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 390-1148 2.17e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 56.61  E-value: 2.17e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   390 ETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERaaFEELEKALSTAQKTEEARRKLKAEmdEQIKTIEKt 469
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--YQALLKEKREYEGYELLKEKEALE--RQKEAIER- 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   470 seeERISLQQELSRVKQEVVDVMKKSseEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQmkVALEKSQSEYLKISQ 549
Cdd:TIGR02169  245 ---QLASLEEELEKLTEEISELEKRL--EEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAE--IASLERSIAEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   550 EKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKeitv 629
Cdd:TIGR02169  318 EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREK---- 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   630 mVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEME---KLREKCEQEKETLLKDKEIifqAHIEEMNEKTLEKLDVKQT 706
Cdd:TIGR02169  394 -LEKLKREINELKRELDRLQEELQRLSEELADLNAAiagIEAKINELEEEKEDKALEI---KKQEWKLEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   707 ELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQ------QVDSIIKEHEVSIQRTEKALKDQI 780
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASiqgvhgTVAQLGSVGERYATAIEVAAGNRL 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   781 NQL----ELLLKERDKHLKEHQA-----------HVENLEADIKRSEGELQQASAKLDVFQSYQSATH------------ 833
Cdd:TIGR02169  550 NNVvvedDAVAKEAIELLKRRKAgratflplnkmRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKyvfgdtlvvedi 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   834 EQTKAYEEQLAQLQQKLLDLE----------TERILLTKQVAEvEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKv 903
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEksgamtggsrAPRGGILFSRSE-PAELQRLRERLEGLKRELSSLQSELRRIENRLDEL- 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   904 KSLTQVYESKLEDGNKEQEQtkqilvekenmILQMREGQKKEIEILTQKLSAKEDSIhilneeyetkfKNQEKKMEKVKQ 983
Cdd:TIGR02169  708 SQELSDASRKIGEIEKEIEQ-----------LEQEEEKLKERLEELEEDLSSLEQEI-----------ENVKSELKELEA 765

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   984 KAKEMQETLKKkLLDQEAKLKKELENTALELSQKEKQfnaKMLEMAQANSAGISDAVSRLetNQKEQIESLTEVHRRELN 1063
Cdd:TIGR02169  766 RIEELEEDLHK-LEEALNDLEARLSHSRIPEIQAELS---KLEEEVSRIEARLREIEQKL--NRLTLEKEYLEKEIQELQ 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1064 DVISIWEKKLNQQAEELQEIhEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAH 1143
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENL-NGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKR 918


                   ....*
gi 530372328  1144 VNSLA 1148
Cdd:TIGR02169  919 LSELK 923
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
303-540 2.47e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.46  E-value: 2.47e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  303 LETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQ------------EQLDERLQELEKikDLHMAEKT-----K 365
Cdd:COG4913   612 LAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlaeyswdeidvASAEREIAELEA--ELERLDASsddlaA 689

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  366 LITQLRDAKNLIEQLEQDKGMVIAETKRqmhetlemKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTA 445
Cdd:COG4913   690 LEEQLEELEAELEELEEELDELKGEIGR--------LEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGD 761

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  446 QKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVM--KKSSEEQIAKLQKLHEKELARKEQELTKKLQ 523
Cdd:COG4913   762 AVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDadLESLPEYLALLDRLEEDGLPEYEERFKELLN 841

                         250
                  ....*....|....*..
gi 530372328  524 TREREFQEQMKVALEKS 540
Cdd:COG4913   842 ENSIEFVADLLSKLRRA 858
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1282-2133 3.72e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.84  E-value: 3.72e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1282 VKEALLIKTCTVSELEAQLRQLTEEQNTLnISFQQATHQLEEKENQIKSmkADIESLVTEKEALQKEggnqqqaASEKES 1361
Cdd:TIGR02169  182 VEENIERLDLIIDEKRQQLERLRREREKA-ERYQALLKEKREYEGYELL--KEKEALERQKEAIERQ-------LASLEE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1362 CITQLKKELSENinavtlmKEELKEKKVEISSLSKQLTDLNVQLQNSIS--LSEKEAAISSLRKQYDEEKcellDQVQDL 1439
Cdd:TIGR02169  252 ELEKLTEEISEL-------EKRLEEIEQLLEELNKKIKDLGEEEQLRVKekIGELEAEIASLERSIAEKE----RELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1440 SFKVDTLSKEKISALEQVDDWSNKFSEWKKkaqsRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDC 1519
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELEREIEEERK----RRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1520 LKGEMEDdkskMEKKESNLETELKSQTARIMELEdhitqktieieslnevlknyNQQKDIEhkelvQKLQHFQELGEEKD 1599
Cdd:TIGR02169  397 LKREINE----LKRELDRLQEELQRLSEELADLN--------------------AAIAGIE-----AKINELEEEKEDKA 447

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1600 NRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLeseSAAKLAELKRKAEQKIAAIKKQ--- 1676
Cdd:TIGR02169  448 LEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA---RASEERVRGGRAVEEVLKASIQgvh 524

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1677 -LLSQMEEKEEQYKKGTESHLS-ELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSaknvaayteqeeADSQGCVQK 1754
Cdd:TIGR02169  525 gTVAQLGSVGERYATAIEVAAGnRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKM------------RDERRDLSI 592

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1755 TYEEKISVLQRNLTEKEKLLQRVgqekeetvsshfeMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNkkySLIV 1834
Cdd:TIGR02169  593 LSEDGVIGFAVDLVEFDPKYEPA-------------FKYVFGDTLVVEDIEAARRLMGKYRMVTLEGELFEKS---GAMT 656

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1835 AQHVEKEGGKNNiqakqnlenvfddvQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSkyeKLQALQQMDG 1914
Cdd:TIGR02169  657 GGSRAPRGGILF--------------SRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ---ELSDASRKIG 719

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1915 RNKPTELLEENTEEKSKshlvqpKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKehqqELEILKKEYD 1994
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLK------ERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEE----ALNDLEARLS 789

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1995 QEREEKIKQEQEDLELKHNSTLKQLmREFNTQLAQKEQELEMTIKETINKAQEVEA--ELLESHQEETNQLLKKIAEKDD 2072
Cdd:TIGR02169  790 HSRIPEIQAELSKLEEEVSRIEARL-REIEQKLNRLTLEKEYLEKEIQELQEQRIDlkEQIKSIEKEIENLNGKKEELEE 868

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530372328  2073 DLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKKYQQ-KLEQEENPGNDNTQLAQKTTL 2133
Cdd:TIGR02169  869 ELEELEAALRD-LESRLGDLKKERDELEAQLRELERKIEElEAQIEKKRKRLSELKAKLEAL 929
PTZ00121 PTZ00121
MAEBL; Provisional
 1568-2161 3.85e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.92  E-value: 3.85e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1568 EVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKAL 1647
Cdd:PTZ00121 1167 EEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAE 1246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1648 EDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEE--KEEQYKKGTESHLSELNTKLQEREREVhilEEKLKSVESSQS 1725
Cdd:PTZ00121 1247 EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADElkKAEEKKKADEAKKAEEKKKADEAKKKA---EEAKKADEAKKK 1323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1726 ETlivPRSAKNVAAYTEQEEADSQGCVQKTYEEKisvlQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHA 1805
Cdd:PTZ00121 1324 AE---EAKKKADAAKKKAEEAKKAAEAAKAEAEA----AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA 1396

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1806 EAKQHEDQSMIGHLQEELEEKNKKYSLivAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCL 1885
Cdd:PTZ00121 1397 KKKAEEDKKKADELKKAAAAKKKADEA--KKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADE 1474

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1886 VRQKEVHRVEMEELTSKYEklQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLG 1965
Cdd:PTZ00121 1475 AKKKAEEAKKADEAKKKAE--EAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK 1552

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1966 K-EIVRLQKDLRMLRKEHQQE---------LEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELE 2035
Cdd:PTZ00121 1553 KaEELKKAEEKKKAEEAKKAEedknmalrkAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEK 1632

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 2036 MTIKETINKAQE--VEAELLESHQEETNQLLKKIAEKDDDLKRTAkryEEILDAREEEMTAKVRDLQTQLEELQKKYQQK 2113
Cdd:PTZ00121 1633 KKVEQLKKKEAEekKKAEELKKAEEENKIKAAEEAKKAEEDKKKA---EEAKKAEEDEKKAAEALKKEAEEAKKAEELKK 1709

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*...
gi 530372328 2114 LEQEENPGNDNTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKN 2161
Cdd:PTZ00121 1710 KEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKK 1757
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1510-2035 9.17e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 54.28  E-value: 9.17e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1510 LDQQNKRFDCLKGEMEDDKSK-MEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDiEHKELVQKL 1588
Cdd:PRK02224  182 LSDQRGSLDQLKAQIEEKEEKdLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERRE-ELETLEAEI 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1589 QHFQEL-------GEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLEsESAAKLAE 1661
Cdd:PRK02224  261 EDLRETiaetereREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLE-ECRVAAQA 339

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1662 LKRKAEQKIAAIKkQLLSQMEEKEEQYKKgTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYT 1741
Cdd:PRK02224  340 HNEEAESLREDAD-DLEERAEELREEAAE-LESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEEL 417

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1742 EQEEADSQGCVqKTYEEKISVLQRNLTEKEKLLQ-----RVGQEKEEtvSSHFEMRCQYQERLIKLEhAEAKQHEDQsmi 1816
Cdd:PRK02224  418 REERDELRERE-AELEATLRTARERVEEAEALLEagkcpECGQPVEG--SPHVETIEEDRERVEELE-AELEDLEEE--- 490

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1817 ghlQEELEEKNKKYSLIVAQHVEKEGGKNNiqaKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEM 1896
Cdd:PRK02224  491 ---VEEVEERLERAEDLVEAEDRIERLEER---REDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAE 564

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1897 EELTSKYEKLQALQQMDGRNKPTELleenteekskshlvqpkllsnmeaQHNDLEFKLAGAErekqKLGKEIVRLQKdlr 1976
Cdd:PRK02224  565 EEAEEAREEVAELNSKLAELKERIE------------------------SLERIRTLLAAIA----DAEDEIERLRE--- 613

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 530372328 1977 mlRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELE 2035
Cdd:PRK02224  614 --KREALAELNDERRERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLD 670
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 435-1239 9.58e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.59  E-value: 9.58e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   435 FEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARK 514
Cdd:pfam02463  159 EEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEER 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   515 EQELTKKLQTREREF----------QEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEA 584
Cdd:pfam02463  239 IDLLQELLRDEQEEIesskqeiekeEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   585 ETYRTRILELESSLEKSLQENKNQSKDLavhLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEM 664
Cdd:pfam02463  319 SEKEKKKAEKELKKEKEEIEELEKELKE---LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   665 EKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELE 744
Cdd:pfam02463  396 ELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLK 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   745 AKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKrsegelqQASAKLDV 824
Cdd:pfam02463  476 ETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN-------YKVAISTA 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   825 FQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTK-QVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKV 903
Cdd:pfam02463  549 VIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKlKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGI 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   904 KSLTqvYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQ 983
Cdd:pfam02463  629 LKDT--ELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   984 KAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQ-FNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRREL 1062
Cdd:pfam02463  707 REKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQkIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKL 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1063 NDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCE---KEEMNKEITWLKEEGVKQDTTLNELQEQLKQ 1139
Cdd:pfam02463  787 KVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEeelEELALELKEEQKLEKLAEEELERLEEEITKE 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1140 KSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTfLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNK 1219
Cdd:pfam02463  867 ELLQELLLKEEELEEQKLKDELESKEEKEKEEKK-ELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEA 945

                          810       820
                   ....*....|....*....|
gi 530372328  1220 SLEDKSLEFKKLSEELAIQL 1239
Cdd:pfam02463  946 DEKEKEENNKEEEEERNKRL 965
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 158-474 1.77e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.53  E-value: 1.77e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   158 KEQLIQRLRRMERSLSSYRGKYSElvtAYQMLqREKKKLQGILSQSQDKSLRRIAELREELQMDQQ---AKKHLQEEFDA 234
Cdd:TIGR02169  690 LSSLQSELRRIENRLDELSQELSD---ASRKI-GEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQeieNVKSELKELEA 765

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   235 SLEEKDQYISVLQTQVSLLKQRLRNGPMNV------DVLKPLPQLEPQAEVFTKEENPESDGEPVVEDgtSVKTLETLQQ 308
Cdd:TIGR02169  766 RIEELEEDLHKLEEALNDLEARLSHSRIPEiqaelsKLEEEVSRIEARLREIEQKLNRLTLEKEYLEK--EIQELQEQRI 843

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   309 RVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGmvi 388
Cdd:TIGR02169  844 DLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS--- 920

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   389 aetkrQMHETLEMKEEEIAQLRSRIKQMTTQGEE------LREQKEKSERA----------AFEELEKALSTAQKTEEAR 452
Cdd:TIGR02169  921 -----ELKAKLEALEEELSEIEDPKGEDEEIPEEelsledVQAELQRVEEEiralepvnmlAIQEYEEVLKRLDELKEKR 995

                          330       340
                   ....*....|....*....|..
gi 530372328   453 RKLKAEMDEQIKTIEKTSEEER 474
Cdd:TIGR02169  996 AKLEEERKAILERIEEYEKKKR 1017
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 862-1718 1.85e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.44  E-value: 1.85e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   862 KQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREG 941
Cdd:pfam02463  172 KEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   942 QKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKmEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQF 1021
Cdd:pfam02463  252 EIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEE-LKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKEL 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1022 NAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQK 1101
Cdd:pfam02463  331 KKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLL 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1102 ILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVE 1181
Cdd:pfam02463  411 LELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLL 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1182 LKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSnksledKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINIS 1261
Cdd:pfam02463  491 SRQKLEERSQKESKARSGLKVLLALIKDGVGGRIIS------AHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQ 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1262 SSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTE 1341
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAK 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1342 KEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSL 1421
Cdd:pfam02463  645 ESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLA 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1422 RKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDE 1501
Cdd:pfam02463  725 DRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELR 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1502 QINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELksqtariMELEDHITQKTIEIESLNEVLKNYNQQKDIEH 1581
Cdd:pfam02463  805 ALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEE-------QKLEKLAEEELERLEEEITKEELLQELLLKEE 877

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1582 KELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAE 1661
Cdd:pfam02463  878 ELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEE 957

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530372328  1662 LKRKAEQKIAAIKK------QLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLK 1718
Cdd:pfam02463  958 EEERNKRLLLAKEElgkvnlMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLK 1020
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1153-1722 2.06e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 2.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1153 KLKAHLEKLEVDLnkSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLS 1232
Cdd:COG1196   217 ELKEELKELEAEL--LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1233 EELAiqldicckKTEALLEAKTNELINISSSKTNAILSRISHCQHRttkvkealliktctvSELEAQLRQLTEEQNTLNI 1312
Cdd:COG1196   295 AELA--------RLEQDIARLEERRRELEERLEELEEELAELEEEL---------------EELEEELEELEEELEEAEE 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1313 SFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEIS 1392
Cdd:COG1196   352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA 431

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1393 SLSKQLTDLNVQLQNSIS----LSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWK 1468
Cdd:COG1196   432 ELEEEEEEEEEALEEAAEeeaeLEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1469 KKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTAR 1548
Cdd:COG1196   512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAA 591

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1549 IMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKlqhfQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKK 1628
Cdd:COG1196   592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAA----RLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSR 667

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1629 ELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQERER 1708
Cdd:COG1196   668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747

                         570
                  ....*....|....
gi 530372328 1709 EVHILEEKLKSVES 1722
Cdd:COG1196   748 LEEEALEELPEPPD 761
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1532-1876 2.15e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.15  E-value: 2.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1532 EKKESNLEtELKSQTARIMELEDHITQKTIEIESLNEvlknyNQQKDIEHKELVQKLQHFQelGEEKDNRVKEAEEKILT 1611
Cdd:TIGR02169  170 RKKEKALE-ELEEVEENIERLDLIIDEKRQQLERLRR-----EREKAERYQALLKEKREYE--GYELLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1612 LENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAE---------QKIAAIKKQLLSQME 1682
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGeleaeiaslERSIAEKERELEDAE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1683 EKEEQYKKGTESHLSELnTKLQEREREVHILEEKLKSVESSQSETLIVPRSAknvaayTEQEEADSQGCVQKT--YEEKI 1760
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEI-EELEREIEEERKRRDKLTEEYAELKEELEDLRAE------LEEVDKEFAETRDELkdYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1761 SVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRcqyqerlIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEK 1840
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLN-------AAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKY 467

                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 530372328  1841 EGGKNNIQAKQN-LENVFDDVQKTLQEKELTCQILEQ 1876
Cdd:TIGR02169  468 EQELYDLKEEYDrVEKELSKLQRELAEAEAQARASEE 504
mukB PRK04863
chromosome partition protein MukB;
159-426 3.59e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 52.65  E-value: 3.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  159 EQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQS---QDKSL-RRIAELREELQMDQQAKKHLQ----- 229
Cdd:PRK04863  840 RQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLnllADETLaDRVEEIREQLDEAEEAKRFVQqhgna 919

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  230 ----EEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQlepQAEVFTKEENPESDGEpvvEDGTSvktlET 305
Cdd:PRK04863  920 laqlEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQ---RRAHFSYEDAAEMLAK---NSDLN----EK 989

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  306 LQQRVKRQENLLKRCKETIQSHKEQCTL-------LTSEKEALQEQLDERLQELEKI--------KDLHMAEKTKLITQL 370
Cdd:PRK04863  990 LRQRLEQAEQERTRAREQLRQAQAQLAQynqvlasLKSSYDAKRQMLQELKQELQDLgvpadsgaEERARARRDELHARL 1069

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 530372328  371 RDAKNLIEQLEQdkgmviaetkrqmheTLEMKEEEIAQLRSRIKQMTTQGEELREQ 426
Cdd:PRK04863 1070 SANRSRRNQLEK---------------QLTFCEAEMDNLTKKLRKLERDYHEMREQ 1110
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 192-1031 3.92e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 52.28  E-value: 3.92e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   192 EKKKLQGILSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLP 271
Cdd:pfam02463  174 ALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEI 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   272 QLEPQAEVFTKEENpesdgepvvedgtsvktletlqQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQE 351
Cdd:pfam02463  254 ESSKQEIEKEEEKL----------------------AQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVD 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   352 LEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSE 431
Cdd:pfam02463  312 DEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAK 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   432 RAAFEELEKALSTAQKTEEARRKLKAEMD-----EQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKL 506
Cdd:pfam02463  392 LKEEELELKSEEEKEAQLLLELARQLEDLlkeekKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   507 HEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRD---LQQE 583
Cdd:pfam02463  472 DLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAistAVIV 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   584 AETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTE 663
Cdd:pfam02463  552 EVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKD 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   664 MEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQEL 743
Cdd:pfam02463  632 TELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   744 EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLD 823
Cdd:pfam02463  712 LKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEE 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   824 VFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKV 903
Cdd:pfam02463  792 KEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQE 871

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   904 KSLTQVYESKLED-GNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVK 982
Cdd:pfam02463  872 LLLKEEELEEQKLkDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKE 951

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 530372328   983 QKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQA 1031
Cdd:pfam02463  952 ENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERL 1000
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 211-991 4.44e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.38  E-value: 4.44e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   211 IAELREELQMDQQAKKHLqEEFDASLEEKDQYisvlqTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEENpesdg 290
Cdd:TIGR02169  193 IDEKRQQLERLRREREKA-ERYQALLKEKREY-----EGYELLKEKEALERQKEAIERQLASLEEELEKLTEEIS----- 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   291 EPVVEDGTSVKTLETLQQRVKR----QENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKL 366
Cdd:TIGR02169  262 ELEKRLEEIEQLLEELNKKIKDlgeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEEL 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   367 ITQLRDAKNLIEQLeQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQ 446
Cdd:TIGR02169  342 EREIEEERKRRDKL-TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   447 KTEEARRKLK----------AEMDEQIKTIEKtSEEERISLQQELSRVKQEVVDvmKKSSEEQIAKLQKLHEKELARKEQ 516
Cdd:TIGR02169  421 ELADLNAAIAgieakineleEEKEDKALEIKK-QEWKLEQLAADLSKYEQELYD--LKEEYDRVEKELSKLQRELAEAEA 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   517 ELtKKLQTREREFQEQMKVALEKSQSEYLKISQ---EKEQQESLALEELELQKKAILTESE-------NKLRDLQQEAET 586
Cdd:TIGR02169  498 QA-RASEERVRGGRAVEEVLKASIQGVHGTVAQlgsVGERYATAIEVAAGNRLNNVVVEDDavakeaiELLKRRKAGRAT 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   587 Y--RTRILELESSLEKSLqenKNQSKDLAVHLEAEKNKHNKEI------TVMVEkhktELESLKHQQD------------ 646
Cdd:TIGR02169  577 FlpLNKMRDERRDLSILS---EDGVIGFAVDLVEFDPKYEPAFkyvfgdTLVVE----DIEAARRLMGkyrmvtlegelf 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   647 ---------ALWTEKLQVLKQQYQTEMEKLREkceqEKETLLKDKEIIFQ--AHIEEMNEKTLEKLDVKQTELESLSSEL 715
Cdd:TIGR02169  650 eksgamtggSRAPRGGILFSRSEPAELQRLRE----RLEGLKRELSSLQSelRRIENRLDELSQELSDASRKIGEIEKEI 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   716 SEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKnhhqqQVDSIIKEHEVSIQRTEKALKD--------QINQLELLL 787
Cdd:TIGR02169  726 EQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELK-----ELEARIEELEEDLHKLEEALNDlearlshsRIPEIQAEL 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   788 KERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEV 867
Cdd:TIGR02169  801 SKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDL 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   868 EAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVK--SLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQkKE 945
Cdd:TIGR02169  881 ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKrlSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQ-AE 959

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 530372328   946 IEILTQKLSAKEDSIHILNEEYET---KFKNQEKKMEKVKQKAKEMQET 991
Cdd:TIGR02169  960 LQRVEEEIRALEPVNMLAIQEYEEvlkRLDELKEKRAKLEEERKAILER 1008
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 761-1227 8.85e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.17  E-value: 8.85e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   761 IIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYE 840
Cdd:TIGR04523   79 ILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLN 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   841 EQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDA---------HKIQVQDLMQ----QLEKQNSEMEQKVKSLT 907
Cdd:TIGR04523  159 NKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKlelllsnlkKKIQKNKSLEsqisELKKQNNQLKDNIEKKQ 238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   908 QVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKkEIEILTQKLSAKEDSIHILNEEYE---------------TKFK 972
Cdd:TIGR04523  239 QEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQK-ELEQNNKKIKELEKQLNQLKSEISdlnnqkeqdwnkelkSELK 317

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   973 NQEKKMEKVKQKAKEMQETLKKkLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISdavsrletnQKEQIE 1052
Cdd:TIGR04523  318 NQEKKLEEIQNQISQNNKIISQ-LNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQS---------YKQEIK 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1053 SLtEVHRRELNDVISIwEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNE 1132
Cdd:TIGR04523  388 NL-ESQINDLESKIQN-QEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRES 465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1133 LQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKS 1212
Cdd:TIGR04523  466 LETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLED 545

                          490
                   ....*....|....*
gi 530372328  1213 SHEKSNKSLEDKSLE 1227
Cdd:TIGR04523  546 ELNKDDFELKKENLE 560
PTZ00121 PTZ00121
MAEBL; Provisional
 738-1249 9.01e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.30  E-value: 9.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  738 KMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQ 817
Cdd:PTZ00121 1230 KKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKK 1309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  818 ASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKdvctELDAHKIQVQDLMQQLEKQNS 897
Cdd:PTZ00121 1310 KAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE----KAEAAEKKKEEAKKKADAAKK 1385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  898 EMEQKVKSlTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKK 977
Cdd:PTZ00121 1386 KAEEKKKA-DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  978 MEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQK-EQIESLTE 1056
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKaDEAKKAEE 1544

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1057 VHRRElndviSIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQ 1136
Cdd:PTZ00121 1545 KKKAD-----ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK 1619

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1137 LK----QKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQlveLKMLAEEDKRKVSELTSKLKTTDEEFQSLKS 1212
Cdd:PTZ00121 1620 IKaeelKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAE---EAKKAEEDKKKAEEAKKAEEDEKKAAEALKK 1696

                         490       500       510
                  ....*....|....*....|....*....|....*....
gi 530372328 1213 SHEKSNKS--LEDKSLEFKKLSEELAIQLDICCKKTEAL 1249
Cdd:PTZ00121 1697 EAEEAKKAeeLKKKEAEEKKKAEELKKAEEENKIKAEEA 1735
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 890-1722 1.07e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.13  E-value: 1.07e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   890 QQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYET 969
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   970 KfkNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKE 1049
Cdd:pfam02463  249 E--QEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1050 QIESLTEVHRRELndvISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTT 1129
Cdd:pfam02463  327 EKELKKEKEEIEE---LEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1130 LNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQS 1209
Cdd:pfam02463  404 EKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQ 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1210 LKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIK 1289
Cdd:pfam02463  484 EQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEER 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1290 TCTVSELEAQLRQLTEEQnTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKE 1369
Cdd:pfam02463  564 QKLVRALTELPLGARKLR-LLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAK 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1370 LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKE 1449
Cdd:pfam02463  643 AKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEEL 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1450 KISALEQVDDWSNKFSEWKKKAQSRFTQhqntvKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKS 1529
Cdd:pfam02463  723 LADRVQEAQDKINEELKLLKQKIDEEEE-----EEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLK 797

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1530 KMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKI 1609
Cdd:pfam02463  798 AQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEE 877

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1610 LTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQ-----KIAAIKKQLLSQMEEK 1684
Cdd:pfam02463  878 ELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEpeellLEEADEKEKEENNKEE 957

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 530372328  1685 EEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVES 1722
Cdd:pfam02463  958 EEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDEL 995
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1481-1709 1.17e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 50.70  E-value: 1.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1481 TVKELQ----IQLELKSKEayEKDEQINLLKEELDQQNKRFDCLKGEME----DDKSKMEKKESNLETELKSQTARIMEL 1552
Cdd:PRK05771   21 VLEALHelgvVHIEDLKEE--LSNERLRKLRSLLTKLSEALDKLRSYLPklnpLREEKKKVSVKSLEELIKDVEEELEKI 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1553 EDHITQKTIEIESLNEVLKNYNQQKDIehkelVQKLQHF----QELGEEKD-----NRVKEAEEKILTLENQVYsmKAEL 1623
Cdd:PRK05771   99 EKEIKELEEEISELENEIKELEQEIER-----LEPWGNFdldlSLLLGFKYvsvfvGTVPEDKLEELKLESDVE--NVEY 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1624 ETKKKELEHVNLSVKSK-----EEELKALE-DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLS 1697
Cdd:PRK05771  172 ISTDKGYVYVVVVVLKElsdevEEELKKLGfERLELEEEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLA 251

                         250
                  ....*....|..
gi 530372328 1698 ELNTKLQERERE 1709
Cdd:PRK05771  252 LYEYLEIELERA 263
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2188-2227 1.37e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 43.88  E-value: 1.37e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 530372328  2188 TEFEYLRKVLFEYMMGRET---KTMAKVITTVLKFPDDQTQKI 2227
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1424-2156 1.60e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.45  E-value: 1.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1424 QYDEEK---CELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWK----KKAQSRFTQHQNTVKELQIQLELKSKEA 1496
Cdd:TIGR02169  167 EFDRKKekaLEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQallkEKREYEGYELLKEKEALERQKEAIERQL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1497 YEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESN----LETELKSQTARIMELEDHITQKTIEIESLNEVLKN 1572
Cdd:TIGR02169  247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEeqlrVKEKIGELEAEIASLERSIAEKERELEDAEERLAK 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1573 YNQQ---KDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLS---VKSKEEELKA 1646
Cdd:TIGR02169  327 LEAEidkLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKlekLKREINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1647 LEDRLESES---AAKLAELKRKAEQKIAAIKkQLLSQMEEKEEQYKKGT-------------ESHLSELNTKLQEREREV 1710
Cdd:TIGR02169  407 ELDRLQEELqrlSEELADLNAAIAGIEAKIN-ELEEEKEDKALEIKKQEwkleqlaadlskyEQELYDLKEEYDRVEKEL 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1711 HILEEKLKSVESSQSetLIVPRSAKNVAAyTEQEEADSQGcVQKTYEEKISVLQRNLTEKE----KLLQRVGQEKEETVS 1786
Cdd:TIGR02169  486 SKLQRELAEAEAQAR--ASEERVRGGRAV-EEVLKASIQG-VHGTVAQLGSVGERYATAIEvaagNRLNNVVVEDDAVAK 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1787 SHFEMRCQYQ-ERLIKLEHAEAKQHEDQSMIGHLQE------ELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDD 1859
Cdd:TIGR02169  562 EAIELLKRRKaGRATFLPLNKMRDERRDLSILSEDGvigfavDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYRM 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1860 VQktlqekeLTCQILEQK--IKELDSCLVRQKEVHRVEMEELTSKYEKLQALQqmdgrnkptelleenteekskshlvqp 1937
Cdd:TIGR02169  642 VT-------LEGELFEKSgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLK--------------------------- 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1938 KLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILK------KEYDQEREE----------KI 2001
Cdd:TIGR02169  688 RELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEeleedlSSLEQEIENvkselkeleaRI 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  2002 KQEQEDL---ELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQE------ETNQLLKKIAEKDD 2072
Cdd:TIGR02169  768 EELEEDLhklEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEkeylekEIQELQEQRIDLKE 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  2073 DLKRTAKRYEEI------LDAREEEMTAKVRDLQTQLEELQKKYQ----QKLEQEENPGNDNTQLAQKTTLISDSKLKEQ 2142
Cdd:TIGR02169  848 QIKSIEKEIENLngkkeeLEEELEELEAALRDLESRLGDLKKERDeleaQLRELERKIEELEAQIEKKRKRLSELKAKLE 927

                          810
                   ....*....|....
gi 530372328  2143 EFREQIHNLEDRLK 2156
Cdd:TIGR02169  928 ALEEELSEIEDPKG 941
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 321-1237 1.61e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 50.43  E-value: 1.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   321 KETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLhmaEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLE 400
Cdd:TIGR00606  151 NNVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKAL---ETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQIT 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   401 MKEEEIAQLRSRIKQMTTQGEELREQKEKSE--RAAFEELEKALSTAQKTEEARRKLKAEM-----------DEQIKTIE 467
Cdd:TIGR00606  228 SKEAQLESSREIVKSYENELDPLKNRLKEIEhnLSKIMKLDNEIKALKSRKKQMEKDNSELelkmekvfqgtDEQLNDLY 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   468 -------KTSEEERISLQQELSRVKQEVVDVMKKSSEEQIA------KLQKLHEKELARKEQELTKKLQTREREFQEQMK 534
Cdd:TIGR00606  308 hnhqrtvREKERELVDCQRELEKLNKERRLLNQEKTELLVEqgrlqlQADRHQEHIRARDSLIQSLATRLELDGFERGPF 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   535 VALEKSQSEYLKIS-QEKEQQESLALEELELQKKAILTESENKLRDlqqeAETYRTRILELESSLeksLQENKNQSKDLA 613
Cdd:TIGR00606  388 SERQIKNFHTLVIErQEDEAKTAAQLCADLQSKERLKQEQADEIRD----EKKGLGRTIELKKEI---LEKKQEELKFVI 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   614 VHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEM 693
Cdd:TIGR00606  461 KELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEML 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   694 NEKTLEKLD----------VKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELeAKMDEQKNHHQQQVDSiIK 763
Cdd:TIGR00606  541 TKDKMDKDEqirkiksrhsDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKEL-ASLEQNKNHINNELES-KE 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   764 EHEVSIQR------TEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTK 837
Cdd:TIGR00606  619 EQLSSYEDklfdvcGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFIS 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   838 AYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMeQKVKSLTQVYESKLEDG 917
Cdd:TIGR00606  699 DLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDI-QRLKNDIEEQETLLGTI 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   918 NKEQEQTKQILVEKEnmILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEK--KMEKVKQKAKEMQetlkkK 995
Cdd:TIGR00606  778 MPEEESAKVCLTDVT--IMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKqhELDTVVSKIELNR-----K 850

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   996 LLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANsagisdavSRLETNQKEQIESLTEV-HRRELNDVISIWEKKLN 1074
Cdd:TIGR00606  851 LIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFE--------EQLVELSTEVQSLIREIkDAKEQDSPLETFLEKDQ 922

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1075 QQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQ-DTTLNELQEQLKQKSAHVNSLAQDetk 1153
Cdd:TIGR00606  923 QEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQkETELNTVNAQLEECEKHQEKINED--- 999

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1154 lkahLEKLEVDLNKSLKENTFLQEQLVELKMlaeedKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSE 1233
Cdd:TIGR00606 1000 ----MRLMRQDIDTQKIQERWLQDNLTLRKR-----ENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNH 1070


                   ....
gi 530372328  1234 ELAI 1237
Cdd:TIGR00606 1071 VLAL 1074
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 160-701 1.79e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.32  E-value: 1.79e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  160 QLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQgilsQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEK 239
Cdd:COG1196   292 ELLAELARLEQDIARLEERRRELEERLEELEEELAELE----EELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  240 DQYISVLQTQVSLLKQRLRngpmnvDVLKPLPQLEPQAEVFTKEENPESDGEpvVEDGTSVKTLETLQQRVKRQENLLKR 319
Cdd:COG1196   368 LEAEAELAEAEEELEELAE------ELLEALRAAAELAAQLEELEEAEEALL--ERLERLEEELEELEEALAELEEEEEE 439

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  320 CKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETL 399
Cdd:COG1196   440 EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGL 519

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  400 EMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQ 479
Cdd:COG1196   520 RGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGA 599

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  480 ELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALE-KSQSEYLKISQEKEQQESLA 558
Cdd:COG1196   600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAgGSLTGGSRRELLAALLEAEA 679

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  559 LEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTEL 638
Cdd:COG1196   680 ELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP 759

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530372328  639 ESLKHQQdalwtEKLQVLKQQYQT----------EMEKLREKCE---QEKETLLKDKEIIFQAhIEEMNEKTLEKL 701
Cdd:COG1196   760 PDLEELE-----RELERLEREIEAlgpvnllaieEYEELEERYDflsEQREDLEEARETLEEA-IEEIDRETRERF 829
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
317-544 1.96e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.91  E-value: 1.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  317 LKRCKETIQSHKEQCTLLTSEKEALQE--QLDERLQELEKIKdlHMAEKTKLITQLRDAKNLIEQLEQDkgmviaetkrq 394
Cdd:COG4913   237 LERAHEALEDAREQIELLEPIRELAERyaAARERLAELEYLR--AALRLWFAQRRLELLEAELEELRAE----------- 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  395 mhetLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEER 474
Cdd:COG4913   304 ----LARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASA 379

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  475 islqQELSRVKQEVVDVMKKSSEEQIAKLQKLHekELARKEQELTKKLQTREREFQeqmkvALEKSQSEY 544
Cdd:COG4913   380 ----EEFAALRAEAAALLEALEEELEALEEALA--EAEAALRDLRRELRELEAEIA-----SLERRKSNI 438
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 578-1139 2.34e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.94  E-value: 2.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  578 RDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLK 657
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  658 QQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTD 737
Cdd:COG1196   296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  738 KMKQELEAKMDEQKNHHQQQVDsiIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQ 817
Cdd:COG1196   376 EAEEELEELAEELLEALRAAAE--LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  818 ASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVcteLDAHKIQVQDLMQQLEKQNS 897
Cdd:COG1196   454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV---KAALLLAGLRGLAGAVAVLI 530

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  898 EMEQKVKSLTQVYESKLEDGNkeQEQTKQILVEKENMILQMREGQKKEIEILTQK-LSAKEDSIHILNEEYETKFKNQEK 976
Cdd:COG1196   531 GVEAAYEAALEAALAAALQNI--VVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRaRAALAAALARGAIGAAVDLVASDL 608

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  977 KMEKVKQKAKEMQ---ETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKmLEMAQANSAGISDAVSRLETNQKEQIES 1053
Cdd:COG1196   609 READARYYVLGDTllgRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAG-GSLTGGSRRELLAALLEAEAELEELAER 687

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1054 LTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFgcEKEEMNKEITWLKEEGVKQDTTLNEL 1133
Cdd:COG1196   688 LAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLE--ELLEEEELLEEEALEELPEPPDLEEL 765


                  ....*.
gi 530372328 1134 QEQLKQ 1139
Cdd:COG1196   766 ERELER 771
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1483-2152 2.53e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.58  E-value: 2.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1483 KELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIE 1562
Cdd:pfam02463  207 KKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEE 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1563 IESLNEVLKNYNQQKDIehkelvqKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEE 1642
Cdd:pfam02463  287 ELKLLAKEEEELKSELL-------KLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1643 ELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQykkgteshlSELNTKLQEREREVHILEEKLKSVES 1722
Cdd:pfam02463  360 ELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEE---------KEAQLLLELARQLEDLLKEEKKEELE 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1723 SQSETLIVPRSAKNVAAyTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKL 1802
Cdd:pfam02463  431 ILEEEEESIELKQGKLT-EEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGL 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1803 EHAEAkqhedQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELD 1882
Cdd:pfam02463  510 KVLLA-----LIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLI 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1883 SCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQ 1962
Cdd:pfam02463  585 PKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEV 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1963 KLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETI 2042
Cdd:pfam02463  665 KASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQK 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  2043 NKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGN 2122
Cdd:pfam02463  745 IDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLI 824

                          650       660       670
                   ....*....|....*....|....*....|
gi 530372328  2123 DNTQLAQKTTLISDSKLKEQEFREQIHNLE 2152
Cdd:pfam02463  825 EQEEKIKEEELEELALELKEEQKLEKLAEE 854
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1603-1911 2.59e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.68  E-value: 2.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1603 KEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLE--SESAAKLAELKRKAEQKIAAIKKQLLSQ 1680
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGeiEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1681 MEEKEEQykkgtESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIvprsaknvaaYTEQEEADSQGCVQKTYEEKI 1760
Cdd:TIGR02169  750 EQEIENV-----KSELKELEARIEELEEDLHKLEEALNDLEARLSHSRI----------PEIQAELSKLEEEVSRIEARL 814

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1761 SVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEK 1840
Cdd:TIGR02169  815 REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDEL 894

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530372328  1841 EGGKNNIQAKQN-LENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMeELTSKYEKLQALQQ 1911
Cdd:TIGR02169  895 EAQLRELERKIEeLEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEEL-SLEDVQAELQRVEE 965
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 458-1168 3.01e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 49.35  E-value: 3.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   458 EMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIaklqklhekelarkEQELTKKLQTREREFQEQMKVAL 537
Cdd:pfam15921   82 EYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQM--------------ERDAMADIRRRESQSQEDLRNQL 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   538 EKSQSEYLKISQEKEQQESLALEELELQKKAILTEsENKLRDLqqeaetyRTRILELESSLEKSLQENKNQSkdlAVHLE 617
Cdd:pfam15921  148 QNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSH-EGVLQEI-------RSILVDFEEASGKKIYEHDSMS---TMHFR 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   618 AeknkHNKEITVMVEKHKTELESLKHQQDALwTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIifqaHIEEMNEKT 697
Cdd:pfam15921  217 S----LGSAISKILRELDTEISYLKGRIFPV-EDQLEALKSESQNKIELLLQQHQDRIEQLISEHEV----EITGLTEKA 287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   698 LEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQEL-EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEK-- 774
Cdd:pfam15921  288 SSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELrEAKRMYEDKIEELEKQLVLANSELTEARTERdq 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   775 ------ALKDQINQLELLLKERDKHLKEHQAH--------------VENLEADIKRSEGELQQASAKLDVFQSYQSATHE 834
Cdd:pfam15921  368 fsqesgNLDDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitIDHLRRELDDRNMEVQRLEALLKAMKSECQGQME 447

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   835 QTKAY----EEQLAQLQQKLLDLETERILLTKQVAEVEAQKkdvcTELDAHKIQVQDLMQQLEKQNSEME------QKVK 904
Cdd:pfam15921  448 RQMAAiqgkNESLEKVSSLTAQLESTKEMLRKVVEELTAKK----MTLESSERTVSDLTASLQEKERAIEatnaeiTKLR 523

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   905 SLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREgQKKEIEILTQKLsakEDSIHILNEEYETKFKNQEKKMEKVK-- 982
Cdd:pfam15921  524 SRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAE-KDKVIEILRQQI---ENMTQLVGQHGRTAGAMQVEKAQLEKei 599

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   983 -------QKAKEMQETLKKKLLDQEAKLKK-ELENTALELSQKE--------KQFNAKMLEMAQANSAGISDAVSRLET- 1045
Cdd:pfam15921  600 ndrrlelQEFKILKDKKDAKIRELEARVSDlELEKVKLVNAGSErlravkdiKQERDQLLNEVKTSRNELNSLSEDYEVl 679

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1046 -----NQKEQIESLTEVHRRELNDVISIWEKKLNQ-QAEELQEIHEI--------QLQEKEQEVAELKQKILLFGCEKEE 1111
Cdd:pfam15921  680 krnfrNKSEEMETTTNKLKMQLKSAQSELEQTRNTlKSMEGSDGHAMkvamgmqkQITAKRGQIDALQSKIQFLEEAMTN 759

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 530372328  1112 MNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKS 1168
Cdd:pfam15921  760 ANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKA 816
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1600-2119 3.29e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.29  E-value: 3.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1600 NRVKEAEEKILT----LENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLEsesaaklaELKRKAEqKIAAIKK 1675
Cdd:PRK03918  175 KRRIERLEKFIKrtenIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVK--------ELEELKE-EIEELEK 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1676 QLlsqmeEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGcvQKT 1755
Cdd:PRK03918  246 EL-----ESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKR--LSR 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1756 YEEKISVLQRNLTEKEKLLQRVGQEKEETVsshfemrcQYQERLIKLEhaeaKQHEDQSMIGHLQEELEEKNKKYSLIVA 1835
Cdd:PRK03918  319 LEEEINGIEERIKELEEKEERLEELKKKLK--------ELEKRLEELE----ERHELYEEAKAKKEELERLKKRLTGLTP 386

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1836 QHVEKEGgKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDS----CLVRQKEVHRVEMEELTSKY-------- 1903
Cdd:PRK03918  387 EKLEKEL-EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkCPVCGRELTEEHRKELLEEYtaelkrie 465

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1904 EKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEF----KLAGAEREKQKLGKEIVRLQKDLRMLR 1979
Cdd:PRK03918  466 KELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKynleELEKKAEEYEKLKEKLIKLKGEIKSLK 545

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1980 KEhQQELEILKKEYDQEREEKIKQEQEDLELKHNstLKQLMREFNTQLAQKEQELEMTIKETIN-----KAQEVEAELLE 2054
Cdd:PRK03918  546 KE-LEKLEELKKKLAELEKKLDELEEELAELLKE--LEELGFESVEELEERLKELEPFYNEYLElkdaeKELEREEKELK 622

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530372328 2055 SHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEEN 2119
Cdd:PRK03918  623 KLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEK 687
PRK12704 PRK12704
phosphodiesterase; Provisional
 1571-1684 3.41e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 49.01  E-value: 3.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1571 KNYNQQKDIEHKELVQKL--QHFQELgEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALE 1648
Cdd:PRK12704   52 EAIKKEALLEAKEEIHKLrnEFEKEL-RERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKE 130

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 530372328 1649 DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEK 1684
Cdd:PRK12704  131 EELEELIEEQLQELERISGLTAEEAKEILLEKVEEE 166
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 209-520 3.69e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 49.28  E-value: 3.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   209 RRIAELREELQMDQQAKKHLQEEFDA---SLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEEN 285
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAElrkELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   286 PESDGEPVVEDgtsvKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELekikdlhmAEKTK 365
Cdd:TIGR02168  757 TELEAEIEELE----ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEA--------ANLRE 824

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   366 LITQLRDAKNLIEQLEQDkgmvIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERA---AFEELEKAL 442
Cdd:TIGR02168  825 RLESLERRIAATERRLED----LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAlalLRSELEELS 900

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530372328   443 STAQKTEEARRKLKAEMDEQiKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEqIAKLQKLHEKELARKEQELTK 520
Cdd:TIGR02168  901 EELRELESKRSELRRELEEL-REKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEE-AEALENKIEDDEEEARRRLKR 976
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1471-1694 3.73e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 48.29  E-value: 3.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1471 AQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLET---ELKSQTA 1547
Cdd:COG3883    14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEErreELGERAR 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1548 RIMELEDHITQKTI--EIESLNEVLKNYNQQKDIE--HKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAEL 1623
Cdd:COG3883    94 ALYRSGGSVSYLDVllGSESFSDFLDRLSALSKIAdaDADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530372328 1624 ETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTES 1694
Cdd:COG3883   174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 244
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1119-1744 4.39e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 48.86  E-value: 4.39e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1119 LKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTS 1198
Cdd:TIGR04523   24 YKNIANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1199 KLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEA-----KTNELINISSSKTNAILSRIS 1273
Cdd:TIGR04523  104 DLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLnnkynDLKKQKEELENELNLLEKEKL 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1274 HCQHRTTKVKEALLIKTCTVSELEAqlrqLTEEQNTLNIsfqqathQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQ 1353
Cdd:TIGR04523  184 NIQKNIDKIKNKLLKLELLLSNLKK----KIQKNKSLES-------QISELKKQNNQLKDNIEKKQQEINEKTTEISNTQ 252

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1354 QAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSIS------LSEKEAAISSLRKQYDE 1427
Cdd:TIGR04523  253 TQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNkelkseLKNQEKKLEEIQNQISQ 332

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1428 EK---CELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQN---TVKELQIQLELKSKEAYEKDE 1501
Cdd:TIGR04523  333 NNkiiSQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNlesQINDLESKIQNQEKLNQQKDE 412

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1502 QINLLKEELDQQNKRFDCLKGEMEDDKSKMekkeSNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEH 1581
Cdd:TIGR04523  413 QIKKLQQEKELLEKEIERLKETIIKNNSEI----KDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQ 488

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1582 KELVQKLQHFQELGEEKdnrvKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAE 1661
Cdd:TIGR04523  489 KELKSKEKELKKLNEEK----KELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEID 564

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1662 LKRKAEQKIAAIKKQLLSQMEEKEEQYKKgTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYT 1741
Cdd:TIGR04523  565 EKNKEIEELKQTQKSLKKKQEEKQELIDQ-KEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKL 643


                   ...
gi 530372328  1742 EQE 1744
Cdd:TIGR04523  644 KQE 646
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1292-1827 5.36e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.50  E-value: 5.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1292 TVSELEAQLRQLTEEQNTLNISFQQATHQL----------EEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKES 1361
Cdd:PRK02224  207 RLNGLESELAELDEEIERYEEQREQARETRdeadevleehEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRE 286

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1362 CITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQL-QNSISLSEKEAAISSLRKQYDEekceLLDQVQDLS 1440
Cdd:PRK02224  287 RLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLeECRVAAQAHNEEAESLREDADD----LEERAEELR 362

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1441 FKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKE-ELDQQNKRFDC 1519
Cdd:PRK02224  363 EEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAElEATLRTARERV 442

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1520 LKGEMEDDKSK-----MEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHK--ELVQKLQHFQ 1592
Cdd:PRK02224  443 EEAEALLEAGKcpecgQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRieRLEERREDLE 522

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1593 ELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLEsESAAKLAELKRKAEqkiaa 1672
Cdd:PRK02224  523 ELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLA-ELKERIESLERIRT----- 596

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1673 ikkqLLSQMEEKEEQYKKGTE--SHLSELNTKLQEREREvhiLEEKLKSVESSQSETLIvprsaknvaayteqEEADSQG 1750
Cdd:PRK02224  597 ----LLAAIADAEDEIERLREkrEALAELNDERRERLAE---KRERKRELEAEFDEARI--------------EEAREDK 655

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1751 CVQKTYEEKISVLQRNLTEKE-KLLQRVGQEKEE--TVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKN 1827
Cdd:PRK02224  656 ERAEEYLEQVEEKLDELREERdDLQAEIGAVENEleELEELRERREALENRVEALEALYDEAEELESMYGDLRAELRQRN 735
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1358-2092 5.97e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.43  E-value: 5.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1358 EKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQ 1437
Cdd:pfam02463  206 AKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1438 DLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLE--LKSKEAYEKDEQINLLKEELDQQNK 1515
Cdd:pfam02463  286 EELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEelEKELKELEIKREAEEEEEEELEKLQ 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1516 RFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLknyNQQKDIEHKELVQKLQHFQELG 1595
Cdd:pfam02463  366 EKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDL---LKEEKKEELEILEEEEESIELK 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1596 EEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEhvnlSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKK 1675
Cdd:pfam02463  443 QGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ----LVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKD 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1676 QLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADsqgcvqkt 1755
Cdd:pfam02463  519 GVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLP-------- 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1756 yEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVA 1835
Cdd:pfam02463  591 -LKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLS 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1836 QHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGR 1915
Cdd:pfam02463  670 ELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEE 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1916 NKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQ 1995
Cdd:pfam02463  750 EEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEK 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1996 EREEKIKQEQEDLEL-----KHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEK 2070
Cdd:pfam02463  830 IKEEELEELALELKEeqkleKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKL 909

                          730       740
                   ....*....|....*....|..
gi 530372328  2071 DDDLKRTAKRYEEILDAREEEM 2092
Cdd:pfam02463  910 NLLEEKENEIEERIKEEAEILL 931
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 478-806 7.68e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 47.81  E-value: 7.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   478 QQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQeltkkLQTREREFQEQMKVALEKSQsEYLKISQEKEQQESL 557
Cdd:pfam17380  290 QEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAE-----MDRQAAIYAEQERMAMERER-ELERIRQEERKRELE 363

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   558 ALEElelQKKAILTESENKLRDLQQEAETYRTRI-LELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEitvmvEKHKT 636
Cdd:pfam17380  364 RIRQ---EEIAMEISRMRELERLQMERQQKNERVrQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQE-----EARQR 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   637 ELESLKHQQdALWTEKLQVLKQQYQTEMEKLRE-KCEQEKETLLKDKEIIFQAHIEEMNEKTLEKldvkqtELESLSSEL 715
Cdd:pfam17380  436 EVRRLEEER-AREMERVRLEEQERQQQVERLRQqEEERKRKKLELEKEKRDRKRAEEQRRKILEK------ELEERKQAM 508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   716 SEVLKARHKLEEElsvLKDQTDKMKQELEAKMDEQKNHHQQQVdsiikEHEVSIQRTEKALKDQINQLELLLKERD--KH 793
Cdd:pfam17380  509 IEEERKRKLLEKE---MEERQKAIYEEERRREAEEERRKQQEM-----EERRRIQEQMRKATEERSRLEAMEREREmmRQ 580

                          330
                   ....*....|...
gi 530372328   794 LKEHQAHVENLEA 806
Cdd:pfam17380  581 IVESEKARAEYEA 593
PTZ00121 PTZ00121
MAEBL; Provisional
 301-626 8.50e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.21  E-value: 8.50e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  301 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKnlIEQL 380
Cdd:PTZ00121 1535 KADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMK--AEEA 1612

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  381 EQdkgmviAETKRQMHETLEMKEEE---IAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARrklKA 457
Cdd:PTZ00121 1613 KK------AEEAKIKAEELKKAEEEkkkVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAK---KA 1683

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  458 EMDEQIKTIEKTSEEERISLQQELSRVKQEVV---DVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMK 534
Cdd:PTZ00121 1684 EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKkkaEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLK 1763

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  535 VALEKSQSEYLK-----ISQEKEQQESLALEELELQKKAILTESENkLRDLQQEAETYRTRILELESSLEKSLQENKNQS 609
Cdd:PTZ00121 1764 KEEEKKAEEIRKekeavIEEELDEEDEKRRMEVDKKIKDIFDNFAN-IIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQ 1842

                         330
                  ....*....|....*..
gi 530372328  610 KDLAVHLEAEKNKHNKE 626
Cdd:PTZ00121 1843 LEEADAFEKHKFNKNNE 1859
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1267-1829 8.77e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.91  E-value: 8.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1267 AILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQlteEQNTLNISFQQATHQLEEKENQ--------IKSMKADIE-- 1336
Cdd:pfam12128  273 LIASRQEERQETSAELNQLLRTLDDQWKEKRDELNG---ELSAADAAVAKDRSELEALEDQhgafldadIETAAADQEql 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1337 -SLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKE 1415
Cdd:pfam12128  350 pSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLE 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1416 AAISSLRkqydEEKCELLDQVQDLSFKVD--TLSKEKISALEQVDDWSNKfsewkkkAQSRFTQHQNTVKELQIQLELKS 1493
Cdd:pfam12128  430 AGKLEFN----EEEYRLKSRLGELKLRLNqaTATPELLLQLENFDERIER-------AREEQEAANAEVERLQSELRQAR 498

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1494 KEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELED-HITQKTIEI--ESLNEVL 1570
Cdd:pfam12128  499 KRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELlHRTDLDPEVwdGSVGGEL 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1571 KNYNQQKDIEHKELVQKLQHFQELGEEKD---NRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKAL 1647
Cdd:pfam12128  579 NLYGVKLDLKRIDVPEWAASEEELRERLDkaeEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRL 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1648 EDRLESESAAK---LAELKRKAEQKIAAIKKQlLSQMEEKEEQYKKGTESHLSELNTKLQEREREVhilEEKLKSVESSQ 1724
Cdd:pfam12128  659 FDEKQSEKDKKnkaLAERKDSANERLNSLEAQ-LKQLDKKHQAWLEEQKEQKREARTEKQAYWQVV---EGALDAQLALL 734

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1725 SETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQY----QERLI 1800
Cdd:pfam12128  735 KAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWlqrrPRLAT 814

                          570       580
                   ....*....|....*....|....*....
gi 530372328  1801 KLEHAEAKQHEDQSMIGHLQEELEEKNKK 1829
Cdd:pfam12128  815 QLSNIERAISELQQQLARLIADTKLRRAK 843
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
343-906 9.78e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 9.78e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  343 EQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHEtLEMKEEEIAQLRSRIKQMTTQGEE 422
Cdd:PRK03918  161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSE-LPELREELEKLEKEVKELEELKEE 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  423 LREQKEK--SERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIE--KTSEEERISLQQELSRVKQEVVDVMKKSS-- 496
Cdd:PRK03918  240 IEELEKEleSLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKelKEKAEEYIKLSEFYEEYLDELREIEKRLSrl 319

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  497 EEQIAKLQKLHEK--ELARKEQELTKKLQTREREFQEqmkvaLEKSQSEYLKISQEKEQqeslaleeLELQKKAILTESE 574
Cdd:PRK03918  320 EEEINGIEERIKEleEKEERLEELKKKLKELEKRLEE-----LEERHELYEEAKAKKEE--------LERLKKRLTGLTP 386

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  575 NKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITV---MVEKHKTELESLKHQQDALWTE 651
Cdd:PRK03918  387 EKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCgreLTEEHRKELLEEYTAELKRIEK 466

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  652 KLQVLKQQyqteMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKAR-HKLEEELS 730
Cdd:PRK03918  467 ELKEIEEK----ERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKlIKLKGEIK 542

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  731 VLKDQTDKmKQELE---AKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKhLKEHQAHVENLEAD 807
Cdd:PRK03918  543 SLKKELEK-LEELKkklAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLE-LKDAEKELEREEKE 620

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  808 IKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERilLTKQVAEVEAQKKdvctELDAHKIQVQD 887
Cdd:PRK03918  621 LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLE--LSRELAGLRAELE----ELEKRREEIKK 694

                         570
                  ....*....|....*....
gi 530372328  888 LMQQLEKQNSEMEQKVKSL 906
Cdd:PRK03918  695 TLEKLKEELEEREKAKKEL 713
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 304-978 1.21e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 47.66  E-value: 1.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   304 ETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLdeRLQELEKIKDLHMAEKTKLITQLRDAKNLIEQ---- 379
Cdd:TIGR00618  215 DTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQL--KKQQLLKQLRARIEELRAQEAVLEETQERINRarka 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   380 ----LEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKL 455
Cdd:TIGR00618  293 aplaAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISC 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   456 KAEMDEQ----IKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHekelARKEQELTKKLQTREREF-- 529
Cdd:TIGR00618  373 QQHTLTQhihtLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAH----AKKQQELQQRYAELCAAAit 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   530 -QEQMKVALEKSQSEYLKISQEKEQQESLALEELElQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQ 608
Cdd:TIGR00618  449 cTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHL-QETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLT 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   609 SKDLAVHLEaeknkhnkeitvmVEKHKTELESLKHQQDALwTEKLQVLKQQYQTEMEKLREKCEQEKET-----LLKDKE 683
Cdd:TIGR00618  528 RRMQRGEQT-------------YAQLETSEEDVYHQLTSE-RKQRASLKEQMQEIQQSFSILTQCDNRSkedipNLQNIT 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   684 IIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKnHHQQQVDSIIK 763
Cdd:TIGR00618  594 VRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVR-EHALSIRVLPK 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   764 EHEVSIQRTEKALKDQINQLELLLKE-RDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQ 842
Cdd:TIGR00618  673 ELLASRQLALQKMQSEKEQLTYWKEMlAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQA 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   843 LAQLQQKLLDLETERILLTKQVaEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQE 922
Cdd:TIGR00618  753 RTVLKARTEAHFNNNEEVTAAL-QTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEE 831

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 530372328   923 QTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKM 978
Cdd:TIGR00618  832 QFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQ 887
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 580-1232 1.25e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.53  E-value: 1.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   580 LQQEAETYRTRILEL-------------ESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQD 646
Cdd:pfam12128  246 LQQEFNTLESAELRLshlhfgyksdetlIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELE 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   647 ALWTEKLQVLkqqyQTEMEKLREKCEQEKEtllkdkeiiFQAHIEEMNEKtLEKLDVKQteLESLSSELSEVLKARHKLE 726
Cdd:pfam12128  326 ALEDQHGAFL----DADIETAAADQEQLPS---------WQSELENLEER-LKALTGKH--QDVTAKYNRRRSKIKEQNN 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   727 EELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKA----------LKDQINQL----ELLLKERDK 792
Cdd:pfam12128  390 RDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEeyrlksrlgeLKLRLNQAtatpELLLQLENF 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   793 -----HLKEHQ----AHVENLEADIKRSEG-------ELQQASAKLDVFQSYQSATHEQTKA---------YEEQLAQLQ 847
Cdd:pfam12128  470 derieRAREEQeaanAEVERLQSELRQARKrrdqaseALRQASRRLEERQSALDELELQLFPqagtllhflRKEAPDWEQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   848 QKLLDLETERILLTKQVAEV-EAQKKDVCT----ELDAHKIQVQDLMQqlekqnseMEQKVKSLTQVYESKLEDGNKEQE 922
Cdd:pfam12128  550 SIGKVISPELLHRTDLDPEVwDGSVGGELNlygvKLDLKRIDVPEWAA--------SEEELRERLDKAEEALQSAREKQA 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   923 QTKQILVEKENmilQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQ--ETLKKKLLDQE 1000
Cdd:pfam12128  622 AAEEQLVQANG---ELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNslEAQLKQLDKKH 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1001 AKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELN--DVISIWEKKLNQQAE 1078
Cdd:pfam12128  699 QAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLAslGVDPDVIAKLKREIR 778

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1079 ELQEIHEiQLQEKEQEVAELKQkillfgCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNS-LAQDETKLKAh 1157
Cdd:pfam12128  779 TLERKIE-RIAVRRQEVLRYFD------WYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLrRAKLEMERKA- 850

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530372328  1158 LEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSeLTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLS 1232
Cdd:pfam12128  851 SEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGS-IGERLAQLEDLKLKRDYLSESVKKYVEHFKNVIADHS 924
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1940-2156 1.33e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.36  E-value: 1.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1940 LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEhQQELEILKKEYDQEREEKIKQEQEDLELKHNST--LK 2017
Cdd:TIGR02168  269 LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRER-LANLERQLEELEAQLEELESKLDELAEELAELEekLE 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  2018 QLMREFNtQLAQKEQELEMTIKETINKAQEVEAELLE------SHQEETNQLLKKIAEKDDDLKRTAKRYE----EILDA 2087
Cdd:TIGR02168  348 ELKEELE-SLEAELEELEAELEELESRLEELEEQLETlrskvaQLELQIASLNNEIERLEARLERLEDRRErlqqEIEEL 426

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530372328  2088 REEEMTAKVRDLQTQLEELQKKYQQKLEQEENPgndNTQLAQKTTLISDSKLKEQEFREQIHNLEDRLK 2156
Cdd:TIGR02168  427 LKKLEEAELKELQAELEELEEELEELQEELERL---EEALEELREELEEAEQALDAAERELAQLQARLD 492
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1950-2169 1.49e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.36  E-value: 1.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1950 LEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEH---QQELEILKKEYDQereekIKQEQEDLELKhnstlKQLMREFNTQ 2026
Cdd:TIGR02168  244 LQEELKEAEEELEELTAELQELEEKLEELRLEVselEEEIEELQKELYA-----LANEISRLEQQ-----KQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  2027 LAQKEQELEMTIKETINKAQEVEAELLEShQEETNQLLKKIAEKDDDLKRtakryeeiLDAREEEMTAKVRDLQTQLEEL 2106
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAEL-EEKLEELKEELESLEAELEE--------LEAELEELESRLEELEEQLETL 384

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530372328  2107 QKKYQQKLEQEEnpgNDNTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNVYATTVGT 2169
Cdd:TIGR02168  385 RSKVAQLELQIA---SLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEE 444
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 389-610 1.49e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  389 AETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAfEELEKALSTAQKTEEARRKLKAEMDEQIKTIEK 468
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI-AALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  469 TSEE------ERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLheKELARKEQELTKKLQTREREFQEQmKVALEKSQS 542
Cdd:COG4942    98 ELEAqkeelaELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYL--KYLAPARREQAEELRADLAELAAL-RAELEAERA 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530372328  543 EyLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSK 610
Cdd:COG4942   175 E-LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
139-426 1.51e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 1.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  139 PSDMDSEAEDLVGNSDSLNK-EQLIQRLRRMERSLS---SYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLR-RIAE 213
Cdd:COG4913   220 EPDTFEAADALVEHFDDLERaHEALEDAREQIELLEpirELAERYAAARERLAELEYLRAALRLWFAQRRLELLEaELEE 299

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  214 LREELQMDQQAKKHLQEEFDASLEEKDQyisvlqtqvsLLKQRLRNGpmnVDVLKPLPQLEPQAEvftkeenpesdgepv 293
Cdd:COG4913   300 LRAELARLEAELERLEARLDALREELDE----------LEAQIRGNG---GDRLEQLEREIERLE--------------- 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  294 vedgtsvKTLETLQQRVKRQENLLKRCKETIQSHKEqctlltsEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDA 373
Cdd:COG4913   352 -------RELEERERRRARLEALLAALGLPLPASAE-------EFAALRAEAAALLEALEEELEALEEALAEAEAALRDL 417

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 530372328  374 KNLIEQLEQdkgmviaetkrqmhetlemkeeEIAQLRSRIKQMTTQGEELREQ 426
Cdd:COG4913   418 RRELRELEA----------------------EIASLERRKSNIPARLLALRDA 448
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
370-841 1.53e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.96  E-value: 1.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  370 LRDAKNLIEQLEQDkgmvIAETK-RQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSE---------RAAFEELE 439
Cdd:PRK02224  182 LSDQRGSLDQLKAQ----IEEKEeKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADevleeheerREELETLE 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  440 KALSTAQKTEEARRKLKAEMDEQIKTIEKTSEE-------------------ERISLQQE-LSRVKQEVVDVMkksseEQ 499
Cdd:PRK02224  258 AEIEDLRETIAETEREREELAEEVRDLRERLEEleeerddllaeaglddadaEAVEARREeLEDRDEELRDRL-----EE 332

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  500 IAKLQKLHEKElARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK-----AILTESE 574
Cdd:PRK02224  333 CRVAAQAHNEE-AESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERfgdapVDLGNAE 411

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  575 NKLRDLQQEAETYRTRILELESSLeKSLQENKNQSKDLavhLEA----------EKNKHNKEIT---VMVEKHKTELESL 641
Cdd:PRK02224  412 DFLEELREERDELREREAELEATL-RTARERVEEAEAL---LEAgkcpecgqpvEGSPHVETIEedrERVEELEAELEDL 487

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  642 KHQQDALwTEKLQVLKQQYQTE--MEKLREKCEQEKEtLLKDKEiifqAHIEEMNEKTLEKLDVKQTELESLSSELSEVL 719
Cdd:PRK02224  488 EEEVEEV-EERLERAEDLVEAEdrIERLEERREDLEE-LIAERR----ETIEEKRERAEELRERAAELEAEAEEKREAAA 561

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  720 KARHKLEEELSVLKdqtdkmkqELEAKMDEQKNHHQQ--QVDSIIKEHEVSIQRTEKaLKDQINQLELLLKERDKHLKEH 797
Cdd:PRK02224  562 EAEEEAEEAREEVA--------ELNSKLAELKERIESleRIRTLLAAIADAEDEIER-LREKREALAELNDERRERLAEK 632

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
gi 530372328  798 QAHVENLEADIkrSEGELQQASAKLDVFQSYQSATHEQTKAYEE 841
Cdd:PRK02224  633 RERKRELEAEF--DEARIEEAREDKERAEEYLEQVEEKLDELRE 674
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 635-1717 2.83e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 46.58  E-value: 2.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   635 KTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNeKTLEKLDVKQTELESLSSE 714
Cdd:TIGR01612  695 KAKLDDLKSKIDKEYDKIQNMETATVELHLSNIENKKNELLDIIVEIKKHIHGEINKDLN-KILEDFKNKEKELSNKIND 773

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   715 LSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSI----IKEHEVSIQRTE-KALKDQI-NQLELLLK 788
Cdd:TIGR01612  774 YAKEKDELNKYKSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIktisIKEDEIFKIINEmKFMKDDFlNKVDKFIN 853

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   789 ERDKHLKEHQAHVENLEADIKRSEGEL--QQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILL-TKQVA 865
Cdd:TIGR01612  854 FENNCKEKIDSEHEQFAELTNKIKAEIsdDKLNDYEKKFNDSKSLINEINKSIEEEYQNINTLKKVDEYIKICEnTKESI 933

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   866 EVEAQKKDVCTELDAHKIQVQDLMQQLEK------QNSEMEQKV---KSLTQVYESKLEDGNKEQEQTKQILVE-----K 931
Cdd:TIGR01612  934 EKFHNKQNILKEILNKNIDTIKESNLIEKsykdkfDNTLIDKINeldKAFKDASLNDYEAKNNELIKYFNDLKAnlgknK 1013

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   932 ENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEmqetlkkkLLDQEAKLKKELENTA 1011
Cdd:TIGR01612 1014 ENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYNIIDEIEKEIGKNIE--------LLNKEILEEAEINITN 1085

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1012 L-ELSQKEKQFN----AKMLEMAQANSAG-ISDAVSRLETNQKEQIESLTEVHRRELNDVisiweKKLNQQAEELQEIHE 1085
Cdd:TIGR01612 1086 FnEIKEKLKHYNfddfGKEENIKYADEINkIKDDIKNLDQKIDHHIKALEEIKKKSENYI-----DEIKAQINDLEDVAD 1160

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1086 IQLQEKEQEVAELKQKILLFGCEK-----EEMNKEITWLKEEGvKQDTTLNELQEQLKQKSAHVNSL---AQDETKLKAH 1157
Cdd:TIGR01612 1161 KAISNDDPEEIEKKIENIVTKIDKkkniyDEIKKLLNEIAEIE-KDKTSLEEVKGINLSYGKNLGKLfleKIDEEKKKSE 1239

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1158 -----LEKLEVDLNKSLKentflQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLS 1232
Cdd:TIGR01612 1240 hmikaMEAYIEDLDEIKE-----KSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISDIREKSLKIIEDF 1314

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1233 EELAIQLDICCKKTEALLEAKTNelinisSSKTNAILSRISHCQHrttkvkealLIKTCTVSELEAQLRQLTEEQNTLNi 1312
Cdd:TIGR01612 1315 SEESDINDIKKELQKNLLDAQKH------NSDINLYLNEIANIYN---------ILKLNKIKKIIDEVKEYTKEIEENN- 1378

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1313 sfQQATHQLEEKENQIKSMKADIeslvtekealqkeggNQQQAASEKESCITQlkKELSENINAVTLMKEELKEKKVEIS 1392
Cdd:TIGR01612 1379 --KNIKDELDKSEKLIKKIKDDI---------------NLEECKSKIESTLDD--KDIDECIKKIKELKNHILSEESNID 1439

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1393 SLSKQLTDLNvqlqNSISLSEKEAAISSLRKQYDEeKCELLDQVQDLSFKVDTLsKEKISALEQVDDWSNKFSEWKKKAQ 1472
Cdd:TIGR01612 1440 TYFKNADENN----ENVLLLFKNIEMADNKSQHIL-KIKKDNATNDHDFNINEL-KEHIDKSKGCKDEADKNAKAIEKNK 1513

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1473 SRFTQHQNTVKEL---QIQLELKSKEAYEKDEQINLLKEELDQQNKRFdcLKGEMEDDKSKMEKKEsnlETELKSQTARI 1549
Cdd:TIGR01612 1514 ELFEQYKKDVTELlnkYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFI--LEAEKSEQKIKEIKKE---KFRIEDDAAKN 1588

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1550 MELEDHITQKTIEIESL-NEVLKNYNQQKDI-----EHKELVQKLQHFQElgEEKDNRVKEAEEKILTLENQVYSMKAE- 1622
Cdd:TIGR01612 1589 DKSNKAAIDIQLSLENFeNKFLKISDIKKKIndclkETESIEKKISSFSI--DSQDTELKENGDNLNSLQEFLESLKDQk 1666

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1623 --LETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSElN 1700
Cdd:TIGR01612 1667 knIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIANKEEIESIKELIEPTIENLISSFNTNDLEGIDP-N 1745

                         1130
                   ....*....|....*..
gi 530372328  1701 TKLQEREREVHILEEKL 1717
Cdd:TIGR01612 1746 EKLEEYNTEIGDIYEEF 1762
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 368-521 3.16e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 46.23  E-value: 3.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  368 TQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMttqgeelrEQKEKSERAAFEELekalstaqk 447
Cdd:COG0542   411 EELDELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEAL--------KARWEAEKELIEEI--------- 473

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  448 teearRKLKAEMDEQ---IKTIEKTSEEERISLQQELSRVKQEVvdvmkksSEEQIAK---------LQKLHEKE---LA 512
Cdd:COG0542   474 -----QELKEELEQRygkIPELEKELAELEEELAELAPLLREEV-------TEEDIAEvvsrwtgipVGKLLEGErekLL 541


                  ....*....
gi 530372328  513 RKEQELTKK 521
Cdd:COG0542   542 NLEEELHER 550
PRK12704 PRK12704
phosphodiesterase; Provisional
 1068-1198 3.64e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.54  E-value: 3.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1068 IWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGceKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSL 1147
Cdd:PRK12704   24 VRKKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEA--KEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRK 101

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 530372328 1148 AQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTS 1198
Cdd:PRK12704  102 LELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTA 152
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 976-1723 3.99e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.81  E-value: 3.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   976 KKMEKVKQKAKEMQETL--KKKLLDQEAKLKKELENTALELSQKEKQfnakmLEMAQANSAGISDAVSRLETNQKEQies 1053
Cdd:TIGR00606  210 KYLKQYKEKACEIRDQItsKEAQLESSREIVKSYENELDPLKNRLKE-----IEHNLSKIMKLDNEIKALKSRKKQM--- 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1054 ltEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNEL 1133
Cdd:TIGR00606  282 --EKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRH 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1134 QEQLKQKSAHVNSLAqdetkLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSS 1213
Cdd:TIGR00606  360 QEHIRARDSLIQSLA-----TRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1214 HEKSNKSLEDKSLEFKKLSEELAI------QLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALL 1287
Cdd:TIGR00606  435 KKGLGRTIELKKEILEKKQEELKFvikelqQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLD 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1288 IKTCTVSELEAQLRQLTEEQNTLnisfQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLK 1367
Cdd:TIGR00606  515 RKLRKLDQEMEQLNHHTTTRTQM----EMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTR 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1368 KELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCEL-------------LD 1434
Cdd:TIGR00606  591 DRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRamlagatavysqfIT 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1435 QVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQN 1514
Cdd:TIGR00606  671 QLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELR 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1515 KRFDCLKGEMEDDKSKMEKKESNLETELKSQTA----------------RIMELEDHITQKTIEIESLN-----EVLKNY 1573
Cdd:TIGR00606  751 NKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESakvcltdvtimerfqmELKDVERKIAQQAAKLQGSDldrtvQQVNQE 830

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1574 NQQKDIEHKELVQKLQHFQELGEE----------KDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEE 1643
Cdd:TIGR00606  831 KQEKQHELDTVVSKIELNRKLIQDqqeqiqhlksKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQ 910

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1644 LKALEDRLE------SESAAKLAELKRKAEQKIAAIKKQ----------LLSQMEEKEEQYKKGTESHLSELNTKLQERE 1707
Cdd:TIGR00606  911 DSPLETFLEkdqqekEELISSKETSNKKAQDKVNDIKEKvknihgymkdIENKIQDGKDDYLKQKETELNTVNAQLEECE 990

                          810
                   ....*....|....*.
gi 530372328  1708 REVHILEEKLKSVESS 1723
Cdd:TIGR00606  991 KHQEKINEDMRLMRQD 1006
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
298-682 4.30e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.80  E-value: 4.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  298 TSVKTLETLQQRVKRQENL---LKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAK 374
Cdd:PRK02224  231 QARETRDEADEVLEEHEERreeLETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAE 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  375 NLIEQLE--QDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKekseraafEELEKALSTAQKTEEAR 452
Cdd:PRK02224  311 AVEARREelEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEA--------AELESELEEAREAVEDR 382

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  453 RKLKAEMDEQIKTIEKT----------SEEERISLQQELSRVKQEVVDVMK--KSSEEQIAKLQKLHEkelARKEQELTK 520
Cdd:PRK02224  383 REEIEELEEEIEELRERfgdapvdlgnAEDFLEELREERDELREREAELEAtlRTARERVEEAEALLE---AGKCPECGQ 459

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  521 KLQTRER-EFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTES-ENKLRDLQQEAETYRTRILELESSL 598
Cdd:PRK02224  460 PVEGSPHvETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERlEERREDLEELIAERRETIEEKRERA 539

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  599 EkSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKT---ELESLKHQQDALWT-EKLQVLKQQYQTEMEKLREKCEQ- 673
Cdd:PRK02224  540 E-ELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAElnsKLAELKERIESLERiRTLLAAIADAEDEIERLREKREAl 618

                         410
                  ....*....|
gi 530372328  674 -EKETLLKDK 682
Cdd:PRK02224  619 aELNDERRER 628
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 335-532 4.84e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 4.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  335 TSEKEALQEQLDE---RLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDkgmvIAETKRQMHETlemkEEEIAQLRS 411
Cdd:COG4942    19 ADAAAEAEAELEQlqqEIAELEKELAALKKEEKALLKQLAALERRIAALARR----IRALEQELAAL----EAELAELEK 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  412 RIKQMTTQGEELREQKEKSERAA-----------------FEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEE-- 472
Cdd:COG4942    91 EIAELRAELEAQKEELAELLRALyrlgrqpplalllspedFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEle 170

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530372328  473 -----------ERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLheKELARKEQELTKKLQTREREFQEQ 532
Cdd:COG4942   171 aeraeleallaELEEERAALEALKAERQKLLARLEKELAELAAEL--AELQQEAEELEALIARLEAEAAAA 239
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 871-1102 5.18e-04

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 45.23  E-value: 5.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   871 KKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYES-KLEDGNKEQEQtkQILVEKENMILQMREGQKKEIEIL 949
Cdd:pfam09726  393 KPDALVRLEQDIKKLKAELQASRQTEQELRSQISSLTSLERSlKSELGQLRQEN--DLLQTKLHNAVSAKQKDKQTVQQL 470

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   950 TQKLSAKEDSI----HILNEEYETKFKNQEKKMEKVKQKA---KEMQETLKKKLLDQEAKLKK-------------ELEN 1009
Cdd:pfam09726  471 EKRLKAEQEARasaeKQLAEEKKRKKEEEATAARAVALAAasrGECTESLKQRKRELESEIKKlthdiklkeeqirELEI 550

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1010 TALELSQKEKqfNAKMLEMAQANSAGISDAVSRLEtnqkeqiESLTEVHRRELnDVISiwekKLNQQAEELqEIHEIQLQ 1089
Cdd:pfam09726  551 KVQELRKYKE--SEKDTEVLMSALSAMQDKNQHLE-------NSLSAETRIKL-DLFS----ALGDAKRQL-EIAQGQIY 615

                          250
                   ....*....|...
gi 530372328  1090 EKEQEVAELKQKI 1102
Cdd:pfam09726  616 QKDQEIKDLKQKI 628
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
376-536 5.42e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 45.23  E-value: 5.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  376 LIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQ-KEKSERAafEELEKALSTAQKteEARRK 454
Cdd:COG2433   385 LIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAElEEKDERI--ERLERELSEARS--EERRE 460

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  455 LKaemdeqiKTIEKTSEEERIS-LQQELSRVKQEVvdvmkKSSEEQIAKLQKLHEKElARKEQELTKKLQ--TRE--REF 529
Cdd:COG2433   461 IR-------KDREISRLDREIErLERELEEERERI-----EELKRKLERLKELWKLE-HSGELVPVKVVEkfTKEaiRRL 527


                  ....*..
gi 530372328  530 QEQMKVA 536
Cdd:COG2433   528 EEEYGLK 534
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 720-908 6.55e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 6.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  720 KARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQqvdsiIKEHEVSIQRTEKALKD---QINQLELLLKERDKHLKE 796
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQ-----LAALERRIAALARRIRAleqELAALEAELAELEKEIAE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  797 HQAHVENLEADIKR------------------SEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERI 858
Cdd:COG4942    95 LRAELEAQKEELAEllralyrlgrqpplalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 530372328  859 LLTKQVAEVEAQKKdvctELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQ 908
Cdd:COG4942   175 ELEALLAELEEERA----ALEALKAERQKLLARLEKELAELAAELAELQQ 220
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1416-2043 6.89e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.11  E-value: 6.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1416 AAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVddwsnkFSEWKKKAQSRFTQHQNTVKELQIQLELKSKE 1495
Cdd:pfam15921  220 SAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELL------LQQHQDRIEQLISEHEVEITGLTEKASSARSQ 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1496 AYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEkkeSNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQ 1575
Cdd:pfam15921  294 ANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLR---SELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQ 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1576 qkdiEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESES 1655
Cdd:pfam15921  371 ----ESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQM 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1656 AAKLAELKRKAE--QKIAAIKKQLLSQMEE-----KEEQYKKGT----ESHLSELNTKLQEREREVHILEEKLKSVESSQ 1724
Cdd:pfam15921  447 ERQMAAIQGKNEslEKVSSLTAQLESTKEMlrkvvEELTAKKMTlessERTVSDLTASLQEKERAIEATNAEITKLRSRV 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1725 SETLIVPRSAKNVAAYTEQEEADSQGcVQKTYEEKISVLQRNLTEKEKLLQRVGQ----------EKEETVSSHFEMRCQ 1794
Cdd:pfam15921  527 DLKLQELQHLKNEGDHLRNVQTECEA-LKLQMAEKDKVIEILRQQIENMTQLVGQhgrtagamqvEKAQLEKEINDRRLE 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1795 YQERLIKLEHAEAKQHEDQSMIGHLQEEleeknkKYSLIVAQHVEKEGGKNNIQAKQNL----ENVFDDVQKTLQEKELT 1870
Cdd:pfam15921  606 LQEFKILKDKKDAKIRELEARVSDLELE------KVKLVNAGSERLRAVKDIKQERDQLlnevKTSRNELNSLSEDYEVL 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1871 CQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLvqpkllSNMEAQHNDL 1950
Cdd:pfam15921  680 KRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQI------DALQSKIQFL 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1951 EFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQ---ELEILKKEydqerEEKIKQEQEDLELKHNSTLKQLMREFNTQL 2027
Cdd:pfam15921  754 EEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKmagELEVLRSQ-----ERRLKEKVANMEVALDKASLQFAECQDIIQ 828

                          650
                   ....*....|....*.
gi 530372328  2028 AQKEQELEMTIKETIN 2043
Cdd:pfam15921  829 RQEQESVRLKLQHTLD 844
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1564-1716 7.18e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.85  E-value: 7.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1564 ESLNEVLKnynqqkDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVysmkAELETKKKELEHvnlSVKSKEEE 1643
Cdd:COG2433   376 LSIEEALE------ELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQV----ERLEAEVEELEA---ELEEKDER 442

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530372328 1644 LKALEDRLESESAAKLAELKRKAE-QKIAAIKKQLLSQMEEKEEqykkgtesHLSELNTKLqEREREVHILEEK 1716
Cdd:COG2433   443 IERLERELSEARSEERREIRKDREiSRLDREIERLERELEEERE--------RIEELKRKL-ERLKELWKLEHS 507
46 PHA02562
endonuclease subunit; Provisional
 1132-1375 8.64e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.23  E-value: 8.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1132 ELQEQLKQKSAHVNSLaqdETKLKAHlEKLEVDLNKSLKEN-TFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSL 1210
Cdd:PHA02562  178 ELNQQIQTLDMKIDHI---QQQIKTY-NKNIEEQRKKNGENiARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDP 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1211 KSSHEKSNKSLEDKSLEFKKLSEELAIQLD--ICCKKTEALLEakTNELINisssktnAILSRISHCQHRTTKVKEAlli 1288
Cdd:PHA02562  254 SAALNKLNTAAAKIKSKIEQFQKVIKMYEKggVCPTCTQQISE--GPDRIT-------KIKDKLKELQHSLEKLDTA--- 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1289 ktctVSELEAQLRQLTEEQNTLNisfqqathqleEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKK 1368
Cdd:PHA02562  322 ----IDELEEIMDEFNEQSKKLL-----------ELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQD 386


                  ....*..
gi 530372328 1369 ELSENIN 1375
Cdd:PHA02562  387 ELDKIVK 393
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1493-1726 1.32e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1493 SKEAYEKDEQINLLKEELDQQNKRFDCLKGE---MEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLnev 1569
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEekaLLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL--- 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1570 lknyNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEhvnlSVKSKEEELKALED 1649
Cdd:COG4942    96 ----RAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAE----ELRADLAELAALRA 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530372328 1650 RLESESAAKLAELKRKAEQkiaaiKKQLLSQMEEKEEQYKKgTESHLSELNTKLQEREREVHILEEKLKSVESSQSE 1726
Cdd:COG4942   168 ELEAERAELEALLAELEEE-----RAALEALKAERQKLLAR-LEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1153-2011 1.60e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 43.81  E-value: 1.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1153 KLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEfKKLS 1232
Cdd:pfam02463  170 KKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQE-LLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1233 EELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNI 1312
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1313 SFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEIS 1392
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1393 S---LSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDwSNKFSEWKK 1469
Cdd:pfam02463  409 LlleLARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ-LVKLQEQLE 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1470 KAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTA-- 1547
Cdd:pfam02463  488 LLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKlv 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1548 RIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAE------EKILTLENQVYSMKA 1621
Cdd:pfam02463  568 RALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEgilkdtELTKLKESAKAKESG 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1622 ELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNT 1701
Cdd:pfam02463  648 LRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRV 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1702 KLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKisvlQRNLTEKEKLLQRVGQEK 1781
Cdd:pfam02463  728 QEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEK----LKVEEEKEEKLKAQEEEL 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1782 EETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMigHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQ 1861
Cdd:pfam02463  804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEE--LALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1862 KTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRnkptelleenteEKSKSHLVQPKLLS 1941
Cdd:pfam02463  882 QKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEE------------EPEELLLEEADEKE 949

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1942 NMEAQHNDLEFKLAGAEREKQKLGKEIVRLqkDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELK 2011
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLAKEELGKVNLMA--IEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
PRK01156 PRK01156
chromosome segregation protein; Provisional
 776-1372 1.67e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 43.74  E-value: 1.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  776 LKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQ---SATHEQTKAYEEQLAQLQQKLLD 852
Cdd:PRK01156  188 LEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALnelSSLEDMKNRYESEIKTAESDLSM 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  853 LETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQnSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKE 932
Cdd:PRK01156  268 ELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENK-KQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKS 346

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  933 nmilqmregQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEA--KLKKELENT 1010
Cdd:PRK01156  347 ---------RYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAikKELNEINVK 417

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1011 ALELSQKEKQFNAKMLEMAQaNSAGISDAVSRLETNQKEQIESlTEVHRRELNDVISIWEKKLNQQAEELQEIhEIQLQE 1090
Cdd:PRK01156  418 LQDISSKVSSLNQRIRALRE-NLDELSRNMEMLNGQSVCPVCG-TTLGEEKSNHIINHYNEKKSRLEEKIREI-EIEVKD 494

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1091 KEQEVAELKQkiLLFGCEKEEMNKEITwlkeegvkQDTTLNELQEQLKQKSAHVNSLAQDETKLKA--------HLEKLE 1162
Cdd:PRK01156  495 IDEKIVDLKK--RKEYLESEEINKSIN--------EYNKIESARADLEDIKIKINELKDKHDKYEEiknrykslKLEDLD 564

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1163 VDLNKSLKENTFLQEQLVE-LKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEF---KKLSEELAIQ 1238
Cdd:PRK01156  565 SKRTSWLNALAVISLIDIEtNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLnnkYNEIQENKIL 644

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1239 LDICCKKTEALLEaKTNELINISSSKtNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQAT 1318
Cdd:PRK01156  645 IEKLRGKIDNYKK-QIAEIDSIIPDL-KEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDIN 722

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....
gi 530372328 1319 HQLEEKenqiKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSE 1372
Cdd:PRK01156  723 ETLESM----KKIKKAIGDLKRLREAFDKSGVPAMIRKSASQAMTSLTRKYLFE 772
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1130-1721 1.69e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.51  E-value: 1.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1130 LNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELkmlaEEDKRKVSELTSKLKTTDEEFQS 1209
Cdd:PRK03918  167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPEL----REELEKLEKEVKELEELKEEIEE 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1210 LK---SSHEKSNKSLEDKSLEFKKLSEELaiqldiccKKTEALLEAKTNELINISSSKTNAIlsRISHCQHRTTKVKEAL 1286
Cdd:PRK03918  243 LEkelESLEGSKRKLEEKIRELEERIEEL--------KKEIEELEEKVKELKELKEKAEEYI--KLSEFYEEYLDELREI 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1287 LIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLvteKEALQKEGGNQQQAASEKESCITQL 1366
Cdd:PRK03918  313 EKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELY---EEAKAKKEELERLKKRLTGLTPEKL 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1367 KKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNvqlQNSISLSEKEAAISSLRKQYDEEkcELLDQVQDLSFKVDTL 1446
Cdd:PRK03918  390 EKELEELEKAKEEIEEEISKITARIGELKKEIKELK---KAIEELKKAKGKCPVCGRELTEE--HRKELLEEYTAELKRI 464

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1447 SKEKISALEQVDDWSNKFSEWKK--KAQSRFTQHQNTVKELqiqlelksKEAYEKDEQINLlkEELDQQNKRFDCLKGEM 1524
Cdd:PRK03918  465 EKELKEIEEKERKLRKELRELEKvlKKESELIKLKELAEQL--------KELEEKLKKYNL--EELEKKAEEYEKLKEKL 534

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1525 eddkSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKdNRVKE 1604
Cdd:PRK03918  535 ----IKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEY-LELKD 609

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1605 AEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQlLSQMEEK 1684
Cdd:PRK03918  610 AEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAE-LEELEKR 688

                         570       580       590
                  ....*....|....*....|....*....|....*..
gi 530372328 1685 EEQYKKGTEShLSELNTKLQEREREVHILEEKLKSVE 1721
Cdd:PRK03918  689 REEIKKTLEK-LKEELEEREKAKKELEKLEKALERVE 724
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 159-410 2.07e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.40  E-value: 2.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  159 EQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQS---QDKSL-RRIAELREELQMDQQAKKHLQeEFDA 234
Cdd:COG3096   839 AALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQAnllADETLaDRLEELREELDAAQEAQAFIQ-QHGK 917

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  235 SLEEKDQYISVLQT---QVSLLKQRLRNGPMNVDVLKplPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTlETLQQRVK 311
Cdd:COG3096   918 ALAQLEPLVAVLQSdpeQFEQLQADYLQAKEQQRRLK--QQIFALSEVVQRRPHFSYEDAVGLLGENSDLN-EKLRARLE 994

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  312 RQENLLKRCKETIQSHKEQC-------TLLTSEKEALQEQLDERLQELEKIK---DLHMAEKTK-----LITQLRDAKNL 376
Cdd:COG3096   995 QAEEARREAREQLRQAQAQYsqynqvlASLKSSRDAKQQTLQELEQELEELGvqaDAEAEERARirrdeLHEELSQNRSR 1074

                         250       260       270
                  ....*....|....*....|....*....|....
gi 530372328  377 IEQLEQDKGMVIAETKrQMHETLEMKEEEIAQLR 410
Cdd:COG3096  1075 RSQLEKQLTRCEAEMD-SLQKRLRKAERDYKQER 1107
PRK12704 PRK12704
phosphodiesterase; Provisional
 336-473 2.13e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.23  E-value: 2.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  336 SEKEALQEQLDERLQELEKIKDLhmaeKTKLITQLRDAKNLIEQLEQdKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQ 415
Cdd:PRK12704   47 AKKEAEAIKKEALLEAKEEIHKL----RNEFEKELRERRNELQKLEK-RLLQKEENLDRKLELLEKREEELEKKEKELEQ 121

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530372328  416 MTTQGEELREQKEKSERAAFEELEK--ALSTAQKT----EEARRKLKAEMDEQIKTIEKTSEEE 473
Cdd:PRK12704  122 KQQELEKKEEELEELIEEQLQELERisGLTAEEAKeillEKVEEEARHEAAVLIKEIEEEAKEE 185
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1509-1680 2.39e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 2.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1509 ELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDiehkeLVQKL 1588
Cdd:COG1579    14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLG-----NVRNN 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1589 QHFQELGEEKDNrvkeAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESA---AKLAELKRK 1665
Cdd:COG1579    89 KEYEALQKEIES----LKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAeleAELEELEAE 164

                         170
                  ....*....|....*
gi 530372328 1666 AEQKIAAIKKQLLSQ 1680
Cdd:COG1579   165 REELAAKIPPELLAL 179
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
786-1210 2.43e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 2.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  786 LLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERIL-----L 860
Cdd:COG4717    51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLlqllpL 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  861 TKQVAEVEAQKKDVCTELDAHKIQVQDLmQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMRE 940
Cdd:COG4717   131 YQELEALEAELAELPERLEELEERLEEL-RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLA 209

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  941 GQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKA-------KEMQETLKKKLLDQEAKLKKELENTALE 1013
Cdd:COG4717   210 ELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIaaallalLGLGGSLLSLILTIAGVLFLVLGLLALL 289

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1014 LSQKEKQFNAKMLEMAQANSAGISDAVSRLE-TNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKE 1092
Cdd:COG4717   290 FLLLAREKASLGKEAEELQALPALEELEEEElEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELE 369

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1093 QEVAELKQKillFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQ--KSAHVNSLAQDETKLKAHLEKLEVDLNKSLK 1170
Cdd:COG4717   370 QEIAALLAE---AGVEDEEELRAALEQAEEYQELKEELEELEEQLEEllGELEELLEALDEEELEEELEELEEELEELEE 446

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|..
gi 530372328 1171 ENTFLQEQLVELK--MLAEEDKRKVSELTSKLKTTDEEFQSL 1210
Cdd:COG4717   447 ELEELREELAELEaeLEQLEEDGELAELLQELEELKAELREL 488
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1940-2116 2.55e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1940 LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKE----YDQEREEKIK----QEQEDLELK 2011
Cdd:COG4942    57 LAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELlralYRLGRQPPLAlllsPEDFLDAVR 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 2012 HNSTLKQLMREFNTQLAQKEQELEM--TIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEiLDARE 2089
Cdd:COG4942   137 RLQYLKYLAPARREQAEELRADLAElaALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAE-LAAEL 215

                         170       180
                  ....*....|....*....|....*..
gi 530372328 2090 EEMTAKVRDLQTQLEELQKKYQQKLEQ 2116
Cdd:COG4942   216 AELQQEAEELEALIARLEAEAAAAAER 242
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 301-504 3.03e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 3.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  301 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKD----LHMAEKTKLITQLRDAKNL 376
Cdd:COG4942    55 KQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRalyrLGRQPPLALLLSPEDFLDA 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  377 IEQLEQDKGmvIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERaafeELEKALSTAQKTEEARRKLK 456
Cdd:COG4942   135 VRRLQYLKY--LAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERA----ALEALKAERQKLLARLEKEL 208

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 530372328  457 AEMDEQIKTIEKtseeERISLQQELSRVKQEVVDVMKKSSEEQIAKLQ 504
Cdd:COG4942   209 AELAAELAELQQ----EAEELEALIARLEAEAAAAAERTPAAGFAALK 252
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1944-2154 3.85e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 3.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1944 EAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRK-------------------EHQQELEILKKEYDQERE-----E 1999
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQErrealqrlaeyswdeidvaSAEREIAELEAELERLDAssddlA 688

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 2000 KIKQEQEDLELKHNsTLKQLMREFNTQLAQKEQELEmTIKETINKAQEVEAELLESHQEETNQLL-KKIAEKDDDlkRTA 2078
Cdd:COG4913   689 ALEEQLEELEAELE-ELEEELDELKGEIGRLEKELE-QAEEELDELQDRLEAAEDLARLELRALLeERFAAALGD--AVE 764

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 2079 KRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGN----DNTQLAQKTTLISDSKL--KEQEFREQIHNLE 2152
Cdd:COG4913   765 RELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDadleSLPEYLALLDRLEEDGLpeYEERFKELLNENS 844


                  ..
gi 530372328 2153 DR 2154
Cdd:COG4913   845 IE 846
PRK12704 PRK12704
phosphodiesterase; Provisional
 925-1093 3.98e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 3.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  925 KQILVEKENMILQMREGQKKEIEILTQK--LSAKEDsIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEaK 1002
Cdd:PRK12704   30 EAKIKEAEEEAKRILEEAKKEAEAIKKEalLEAKEE-IHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLE-K 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1003 LKKELENTALELSQKEKQFNAKMLEMAQAnsagISDAVSRLetnqkEQIESLTEVHRRELndVISIWEKKLNQQAEELqe 1082
Cdd:PRK12704  108 REEELEKKEKELEQKQQELEKKEEELEEL----IEEQLQEL-----ERISGLTAEEAKEI--LLEKVEEEARHEAAVL-- 174

                         170
                  ....*....|.
gi 530372328 1083 IHEIQLQEKEQ 1093
Cdd:PRK12704  175 IKEIEEEAKEE 185
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1532-1710 4.26e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 4.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1532 EKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIE--HKELVQKLQHFQELgEEKDNRVKEAEEKI 1609
Cdd:COG4913   616 EAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVAsaEREIAELEAELERL-DASSDDLAALEEQL 694

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1610 LTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKqllsqmEEKEEQYK 1689
Cdd:COG4913   695 EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALG------DAVERELR 768

                         170       180
                  ....*....|....*....|.
gi 530372328 1690 KGTESHLSELNTKLQEREREV 1710
Cdd:COG4913   769 ENLEERIDALRARLNRAEEEL 789
PRK09039 PRK09039
peptidoglycan -binding protein;
356-520 4.39e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 41.88  E-value: 4.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  356 KDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAetkrQMHETLEMKEEEiaqlRSRIKQMTTQGEELREQKEKseRAAf 435
Cdd:PRK09039   51 KDSALDRLNSQIAELADLLSLERQGNQDLQDSVA----NLRASLSAAEAE----RSRLQALLAELAGAGAAAEG--RAG- 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  436 eELEKALSTAQKT-EEARRKLkAEMDEQIKtiektseeeriSLQQELSRVkQEVVDVMKKSSEEQIAKLQKLHEK---EL 511
Cdd:PRK09039  120 -ELAQELDSEKQVsARALAQV-ELLNQQIA-----------ALRRQLAAL-EAALDASEKRDRESQAKIADLGRRlnvAL 185


                  ....*....
gi 530372328  512 ARKEQELTK 520
Cdd:PRK09039  186 AQRVQELNR 194
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 301-1744 4.55e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 42.35  E-value: 4.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   301 KTLETLQQRVKRQENLLKRCKETIQSHKE--QCTLLTSEKEALQEQLDERLQELEKIKDLHmAEKTKLITQLRDAKNLIE 378
Cdd:TIGR01612 1129 HHIKALEEIKKKSENYIDEIKAQINDLEDvaDKAISNDDPEEIEKKIENIVTKIDKKKNIY-DEIKKLLNEIAEIEKDKT 1207

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   379 QLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFE-------------------ELE 439
Cdd:TIGR01612 1208 SLEEVKGINLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEmgiemdikaemetfnishdDDK 1287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   440 KALSTAQKTEEARRKLKaemDEQIKTIEKTSEEERI-----SLQQELSRVKQEVVDVMKKSSE----EQIAKLQKLheKE 510
Cdd:TIGR01612 1288 DHHIISKKHDENISDIR---EKSLKIIEDFSEESDIndikkELQKNLLDAQKHNSDINLYLNEianiYNILKLNKI--KK 1362

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   511 LARKEQELTKKLQtrerEFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAIltesenklRDLQQEAETYRTR 590
Cdd:TIGR01612 1363 IIDEVKEYTKEIE----ENNKNIKDELDKSEKLIKKIKDDINLEECKSKIESTLDDKDI--------DECIKKIKELKNH 1430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   591 ILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEK-------HKTELESLKHQQD------------ALWTE 651
Cdd:TIGR01612 1431 ILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILKIKkdnatndHDFNINELKEHIDkskgckdeadknAKAIE 1510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   652 KLQVLKQQYQTEMEKLREK-----CEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLE 726
Cdd:TIGR01612 1511 KNKELFEQYKKDVTELLNKysalaIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDK 1590

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   727 EELSVLKDQTDkmKQELEAKMDEQKNhHQQQVDSIIKEHEvSIQRTEKALkdQINQLELLLKERDKHLKEHQAHVENLEA 806
Cdd:TIGR01612 1591 SNKAAIDIQLS--LENFENKFLKISD-IKKKINDCLKETE-SIEKKISSF--SIDSQDTELKENGDNLNSLQEFLESLKD 1664

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   807 DIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVaeVEAQKKDVCTELDAHKIQVQ 886
Cdd:TIGR01612 1665 QKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIANKEEIESIKEL--IEPTIENLISSFNTNDLEGI 1742

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   887 DLMQQLEKQNSEMEQKVKSLTQVYE---SKLEDGNKEQ---EQTKQILVEKENMILQMREGQKK-----------EIEIL 949
Cdd:TIGR01612 1743 DPNEKLEEYNTEIGDIYEEFIELYNiiaGCLETVSKEPityDEIKNTRINAQNEFLKIIEIEKKsksylddieakEFDRI 1822

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   950 TQKLSAKEDSIHI-LNEEYET---KFKNQEKKMEKVKQKAKE---------MQETLKKKLLDQEAKLKKELENTALELSQ 1016
Cdd:TIGR01612 1823 INHFKKKLDHVNDkFTKEYSKineGFDDISKSIENVKNSTDEnllfdilnkTKDAYAGIIGKKYYSYKDEAEKIFINISK 1902

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1017 KEKQFNAKMlemaqANSAGIS-------DAVSRLETNQKEQI----------ESLTEVhRRELNDVISIWEKKLNQQAEE 1079
Cdd:TIGR01612 1903 LANSINIQI-----QNNSGIDlfdniniAILSSLDSEKEDTLkfipspekepEIYTKI-RDSYDTLLDIFKKSQDLHKKE 1976

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1080 LQEIHEI----QLQEKEQEVAELKQKILLFGCEKEEMNKEITWLkeegVKQDTTLNELQEQLKQKSAHVNSLAQDETKLK 1155
Cdd:TIGR01612 1977 QDTLNIIfenqQLYEKIQASNELKDTLSDLKYKKEKILNDVKLL----LHKFDELNKLSCDSQNYDTILELSKQDKIKEK 2052

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1156 A-----HLEKLEVDLNKSLKENTFLQ-----EQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKS 1225
Cdd:TIGR01612 2053 IdnyekEKEKFGIDFDVKAMEEKFDNdikdiEKFENNYKHSEKDNHDFSEEKDNIIQSKKKLKELTEAFNTEIKIIEDKI 2132

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1226 LEFKKLSEELAIQLDICCKKTEA-LLEAKTNELINISSSKTNAilsrishcqhrttkvkeallikTCTVSELEAQLRQLT 1304
Cdd:TIGR01612 2133 IEKNDLIDKLIEMRKECLLFSYAtLVETLKSKVINHSEFITSA----------------------AKFSKDFFEFIEDIS 2190

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1305 EEQNTlNISFQQATHQLEEKENQIKSMKADIESlvTEKEALQKEggnqqQAASEKESCITQLKKELSENINAVTLMKEEL 1384
Cdd:TIGR01612 2191 DSLND-DIDALQIKYNLNQTKKHMISILADATK--DHNNLIEKE-----KEATKIINNLTELFTIDFNNADADILHNNKI 2262

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1385 kekkveisslskQLTDLNVQLQNSislsekeaaISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEkisaleqvddwsnkF 1464
Cdd:TIGR01612 2263 ------------QIIYFNSELHKS---------IESIKKLYKKINAFKLLNISHINEKYFDISKE--------------F 2307

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1465 SEWKKKAQSRFTQHQNTVKELqiqlelkskEAYEKDEQINLLKEELDQQNKRFDCLKgEMEDDKSKMEKKESNLETELKS 1544
Cdd:TIGR01612 2308 DNIIQLQKHKLTENLNDLKEI---------DQYISDKKNIFLHALNENTNFNFNALK-EIYDDIINRENKADEIENINNK 2377

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1545 QTARIMELEDHITQKTIEIESL----------NEVLKNYNQQKDIEH-----KELVQKLQHFQELgeekDNRVKEAEEKI 1609
Cdd:TIGR01612 2378 ENENIMQYIDTITKLTEKIQDIlifvttyendNNIIKQHIQDNDENDvskikDNLKKTIQSFQEI----LNKIDEIKAQF 2453

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1610 LTlENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYK 1689
Cdd:TIGR01612 2454 YG-GNNINNIIITISQNANDVKNHFSKDLTIENELIQIQKRLEDIKNAAHEIRSEQITKYTNAIHNHIEEQFKKIENNSN 2532

                         1530      1540      1550      1560      1570
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 530372328  1690 KGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQE 1744
Cdd:TIGR01612 2533 KDEVYKINEIDNIIEKIINYNKEPEVKLHAIIDNKNEFASIIPDIKNLIALIESE 2587
46 PHA02562
endonuclease subunit; Provisional
 1500-1713 4.75e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 4.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1500 DEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQK-D 1578
Cdd:PHA02562  187 DMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAaK 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1579 IEHK-ELVQKLQHFQELGEE---KDNRVKEAEEKIltlenqvysmkAELETKKKELEHVNLSVKSKEEELKALEDRLeSE 1654
Cdd:PHA02562  267 IKSKiEQFQKVIKMYEKGGVcptCTQQISEGPDRI-----------TKIKDKLKELQHSLEKLDTAIDELEEIMDEF-NE 334

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530372328 1655 SAAKLAELKRKAEQKIAAIK------KQLLSQMEEKEEQYK------KGTESHLSELNTKLQEREREVHIL 1713
Cdd:PHA02562  335 QSKKLLELKNKISTNKQSLItlvdkaKKVKAAIEELQAEFVdnaeelAKLQDELDKIVKTKSELVKEKYHR 405
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 162-554 4.84e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.41  E-value: 4.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   162 IQRLRRMERSLSSY-RGKYSELVTAYQMLQREKKKLQGILSQ--SQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEE 238
Cdd:pfam15921  428 VQRLEALLKAMKSEcQGQMERQMAAIQGKNESLEKVSSLTAQleSTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQE 507

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   239 KDQYISVLQTQVSLLKQRlrngpmnVDV-LKPLPQLEPQAEVFtkeENPESDGEPV-VEDGTSVKTLETLQQRVKRQENL 316
Cdd:pfam15921  508 KERAIEATNAEITKLRSR-------VDLkLQELQHLKNEGDHL---RNVQTECEALkLQMAEKDKVIEILRQQIENMTQL 577

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   317 L---KRCKETIQSHKEQCT-------LLTSEKEALQEQLDERLQELE-KIKDLHMaEKTKLITQLRDAKNLIEQLEQDKG 385
Cdd:pfam15921  578 VgqhGRTAGAMQVEKAQLEkeindrrLELQEFKILKDKKDAKIRELEaRVSDLEL-EKVKLVNAGSERLRAVKDIKQERD 656

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   386 MVIAETKRQMHETLEMKEE-EIAQ--LRSRIKQMTTQGEELREQKeKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQ 462
Cdd:pfam15921  657 QLLNEVKTSRNELNSLSEDyEVLKrnFRNKSEEMETTTNKLKMQL-KSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQ 735

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   463 IktiekTSEEERI-SLQQELSRVKQEVVDVMKKS---SEEQIAKLQKLH----EKELARKEQELTKKLQTREREFQEQMK 534
Cdd:pfam15921  736 I-----TAKRGQIdALQSKIQFLEEAMTNANKEKhflKEEKNKLSQELStvatEKNKMAGELEVLRSQERRLKEKVANME 810

                          410       420
                   ....*....|....*....|...
gi 530372328   535 VALEKSQSEYLK---ISQEKEQQ 554
Cdd:pfam15921  811 VALDKASLQFAEcqdIIQRQEQE 833
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1071-1665 5.11e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.02  E-value: 5.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1071 KKLNQQAEELQEIHEIQLQEKEQEVAELkqkiLLFGCEKEEMNKEITWLKEEGVKQdttLNELQEQLKQKSAHVNSLAQD 1150
Cdd:pfam05483  218 KEDHEKIQHLEEEYKKEINDKEKQVSLL----LIQITEKENKMKDLTFLLEESRDK---ANQLEEKTKLQDENLKELIEK 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1151 ETKLKAHLEKLEVDLNKSLKENTFLQEQLvelkmlaEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKK 1230
Cdd:pfam05483  291 KDHLTKELEDIKMSLQRSMSTQKALEEDL-------QIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEE 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1231 LSEELAIQLDicckKTEALLEAKTNELinisssktnailsrishcQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTL 1310
Cdd:pfam05483  364 LLRTEQQRLE----KNEDQLKIITMEL------------------QKKSSELEEMTKFKNNKEVELEELKKILAEDEKLL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1311 --NISFQQATHQLEEKENQIKSMKADIESLVTEKEA-LQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEK 1387
Cdd:pfam05483  422 deKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIqLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLEN 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1388 KVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEW 1467
Cdd:pfam05483  502 KELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYE 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1468 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDC-------LKGEMEDDKSKMEKKESNLET 1540
Cdd:pfam05483  582 VLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAyeikvnkLELELASAKQKFEEIIDNYQK 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1541 ELKSQTARIMELEDHITQKTIEIESLNEVLKNYN---QQKDIEHKELVQKLQH-FQELGEEKDNRVKEAEEKiltlENQV 1616
Cdd:pfam05483  662 EIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDkrcQHKIAEMVALMEKHKHqYDKIIEERDSELGLYKNK----EQEQ 737

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*....
gi 530372328  1617 YSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRK 1665
Cdd:pfam05483  738 SSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDK 786
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 334-605 5.24e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 42.34  E-value: 5.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  334 LTSEK-EALQEQLDERLQELEKIKdlhmaeKTKLITQ-LRDAKNLIEQLEQDKGMViaETKRQMHETLEMKEEEIaQLRS 411
Cdd:PTZ00108 1099 LTKEKvEKLNAELEKKEKELEKLK------NTTPKDMwLEDLDKFEEALEEQEEVE--EKEIAKEQRLKSKTKGK-ASKL 1169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  412 RIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEqiKTIEKTSEEERISLQQELSRVKQEVVDV 491
Cdd:PTZ00108 1170 RKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSN--SSGSDQEDDEEQKTKPKKSSVKRLKSKK 1247

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  492 MKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQ------SEYLKISQEKEQQESLALEELELQ 565
Cdd:PTZ00108 1248 NNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNggskpsSPTKKKVKKRLEGSLAALKKKKKS 1327

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 530372328  566 KKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQEN 605
Cdd:PTZ00108 1328 EKKTARKKKSKTRVKQASASQSSRLLRRPRKKKSDSSSED 1367
PRK12704 PRK12704
phosphodiesterase; Provisional
 1655-1831 5.32e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 5.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1655 SAAKLAELKRKAEQKIA-------AIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKsvesSQSET 1727
Cdd:PRK12704   29 AEAKIKEAEEEAKRILEeakkeaeAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLD----RKLEL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1728 LivprSAKNVAAYTEQEEADSQgcvQKTYEEKISVLQRNLTEKEKLLQRV-GQEKEETvsshfemrcqyqeRLIKLEHAE 1806
Cdd:PRK12704  105 L----EKREEELEKKEKELEQK---QQELEKKEEELEELIEEQLQELERIsGLTAEEA-------------KEILLEKVE 164

                         170       180
                  ....*....|....*....|....*.
gi 530372328 1807 AK-QHEDQSMIGHLQEELEEKNKKYS 1831
Cdd:PRK12704  165 EEaRHEAAVLIKEIEEEAKEEADKKA 190
PRK12704 PRK12704
phosphodiesterase; Provisional
 371-510 5.41e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 5.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  371 RDAKNLIEQLEQDKGMVIAETKRQMHEtleMKEEEIAQLRSRIKQMTTQGE-ELRE------QKEKSERAAFEELEKALS 443
Cdd:PRK12704   27 KIAEAKIKEAEEEAKRILEEAKKEAEA---IKKEALLEAKEEIHKLRNEFEkELRErrnelqKLEKRLLQKEENLDRKLE 103

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530372328  444 TAQKTEEARRKLKAEMDEQIKTIEKTSEE-ERISLQQ--ELSRV--------KQEVVDVMKKSSEEQIAKLQKLHEKE 510
Cdd:PRK12704  104 LLEKREEELEKKEKELEQKQQELEKKEEElEELIEEQlqELERIsgltaeeaKEILLEKVEEEARHEAAVLIKEIEEE 181
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1953-2170 5.50e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 5.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1953 KLAGAEREKQKLGKEIVRLQKDLRMLRKEH---QQELEILKKEYDQ--EREEKIKQEQEDLELKHNSTLKQLmREFNTQL 2027
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEkalLKQLAALERRIAAlaRRIRALEQELAALEAELAELEKEI-AELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 2028 AQKEQELEMTIKETINKAQEVEAELLESHQEET---------NQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRD 2098
Cdd:COG4942   100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLdavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530372328 2099 LQTQLEELQKKYQQKLEQEENPGNDNTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNVYATTVGTP 2170
Cdd:COG4942   180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251
HlpA COG2825
Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope ...
 1958-2045 5.61e-03

Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442073 [Multi-domain]  Cd Length: 171  Bit Score: 39.82  E-value: 5.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1958 EREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDlelkhnstLKQLMREFNTQLAQKEQELEMT 2037
Cdd:COG2825    49 EKEFKKRQAELQKLEKELQALQEKLQKEAATLSEEERQKKERELQKKQQE--------LQRKQQEAQQDLQKRQQELLQP 120


                  ....*...
gi 530372328 2038 IKETINKA 2045
Cdd:COG2825   121 ILEKIQKA 128
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1941-2117 6.10e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 6.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1941 SNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEH---------QQELEILKkEYDQEREEkIKQEQEDLELK 2011
Cdd:COG3206   164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNglvdlseeaKLLLQQLS-ELESQLAE-ARAELAEAEAR 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 2012 HNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQ---LLKKIAEKDDDLKRTAKRYEEILDAR 2088
Cdd:COG3206   242 LAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDviaLRAQIAALRAQLQQEAQRILASLEAE 321

                         170       180       190
                  ....*....|....*....|....*....|.
gi 530372328 2089 EEEMTAKVRDLQTQLEELQKKYQQ--KLEQE 2117
Cdd:COG3206   322 LEALQAREASLQAQLAQLEARLAElpELEAE 352
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
302-618 6.70e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.56  E-value: 6.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  302 TLETLQQRVKRQENLLK--RCKETIQSHKEQ---CTLltSEKEALQEQLDERLQELEkikdLHMAEKTKLITQLRDAKNL 376
Cdd:PRK02224  434 TLRTARERVEEAEALLEagKCPECGQPVEGSphvETI--EEDRERVEELEAELEDLE----EEVEEVEERLERAEDLVEA 507

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  377 IEQLEQDKgmviaetkrqmhETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLK 456
Cdd:PRK02224  508 EDRIERLE------------ERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVA 575

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  457 ------AEMDEQIKTIEK--TSEEERISLQQELSRVKQevvdvmkksseeqiaKLQKLHEKELARKEQELTKKLQTRERE 528
Cdd:PRK02224  576 elnsklAELKERIESLERirTLLAAIADAEDEIERLRE---------------KREALAELNDERRERLAEKRERKRELE 640

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  529 fqeqmkvalEKSQSEYLKISQEKEQQEslaleelelqkKAILTESENKLRDLQQEAETYRTRILELESSLEkSLQENKNQ 608
Cdd:PRK02224  641 ---------AEFDEARIEEAREDKERA-----------EEYLEQVEEKLDELREERDDLQAEIGAVENELE-ELEELRER 699

                         330
                  ....*....|
gi 530372328  609 SKDLAVHLEA 618
Cdd:PRK02224  700 REALENRVEA 709
Nup88 pfam10168
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal ...
 274-506 6.72e-03

Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal two-thirds of the protein has no obvious structural motifs but is the region for binding to Nup98, one of the components of the nuclear pore. the C-terminal end is a predicted coiled-coil domain. Nup88 is overexpressed in tumour cells.


Pssm-ID: 462975 [Multi-domain]  Cd Length: 713  Bit Score: 41.57  E-value: 6.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   274 EPQAEVFTKEENPESDGEPVVEDGTS-VKTLETLQQRVKRQEnLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERlqel 352
Cdd:pfam10168  477 PPSPPLLCSKEDVTVDEPLRGLQEDSfEDHIKSILQRSVSNP-ILSADKLSSPSPQECLQLLSRATQVFREEYLKK---- 551

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   353 ekiKDLHMAEKTKLITQLRDAKnliEQLEQDKGMVIAETK--RQMHETLEMKEEEIAQ----LRSRIKQMTTQGEELREQ 426
Cdd:pfam10168  552 ---HDLAREEIQKRVKLLKLQK---EQQLQELQSLEEERKslSERAEKLAEKYEEIKDkqekLMRRCKKVLQRLNSQLPV 625

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   427 KEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEER---ISLQQELSRVKQEVVDVMKKSSEEQIAKL 503
Cdd:pfam10168  626 LSDAEREMKKELETINEQLKHLANAIKQAKKKMNYQRYQIAKSQSIRKkssLSLSEKQRKTIKEILKQLGSEIDELIKQV 705


                   ...
gi 530372328   504 QKL 506
Cdd:pfam10168  706 KDI 708
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1638-1912 6.75e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.65  E-value: 6.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1638 KSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKL 1717
Cdd:pfam17380  290 QEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEE 369

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1718 KSVESS---QSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYeekisvlQRNLTEKEKLLQRVGQEKEEtvSSHFEMRCQ 1794
Cdd:pfam17380  370 IAMEISrmrELERLQMERQQKNERVRQELEAARKVKILEEER-------QRKIQQQKVEMEQIRAEQEE--ARQREVRRL 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1795 YQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNniQAKQNLENVFDDVQKTLQEKELTCQIL 1874
Cdd:pfam17380  441 EEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEE--QRRKILEKELEERKQAMIEEERKRKLL 518

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 530372328  1875 EQKIKELDSCLVRQKEVHRVEMEELTSK--YEKLQALQQM 1912
Cdd:pfam17380  519 EKEMEERQKAIYEEERRREAEEERRKQQemEERRRIQEQM 558
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 864-982 7.25e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.74  E-value: 7.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  864 VAEVEAQKKdvctELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKE-QEQTKQILVEKENMILQMREGQ 942
Cdd:PRK00409  522 IASLEELER----ELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEaQQAIKEAKKEADEIIKELRQLQ 597

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 530372328  943 KKEI-EILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVK 982
Cdd:PRK00409  598 KGGYaSVKAHELIEARKRLNKANEKKEKKKKKQKEKQEELK 638
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1593-1721 7.56e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.35  E-value: 7.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1593 ELGEEKDnrvkEAEEKILTLENQvysmKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAA 1672
Cdd:PRK00409  510 LIGEDKE----KLNELIASLEEL----ERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQAIKE 581

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 530372328 1673 IKK---QLLSQMEEKEEQYKKGTESH-----LSELNTKLQEREREVHILEEKLKSVE 1721
Cdd:PRK00409  582 AKKeadEIIKELRQLQKGGYASVKAHelieaRKRLNKANEKKEKKKKKQKEKQEELK 638
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 342-901 7.65e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 41.70  E-value: 7.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   342 QEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIA------ETKRQMHETLEMKEEEIAQLRSRIKQ 415
Cdd:pfam01576   21 QQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAArkqeleEILHELESRLEEEEERSQQLQNEKKK 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   416 MTTQGEELREQKEKSERAafeelEKALSTAQKTEEARRKlkaEMDEQIKTIEktseEERISLQQELSRVKQEVVDVMKKS 495
Cdd:pfam01576  101 MQQHIQDLEEQLDEEEAA-----RQKLQLEKVTTEAKIK---KLEEDILLLE----DQNSKLSKERKLLEERISEFTSNL 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   496 SEEQ-----IAKLQKLHEKELARKEQELTKKLQTRERefQEQMKVALEKSQSEYlkisqekeQQESLALEELELQKKAIL 570
Cdd:pfam01576  169 AEEEekaksLSKLKNKHEAMISDLEERLKKEEKGRQE--LEKAKRKLEGESTDL--------QEQIAELQAQIAELRAQL 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   571 TESENKLRDLQQEAETYRTRilelESSLEKSLQENKNQSKDLAVHLEAEKNKHNKeitvmVEKHKTELEslkHQQDALWT 650
Cdd:pfam01576  239 AKKEEELQAALARLEEETAQ----KNNALKKIRELEAQISELQEDLESERAARNK-----AEKQRRDLG---EELEALKT 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   651 EKLQVLKQQyqTEMEKLREKCEQEKETL---LKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEE 727
Cdd:pfam01576  307 ELEDTLDTT--AAQQELRSKREQEVTELkkaLEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALES 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   728 ELSVLKDQTDKMKQeleAKMDEQknHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLlkerdkhlkehQAHVENLEAD 807
Cdd:pfam01576  385 ENAELQAELRTLQQ---AKQDSE--HKRKKLEGQLQELQARLSESERQRAELAEKLSKL-----------QSELESVSSL 448

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   808 IKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQD 887
Cdd:pfam01576  449 LNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSD 528

                          570
                   ....*....|....
gi 530372328   888 LMQQLEKQNSEMEQ 901
Cdd:pfam01576  529 MKKKLEEDAGTLEA 542
PRK12704 PRK12704
phosphodiesterase; Provisional
 1961-2092 7.88e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 7.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1961 KQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNtQLAQKEQELEMtike 2040
Cdd:PRK12704   26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEK-RLLQKEENLDR---- 100

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 530372328 2041 tinkaqevEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEM 2092
Cdd:PRK12704  101 --------KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQEL 144
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1293-1474 7.98e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.97  E-value: 7.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1293 VSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLK----- 1367
Cdd:COG3883    32 LEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGSVSYLDvllgs 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328 1368 KELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQnsiSLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLS 1447
Cdd:COG3883   112 ESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKA---ELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLS 188

                         170       180
                  ....*....|....*....|....*..
gi 530372328 1448 KEKISALEQVDDWSNKFSEWKKKAQSR 1474
Cdd:COG3883   189 AEEAAAEAQLAELEAELAAAEAAAAAA 215
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 789-1222 8.46e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 41.35  E-value: 8.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   789 ERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSAThEQTKAYEeqlaqlqQKLLDLETERILLTKQVAEVE 868
Cdd:pfam10174  182 ERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDP-AKTKALQ-------TVIEMKDTKISSLERNIRDLE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   869 AQKKDVCTELDAHKIQVQDLMQQLEKQNSE---MEQKVKSLTQvyesklEDGNKEQEQtkQILVEKENMILQMREGQKKE 945
Cdd:pfam10174  254 DEVQMLKTNGLLHTEDREEEIKQMEVYKSHskfMKNKIDQLKQ------ELSKKESEL--LALQTKLETLTNQNSDCKQH 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   946 IEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQET-------------LKKKLLDQEAK---LKKELEN 1009
Cdd:pfam10174  326 IEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLteekstlageirdLKDMLDVKERKinvLQKKIEN 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1010 TALELSQKEKQFnakmlemaqansAGISDAVSRLETNQKEQIESLTEvhrreLNDVISIWEKKLnqqaEELQEIHEIQLQ 1089
Cdd:pfam10174  406 LQEQLRDKDKQL------------AGLKERVKSLQTDSSNTDTALTT-----LEEALSEKERII----ERLKEQREREDR 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  1090 EKEQEVAELKQkillfgcEKEEMNKEITWLKEEGVKQDTTLNELQEqlkqksaHVNSLAQDETKLKAHLEKLEVDLNKSL 1169
Cdd:pfam10174  465 ERLEELESLKK-------ENKDLKEKVSALQPELTEKESSLIDLKE-------HASSLASSGLKKDSKLKSLEIAVEQKK 530

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 530372328  1170 KENTFLQEQLVELKMlAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLE 1222
Cdd:pfam10174  531 EECSKLENQLKKAHN-AEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVE 582
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 496-874 8.78e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 8.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   496 SEEQIAKLQKLHEK--ELARKEQELTKKLQTREREFQEqMKVALEKSQSEYLKISQEKEQqeslaLEELELQKKAILTES 573
Cdd:TIGR02169  669 SRSEPAELQRLRERleGLKRELSSLQSELRRIENRLDE-LSQELSDASRKIGEIEKEIEQ-----LEQEEEKLKERLEEL 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   574 ENKLRDLQQEAETYRTRILELESSLEKsLQENKNQSKDLAVHLEAEKNKHN-KEITVMVEKHKTELESLKHQQDAL--WT 650
Cdd:TIGR02169  743 EEDLSSLEQEIENVKSELKELEARIEE-LEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREIeqKL 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   651 EKLQVLKQQYQTEMEKLrekceQEKETLLKDKEIIFQAHIEEMN---EKTLEKLDVKQTELESLSSELSEVLKARHKLEE 727
Cdd:TIGR02169  822 NRLTLEKEYLEKEIQEL-----QEQRIDLKEQIKSIEKEIENLNgkkEELEEELEELEAALRDLESRLGDLKKERDELEA 896

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328   728 ELSVLKDQtdkmKQELEAKMDEQKNHHQQQvdsiikehevsiQRTEKALKDQINQLELLLKErDKHLKEHQAHVENLEAD 807
Cdd:TIGR02169  897 QLRELERK----IEELEAQIEKKRKRLSEL------------KAKLEALEEELSEIEDPKGE-DEEIPEEELSLEDVQAE 959

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530372328   808 IKRSEGELQQasakldvFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDV 874
Cdd:TIGR02169  960 LQRVEEEIRA-------LEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREV 1019
COG5022 COG5022
Myosin heavy chain [General function prediction only];
312-814 9.30e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 41.22  E-value: 9.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  312 RQENLLKRCKETIQSHKEQCTLltsEKEALQEQLDERLQELEK-IKDLHMAEKTklITQLrdaKNLIEQLEQDKGMVIAE 390
Cdd:COG5022   843 KAEVLIQKFGRSLKAKKRFSLL---KKETIYLQSAQRVELAERqLQELKIDVKS--ISSL---KLVNLELESEIIELKKS 914

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  391 TKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKT-EEARRKLKAEMDEQIKTIEKT 469
Cdd:COG5022   915 LSSDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEyEDLLKKSTILVREGNKANSEL 994

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  470 S---------EEERISLQQELSRVKQEVVDVMKKSSEEQI--------------AKLQKLHEKELARKEQELTKKLQTRE 526
Cdd:COG5022   995 KnfkkelaelSKQYGALQESTKQLKELPVEVAELQSASKIissestelsilkplQKLKGLLLLENNQLQARYKALKLRRE 1074

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  527 REFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENK 606
Cdd:COG5022  1075 NSLLDDKQLYQLESTENLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQL 1154

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  607 ---------------------NQSKDLAVHLEAEKNKhNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEME 665
Cdd:COG5022  1155 eldglfweanlealpspppfaALSEKRLYQSALYDEK-SKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISEGWVP 1233

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  666 KLREKCEQEKEtllkDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMK-QELE 744
Cdd:COG5022  1234 TEYSTSLKGFN----NLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKaSSLR 1309

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  745 AKMDEQKNHHQQQVDSIIKEHEVS-----------IQRTEKALKDQINQLELLLKERDKHLkehQAHVENLEADIKRSEG 813
Cdd:COG5022  1310 WKSATEVNYNSEELDDWCREFEISdvdeeleeliqAVKVLQLLKDDLNKLDELLDACYSLN---PAEIQNLKSRYDPADK 1386


                  .
gi 530372328  814 E 814
Cdd:COG5022  1387 E 1387
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 441-619 9.81e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.52  E-value: 9.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  441 ALSTAQKTEEARRKLKAEMDEQIKTIEKTsEEERISLQQELSRVKQEVVDVMKK--SSEEQIAKLQKlHEKELARKEQEL 518
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAAL-KKEEKALLKQLAALERRIAALARRirALEQELAALEA-ELAELEKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  519 TKKLQTREREFQEQMKVALEKSQSEYLKI---------------------------------SQEKEQQESLALEELELQ 565
Cdd:COG4942    96 RAELEAQKEELAELLRALYRLGRQPPLALllspedfldavrrlqylkylaparreqaeelraDLAELAALRAELEAERAE 175

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372328  566 KKAILTESENKLRDLQQEAETYRTRILELESSLEK------SLQENKNQSKDLAVHLEAE 619
Cdd:COG4942   176 LEALLAELEEERAALEALKAERQKLLARLEKELAElaaelaELQQEAEELEALIARLEAE 235
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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